Publications 2024

Alkaltham MF, Almansour AI, Arumugam N, Vagolu SK, Tønjum T, Alaqeel SI, Rajaratnam S, Sivaramakrishnan V (2024)
Activity against Mycobacterium tuberculosis of a new class of spirooxindolopyrrolidine embedded chromanone hybrid heterocycles
RSC Adv, 14 (17), 11604-11613
DOI 10.1039/d4ra01501k, PubMed 38605893

Girase RT, Ahmad I, Oh JM, Mathew B, Vagolu SK, Tønjum T, Sriram D, Kumari J, Desai NC, Agrawal Y, Kim H, Patel HM (2024)
Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
ACS Med Chem Lett, 15 (6), 924-937
DOI 10.1021/acsmedchemlett.4c00114, PubMed 38894926

Publications 2023

Chaw Pattnayak B, Krishna VS, Sahu BK, Mohapatra S (2023)
Reusable Floating Spherical Hydrogel Evaporator for Solar Desalination with Salt Mitigation and Contaminant Elimination
Langmuir, 39 (50), 18663-18671
DOI 10.1021/acs.langmuir.3c03174, PubMed 38063076

Girase RT, Ahmad I, Oh JM, Kim H, Mathew B, Vagolu SK, Tønjum T, Desai NC, Sriram D, Kumari J, Patel HM (2023)
Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis
ACS Med Chem Lett, 14 (12), 1754-1759
DOI 10.1021/acsmedchemlett.3c00406, PubMed 38116435

Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F (2023)
Design, Synthesis, and Evaluation of Novel Δ²-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant
J Med Chem, 66 (16), 11056-11077
DOI 10.1021/acs.jmedchem.3c00358, PubMed 37485869

Özcan E, Vagolu SK, Gündüz MG, Stevanovic M, Kökbudak Z, Tønjum T, Nikodinovic-Runic J, Çetinkaya Y, Doğan ŞD (2023)
Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities
ACS Omega, 8 (43), 40140-40152
DOI 10.1021/acsomega.3c03018, PubMed 37929089

Publications 2022

Dhameliya TM, Tiwari R, Patel KI, Vagolu SK, Panda D, Sriram D, Chakraborti AK (2022)
Bacterial FtsZ inhibition by benzo[d]imidazole-2-carboxamide derivative with anti-TB activity
Future Med Chem, 14 (19), 1361-1373
DOI 10.4155/fmc-2022-0120, PubMed 36103222

Keleş Atıcı R, Doğan ŞD, Gündüz MG, Krishna VS, Chebaiki M, Homberset H, Lherbet C, Mourey L, Tønjum T (2022)
Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities
Drug Dev Res, 83 (6), 1292-1304
DOI 10.1002/ddr.21958, PubMed 35769019

Koçak Aslan E, Han Mİ, Krishna VS, Tamhaev R, Dengiz C, Doğan ŞD, Lherbet C, Mourey L, Tønjum T, Gündüz MG (2022)
Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity
Pharmaceuticals (Basel), 15 (10)
DOI 10.3390/ph15101301, PubMed 36297413

Koçak Aslan E, Vagolu SK, Armakovic SJ, Armakovic S, Sahin O, Tønjum T, Gündüz MG (2022)
Linking azoles to isoniazid via hydrazone bridge: Synthesis, crystal structure determination, antitubercular evaluation and computational studies
Journal of Molecular Liquids, 354, 118873
DOI 10.1016/j.molliq.2022.118873, PublikaID 422

Tapera M, Kekeçmuhammed H, Sahin K, Vagolu SK, Lherbet C, Homberset H, Chebaiki M, Tønjum T, Mourey L, Zorlu Y, Durdagi S, Sarıpınar E (2022)
Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety
Journal of Molecular Structure, 1270, 133899
DOI 10.1016/j.molstruc.2022.133899, PublikaID 421

Publications 2021

Karale UB, Shinde AU, Babar DA, Sangu KG, Vagolu SK, Eruva VK, Jadav SS, Misra S, Dharmarajan S, Rode HB (2021)
3-Aryl-substituted imidazo[1,2-a]pyridines as antituberculosis agents
Arch Pharm (Weinheim), 354 (10), e2000419
DOI 10.1002/ardp.202000419, PubMed 34185337

Konduri S, Bhargavi D, Prashanth J, Krishna VS, Sriram D, Rao KP (2021)
Design and Synthesis of "Chloropicolinate Amides and Urea Derivatives" as Novel Inhibitors for Mycobacterium tuberculosis
ACS Omega, 6 (2), 1657-1667
DOI 10.1021/acsomega.0c05690, PubMed 33490825

Murthy VS, Tamboli Y, Krishna VS, Sriram D, Akber Ansari S, Alarfaj AA, Hirad AH, Vijayakumar V (2021)
Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors
J Enzyme Inhib Med Chem, 36 (1), 1751-1759
DOI 10.1080/14756366.2021.1956914, PubMed 34325595

Murthy VS, Tamboli Y, Krishna VS, Sriram D, Zhang FX, Zamponi GW, Vijayakumar V (2021)
Synthesis and Biological Evaluation of Novel Benzhydrylpiperazine-Coupled Nitrobenzenesulfonamide Hybrids
ACS Omega, 6 (14), 9731-9740
DOI 10.1021/acsomega.1c00369, PubMed 33869953

Publications 2020

Arumugam N, Almansour AI, Kumar RS, Mohammad Ali Al-Aizari AJ, Alaqeel SI, Kansız S, Krishna VS, Sriram D, Dege N (2020)
Regio- and diastereoselective synthesis of spiropyrroloquinoxaline grafted indole heterocyclic hybrids and evaluation of their anti-Mycobacterium tuberculosis activity
RSC Adv, 10 (40), 23522-23531
DOI 10.1039/d0ra02525a, PubMed 35517328

Aziz HA, Moustafa GAI, Abuo-Rahma GEA, Rabea SM, Hauk G, Krishna VS, Sriram D, Berger JM, Abbas SH (2020)
Synthesis and antimicrobial evaluation of new nitric oxide-donating fluoroquinolone/oxime hybrids
Arch Pharm (Weinheim), 354 (1), e2000180
DOI 10.1002/ardp.202000180, PubMed 32959443

Bangalore PK, Vagolu SK, Bollikanda RK, Veeragoni DK, Choudante PC, Misra S, Sriram D, Sridhar B, Kantevari S (2020)
Correction to Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents
J Nat Prod, 83 (10), 3214
DOI 10.1021/acs.jnatprod.0c01005, PubMed 32960607

Dhameliya TM, Patel KI, Tiwari R, Vagolu SK, Panda D, Sriram D, Chakraborti AK (2020)
Design, synthesis, and biological evaluation of benzo[d]imidazole-2-carboxamides as new anti-TB agents
Bioorg Chem, 107, 104538
DOI 10.1016/j.bioorg.2020.104538, PubMed 33349456

Dogamanti A, Chiranjeevi P, Aamate VK, Vagolu SK, Sriram D, Balasubramanian S, Sarasija M (2020)
Indole-fused spirochromenes as potential anti-tubercular agents: design, synthesis and in vitro evaluation
Mol Divers, 25 (4), 2137-2148
DOI 10.1007/s11030-020-10108-z, PubMed 32474889

Doğan H, Doğan ŞD, Gündüz MG, Krishna VS, Lherbet C, Sriram D, Şahin O, Sarıpınar E (2020)
Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
Eur J Med Chem, 188, 112035
DOI 10.1016/j.ejmech.2020.112035, PubMed 31951850

Doğan ŞD, Gündüz MG, Doğan H, Krishna VS, Lherbet C, Sriram D (2020)
Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors
Eur J Med Chem, 199, 112402
DOI 10.1016/j.ejmech.2020.112402, PubMed 32417538

Gaikwad VR, Karale UB, Govindarajalu G, Adhikari N, Krishna EV, Krishna VS, Misra S, Sriram D, Sijwali PS, Rode HB (2020)
Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens
Bioorg Med Chem Lett, 30 (8), 127037
DOI 10.1016/j.bmcl.2020.127037, PubMed 32081449

Gündüz MG, Uğur SB, Güney F, Özkul C, Krishna VS, Kaya S, Sriram D, Doğan ŞD (2020)
1,3-Disubstituted urea derivatives: Synthesis, antimicrobial activity evaluation and in silico studies
Bioorg Chem, 102, 104104
DOI 10.1016/j.bioorg.2020.104104, PubMed 32736149

Jadhavar PS, Patel KI, Dhameliya TM, Saha N, Vaja MD, Krishna VS, Sriram D, Chakraborti AK (2020)
Benzimidazoquinazolines as new potent anti-TB chemotypes: Design, synthesis, and biological evaluation
Bioorg Chem, 99, 103774
DOI 10.1016/j.bioorg.2020.103774, PubMed 32224336

Jogula S, Krishna VS, Meda N, Balraju V, Sriram D (2020)
Design, synthesis and biological evaluation of novel Pseudomonas aeruginosa DNA gyrase B inhibitors
Bioorg Chem, 100, 103905
DOI 10.1016/j.bioorg.2020.103905, PubMed 32388436

Konduri S, Prashanth J, Krishna VS, Sriram D, Behera JN, Siegel D, Rao KP (2020)
Design and synthesis of purine connected piperazine derivatives as novel inhibitors of Mycobacterium tuberculosis
Bioorg Med Chem Lett, 30 (22), 127512
DOI 10.1016/j.bmcl.2020.127512, PubMed 32871269

Krishna VS, Zheng S, Rekha EM, Nallangi R, Sai Prasad DV, George SE, Guddat LW, Sriram D (2020)
Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors
Eur J Med Chem, 193, 112178
DOI 10.1016/j.ejmech.2020.112178, PubMed 32171154

Marvadi SK, Krishna VS, Surineni G, Srilakshmi Reshma R, Sridhar B, Sriram D, Kantevari S (2020)
Synthesis, in vitro, and in vivo (Zebra fish) antitubercular activity of 7,8-dihydroquinolin-5(6H)-ylidenehydrazinecarbothioamides
Bioorg Chem, 96, 103626
DOI 10.1016/j.bioorg.2020.103626, PubMed 32007719

Phatak PS, Bakale RD, Kulkarni RS, Dhumal ST, Dixit PP, Krishna VS, Sriram D, Khedkar VM, Haval KP (2020)
Design and synthesis of new indanol-1,2,3-triazole derivatives as potent antitubercular and antimicrobial agents
Bioorg Med Chem Lett, 30 (22), 127579
DOI 10.1016/j.bmcl.2020.127579, PubMed 32987135

Publications 2019

Akolkar SV, Nagargoje AA, Krishna VS, Sriram D, Sangshetti JN, Damale M, Shingate BB (2019)
New N-phenylacetamide-incorporated 1,2,3-triazoles: [Et₃NH][OAc]-mediated efficient synthesis and biological evaluation
RSC Adv, 9 (38), 22080-22091
DOI 10.1039/c9ra03425k, PubMed 35518861

Bangalore PK, Vagolu SK, Bollikanda RK, Veeragoni DK, Choudante PC, Misra S, Sriram D, Sridhar B, Kantevari S (2019)
Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents
J Nat Prod, 83 (1), 26-35
DOI 10.1021/acs.jnatprod.9b00475, PubMed 31858800

Karale UB, Krishna VS, Krishna EV, Choudhari AS, Shukla M, Gaikwad VR, Mahizhaveni B, Chopra S, Misra S, Sarkar D, Sriram D, Dusthackeer VNA, Rode HB (2019)
Synthesis and biological evaluation of 2,4,5-trisubstituted thiazoles as antituberculosis agents effective against drug-resistant tuberculosis
Eur J Med Chem, 178, 315-328
DOI 10.1016/j.ejmech.2019.05.082, PubMed 31195172

Krishna VS, Zheng S, Rekha EM, Guddat LW, Sriram D (2019)
Discovery and evaluation of novel Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors as therapeutic drug leads
J Comput Aided Mol Des, 33 (3), 357-366
DOI 10.1007/s10822-019-00184-1, PubMed 30666485

Makane VB, Krishna VS, Krishna EV, Shukla M, Mahizhaveni B, Misra S, Chopra S, Sriram D, Azger Dusthackeer VN, Rode HB (2019)
Novel 1,3,4-oxadiazoles as antitubercular agents with limited activity against drug-resistant tuberculosis
Future Med Chem, 11 (6), 499-510
DOI 10.4155/fmc-2018-0378, PubMed 30892944

Makane VB, Krishna VS, Krishna EV, Shukla M, Mahizhaveni B, Misra S, Chopra S, Sriram D, Dusthackeer VNA, Rode HB (2019)
Synthesis and evaluation of α-aminoacyl amides as antitubercular agents effective on drug resistant tuberculosis
Eur J Med Chem, 164, 665-677
DOI 10.1016/j.ejmech.2019.01.002, PubMed 30654238

Marvadi SK, Krishna VS, Sinegubova EO, Volobueva AS, Esaulkova YL, Muryleva AA, Tentler DG, Sriram D, Zarubaev VV, Kantevari S (2019)
5-Chloro-2-thiophenyl-1,2,3-triazolylmethyldihydroquinolines as dual inhibitors of Mycobacterium tuberculosis and influenza virus: Synthesis and evaluation
Bioorg Med Chem Lett, 29 (18), 2664-2669
DOI 10.1016/j.bmcl.2019.07.040, PubMed 31375291

Marvadi SK, Krishna VS, Sriram D, Kantevari S (2019)
Synthesis and evaluation of novel substituted 1,2,3-triazolyldihydroquinolines as promising antitubercular agents
Bioorg Med Chem Lett, 29 (4), 529-533
DOI 10.1016/j.bmcl.2019.01.004, PubMed 30638877

Pogaku V, Krishna VS, Sriram D, Rangan K, Basavoju S (2019)
Ultrasonication-ionic liquid synergy for the synthesis of new potent anti-tuberculosis 1,2,4-triazol-1-yl-pyrazole based spirooxindolopyrrolizidines
Bioorg Med Chem Lett, 29 (13), 1682-1687
DOI 10.1016/j.bmcl.2019.04.026, PubMed 31047752

Sharma K, Tanwar O, Deora GS, Ali S, Alam MM, Zaman MS, Krishna VS, Sriram D, Akhter M (2019)
Expansion of a novel lead targeting M. tuberculosis DHFR as antitubercular agents
Bioorg Med Chem, 27 (7), 1421-1429
DOI 10.1016/j.bmc.2019.02.053, PubMed 30827867

Sirim MM, Krishna VS, Sriram D, Unsal Tan O (2019)
Novel benzimidazole-acrylonitrile hybrids and their derivatives: Design, synthesis and antimycobacterial activity
Eur J Med Chem, 188, 112010
DOI 10.1016/j.ejmech.2019.112010, PubMed 31893548

Türe A, Kulabaş N, Dingiş Sİ, Birgül K, Bozdeveci A, Alpay Karaoğlu Ş, Krishna VS, Sriram D, Küçükgüzel İ (2019)
Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents
Bioorg Chem, 88, 102965
DOI 10.1016/j.bioorg.2019.102965, PubMed 31085371

Publications 2018

Ashok D, Chiranjeevi P, Kumar AV, Sarasija M, Krishna VS, Sriram D, Balasubramanian S (2018)
1,2,3-Triazole-fused spirochromenes as potential anti-tubercular agents: synthesis and biological evaluation
RSC Adv, 8 (30), 16997-17007
DOI 10.1039/c8ra03197e, PubMed 35540499

Beesetti H, Tyagi P, Medapi B, Krishna VS, Sriram D, Khanna N, Swaminathan S (2018)
A quinoline compound inhibits the replication of dengue virus serotypes 1-4 in Vero cells
Antivir Ther, 23 (5), 385-394
DOI 10.3851/IMP3231, PubMed 29583121

Kumar G, Krishna VS, Sriram D, Jachak SM (2018)
Synthesis of carbohydrazides and carboxamides as anti-tubercular agents
Eur J Med Chem, 156, 871-884
DOI 10.1016/j.ejmech.2018.07.047, PubMed 30056283

Kumar G, Sathe A, Krishna VS, Sriram D, Jachak SM (2018)
Synthesis and biological evaluation of dihydroquinoline carboxamide derivatives as anti-tubercular agents
Eur J Med Chem, 157, 1-13
DOI 10.1016/j.ejmech.2018.07.046, PubMed 30064024

Malapati P, Krishna VS, Dharmarajan S (2018)
Identification and development of novel indazole derivatives as potent bacterial peptidoglycan synthesis inhibitors
Int J Mycobacteriol, 7 (1), 76-83
DOI 10.4103/ijmy.ijmy_201_17, PubMed 29516890

Mali HM, Sabale SS, Degani MS, Borkute R, Choudhari AS, Sarkar D, Krishna VS, Sriram D (2018)
Rational design of coumarin derivatives as antituberculosis agents
Future Med Chem, 10 (20), 2431-2444
DOI 10.4155/fmc-2018-0015, PubMed 30325198

Marvadi SK, Krishna VS, Sriram D, Kantevari S (2018)
Synthesis of novel morpholine, thiomorpholine and N-substituted piperazine coupled 2-(thiophen-2-yl)dihydroquinolines as potent inhibitors of Mycobacterium tuberculosis
Eur J Med Chem, 164, 171-178
DOI 10.1016/j.ejmech.2018.12.043, PubMed 30594675

Munikumar M, Krishna VS, Reddy VS, Rajeswari B, Sriram D, Rao MV (2018)
In silico design of small peptides antagonist against leptin receptor for the treatment of obesity and its associated immune-mediated diseases
J Mol Graph Model, 82, 20-36
DOI 10.1016/j.jmgm.2018.04.002, PubMed 29649778

Publications 2017

Malapati P, Krishna VS, Nallangi R, Srilakshmi RR, Sriram D (2017)
Identification and development of benzoxazole derivatives as novel bacterial glutamate racemase inhibitors
Eur J Med Chem, 145, 23-34
DOI 10.1016/j.ejmech.2017.12.088, PubMed 29310027

Vidyacharan S, Adhikari C, Krishna VS, Reshma RS, Sriram D, Sharada DS (2017)
A robust synthesis of functionalized 2H-indazoles via solid state melt reaction (SSMR) and their anti-tubercular activity
Bioorg Med Chem Lett, 27 (7), 1593-1597
DOI 10.1016/j.bmcl.2017.02.021, PubMed 28254485

Publications 2016

Krishna VS, Samanta M, Pal S, Anurag NP, Bandyopadhyay S (2016)
Light-triggered assembly-disassembly of an ordered donor-acceptor π-stack using a photoresponsive dimethyldihydropyrene π-switch
Org Biomol Chem, 14 (24), 5744-50
DOI 10.1039/c6ob00101g, PubMed 26899505

Publications 2014

Sathyanarayana Rao TS, Darshan MS, Tandon A, Raman R, Karthik KN, Saraswathi N, Das K, Harsha GT, Krishna VS, Ashok NC (2014)
Suttur study: An epidemiological study of psychiatric disorders in south Indian rural population
Indian J Psychiatry, 56 (3), 238-45
DOI 10.4103/0019-5545.140618, PubMed 25316934

Publications 2008

Sathyanarayana Rao TS, Krishna VS (2008)
Wake up call from 'Stars on the Ground'
Indian J Psychiatry, 50 (1), 2-4
DOI 10.4103/0019-5545.39749, PubMed 19771297

Publications 1999

Jha V, Sakhuja V, Gupta D, Krishna VS, Chakrabarti A, Joshi K, Sud K, Kohli HS, Gupta KL (1999)
Successful management of pulmonary tuberculosis in renal allograft recipients in a single center
Kidney Int, 56 (5), 1944-50
DOI 10.1046/j.1523-1755.1999.00746.x, PubMed 10571806

Sud K, Singh B, Krishna VS, Thennarasu K, Kohli HS, Jha V, Gupta KL, Sakhuja V (1999)
Unpredictable cyclosporin--fluconazole interaction in renal transplant recipients
Nephrol Dial Transplant, 14 (7), 1698-703
DOI 10.1093/ndt/14.7.1698, PubMed 10435879

Publications 1996

Jha V, Krishna VS, Chakrabarti A, Sharma PK, Sud K, Kohli HS, Sakhuja V (1996)
Subcutaneous phaeohyphomycosis in a renal transplant recipient: a case report and review of the literature
Am J Kidney Dis, 28 (1), 137-9
DOI 10.1016/s0272-6386(96)90143-2, PubMed 8712209