Jan Magnus Aronsen

  • Researcher; MD, PhD
 

Publications 2022

Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Muller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2022)
AKAP18 delta Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ.Res., 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976

Publications 2021

Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front. Cardiovasc. Med., 7, 623922
DOI 10.3389/fcvm.2020.623922

Frisk M, Le C, Shen X, Roe AT, Hou YF, Manfra O, Silva GJJ, van Hout I, Norden ES, Aronsen JM, Laasmaa M, Espe EKS, Zouein FA, Lambert RR, Dahl CP, Sjaastad I, Lunde IG, Coffey S, Cataliotti A, Gullestad L, Tonnessen T, Jones PP, Altara R, Louch WE (2021)
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J. Am. Coll. Cardiol., 77 (4), 405-419
DOI 10.1016/j.jacc.2020.11.044

Wanichawan P, Skogestad J, Lunde M, Stole TP, Stensland M, Nyman TA, Sjaastad I, Sejersted OM, Aronsen JM, Carlson CR (2021)
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front. Pharmacol., 12, 638646
DOI 10.3389/fphar.2021.638646

Publications 2020

Espe EKS, Aronsen JM, Norden ES, Zhang LL, Sjaastad I (2020)
Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain
Am. J. Physiol.-Heart Circul. Physiol., 318 (1), H143-H153
DOI 10.1152/ajpheart.00357.2019

Louwe MC, Olsen MB, Kaasboll OJ, Yang K, Fosshaug LE, Alfsnes K, Ogaard JDS, Rashidi A, Skulberg VM, Yang MY, Fonseca DD, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjoras M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC-Basic Transl. Sci., 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013

Ronning SB, Carlson CR, Aronsen JM, Pisconti A, Host V, Lunde M, Liland KH, Sjaastad I, Kolset SO, Christensen G, Pedersen ME (2020)
Syndecan-4(-/-)Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
Front. Cell. Dev. Biol., 8, 730
DOI 10.3389/fcell.2020.00730

Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc. Res., 116 (1), 78-90
DOI 10.1093/cvr/cvz087

Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogested J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Oie E, Louch WE (2020)
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
Circ.Res., 126 (7), 889-906
DOI 10.1161/CIRCRESAHA.119.315641

Publications 2019

Lipsett DB, Frisk M, Aronsen JM, Norden ES, Buonarati R, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE (2019)
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J. Physiol.-London, 597 (7), 1833-1853
DOI 10.1113/JP277273

Mathiesen SB, Lunde M, Aronsen JM, Romaine A, Kaupang A, Martinsen M, de Souza GA, Nyman TA, Sjaastad I, Christensen G, Carlson CR (2019)
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J. Biol. Chem., 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423

McGinley G, Bendiksen BA, Zhang LL, Aronsen JM, Norden ES, Sjaastad I, Espe EKS (2019)
Accelerated magnetic resonance imaging tissue phase mapping of the rat myocardium using compressed sensing with iterative soft-thresholding
PLoS One, 14 (7), e0218874
DOI 10.1371/journal.pone.0218874

Mohammadzadeh N, Lunde IG, Andenaes K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygard S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tonnessen T (2019)
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9, 9206
DOI 10.1038/s41598-019-45651-9

Roe AT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Norden ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Andersen GO, Sjaastad I, Louch WE (2019)
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc. Res., 115 (4), 752-764
DOI 10.1093/cvr/cvy257

Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM (2019)
Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
Am. J. Physiol.-Heart Circul. Physiol., 316 (5), H941-H957
DOI 10.1152/ajpheart.00637.2018

Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang LL, Haugstad SB, Bendiksen BA, Lagaard J, Bliksoen M, Lien E, Berge RK, Aukrust P, Ranheim T, Yndestad A (2019)
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
Front. Immunol., 10, 1621
DOI 10.3389/fimmu.2019.01621

Publications 2018

Andenaes K, Lunde IG, Mohammadzadeh N, Dahl CP, Aronsen JM, Strand ME, Palmero S, Sjaastad I, Christensen G, Engebretsen KVT, Tonnessen T (2018)
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422

Kolstad TR, van den Brink J, MacQuaide N, Lunde PK, Frisk M, Aronsen JM, Norden ES, Cataliotti A, Sjaastad I, Sejersted OM, Edwards AG, Lines GT, Louch WE (2018)
Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes
eLife, 7, e39427
DOI 10.7554/eLife.39427

Melleby AO, Romaine A, Aronsen JM, Veras I, Zhang LL, Sjaastad I, Lunde IG, Christensen G (2018)
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc. Res., 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141

Romaine A, Sorensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D (2018)
Overexpression of integrin alpha 11 induces cardiac fibrosis in mice
Acta Physiol., 222 (2), e12932
DOI 10.1111/apha.12932

Skogestad J, Aronsen JM (2018)
Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
Front. Physiol., 9, 1500
DOI 10.3389/fphys.2018.01500

Smyrnias I, Goodwin N, Wachten D, Skogestad J, Aronsen JM, Robinson EL, Demydenko K, Segonds-Pichon A, Oxley D, Sadayappan S, Sipido K, Bootman MD, Roderick HL (2018)
Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes
J. Mol. Cell. Cardiol., 117, 1-18
DOI 10.1016/j.yjmcc.2018.02.012

Publications 2017

Aronsen JM, Espe EKS, Skardal K, Hasic A, Zhang LL, Sjaastad I (2017)
Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography
Am. J. Physiol.-Heart Circul. Physiol., 312 (5), H932-H942
DOI 10.1152/ajpheart.00668.2016

Dhondup Y, Sjaastad I, Sandanger O, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang LL, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediat. Inflamm., 2017, 9450439
DOI 10.1155/2017/9450439

Espe EKS, Aronsen JM, Eriksen M, Sejersted OM, Zhang LL, Sjaastad I (2017)
Regional Dysfunction After Myocardial Infarction in Rats
Circ.-Cardiovasc. Imaging, 10 (9), e005997
DOI 10.1161/CIRCIMAGING.116.005997

Espe EKS, Skardal K, Aronsen JM, Zhang LL, Sjaastad I (2017)
A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data
Magn. Reson. Med., 78 (3), 1199-1207
DOI 10.1002/mrm.26486

Gattoni S, Roe AT, Aronsen JM, Sjaastad I, Louch WE, Smith NP, Niederer SA (2017)
Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding
J. Physiol.-London, 595 (12), 3867-3889
DOI 10.1113/JP273879

Landfors M, Johansen J, Aronsen JM, Vagbo CB, Dore LC, He C, Sjaastad I, Saetrom P, Fedorcsak P, Dahl JA, Aanes H, Fusser M, Klungland A (2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov., 3, 170013
DOI 10.1038/celldisc.2017.13

Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur. J. Pharmacol., 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014

Roe AT, Aronsen JM, Skardal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE (2017)
Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
Cardiovasc. Res., 113 (10), 1161-1172
DOI 10.1093/cvr/cvx087

Thienpont B, Aronsen JM, Robinson EL, Okkenhaug H, Loche E, Ferrini A, Brien P, Alkass K, Tomasso A, Agrawal A, Bergmann O, Sjaastad I, Reik W, Roderick HL (2017)
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy
J. Clin. Invest., 127 (1), 335-348

Publications 2016

Aronsen JM, Louch WE, Sjaastad I (2016)
Cardiomyocyte Ca2+ dynamics: clinical perspectives
Scand. Cardiovasc. J., 50 (2), 65-77
DOI 10.3109/14017431.2015.1136079

Frisk M, Ruud M, Espe EKS, Aronsen JM, Roe AT, Zhang LL, Norseng PA, Sejersted OM, Christensen GA, Sjaastad I, Louch WE (2016)
Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis
Cardiovasc. Res., 112 (1), 443-451
DOI 10.1093/cvr/cvw111

Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2016)
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylatedPhospholemman
J. Biol. Chem., 291 (9), 4561-4579
DOI 10.1074/jbc.M115.677898

Hortemo KH, Lunde PK, Anonsen JH, Kvaloy H, Munkvik M, Rehn TA, Sjaastad I, Lunde IG, Aronsen JM, Sejersted OM (2016)
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
PHYSIOL. REP., 4 (18), e12896
DOI 10.14814/phy2.12896

Sadredini M, Danielsen TK, Aronsen JM, Manotheepan R, Hougen K, Sjaastad I, Stokke MK (2016)
Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
PLoS One, 11 (4), e0153887
DOI 10.1371/journal.pone.0153887

Skardal K, Espe EKS, Zhang LL, Aronsen JM, Sjaastad I (2016)
Three-Directional Evaluation of Mitral Flow in the Rat Heart by Phase-Contrast Cardiovascular Magnetic Resonance
PLoS One, 11 (3), e0150536
DOI 10.1371/journal.pone.0150536

Publications 2015

Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I (2015)
Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+, K+-ATPase alpha(2) activity
J. Physiol.-London, 593 (6), 1509-1521
DOI 10.1113/jphysiol.2014.279893

Dhondup Y, Sjaastad I, Scott H, Sandanger O, Zhang LL, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715

Espe EKS, Aronsen JM, Eriksen GS, Zhang LL, Smiseth OA, Edvardsen T, Sjaastad I, Eriksen M (2015)
Assessment of Regional Myocardial Work in Rats
Circ.-Cardiovasc. Imaging, 8 (2), e002695
DOI 10.1161/CIRCIMAGING.114.002695

Hortemo KH, Aronsen JM, Lunde IG, Sjaastad I, Lunde PK, Sejersted OM (2015)
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
PHYSIOL. REP., 3 (2), e12285
DOI 10.14814/phy2.12285

Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen OP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am. J. Physiol.-Heart Circul. Physiol., 309 (3), H434-H449
DOI 10.1152/ajpheart.00253.2014

Ottesen AH, Louch WE, Carlson CR, Landsverk OJB, Kurola J, Johansen RF, Moe MK, Aronsen JM, Hoiseth AD, Jarstadmarken H, Nygard S, Bjoras M, Sjaastad I, Pettila V, Stridsberg M, Omland T, Christensen G, Rosjo H (2015)
Secretoneurin Is a Novel Prognostic Cardiovascular Biomarker Associated With Cardiomyocyte Calcium Handling
J. Am. Coll. Cardiol., 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065

Strand ME, Aronsen JM, Braathen B, Sjaastad I, Kvaloy H, Tonnessen T, Christensen G, Lunde IG (2015)
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J. Mol. Cell. Cardiol., 88, 133-144
DOI 10.1016/j.yjmcc.2015.10.003

Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M (2015)
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2
Circ.Res., 117 (8), 707-719
DOI 10.1161/CIRCRESAHA.114.305892

Publications 2014

Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am. J. Physiol.-Heart Circul. Physiol., 306 (7), H1018-H1024
DOI 10.1152/ajpheart.00741.2013

Land S, Niederer SA, Louch WE, Roe AT, Aronsen JM, Stuckey DJ, Sikkel MB, Tranter MH, Lyon AR, Harding SE, Smith NP (2014)
Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying beta-adrenergic stimulation in the rat left ventricle
Am. J. Physiol.-Heart Circul. Physiol., 307 (10), H1487-H1496
DOI 10.1152/ajpheart.00443.2014

Melsom CB, Hussain RI, Orstavik O, Aronsen JM, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2014)
Non-classical regulation of beta(1)- and beta(2)-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein G(i)
Naunyn-Schmiedebergs Arch. Pharmacol., 387 (12), 1177-1186
DOI 10.1007/s00210-014-1036-7

Moltzau LR, Aronsen JM, Meier S, Skogestad J, Orstavik O, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Different Compartmentation of Responses to Brain Natriuretic Peptide and C-Type Natriuretic Peptide in Failing Rat Ventricle
J. Pharmacol. Exp. Ther., 350 (3), 681-690
DOI 10.1124/jpet.114.214882

Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
Naunyn-Schmiedebergs Arch. Pharmacol., 387 (5), 407-417
DOI 10.1007/s00210-013-0953-1

Nordbo O, Lamata P, Land S, Niederer S, Aronsen JM, Louch WE, Sjaastad I, Martens H, Gjuvsland AB, Tondel K, Torp H, Lohezic M, Schneider JE, Remme E, Smith N, Omholt SW, Vik JO (2014)
A computational pipeline for quantification of mouse myocardial stiffness parameters
Comput. Biol. Med., 53, 65-75
DOI 10.1016/j.compbiomed.2014.07.013

Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621

Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaloy H, Louch WE, Tonnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
Molecular Basis of Calpain Cleavage and Inactivation of the Sodium-Calcium Exchanger 1 in Heart Failure
J. Biol. Chem., 289 (49), 33984-33998
DOI 10.1074/jbc.M114.602581

Publications 2013

Aronsen JM, Swift F, Sejersted OM (2013)
Cardiac sodium transport and excitation-contraction coupling
J. Mol. Cell. Cardiol., 61, 11-19
DOI 10.1016/j.yjmcc.2013.06.003

Espe EKS, Aronsen JM, Skardal K, Schneider JE, Zhang LL, Sjaastad I (2013)
Novel insight into the detailed myocardial motion and deformation of the rodent heart using high-resolution phase contrast cardiovascular magnetic resonance
J. Cardiov. Magn. Reson., 15, 82
DOI 10.1186/1532-429X-15-82

Espe EKS, Aronsen JM, Skrbic B, Skulberg VM, Schneider JE, Sejersted OM, Zhang LL, Sjaastad I (2013)
Improved MR phase-contrast velocimetry using a novel nine-point balanced motion-encoding scheme with increased robustness to eddy current effects
Magn. Reson. Med., 69 (1), 48-61
DOI 10.1002/mrm.24226

Hussain RI, Aronsen JM, Afzal F, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2013)
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
J. Mol. Cell. Cardiol., 56, 129-138
DOI 10.1016/j.yjmcc.2012.11.015

Land S, Louch WE, Niederer SA, Aronsen JM, Christensen GA, Sjaastad I, Sejersted OM, Smitht NP (2013)
Beta-Adrenergic Stimulation Maintains Cardiac Function in Serca2 Knockout Mice
Biophys. J., 104 (6), 1349-1356
DOI 10.1016/j.bpj.2013.01.042

Moltzau LR, Aronsen JM, Meier S, Nguyen CHT, Hougen K, Orstavik O, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br. J. Pharmacol., 170 (2), 366-379
DOI 10.1111/bph.12282

Solberg A, Robertson AB, Aronsen JM, Rognmo O, Sjaastad I, Wisloff U, Klungland A (2013)
Deletion of mouse Alkbh7 leads to obesity
J. Mol. Cell Biol., 5 (3), 194-203
DOI 10.1093/jmcb/mjt012

Publications 2012

Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL (2012)
Mutual antagonism between IP3RII and miRNA-133a regulates calcium signals and cardiac hypertrophy
J. Cell Biol., 199 (5), 783-798
DOI 10.1083/jcb.201111095

Land S, Niederer SA, Aronsen JM, Espe EKS, Zhang LL, Louch WE, Sjaastad I, Sejersted OM, Smith NP (2012)
An analysis of deformation-dependent electromechanical coupling in the mouse heart
J. Physiol.-London, 590 (18), 4553-4569
DOI 10.1113/jphysiol.2012.231928

Li LR, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP (2012)
Sodium Accumulation in SERCA Knockout-Induced Heart Failure
Biophys. J., 102 (9), 2039-2048
DOI 10.1016/j.bpj.2012.03.045

Lunde IG, Aronsen JM, Kvaloy H, Qvigstad E, Sjaastad I, Tonnessen T, Christensen G, Gronning-Wang LM, Carlson CR (2012)
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol. Genomics, 44 (2), 162-172
DOI 10.1152/physiolgenomics.00016.2011

Publications 2011

Afzal F, Aronsen JM, Moltzau LR, Sjaastad I, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2011)
Differential regulation of beta(2)-adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
Br. J. Pharmacol., 162 (1), 54-71
DOI 10.1111/j.1476-5381.2010.00890.x

Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
Naunyn-Schmiedebergs Arch. Pharmacol., 384 (6), 543-553
DOI 10.1007/s00210-011-0670-6

Aronsen JM (2011)
Repeter!: farmakologi
Gyldendal akademisk, Oslo, 207 s.
BIBSYS 110553365, ISBN 978-82-05-40130-3

Hussain RI, Afzal F, Mork HK, Aronsen JM, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2011)
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
Br. J. Pharmacol., 162 (4), 908-916
DOI 10.1111/j.1476-5381.2010.01097.x

Munkvik M, Lunde PK, Aronsen JM, Birkeland JAK, Sjaastad I, Sejersted OM (2011)
Attenuated Fatigue in Slow Twitch Skeletal Muscle during Isotonic Exercise in Rats with Chronic Heart Failure
PLoS One, 6 (7), e22695
DOI 10.1371/journal.pone.0022695

Publications 2010

Aronsen JM (2010)
[No title]
In Repeter!: sykdomslære, Gyldendal akademisk, Oslo, 2, 235 s.
BIBSYS 102187355, ISBN 978-82-05-40079-5

Aronsen JM, Birkeland JA, Munkvik M, Sjaastad I (2010)
Repeter!: sykdomslære
Gyldendal akademisk, Oslo, 2 b.
BIBSYS 102381445

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alpha MHC-MerCreMer) mice
Am. J. Physiol.-Heart Circul. Physiol., 299 (5), H1671-H1678
DOI 10.1152/ajpheart.01155.2009

Louch WE, Hougen K, Mork HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM (2010)
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J. Physiol.-London, 588 (3), 465-478
DOI 10.1113/jphysiol.2009.183517

Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CHT, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB (2010)
Natriuretic peptides increase beta(1)-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
Cardiovasc. Res., 85 (4), 763-772
DOI 10.1093/cvr/cvp364

Publications 2009

Rehn TA, Borge BA, Lunde PK, Munkvik M, Sneve ML, Grondahl F, Aronsen JM, Sjaastad I, Prydz K, Kolset SO, Wiig H, Sejersted OM, Iversen PO (2009)
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
Am. J. Physiol.-Regul. Integr. Comp. Physiol., 297 (1), R26-R33
DOI 10.1152/ajpregu.90617.2008

Sharikabad MN, Aronsen JM, Haugen E, Pedersen J, Moller ASW, Mork HK, Aass HCD, Sejersted OM, Sjaastad I, Brors O (2009)
Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
Am. J. Physiol.-Heart Circul. Physiol., 296 (3), H787-H795
DOI 10.1152/ajpheart.00796.2008

Publications 2008

Afzal F, Andressen KW, Mork HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
Br. J. Pharmacol., 155 (7), 1005-1014
DOI 10.1038/bjp.2008.339

Bokenes J, Aronsen JM, Birkeland JA, Henriksen UL, Louch WE, Sjaastad I, Sejersted OM (2008)
Slow contractions characterize failing rat hearts
Basic Res. Cardiol., 103 (4), 328-344
DOI 10.1007/s00395-008-0719-y

Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha(2)-isoform in heart failure
Cardiovasc. Res., 78 (1), 71-78
DOI 10.1093/cvr/cvn013

Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na(+)/Ca(2+)-exchanger activity due to downregulation of Na(+)/K(+)-ATPase alpha(2)-isoform in heart failure (vol 78, pg 71, 2008)
Cardiovasc. Res., 79 (2), 352
DOI 10.1093/cvr/cvn147