
Rita Pinto
- Post.doc; PhD
Current main line of research:
Epigenetic heterogeneity of gastrointestinal cancers.
Academic degrees:
2015 - PhD in Biomedicine, University of Porto, Portugal
Title: CDX2 homeobox gene in cancer glycoproteome regulation
Host institutions: Institute of Molecular Pathology and Immunology of the University of Porto and Copenhagen Center for Glycomics, University of Copenhagen
2012 - MSc in Biochemistry, University of Porto, Portugal
Title: Cancer glycoproteome alterations – is there a role for CDX2?
Host institution: Institute of Molecular Pathology and Immunology of the University of Porto
Publications 2022
Effects of Maximal Exercise on Central and Peripheral Arterial Stiffness in Adults with and without Intellectual and Developmental Disabilities
FASEB J, 36 Suppl 1
DOI 10.1096/fasebj.2022.36.S1.R3579, PubMed 35556402
Publications 2021
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959
Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Nucleic Acids Res, 49 (6), 3185-3203
DOI 10.1093/nar/gkab088, PubMed 33693809
Publications 2020
Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
Int J Cancer, 148 (7), 1652-1657
DOI 10.1002/ijc.33425, PubMed 33284993
A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
Gastric Cancer, 23 (5), 811-823
DOI 10.1007/s10120-020-01064-6, PubMed 32215766
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Nucleic Acids Res, 48 (2), 830-846
DOI 10.1093/nar/gkz1147, PubMed 31799605
Publications 2019
Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration
J Biol Chem, 294 (31), 11654-11664
DOI 10.1074/jbc.RA119.009045, PubMed 31213526
Publications 2018
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
Nat Commun, 9 (1), 3411
DOI 10.1038/s41467-018-05646-y, PubMed 30143613
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase
J Biol Chem, 294 (4), 1128-1141
DOI 10.1074/jbc.RA118.005473, PubMed 30530489
Publications 2017
Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression
Nucleic Acids Res, 45 (13), e123
DOI 10.1093/nar/gkx371, PubMed 28472465
Publications 2015
CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia
Lab Invest, 95 (7), 718-27
DOI 10.1038/labinvest.2015.52, PubMed 25867765
Publications 2014
Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours
Mol Oncol, 9 (2), 503-12
DOI 10.1016/j.molonc.2014.10.005, PubMed 25454345
Publications 2012
Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation
J Cell Mol Med, 16 (7), 1474-84
DOI 10.1111/j.1582-4934.2011.01436.x, PubMed 21883895
Molecular dynamics analysis of a series of 22 potential farnesyltransferase substrates containing a CaaX-motif
J Mol Model, 19 (2), 673-88
DOI 10.1007/s00894-012-1590-1, PubMed 23011608
Publications 2011
Sialylation regulates galectin-3/ligand interplay during mammary tumour progression--a case of targeted uncloaking
Int J Dev Biol, 55 (7-9), 823-34
DOI 10.1387/ijdb.113359jt, PubMed 22161838