Håvard Attramadal

  • Professor; MD
  • +47 23071396

Publications 2024

Olsen MB, Kong XY, Louwe MC, Lauritzen KH, Schanke Y, Kaasbøll OJ, Attramadal H, Øgaard J, Holm S, Aukrust P, Ryan L, Espevik T, Yurchenko M, Halvorsen B (2024)
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice
Front Immunol, 15, 1383505
DOI 10.3389/fimmu.2024.1383505, PubMed 38686379

Publications 2023

Attramadal H, Banerjee SK, Chaqour B, Fisher G, Lau L, Perbal B, Smith U, Yeger H (2023)
Report on the 11th international workshop on the CCN family of genes, Nice, October 20-24, 2022
J Cell Commun Signal, 17 (1), 7-11
DOI 10.1007/s12079-023-00731-4, PubMed 36790605

Monsen VT, Attramadal H (2023)
Structural insights into regulation of CCN protein activities and functions
J Cell Commun Signal, 17 (2), 371-390
DOI 10.1007/s12079-023-00768-5, PubMed 37245184

Tønnessen TC, Ueland T, Ahmed MS, Attramadal H, Sjaastad I, Vinge LE (2023)
Inflammatory augmentation of the delayed type hypersensitivity arthritis mouse model
Basic Clin Pharmacol Toxicol, 132 (6), 551-555
DOI 10.1111/bcpt.13864, PubMed 36946742

Publications 2022

Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BA, Ahmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G (2022)
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
Mol Biol Rep, 49 (12), 11795-11809
DOI 10.1007/s11033-022-07985-y, PubMed 36205855

Tønnessen TC, Melleby AO, Hauge-Iversen IM, Espe EKS, Ahmed MS, Ueland T, Haavardsholm EA, Atkinson SM, Melum E, Attramadal H, Sjaastad I, Vinge LE (2022)
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
PLoS One, 17 (1), e0262821
DOI 10.1371/journal.pone.0262821, PubMed 35077491

Zolfaghari S, Kaasbøll OJ, Monsen VT, Sredic B, Hagelin EMV, Attramadal H (2022)
The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2
J Biol Chem, 299 (1), 102803
DOI 10.1016/j.jbc.2022.102803, PubMed 36529291

Publications 2021

Lauritzen KH, Olsen MB, Ahmed MS, Yang K, Rinholm JE, Bergersen LH, Esbensen QY, Sverkeli LJ, Ziegler M, Attramadal H, Halvorsen B, Aukrust P, Yndestad A (2021)
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089

Zolfaghari S, Kaasbøll OJ, Ahmed MS, Line FA, Hagelin EMV, Monsen VT, Attramadal H (2021)
Tissue distribution and transcriptional regulation of CCN5 in the heart after myocardial infarction
J Cell Commun Signal, 16 (3), 377-395
DOI 10.1007/s12079-021-00659-7, PubMed 34854055

Publications 2020

Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Stølen TO, Høydal MA, Ahmed MS, Jørgensen K, Garten K, Hortigon-Vinagre MP, Zamora V, Scrimgeour NR, Berre AMO, Nes BM, Skogvoll E, Johnsen AB, Moreira JBN, McMullen JR, Attramadal H, Smith GL, Ellingsen Ø, Wisløff U (2020)
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction
J Mol Cell Cardiol, 148, 106-119
DOI 10.1016/j.yjmcc.2020.08.015, PubMed 32918915

Publications 2019

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Publications 2018

Kaasbøll OJ, Gadicherla AK, Wang JH, Monsen VT, Hagelin EMV, Dong MQ, Attramadal H (2018)
Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation
J Biol Chem, 293 (46), 17953-17970
DOI 10.1074/jbc.RA118.004559, PubMed 30262666

Publications 2017

Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840

Rutkovskiy A, Sagave J, Czibik G, Baysa A, Zihlavnikova Enayati K, Hillestad V, Dahl CP, Fiane A, Gullestad L, Gravning J, Ahmed S, Attramadal H, Valen G, Vaage J (2017)
Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans
Scand J Clin Lab Invest, 77 (5), 321-331
DOI 10.1080/00365513.2017.1318447, PubMed 28460577

Publications 2016

Kaasbøll OJ, Moe IT, Ahmed MS, Stang E, Hagelin EM, Attramadal H (2016)
CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury
PLoS One, 11 (2), e0149000
DOI 10.1371/journal.pone.0149000, PubMed 26872261

Sokolova M, Vinge LE, Alfsnes K, Olsen MB, Eide L, Kaasbøll OJ, Attramadal H, Torp MK, Fosshaug LE, Rashidi A, Lien E, Finsen AV, Sandanger Ø, Aukrust P, Ranheim T, Yndestad A (2016)
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
Biochim Biophys Acta Mol Cell Biol Lipids, 1862 (2), 234-245
DOI 10.1016/j.bbalip.2016.11.003, PubMed 27845246

Publications 2015

Dhondup Y, Sjaastad I, Scott H, Sandanger Ø, Zhang L, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521

Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
DOI 10.1152/ajpheart.00253.2014, PubMed 26055793

Lund J, Hafstad AD, Boardman NT, Rossvoll L, Rolim NP, Ahmed MS, Florholmen G, Attramadal H, Wisløff U, Larsen TS, Aasum E (2015)
Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice
Am J Physiol Heart Circ Physiol, 308 (8), H823-9
DOI 10.1152/ajpheart.00734.2014, PubMed 25637547

Morland C, Lauritzen KH, Puchades M, Holm-Hansen S, Andersson K, Gjedde A, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain
J Neurosci Res, 93 (7), 1045-55
DOI 10.1002/jnr.23593, PubMed 25881750

Sandanger Ø, Gao E, Ranheim T, Bliksøen M, Kaasbøll OJ, Alfsnes K, Nymo SH, Rashidi A, Ohm IK, Attramadal H, Aukrust P, Vinge LE, Yndestad A (2015)
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
Biochem Biophys Res Commun, 469 (4), 1012-20
DOI 10.1016/j.bbrc.2015.12.051, PubMed 26706279

Publications 2014

Askevold ET, Aukrust P, Nymo SH, Lunde IG, Kaasbøll OJ, Aakhus S, Florholmen G, Ohm IK, Strand ME, Attramadal H, Fiane A, Dahl CP, Finsen AV, Vinge LE, Christensen G, Yndestad A, Gullestad L, Latini R, Masson S, Tavazzi L, GISSI-HF Investigators, Ueland T (2014)
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105

Das MK, Basak S, Ahmed MS, Attramadal H, Duttaroy AK (2014)
Connective tissue growth factor induces tube formation and IL-8 production in first trimester human placental trophoblast cells
Eur J Obstet Gynecol Reprod Biol, 181, 183-8
DOI 10.1016/j.ejogrb.2014.07.045, PubMed 25150958

Hviid CV, Samulin Erdem J, Drechsler S, Weixelbaumer K, Ahmed MS, Attramadal H, Redl H, Bahrami S, Osuchowski MF, Aasen AO (2014)
The matricellular "cysteine-rich protein 61" is released from activated platelets and increased in the circulation during experimentally induced sepsis
Shock, 41 (3), 233-40
DOI 10.1097/SHK.0000000000000105, PubMed 24430538

Publications 2013

Gravning J, Ahmed MS, Qvigstad E, Krobert K, Edvardsen T, Moe IT, Hagelin EM, Sagave J, Valen G, Levy FO, Osnes JB, Skomedal T, Attramadal H (2013)
Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes
Mol Pharmacol, 84 (3), 372-83
DOI 10.1124/mol.113.087312, PubMed 23778361

Gravning J, Ahmed MS, von Lueder TG, Edvardsen T, Attramadal H (2013)
CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload
Int J Cardiol, 168 (3), 2049-56
DOI 10.1016/j.ijcard.2013.01.165, PubMed 23452880

Lauritzen KH, Morland C, Puchades M, Holm-Hansen S, Hagelin EM, Lauritzen F, Attramadal H, Storm-Mathisen J, Gjedde A, Bergersen LH (2013)
Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism
Cereb Cortex, 24 (10), 2784-95
DOI 10.1093/cercor/bht136, PubMed 23696276

Publications 2012

Bilbija D, Gravning JA, Haugen F, Attramadal H, Valen G (2012)
Protecting the heart through delivering DNA encoding for heme oxygenase-1 into skeletal muscle
Life Sci, 91 (17-18), 828-36
DOI 10.1016/j.lfs.2012.08.014, PubMed 22917518

Gravning J, Ørn S, Kaasbøll OJ, Martinov VN, Manhenke C, Dickstein K, Edvardsen T, Attramadal H, Ahmed MS (2012)
Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction
PLoS One, 7 (12), e52120
DOI 10.1371/journal.pone.0052120, PubMed 23284892

Hviid CV, Erdem JS, Kunke D, Ahmed SM, Kjeldsen SF, Wang YY, Attramadal H, Aasen AO (2012)
The matri-cellular proteins 'cysteine-rich, angiogenic-inducer, 61' and 'connective tissue growth factor' are regulated in experimentally-induced sepsis with multiple organ dysfunction
Innate Immun, 18 (5), 717-26
DOI 10.1177/1753425912436764, PubMed 22334618

Moe IT, Pham TA, Hagelin EM, Ahmed MS, Attramadal H (2012)
CCN2 exerts direct cytoprotective actions in adult cardiac myocytes by activation of the PI3-kinase/Akt/GSK-3β signaling pathway
J Cell Commun Signal, 7 (1), 31-47
DOI 10.1007/s12079-012-0183-1, PubMed 23208610

von Lueder TG, Gravning J, How OJ, Vinge LE, Ahmed MS, Krobert KA, Levy FO, Larsen TS, Smiseth OA, Aasum E, Attramadal H (2012)
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am J Physiol Heart Circ Physiol, 303 (1), H66-74
DOI 10.1152/ajpheart.00724.2011, PubMed 22542621

Publications 2011

Czibik G, Gravning J, Martinov V, Ishaq B, Knudsen E, Attramadal H, Valen G (2011)
Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo
Life Sci, 88 (11-12), 543-50
DOI 10.1016/j.lfs.2011.01.006, PubMed 21238463

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157

Publications 2010

Ahmed MS, Gravning J, Martinov VN, von Lueder TG, Edvardsen T, Czibik G, Moe IT, Vinge LE, Øie E, Valen G, Attramadal H (2010)
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol, 300 (4), H1291-302
DOI 10.1152/ajpheart.00604.2010, PubMed 21186275

Bergestuen DS, Gravning J, Haugaa KH, Sahakyan LG, Aakhus S, Thiis-Evensen E, Øie E, Aukrust P, Attramadal H, Edvardsen T (2010)
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
DOI 10.1186/1471-2407-10-6, PubMed 20053285

Bjørnstad JL, Sjaastad I, Nygård S, Hasic A, Ahmed MS, Attramadal H, Finsen AV, Christensen G, Tønnessen T (2010)
Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload
Eur Heart J, 32 (2), 236-45
DOI 10.1093/eurheartj/ehq166, PubMed 20525982

Øie E, Ahmed MS, Ueland T, Sikkeland LI, Dahl CP, Hagelin EM, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H (2010)
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res Cardiol, 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y, PubMed 19823891

Øie E, Sandberg WJ, Ahmed MS, Yndestad A, Lærum OD, Attramadal H, Aukrust P, Eiken HG (2010)
Activation of Notch signaling in cardiomyocytes during post-infarction remodeling
Scand Cardiovasc J, 44 (6), 359-66
DOI 10.3109/14017431.2010.511256, PubMed 20799913

Publications 2009

Attramadal H (2009)
Hypertension: Are we beta-ARKing up the right tree?
Hypertension, 54 (1), 27-8
DOI 10.1161/HYPERTENSIONAHA.109.131904, PubMed 19487585

Iversen PO, Andersson KB, Finsen AV, Sjaastad I, von Lueder TG, Sejersted OM, Attramadal H, Christensen G (2009)
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am J Physiol Regul Integr Comp Physiol, 298 (3), R808-14
DOI 10.1152/ajpregu.00250.2009, PubMed 20032264

Publications 2008

Attramadal H (2008)
Prokineticins and the heart: diverging actions elicited by signalling through prokineticin receptor-1 or -2
Cardiovasc Res, 81 (1), 3-4
DOI 10.1093/cvr/cvn306, PubMed 19008213

Publications 2007

Mehta JL, Attramadal H (2007)
The TGFbeta superfamily in cardiovascular biology
Cardiovasc Res, 74 (2), 181-3
DOI 10.1016/j.cardiores.2007.03.011, PubMed 17389143

Vinge LE, Andressen KW, Attramadal T, Andersen GØ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol Pharmacol, 72 (3), 582-91
DOI 10.1124/mol.107.035766, PubMed 17573483

Vinge LE, von Lueder TG, Aasum E, Qvigstad E, Gravning JA, How OJ, Edvardsen T, Bjørnerheim R, Ahmed MS, Mikkelsen BW, Oie E, Attramadal T, Skomedal T, Smiseth OA, Koch WJ, Larsen TS, Attramadal H (2007)
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness
J Biol Chem, 283 (16), 10601-10
DOI 10.1074/jbc.M708912200, PubMed 18165681

Publications 2006

Ahmed MS, Øie E, Vinge LE, von Lueder TG, Attramadal T, Attramadal H (2006)
Induction of pulmonary connective tissue growth factor in heart failure is associated with pulmonary parenchymal and vascular remodeling
Cardiovasc Res, 74 (2), 323-33
DOI 10.1016/j.cardiores.2006.12.010, PubMed 17254558

Andersen GO, Oie E, Vinge LE, Yndestad A, Attramadal H, Skomedal T, Osnes JB (2006)
Increased expression and function of the myocardial Na-K-2Cl cotransporter in failing rat hearts
Basic Res Cardiol, 101 (6), 471-8
DOI 10.1007/s00395-006-0604-5, PubMed 16783486

Yndestad A, Vinge LE, Bjørnerheim R, Ueland T, Wang JE, Frøland SS, Attramadal H, Aukrust P, Oie E (2006)
Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats
Eur J Heart Fail, 8 (8), 790-6
DOI 10.1016/j.ejheart.2006.02.007, PubMed 16549389

Publications 2005

Ahmed MS, von Lueder TG, Øie E, Kjekshus H, Attramadal H (2005)
Induction of myocardial connective tissue growth factor in pacing-induced heart failure in pigs
Acta Physiol Scand, 184 (1), 27-36
DOI 10.1111/j.1365-201X.2005.01416.x, PubMed 15847641

Paasche JD, Attramadal T, Kristiansen K, Oksvold MP, Johansen HK, Huitfeldt HS, Dahl SG, Attramadal H (2005)
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
Mol Pharmacol, 67 (5), 1581-90
DOI 10.1124/mol.104.007013, PubMed 15713850

Publications 2004

Ahmed MS, Øie E, Vinge LE, Yndestad A, Øystein Andersen G, Andersson Y, Attramadal T, Attramadal H (2004)
Connective tissue growth factor--a novel mediator of angiotensin II-stimulated cardiac fibroblast activation in heart failure in rats
J Mol Cell Cardiol, 36 (3), 393-404
DOI 10.1016/j.yjmcc.2003.12.004, PubMed 15010278

von Lueder TG, Kjekshus H, Edvardsen T, ØIe E, Urheim S, Vinge LE, Ahmed MS, Smiseth OA, Attramadal H (2004)
Mechanisms of elevated plasma endothelin-1 in CHF: congestion increases pulmonary synthesis and secretion of endothelin-1
Cardiovasc Res, 63 (1), 41-50
DOI 10.1016/j.cardiores.2004.03.016, PubMed 15194460

Yndestad A, Ueland T, Øie E, Florholmen G, Halvorsen B, Attramadal H, Simonsen S, Frøland SS, Gullestad L, Christensen G, Damås JK, Aukrust P (2004)
Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
DOI 10.1161/01.CIR.0000120704.97934.41, PubMed 14993131

Øie E, Vinge LE, Andersen GØ, Yndestad A, Krobert KA, Sandberg C, Ahmed MS, Haug T, Levy FO, Skomedal T, Attramadal H (2004)
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
DOI 10.1016/j.yjmcc.2004.10.009, PubMed 15623431

Publications 2003

Ahmed MS, Øie E, Vinge LE, Yndestad A, Andersen G GØ, Andersson Y, Attramadal T, Attramadal H (2003)
Induction of myocardial biglycan in heart failure in rats--an extracellular matrix component targeted by AT(1) receptor antagonism
Cardiovasc Res, 60 (3), 557-68
DOI 10.1016/j.cardiores.2003.08.017, PubMed 14659801

Publications 2002

Oie E, Clausen OP, Yndestad A, Grøgaard HK, Attramadal H (2002)
Endothelin receptor antagonism attenuates cardiomyocyte apoptosis after induction of ischemia in rats
Scand Cardiovasc J, 36 (2), 108-16
DOI 10.1080/140174302753675401, PubMed 12028875

Oie E, Yndestad A, Robins SP, Børnerheim R, Asberg A, Attramadal H (2002)
Early intervention with a potent endothelin-A/endothelin-B receptor antagonist aggravates left ventricular remodeling after myocardial infarction in rats
Basic Res Cardiol, 97 (3), 239-47
DOI 10.1007/s003950200017, PubMed 12061394

Oije E, Clausen OPF, Yndestad A, Grogaard HK, Attramadal H (2002)
Endothelin receptor antagonism attenuates cardiomyocyte apoptosis after induction of ischemia in rats
Scand. Cardiovasc. J., 36 (2), 108-116

Publications 2001

Attramadal H, Berg K (2001)
[Gene therapy in cardiovascular diseases]
Tidsskr Nor Laegeforen, 121 (4), 489-91
PubMed 11255869

Bjornerheim R, Grogaard HK, Kjekshus H, Attramadal H, Smiseth OA (2001)
High frame rate Doppler echocardiography in the rat: an evaluation of the method
Eur J Echocardiogr, 2 (2), 78-87
DOI 10.1053/euje.2000.0050, PubMed 11911099

Eiken HG, Øie E, Damås JK, Yndestad A, Bjerkeli V, Aass H, Simonsen S, Geiran OR, Tønnessen T, Christensen G, Frøland SS, Gullestad L, Attramadal H, Aukrust P (2001)
Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure
Eur J Clin Invest, 31 (5), 389-97
DOI 10.1046/j.1365-2362.2001.00795.x, PubMed 11380590

Hystad ME, Geiran OR, Attramadal H, Spurkland A, Vege A, Simonsen S, Hall C (2001)
Regional cardiac expression and concentration of natriuretic peptides in patients with severe chronic heart failure
Acta Physiol Scand, 171 (4), 395-403
DOI 10.1046/j.1365-201X.2001.00805.x, PubMed 11421854

Hystad ME, Oie E, Grøgaard HK, Kuusnemi K, Vuolteenaho O, Attramadal H, Hall C (2001)
Gene expression of natriuretic peptides and their receptors type-A and -C after myocardial infarction in rats
Scand J Clin Lab Invest, 61 (2), 139-50
DOI 10.1080/00365510151097665, PubMed 11347981

Paasche JD, Attramadal T, Sandberg C, Johansen HK, Attramadal H (2001)
Mechanisms of endothelin receptor subtype-specific targeting to distinct intracellular trafficking pathways
J Biol Chem, 276 (36), 34041-50
DOI 10.1074/jbc.M103243200, PubMed 11382773

Vinge LE, Øie E, Andersson Y, Grøgaard HK, Andersen G, Attramadal H (2001)
Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats
Am J Physiol Heart Circ Physiol, 281 (6), H2490-9
DOI 10.1152/ajpheart.2001.281.6.H2490, PubMed 11709416

Publications 2000

Attramadal H (2000)
[The mechanism of apoptosis--significance for heart failure?]
Tidsskr Nor Laegeforen, 120 (1), 62
PubMed 10815483

Bremnes T, Paasche JD, Mehlum A, Sandberg C, Bremnes B, Attramadal H (2000)
Regulation and intracellular trafficking pathways of the endothelin receptors
J Biol Chem, 275 (23), 17596-604
DOI 10.1074/jbc.M000142200, PubMed 10747877

Damås JK, Eiken HG, Oie E, Bjerkeli V, Yndestad A, Ueland T, Tonnessen T, Geiran OR, Aass H, Simonsen S, Christensen G, Froland SS, Attramadal H, Gullestad L, Aukrust P (2000)
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure
Cardiovasc Res, 47 (4), 778-87
DOI 10.1016/s0008-6363(00)00142-5, PubMed 10974226

Hystad ME, Klinge R, Spurkland A, Attramadal H, Hall C (2000)
Contrasting cardiac regional responses of A-type and B-type natriuretic peptide to experimental chronic heart failure
Scand J Clin Lab Invest, 60 (4), 299-309
DOI 10.1080/003655100750046468, PubMed 10943600

Kjekshus H, Smiseth OA, Klinge R, Oie E, Hystad ME, Attramadal H (2000)
Regulation of ET: pulmonary release of ET contributes to increased plasma ET levels and vasoconstriction in CHF
Am J Physiol Heart Circ Physiol, 278 (4), H1299-310
DOI 10.1152/ajpheart.2000.278.4.H1299, PubMed 10749728

Oie E, Bjørnerheim R, Clausen OP, Attramadal H (2000)
Cyclosporin A inhibits cardiac hypertrophy and enhances cardiac dysfunction during postinfarction failure in rats
Am J Physiol Heart Circ Physiol, 278 (6), H2115-23
DOI 10.1152/ajpheart.2000.278.6.H2115, PubMed 10843911

Oie E, Vinge LE, Yndestad A, Sandberg C, Grøgaard HK, Attramadal H (2000)
Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats
Circulation, 101 (4), 415-22
DOI 10.1161/01.cir.101.4.415, PubMed 10653834

Publications 1999

Asberg A, Attramadal H, Midtvedt K, Sund S, Hartmann A, Berg KJ (1999)
Gene expression of the renal endothelin system in renal transplant recipients on cyclosporine A based immunosuppression
Transplantation, 67 (7), 1056-60
DOI 10.1097/00007890-199904150-00020, PubMed 10221493

Publications 1998

Asberg A, Hartmann A, Attramadal H (1998)
Quantification of mRNA levels of endothelin receptor subtypes and preproEndothelin-1 in renal needle biopsies by competitive reverse transcriptase polymerase chain reaction
Scand J Clin Lab Invest, 58 (4), 299-306
DOI 10.1080/00365519850186472, PubMed 9741817

Hvaal K, Oie E, Attramadal H, Halvorsen V, Svindland A, Nordsletten L, Skjeldal S (1998)
Endothelin-1 is upregulated during skeletal muscle ischemia and reperfusion
J Orthop Res, 16 (1), 128-35
DOI 10.1002/jor.1100160122, PubMed 9565085

Oie E, Bjønerheim R, Grogaard HK, Kongshaug H, Smiseth OA, Attramadal H (1998)
ET-receptor antagonism, myocardial gene expression, and ventricular remodeling during CHF in rats
Am J Physiol, 275 (3), H868-77
DOI 10.1152/ajpheart.1998.275.3.H868, PubMed 9724291

Publications 1997

Oie E, Vinge LE, Tønnessen T, Grøgaard HK, Kjekshus H, Christensen G, Smiseth OA, Attramadal H (1997)
Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
Am J Physiol, 273 (4), H1727-36
DOI 10.1152/ajpheart.1997.273.4.H1727, PubMed 9362237

Tønnessen T, Christensen G, Oie E, Holt E, Kjekshus H, Smiseth OA, Sejersted OM, Attramadal H (1997)
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats
Cardiovasc Res, 33 (3), 601-10
DOI 10.1016/s0008-6363(96)00266-0, PubMed 9093530

Publications 1995

Eikvar L, Levy FO, Attramadal H, Hansson V (1995)
Modulation of gonadotropic and purinergic responsiveness by islet activating protein in sertoli cells from immature rats
J Steroid Biochem Mol Biol, 52 (5), 431-6
DOI 10.1016/0960-0760(95)00002-h, PubMed 7748808

Publications 1993

Dawson TM, Arriza JL, Jaworsky DE, Borisy FF, Attramadal H, Lefkowitz RJ, Ronnett GV (1993)
Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization
Science, 259 (5096), 825-9
DOI 10.1126/science.8381559, PubMed 8381559

Eikvar L, Bjørnerheim R, Attramadal H, Hansson V (1993)
Beta-adrenoceptor mediated responses and subtypes of beta-adrenoceptors in cultured rat Sertoli cells
J Steroid Biochem Mol Biol, 44 (1), 85-91
DOI 10.1016/0960-0760(93)90155-p, PubMed 8424896

Publications 1992

Attramadal H, Arriza JL, Aoki C, Dawson TM, Codina J, Kwatra MM, Snyder SH, Caron MG, Lefkowitz RJ (1992)
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family
J Biol Chem, 267 (25), 17882-90
PubMed 1517224

Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG (1992)
G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins
Cold Spring Harb Symp Quant Biol, 57, 127-33
DOI 10.1101/sqb.1992.057.01.016, PubMed 1339651

Publications 1991

Taskén KA, Knutsen HK, Attramadal H, Taskén K, Jahnsen T, Hansson V, Eskild W (1991)
Different mechanisms are involved in cAMP-mediated induction of mRNAs for subunits of cAMP-dependent protein kinases
Mol Endocrinol, 5 (1), 21-8
DOI 10.1210/mend-5-1-21, PubMed 1850108

Publications 1989

Attramadal H (1989)
Hormonal regulation of Sertoli cell adenylate cyclase: mechanisms of agonist-induced desensitization
Institute of Pathology, Rikshospitalet, [Oslo], 1 b. (flere pag.)
BIBSYS 890195730, ISBN 82-991940-0-8

Publications 1988

Attramadal H, Eikvar L, Hansson V (1988)
Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat
Endocrinology, 123 (2), 1060-8
DOI 10.1210/endo-123-2-1060, PubMed 2840261

Publications 1986

Erichsen AA, Jahnsen T, Attramadal H, Hansson V (1986)
A transplantable rat Leydig cell tumor--3. Isoproterenol and prostaglandin E1 (PGE1) responsive adenylyl cyclase (AC). Regulatory effects of nucleotides and magnesium
J Steroid Biochem, 24 (3), 761-8
DOI 10.1016/0022-4731(86)90855-1, PubMed 3702452

Jahnsen T, Attramadal H, Karpe B, Ritzen EM, Hansson V (1986)
Changes in germ cell adenylate cyclase and protein carboxyl methylase activities in rat testicular tissue during bilateral cryptorchidism and after orchidopexy
J Reprod Fertil, 77 (2), 317-20
DOI 10.1530/jrf.0.0770317, PubMed 2874225

Purvis K, Rui H, Gordeladze JO, Attramadal H (1986)
Hormonal activation of the adenylyl cyclases of the rat and human prostate gland
Prostate, 8 (1), 11-24
DOI 10.1002/pros.2990080104, PubMed 2418428

Publications 1985

Eikvar L, Levy FO, Attramadal H, Jutte NH, Frøysa A, Tvermyr SM, Hansson V (1985)
Glucagon-stimulated cyclic AMP production and formation of estradiol in Sertoli cell cultures from immature rats
Mol Cell Endocrinol, 39 (2), 107-13
DOI 10.1016/0303-7207(85)90126-1, PubMed 2984057

Le Gac F, Attramadal H, Jahnsen T, Hansson V (1985)
Studies on the mechanism of follicle-stimulating hormone-induced desensitization of Sertoli cell adenylyl cyclase in vitro
Biol Reprod, 32 (4), 916-24
DOI 10.1095/biolreprod32.4.916, PubMed 2988658

Publications 1984

Attramadal H, Jahnsen T, Hansson V (1984)
Regulation of hormone-responsive Sertoli cell adenylyl cyclase in a cell-free system
Mol Cell Endocrinol, 34 (3), 221-8
DOI 10.1016/0303-7207(84)90178-3, PubMed 6425092

Ann.NY Acad.Sci., 438 (DEC), 551-553
DOI 10.1111/j.1749-6632.1984.tb38333.x

Attramadal H, Le Gac F, Jahnsen T, Hansson V (1984)
Beta-adrenergic regulation of Sertoli cell adenylyl cyclase: desensitization by homologous hormone
Mol Cell Endocrinol, 34 (1), 1-6
DOI 10.1016/0303-7207(84)90152-7, PubMed 6321271

Ann.NY Acad.Sci., 438 (DEC), 563-565
DOI 10.1111/j.1749-6632.1984.tb38337.x

Erichsen A, Jahnsen T, Attramadal H, Andersen D, Hansson V (1984)
A transplantable rat Leydig cell tumor: binding properties, hormonal responsiveness, and tumor growth
Ann N Y Acad Sci, 438, 655-8
DOI 10.1111/j.1749-6632.1984.tb38365.x, PubMed 6100028

Erichsen A, Jahnsen T, Attramadal H, Hansson V (1984)
A transplantable rat Leydig cell tumor--2. Adenylyl cyclase activation by prostaglandin E1, isoproterenol and glucagon
J Steroid Biochem, 21 (5), 545-8
DOI 10.1016/0022-4731(84)90329-7, PubMed 6542613

Golf S, Jahnsen T, Attramadal H, Frøysaker T, Hansson V (1984)
Catecholamine responsive adenylate cyclase in human myocardial preparations. Properties and optimalization of assay conditions
Scand J Clin Lab Invest, 44 (4), 317-27
DOI 10.3109/00365518409083814, PubMed 6087439

Jahnsen T, Attramadal H, Erichsen A, Hansson V (1984)
[Hormone sensitive adenylate cyclases]
Tidsskr Nor Laegeforen, 104 (24), 1652-5
PubMed 6089373

Ann.NY Acad.Sci., 438 (DEC), 606-608
DOI 10.1111/j.1749-6632.1984.tb38350.x

Jahnsen T, Karpe B, Attramadal H, Ritzén M, Hansson V (1984)
Changes in isoproterenol-stimulated adenylate cyclase activity in rat testicular tissue during cryptorchidism and after orchidopexy
J Reprod Fertil, 70 (2), 443-8
DOI 10.1530/jrf.0.0700443, PubMed 6142113

Smith AJ, Jahnsen T, Attramadal H, Hansson V (1984)
Soluble Mn2+-dependent adenylate cyclase activity in the testis of the blue fox (Alopex lagopus)
Arch Androl, 12 (2-3), 225-30
DOI 10.3109/01485018409161180, PubMed 6508430

Publications 1983

Le Gac F, Attramadal H, Borrebaek B, Horn R, Frøysa A, Tvermyr M, Hansson V (1983)
Effects of FSH, isoproterenol, and cyclic AMP on the production of lactate and pyruvate by cultured Sertoli cells
Arch Androl, 10 (2), 149-54
DOI 10.3109/01485018308987556, PubMed 6305294

Publications 1982

Purvis K, Cusan L, Attramadal H, Ege A, Hansson V (1982)
Rat sperm enzymes during epididymal transit
J Reprod Fertil, 65 (2), 381-7
DOI 10.1530/jrf.0.0650381, PubMed 6284932

Page visits: 9808