Publications 2024

Combriat T, Olsen PA, Låstad SB, Malthe-Sørenssen A, Krauss S, Dysthe DK (2024)
Acoustic Wave-Induced Stroboscopic Optical Mechanotyping of Adherent Cells
Adv Sci (Weinh), 11 (16), e2307929
DOI 10.1002/advs.202307929, PubMed 38417124

Cunha AB, Schuelke C, Mesri A, Ruud SK, Aizenshtadt A, Ferrari G, Heiskanen A, Asif A, Keller SS, Ramos-Moreno T, Kalvøy H, Martínez-Serrano A, Krauss S, Emnéus J, Sampietro M, Martinsen ØG (2024)
Development of a Smart Wireless Multisensor Platform for an Optogenetic Brain Implant
Sensors (Basel), 24 (2)
DOI 10.3390/s24020575, PubMed 38257668

Hrušková H, Olsen C, Řemínek R, Wang C, Aizenshtadt A, Krauss S, Scholz H, Røberg-Larsen H, Foret F, Wilson SR (2024)
Preparative agarose gel electrophoresis for reducing matrix interferences of organoid cell medium prior to LC-MS analysis of insulin
J Chromatogr A, 1717, 464669
DOI 10.1016/j.chroma.2024.464669, PubMed 38278130

Stegmüller N, Binder K, Krauss S (2024)
How general is the natural frequency effect? The case of joint probabilities
Front Psychol, 15, 1296359
DOI 10.3389/fpsyg.2024.1296359, PubMed 38659687

Stegmüller N, Binder K, Krauss S (2024)
Corrigendum: How general is the natural frequency effect? The case of joint probabilities
Front Psychol, 15, 1515434
DOI 10.3389/fpsyg.2024.1515434, PubMed 39629193

Wang C, Abadpour S, Aizenshtadt A, Dalmao-Fernandez A, Høyem M, Wilhelmsen I, Stokowiec J, Olsen PA, Krauss S, Chera S, Ghila L, Ræder H, Scholz H (2024)
Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling
Front Bioeng Biotechnol, 12, 1392575
DOI 10.3389/fbioe.2024.1392575, PubMed 38933536

Wang C, Abadpour S, Olsen PA, Wang D, Stokowiec J, Chera S, Ghila L, Ræder H, Krauss S, Aizenshtadt A, Scholz H (2024)
Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells
Transpl Int, 37, 11900
DOI 10.3389/ti.2024.11900, PubMed 38304198

Wilhelmsen I, Combriat T, Dalmao-Fernandez A, Stokowiec J, Wang C, Olsen PA, Wik JA, Boichuk Y, Aizenshtadt A, Krauss S (2024)
The effects of TGF-β-induced activation and starvation of vitamin A and palmitic acid on human stem cell-derived hepatic stellate cells
Stem Cell Res Ther, 15 (1), 223
DOI 10.1186/s13287-024-03852-8, PubMed 39044210

Publications 2023

Abadpour S, Niemi EM, Orrhult LS, Hermanns C, de Vries R, Nogueira LP, Haugen HJ, Josefsen D, Krauss S, Gatenholm P, van Apeldoorn A, Scholz H (2023)
Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993

Busek M, Aizenshtadt A, Koch T, Frank A, Delon L, Martinez MA, Golovin A, Dumas C, Stokowiec J, Gruenzner S, Melum E, Krauss S (2023)
Pump-less, recirculating organ-on-a-chip (rOoC) platform
Lab Chip, 23 (4), 591-608
DOI 10.1039/d2lc00919f, PubMed 36655405

Dalmao-Fernandez A, Aizenshtadt A, Bakke HG, Krauss S, Rustan AC, Thoresen GH, Kase ET (2023)
Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies
Front Bioeng Biotechnol, 11, 1130693
DOI 10.3389/fbioe.2023.1130693, PubMed 37034250

Kømurcu KS, Wilhelmsen I, Thorne JL, Krauss S, Wilson SR, Aizenshtadt A, Røberg-Larsen H (2023)
Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids
J Steroid Biochem Mol Biol, 232, 106355
DOI 10.1016/j.jsbmb.2023.106355, PubMed 37380087

LaLone V, Aizenshtadt A, Goertz J, Skottvoll FS, Mota MB, You J, Zhao X, Berg HE, Stokowiec J, Yu M, Schwendeman A, Scholz H, Wilson SR, Krauss S, Stevens MM (2023)
Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
Cell Rep Methods, 3 (4), 100440
DOI 10.1016/j.crmeth.2023.100440, PubMed 37159662

Olsen C, Wang C, Aizenshtadt A, Abadpour S, Lundanes E, Skottvoll FS, Golovin A, Busek M, Krauss S, Scholz H, Wilson SR (2023)
Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids
Electrophoresis, 44 (21-22), 1682-1697
DOI 10.1002/elps.202300095, PubMed 37574258

Shoji JY, Davis RP, Mummery CL, Krauss S (2023)
Global Literature Analysis of Organoid and Organ-on-Chip Research
Adv Healthc Mater, 13 (21), e2301067
DOI 10.1002/adhm.202301067, PubMed 37479227

Steib N, Krauss S, Binder K, Büchter T, Böcherer-Linder K, Eichler A, Vogel M (2023)
Measuring people's covariational reasoning in Bayesian situations
Front Psychol, 14, 1184370
DOI 10.3389/fpsyg.2023.1184370, PubMed 37908812

Tse J, O'Keefe R, Rigopolous A, Carli ALE, Waaler J, Krauss S, Ernst M, Buchert M (2023)
A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors
Biomedicines, 11 (10)
DOI 10.3390/biomedicines11102719, PubMed 37893093

Wilhelmsen I, Amirola Martinez M, Stokowiec J, Wang C, Aizenshtadt A, Krauss S (2023)
Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture
Front Bioeng Biotechnol, 11, 1223737
DOI 10.3389/fbioe.2023.1223737, PubMed 37560536

Publications 2022

Brinch SA, Amundsen-Isaksen E, Espada S, Hammarström C, Aizenshtadt A, Olsen PA, Holmen L, Høyem M, Scholz H, Grødeland G, Sowa ST, Galera-Prat A, Lehtiö L, Meerts IATM, Leenders RGG, Wegert A, Krauss S, Waaler J (2022)
The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
Cancer Res Commun, 2 (4), 233-245
DOI 10.1158/2767-9764.CRC-22-0027, PubMed 36873622

Busek M, Aizenshtadt A, Amirola-Martinez M, Delon L, Krauss S (2022)
Academic User View: Organ-on-a-Chip Technology
Biosensors (Basel), 12 (2)
DOI 10.3390/bios12020126, PubMed 35200386

Kogler S, Aizenshtadt A, Harrison S, Skottvoll FS, Berg HE, Abadpour S, Scholz H, Sullivan G, Thiede B, Lundanes E, Bogen IL, Krauss S, Røberg-Larsen H, Wilson SR (2022)
"Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry
Anal Chem, 94 (50), 17677-17684
DOI 10.1021/acs.analchem.2c04530, PubMed 36484723

Seidel S, Cruz-Bournazou MN, Groß S, Schollmeyer JK, Kurreck A, Krauss S, Neubauer P (2022)
A Comprehensive IT Infrastructure for an Enzymatic Product Development in a Digitalized Biotechnological Laboratory
Adv Biochem Eng Biotechnol, 182, 61-82
DOI 10.1007/10_2022_207, PubMed 35861884

Vazquez P, Hirayama-Shoji K, Novik S, Krauss S, Rayner S (2022)
Globally Accessible Distributed Data Sharing (GADDS): a decentralized FAIR platform to facilitate data sharing in the life sciences
Bioinformatics, 38 (15), 3812-3817
DOI 10.1093/bioinformatics/btac362, PubMed 35639939

Publications 2021

Binder K, Krauss S, Schmidmaier R, Braun LT (2021)
Natural frequency trees improve diagnostic efficiency in Bayesian reasoning
Adv Health Sci Educ Theory Pract, 26 (3), 847-863
DOI 10.1007/s10459-020-10025-8, PubMed 33599875

Bruckmaier G, Krauss S, Binder K, Hilbert S, Brunner M (2021)
Tversky and Kahneman's Cognitive Illusions: Who Can Solve Them, and Why?
Front Psychol, 12, 584689
DOI 10.3389/fpsyg.2021.584689, PubMed 33912097

Busek M, Nøvik S, Aizenshtadt A, Amirola-Martinez M, Combriat T, Grünzner S, Krauss S (2021)
Thermoplastic Elastomer (TPE)-Poly(Methyl Methacrylate) (PMMA) Hybrid Devices for Active Pumping PDMS-Free Organ-on-a-Chip Systems
Biosensors (Basel), 11 (5)
DOI 10.3390/bios11050162, PubMed 34069506

Leenders RGG, Brinch SA, Sowa ST, Amundsen-Isaksen E, Galera-Prat A, Murthy S, Aertssen S, Smits JN, Nieczypor P, Damen E, Wegert A, Nazaré M, Lehtiö L, Waaler J, Krauss S (2021)
Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II
J Med Chem, 64 (24), 17936-17949
DOI 10.1021/acs.jmedchem.1c01264, PubMed 34878777

Mygland L, Brinch SA, Strand MF, Olsen PA, Aizenshtadt A, Lund K, Solberg NT, Lycke M, Thorvaldsen TE, Espada S, Misaghian D, Page CM, Agafonov O, Nygård S, Chi NW, Lin E, Tan J, Yu Y, Costa M, Krauss S, Waaler J (2021)
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362

Olsen PA, Krauss S (2021)
The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates
Genes (Basel), 12 (12)
DOI 10.3390/genes12121920, PubMed 34946869

Skottvoll FS, Hansen FA, Harrison S, Boger IS, Mrsa A, Restan MS, Stein M, Lundanes E, Pedersen-Bjergaard S, Aizenshtadt A, Krauss S, Sullivan G, Bogen IL, Wilson SR (2021)
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551

Zhang Y, Shen L, Dreißigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW (2021)
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease
Blood, 137 (17), 2403-2416
DOI 10.1182/blood.2020008720, PubMed 33529322

Publications 2020

Abadpour S, Aizenshtadt A, Olsen PA, Shoji K, Wilson SR, Krauss S, Scholz H (2020)
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261

Binder K, Krauss S, Wiesner P (2020)
A New Visualization for Probabilistic Situations Containing Two Binary Events: The Frequency Net
Front Psychol, 11, 750
DOI 10.3389/fpsyg.2020.00750, PubMed 32528335

Kierulf-Vieira KS, Sandberg CJ, Waaler J, Lund K, Skaga E, Saberniak BM, Panagopoulos I, Brandal P, Krauss S, Langmoen IA, Vik-Mo EO (2020)
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464

Lien VT, Kristiansen MK, Pettersen S, Haugen MH, Krauss S, Olberg DE, Waaler J, Klaveness J (2020)
Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
RSC Adv, 10 (9), 4927
DOI 10.1039/d0ra90007a, PubMed 35503286

Perdreau-Dahl H, Progida C, Barfeld SJ, Guldsten H, Thiede B, Arntzen M, Bakke O, Mills IG, Krauss S, Morth JP (2020)
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109

Wang H, Kuusela S, Rinnankoski-Tuikka R, Dumont V, Bouslama R, Ramadan UA, Waaler J, Linden AM, Chi NW, Krauss S, Pirinen E, Lehtonen S (2020)
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Int J Obes (Lond), 44 (8), 1691-1702
DOI 10.1038/s41366-020-0573-z, PubMed 32317752

Waaler J, Leenders RGG, Sowa ST, Alam Brinch S, Lycke M, Nieczypor P, Aertssen S, Murthy S, Galera-Prat A, Damen E, Wegert A, Nazaré M, Lehtiö L, Krauss S (2020)
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
J Med Chem, 63 (13), 6834-6846
DOI 10.1021/acs.jmedchem.0c00208, PubMed 32511917

Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858

Publications 2019

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481

Bruckmaier G, Binder K, Krauss S, Kufner HM (2019)
An Eye-Tracking Study of Statistical Reasoning With Tree Diagrams and 2 × 2 Tables
Front Psychol, 10, 632
DOI 10.3389/fpsyg.2019.00632, PubMed 31156488

Lin A, Sved Skottvoll F, Rayner S, Pedersen-Bjergaard S, Sullivan G, Krauss S, Ray Wilson S, Harrison S (2019)
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry
Electrophoresis, 41 (1-2), 56-64
DOI 10.1002/elps.201900170, PubMed 31544246

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Publications 2018

Habs M, Binder K, Krauss S, Müller K, Ernst B, Valentini L, Koller M (2018)
A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)-The Case of Herbal Medicinal Products Containing St. John's Wort Extracts (SJW)
Nutrients, 10 (7)
DOI 10.3390/nu10070804, PubMed 29932143

Norum JH, Skarpen E, Brech A, Kuiper R, Waaler J, Krauss S, Sørlie T (2018)
The tankyrase inhibitor G007-LK inhibits small intestine LGR5⁺ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982

Publications 2017

Anumala UR, Waaler J, Nkizinkiko Y, Ignatev A, Lazarow K, Lindemann P, Olsen PA, Murthy S, Obaji E, Majouga AG, Leonov S, von Kries JP, Lehtiö L, Krauss S, Nazaré M (2017)
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568

Habs M, Binder K, Krauss S, Müller K, Ernst B, Valentini L, Koller M (2017)
A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)-The Case of Tea and Herbal Infusions
Nutrients, 9 (7)
DOI 10.3390/nu9070717, PubMed 28686224

Lund K, Olsen CE, Wong JJW, Olsen PA, Solberg NT, Høgset A, Krauss S, Selbo PK (2017)
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S (2017)
TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer
Mol Cancer Res, 16 (3), 543-553
DOI 10.1158/1541-7786.MCR-17-0362, PubMed 29222171

Vehus T, Waaler J, Krauss S, Lundanes E, Wilson SR (2017)
Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery
LC GC Eur., 30 (5), 232-239

Publications 2016

Roberg-Larsen H, Lund K, Seterdal KE, Solheim S, Vehus T, Solberg N, Krauss S, Lundanes E, Wilson SR (2016)
Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes
J Steroid Biochem Mol Biol, 169, 22-28
DOI 10.1016/j.jsbmb.2016.02.006, PubMed 26877254

Vehus T, Roberg-Larsen H, Waaler J, Aslaksen S, Krauss S, Wilson SR, Lundanes E (2016)
Versatile, sensitive liquid chromatography mass spectrometry - Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins
Sci Rep, 6, 37507
DOI 10.1038/srep37507, PubMed 27897190

Vehus T, Seterdal KE, Krauss S, Lundanes E, Wilson SR (2016)
Comparison of commercial nanoliquid chromatography columns for fast, targeted mass spectrometry-based proteomics
Future Sci OA, 2 (2), FSO119
DOI 10.4155/fsoa-2016-0014, PubMed 28031966

Publications 2015

Haikarainen T, Waaler J, Ignatev A, Nkizinkiko Y, Venkannagari H, Obaji E, Krauss S, Lehtiö L (2015)
Development and structural analysis of adenosine site binding tankyrase inhibitors
Bioorg Med Chem Lett, 26 (2), 328-333
DOI 10.1016/j.bmcl.2015.12.018, PubMed 26706174

Lund K, Dembinski JL, Solberg N, Urbanucci A, Mills IG, Krauss S (2015)
Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment
PLoS One, 10 (4), e0123684
DOI 10.1371/journal.pone.0123684, PubMed 25860483

Machon O, Masek J, Machonova O, Krauss S, Kozmik Z (2015)
Meis2 is essential for cranial and cardiac neural crest development
BMC Dev Biol, 15, 40
DOI 10.1186/s12861-015-0093-6, PubMed 26545946

Olsen PA, Lund K, Krauss S (2015)
Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells
Genom Data, 4, 150-2
DOI 10.1016/j.gdata.2015.04.010, PubMed 26484203

Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443

Zhong L, Ding Y, Bandyopadhyay G, Waaler J, Börgeson E, Smith S, Zhang M, Phillips SA, Mahooti S, Mahata SK, Shao J, Krauss S, Chi NW (2015)
The PARsylation activity of tankyrase in adipose tissue modulates systemic glucose metabolism in mice
Diabetologia, 59 (3), 582-91
DOI 10.1007/s00125-015-3815-1, PubMed 26631215

Publications 2014

Haikarainen T, Krauss S, Lehtio L (2014)
Tankyrases: structure, function and therapeutic implications in cancer
Curr Pharm Des, 20 (41), 6472-88
DOI 10.2174/1381612820666140630101525, PubMed 24975604

Hustoft HK, Vehus T, Brandtzaeg OK, Krauss S, Greibrokk T, Wilson SR, Lundanes E (2014)
Open tubular lab-on-column/mass spectrometry for targeted proteomics of nanogram sample amounts
PLoS One, 9 (9), e106881
DOI 10.1371/journal.pone.0106881, PubMed 25222838

Lund K, Bostad M, Skarpen E, Braunagel M, Kiprijanov S, Krauss S, Duncan A, Høgset A, Selbo PK (2014)
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727

Olsen PA, Solberg NT, Lund K, Vehus T, Gelazauskaite M, Wilson SR, Krauss S (2014)
Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells
PLoS One, 9 (12), e115496
DOI 10.1371/journal.pone.0115496, PubMed 25536063

Roberg-Larsen H, Lund K, Vehus T, Solberg N, Vesterdal C, Misaghian D, Olsen PA, Krauss S, Wilson SR, Lundanes E (2014)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
J Lipid Res, 55 (7), 1531-6
DOI 10.1194/jlr.D048801, PubMed 24792927

Roberg-Larsen H, Strand MF, Krauss S, Wilson SR (2014)
Metabolites in vertebrate Hedgehog signaling
Biochem Biophys Res Commun, 446 (3), 669-74
DOI 10.1016/j.bbrc.2014.01.087, PubMed 24486313

Publications 2013

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M (2013)
A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth
Cancer Res, 73 (10), 3132-44
DOI 10.1158/0008-5472.CAN-12-4562, PubMed 23539443

Lehtiö L, Chi NW, Krauss S (2013)
Tankyrases as drug targets
FEBS J, 280 (15), 3576-93
DOI 10.1111/febs.12320, PubMed 23648170

Solberg N, Krauss S (2013)
Luciferase assay to study the activity of a cloned promoter DNA fragment
Methods Mol Biol, 977, 65-78
DOI 10.1007/978-1-62703-284-1_6, PubMed 23436354

Stratford EW, Daffinrud J, Munthe E, Castro R, Waaler J, Krauss S, Myklebost O (2013)
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines
Cancer Med, 3 (1), 36-46
DOI 10.1002/cam4.170, PubMed 24403055

Voronkov A, Holsworth DD, Waaler J, Wilson SR, Ekblad B, Perdreau-Dahl H, Dinh H, Drewes G, Hopf C, Morth JP, Krauss S (2013)
Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor
J Med Chem, 56 (7), 3012-23
DOI 10.1021/jm4000566, PubMed 23473363

Voronkov A, Krauss S (2013)
Wnt/beta-catenin signaling and small molecule inhibitors
Curr Pharm Des, 19 (4), 634-64
DOI 10.2174/138161213804581837, PubMed 23016862

Publications 2012

Holsworth DD, Krauss S (2012)
Recent Advances in Wnt/beta-Catenin Pathway Small-Molecule Inhibitors
Annu. Rep. Med. Chem., 47, 393-409
DOI 10.1016/B978-0-12-396492-2.00026-6

Roberg-Larsen H, Strand MF, Grimsmo A, Olsen PA, Dembinski JL, Rise F, Lundanes E, Greibrokk T, Krauss S, Wilson SR (2012)
High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry
J Chromatogr A, 1255, 291-7
DOI 10.1016/j.chroma.2012.02.002, PubMed 22410154

Solberg N, Machon O, Machonova O, Krauss S (2012)
Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites
Mol Cell Biochem, 365 (1-2), 53-63
DOI 10.1007/s11010-012-1243-9, PubMed 22270545

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753

Publications 2011

Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP (2011)
Insulin receptor substrate 2 is a negative regulator of memory formation
Learn Mem, 18 (6), 375-83
DOI 10.1101/lm.2111311, PubMed 21597043

Jing Y, Machon O, Hampl A, Dvorak P, Xing Y, Krauss S (2011)
In vitro differentiation of mouse embryonic stem cells into neurons of the dorsal forebrain
Cell Mol Neurobiol, 31 (5), 715-27
DOI 10.1007/s10571-011-9669-2, PubMed 21424551

Solberg N, Machon O, Krauss S (2011)
Characterization and functional analysis of the 5'-flanking promoter region of the mouse Tcf3 gene
Mol Cell Biochem, 360 (1-2), 289-99
DOI 10.1007/s11010-011-1068-y, PubMed 21935611

Strand MF, Wilson SR, Dembinski JL, Holsworth DD, Khvat A, Okun I, Petersen D, Krauss S (2011)
A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
PLoS One, 6 (6), e19904
DOI 10.1371/journal.pone.0019904, PubMed 21698280

Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S (2011)
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth
Cancer Res, 71 (1), 197-205
DOI 10.1158/0008-5472.CAN-10-1282, PubMed 21199802

Publications 2010

Dembinski JL, Krauss S (2010)
A Distinct Slow-Cycling Cancer Stem-like Subpopulation of Pancreatic Adenocarcinoma Cells is maintained in Vivo
Cancers (Basel), 2 (4), 2011-25
DOI 10.3390/cancers2042011, PubMed 24281215

Dembinski JL, Krauss S (2010)
A Distinct Slow-Cycling Cancer Stem-like Subpopulation of Pancreatic Adenocarcinoma Cells is maintained in Vivo
Cancers, 2 (4), 2011-2025
DOI 10.3390/cancers2042011, PublikaID 116

Kalousova A, Mavropoulos A, Adams BA, Nekrep N, Li Z, Krauss S, Stainier DY, German MS (2010)
Dachshund homologues play a conserved role in islet cell development
Dev Biol, 348 (2), 143-52
DOI 10.1016/j.ydbio.2010.09.007, PubMed 20869363

Olsen PA, Gelazauskaite M, Randøl M, Krauss S (2010)
Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction
BMC Mol Biol, 11, 35
DOI 10.1186/1471-2199-11-35, PubMed 20459736

Wilson SR, Strand MF, Krapp A, Rise F, Herstad G, Malterud KE, Krauss S (2010)
Hedgehog antagonists cyclopamine and dihydroveratramine can be mistaken for each other in Veratrum album
J Pharm Biomed Anal, 53 (3), 497-502
DOI 10.1016/j.jpba.2010.05.024, PubMed 20646889

Wilson SR, Strand MF, Krapp A, Rise F, Petersen D, Krauss S (2010)
Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified
J Pharm Biomed Anal, 52 (5), 707-13
DOI 10.1016/j.jpba.2010.02.017, PubMed 20236786

Publications 2009

Dembinski JL, Krauss S (2009)
Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma
Clin Exp Metastasis, 26 (7), 611-23
DOI 10.1007/s10585-009-9260-0, PubMed 19421880

Hildrestrand GA, Neurauter CG, Diep DB, Castellanos CG, Krauss S, Bjørås M, Luna L (2009)
Expression patterns of Neil3 during embryonic brain development and neoplasia
BMC Neurosci, 10, 45
DOI 10.1186/1471-2202-10-45, PubMed 19426544

Kunke D, Bryja V, Mygland L, Arenas E, Krauss S (2009)
Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs
Biochem Biophys Res Commun, 386 (4), 628-33
DOI 10.1016/j.bbrc.2009.06.084, PubMed 19545542

Publications 2008

Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S (2008)
Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases
DNA Repair (Amst), 8 (3), 298-308
DOI 10.1016/j.dnarep.2008.11.011, PubMed 19071233

Solberg N, Machon O, Krauss S (2008)
Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool
Dev Dyn, 237 (7), 1799-811
DOI 10.1002/dvdy.21586, PubMed 18521945

Publications 2007

Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL (2007)
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling
Cereb Cortex, 18 (9), 2117-31
DOI 10.1093/cercor/bhm238, PubMed 18165280

Hildrestrand GA, Diep DB, Kunke D, Bolstad N, Bjørås M, Krauss S, Luna L (2007)
The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
DNA Repair (Amst), 6 (6), 723-32
DOI 10.1016/j.dnarep.2006.12.008, PubMed 17236821

Kreslova J, Machon O, Ruzickova J, Lachova J, Wawrousek EF, Kemler R, Krauss S, Piatigorsky J, Kozmik Z (2007)
Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function
Genesis, 45 (4), 157-68
DOI 10.1002/dvg.20277, PubMed 17410548

Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S (2007)
A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus
Dev Biol, 311 (1), 223-37
DOI 10.1016/j.ydbio.2007.08.038, PubMed 17916349

Publications 2006

Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z (2006)
Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
J Biol Chem, 282 (2), 1225-37
DOI 10.1074/jbc.M605851200, PubMed 17090534

Kadowaki M, Nakamura S, Machon O, Krauss S, Radice GL, Takeichi M (2006)
N-cadherin mediates cortical organization in the mouse brain
Dev Biol, 304 (1), 22-33
DOI 10.1016/j.ydbio.2006.12.014, PubMed 17222817

Publications 2005

Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S (2005)
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon
Dev Biol, 279 (1), 155-68
DOI 10.1016/j.ydbio.2004.12.010, PubMed 15708565

Lorico A, Bratbak D, Meyer J, Kunke D, Krauss S, Plott WE, Solodushko V, Baum C, Fodstad O, Rappa G (2005)
Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells
Hum Gene Ther, 16 (6), 711-24
DOI 10.1089/hum.2005.16.711, PubMed 15960602

Machon O, Backman M, Krauss S, Kozmik Z (2005)
The cellular fate of cortical progenitors is not maintained in neurosphere cultures
Mol Cell Neurosci, 30 (3), 388-97
DOI 10.1016/j.mcn.2005.08.003, PubMed 16150605

Olsen PA, Randol M, Krauss S (2005)
Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides
Gene Ther, 12 (6), 546-51
DOI 10.1038/sj.gt.3302454, PubMed 15674399

Olsen PA, Randøl M, Luna L, Brown T, Krauss S (2005)
Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends
J Gene Med, 7 (12), 1534-44
DOI 10.1002/jgm.804, PubMed 16025558

Publications 2004

Diep DB, Hoen N, Backman M, Machon O, Krauss S (2004)
Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain
Brain Res Dev Brain Res, 153 (2), 261-70
DOI 10.1016/j.devbrainres.2004.09.008, PubMed 15527894

Petersen PH, Zou K, Krauss S, Zhong W (2004)
Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
Nat Neurosci, 7 (8), 803-11
DOI 10.1038/nn1289, PubMed 15273690

Rappa G, Kunke D, Holter J, Diep DB, Meyer J, Baum C, Fodstad O, Krauss S, Lorico A (2004)
Efficient expansion and gene transduction of mouse neural stem/progenitor cells on recombinant fibronectin
Neuroscience, 124 (4), 823-30
DOI 10.1016/j.neuroscience.2003.11.030, PubMed 15026123

Publications 2003

Backman M, Machon O, Van Den Bout CJ, Krauss S (2003)
Targeted disruption of mouse Dach1 results in postnatal lethality
Dev Dyn, 226 (1), 139-44
DOI 10.1002/dvdy.10210, PubMed 12508235

Machon O, van den Bout CJ, Backman M, Kemler R, Krauss S (2003)
Role of beta-catenin in the developing cortical and hippocampal neuroepithelium
Neuroscience, 122 (1), 129-43
DOI 10.1016/s0306-4522(03)00519-0, PubMed 14596855

Olsen PA, McKeen C, Krauss S (2003)
Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter
Gene Ther, 10 (21), 1830-40
DOI 10.1038/sj.gt.3302079, PubMed 12960973

Publications 2002

Machon O, van den Bout CJ, Backman M, Røsok Ø, Caubit X, Fromm SH, Geronimo B, Krauss S (2002)
Forebrain-specific promoter/enhancer D6 derived from the mouse Dach1 gene controls expression in neural stem cells
Neuroscience, 112 (4), 951-66
DOI 10.1016/s0306-4522(02)00053-2, PubMed 12088753

van den Bout CJ, Machon O, Røsok Ø, Backman M, Krauss S (2002)
The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus
Mech Dev, 110 (1-2), 179-82
DOI 10.1016/s0925-4773(01)00597-4, PubMed 11744379

Publications 2000

Machon O, Backman M, Julin K, Krauss S (2000)
Yeast two-hybrid system identifies the ubiquitin-conjugating enzyme mUbc9 as a potential partner of mouse Dac
Mech Dev, 97 (1-2), 3-12
DOI 10.1016/s0925-4773(00)00402-0, PubMed 11025202

Publications 1999

Caubit X, Thangarajah R, Theil T, Wirth J, Nothwang HG, Rüther U, Krauss S (1999)
Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud
Dev Dyn, 214 (1), 66-80
DOI 10.1002/(SICI)1097-0177(199901)214:1<66::AID-DVDY7>3.0.CO;2-7, PubMed 9915577

Shadidy M, Caubit X, Olsen R, Seternes OM, Moens U, Krauss S (1999)
Biochemical analysis of mouse FKBP60, a novel member of the FKPB family
Biochim Biophys Acta, 1446 (3), 295-307
DOI 10.1016/s0167-4781(99)00080-9, PubMed 10524204

Publications 1998

Delghandi M, Utsi E, Krauss S (1998)
Saami mitochondrial DNA reveals deep maternal lineage clusters
Hum Hered, 48 (2), 108-14
DOI 10.1159/000022789, PubMed 9526170

Nornes S, Clarkson M, Mikkola I, Pedersen M, Bardsley A, Martinez JP, Krauss S, Johansen T (1998)
Zebrafish contains two pax6 genes involved in eye development
Mech Dev, 77 (2), 185-96
DOI 10.1016/s0925-4773(98)00156-7, PubMed 9831649

Publications 1997

Martínez-Barberá JP, Toresson H, Da Rocha S, Krauss S (1997)
Cloning and expression of three members of the zebrafish Bmp family: Bmp2a, Bmp2b and Bmp4
Gene, 198 (1-2), 53-9
DOI 10.1016/s0378-1119(97)00292-8, PubMed 9370264

Publications 1996

Nornes S, Mikkola I, Krauss S, Delghandi M, Perander M, Johansen T (1996)
Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences
J Biol Chem, 271 (43), 26914-23
DOI 10.1074/jbc.271.43.26914, PubMed 8900176

Publications 1994

Macdonald R, Xu Q, Barth KA, Mikkola I, Holder N, Fjose A, Krauss S, Wilson SW (1994)
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain
Neuron, 13 (5), 1039-53
DOI 10.1016/0896-6273(94)90044-2, PubMed 7946344

Nordnes S, Krauss S, Johansen T (1994)
cDNA sequence of zebrafish (Brachydanio rerio) translation elongation factor-1 alpha: molecular phylogeny of eukaryotes based on elongation factor-1 alpha protein sequences
Biochim Biophys Acta, 1219 (2), 529-32
DOI 10.1016/0167-4781(94)90081-7, PubMed 7918652

Publications 1993

Ericson JU, Krauss S, Fjose A (1993)
Genomic sequence and embryonic expression of the zebrafish homeobox gene hox-3.4
Int J Dev Biol, 37 (2), 263-72
PubMed 8104460

Johansen T, Moens U, Holm T, Fjose A, Krauss S (1993)
Zebrafish pou[c]: a divergent POU family gene ubiquitously expressed during embryogenesis
Nucleic Acids Res, 21 (3), 475-83
DOI 10.1093/nar/21.3.475, PubMed 8441661

Publications 1992

Fjose A, Njølstad PR, Nornes S, Molven A, Krauss S (1992)
Structure and early embryonic expression of the zebrafish engrailed-2 gene
Mech Dev, 39 (1-2), 51-62
DOI 10.1016/0925-4773(92)90025-f, PubMed 1362650

Krauss S, Korzh V, Fjose A, Johansen T (1992)
Expression of four zebrafish wnt-related genes during embryogenesis
Development, 116 (1), 249-59
DOI 10.1242/dev.116.1.249, PubMed 1483391

Mikkola I, Fjose A, Kuwada JY, Wilson S, Guddal PH, Krauss S (1992)
The paired domain-containing nuclear factor pax[b] is expressed in specific commissural interneurons in zebrafish embryos
J Neurobiol, 23 (8), 933-46
DOI 10.1002/neu.480230802, PubMed 1361000

Publications 1991

Krauss S, Johansen T, Korzh V, Fjose A (1991)
Expression pattern of zebrafish pax genes suggests a role in early brain regionalization
Nature, 353 (6341), 267-70
DOI 10.1038/353267a0, PubMed 1680220

Krauss S, Johansen T, Korzh V, Fjose A (1991)
Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis
Development, 113 (4), 1193-206
DOI 10.1242/dev.113.4.1193, PubMed 1811936

Krauss S, Johansen T, Korzh V, Moens U, Ericson JU, Fjose A (1991)
Zebrafish pax[zf-a]: a paired box-containing gene expressed in the neural tube
EMBO J, 10 (12), 3609-19
DOI 10.1002/j.1460-2075.1991.tb04927.x, PubMed 1718739