Maria Vistnes

  • Senior Cardiologist; MD, PhD
  • +47 95 87 51 14

Mini CV

  • Senior Cardiologist, Postdoctoral researcher, MD, PhD
  • +47 95 87 51 14
  • maria.vistnes@medisin.uio.no

Education

  • Certified specialist in Cardiology (2023)
  • PhD, Faculty of Medicine, University of Oslo (2012)
  • MD, University of Oslo (2010)

Work record (selected)

  • Consultant Cardiologist, Cardiology Department, Oslo University Hospital Ullevål (2023 – present)
  • Postdoctoral candidate, Cardiology Department, Oslo University Hospital Ullevål (2023 - present)
  • Postdoctoral candidate, Institute for Experimental Medical Research, Oslo University Hospital (2018 – 2023)
  • Researcher, Institute for Experimental Medical Research, Oslo University Hospital (2015 – 2018)
  • Resident in Internal Medicine and Cardiology, Diakonhjemmet Hospital (2013 - 2018)

Awards, committees, memberships

  • SPARK innovation program, University of Oslo (2019-2022)
  • Working Group for heart failure, Norwegian Society of Cardiology (2021 – present)
  • Quality Panel for assessment of ESC guidelines on heart failure (2021 and 2023)

Other

  • Main supervisor for PhD student Simon Andrup, Faculty of Medicine, University of Oslo (2020 – present) 
  • Co-supervisor for PhD student Athiramol Sasi, Faculty of Medicine, University of Oslo (2019 – present)

Research Areas 

  • Heart failure mechanisms, in particular extracellular matrix and fibrosis
  • Quantification of biomarkers, including new methods and assay development
  • Innovation and commercialization, development of new therapies
  • Remote patient monitoring (“Digital hjemmeoppfølging”) 
 

Publications 2024

Andrup S, Andersen GØ, Hoffmann P, Eritsland J, Seljeflot I, Halvorsen S, Vistnes M (2024)
Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality
PLoS One, 19 (5), e0302732
DOI 10.1371/journal.pone.0302732, PubMed 38739599

Thorlacius EM, Keski-Nisula J, Vistnes M, Ojala T, Molin M, Synnergren M, Romlin BS, Ricksten SE, Wåhlander H, Castellheim AG (2024)
High-sensitive troponinT, interleukin-8, and interleukin-6 link with post-surgery risk in infant heart surgery
Acta Anaesthesiol Scand (in press)
DOI 10.1111/aas.14405, PubMed 38531618

Vistnes M (2024)
Survival of the strongest: can muscular strength measurements be used in prevention of heart failure in patients with acute coronary syndromes?
Eur J Prev Cardiol, 31 (7), 832-833
DOI 10.1093/eurjpc/zwae047, PubMed 38381591

Vistnes M (2024)
Hitting the Target! Challenges and Opportunities for TGF-β Inhibition for the Treatment of Cardiac fibrosis
Pharmaceuticals (Basel), 17 (3)
DOI 10.3390/ph17030267, PubMed 38543053

Publications 2023

Sasi A, Romaine A, Erusappan PM, Melleby AO, Hasic A, Dahl CP, Broch K, Almaas VM, Puertas RD, Roderick HL, Lunde IG, Sjaastad I, Vistnes M, Christensen G (2023)
Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development
Matrix Biol Plus, 19-20, 100135
DOI 10.1016/j.mbplus.2023.100135, PubMed 38076279

Vistnes M (2023)
How can we improve the follow-up of patients with heart failure?
Tidsskr Nor Laegeforen, 143 (17)
DOI 10.4045/tidsskr.23.0735, PubMed 37987060

Vistnes M, Erusappan PM, Sasi A, Nordén ES, Bergo KK, Romaine A, Lunde IG, Zhang L, Olsen MB, Øgaard J, Carlson CR, Wang CH, Riise J, Dahl CP, Fiane AE, Hauge-Iversen IM, Espe E, Melleby AO, Tønnessen T, Aronsen JM, Sjaastad I, Christensen G (2023)
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909

Publications 2022

Gløersen M, Steen Pettersen P, Neogi T, Jafarzadeh SR, Vistnes M, Thudium CS, Bay-Jensen AC, Sexton J, Kvien TK, Hammer HB, Haugen IK (2022)
Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis
Arthritis Rheumatol, 74 (5), 810-817
DOI 10.1002/art.42056, PubMed 35137553

Publications 2021

Thorlacius EM, Vistnes M, Ojala T, Keski-Nisula J, Molin M, Romlin BS, Synnergren M, Ricksten SE, Wåhlander H, Castellheim A (2021)
Levosimendan Versus Milrinone and Release of Myocardial Biomarkers After Pediatric Cardiac Surgery: Post Hoc Analysis of Clinical Trial Data
Pediatr Crit Care Med, 22 (7), e402-e409
DOI 10.1097/PCC.0000000000002712, PubMed 33739957

Publications 2020

Hazen J, Vistnes M, Barca ML, Eldholm RS, Persson K, Brækhus A, Saltvedt I, Selbæk G, Engedal K, Knapskog AB (2020)
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
Alzheimer Dis Assoc Disord, 34 (1), 47-53
DOI 10.1097/WAD.0000000000000342, PubMed 31414991

Hetland A, Vistnes M, Haugaa KH, Liland KH, Olseng M, Edvardsen T (2020)
Obstructive sleep apnea versus central sleep apnea: prognosis in systolic heart failure
Cardiovasc Diagn Ther, 10 (3), 396-404
DOI 10.21037/cdt.2020.03.02, PubMed 32695620

Krogstad V, Peric A, Robertsen I, Kringen MK, Vistnes M, Hjelmesæth J, Sandbu R, Johnson LK, Angeles PC, Jansson-Löfmark R, Karlsson C, Andersson S, Åsberg A, Andersson TB, Christensen H (2020)
Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes
J Pharm Sci, 110 (1), 432-437
DOI 10.1016/j.xphs.2020.10.027, PubMed 33091408

Publications 2019

Kononova N, Sikkeland LIB, Mahmood F, Vistnes M, Kongerud J, Einvik G, Søyseth V (2019)
Annual decline in forced expiratory volume and airway inflammatory cells and mediators in a general population-based sample
BMC Pulm Med, 19 (1), 90
DOI 10.1186/s12890-018-0765-7, PubMed 31072364

Thorlacius EM, Suominen PK, Wåhlander H, Keski-Nisula J, Vistnes M, Ricksten SE, Synnergren M, Romlin BS, Castellheim A (2019)
The Effect of Levosimendan Versus Milrinone on the Occurrence Rate of Acute Kidney Injury Following Congenital Heart Surgery in Infants: A Randomized Clinical Trial
Pediatr Crit Care Med, 20 (10), 947-956
DOI 10.1097/PCC.0000000000002017, PubMed 31274775

Publications 2018

Wollmann BM, Syversen SW, Vistnes M, Lie E, Mehus LL, Molden E (2018)
Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis
Drug Metab Dispos, 46 (10), 1384-1389
DOI 10.1124/dmd.118.082065, PubMed 29991576

Publications 2017

Vistnes M, Tapia G, Mårild K, Midttun Ø, Ueland PM, Viken MK, Magnus P, Berg JP, Gillespie KM, Skrivarhaug T, Njølstad PR, Joner G, Størdal K, Stene LC (2017)
Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes
Am J Reprod Immunol, 79 (3)
DOI 10.1111/aji.12802, PubMed 29266506

Publications 2016

Hetland A, Haugaa KH, Vistnes M, Liland KH, Olseng M, Jacobsen MB, Edvardsen T (2016)
A retrospective analysis of cardiovascular outcomes in patients treated with ASV
Scand Cardiovasc J, 51 (2), 106-113
DOI 10.1080/14017431.2016.1262546, PubMed 27854123

Mårild K, Vistnes M, Tapia G, Midttun Ø, Ueland PM, Viken MK, Magnus P, Berg JP, Stene LC, Størdal K (2016)
Midpregnancy and cord blood immunologic biomarkers, HLA genotype, and pediatric celiac disease
J Allergy Clin Immunol, 139 (5), 1696-1698
DOI 10.1016/j.jaci.2016.10.016, PubMed 27865861

Publications 2014

Sanner H, Schwartz T, Flatø B, Vistnes M, Christensen G, Sjaastad I (2014)
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150

Schwartz T, Sjaastad I, Flatø B, Vistnes M, Christensen G, Sanner H (2014)
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906

Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621, PubMed 24595230

Publications 2013

Strand ME, Herum KM, Rana ZA, Skrbic B, Askevold ET, Dahl CP, Vistnes M, Hasic A, Kvaløy H, Sjaastad I, Carlson CR, Tønnessen T, Gullestad L, Christensen G, Lunde IG (2013)
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J, 280 (10), 2228-47
DOI 10.1111/febs.12161, PubMed 23374111

Publications 2012

Einvik G, Vistnes M, Hrubos-Strøm H, Randby A, Namtvedt SK, Nordhus IH, Somers VK, Dammen T, Omland T (2012)
Circulating cytokine concentrations are not associated with major depressive disorder in a community-based cohort
Gen Hosp Psychiatry, 34 (3), 262-7
DOI 10.1016/j.genhosppsych.2012.01.017, PubMed 22401706

Vistnes M (2012)
Macrophage inflammatory protein-1β: a novel prognostic biomarker in atherosclerosis?
Cardiology, 121 (3), 149-51
DOI 10.1159/000336484, PubMed 22441313

Waehre A, Vistnes M, Sjaastad I, Nygård S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433

Publications 2010

Vistnes M, Christensen G, Omland T (2010)
Multiple cytokine biomarkers in heart failure
Expert Rev Mol Diagn, 10 (2), 147-57
DOI 10.1586/erm.10.3, PubMed 20214534

Vistnes M, Waehre A, Nygård S, Sjaastad I, Andersson KB, Husberg C, Christensen G (2010)
Circulating cytokine levels in mice with heart failure are etiology dependent
J Appl Physiol (1985), 108 (5), 1357-64
DOI 10.1152/japplphysiol.01084.2009, PubMed 20224000

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