Jørgen A. Gravning
- Senior Cardiologist, Associate Professor; MD, PhD
- +47 950 75 310
More information from UiO home page
Education:
- 2005: M.D. (Cand. Med.), Faculty of Medicine, University of Oslo
- 2013: Ph.D., Faculty of Medicine, University of Oslo, Norway. Thesis: “Cardioprotective Mechanisms in Ischemia-Reperfusion Injury and Heart Failure”
- 2016: Board certified in Internal Medicine
- 2018: Board certified in Cardiology
Work record (selected)
- 2016-t.d.: Senior Consultant, Dept. of Cardiology, Oslo University Hospital, Ullevål,
- 2021-t.d.: Associate Professor, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo
- 2019-2021: Head of section for Resident Fellows, Dept. of Cardiology, Oslo University Hospital, Ullevål
- 2008-2016: Resident Fellow, Østfold Hospital Trust and Akershus University Hospital
- 2005-2008: Ph.D. Fellow, Institute for Surgical Research / Dept. of Cardiology, Oslo University Hospital, Rikshospitalet
Memberships:
- The Norwegian Medical Association
- Norwegian Society of Cardiology
- American Health Association
- European Society of Cardiology
Research areas:
- Cardiac imaging
- Cardiac biomarkers
- Cardiovascular heamodynamics
- Translational cardiovascular research
Teaching:
- Lecturer in clinical cardiology for medical Students at University of Oslo
Other:
- Author of the popular science book “Ditt fantastiske hjerte” (H. Aschehoug & co 2018)
Publications 2021
Re-appraisal of the obesity paradox in heart failure: a meta-analysis of individual data
Clin Res Cardiol, 110 (8), 1280-1291
DOI 10.1007/s00392-021-01822-1, PubMed 33704552
Publications 2019
Revisiting the obesity paradox in heart failure: Per cent body fat as predictor of biomarkers and outcome
Eur J Prev Cardiol, 26 (16), 1751-1759
DOI 10.1177/2047487319852809, PubMed 31154828
Mechanical dispersion as a marker of left ventricular dysfunction and prognosis in stable coronary artery disease
Int J Cardiovasc Imaging, 35 (7), 1265-1275
DOI 10.1007/s10554-019-01583-z, PubMed 31165941
Publications 2018
Prognostic Value of High-Sensitivity Troponin T in Chronic Heart Failure: An Individual Patient Data Meta-Analysis
Circulation, 137 (3), 286-297
DOI 10.1161/CIRCULATIONAHA.117.031560, PubMed 29335288
High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure
Int J Cardiol, 277, 166-172
DOI 10.1016/j.ijcard.2018.10.079, PubMed 30416028
sST2 Predicts Outcome in Chronic Heart Failure Beyond NT-proBNP and High-Sensitivity Troponin T
J Am Coll Cardiol, 72 (19), 2309-2320
DOI 10.1016/j.jacc.2018.08.2165, PubMed 30384887
Publications 2017
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Acta Bioquim. Clin. Latinoam., 51 (3), 395-407
Limited Added Value of Circulating Inflammatory Biomarkers in Chronic Heart Failure
JACC Heart Fail, 5 (4), 256-264
DOI 10.1016/j.jchf.2017.01.008, PubMed 28359413
Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans
Scand J Clin Lab Invest, 77 (5), 321-331
DOI 10.1080/00365513.2017.1318447, PubMed 28460577
Publications 2016
High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis
Clin Chem, 63 (2), 552-562
DOI 10.1373/clinchem.2016.261107, PubMed 27974383
Publications 2015
Sensitive cardiac troponins and N-terminal pro-B-type natriuretic peptide in stable coronary artery disease: correlation with left ventricular function as assessed by myocardial strain
Int J Cardiovasc Imaging, 31 (5), 967-73
DOI 10.1007/s10554-015-0646-6, PubMed 25788439
Publications 2013
Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes
Mol Pharmacol, 84 (3), 372-83
DOI 10.1124/mol.113.087312, PubMed 23778361
CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload
Int J Cardiol, 168 (3), 2049-56
DOI 10.1016/j.ijcard.2013.01.165, PubMed 23452880
Prognostic effect of high-sensitive troponin T assessment in elderly patients with chronic heart failure: results from the CORONA trial
Circ Heart Fail, 7 (1), 96-103
DOI 10.1161/CIRCHEARTFAILURE.113.000450, PubMed 24284025
Sensitive troponin assays and N-terminal pro-B-type natriuretic peptide in acute coronary syndrome: prediction of significant coronary lesions and long-term prognosis
Am Heart J, 165 (5), 716-24
DOI 10.1016/j.ahj.2013.02.008, PubMed 23622908
Publications 2012
Soluble glycoprotein 130 predicts fatal outcomes in chronic heart failure: analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Circ Heart Fail, 6 (1), 91-8
DOI 10.1161/CIRCHEARTFAILURE.112.972653, PubMed 23230311
Protecting the heart through delivering DNA encoding for heme oxygenase-1 into skeletal muscle
Life Sci, 91 (17-18), 828-36
DOI 10.1016/j.lfs.2012.08.014, PubMed 22917518
Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction
PLoS One, 7 (12), e52120
DOI 10.1371/journal.pone.0052120, PubMed 23284892
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload
Am J Physiol Heart Circ Physiol, 303 (1), H66-74
DOI 10.1152/ajpheart.00724.2011, PubMed 22542621
Publications 2011
Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo
Life Sci, 88 (11-12), 543-50
DOI 10.1016/j.lfs.2011.01.006, PubMed 21238463
Publications 2010
Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol, 300 (4), H1291-302
DOI 10.1152/ajpheart.00604.2010, PubMed 21186275
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
DOI 10.1186/1471-2407-10-6, PubMed 20053285
Publications 2008
The perfect biomarker in acute coronary syndrome: a challenge for diagnosis, prognosis, and treatment
Eur Heart J, 29 (23), 2827-8
DOI 10.1093/eurheartj/ehn489, PubMed 18957473
Different prognostic importance of elevated troponin I after percutaneous coronary intervention in acute coronary syndrome and stable angina pectoris
Scand Cardiovasc J, 42 (3), 214-21
DOI 10.1080/14017430801932824, PubMed 18569954
Publications 2007
Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 Uncovers Distinct Functions of GRK3 in regulation of cardiac contractility and growth: GRK3 controls cardiac alpha1-adrenergic receptor responsiveness
J Biol Chem, 283 (16), 10601-10
DOI 10.1074/jbc.M708912200, PubMed 18165681
Publications 2006
[Unexpected sudden death after percutaneous coronary intervention]
Tidsskr Nor Laegeforen, 126 (16), 2111-3
PubMed 16960998