Rita Pinto
- Post.doc; PhD
Current main line of research:
Epigenetic heterogeneity of gastrointestinal cancers.
Academic degrees:
2015 - PhD in Biomedicine, University of Porto, Portugal
Title: CDX2 homeobox gene in cancer glycoproteome regulation
Host institutions: Institute of Molecular Pathology and Immunology of the University of Porto and Copenhagen Center for Glycomics, University of Copenhagen
2012 - MSc in Biochemistry, University of Porto, Portugal
Title: Cancer glycoproteome alterations – is there a role for CDX2?
Host institution: Institute of Molecular Pathology and Immunology of the University of Porto
Publications 2022
Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
Clin Epigenetics, 14 (1), 77
DOI 10.1186/s13148-022-01287-7, PubMed 35701814
Publications 2021
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Nat Commun, 12 (1), 891
DOI 10.1038/s41467-020-20670-7, PubMed 33563959
Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Nucleic Acids Res, 49 (6), 3185-3203
DOI 10.1093/nar/gkab088, PubMed 33693809
Publications 2020
Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
Int J Cancer, 148 (7), 1652-1657
DOI 10.1002/ijc.33425, PubMed 33284993
A panel of intestinal differentiation markers (CDX2, GPA33, and LI-cadherin) identifies gastric cancer patients with favourable prognosis
Gastric Cancer, 23 (5), 811-823
DOI 10.1007/s10120-020-01064-6, PubMed 32215766
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Nucleic Acids Res, 48 (2), 830-846
DOI 10.1093/nar/gkz1147, PubMed 31799605
Publications 2019
Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration
J Biol Chem, 294 (31), 11654-11664
DOI 10.1074/jbc.RA119.009045, PubMed 31213526
Publications 2018
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
Nat Commun, 9 (1), 3411
DOI 10.1038/s41467-018-05646-y, PubMed 30143613
Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase
J Biol Chem, 294 (4), 1128-1141
DOI 10.1074/jbc.RA118.005473, PubMed 30530489
Publications 2017
Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression
Nucleic Acids Res., 45 (13), e123
DOI 10.1093/nar/gkx371