Publications 2024

Howard JF, Bresch S, Farmakidis C, Freimer M, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Nowak RJ, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Bloemers J, Boroojerdi B, Brock M, de la Borderie G, Duda PW et al. (2024)
Long-term safety and efficacy of zilucoplan in patients with generalized myasthenia gravis: interim analysis of the RAISE-XT open-label extension study
Ther Adv Neurol Disord, 17, 17562864241243186
DOI 10.1177/17562864241243186, PubMed 38638673

Novy C, Busk ØL, Tysnes OB, Landa SS, Aanjesen TN, Alstadhaug KB, Bjerknes TL, Bjørnå IK, Bråthen G, Dahl E, Demic N, Fahlström M, Flemmen HØ, Hallerstig E, HogenEsch I, Kampman MT, Kleveland G, Kvernmo HB, Ljøstad U, Maniaol A, Morsund AH, Nakken O, Olsen CG, Schlüter K, Utvik MS et al. (2024)
Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis
Brain Commun, 6 (2), fcae087
DOI 10.1093/braincomms/fcae087, PubMed 38585669

Olsen CG, Malmberg VN, Fahlström M, Alstadhaug KB, Bjørnå IK, Braathen GJ, Bråthen G, Demic N, Hallerstig E, Hogenesch I, Horn MA, Kampman MT, Kleveland G, Ljøstad U, Maniaol A, Morsund ÅH, Nakken O, Schlüter K, Schuler S, Seim E, Flemmen HØ, Tysnes OB, Holmøy T, Høyer H (2024)
Amyotrophic lateral sclerosis caused by the C9orf72 expansion in Norway - prevalence, ancestry, clinical characteristics and sociodemographic status
Amyotroph Lateral Scler Frontotemporal Degener, 1-9 (in press)
DOI 10.1080/21678421.2024.2405118, PubMed 39316038

Weiss MD, Freimer M, Leite MI, Maniaol A, Utsugisawa K, Bloemers J, Boroojerdi B, Howard E, Savic N, Howard JF (2024)
Improvement of fatigue in generalised myasthenia gravis with zilucoplan
J Neurol, 271 (5), 2758-2767
DOI 10.1007/s00415-024-12209-3, PubMed 38400914

Publications 2023

Howard JF, Bresch S, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Lowcock R, Vanderkelen M, Leite MI, RAISE Study Team (2023)
Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study
Lancet Neurol, 22 (5), 395-406
DOI 10.1016/S1474-4422(23)00080-7, PubMed 37059508

Publications 2022

Olsen CG, Busk ØL, Aanjesen TN, Alstadhaug KB, Bjørnå IK, Braathen GJ, Breivik KL, Demic N, Flemmen HØ, Hallerstig E, HogenEsch I, Holla ØL, Jøntvedt AB, Kampman MT, Kleveland G, Kvernmo HB, Ljøstad U, Maniaol A, Morsund ÅH, Nakken O, Novy C, Rekand T, Schlüter K, Schüler S, Tveten K et al. (2022)
Genetic Epidemiology of Amyotrophic Lateral Sclerosis in Norway: A 2-Year Population-Based Study
Neuroepidemiology, 56 (4), 271-282
DOI 10.1159/000525091, PubMed 35576897

Publications 2021

Creary LE, Gangavarapu S, Caillier SJ, Cavalcante P, Frangiamore R, Lie BA, Bengtsson M, Harbo HF, Brauner S, Hollenbach JA, Oksenberg JR, Bernasconi P, Maniaol AH, Hammarström L, Mantegazza R, Fernández-Viña MA (2021)
Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations
Front Immunol, 12, 667336
DOI 10.3389/fimmu.2021.667336, PubMed 34163474

Publications 2018

Vincent A, Huda S, Cao M, Cetin H, Koneczny I, Rodriguez Cruz PM, Jacobson L, Viegas S, Jacob S, Woodhall M, Nagaishi A, Maniaol A, Damato V, Leite MI, Cossins J, Webster R, Palace J, Beeson D (2018)
Serological and experimental studies in different forms of myasthenia gravis
Ann N Y Acad Sci, 1413 (1), 143-153
DOI 10.1111/nyas.13592, PubMed 29377162

Publications 2017

Boldingh MI, Maniaol A, Brunborg C, Dekker L, Lipka A, Niks EH, Verschuuren J, Tallaksen C (2017)
Prevalence and clinical aspects of immigrants with myasthenia gravis in northern Europe
Muscle Nerve, 55 (6), 819-827
DOI 10.1002/mus.25408, PubMed 27641227

Huda S, Waters P, Woodhall M, Leite MI, Jacobson L, De Rosa A, Maestri M, Ricciardi R, Heckmann JM, Maniaol A, Evoli A, Cossins J, Hilton-Jones D, Vincent A (2017)
IgG-specific cell-based assay detects potentially pathogenic MuSK-Abs in seronegative MG
Neurol Neuroimmunol Neuroinflamm, 4 (4), e357
DOI 10.1212/NXI.0000000000000357, PubMed 28626780

Publications 2016

Boldingh MI, Maniaol AH, Brunborg C, Weedon-Fekjær H, Verschuuren JJ, Tallaksen CM (2016)
Increased risk for clinical onset of myasthenia gravis during the postpartum period
Neurology, 87 (20), 2139-2145
DOI 10.1212/WNL.0000000000003339, PubMed 27770065

Popperud TH, Boldingh MI, Brunborg C, Faiz KW, Heldal AT, Maniaol AH, Müller KI, Rasmussen M, Øymar K, Kerty E (2016)
Juvenile myasthenia gravis in Norway: A nationwide epidemiological study
Eur J Paediatr Neurol, 21 (2), 312-317
DOI 10.1016/j.ejpn.2016.09.001, PubMed 27666466

Stergiou C, Lazaridis K, Zouvelou V, Tzartos J, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Behin A, Sharshar T, De Baets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P, Szyluk B et al. (2016)
Titin antibodies in "seronegative" myasthenia gravis--A new role for an old antigen
J Neuroimmunol, 292, 108-15
DOI 10.1016/j.jneuroim.2016.01.018, PubMed 26943968

Publications 2015

Boldingh MI, Dekker L, Maniaol AH, Brunborg C, Lipka AF, Niks EH, Verschuuren JJ, Tallaksen CM (2015)
An up-date on health-related quality of life in myasthenia gravis -results from population based cohorts
Health Qual Life Outcomes, 13, 115
DOI 10.1186/s12955-015-0298-1, PubMed 26232146

Boldingh MI, Maniaol AH, Brunborg C, Dekker L, Heldal AT, Lipka AF, Popperud TH, Niks EH, Verschuuren JJ, Tallaksen CM (2015)
Geographical Distribution of Myasthenia Gravis in Northern Europe--Results from a Population-Based Study from Two Countries
Neuroepidemiology, 44 (4), 221-31
DOI 10.1159/000431036, PubMed 26068011

Seldin MF, Alkhairy OK, Lee AT, Lamb JA, Sussman J, Pirskanen-Matell R, Piehl F, Verschuuren JJGM, Kostera-Pruszczyk A, Szczudlik P, McKee D, Maniaol AH, Harbo HF, Lie BA, Melms A, Garchon HJ, Willcox N, Gregersen PK, Hammarstrom L (2015)
Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A and Identification of ZBTB10 and Three Distinct HLA Associations
Mol Med, 21 (1), 769-781
DOI 10.2119/molmed.2015.00232, PubMed 26562150

Tsonis AI, Zisimopoulou P, Lazaridis K, Tzartos J, Matsigkou E, Zouvelou V, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Behin A, Sharshar T, De Baets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A et al. (2015)
MuSK autoantibodies in myasthenia gravis detected by cell based assay--A multinational study
J Neuroimmunol, 284, 10-7
DOI 10.1016/j.jneuroim.2015.04.015, PubMed 26025053

Publications 2014

Avidan N, Le Panse R, Harbo HF, Bernasconi P, Poulas K, Ginzburg E, Cavalcante P, Colleoni L, Baggi F, Antozzi C, Truffault F, Horn-Saban S, Pöschel S, Zagoriti Z, Maniaol A, Lie BA, Bernard I, Saoudi A, Illes Z, Casasnovas Pons C, Melms A, Tzartos S, Willcox N, Kostera-Pruszczyk A, Tallaksen C et al. (2014)
VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis
Ann Clin Transl Neurol, 1 (5), 329-39
DOI 10.1002/acn3.51, PubMed 25356403

Publications 2013

Zisimopoulou P, Evangelakou P, Tzartos J, Lazaridis K, Zouvelou V, Mantegazza R, Antozzi C, Andreetta F, Evoli A, Deymeer F, Saruhan-Direskeneli G, Durmus H, Brenner T, Vaknin A, Berrih-Aknin S, Frenkian Cuvelier M, Stojkovic T, DeBaets M, Losen M, Martinez-Martinez P, Kleopa KA, Zamba-Papanicolaou E, Kyriakides T, Kostera-Pruszczyk A, Szczudlik P et al. (2013)
A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis
J Autoimmun, 52, 139-45
DOI 10.1016/j.jaut.2013.12.004, PubMed 24373505

Publications 2012

Gregersen PK, Kosoy R, Lee AT, Lamb J, Sussman J, McKee D, Simpfendorfer KR, Pirskanen-Matell R, Piehl F, Pan-Hammarstrom Q, Verschuuren JJ, Titulaer MJ, Niks EH, Marx A, Ströbel P, Tackenberg B, Pütz M, Maniaol A, Elsais A, Tallaksen C, Harbo HF, Lie BA, Raychaudhuri S, de Bakker PI, Melms A et al. (2012)
Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08
Ann Neurol, 72 (6), 927-35
DOI 10.1002/ana.23691, PubMed 23055271

Maniaol AH, Boldingh M, Brunborg C, Harbo HF, Tallaksen CME (2012)
Smoking and socio-economic status may affect myasthenia gravis
Eur J Neurol, 20 (3), 453-460
DOI 10.1111/j.1468-1331.2012.03843.x, PubMed 22934661

Maniaol AH, Elsais A, Lorentzen ÅR, Owe JF, Viken MK, Sæther H, Flåm ST, Bråthen G, Kampman MT, Midgard R, Christensen M, Rognerud A, Kerty E, Gilhus NE, Tallaksen CM, Lie BA, Harbo HF (2012)
Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian population
PLoS One, 7 (5), e36603
DOI 10.1371/journal.pone.0036603, PubMed 22590574

Publications 2011

Alseth EH, Maniaol AH, Elsais A, Nakkestad HL, Tallaksen C, Gilhus NE, Skeie GO (2011)
Investigation for RAPSN and DOK-7 mutations in a cohort of seronegative myasthenia gravis patients
Muscle Nerve, 43 (4), 574-7
DOI 10.1002/mus.21919, PubMed 21305573

Publications 2010

Maniaol AH, Brunborg C, Tallaksen CM (2010)
Development and validation of a self-administered questionnaire for myasthenia gravis patients
Neuroepidemiology, 34 (4), 253-61
DOI 10.1159/000297753, PubMed 20299807