Ellen Lund Sagen

  • Senior engineer; BSc
  • +47 23 07 27 88
 

Publications 2021

Karlsen TR, Kong XY, Holm S, Quiles-Jimenez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, Ogaard JSD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjoras M, Hov JR, Halvorsen B, Gregersen I (2021)
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
Sci Rep, 11 (1), 19749
DOI 10.1038/s41598-021-98820-0

Kong XY, Huse C, Yang K, Ogaard J, Berges N, Vik ES, Nawaz MS, Quiles-Jimenez A, Abbas A, Gregersen I, Holm S, Bjerkli V, Rashidi A, Fladeby C, Suganthan R, Sagen EL, Skjelland M, Lang AN, Boe SO, Bjoras M, Aukrust P, Alseth I, Halvorsen B, Dahl TB (2021)
Endonuclease V Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration
J. Am. Heart Assoc., 10 (14), e020656
DOI 10.1161/JAHA.120.020656

Quiles-Jimenez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygard S, Scheffler K, Prins J, Van der Veer E, Ogaard JDS, Floisand Y, Jorgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023

Publications 2020

Hoel H, Ueland T, Knudsen A, Kjaer A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Troseid M (2020)
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J. Infect. Dis., 221 (4), 506-509
DOI 10.1093/infdis/jiz253

Otterdal K, Berg A, Michelsen AE, Patel S, Gregersen I, Sagen EL, Halvorsen B, Yndestad A, Ueland T, Langeland N, Aukrust P (2020)
Plasma levels of interleukin 27 in falciparum malaria is increased independently of co-infection with HIV: potential immune-regulatory role during malaria
BMC Infect. Dis., 20 (1), 65
DOI 10.1186/s12879-020-4783-8

Publications 2019

Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE, Oie E, Gullestad L, Halvorsen B, Hansen TV, Aukrust P, Dalli J, Yndestad A (2019)
Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction
EBioMedicine, 46, 264-273
DOI 10.1016/j.ebiom.2019.07.024

Ystgaard MB, Scheffler K, Suganthan R, Bjoras M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200

Publications 2018

Skarpengland T, Skjelland M, Kong XY, Skagen K, Holm S, Otterdal K, Dahl CP, Krohg-Sorensen K, Sagen EL, Bjerkeli V, Aamodt AH, Abbas A, Gregersen I, Aukrust P, Halvorsen B, Dahl TB (2018)
Increased Levels of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Ischemic Stroke and Transient Ischemic Attack
J. Am. Heart Assoc., 7 (2), e006479
DOI 10.1161/JAHA.117.006479

Publications 2017

Espada S, Stavik B, Holm S, Sagen EL, Bjerkeli V, Skjelland M, Dahl TB, Espevik T, Kanse S, Sandset PM, Skretting G, Halvorsen B (2017)
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem. Biophys. Res. Commun., 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070

Gregersen I, Sandanger O, Askevold ET, Sagen EL, Yang K, Holm S, Pedersen TM, Skjelland M, Krohg-Sorensen K, Hansen TV, Dahl TB, Otterdal K, Espevik T, Aukrust P, Yndestad A, Halvorsen B (2017)
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation
PLoS One, 12 (11), e0188387
DOI 10.1371/journal.pone.0188387

Publications 2015

Halvorsen B, Espeland MZ, Andersen GO, Yndestad A, Sagen EL, Rashidi A, Knudsen EC, Skjelland M, Skagen KR, Krohg-Sorensen K, Holm S, Ritschel V, Holven KB, Biessen EAL, Aukrust P, Dahl TB (2015)
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-210
DOI 10.1016/j.atherosclerosis.2015.09.010

Publications 2014

Abbas A, Aukrust P, Russell D, Krohg-Sorensen K, Almas T, Bundgaard D, Bjerkeli V, Sagen EL, Michelsen AE, Dahl TB, Holm S, Ueland T, Skjelland M, Halvorsen B (2014)
Matrix Metalloproteinase 7 Is Associated with Symptomatic Lesions and Adverse Events in Patients with Carotid Atherosclerosis
PLoS One, 9 (1), e84935
DOI 10.1371/journal.pone.0084935

Halvorsen B, Holm S, Yndestad A, Scholz H, Sagen EL, Nebb H, Holven KB, Dahl TB, Aukrust P (2014)
Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor alpha
Biochem. Biophys. Res. Commun., 450 (4), 1525-1530
DOI 10.1016/j.bbrc.2014.07.036

Halvorsen B, Smedbakken LM, Michelsen AE, Skjelland M, Bjerkeli V, Sagen EL, Tasken K, Bendz B, Gullestad L, Holm S, Biessen EA, Aukrust P (2014)
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13
Atherosclerosis, 234 (2), 352-359
DOI 10.1016/j.atherosclerosis.2014.03.021

Publications 2012

Rodland EK, Ueland T, Bjornsen S, Sagen EL, Dahl CP, Naalsund A, Mollnes TE, Brosstad FR, Muller F, Aukrust P, Froland SS (2012)
Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis
BMC Infect. Dis., 12, 144
DOI 10.1186/1471-2334-12-144

Smedbakken LM, Halvorsen B, Daissormont I, Ranheim T, Michelsen AE, Skjelland M, Sagen EL, Folkersen L, Krohg-Sorensen K, Russell D, Holm S, Ueland T, Fevang B, Hedin U, Yndestad A, Gullestad L, Hansson GK, Biessen EA, Aukrust P (2012)
Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization
Atherosclerosis, 224 (1), 266-273
DOI 10.1016/j.atherosclerosis.2012.06.071

Publications 2008

Handberg A, Skjelland M, Michelsen AE, Sagen EL, Krohg-Sorensen K, Russell D, Dahl A, Ueland T, Oie E, Aukrust P, Halvorsen B (2008)
Soluble CD36 in Plasma Is Increased in Patients With Symptomatic Atherosclerotic Carotid Plaques and Is Related to Plaque Instability
Stroke, 39 (11), 3092-3095
DOI 10.1161/STROKEAHA.108.517128

Publications 2007

Halvorsen B, Sagen EL, Ueland T, Aukrust P, Tonstad S (2007)
Effect of smoking cessation on markers of inflammation and endothelial cell activation among individuals with high risk for cardiovascular disease
Scand. J. Clin. Lab. Invest., 67 (6), 604-611
DOI 10.1080/00365510701283878

Publications 2006

Florholmen G, Halvorsen B, Beraki K, Lyberg T, Sagen EL, Aukrust P, Christensen G, Yndestad A (2006)
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J. Mol. Cell. Cardiol., 41 (4), 689-697
DOI 10.1016/j.yjmcc.2006.07.009