Publications 2021

Bjaanaes MM, Sande EPS, Loe O, Ramberg C, Naess TM, Ottestad A, Rogg LV, Svestad JG, Haakensen VD (2021)
Improved adaptive radiotherapy to adjust for anatomical alterations during curative treatment for locally advanced lung cancer
Phys. Imag. Radiat. Oncol., 18, 51-54
DOI 10.1016/j.phro.2021.04.003

Farooqi SJ, Helland A, Haakensen VD, Bjaanaes MM (2021)
Immunotherapy in malignant pleural mesothelioma
Tidsskr. Nor. Laegeforen., 141 (12), 1167-1169

Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanaes MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland A (2021)
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
J. Transl. Med., 19 (1), 232
DOI 10.1186/s12967-021-02905-3

Lehtio J, Arslan T, Siavelis I, Pan YB, Socciarelli F, Berkovska O, Umer HM, Mermelekas G, Pirmoradian M, Jonsson M, Brunnstrom H, Brustugun OT, Purohit KP, Cunningham R, Asl HF, Isaksson S, Arbajian E, Aine M, Karlsson A, Kotevskaz M, Hansen CG, Haakensen VD, Helland A, Tamborero D, Johansson HJ et al. (2021)
Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms
Nat. Cancer, 2 (11), 1224-+
DOI 10.1038/s43018-021-00259-9

Terkelsen T, Pernemalm M, Gromov P, Borresen-Dale AL, Krogh A, Haakensen VD, Lethio J, Papaleo E, Gromova I (2021)
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Mol. Oncol., 15 (2), 429-461
DOI 10.1002/1878-0261.12850

Publications 2020

Haakensen VD, Khadse A, Sandhu V, Halvorsen AR, Solberg SK, Jorgensen LH, Brustugun OT, Kure EH, Helland A (2020)
Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
Int. J. Cancer, 147 (10), 2957-2966
DOI 10.1002/ijc.33121

Terkelsen T, Russo F, Gromov P, Haakensen VD, Brunak S, Gromova I, Krogh A, Papaleo E (2020)
Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
Breast Cancer Res., 22 (1), 73
DOI 10.1186/s13058-020-01295-6

Publications 2019

Bergholtz H, Lien TG, Ursin G, Holmen MM, Helland A, Sorlie T, Haakensen VD (2019)
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
J. Mammary Gland Biol. Neoplasia, 24 (2), 163-175
DOI 10.1007/s10911-018-09423-x

Dork T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, Bermisheva M, Blomqvist C, Bogdanova N, Bojesen SE, Brauch H, Brenner H, Burwinkel B, Canzian F, Chan TL et al. (2019)
Two truncating variants in FANCC and breast cancer risk
Sci Rep, 9, 12524
DOI 10.1038/s41598-019-48804-y

Jabeen S, Espinoza JA, Torland LA, Zucknick M, Kumar S, Haakensen VD, Luders T, Engebraaten O, Borresen-Dale AL, Kyte JA, Gromov P, Naume B, Kristensen V, Gromova I, Tekpli X (2019)
Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics
OncoImmunology, 8 (2), e1537691
DOI 10.1080/2162402X.2018.1537691

Nygard S, Lingjaerde OC, Caldas C, Hovig E, Borresen-Dale AL, Helland A, Haakensen VD (2019)
PathTracer: High-sensitivity detection of differential pathway activity in tumours
Sci Rep, 9, 16332
DOI 10.1038/s41598-019-52529-3

Publications 2018

Terkelsen T, Haakensen VD, Saldova R, Gromov P, Hansen MK, Stockmann H, Lingjaerde OC, Borresen-Dale AL, Papaleo E, Helland A, Rudd PM, Gromova I (2018)
N-glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome
Mol. Oncol., 12 (6), 972-990
DOI 10.1002/1878-0261.12312

Publications 2017

Dannenfelser R, Nome M, Tahiri A, Ursini-Siegel J, Vollan HKM, Haakensen VD, Helland A, Naume B, Caldas C, Borresen-Dale AL, Kristensen VN, Troyanskaya OG (2017)
Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
Oncotarget, 8 (34), 57121-57133
DOI 10.18632/oncotarget.19078

Halvorsen AR, Helland A, Gromov P, Wielenga VT, Talman MLM, Brunner N, Sandhu V, Borresen-Dale AL, Gromova I, Haakensen VD (2017)
Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer
Mol. Oncol., 11 (2), 220-234
DOI 10.1002/1878-0261.12025

Saldova R, Haakensen VD, Rodland E, Walsh I, Stockmann H, Engebraaten O, Borresen-Dale AL, Rudd PM (2017)
Serum N-glycome alterations in breast cancer during multimodal treatment and follow-up
Mol. Oncol., 11 (10), 1361-1379
DOI 10.1002/1878-0261.12105

Publications 2016

Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Marjaneh MM, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J et al. (2016)
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
Nature Genet., 48 (4), 374-+
DOI 10.1038/ng.3521

Eide HA, Halvorsen AR, Sandhu V, Fane A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland A (2016)
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
Clin. Transl. Immunol., 5, e109
DOI 10.1038/cti.2016.65

Espinoza JA, Jabeen S, Batra R, Papaleo E, Haakensen V, Wielenga VT, Talman MLM, Brunner N, Borresen-Dale AL, Gromov P, Helland A, Kristensen VN, Gromova I (2016)
Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
OncoImmunology, 5 (12), e1248015
DOI 10.1080/2162402X.2016.1248015

Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IRK, Luders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Borresen-Dale AL, Hovig E, Helland A (2016)
Subtype-specific micro-RNA expression signatures in breast cancer progression
Int. J. Cancer, 139 (5), 1117-1128
DOI 10.1002/ijc.30142

Haakensen VD, Steinfeld I, Saldova R, Shehni AA, Kifer I, Naume B, Rudd PM, Borresen-Dale AL, Yakhini Z (2016)
Serum N-glycan analysis in breast cancer patients - Relation to tumour biology and clinical outcome
Mol. Oncol., 10 (1), 59-72
DOI 10.1016/j.molonc.2015.08.002

Publications 2015

Darabi H, Mccue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D, Ghoussaini M, Bolla MK, Dennis J, Wang Q, Canisius S, Scott CG, Apicella C, Hopper JL, Southey MC, Stone J, Broeks A, Schmidt MK, Scott RJ, Lophatananon A, Muir K, Beckmann MW, Ekici AB et al. (2015)
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
Am. J. Hum. Genet., 97 (1), 22-34
DOI 10.1016/j.ajhg.2015.05.002

Potapenko IO, Luders T, Russnes HG, Helland A, Sorlie T, Kristensen VN, Nord S, Lingjaerde OC, Borresen-Dale AL, Haakensen VD (2015)
Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
Mol. Oncol., 9 (4), 861-876
DOI 10.1016/j.molonc.2014.12.013

Publications 2014

Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis MLH, Haakensen VD, Warnberg F, Naume B, Helland A, Borresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
Genome Biol., 15 (8), 435
DOI 10.1186/s13059-014-0435-x

Saldova R, Shehni AA, Haakensen VD, Steinfeld I, Hilliard M, Kifer I, Helland A, Yakhini Z, Borresen-Dale AL, Rudd PM (2014)
Association of N-Glycosylation with Breast Carcinoma and Systemic Features Using High-Resolution Quantitative UPLC
J. Proteome Res., 13 (5), 2314-2327
DOI 10.1021/pr401092y

Publications 2013

Choudhury S, Almendro V, Merino VF, Wu ZH, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
Molecular Profiling of Human Mammary Gland Links Breast Cancer Risk to a p27(+) Cell Population with Progenitor Characteristics
Cell Stem Cell, 13 (1), 117-130
DOI 10.1016/j.stem.2013.05.004

Publications 2012

Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sorlie T, Warnberg F, Haakensen VD, Helland A, Naume B, Perou CM, Haussler D, Troyanskaya OG, Borresen-Dale AL (2012)
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc. Natl. Acad. Sci. U. S. A., 109 (8), 2802-2807
DOI 10.1073/pnas.1108781108

Publications 2011

Haakensen VD (2011)
Biology of the normal breast: relation to mammographic density and risk of breast cancer
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 1137, 1 b. (flere pag.)
BIBSYS 112766811, ISBN 978-82-8264-155-5

Haakensen VD, Bjoro T, Luders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Borresen-Dale AL, Helland A (2011)
Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
BMC Cancer, 11, 332
DOI 10.1186/1471-2407-11-332

Haakensen VD, Lingjaerde OC, Luders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Borresen-Dale AL, Helland A (2011)
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
BMC Med. Genomics, 4, 77
DOI 10.1186/1755-8794-4-77

Publications 2010

Haakensen VD, Biong M, Lingjaerde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Luders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Borresen-Dale AL, Helland A (2010)
Expression levels of uridine 5 '-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
Breast Cancer Res., 12 (4), R65
DOI 10.1186/bcr2632

Potapenko IO, Haakensen VD, Luders T, Helland A, Bukholm I, Sorlie T, Kristensen VN, Lingjaerde OC, Borresen-Dale AL (2010)
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol. Oncol., 4 (2), 98-118
DOI 10.1016/j.molonc.2009.12.001

Publications 2006

Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
Int. J. Cancer, 118 (11), 2877-2881
DOI 10.1002/ijc.21709