Publications 2024

Alirezaylavasani A, Skeie LG, Egner IM, Chopra A, Dahl TB, Prebensen C, Vaage JT, Halvorsen B, Lund-Johansen F, Tonby K, Reikvam DH, Stiksrud B, Holter JC, Dyrhol-Riise AM, Munthe LA, Kared H (2024)
Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
NPJ Vaccines, 9 (1), 185
DOI 10.1038/s41541-024-00972-3, PubMed 39384763

Barratt-Due A, Pettersen K, Børresdatter-Dahl T, Holter JC, Grønli RH, Dyrhol-Riise AM, Lerum TV, Holten AR, Tonby K, Trøseid M, Skjønsberg OH, Granerud BK, Heggelund L, Kildal AB, Schjalm C, Aaløkken TM, Aukrust P, Ueland T, Mollnes TE, Halvorsen B, NOR‐Solidarity study groupThe Norwegian SARS‐CoV‐2 study group (2024)
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241

Grannes H, Ueland T, Simeone P, Liani R, Guagnano MT, Aukrust P, Michelsen AE, Birkeland K, di Castelnuovo A, Cipollone F, Consoli A, Halvorsen B, Gregersen I, Santilli F (2024)
Liraglutide and not lifestyle intervention reduces soluble CD163 after comparable weight loss in obese participants with prediabetes or type 2 diabetes mellitus
Cardiovasc Diabetol, 23 (1), 146
DOI 10.1186/s12933-024-02237-8, PubMed 38685051

Gregersen I, Kong XY, Kooijman S, Foyn H, Grannes H, Olsen MB, Lone AM, Yang K, Quiles-Jiménez A, Tran M, Øgaard J, Segers FM, Rashidi A, Sagen EL, Lauritzen KH, Pronk ACM, de Boer JF, Holven KB, Melum E, Aukrust P, Taskén K, Holm S, Rensen PCN, Dahl TB, Halvorsen B (2024)
T cells with increased responsiveness cause obesity in mice without diet intervention
iScience, 27 (4), 109471
DOI 10.1016/j.isci.2024.109471, PubMed 38551005

Gregersen I, Narverud I, Christensen JJ, Hovland A, Øyri LKL, Ueland T, Retterstøl K, Bogsrud MP, Aukrust P, Halvorsen B, Holven KB (2024)
Plasma legumain in familial hypercholesterolemia: associations with statin use and cardiovascular risk markers
Scand J Clin Lab Invest, 84 (1), 24-29
DOI 10.1080/00365513.2024.2309617, PubMed 38319290

Gregersen I, Scarth ME, Abdullah R, Thorsby PM, Hauger LE, Haugaa KH, Sagen EL, Michelsen AE, Ueland T, Edvardsen T, Aukrust P, Almaas VM, Bjørnebekk AK, Halvorsen B (2024)
Elevated interleukin 8 and matrix metalloproteinase 9 levels are associated with myocardial pathology in users of anabolic-androgenic steroids
Eur J Prev Cardiol, 31 (12), 1469-1476
DOI 10.1093/eurjpc/zwae126, PubMed 38573232

Halvorsen B, Viermyr HK, Ueland T, Sagen EL, Michelsen AE, Bjerkeli V, Nor-Solidarity Study Group, Tveita AA, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Trøseid M, Dahl TB, Aukrust P, Gregersen I (2024)
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108

Holm S, Michelsen AE, Schultz NH, Ueland T, Reikvam H, Holme PA, Aukrust P, Halvorsen B (2024)
Human papilloma virus vaccine induced thrombocytopenia accompanied by a wide spectrum of reversible inflammatory responses - a case report
Scand J Clin Lab Invest, 84 (6), 425-427
DOI 10.1080/00365513.2024.2400663, PubMed 39264796

Holme FA, Huse C, Kong XY, Broch K, Gullestad L, Anstensrud AK, Andersen GØ, Amundsen BH, Kleveland O, Quiles-Jimenez A, Holm S, Aukrust P, Alseth I, Halvorsen B, Dahl TB (2024)
Circular RNA Profile in Atherosclerotic Disease: Regulation during ST-Elevated Myocardial Infarction
Int J Mol Sci, 25 (16)
DOI 10.3390/ijms25169014, PubMed 39201700

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714

Kindberg KM, Broch K, Andersen GØ, Anstensrud AK, Åkra S, Woxholt S, Tøllefsen IM, Ueland T, Amundsen BH, Kløw NE, Halvorsen B, Dahl TB, Huse C, Murphy SL, Damås JK, Opdahl A, Wiseth R, Gullestad L, Aukrust P, Santos-Gallego C, Seljeflot I, Stokke MK, Helseth R (2024)
Neutrophil Extracellular Traps in ST-Segment Elevation Myocardial Infarction: Reduced by Tocilizumab and Associated With Infarct Size
JACC Adv, 3 (9), 101193
DOI 10.1016/j.jacadv.2024.101193, PubMed 39247678

Kong XY, Lauritzen KH, Dahl TB, Holm S, Olsen MB, Skjelland M, Nielsen C, Michelsen AE, Ueland T, Aukrust P, Halvorsen B, Sandanger Ø (2024)
CD38 deficient mice are not protected from atherosclerosis
Biochem Biophys Res Commun, 705, 149734
DOI 10.1016/j.bbrc.2024.149734, PubMed 38430607

Løvheim EB, Retterstøl K, Narverud I, Bogsrud MP, Halvorsen B, Ueland T, Aukrust P, Holven KB (2024)
Adherence to the Healthy Nordic Food Index is associated with reduced plasma levels of inflammatory markers in patients with heterozygous familial hypercholesterolemia
Atheroscler Plus, 58, 38-45
DOI 10.1016/j.athplu.2024.10.003, PubMed 39525275

Melnes T, Bogsrud MP, Christensen JJ, Rundblad A, Narverud I, Retterstøl K, Aukrust P, Halvorsen B, Ulven SM, Holven KB (2024)
Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Atherosclerosis, 392, 117507
DOI 10.1016/j.atherosclerosis.2024.117507, PubMed 38663317

Murphy SL, Balzer NR, Ranheim T, Sagen EL, Huse C, Bjerkeli V, Michelsen AE, Finbråten AK, Heggelund L, Dyrhol-Riise AM, Tveita A, Holten AR, Trøseid M, Ueland T, Ulas T, Aukrust P, Barratt-Due A, Halvorsen B, Dahl TB (2024)
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465

Olsen MB, Kong XY, Louwe MC, Lauritzen KH, Schanke Y, Kaasbøll OJ, Attramadal H, Øgaard J, Holm S, Aukrust P, Ryan L, Espevik T, Yurchenko M, Halvorsen B (2024)
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice
Front Immunol, 15, 1383505
DOI 10.3389/fimmu.2024.1383505, PubMed 38686379

Olsen MB, Louwe MC, Yang K, Øgaard J, Dahl TB, Gregersen I, Alfsnes K, Lauritzen KH, Murphy SL, Ahmed MS, Aukrust P, Vinge LE, Yndestad A, Holven KB, Halvorsen B, Fosshaug LE (2024)
Continuous infusion of resolvin D2 in combination with Angiotensin-II show contrary effects on blood pressure and intracardiac artery remodeling
Biochem Biophys Res Commun, 733, 150706
DOI 10.1016/j.bbrc.2024.150706, PubMed 39305571

Raju SC, Molinaro A, Awoyemi A, Jørgensen SF, Braadland PR, Nendl A, Seljeflot I, Ueland PM, McCann A, Aukrust P, Vestad B, Mayerhofer C, Broch K, Gullestad L, Lappegård KT, Halvorsen B, Kristiansen K, Hov JR, Trøseid M (2024)
Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
Genome Med, 16 (1), 27
DOI 10.1186/s13073-024-01296-6, PubMed 38331891

Udjus C, Halvorsen B, Kong XY, Sagen EL, Martinsen M, Yang K, Løberg EM, Christensen G, Skjønsberg OH, Larsen KO (2024)
Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs
Physiol Rep, 12 (14), e16143
DOI 10.14814/phy2.16143, PubMed 39034131

Viermyr HK, Halvorsen B, Sagen EL, Michelsen AE, Barrat-Due A, Kåsine T, Nezvalova-Henriksen K, Dyrhol-Riise AM, Nor‐Solidarity Consortium, Lerum TV, Müller F, Tonby K, Tveita A, Aukrust P, Trøseid M, Ueland T, Dahl TB (2024)
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800

Woxholt S, Ueland T, Aukrust P, Anstensrud AK, Broch K, Tøllefsen IM, Seljeflot I, Halvorsen B, Dahl TB, Huse C, Andersen GØ, Gullestad L, Wiseth R, Damås JK, Kleveland O (2024)
Effect of tocilizumab on endothelial and platelet-derived CXC-chemokines and their association with inflammation and myocardial injury in STEMI patients undergoing primary PCI
Int J Cardiol, 418, 132613 (in press)
DOI 10.1016/j.ijcard.2024.132613, PubMed 39374793

Yang M, Kaarbø M, Myhre V, Reims HM, Karlsen TH, Wang J, Rognes T, Halvorsen B, Fevang B, Lundin KEA, Aukrust P, Bjørås M, Jørgensen SF (2024)
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
J Clin Immunol, 44 (6), 133
DOI 10.1007/s10875-024-01726-5, PubMed 38780872

Zamani M, Skagen K, Lindberg B, Bjerkeli V, Aukrust P, Halvorsen B, Skjelland M (2024)
Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study
Front Immunol, 15, 1385377
DOI 10.3389/fimmu.2024.1385377, PubMed 38711510

Publications 2023

Dahlberg D, Holm S, Sagen EML, Michelsen AE, Stensland M, de Souza GA, Müller EG, Connelly JP, Revheim ME, Halvorsen B, Hassel B (2023)
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989

Halvorsen B, Aukrust P, Dahl TB, Gregersen I (2023)
Increased cardiovascular mortality during the COVID-19 pandemic: do not neglect causality
Eur Heart J Open, 3 (6), oead119
DOI 10.1093/ehjopen/oead119, PubMed 38089856

Jorgensen SF, Macpherson ME, Skarpengland T, Berge RK, Fevang B, Halvorsen B, Aukrust P (2023)
Disturbed lipid profile in common variable immunodeficiency - a pathogenic loop of inflammation and metabolic disturbances
Front Immunol, 14, 1199727
DOI 10.3389/fimmu.2023.1199727, PubMed 37545531

Macpherson ME, Skarpengland T, Hov JR, Ranheim T, Vestad B, Dahl TB, Fraz MSA, Michelsen AE, Holven KB, Fevang B, Berge RK, Aukrust P, Halvorsen B, Jørgensen SF (2023)
Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
J Clin Immunol, 43 (6), 1229-1240
DOI 10.1007/s10875-023-01475-x, PubMed 36995502

Murphy SL, Halvorsen B, Holter JC, Huse C, Tveita A, Trøseid M, Hoel H, Kildal AB, Holten AR, Lerum TV, Skjønsberg OH, Michelsen AE, Aaløkken TM, NOR-SOLIDARITY Consortium, The Norwegian SARS-CoV-2 study group investigators, Tonby K, Lind A, Dudman S, Granerud BK, Heggelund L, Bøe S, Dyrholt-Riise AM, Aukrust P, Barratt-Due A, Ueland T, Dahl TB (2023)
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572

Nendl A, Raju SC, Broch K, Mayerhofer CCK, Holm K, Halvorsen B, Lappegård KT, Moscavitch S, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2023)
Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
Front Cardiovasc Med, 10, 1160030
DOI 10.3389/fcvm.2023.1160030, PubMed 37332580

Quiles-Jiménez A, Sousa MML, Huse C, Dyrhol-Riise AM, Holter JC, Christensen EE, Tonby K, Holten AR, Aukrust P, Bjørås M, Dahl TB, Halvorsen B (2023)
Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome
J Infect, 86 (6), 593-595
DOI 10.1016/j.jinf.2023.03.002, PubMed 36889510

Ratajczak-Tretel B, Lambert AT, Al-Ani R, Arntzen K, Bakkejord GK, Bekkeseth HMO, Bjerkeli V, Eldøen G, Gulsvik AK, Halvorsen B, Høie GA, Ihle-Hansen H, Ihle-Hansen H, Ingebrigtsen S, Kremer C, Krogseth SB, Kruuse C, Kurz M, Nakstad I, Novotny V, Næss H, Qazi R, Rezaj MK, Rørholt DM, Steffensen LH et al. (2023)
Prediction of underlying atrial fibrillation in patients with a cryptogenic stroke: results from the NOR-FIB Study
J Neurol, 270 (8), 4049-4059
DOI 10.1007/s00415-023-11680-8, PubMed 37162578

Ratajczak-Tretel B, Lambert AT, Al-Ani R, Arntzen K, Bakkejord GK, Bekkeseth HMO, Bjerkeli V, Eldøen G, Gulsvik AK, Halvorsen B, Høie GA, Ihle-Hansen H, Ingebrigtsen S, Kremer C, Krogseth SB, Kruuse C, Kurz M, Nakstad I, Novotny V, Naess H, Qazi R, Rezaj MK, Rørholt DM, Steffensen LH, Sømark J et al. (2023)
Underlying causes of cryptogenic stroke and TIA in the nordic atrial fibrillation and stroke (NOR-FIB) study - the importance of comprehensive clinical evaluation
BMC Neurol, 23 (1), 115
DOI 10.1186/s12883-023-03155-0, PubMed 36944929

Segers FME, Ruder AV, Westra MM, Lammers T, Dadfar SM, Roemhild K, Lam TS, Kooi ME, Cleutjens KBJM, Verheyen FK, Schurink GWH, Haenen GR, van Berkel TJC, Bot I, Halvorsen B, Sluimer JC, Biessen EAL (2023)
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis
Cardiovasc Res, 118 (17), 3346-3359
DOI 10.1093/cvr/cvac032, PubMed 35325057

Stø K, Skagen KR, Valeur J, Yang K, Bjerkeli V, Aukrust P, Skjelland M, Halvorsen B (2023)
Increased plasma levels of non-sugar sweeteners in patients with symptomatic carotid atherosclerosis
Scand Cardiovasc J, 57 (1), 2205068
DOI 10.1080/14017431.2023.2205068, PubMed 37102258

Tancin Lambert A, Ratajczak-Tretel B, Al-Ani R, Arntzen K, Bakkejord GK, Bekkeseth HMO, Bjerkeli V, Eldøen G, Gulsvik AK, Halvorsen B, Høie GA, Ihle-Hansen H, Ihle-Hansen H, Ingebrigtsen S, Johansen H, Kremer C, Krogseth SB, Kruuse C, Kurz M, Nakstad I, Novotny V, Naess H, Qazi R, Rezai MK, Rørholt DM et al. (2023)
Biomarkers predictive of atrial fibrillation in patients with cryptogenic stroke. Insights from the Nordic Atrial Fibrillation and Stroke (NOR-FIB) study
Eur J Neurol, 30 (5), 1352-1363
DOI 10.1111/ene.15746, PubMed 36786305

Trøseid M, Arribas JR, Assoumou L, Holten AR, Poissy J, Terzić V, Mazzaferri F, Baño JR, Eustace J, Hites M, Joannidis M, Paiva JA, Reuter J, Püntmann I, Patrick-Brown TDJH, Westerheim E, Nezvalova-Henriksen K, Beniguel L, Dahl TB, Bouscambert M, Halanova M, Péterfi Z, Tsiodras S, Rezek M, Briel M et al. (2023)
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655

Ueland T, Michelsen AE, Tveita AA, Kåsine T, Dahl TB, Finbråten AK, Holten AR, Skjønsberg OH, Mathiessen A, Henriksen KN, Trøseid M, Aaløkken TM, Halvorsen B, Dyrhol-Riise AM, Barratt-Due A, Aukrust P (2023)
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350

Ueland T, Äikäs LAO, Dahl TB, Gregersen I, Olsen MB, Michelsen A, Schanke Y, Holopainen M, Ruhanen H, Singh S, NOR-SOLIDARITY Consortium, Tveita AA, Finbråten AK, Heggelund L, Trøseid M, Dyrhol-Riise AM, Nyman TA, Holven KB, Öörni K, Aukrust P, Halvorsen B (2023)
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413

Woxholt S, Ueland T, Aukrust P, Anstensrud AK, Broch K, Tøllefsen IM, Ryan L, Bendz B, Hopp E, Kløw NE, Seljeflot I, Halvorsen B, Dahl TB, Huse C, Andersen GØ, Gullestad L, Wiseth R, Amundsen BH, Damas JK, Kleveland O (2023)
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
Open Heart, 10 (2)
DOI 10.1136/openhrt-2023-002301, PubMed 37591633

Publications 2022

Berg J, Halvorsen AR, Bengtson MB, Lindberg M, Halvorsen B, Aukrust P, Helland Å, Ueland T (2022)
Circulating T Cell Activation and Exhaustion Markers Are Associated With Radiation Pneumonitis and Poor Survival in Non-Small-Cell Lung Cancer
Front Immunol, 13, 875152
DOI 10.3389/fimmu.2022.875152, PubMed 35911763

Berg J, Halvorsen AR, Bengtson MB, Lindberg M, Halvorsen B, Aukrust P, Helland Å, Ueland T (2022)
Corrigendum: Circulating T cell activation and exhaustion markers are associated with radiation pneumonitis and poor survival in non-small-cell lung cancer
Front Immunol, 13, 1051156
DOI 10.3389/fimmu.2022.1051156, PubMed 36263024

Bjørnebekk A, Scarth M, Neupane SP, Westlye LT, Hullstein IR, Thorsby PM, Halvorsen B (2022)
Use of High-Dose Androgens Is Associated with Reduced Brain-Derived Neurotrophic Factor in Male Weightlifters
Neuroendocrinology, 113 (1), 36-47
DOI 10.1159/000526418, PubMed 35944495

Carracedo S, Lirussi L, Alsøe L, Segers F, Wang C, Bartosova Z, Bohov P, Tekin NB, Kong XY, Esbensen QY, Chen L, Wennerström A, Kroustallaki P, Ceolotto D, Tönjes A, Berge RK, Bruheim P, Wong G, Böttcher Y, Halvorsen B, Nilsen H (2022)
SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice
DNA Repair (Amst), 120, 103410
DOI 10.1016/j.dnarep.2022.103410, PubMed 36244177

Fontaine MAC, Jin H, Gagliardi M, Rousch M, Wijnands E, Stoll M, Li X, Schurgers L, Reutelingsperger C, Schalkwijk C, van den Akker NMS, Molin DGM, Gullestad L, Eritsland J, Hoffman P, Skjelland M, Andersen GØ, Aukrust P, Karel J, Smirnov E, Halvorsen B, Temmerman L, Biessen EAL (2022)
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair
Adv Sci (Weinh), 10 (5), e2203053
DOI 10.1002/advs.202203053, PubMed 36526599

Granerud BK, Ueland T, Lind A, Søraas A, Fevang B, Steffensen AK, Al-Baldawi H, Lund-Johansen F, Aukrust P, Halvorsen B, Dahl TB, Dudman S, Müller F, Holter JC (2022)
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518

Gregersen I, Ueland T, Holter JC, Olsen MB, Michelsen AE, Murphy SL, Tveita AA, Henriksen KN, Hoel H, Nordberg LB, Holten AR, Edvardsen T, Yang K, Heggelund L, Trøseid M, Müller F, Kildal AB, Dyrhol-Riise AM, Barratt-Due A, Dahl TB, Aukrust P, Halvorsen B, NOR-SOLIDARITY consortium, The Norwegian SARS-CoV-2 Study Group investigators (2022)
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188

Hassel B, Niehusmann P, Halvorsen B, Dahlberg D (2022)
Pro-inflammatory cytokines in cystic glioblastoma: A quantitative study with a comparison with bacterial brain abscesses. With an MRI investigation of displacement and destruction of the brain tissue surrounding a glioblastoma
Front Oncol, 12, 846674
DOI 10.3389/fonc.2022.846674, PubMed 35965529

Huse C, Anstensrud AK, Michelsen AE, Ueland T, Broch K, Woxholt S, Yang K, Sharma K, Tøllefsen IM, Bendz B, Amundsen BH, Damås JK, Berg ES, Bjørkelund E, Quiles-Jiménez A, Bjerkeli V, Bendz C, Kleveland O, Stensaeth KH, Opdahl A, Kløw NE, Andersen GØ, Wiseth R, Halvorsen B, Gullestad L et al. (2022)
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178

Karlsen TR, Olsen MB, Kong XY, Yang K, Quiles-Jiménez A, Kroustallaki P, Holm S, Lines GT, Aukrust P, Skarpengland T, Bjørås M, Dahl TB, Nilsen H, Gregersen I, Halvorsen B (2022)
NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length
Biochem Biophys Rep, 29, 101211
DOI 10.1016/j.bbrep.2022.101211, PubMed 35079641

Kaarbø M, Yang M, Hov JR, Holm K, de Sousa MML, Macpherson ME, Reims HM, Kran AB, Halvorsen B, Karlsen TH, Aukrust P, Lundin KEA, Fevang B, Bjørås M, Jørgensen SF (2022)
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
J Allergy Clin Immunol, 151 (3), 767-777
DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400

Lee-Ødegård S, Ueland T, Thorsby PM, Aukrust P, Michelsen AE, Halvorsen B, Drevon CA, Birkeland KI (2022)
Fetuin-A mediates the difference in adipose tissue insulin resistance between young adult pakistani and norwegian patients with type 2 diabetes
BMC Endocr Disord, 22 (1), 208
DOI 10.1186/s12902-022-01127-y, PubMed 35978354

Lekva T, Ueland T, Halvorsen B, Murphy SL, Dyrhol-Riise AM, Tveita A, Finbråten AK, Mathiessen A, Müller KE, Aaløkken TM, Skjønsberg OH, Lerum TV, Aukrust P, Dahl TB (2022)
Markers of cellular senescence is associated with persistent pulmonary pathology after COVID-19 infection
Infect Dis (Lond), 54 (12), 918-923
DOI 10.1080/23744235.2022.2113135, PubMed 35984738

Murphy SL, Halvorsen B, Barratt-Due A, Dyrhol-Riise AM, Aukrust P, Trøseid M, Dahl TB (2022)
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611

Olsen MB, Huse C, de Sousa MML, Murphy SL, Sarno A, Obermann TS, Yang K, Holter JC, Jørgensen MJ, Christensen EE, Wang W, Ji P, Heggelund L, Hoel H, Dyrhol-Riise AM, Gregersen I, Aukrust P, Bjørås M, Halvorsen B, Dahl TB (2022)
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients
J Inflamm Res, 15, 6629-6644
DOI 10.2147/JIR.S379331, PubMed 36514358

Quiles-Jiménez A, Dahl TB, Bjørås M, Alseth I, Halvorsen B, Gregersen I (2022)
Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies
Stroke, 53 (6), 2114-2122
DOI 10.1161/STROKEAHA.121.037581, PubMed 35240858

Ratajczak-Tretel B, Tancin Lambert A, Al-Ani R, Arntzen K, Bakkejord GK, Bekkeseth H, Bjerkeli V, Eldøen G, Gulsvik A, Halvorsen B, Høie GA, Ihle-Hansen H, Ihle-Hansen H, Ingebrigtsen S, Johansen H, Kremer C, Krogseth SB, Kruuse C, Kurz M, Nakstad I, Novotny V, Næss H, Qazi R, Rezaj MK, Rørholt DM et al. (2022)
Atrial fibrillation in cryptogenic stroke and TIA patients in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Main results
Eur Stroke J, 8 (1), 148-156
DOI 10.1177/23969873221123122, PubMed 37021182

Ratajczak-Tretel B, Tancin Lambert A, Al-Ani R, Arntzen K, Bakkejord GK, Bekkeseth HMO, Bjerkeli V, Eldøen G, Gulsvik A, Halvorsen B, Høie GA, Ihle-Hansen H, Ihle-Hansen H, Ingebrigtsen S, Johansen H, Kremer C, Krogseth SB, Kruuse C, Kurz M, Nakstad I, Novotny V, Næss 18 H, Qazi R, Rezaj MK, Rørholt DM et al. (2022)
Atrial fibrillation in cryptogenic stroke and TIA patients in The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Main results
European Stroke Journal, 0 (0), 1-9
DOI 10.1177/23969873221123122, PublikaID 431

Simeone P, Tripaldi R, Michelsen A, Ueland T, Liani R, Ciotti S, Birkeland KI, Gulseth HL, Di Castelnuovo A, Cipollone F, Aukrust P, Consoli A, Halvorsen B, Santilli F (2022)
Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss
Cardiovasc Diabetol, 21 (1), 36
DOI 10.1186/s12933-022-01469-w, PubMed 35277168

Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep, 12 (1), 22378
DOI 10.1038/s41598-022-26759-x, PubMed 36572703

Søraas A, Grødeland G, Granerud BK, Ueland T, Lind A, Fevang B, Murphy SL, Huse C, Nygaard AB, Steffensen AK, Al-Baldawi H, Holberg-Petersen M, Andresen LL, Ågnes C, Ranheim T, Schanke Y, Istre M, Dahl JA, Chopra A, Dudman S, Kaarbø M, Andersen JT, Vaage EB, Tran TT, Vaage JT et al. (2022)
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859

Trøseid M, Dahl TB, Holter JC, Kildal AB, Murphy SL, Yang K, Quiles-Jiménez A, Heggelund L, Müller KE, Tveita A, Michelsen AE, Bøe S, Holten AR, Hoel H, Mathiessen A, Aaløkken TM, Fevang B, Granerud BK, Tonby K, Henriksen KN, Lerum TV, Müller F, Skjønsberg OH, Barratt-Due A, Dyrhol-Riise AM et al. (2022)
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589

Tveita A, Murphy SL, Holter JC, Kildal AB, Michelsen AE, Lerum TV, Kaarbø M, Heggelund L, Holten AR, Finbråten AK, Müller KE, Mathiessen A, Bøe S, Fevang B, Granerud BK, Tonby K, Lind A, Dudman SG, Henriksen KN, Müller F, Skjønsberg OH, Trøseid M, Barratt-Due A, Dyrhol-Riise AM, Aukrust P et al. (2022)
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699

Ueland T, Hausberg I, Mørtberg TV, Dahl TB, Lerum TV, Michelsen A, Ranheim T, Nezvalova Henriksen K, Dyrhol-Riise AM, Holme PA, Aaløkken TM, Skjønsberg OH, Barratt-Due A, Ahlén MT, Aukrust P, Halvorsen B (2022)
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947

Christensen EE, Jørgensen MJ, Nore KG, Dahl TB, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter JC, Holten AR, Halvorsen B, Dyrhol-Riise AM (2021)
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738

Christensen JJ, Narverud I, Ruuth M, Heier M, Jauhiainen M, Ulven SM, Bogsrud MP, Kovanen PT, Halvorsen B, Oda MN, Wium C, Retterstøl K, Öörni K, Holven KB (2021)
Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross-sectional study
J Intern Med, 290 (5), 1083-1097
DOI 10.1111/joim.13383, PubMed 34506681

Halvorsen B, Larsen BM (2021)
Identifying drivers for the direct rebound when energy efficiency is unknown. The importance of substitution and scale effects
Energy, 222, 119879
DOI 10.1016/j.energy.2021.119879

Holm S, Kared H, Michelsen AE, Kong XY, Dahl TB, Schultz NH, Nyman TA, Fladeby C, Seljeflot I, Ueland T, Stensland M, Mjaaland S, Goll GL, Nissen-Meyer LS, Aukrust P, Skagen K, Gregersen I, Skjelland M, Holme PA, Munthe LA, Halvorsen B (2021)
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870

Holt MF, Michelsen AE, Shahini N, Bjørkelund E, Bendz CH, Massey RJ, Schjalm C, Halvorsen B, Broch K, Ueland T, Gullestad L, Nilsson PH, Aukrust P, Mollnes TE, Louwe MC (2021)
The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure
Front Immunol, 12, 800978
DOI 10.3389/fimmu.2021.800978, PubMed 35003128

Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, Halvorsen B, Gregersen I (2021)
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0, PubMed 34611194

Kong XY, Huse C, Yang K, Øgaard J, Berges N, Vik ES, Nawaz MS, Quiles-Jiménez A, Abbas A, Gregersen I, Holm S, Bjerkli V, Rashidi A, Fladeby C, Suganthan R, Sagen EL, Skjelland M, Lång A, Bøe SO, Bjørås M, Aukrust P, Alseth I, Halvorsen B, Dahl TB (2021)
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J Am Heart Assoc, 10 (14), e020656
DOI 10.1161/JAHA.120.020656, PubMed 34259011

Kåsine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg Å, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR et al. (2021)
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368

Lauritzen KH, Olsen MB, Ahmed MS, Yang K, Rinholm JE, Bergersen LH, Esbensen QY, Sverkeli LJ, Ziegler M, Attramadal H, Halvorsen B, Aukrust P, Yndestad A (2021)
Instability in NAD⁺ metabolism leads to impaired cardiac mitochondrial function and communication
Elife, 10
DOI 10.7554/eLife.59828, PubMed 34343089

Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM et al. (2021)
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
Sci Immunol, 6 (66), eabf2489
DOI 10.1126/sciimmunol.abf2489, PubMed 34932384

Otterdal K, Berg A, Michelsen AE, Yndestad A, Patel S, Gregersen I, Halvorsen B, Ueland T, Langeland N, Aukrust P (2021)
IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria
BMC Infect Dis, 21 (1), 1073
DOI 10.1186/s12879-021-06751-y, PubMed 34663245

Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552

Skarpengland T, Macpherson ME, Hov JR, Kong XY, Bohov P, Halvorsen B, Fevang B, Berge RK, Aukrust P, Jørgensen SF (2021)
Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
J Clin Immunol, 42 (1), 146-157
DOI 10.1007/s10875-021-01146-9, PubMed 34669143

Publications 2020

Arain F, Abraityte A, Bogdanova M, Solberg OG, Michelsen AE, Lekva T, Aakhus S, Holm S, Halvorsen B, Finsen AV, Vinge LE, Nymo S, Espeland T, Ranheim T, Aukrust P, Vaage IJ, Auensen A, Gullestad L, Ueland T (2020)
YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis
Circ Heart Fail, 13 (10), e006643
DOI 10.1161/CIRCHEARTFAILURE.119.006643, PubMed 32962417

Gregersen I, Michelsen AE, Lunde NN, Åkerblom A, Lakic TG, Skjelland M, Ryeng Skagen K, Becker RC, Lindbäck J, Himmelmann A, Solberg R, Johansen HT, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Ueland T, Wallentin L, Halvorsen B (2020)
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial
J Am Heart Assoc, 9 (17), e016360
DOI 10.1161/JAHA.120.016360, PubMed 32809893

Hoel H, Ueland T, Knudsen A, Kjær A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Trøseid M (2020)
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280

Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538

Hovland A, Narverud I, Lie Øyri LK, Bogsrud MP, Aagnes I, Ueland T, Mulder M, Leijten F, Langslet G, Wium C, Svilaas A, Arnesen KE, Roeters van Lennep J, Aukrust P, Halvorsen B, Retterstøl K, Holven KB (2020)
Subjects with familial hypercholesterolemia have lower aortic valve area and higher levels of inflammatory biomarkers
J Clin Lipidol, 15 (1), 134-141
DOI 10.1016/j.jacl.2020.12.006, PubMed 33358307

Hovland A, Retterstøl K, Mollnes TE, Halvorsen B, Aukrust P, Lappegård KT (2020)
Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
Scand Cardiovasc J, 54 (5), 274-279
DOI 10.1080/14017431.2020.1775878, PubMed 32500743

Iordanova Schistad E, Kong XY, Furberg AS, Bäckryd E, Grimnes G, Emaus N, Rosseland LA, Gordh T, Stubhaug A, Engdahl B, Halvorsen B, Nielsen CS (2020)
A population-based study of inflammatory mechanisms and pain sensitivity
Pain, 161 (2), 338-350
DOI 10.1097/j.pain.0000000000001731, PubMed 31651577

Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667

Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155

Niyonzima N, Bakke SS, Gregersen I, Holm S, Sandanger Ø, Orrem HL, Sporsheim B, Ryan L, Kong XY, Dahl TB, Skjelland M, Sørensen KK, Rokstad AM, Yndestad A, Latz E, Gullestad L, Andersen GØ, Damås JK, Aukrust P, Mollnes TE, Halvorsen B, Espevik T (2020)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275

Otterdal K, Berg A, Michelsen AE, Patel S, Gregersen I, Sagen EL, Halvorsen B, Yndestad A, Ueland T, Langeland N, Aukrust P (2020)
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect Dis, 20 (1), 65
DOI 10.1186/s12879-020-4783-8, PubMed 31964363

Quiles-Jiménez A, Gregersen I, Mittelstedt Leal de Sousa M, Abbas A, Kong XY, Alseth I, Holm S, Dahl TB, Skagen K, Skjelland M, Aukrust P, Bjørås M, Halvorsen B (2020)
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis
Biochem Biophys Res Commun, 533 (4), 631-637
DOI 10.1016/j.bbrc.2020.09.057, PubMed 33004177

Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482

Tancin Lambert A, Kong XY, Ratajczak-Tretel B, Atar D, Russell D, Skjelland M, Bjerkeli V, Skagen K, Coq M, Schordan E, Firat H, Halvorsen B, Aamodt AH (2020)
Biomarkers Associated with Atrial Fibrillation in Patients with Ischemic Stroke: A Pilot Study from the NOR-FIB Study
Cerebrovasc Dis Extra, 10 (1), 11-20
DOI 10.1159/000504529, PubMed 32028277

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

Publications 2019

Christensen JJ, Bakke SS, Ulven SM, Retterstøl K, Henriksen T, Bollerslev J, Espevik T, Aukrust P, Halvorsen B, Holven KB (2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children
Mol Nutr Food Res, 63 (7), e1800990
DOI 10.1002/mnfr.201800990, PubMed 30702198

Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE, Øie E, Gullestad L, Halvorsen B, Hansen TV, Aukrust P, Dalli J, Yndestad A (2019)
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024, PubMed 31345784

Gravastrand CS, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen EA, Woodruff TM, Lambris JD, Mollnes TE, Brekke OL, Espevik T, Rokstad AMA (2019)
Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
J Immunol, 203 (4), 853-863
DOI 10.4049/jimmunol.1900503, PubMed 31270150

Gregersen I, Høibraaten E, Holven KB, Løvdahl L, Ueland T, Mowinckel MC, Dahl TB, Aukrust P, Halvorsen B, Sandset PM (2019)
Effect of hormone replacement therapy on atherogenic lipid profile in postmenopausal women
Thromb Res, 184, 1-7
DOI 10.1016/j.thromres.2019.10.005, PubMed 31677448

Holm S, Oma I, Hagve TA, Saatvedt K, Brosstad F, Mikkelsen K, Rydningen H, Risnes I, Almdahl SM, Ueland T, Aukrust P, Halvorsen B, Hollan I (2019)
Levels of Lipoprotein (a) in patients with coronary artery disease with and without inflammatory rheumatic disease: a cross-sectional study
BMJ Open, 9 (5), e030651
DOI 10.1136/bmjopen-2019-030651, PubMed 31079089

Isaksen K, Halvorsen B, Munk PS, Aukrust P, Larsen AI (2019)
Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure
Scand Cardiovasc J, 53 (4), 213-219
DOI 10.1080/14017431.2019.1629004, PubMed 31169417

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Larsen AI, Valborgland T, Ogne C, Lindal S, Halvorsen B, Munk PS, Kvaløy JT, Aukrust P, Yndestad A (2019)
Plasma tumour necrosis factor correlates with mRNA expression of tumour necrosis factor and mitochondrial transcription factors in skeletal muscle in patients with chronic heart failure treated with cardiac resynchronization therapy: potential role in myopathy
Eur J Prev Cardiol, 27 (19), 2362-2366
DOI 10.1177/2047487319855796, PubMed 31389718

Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Gonçalves I, Nilsson J, Grenegård M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2019)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625

Macpherson ME, Halvorsen B, Yndestad A, Ueland T, Mollnes TE, Berge RK, Rashidi A, Otterdal K, Gregersen I, Kong XY, Holven KB, Aukrust P, Fevang B, Jørgensen SF (2019)
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122

Narverud I, Bogsrud MP, Øyri LKL, Ulven SM, Retterstøl K, Ueland T, Mulder M, Roeters van Lennep J, Halvorsen B, Aukrust P, Veierød MB, Holven KB (2019)
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370

Narverud I, Christensen JJ, Bakke SS, Ulven SM, Rundblad A, Aukrust P, Espevik T, Bogsrud MP, Retterstøl K, Ueland T, Halvorsen B, Holven KB (2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426

Nome ME, Euceda LR, Jabeen S, Debik J, Bathen TF, Giskeødegård GF, Taskén KA, Maelandsmo GM, Halvorsen B, Yndestad A, Borgen E, Garred Ø, Aukrust P, Ueland T, Engebraaten O, Kristensen VN, Tekpli X (2019)
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972

Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T (2019)
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol, 197 (1), 74-82
DOI 10.1111/cei.13283, PubMed 30821848

Ratajczak-Tretel B, Lambert AT, Johansen H, Halvorsen B, Bjerkeli V, Russell D, Sandset EC, Ihle-Hansen H, Eriksen E, Næss H, Novotny V, Khanevski AN, Truelsen TC, Idicula T, Ægidius KL, Tobro H, Krogseth SB, Ihle-Hansen H, Hagberg G, Kruuse C, Arntzen K, Bakkejord GK, Villseth M, Nakstad I, Eldøen G et al. (2019)
Atrial fibrillation in cryptogenic stroke and transient ischaemic attack - The Nordic Atrial Fibrillation and Stroke (NOR-FIB) Study: Rationale and design
Eur Stroke J, 4 (2), 172-180
DOI 10.1177/2396987319837089, PubMed 31259265

Skjelland M, Zamani M, Hetlevik S, Lilleby V, Halvorsen B, Skagen K (2019)
Increased Endothelial Activation in Patients with Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis, 29 (2), 104563
DOI 10.1016/j.jstrokecerebrovasdis.2019.104563, PubMed 31831329

Sokolova M, Ranheim T, Louwe MC, Halvorsen B, Yndestad A, Aukrust P (2019)
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, Aukrust P, Christensen G, Skjønsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936

van der Vorst EPC, Daissormont I, Aslani M, Seijkens T, Wijnands E, Lutgens E, Duchene J, Santovito D, Döring Y, Halvorsen B, Aukrust P, Weber C, Höpken UE, Biessen EAL (2019)
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development
Thromb Haemost, 120 (2), 344-347
DOI 10.1055/s-0039-3400746, PubMed 31837653

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD⁺ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

Publications 2018

Abadpour S, Halvorsen B, Sahraoui A, Korsgren O, Aukrust P, Scholz H (2018)
Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT
J Mol Endocrinol, 60 (3), 171-183
DOI 10.1530/JME-17-0182, PubMed 29330151

Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
J Acquir Immune Defic Syndr, 78 (4), 450-457
DOI 10.1097/QAI.0000000000001693, PubMed 29874201

Berg J, Halvorsen AR, Bengtson MB, Taskén KA, Mælandsmo GM, Yndestad A, Halvorsen B, Brustugun OT, Aukrust P, Ueland T, Helland Å (2018)
Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
BMC Cancer, 18 (1), 739
DOI 10.1186/s12885-018-4659-0, PubMed 30005623

Kleveland O, Ueland T, Kunszt G, Bratlie M, Yndestad A, Broch K, Holte E, Ryan L, Amundsen BH, Bendz B, Aakhus S, Espevik T, Halvorsen B, Mollnes TE, Wiseth R, Gullestad L, Aukrust P, Damås JK (2018)
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Int J Cardiol, 271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572

Ormstad H, Bryn V, Verkerk R, Skjeldal OH, Halvorsen B, Saugstad OD, Isaksen J, Maes M (2018)
Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders
CNS Neurol Disord Drug Targets, 17 (8), 626-639
DOI 10.2174/1871527317666180720163221, PubMed 30033880

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sørensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB (2018)
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J Am Heart Assoc, 7 (2)
DOI 10.1161/JAHA.117.006479, PubMed 29330254

Solheim N, Gregersen I, Halvorsen B, Bjerkeli V, Stubhaug A, Gordh T, Rosseland LA (2018)
Randomized controlled trial of intra-articular ketorolac on pain and inflammation after minor arthroscopic knee surgery
Acta Anaesthesiol Scand, 62 (6), 829-838
DOI 10.1111/aas.13104, PubMed 29512121

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Aukrust P, Gullestad L, Halvorsen B, Yndestad A (2018)
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Open Heart, 5 (2), e000765
DOI 10.1136/openhrt-2017-000765, PubMed 30258647

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Holven KB, Aukrust P, Gullestad L, Yndestad A, Halvorsen B (2018)
Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Int J Cardiol, 274, 348-350
DOI 10.1016/j.ijcard.2018.06.093, PubMed 29961573

Publications 2017

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T (2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312

Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL (2017)
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
Arterioscler Thromb Vasc Biol, 37 (6), 1157-1167
DOI 10.1161/ATVBAHA.116.308187, PubMed 28408371

Christensen JJ, Ulven SM, Retterstøl K, Narverud I, Bogsrud MP, Henriksen T, Bollerslev J, Halvorsen B, Aukrust P, Holven KB (2017)
Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study
Atherosclerosis, 266, 48-57
DOI 10.1016/j.atherosclerosis.2017.09.021, PubMed 28963918

Espada S, Stavik B, Holm S, Sagen EL, Bjerkeli V, Skjelland M, Dahl TB, Espevik T, Kanse S, Sandset PM, Skretting G, Halvorsen B (2017)
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem Biophys Res Commun, 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070, PubMed 28712870

Gregersen I, Sandanger Ø, Askevold ET, Sagen EL, Yang K, Holm S, Pedersen TM, Skjelland M, Krohg-Sørensen K, Hansen TV, Dahl TB, Otterdal K, Espevik T, Aukrust P, Yndestad A, Halvorsen B (2017)
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
PLoS One, 12 (11), e0188387
DOI 10.1371/journal.pone.0188387, PubMed 29176764

Retterstøl K, Narverud I, Selmer R, Berge KE, Osnes IV, Ulven SM, Halvorsen B, Aukrust P, Holven KB, Iversen PO (2017)
Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics
Lipids Health Dis, 16 (1), 115
DOI 10.1186/s12944-017-0511-9, PubMed 28606150

Stavik B, Holm S, Espada S, Iversen N, Sporsheim B, Bjerkeli V, Dahl TB, Sandset PM, Skjelland M, Espevik T, Skretting G, Halvorsen B (2017)
Increased expression of TFPI in human carotid stenosis
Thromb Res, 155, 31-37
DOI 10.1016/j.thromres.2017.04.024, PubMed 28482260

Publications 2016

Christensen JJ, Osnes L, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551

Christensen JJ, Osnes LT, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183

Halvorsen B, Larsen BM, Wilhite H, Winther T (2016)
Revisiting household energy rebound: Perspectives from a multidisciplinary study
Indoor Built Environ., 25 (7), 1114-1123
DOI 10.1177/1420326X16629725

Halvorsen B, Santilli F, Scholz H, Sahraoui A, Gulseth HL, Wium C, Lattanzio S, Formoso G, Di Fulvio P, Otterdal K, Retterstøl K, Holven KB, Gregersen I, Stavik B, Bjerkeli V, Michelsen AE, Ueland T, Liani R, Davi G, Aukrust P (2016)
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
Diabetologia, 59 (10), 2134-44
DOI 10.1007/s00125-016-4036-y, PubMed 27421726

Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597

Lunde NN, Holm S, Dahl TB, Elyouncha I, Sporsheim B, Gregersen I, Abbas A, Skjelland M, Espevik T, Solberg R, Johansen HT, Halvorsen B (2016)
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis
Atherosclerosis, 257, 216-223
DOI 10.1016/j.atherosclerosis.2016.11.026, PubMed 27940038

Narverud I, Myhrstad MC, Herzig KH, Karhu T, Dahl TB, Halvorsen B, Ulven SM, Holven KB (2016)
Lack of Effects of a Single High-Fat Meal Enriched with Vegetable n-3 or a Combination of Vegetable and Marine n-3 Fatty Acids on Intestinal Peptide Release and Adipokines in Healthy Female Subjects
Front Nutr, 3, 38
DOI 10.3389/fnut.2016.00038, PubMed 27630989

Niyonzima N, Halvorsen B, Sporsheim B, Garred P, Aukrust P, Mollnes TE, Espevik T (2016)
Complement activation by cholesterol crystals triggers a subsequent cytokine response
Mol Immunol, 84, 43-50
DOI 10.1016/j.molimm.2016.09.019, PubMed 27692470

Otterdal K, Portillo A, Astrup E, Ludviksen J, Davì G, Holm S, Santilli F, Vitale G, Raoult D, Olano JP, Schjalm C, Halvorsen B, Oteo JA, Mollnes TE, Aukrust P, Nilsson PH (2016)
High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
Cytokine, 83, 269-274
DOI 10.1016/j.cyto.2016.05.006, PubMed 27180202

Otterdal K, Portillo A, Astrup E, Ludviksen JK, Schjalm C, Raoult D, Olano JP, Halvorsen B, Oteo JA, Aukrust P, Mollnes TE, Nilsson PH (2016)
Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
Clin Microbiol Infect, 22 (8), 734.e1-6
DOI 10.1016/j.cmi.2016.05.010, PubMed 27217049

Ottestad I, Nordvi B, Vogt G, Holck M, Halvorsen B, Brønner KW, Retterstøl K, Holven KB, Nilsson A, Ulven SM (2016)
Bioavailability of n-3 fatty acids from n-3-enriched foods and fish oil with different oxidative quality in healthy human subjects: a randomised single-meal cross-over study
J Nutr Sci, 5, e43
DOI 10.1017/jns.2016.34, PubMed 28620470

Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A (2016)
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis
J Am Heart Assoc, 5 (5)
DOI 10.1161/JAHA.115.003031, PubMed 27207962

Pilely K, Rosbjerg A, Genster N, Gal P, Pál G, Halvorsen B, Holm S, Aukrust P, Bakke SS, Sporsheim B, Nervik I, Niyonzima N, Bartels ED, Stahl GL, Mollnes TE, Espevik T, Garred P (2016)
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
J Immunol, 196 (12), 5064-74
DOI 10.4049/jimmunol.1502595, PubMed 27183610

Sikkeland LI, Johnsen HL, Riste TB, Alexis NE, Halvorsen B, Søyseth V, Kongerud J (2016)
Sputum neutrophils are elevated in smelter workers, and systemic neutrophils are associated with rapid decline in FEV1
Occup Environ Med, 73 (7), 459-66
DOI 10.1136/oemed-2015-103083, PubMed 27052769

Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510

Skarpengland T, Dahl TB, Skjelland M, Scheffler K, de Sousa MML, Gregersen I, Kuśnierczyk A, Sharma A, Slupphaug G, Eide L, Segers FM, Skagen KR, Dahl CP, Russell D, Folkersen L, Krohg-Sørensen K, Holm S, Bjørås M, Aukrust P, Halvorsen B (2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A et al. (2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939

Stavik B, Espada S, Cui XY, Iversen N, Holm S, Mowinkel MC, Halvorsen B, Skretting G, Sandset PM (2016)
EPAS1/HIF-2 alpha-mediated downregulation of tissue factor pathway inhibitor leads to a pro-thrombotic potential in endothelial cells
Biochim Biophys Acta, 1862 (4), 670-678
DOI 10.1016/j.bbadis.2016.01.017, PubMed 26826018

Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E (2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming
Sci Transl Med, 8 (333), 333ra50
DOI 10.1126/scitranslmed.aad6100, PubMed 27053774

Publications 2015

Abbas A, Gregersen I, Holm S, Daissormont I, Bjerkeli V, Krohg-Sørensen K, Skagen KR, Dahl TB, Russell D, Almås T, Bundgaard D, Alteheld LH, Rashidi A, Dahl CP, Michelsen AE, Biessen EA, Aukrust P, Halvorsen B, Skjelland M (2015)
Interleukin 23 levels are increased in carotid atherosclerosis: possible role for the interleukin 23/interleukin 17 axis
Stroke, 46 (3), 793-9
DOI 10.1161/STROKEAHA.114.006516, PubMed 25649806

Bryn V, Halvorsen B, Ueland T, Isaksen J, Kolkova K, Ravn K, Skjeldal OH (2015)
Brain derived neurotrophic factor (BDNF) and autism spectrum disorders (ASD) in childhood
Eur J Paediatr Neurol, 19 (4), 411-4
DOI 10.1016/j.ejpn.2015.03.005, PubMed 25847750

Gregersen I, Holm S, Dahl TB, Halvorsen B, Aukrust P (2015)
A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases
Expert Rev Cardiovasc Ther, 14 (3), 391-403
DOI 10.1586/14779072.2016.1128828, PubMed 26641944

Halvorsen B, Espeland MZ, Andersen GØ, Yndestad A, Sagen EL, Rashidi A, Knudsen EC, Skjelland M, Skagen KR, Krohg-Sørensen K, Holm S, Ritschel V, Holven KB, Biessen EA, Aukrust P, Dahl TB (2015)
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139

Narverud I, van Lennep JR, Christensen JJ, Versmissen J, Gran JM, Iversen PO, Aukrust P, Halvorsen B, Ueland T, Ulven SM, Ose L, Veierød MB, Sijbrands E, Retterstøl K, Holven KB (2015)
Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia
Atherosclerosis, 243 (1), 155-60
DOI 10.1016/j.atherosclerosis.2015.09.014, PubMed 26386212

Otterdal K, Haukeland JW, Yndestad A, Dahl TB, Holm S, Segers FM, Gladhaug IP, Konopski Z, Damås JK, Halvorsen B, Aukrust P (2015)
Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation
Clin Transl Gastroenterol, 6 (7), e95
DOI 10.1038/ctg.2015.23, PubMed 26133108

Skarpengland T, Laugsand LE, Janszky I, Luna L, Halvorsen B, Platou CG, Wang W, Vatten LJ, Damås JK, Aukrust P, Bjørås M, Åsvold BO (2015)
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study
DNA Repair (Amst), 28, 21-7
DOI 10.1016/j.dnarep.2015.01.013, PubMed 25703835

Publications 2014

Abbas A, Aukrust P, Russell D, Krohg-Sørensen K, Almås T, Bundgaard D, Bjerkeli V, Sagen EL, Michelsen AE, Dahl TB, Holm S, Ueland T, Skjelland M, Halvorsen B (2014)
Matrix metalloproteinase 7 is associated with symptomatic lesions and adverse events in patients with carotid atherosclerosis
PLoS One, 9 (1), e84935
DOI 10.1371/journal.pone.0084935, PubMed 24400123

Bot I, Daissormont IT, Zernecke A, van Puijvelde GH, Kramp B, de Jager SC, Sluimer JC, Manca M, Hérias V, Westra MM, Bot M, van Santbrink PJ, van Berkel TJ, Su L, Skjelland M, Gullestad L, Kuiper J, Halvorsen B, Aukrust P, Koenen RR, Weber C, Biessen EA (2014)
CXCR4 blockade induces atherosclerosis by affecting neutrophil function
J Mol Cell Cardiol, 74, 44-52
DOI 10.1016/j.yjmcc.2014.04.021, PubMed 24816217

Halvorsen B, Dahl TB, Smedbakken LM, Singh A, Michelsen AE, Skjelland M, Krohg-Sørensen K, Russell D, Höpken UE, Lipp M, Damås JK, Holm S, Yndestad A, Biessen EA, Aukrust P (2014)
Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells
Cardiovasc Res, 102 (1), 148-56
DOI 10.1093/cvr/cvu036, PubMed 24518141

Halvorsen B, Holm S, Yndestad A, Scholz H, Sagen EL, Nebb H, Holven KB, Dahl TB, Aukrust P (2014)
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α
Biochem Biophys Res Commun, 450 (4), 1525-30
DOI 10.1016/j.bbrc.2014.07.036, PubMed 25035925

Halvorsen B, Smedbakken LM, Michelsen AE, Skjelland M, Bjerkeli V, Sagen EL, Taskén K, Bendz B, Gullestad L, Holm S, Biessen EA, Aukrust P (2014)
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
Atherosclerosis, 234 (2), 352-9
DOI 10.1016/j.atherosclerosis.2014.03.021, PubMed 24732574

Holven KB, Narverud I, Lindvig HW, Halvorsen B, Langslet G, Nenseter MS, Ulven SM, Ose L, Aukrust P, Retterstøl K (2014)
Subjects with familial hypercholesterolemia are characterized by an inflammatory phenotype despite long-term intensive cholesterol lowering treatment
Atherosclerosis, 233 (2), 561-567
DOI 10.1016/j.atherosclerosis.2014.01.022, PubMed 24530965

Narverud I, Retterstøl K, Iversen PO, Halvorsen B, Ueland T, Ulven SM, Ose L, Aukrust P, Veierød MB, Holven KB (2014)
Markers of atherosclerotic development in children with familial hypercholesterolemia: a literature review
Atherosclerosis, 235 (2), 299-309
DOI 10.1016/j.atherosclerosis.2014.05.917, PubMed 24908240

Parolini C, Vik R, Busnelli M, Bjørndal B, Holm S, Brattelid T, Manzini S, Ganzetti GS, Dellera F, Halvorsen B, Aukrust P, Sirtori CR, Nordrehaug JE, Skorve J, Berge RK, Chiesa G (2014)
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in ApoE-deficient mice
PLoS One, 9 (5), e97598
DOI 10.1371/journal.pone.0097598, PubMed 24840793

Trøseid M, Ueland T, Hov JR, Svardal A, Gregersen I, Dahl CP, Aakhus S, Gude E, Bjørndal B, Halvorsen B, Karlsen TH, Aukrust P, Gullestad L, Berge RK, Yndestad A (2014)
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
J Intern Med, 277 (6), 717-26
DOI 10.1111/joim.12328, PubMed 25382824

Publications 2013

Gregersen I, Skjelland M, Holm S, Holven KB, Krogh-Sørensen K, Russell D, Askevold ET, Dahl CP, Ørn S, Gullestad L, Mollnes TE, Ueland T, Aukrust P, Halvorsen B (2013)
Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
PLoS One, 8 (8), e72769
DOI 10.1371/journal.pone.0072769, PubMed 24023645

Hamre H, Zeller B, Kanellopoulos A, Ruud E, Fosså SD, Loge JH, Aukrust P, Halvorsen B, Mollnes TE, Kiserud CE (2013)
Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma
Brain Behav Immun, 30, 80-7
DOI 10.1016/j.bbi.2013.01.006, PubMed 23333795

Holven KB, Retterstøl K, Ueland T, Ulven SM, Nenseter MS, Sandvik M, Narverud I, Berge KE, Ose L, Aukrust P, Halvorsen B (2013)
Subjects with low plasma HDL cholesterol levels are characterized by an inflammatory and oxidative phenotype
PLoS One, 8 (11), e78241
DOI 10.1371/journal.pone.0078241, PubMed 24244297

Lillemo SC, Alfnes F, Halvorsen B, Wik M (2013)
Households' heating investments: The effect of motives and attitudes on choice of equipment
Biomass Bioenerg., 57, 4-12
DOI 10.1016/j.biombioe.2013.01.027

Lillemo SC, Halvorsen B (2013)
The impact of lifestyle and attitudes on residential firewood demand in Norway
Biomass Bioenerg., 57, 13-21
DOI 10.1016/j.biombioe.2013.01.024

Telle-Hansen VH, Halvorsen B, Dalen KT, Narverud I, Wesseltoft-Rao N, Granlund L, Ulven SM, Holven KB (2013)
Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype
Genes Nutr, 8 (4), 425-34
DOI 10.1007/s12263-012-0329-z, PubMed 23296345

Vik R, Busnelli M, Parolini C, Bjørndal B, Holm S, Bohov P, Halvorsen B, Brattelid T, Manzini S, Ganzetti GS, Dellera F, Nygård OK, Aukrust P, Sirtori CR, Chiesa G, Berge RK (2013)
An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoe(-/-) mice
PLoS One, 8 (12), e81963
DOI 10.1371/journal.pone.0081963, PubMed 24324736

Wangensteen T, Retterstøl L, Rødningen OK, Hjelmesaeth J, Aukrust P, Halvorsen B (2013)
De novo 19p13.2 microdeletion encompassing the insulin receptor and resistin genes in a patient with obesity and learning disability
Am J Med Genet A, 161A (6), 1480-6
DOI 10.1002/ajmg.a.35927, PubMed 23637016

Publications 2012

Abbas A, Aukrust P, Dahl TB, Bjerkeli V, Sagen EB, Michelsen A, Russell D, Krohg-Sørensen K, Holm S, Skjelland M, Halvorsen B (2012)
High levels of S100A12 are associated with recent plaque symptomatology in patients with carotid atherosclerosis
Stroke, 43 (5), 1347-53
DOI 10.1161/STROKEAHA.111.642256, PubMed 22382154

Astrup E, Lekva T, Davì G, Otterdal K, Santilli F, Oie E, Halvorsen B, Damås JK, Raoult D, Vitale G, Olano JP, Ueland T, Aukrust P (2012)
A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells
PLoS One, 7 (9), e43638
DOI 10.1371/journal.pone.0043638, PubMed 23028464

Dahl TB, Bermudez B, Ranheim T, Otterdal K, Holm S, Biessen EAL, Halvorsen B, Aukrust P (2012)
Unraveling the role of nicotinamide phosphoribosyltransferase on lipids in atherosclerosis
Clin. Lipidol., 7 (6), 697-707
DOI 10.2217/CLP.12.71

Dahl TB, Holm S, Aukrust P, Halvorsen B (2012)
Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology
Annu Rev Nutr, 32, 229-43
DOI 10.1146/annurev-nutr-071811-150746, PubMed 22462624

Halvorsen B, Dahl TB, Aukrust P (2012)
Visfatin/NAMPT - a hot spot in thrombosis?
Thromb Res, 130 (3), 289-90
DOI 10.1016/j.thromres.2012.06.027, PubMed 22809845

Hol J, Otterdal K, Breland UM, Stang E, Pedersen TM, Hagelsteen K, Ranheim T, Kasprzycka M, Halvorsen B, Haraldsen G, Aukrust P (2012)
Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies
PLoS One, 7 (7), e40673
DOI 10.1371/journal.pone.0040673, PubMed 22815786

Liani R, Halvorsen B, Sestili S, Handberg A, Santilli F, Vazzana N, Formoso G, Aukrust P, Davì G (2012)
Plasma levels of soluble CD36, platelet activation, inflammation, and oxidative stress are increased in type 2 diabetic patients
Free Radic Biol Med, 52 (8), 1318-24
DOI 10.1016/j.freeradbiomed.2012.02.012, PubMed 22343420

Narverud I, Halvorsen B, Nenseter MS, Retterstøl K, Yndestad A, Dahl TB, Ulven SM, Olstad OK, Ose L, Holven KB, Aukrust P (2012)
Oxidized LDL level is related to gene expression of tumour necrosis factor super family members in children and young adults with familial hypercholesterolaemia
J Intern Med, 273 (1), 69-78
DOI 10.1111/j.1365-2796.2012.02584.x, PubMed 22891927

Narverud I, Iversen PO, Aukrust P, Halvorsen B, Ueland T, Johansen SG, Nenseter MS, Sandset PM, Ulven SM, Ose L, Retterstøl K, Holven KB (2012)
Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH
Thromb Res, 131 (2), 178-82
DOI 10.1016/j.thromres.2012.11.008, PubMed 23199546

Nenseter MS, Bogsrud MP, Græsdal A, Narverud I, Halvorsen B, Ose L, Aukrust P, Holven KB (2012)
LDL-apheresis affects markers of endothelial function in patients with homozygous familial hypercholesterolemia
Thromb Res, 130 (5), 823-5
DOI 10.1016/j.thromres.2012.06.004, PubMed 22728023

Nenseter MS, Narverud I, Græsdal A, Bogsrud MP, Aukrust P, Retterstøl K, Ose L, Halvorsen B, Holven KB (2012)
Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis
J Clin Lipidol, 7 (2), 109-16
DOI 10.1016/j.jacl.2012.08.001, PubMed 23415429

Nenseter MS, Narverud I, Græsdal A, Bogsrud MP, Halvorsen B, Ose L, Aukrust P, Holven KB (2012)
Elevated serum MMP-9/TIMP-1 ratio in patients with homozygous familial hypercholesterolemia: effects of LDL-apheresis
Cytokine, 61 (1), 194-8
DOI 10.1016/j.cyto.2012.09.016, PubMed 23131422

Olarescu NC, Ueland T, Lekva T, Dahl TB, Halvorsen B, Aukrust P, Bollerslev J (2012)
Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
J Clin Endocrinol Metab, 97 (4), 1355-62
DOI 10.1210/jc.2011-2417, PubMed 22319029

Smedbakken LM, Halvorsen B, Daissormont I, Ranheim T, Michelsen AE, Skjelland M, Sagen EL, Folkersen L, Krohg-Sørensen K, Russell D, Holm S, Ueland T, Fevang B, Hedin U, Yndestad A, Gullestad L, Hansson GK, Biessen EA, Aukrust P (2012)
Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Atherosclerosis, 224 (1), 266-73
DOI 10.1016/j.atherosclerosis.2012.06.071, PubMed 22840692

Telle-Hansen VH, Narverud I, Retterstøl K, Wesseltoft-Rao N, Mosdøl A, Granlund L, Christiansen KF, Lamglait A, Halvorsen B, Holven KB, Ulven SM (2012)
Substitution of TAG oil with diacylglycerol oil in food items improves the predicted 10 years cardiovascular risk score in healthy, overweight subjects
J Nutr Sci, 1, e17
DOI 10.1017/jns.2012.18, PubMed 25191546

Publications 2011

Andersen GØ, Ueland T, Knudsen EC, Scholz H, Yndestad A, Sahraoui A, Smith C, Lekva T, Otterdal K, Halvorsen B, Seljeflot I, Aukrust P (2011)
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
DOI 10.2337/db10-1493, PubMed 21464440

Berdal JE, Mollnes TE, Wæhre T, Olstad OK, Halvorsen B, Ueland T, Laake JH, Furuseth MT, Maagaard A, Kjekshus H, Aukrust P, Jonassen CM (2011)
Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
J Infect, 63 (4), 308-16
DOI 10.1016/j.jinf.2011.07.004, PubMed 21781987

Dahl T, Ranheim T, Holm S, Berge R, Aukrust P, Halvorsen B (2011)
Nicotinamide phosphoribosyltransferase and lipid accumulation in macrophages
Eur J Clin Invest, 41 (10), 1098-104
DOI 10.1111/j.1365-2362.2011.02515.x, PubMed 21426336

Daissormont IT, Christ A, Temmerman L, Sampedro Millares S, Seijkens T, Manca M, Rousch M, Poggi M, Boon L, van der Loos C, Daemen M, Lutgens E, Halvorsen B, Aukrust P, Janssen E, Biessen EA (2011)
Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity
Circ Res, 109 (12), 1387-95
DOI 10.1161/CIRCRESAHA.111.256529, PubMed 22021930

Haukeland JW, Dahl TB, Yndestad A, Gladhaug IP, Løberg EM, Haaland T, Konopski Z, Wium C, Aasheim ET, Johansen OE, Aukrust P, Halvorsen B, Birkeland KI (2011)
Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies
Eur J Endocrinol, 166 (3), 503-10
DOI 10.1530/EJE-11-0864, PubMed 22170794

Holm S, Ueland T, Dahl TB, Michelsen AE, Skjelland M, Russell D, Nymo SH, Krohg-Sørensen K, Clausen OP, Atar D, Januzzi JL, Aukrust P, Jensen JK, Halvorsen B (2011)
Fatty Acid binding protein 4 is associated with carotid atherosclerosis and outcome in patients with acute ischemic stroke
PLoS One, 6 (12), e28785
DOI 10.1371/journal.pone.0028785, PubMed 22174896

Larsen KO, Yndestad A, Sjaastad I, Løberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjønsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626

Myhrstad MC, Narverud I, Telle-Hansen VH, Karhu T, Lund DB, Herzig KH, Makinen M, Halvorsen B, Retterstøl K, Kirkhus B, Granlund L, Holven KB, Ulven SM (2011)
Effect of the fat composition of a single high-fat meal on inflammatory markers in healthy young women
Br J Nutr, 106 (12), 1826-35
DOI 10.1017/S0007114511002510, PubMed 21736782

Myhrstad MC, Retterstøl K, Telle-Hansen VH, Ottestad I, Halvorsen B, Holven KB, Ulven SM (2011)
Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors
Inflamm Res, 60 (4), 309-19
DOI 10.1007/s00011-010-0302-5, PubMed 21229287

Smedbakken L, Jensen JK, Hallén J, Atar D, Januzzi JL, Halvorsen B, Aukrust P, Ueland T (2011)
Activated leukocyte cell adhesion molecule and prognosis in acute ischemic stroke
Stroke, 42 (9), 2453-8
DOI 10.1161/STROKEAHA.110.612440, PubMed 21757661

Søyland E, Heier I, Rodríguez-Gallego C, Mollnes TE, Johansen FE, Holven KB, Halvorsen B, Aukrust P, Jahnsen FL, de la Rosa Carrillo D, Krogstad AL, Nenseter MS (2011)
Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
Br J Dermatol, 164 (2), 344-55
DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993

Ueland T, Smedbakken LM, Hallén J, Atar D, Januzzi JL, Halvorsen B, Jensen JK, Aukrust P (2011)
Soluble CXCL16 and long-term outcome in acute ischemic stroke
Atherosclerosis, 220 (1), 244-9
DOI 10.1016/j.atherosclerosis.2011.10.004, PubMed 22055341

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157

Yndestad A, Haukeland JW, Dahl TB, Halvorsen B, Aukrust P (2011)
Activin A in nonalcoholic fatty liver disease
Vitam Horm, 85, 323-42
DOI 10.1016/B978-0-12-385961-7.00015-9, PubMed 21353887

Publications 2010

Aukrust P, Halvorsen B, Ueland T, Michelsen AE, Skjelland M, Gullestad L, Yndestad A, Otterdal K (2010)
Activated platelets and atherosclerosis
Expert Rev Cardiovasc Ther, 8 (9), 1297-307
DOI 10.1586/erc.10.92, PubMed 20828352

Aukrust P, Sandberg WJ, Otterdal K, Vinge LE, Gullestad L, Yndestad A, Halvorsen B, Ueland T (2010)
Tumor necrosis factor superfamily molecules in acute coronary syndromes
Ann Med, 43 (2), 90-103
DOI 10.3109/07853890.2010.523711, PubMed 21039303

Breland UM, Michelsen AE, Skjelland M, Folkersen L, Krohg-Sørensen K, Russell D, Ueland T, Yndestad A, Paulsson-Berne G, Damås JK, Oie E, Hansson GK, Halvorsen B, Aukrust P (2010)
Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation
Cardiovasc Res, 86 (2), 265-73
DOI 10.1093/cvr/cvq044, PubMed 20139115

Dahl TB, Haukeland JW, Yndestad A, Ranheim T, Gladhaug IP, Damås JK, Haaland T, Løberg EM, Arntsen B, Birkeland K, Bjøro K, Ulven SM, Konopski Z, Nebb HI, Aukrust P, Halvorsen B (2010)
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
J Clin Endocrinol Metab, 95 (6), 3039-47
DOI 10.1210/jc.2009-2148, PubMed 20392873

Hoekstra M, van der Lans CA, Halvorsen B, Gullestad L, Kuiper J, Aukrust P, van Berkel TJ, Biessen EA (2010)
The peripheral blood mononuclear cell microRNA signature of coronary artery disease
Biochem Biophys Res Commun, 394 (3), 792-7
DOI 10.1016/j.bbrc.2010.03.075, PubMed 20230787

Michelsen AE, Rathcke CN, Skjelland M, Holm S, Ranheim T, Krohg-Sørensen K, Klingvall MF, Brosstad F, Oie E, Vestergaard H, Aukrust P, Halvorsen B (2010)
Increased YKL-40 expression in patients with carotid atherosclerosis
Atherosclerosis, 211 (2), 589-95
DOI 10.1016/j.atherosclerosis.2010.02.035, PubMed 20347092

Narverud I, Ueland T, Nenseter MS, Retterstøl K, Telle-Hansen VH, Halvorsen B, Ose L, Aukrust P, Holven KB (2010)
Children with familial hypercholesterolemia are characterized by an inflammatory imbalance between the tumor necrosis factor α system and interleukin-10
Atherosclerosis, 214 (1), 163-8
DOI 10.1016/j.atherosclerosis.2010.10.002, PubMed 21040915

Rødland EK, Ager-Wick E, Halvorsen B, Müller F, Frøland SS (2010)
Toll like receptor 5 (TLR5) may be involved in the immunological response to Aspergillus fumigatus in vitro
Med Mycol, 49 (4), 375-9
DOI 10.3109/13693786.2010.531772, PubMed 21067314

Solaas K, Legry V, Retterstol K, Berg PR, Holven KB, Ferrières J, Amouyel P, Lien S, Romeo J, Valtueña J, Widhalm K, Ruiz JR, Dallongeville J, Tonstad S, Rootwelt H, Halvorsen B, Nenseter MS, Birkeland KI, Thorsby PM, Meirhaeghe A, Nebb HI (2010)
Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)
BMC Med Genet, 11, 144
DOI 10.1186/1471-2350-11-144, PubMed 20939869

Publications 2009

Cameron J, Ranheim T, Halvorsen B, Kulseth MA, Leren TP, Berge KE (2009)
Tangier disease caused by compound heterozygosity for ABCA1 mutations R282X and Y1532C
Atherosclerosis, 209 (1), 163-6
DOI 10.1016/j.atherosclerosis.2009.08.039, PubMed 19765707

Dahl CP, Husberg C, Gullestad L, Waehre A, Damås JK, Vinge LE, Finsen AV, Ueland T, Florholmen G, Aakhus S, Halvorsen B, Aukrust P, Oie E, Yndestad A, Christensen G (2009)
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988

Damås JK, Landrø L, Fevang B, Heggelund L, Tjønnfjord GE, Fløisand Y, Halvorsen B, Frøland SS, Aukrust P (2009)
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication
Clin Exp Immunol, 157 (3), 400-7
DOI 10.1111/j.1365-2249.2009.03976.x, PubMed 19664149

Fevang B, Yndestad A, Damås JK, Halvorsen B, Holm AM, Beiske K, Aukrust P, Frøland SS (2009)
Chemokines and common variable immunodeficiency; possible contribution of CCL19, CCL21 and CCR7 to immune dysregulation
Clin Exp Immunol, 158 (2), 237-45
DOI 10.1111/j.1365-2249.2009.04013.x, PubMed 19747210

Halvorsen B, Heggen E, Ueland T, Smith C, Sandberg WJ, Damås JK, Otterdal K, Tonstad S, Aukrust P (2009)
Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptor antagonist in individuals with metabolic syndrome
Eur J Endocrinol, 162 (2), 267-73
DOI 10.1530/EJE-09-0706, PubMed 19926782

Kolsgaard ML, Wangensteen T, Brunborg C, Joner G, Holven KB, Halvorsen B, Aukrust P, Tonstad S (2009)
Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome
Scand J Clin Lab Invest, 69 (8), 858-64
DOI 10.3109/00365510903348677, PubMed 19929281

Landrø L, Damås JK, Halvorsen B, Fevang B, Ueland T, Otterdal K, Heggelund L, Frøland SS, Aukrust P (2009)
CXCL16 in HIV infection - a link between inflammation and viral replication
Eur J Clin Invest, 39 (11), 1017-24
DOI 10.1111/j.1365-2362.2009.02207.x, PubMed 19674076

Rødland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Frøland SS (2009)
Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis
Infect Immun, 78 (3), 1269-75
DOI 10.1128/IAI.01091-09, PubMed 20008537

Sandberg WJ, Otterdal K, Gullestad L, Halvorsen B, Ragnarsson A, Frøland SS, Damås JK, Oie E, Aukrust P, Hansson GK, Yndestad A (2009)
The tumour necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis
Thromb Haemost, 102 (4), 704-10
DOI 10.1160/TH08-10-0665, PubMed 19806256

Sikkeland LI, Eduard W, Stangeland AM, Thorgersen EB, Haug T, Aukrust P, Halvorsen B, Mollnes TE, Kongerud J (2009)
Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
Inhal Toxicol, 21 (8), 674-81
DOI 10.1080/08958370802491425, PubMed 19558225

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust P, Bollerslev J (2009)
Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly
J Clin Endocrinol Metab, 95 (1), 361-8
DOI 10.1210/jc.2009-0422, PubMed 19880791

Ueland T, Fougner SL, Godang K, Lekva T, Schurgers LJ, Scholz H, Halvorsen B, Schreiner T, Aukrust PL, Bollerslev J (2009)
Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly
Endocr Rev, 30 (7), 927
DOI 10.1210/edrv.30.7.9997, PubMed 28199500

Ueland T, Otterdal K, Lekva T, Halvorsen B, Gabrielsen A, Sandberg WJ, Paulsson-Berne G, Pedersen TM, Folkersen L, Gullestad L, Oie E, Hansson GK, Aukrust P (2009)
Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis
Arterioscler Thromb Vasc Biol, 29 (8), 1228-34
DOI 10.1161/ATVBAHA.109.189761, PubMed 19498175

Yndestad A, Haukeland JW, Dahl TB, Bjøro K, Gladhaug IP, Berge C, Damås JK, Haaland T, Løberg EM, Linnestad P, Birkeland K, Konopski Z, Halvorsen B, Berge RK, Aukrust P (2009)
A complex role of activin A in non-alcoholic fatty liver disease
Am J Gastroenterol, 104 (9), 2196-205
DOI 10.1038/ajg.2009.318, PubMed 19532130

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjønsberg OH, Pedersen TM, Anfinsen OG, Damås JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
DOI 10.1152/japplphysiol.90719.2008, PubMed 19196915

Publications 2008

Aukrust P, Halvorsen B, Yndestad A, Ueland T, Øie E, Otterdal K, Gullestad L, Damås JK (2008)
Chemokines and cardiovascular risk
Arterioscler Thromb Vasc Biol, 28 (11), 1909-19
DOI 10.1161/ATVBAHA.107.161240, PubMed 18669888

Aukrust P, Otterdal K, Yndestad A, Sandberg WJ, Smith C, Ueland T, Øie E, Damås JK, Gullestad L, Halvorsen B (2008)
The complex role of T-cell-based immunity in atherosclerosis
Curr Atheroscler Rep, 10 (3), 236-43
DOI 10.1007/s11883-008-0037-8, PubMed 18489852

Breland UM, Halvorsen B, Hol J, Øie E, Paulsson-Berne G, Yndestad A, Smith C, Otterdal K, Hedin U, Waehre T, Sandberg WJ, Frøland SS, Haraldsen G, Gullestad L, Damås JK, Hansson GK, Aukrust P (2008)
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins
Arterioscler Thromb Vasc Biol, 28 (5), 1005-11
DOI 10.1161/ATVBAHA.108.162305, PubMed 18276907

Dahl CP, Gullestad L, Fevang B, Holm AM, Landrø L, Vinge LE, Fiane AE, Sandberg WJ, Otterdal K, Frøland SS, Damås JK, Halvorsen B, Aukrust P, Øie E, Yndestad A (2008)
Increased expression of LIGHT/TNFSF14 and its receptors in experimental and clinical heart failure
Eur J Heart Fail, 10 (4), 352-9
DOI 10.1016/j.ejheart.2008.02.010, PubMed 18353719

Halvorsen B, Otterdal K, Dahl TB, Skjelland M, Gullestad L, Øie E, Aukrust P (2008)
Atherosclerotic plaque stability--what determines the fate of a plaque?
Prog Cardiovasc Dis, 51 (3), 183-94
DOI 10.1016/j.pcad.2008.09.001, PubMed 19026853

Halvorsen B, Otterdal K, Tonstad S, Aukrust P (2008)
Smoking and Inflammation: Their Synergistic Roles in Chronic Disease
Curr. Cardiovascu. Risk Rep., 2 (6), 446-451
DOI 10.1007/s12170-008-0079-z

Handberg A, Skjelland M, Michelsen AE, Sagen EL, Krohg-Sørensen K, Russell D, Dahl A, Ueland T, Oie E, Aukrust P, Halvorsen B (2008)
Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instability
Stroke, 39 (11), 3092-5
DOI 10.1161/STROKEAHA.108.517128, PubMed 18723424

Holven KB, Aukrust P, Retterstøl K, Otterdal K, Bjerkeli V, Ose L, Nenseter MS, Halvorsen B (2008)
The antiatherogenic function of HDL is impaired in hyperhomocysteinemic subjects
J Nutr, 138 (11), 2070-5
DOI 10.3945/jn.108.090704, PubMed 18936200

Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Frøland SS, Olofsson PS, Damås JK, Gullestad L, Hansson GK, Oie E, Aukrust P (2008)
Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis
Circ Res, 104 (1), 60-8
DOI 10.1161/CIRCRESAHA.108.188078, PubMed 19023130

Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Frøland SS, Oie E, Gullestad L, Damås JK, Aukrust P (2008)
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins
Cardiovasc Res, 79 (1), 195-203
DOI 10.1093/cvr/cvn071, PubMed 18339644

Publications 2007

Dahl TB, Yndestad A, Skjelland M, Øie E, Dahl A, Michelsen A, Damås JK, Tunheim SH, Ueland T, Smith C, Bendz B, Tonstad S, Gullestad L, Frøland SS, Krohg-Sørensen K, Russell D, Aukrust P, Halvorsen B (2007)
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization
Circulation, 115 (8), 972-80
DOI 10.1161/CIRCULATIONAHA.106.665893, PubMed 17283255

Halvorsen B, Lund Sagen E, Ueland T, Aukrust P, Tonstad S (2007)
Effect of smoking cessation on markers of inflammation and endothelial cell activation among individuals with high risk for cardiovascular disease
Scand J Clin Lab Invest, 67 (6), 604-11
DOI 10.1080/00365510701283878, PubMed 17852807

Sikkeland LI, Haug T, Stangeland AM, Flatberg G, Søstrand P, Halvorsen B, Kongerud J (2007)
Airway inflammation in paper mill workers
J Occup Environ Med, 49 (10), 1135-42
DOI 10.1097/JOM.0b013e31814b2e87, PubMed 18000418

Skjelland M, Michelsen AE, Krohg-Sørensen K, Tennøe B, Dahl A, Bakke S, Brosstad F, Damås JK, Russell D, Halvorsen B, Aukrust P (2007)
Plasma levels of granzyme B are increased in patients with lipid-rich carotid plaques as determined by echogenicity
Atherosclerosis, 195 (2), e142-6
DOI 10.1016/j.atherosclerosis.2007.05.001, PubMed 17568588

Publications 2006

Damås JK, Smith C, Øie E, Fevang B, Halvorsen B, Waehre T, Boullier A, Breland U, Yndestad A, Ovchinnikova O, Robertson AK, Sandberg WJ, Kjekshus J, Taskén K, Frøland SS, Gullestad L, Hansson GK, Quehenberger O, Aukrust P (2006)
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Arterioscler Thromb Vasc Biol, 27 (3), 614-20
DOI 10.1161/01.ATV.0000255581.38523.7c, PubMed 17170367

Dyrøy E, Røst TH, Pettersen RJ, Halvorsen B, Gudbrandsen OA, Ueland T, Muna Z, Müller F, Nordrehaug JE, Aukrust P, Berge RK (2006)
Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties
Arterioscler Thromb Vasc Biol, 27 (3), 628-34
DOI 10.1161/01.ATV.0000255950.70774.d5, PubMed 17185614

Florholmen G, Halvorsen B, Beraki K, Lyberg T, Sagen EL, Aukrust P, Christensen G, Yndestad A (2006)
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J Mol Cell Cardiol, 41 (4), 689-97
DOI 10.1016/j.yjmcc.2006.07.009, PubMed 16926021

Halvorsen B, Waehre T, Scholz H, Damås JK, Yndestad A, Aukrust P (2006)
Role of interleukin-10 in atherogenesis and plaque stabilization
Future Cardiol, 2 (1), 75-83
DOI 10.2217/14796678.2.1.75, PubMed 19804134

Holm T, Ueland T, Halvorsen B, Hognestad A, Holm AG, Wergeland R, Gullestad L, Aukrust P, Kjekshus J (2006)
A protective anti-inflammatory phenotype in high-risk individuals who do not develop coronary artery disease
J Am Coll Cardiol, 47 (5), 1085-6
DOI 10.1016/j.jacc.2005.11.042, PubMed 16516099

Holven KB, Halvorsen B, Bjerkeli V, Damås JK, Retterstøl K, Mørkrid L, Ose L, Aukrust P, Nenseter MS (2006)
Impaired inhibitory effect of interleukin-10 on the balance between matrix metalloproteinase-9 and its inhibitor in mononuclear cells from hyperhomocysteinemic subjects
Stroke, 37 (7), 1731-6
DOI 10.1161/01.STR.0000226465.84561.cb, PubMed 16728689

Ottestad IO, Halvorsen B, Balstad TR, Otterdal K, Borge GI, Brosstad F, Myhre AM, Ose L, Nenseter MS, Holven KB (2006)
Triglyceride-rich HDL3 from patients with familial hypercholesterolemia are less able to inhibit cytokine release or to promote cholesterol efflux
J Nutr, 136 (4), 877-81
DOI 10.1093/jn/136.4.877, PubMed 16549444

Ranheim T, Halvorsen B (2006)
[Lox-1--an actor in cardiovascular disease?]
Tidsskr Nor Laegeforen, 126 (6), 753-5
PubMed 16541167

Sandberg WJ, Yndestad A, Øie E, Smith C, Ueland T, Ovchinnikova O, Robertson AK, Müller F, Semb AG, Scholz H, Andreassen AK, Gullestad L, Damås JK, Frøland SS, Hansson GK, Halvorsen B, Aukrust P (2006)
Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
Arterioscler Thromb Vasc Biol, 26 (4), 857-63
DOI 10.1161/01.ATV.0000204334.48195.6a, PubMed 16424351

Smith C, Damås JK, Otterdal K, Øie E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Frøland SS, Hansson GK, Aukrust P (2006)
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation
J Am Coll Cardiol, 48 (8), 1591-9
DOI 10.1016/j.jacc.2006.06.060, PubMed 17045893

Publications 2005

Aukrust P, Yndestad A, Smith C, Sandberg WJ, Ueland T, Waehre T, Halvorsen B, Gullestad L, Damås JK (2005)
Potential role for immunomodulatory therapy in atherosclerotic plaque stabilisation
Expert Opin Pharmacother, 6 (13), 2169-80
DOI 10.1517/14656566.6.13.2169, PubMed 16218879

Aukrust P, Yndestad A, Waehre T, Gullestad L, Halvorsen B, Damås JK (2005)
Inflammation in coronary artery disease: potential role for immunomodulatory therapy
Expert Rev Cardiovasc Ther, 3 (6), 1111-24
DOI 10.1586/14779072.3.6.1111, PubMed 16293001

Balstad TR, Holven KB, Ottestad IO, Otterdal K, Halvorsen B, Myhre AM, Ose L, Nenseter MS (2005)
Altered composition of HDL3 in FH subjects causing a HDL subfraction with less atheroprotective function
Clin Chim Acta, 359 (1-2), 171-8
DOI 10.1016/j.cccn.2005.03.050, PubMed 15936009

Dyrøy E, Yndestad A, Ueland T, Halvorsen B, Damås JK, Aukrust P, Berge RK (2005)
Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways
Arterioscler Thromb Vasc Biol, 25 (7), 1364-9
DOI 10.1161/01.ATV.0000171982.57713.96, PubMed 15920037

Glosli H, Gudbrandsen OA, Mullen AJ, Halvorsen B, Røst TH, Wergedahl H, Prydz H, Aukrust P, Berge RK (2005)
Down-regulated expression of PPARalpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNFalpha
Biochim Biophys Acta, 1734 (3), 235-46
DOI 10.1016/j.bbalip.2005.02.011, PubMed 15893958

Gurantz D, Yndestad A, Halvorsen B, Lunde OV, Omens JH, Ueland T, Aukrust P, Moore CD, Kjekshus J, Greenberg BH (2005)
Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling
Cardiovasc Res, 67 (1), 106-15
DOI 10.1016/j.cardiores.2005.02.016, PubMed 15949474

Holven KB, Damås JK, Yndestad A, Waehre T, Ueland T, Halvorsen B, Heggelund L, Sandberg WJ, Semb AG, Frøland SS, Ose L, Nenseter MS, Aukrust P (2005)
Chemokines in children with heterozygous familiar hypercholesterolemia: selective upregulation of RANTES
Arterioscler Thromb Vasc Biol, 26 (1), 200-5
DOI 10.1161/01.ATV.0000193619.67288.ed, PubMed 16254204

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Lømo J, Rivera S, Khrestchatisky M, Halvorsen B, Saugstad OD (2005)
Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8
Pediatr Res, 58 (3), 542-8
DOI 10.1203/01.PDR.0000179407.46810.2D, PubMed 16148071

Ranheim T, Halvorsen B (2005)
Coffee consumption and human health--beneficial or detrimental?--Mechanisms for effects of coffee consumption on different risk factors for cardiovascular disease and type 2 diabetes mellitus
Mol Nutr Food Res, 49 (3), 274-84
DOI 10.1002/mnfr.200400109, PubMed 15704241

Scholz H, Sandberg W, Damås JK, Smith C, Andreassen AK, Gullestad L, Frøland SS, Yndestad A, Aukrust P, Halvorsen B (2005)
Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis
Circulation, 112 (14), 2121-9
DOI 10.1161/CIRCULATIONAHA.105.544676, PubMed 16186421

Torheim EA, Yndestad A, Bjerkeli V, Halvorsen B, Aukrust P, Frøland SS (2005)
Increased expression of chemokines in patients with Wegener's granulomatosis - modulating effects of methylprednisolone in vitro
Clin Exp Immunol, 140 (2), 376-83
DOI 10.1111/j.1365-2249.2005.02770.x, PubMed 15807865

Ueland T, Yndestad A, Øie E, Florholmen G, Halvorsen B, Frøland SS, Simonsen S, Christensen G, Gullestad L, Aukrust P (2005)
Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-8
DOI 10.1161/01.CIR.0000165119.62099.14, PubMed 15883214

Publications 2004

Bjerkeli V, Halvorsen B, Damås JK, Nordøy I, Yndestad A, Aukrust P, Frøland SS (2004)
Expression of matrix metalloproteinases in patients with Wegener's granulomatosis
Ann Rheum Dis, 63 (12), 1659-63
DOI 10.1136/ard.2003.017954, PubMed 15547092

Borke WB, Munkeby BH, Halvorsen B, Bjornland K, Tunheim SH, Borge GI, Thaulow E, Saugstad OD (2004)
Increased myocardial matrix metalloproteinases in hypoxic newborn pigs during resuscitation: effects of oxygen and carbon dioxide
Eur J Clin Invest, 34 (7), 459-66
DOI 10.1111/j.1365-2362.2004.01378.x, PubMed 15255782

Fredriksen J, Ueland T, Dyrøy E, Halvorsen B, Melby K, Melbye L, Skalhegg BS, Bohov P, Skorve J, Berge RK, Aukrust P, Frøland SS (2004)
Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy
Eur J Clin Invest, 34 (10), 709-15
DOI 10.1111/j.1365-2362.2004.01410.x, PubMed 15473896

Halvorsen B, Waehre T, Scholz H, Clausen OP, von der Thüsen JH, Müller F, Heimli H, Tonstad S, Hall C, Frøland SS, Biessen EA, Damås JK, Aukrust P (2004)
Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms
J Lipid Res, 46 (2), 211-9
DOI 10.1194/jlr.M400324-JLR200, PubMed 15547296

Holm AM, Aukrust P, Damås JK, Müller F, Halvorsen B, Frøland SS (2004)
Abnormal interleukin-7 function in common variable immunodeficiency
Blood, 105 (7), 2887-90
DOI 10.1182/blood-2004-06-2423, PubMed 15598813

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Halvorsen B, Saugstad OD (2004)
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets
Pediatr Res, 56 (5), 783-90
DOI 10.1203/01.PDR.0000141988.89820.E3, PubMed 15347772

Scholz H, Aukrust P, Damås JK, Tonstad S, Sagen EL, Kolset SO, Hall C, Yndestad A, Halvorsen B (2004)
8-isoprostane increases scavenger receptor A and matrix metalloproteinase activity in THP-1 macrophages, resulting in long-lived foam cells
Eur J Clin Invest, 34 (7), 451-8
DOI 10.1111/j.1365-2362.2004.01376.x, PubMed 15255781

Smith C, Yndestad A, Halvorsen B, Ueland T, Waehre T, Otterdal K, Scholz H, Endresen K, Gullestad L, Frøland SS, Damås JK, Aukrust P (2004)
Potential anti-inflammatory role of activin A in acute coronary syndromes
J Am Coll Cardiol, 44 (2), 369-75
DOI 10.1016/j.jacc.2004.03.069, PubMed 15261933

Waehre T, Damås JK, Yndestad A, Taskén K, Pedersen TM, Smith C, Halvorsen B, Frøland SS, Solum NO, Aukrust P (2004)
Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells - potential role of prostaglandin E2
Thromb Haemost, 92 (6), 1358-67
DOI 10.1160/TH04-03-0146, PubMed 15583745

Yndestad A, Ueland T, Øie E, Florholmen G, Halvorsen B, Attramadal H, Simonsen S, Frøland SS, Gullestad L, Christensen G, Damås JK, Aukrust P (2004)
Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
DOI 10.1161/01.CIR.0000120704.97934.41, PubMed 14993131

Publications 2003

Holven KB, Halvorsen B, Schulz H, Aukrust P, Ose L, Nenseter MS (2003)
Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects
Eur J Clin Invest, 33 (7), 555-60
DOI 10.1046/j.1365-2362.2003.01189.x, PubMed 12814391

Holven KB, Scholz H, Halvorsen B, Aukrust P, Ose L, Nenseter MS (2003)
Hyperhomocysteinemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells
J Nutr, 133 (11), 3588-91
DOI 10.1093/jn/133.11.3588, PubMed 14608078

Scholz H, Yndestad A, Damås JK, Waehre T, Tonstad S, Aukrust P, Halvorsen B (2003)
8-isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases
Cardiovasc Res, 59 (4), 945-54
DOI 10.1016/s0008-6363(03)00538-8, PubMed 14553834

Staff AC, Halvorsen B (2003)
[Isoprostanes--new markers of oxidative stress]
Tidsskr Nor Laegeforen, 123 (3), 315-8
PubMed 12640897

Staff AC, Ranheim T, Halvorsen B (2003)
Augmented PLA2 activity in pre-eclamptic decidual tissue--a key player in the pathophysiology of 'acute atherosis' in pre-eclampsia?
Placenta, 24 (10), 965-73
DOI 10.1016/s0143-4004(03)00175-9, PubMed 14580379

Publications 2002

Damås JK, Waehre T, Yndestad A, Ueland T, Müller F, Eiken HG, Holm AM, Halvorsen B, Frøland SS, Gullestad L, Aukrust P (2002)
Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects
Circulation, 106 (1), 36-42
DOI 10.1161/01.cir.0000020001.09990.90, PubMed 12093767

Waehre T, Halvorsen B, Damås JK, Yndestad A, Brosstad F, Gullestad L, Kjekshus J, Frøland SS, Aukrust P (2002)
Inflammatory imbalance between IL-10 and TNFalpha in unstable angina potential plaque stabilizing effects of IL-10
Eur J Clin Invest, 32 (11), 803-10
DOI 10.1046/j.1365-2362.2002.01069.x, PubMed 12423320

Publications 2001

Halvorsen B, Rustan AC, Madsen L, Reseland J, Berge RK, Sletnes P, Christiansen EN (2001)
Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats
Ann Nutr Metab, 45 (1), 30-7
DOI 10.1159/000046703, PubMed 11244185

Halvorsen B, Staff AC, Henriksen T, Sawamura T, Ranheim T (2001)
8-iso-prostaglandin F(2alpha) increases expression of LOX-1 in JAR cells
Hypertension, 37 (4), 1184-90
DOI 10.1161/01.hyp.37.4.1184, PubMed 11304522

Reseland JE, Haugen F, Hollung K, Solvoll K, Halvorsen B, Brude IR, Nenseter MS, Christiansen EN, Drevon CA (2001)
Reduction of leptin gene expression by dietary polyunsaturated fatty acids
J Lipid Res, 42 (5), 743-50
PubMed 11352981

Publications 2000

Halvorsen B, Staff AC, Ligaarden S, Prydz K, Kolset SO (2000)
Lithocholic acid and sulphated lithocholic acid differ in the ability to promote matrix metalloproteinase secretion in the human colon cancer cell line CaCo-2
Biochem J, 349 (Pt 1), 189-93
DOI 10.1042/0264-6021:3490189, PubMed 10861227

Staff AC, Ranheim T, Henriksen T, Halvorsen B (2000)
8-Iso-prostaglandin f(2alpha) reduces trophoblast invasion and matrix metalloproteinase activity
Hypertension, 35 (6), 1307-13
DOI 10.1161/01.hyp.35.6.1307, PubMed 10856282

Publications 1999

Hagen E, Myhre AM, Smeland S, Halvorsen B, Norum KR, Blomhoff R (1999)
Uptake of vitamin A in macrophages from physiologic transport proteins: role of retinol-binding protein and chylomicron remnants
J Nutr Biochem, 10 (6), 345-52
DOI 10.1016/s0955-2863(99)00013-3, PubMed 15539309

Halvorsen B, Kase BF, Prydz K, Garagozlian S, Andresen MS, Kolset SO (1999)
Sulphation of lithocholic acid in the colon-carcinoma cell line CaCo-2
Biochem J, 343 Pt 3 (Pt 3), 533-9
DOI 10.1042/0264-6021:3430533, PubMed 10527930

Staff AC, Halvorsen B, Ranheim T, Henriksen T (1999)
Elevated level of free 8-iso-prostaglandin F2alpha in the decidua basalis of women with preeclampsia
Am J Obstet Gynecol, 181 (5 Pt 1), 1211-5
DOI 10.1016/s0002-9378(99)70110-9, PubMed 10561647

Publications 1998

Halvorsen B, Ranheim T, Nenseter MS, Huggett AC, Drevon CA (1998)
Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts
J Lipid Res, 39 (4), 901-12
PubMed 9555953

Halvorsen B, Aas UK, Kulseth MA, Drevon CA, Christiansen EN, Kolset SO (1998)
Proteoglycans in macrophages: characterization and possible role in the cellular uptake of lipoproteins
Biochem J, 331 ( Pt 3) (Pt 3), 743-52
DOI 10.1042/bj3310743, PubMed 9560300

Publications 1997

Brude IR, Drevon CA, Hjermann I, Seljeflot I, Lund-Katz S, Saarem K, Sandstad B, Solvoll K, Halvorsen B, Arnesen H, Nenseter MS (1997)
Peroxidation of LDL from combined-hyperlipidemic male smokers supplied with omega-3 fatty acids and antioxidants
Arterioscler Thromb Vasc Biol, 17 (11), 2576-88
DOI 10.1161/01.atv.17.11.2576, PubMed 9409230

Rustan AC, Halvorsen B, Huggett AC, Ranheim T, Drevon CA (1997)
Effect of coffee lipids (cafestol and kahweol) on regulation of cholesterol metabolism in HepG2 cells
Arterioscler Thromb Vasc Biol, 17 (10), 2140-9
DOI 10.1161/01.atv.17.10.2140, PubMed 9351383

Rustan AC, Halvorsen B, Ranheim T, Drevon CA (1997)
Cafestol (a coffee lipid) decreases uptake of low-density lipoprotein (LDL) in human skin fibroblasts and liver cells
Ann N Y Acad Sci, 827, 158-62
DOI 10.1111/j.1749-6632.1997.tb51830.x, PubMed 9329750

Publications 1996

Halvorsen B (1996)
Metabolism of low density lipoprotein: relation to certain nutrients, drugs, and proteoglycans
Institute for Nutrition Research, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 961573198, ISBN 82-992681-4-1

Halvorsen B, Almendingen K, Nenseter MS, Pedersen JI, Christiansen EN (1996)
Effects of partially hydrogenated fish oil, partially hydrogenated soybean oil and butter on the susceptibility of low density lipoprotein to oxidative modification in men
Eur J Clin Nutr, 50 (6), 364-70
PubMed 8793417

Halvorsen B, Brude I, Drevon CA, Nysom J, Ose L, Christiansen EN, Nenseter MS (1996)
Effect of homocysteine on copper ion-catalyzed, azo compound-initiated, and mononuclear cell-mediated oxidative modification of low density lipoprotein
J Lipid Res, 37 (7), 1591-600
PubMed 8827529

Mathiesen L, Wang S, Halvorsen B, Malterud KE, Sund RB (1996)
Inhibition of lipid peroxidation in low-density lipoprotein by the flavonoid myrigalone B and ascorbic acid
Biochem Pharmacol, 51 (12), 1719-25
DOI 10.1016/0006-2952(96)00107-4, PubMed 8687487

Publications 1995

Halvorsen B, Rustan AC, Christiansen EN (1995)
Effect of long-chain mono-unsaturated and n-3 polyunsaturated fatty acids on postprandial blood and liver lipids in rats
Scand J Clin Lab Invest, 55 (6), 469-75
DOI 10.1080/00365519509075384, PubMed 8571076

Nenseter MS, Halvorsen B, Rosvold O, Rustan AC, Drevon CA (1995)
Paracetamol inhibits copper ion-induced, azo compound-initiated, and mononuclear cell-mediated oxidative modification of LDL
Arterioscler Thromb Vasc Biol, 15 (9), 1338-44
DOI 10.1161/01.atv.15.9.1338, PubMed 7670947

Ranheim T, Halvorsen B, Huggett AC, Blomhoff R, Drevon CA (1995)
Effect of a coffee lipid (cafestol) on regulation of lipid metabolism in CaCo-2 cells
J Lipid Res, 36 (10), 2079-89
PubMed 8576635

Publications 1993

Myrset AH, Halvorsen B, Ording E, Helgeland L (1993)
The time courses of intracellular transport of some secretory proteins of rat liver are not affected by an induced acute phase response
Eur J Cell Biol, 60 (1), 108-14
PubMed 8462589

Publications 1992

Halvorsen B (1992)
Intracellulær transport av sekretoriske proteiner under indusert akutt inflammasjon i rotte
[B. Halvorsen], Oslo, 134 bl.
BIBSYS 921048408