Eva Marie Jacobsen

  • Head of section; Dr. med.
  • +47 23 02 65 12
 

Publications 2024

Eigemann J, Janda A, Schuetz C, Lee-Kirsch MA, Schulz A, Hoenig M, Furlan I, Jacobsen EM, Zinngrebe J, Peters S, Drewes C, Siebert R, Rump EM, Führer M, Lorenz M, Pannicke U, Kölsch U, Debatin KM, von Bernuth H, Schwarz K, Felgentreff K (2024)
Non-Skewed X-inactivation Results in NF-κB Essential Modulator (NEMO) Δ-exon 5-autoinflammatory Syndrome (NEMO-NDAS) in a Female with Incontinentia Pigmenti
J Clin Immunol, 45 (1), 1
DOI 10.1007/s10875-024-01799-2, PubMed 39264518

Fekadu-Siebald J, Fuchs NV, Zahn S, Rommel MGE, Schenk F, Huenecke S, Bremm M, Kreyenberg H, Kuci Z, Jacobsen EM, Hoenig M, Schwarz K, Bader P, Modlich U, König R, Bakhtiar S (2024)
Eight induced pluripotent stem cell lines (iPSCs) derived from two patients with Leukocyte adhesion deficiency Type I (LAD I) with mutations in the ITGB2 gene
Stem Cell Res, 81, 103598
DOI 10.1016/j.scr.2024.103598, PubMed 39522300

Maier FI, Schulz A, Furlan I, Felgentreff K, Jacobsen EM, Sirin M, Schwarz K, Pannicke U, Stursberg J, Debatin KM, Hönig M (2024)
Chemotherapy for a secondary malignancy nearly restores complete chimerism in an SCID-patient after HSCT
Clin Immunol, 259, 109891
DOI 10.1016/j.clim.2024.109891, PubMed 38185266

Stich M, Magalhães VG, Bürger F, Garbade SF, Jeltsch K, Mohr K, Haddad A, Elling R, Lang P, Rabsteyn A, Jacobsen EM, Bode SFN, Müller B, Kräusslich HG, Hoffmann GF, Okun JG, Bartenschlager R, Binder M, Janda A, Renk H, Tönshoff B (2024)
Elevated Soluble ACE2 Activity in Children and Adults After SARS-CoV-2 Exposure Irrespective of Laboratory-Confirmed Infection
J Med Virol, 96 (12), e70098
DOI 10.1002/jmv.70098, PubMed 39624009

Publications 2023

IRF4 International Consortium, Fornes O, Jia A, Kuehn HS, Min Q, Pannicke U, Schleussner N, Thouenon R, Yu Z, de Los Angeles Astbury M, Biggs CM, Galicchio M, Garcia-Campos JA, Gismondi S, Gonzalez Villarreal G, Hildebrand KJ, Hönig M, Hou J, Moshous D, Pittaluga S, Qian X, Rozmus J, Schulz AS, Staines-Boone AT, Sun B et al. (2023)
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency
Sci Immunol, 8 (79), eade7953
DOI 10.1126/sciimmunol.ade7953, PubMed 36662884

Körholz J, Gabrielyan A, Sczakiel HL, Schulze L, Rejzek M, Laass MW, Leuchten N, Tiebel O, Aust D, Conrad K, Röber N, Jacobsen EM, Ehmke N, Berner R, Lucas N, Lee-Kirsch MA, Wiedemuth R, Roesler J, Roers A, Amendt T, Schuetz C (2023)
Novel mutation and expanding phenotype in IRF2BP2 deficiency
Rheumatology (Oxford), 62 (4), 1699-1705
DOI 10.1093/rheumatology/keac575, PubMed 36193988

Larsen TL, Svalastoga M, Brekke J, Enden T, Frøen H, Garresori H, Jacobsen EM, Paulsen PQ, Porojnicu AC, Ree AH, Torfoss D, Velle EO, Wik HS, Ghanima W, Sandset PM, Dahm AEA (2023)
Arterial events in cancer patients treated with apixaban for venous thrombosis
Thromb Res, 228, 128-133
DOI 10.1016/j.thromres.2023.05.017, PubMed 37327527

Lui VG, Hoenig M, Cabrera-Martinez B, Baxter RM, Garcia-Perez JE, Bailey O, Acharya A, Lundquist K, Capera J, Matusewicz P, Hartl FA, D'Abramo M, Alba J, Jacobsen EM, Niewolik D, Lorenz M, Pannicke U, Schulz AS, Debatin KM, Schamel WW, Minguet S, Gumbart JC, Dustin ML, Cambier JC, Schwarz K et al. (2023)
A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation
J Exp Med, 221 (1)
DOI 10.1084/jem.20230927, PubMed 37962568

Magalhães VG, Lukassen S, Drechsler M, Loske J, Burkart SS, Wüst S, Jacobsen EM, Röhmel J, Mall MA, Debatin KM, Eils R, Autenrieth S, Janda A, Lehmann I, Binder M (2023)
Immune-epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
EMBO Rep, 24 (12), e57912
DOI 10.15252/embr.202357912, PubMed 37818799

Mannes M, Pechtl V, Hafner S, Dopler A, Eriksson O, Manivel VA, Wohlgemuth L, Messerer DAC, Schrezenmeier H, Ekdahl KN, Nilsson B, Jacobsen EM, Hoenig M, Huber-Lang M, Braun CK, Schmidt CQ (2023)
Complement and platelets: prothrombotic cell activation requires membrane attack complex-induced release of danger signals
Blood Adv, 7 (20), 6367-6380
DOI 10.1182/bloodadvances.2023010817, PubMed 37428869

Münch AL, Jacobsen EM, Schulz A, Loichinger W, Wowra T, Schiefele L, Elsner J, Westhoff MA, Serra A, Strauss G, Schaarschmidt K, Cario H (2023)
Long-term haematological response and maintained immunological function after laparoscopic subtotal splenectomy in patients with hereditary spherocytosis
Eur J Haematol, 111 (5), 777-786
DOI 10.1111/ejh.14077, PubMed 37700575

Seidel A, Jacobsen EM, Fabricius D, Class M, Zernickel M, Blum C, Conzelmann C, Weil T, Groß R, Bode SFN, Renk H, Elling R, Stich M, Kirchhoff F, Debatin KM, Münch J, Janda A (2023)
Serum neutralizing capacity and T-cell response against the omicron BA.1 variant in seropositive children and their parents one year after SARS-CoV-2 infection
Front Pediatr, 11, 1020865
DOI 10.3389/fped.2023.1020865, PubMed 37051428

Publications 2022

Bode SFN, Haendly M, Fabricius D, Mayer B, Zernickel M, Haddad ADM, Frieh P, Elling R, Renk H, Stich M, Jacobsen EM, Debatin KM, Janda A (2022)
Pulmonary Function and Persistent Clinical Symptoms in Children and Their Parents 12 Months After Mild SARS-CoV-2 Infection
Front Pediatr, 10, 894331
DOI 10.3389/fped.2022.894331, PubMed 35844730

Chen JW, Schickel JN, Tsakiris N, Sng J, Arbogast F, Bouis D, Parisi D, Gera R, Boeckers JM, Delmotte FR, Veselits M, Schuetz C, Jacobsen EM, Posovszky C, Schulz AS, Schwarz K, Clark MR, Menard L, Meffre E (2022)
Positive and negative selection shape the human naive B cell repertoire
J Clin Invest, 132 (2)
DOI 10.1172/JCI150985, PubMed 34813502

de la Morena-Barrio ME, Suchon P, Jacobsen EM, Iversen N, Miñano A, de la Morena-Barrio B, Bravo-Pérez C, Padilla J, Cifuentes R, Asenjo S, Deleuze JF, Trégouët DA, Lozano ML, Vicente V, Sandset PM, Morange PE, Corral J (2022)
Two SERPINC1 variants affecting N-glycosylation of Asn224 cause severe thrombophilia not detected by functional assays
Blood, 140 (2), 140-151
DOI 10.1182/blood.2021014708, PubMed 35486842

Haddad A, Janda A, Renk H, Stich M, Frieh P, Kaier K, Lohrmann F, Nieters A, Willems A, Huzly D, Dulovic A, Schneiderhan-Marra N, Jacobsen EM, Fabricius D, Zernickel M, Stamminger T, Bode SFN, Himpel T, Remppis J, Engel C, Peter A, Ganzenmueller T, Hoffmann GF, Haase B, Kräusslich HG et al. (2022)
Long COVID symptoms in exposed and infected children, adolescents and their parents one year after SARS-CoV-2 infection: A prospective observational cohort study
EBioMedicine, 84, 104245
DOI 10.1016/j.ebiom.2022.104245, PubMed 36155957

Jacobsen EM, Fabricius D, Class M, Topfstedt F, Lorenzetti R, Janowska I, Schmidt F, Staniek J, Zernickel M, Stamminger T, Dietz AN, Zellmer A, Hecht M, Rauch P, Blum C, Ludwig C, Jahrsdörfer B, Schrezenmeier H, Heeg M, Mayer B, Seidel A, Groß R, Münch J, Kirchhoff F, Bode SFN et al. (2022)
High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection
Nat Commun, 13 (1), 7315
DOI 10.1038/s41467-022-35055-1, PubMed 36437276

Janda A, Engel C, Remppis J, Enkel S, Peter A, Hörber S, Ganzenmueller T, Schober S, Weinstock C, Jacobsen EM, Fabricius D, Zernickel M, Stamminger T, Dietz A, Groß HJ, Bode SFN, Haddad ADM, Elling R, Stich M, Tönshoff B, Henneke P, Debatin KM, Franz AR, Renk H (2022)
Role of ABO Blood Group in SARS-CoV-2 Infection in Households
Front Microbiol, 13, 857965
DOI 10.3389/fmicb.2022.857965, PubMed 35602077

Larsen TL, Garresori H, Brekke J, Enden T, Frøen H, Jacobsen EM, Quist-Paulsen P, Porojnicu AC, Ree AH, Torfoss D, Osvik Velle E, Skuterud Wik H, Ghanima W, Sandset PM, Dahm AEA (2022)
Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients - 30 months follow-up
J Thromb Haemost, 20 (5), 1166-1181
DOI 10.1111/jth.15666, PubMed 35114046

Larsen TL, Garresori H, Brekke J, Enden T, Frøen H, Jacobsen EM, Quist-Paulsen P, Porojnicu AC, Ree AH, Torfoss D, Velle EO, Wik HS, Ghanima W, Sandset PM, Dahm AEA (2022)
"Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients - 30 months follow-up": Reply
J Thromb Haemost, 20 (8), 1937-1939
DOI 10.1111/jth.15774, PubMed 35859282

Larsen TL, Ghanima W, Sandset PM, Frøen H, Jacobsen EM, Torfoss D, Dahm AEA (2022)
[Factor Xa inhibitors in the prevention and treatment of venous thromboembolism in cancer patients]
Tidsskr Nor Laegeforen, 142 (1)
DOI 10.4045/tidsskr.22.0228, PubMed 36655971

Pietzsch L, Körholz J, Boschann F, Sergon M, Dorjbal B, Yee D, Gilly V, Kämmerer E, Paul D, Kastl C, Laass MW, Berner R, Jacobsen EM, Roesler J, Aust D, Lee-Kirsch MA, Snow AL, Schuetz C (2022)
Hyper-IgE and Carcinoma in CADINS Disease
Front Immunol, 13, 878989
DOI 10.3389/fimmu.2022.878989, PubMed 35651609

Renk H, Dulovic A, Seidel A, Becker M, Fabricius D, Zernickel M, Junker D, Groß R, Müller J, Hilger A, Bode SFN, Fritsch L, Frieh P, Haddad A, Görne T, Remppis J, Ganzemueller T, Dietz A, Huzly D, Hengel H, Kaier K, Weber S, Jacobsen EM, Kaiser PD, Traenkle B et al. (2022)
Robust and durable serological response following pediatric SARS-CoV-2 infection
Nat Commun, 13 (1), 128
DOI 10.1038/s41467-021-27595-9, PubMed 35013206

Zinngrebe J, Moepps B, Monecke T, Gierschik P, Schlichtig F, Barth TFE, Strauß G, Boldrin E, Posovszky C, Schulz A, Beringer O, Rieser E, Jacobsen EM, Lorenz MR, Schwarz K, Pannicke U, Walczak H, Niessing D, Schuetz C, Fischer-Posovszky P, Debatin KM (2022)
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS
EMBO Mol Med, 14 (3), e14901
DOI 10.15252/emmm.202114901, PubMed 35170849

Publications 2021

Bienias M, Gabrielyan A, Geberzahn L, Rösen-Wolff A, Huebner A, Jacobsen EM, Toepfner N, Fang M, Lee-Kirsch MA, Roesler J, Schuetz C (2021)
More severe than CVID: Combined immunodeficiency due to a novel NFKB2 mutation
Pediatr Allergy Immunol, 32 (4), 793-797
DOI 10.1111/pai.13441, PubMed 33369776

Cocchi N, Jacobsen EM, Hoenig M, Schulz A, Schuetz C (2021)
BCG Disease in SCID: Three Decades of Experience in a Pediatric Transplant Center
J Clin Immunol, 42 (1), 195-198
DOI 10.1007/s10875-021-01143-y, PubMed 34622389

Fabricius D, Ludwig C, Scholz J, Rode I, Tsamadou C, Jacobsen EM, Winkelmann M, Grempels A, Lotfi R, Janda A, Körper S, Adler G, Debatin KM, Schrezenmeier H, Jahrsdörfer B (2021)
mRNA Vaccines Enhance Neutralizing Immunity against SARS-CoV-2 Variants in Convalescent and ChAdOx1-Primed Subjects
Vaccines (Basel), 9 (8)
DOI 10.3390/vaccines9080918, PubMed 34452043

Felgentreff K, Baumann U, Klemann C, Schuetz C, Viemann D, Wetzke M, Pannicke U, von Hardenberg S, Auber B, Debatin KM, Jacobsen EM, Hoenig M, Schulz A, Schwarz K (2021)
Biomarkers of DNA Damage Response Enable Flow Cytometry-Based Diagnostic to Identify Inborn DNA Repair Defects in Primary Immunodeficiencies
J Clin Immunol, 42 (2), 286-298
DOI 10.1007/s10875-021-01156-7, PubMed 34716846

Felgentreff K, Schuetz C, Baumann U, Klemann C, Viemann D, Ursu S, Jacobsen EM, Debatin KM, Schulz A, Hoenig M, Schwarz K (2021)
Differential DNA Damage Response of Peripheral Blood Lymphocyte Populations
Front Immunol, 12, 739675
DOI 10.3389/fimmu.2021.739675, PubMed 34594342

Fiskvik H, Jacobsen AF, Iversen N, Henriksson CE, Jacobsen EM (2021)
Treatment of Homozygous Type II Antithrombin Heparin-Binding Site Deficiency in Pregnancy
Case Rep Obstet Gynecol, 2021, 4393821
DOI 10.1155/2021/4393821, PubMed 34513101

Körholz J, Gabrielyan A, Sowerby JM, Boschann F, Chen LS, Paul D, Brandt D, Kleymann J, Kolditz M, Toepfner N, Knöfler R, Jacobsen EM, Wolf C, Conrad K, Röber N, Lee-Kirsch MA, Smith KGC, Mundlos S, Berner R, Dalpke AH, Schuetz C, Rae W (2021)
One Gene, Many Facets: Multiple Immune Pathway Dysregulation in SOCS1 Haploinsufficiency
Front Immunol, 12, 680334
DOI 10.3389/fimmu.2021.680334, PubMed 34421895

Publications 2020

Hannevik TL, Brekke J, Enden T, Frøen H, Garresori H, Jacobsen EM, Paulsen PQ, Porojnicu AC, Ree AH, Torfoss D, Velle EO, Wik HS, Ghanima W, Sandset PM, Dahm AEA (2020)
Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism
Thromb Res, 196, 238-244
DOI 10.1016/j.thromres.2020.08.042, PubMed 32919178

Hoenig M, Roesler J, Seidel MG, Albert MH, Hauck F, Maecker-Kolhoff B, Eiz-Vesper B, Kleinschmidt K, Debatin KM, Jacobsen EM, Furlan I, Suttorp M, Schuetz C, Schulz AS (2020)
Matched Family Donor Lymphocyte Infusions as First Cellular Therapy for Patients with Severe Primary T Cell Deficiencies
Transplant Cell Ther, 27 (1), 93.e1-93.e8
DOI 10.1016/j.bbmt.2020.09.037, PubMed 33022377

Wildermann C, Alosaimi M, Liebenehm S, Jacobsen EM, Barth TFE, Möller P, Debatin KM, Schulz A, Sirin M, Abosoudah IF, Alkuraya FS, Geha RS, Hönig M (2020)
Successful hematopoietic stem cell transplantation in a 4-1BB deficient patient with EBV-induced lymphoproliferation
Clin Immunol, 222, 108639
DOI 10.1016/j.clim.2020.108639, PubMed 33259966

Publications 2019

Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM (2019)
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974

Kristoffersen AH, Jacobsen EM, Varsi K, Henriksson CE (2019)
[Analysis of lupus anticoagulant during ongoing anticoagulation therapy]
Tidsskr Nor Laegeforen, 139 (15)
DOI 10.4045/tidsskr.19.0096, PubMed 31642626

Kristoffersen AH, Jacobsen EM, Varsi K, Henriksson CE (2019)
Analysis of lupus anticoagulant during ongoing anti coagulation treatment
Tidsskr. Nor. Laegeforen., 139 (15), 1491

Salomé B, Gomez-Cadena A, Loyon R, Suffiotti M, Salvestrini V, Wyss T, Vanoni G, Ruan DF, Rossi M, Tozzo A, Tentorio P, Bruni E, Riether C, Jacobsen EM, Jandus P, Conrad C, Hoenig M, Schulz A, Michaud K, Della Porta MG, Salvatore S, Ho PC, Gfeller D, Ochsenbein A, Mavilio D et al. (2019)
CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML
Blood Adv, 3 (22), 3674-3687
DOI 10.1182/bloodadvances.2018030478, PubMed 31765481

Schultz NH, Holme PA, Henriksson CE, Mowinckel MC, Sandset PM, Bratseth V, Jacobsen EM (2019)
The influence of rivaroxaban on markers of fibrinolysis and endothelial cell activation/injury in patients with venous thrombosis
Thromb Res, 177, 154-156
DOI 10.1016/j.thromres.2019.03.010, PubMed 30903875

Volpi S, Cicalese MP, Tuijnenburg P, Tool ATJ, Cuadrado E, Abu-Halaweh M, Ahanchian H, Alzyoud R, Akdemir ZC, Barzaghi F, Blank A, Boisson B, Bottino C, Brigida I, Caorsi R, Casanova JL, Chiesa S, Chinn IK, Dückers G, Enders A, Erichsen HC, Forbes LR, Gambin T, Gattorno M, Karimiani EG et al. (2019)
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency
J Allergy Clin Immunol, 143 (6), 2296-2299
DOI 10.1016/j.jaci.2019.02.003, PubMed 30771411

Wu Z, Subramanian N, Jacobsen EM, Laib Sampaio K, van der Merwe J, Hönig M, Mertens T (2019)
NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV
Microorganisms, 7 (11)
DOI 10.3390/microorganisms7110546, PubMed 31717670

Publications 2018

Ege MJ, Schuetz C, Jacobsen EM, Müller-Langer SM, Furlan I, Sirin M, Pannicke U, Schwarz K, Debatin KM, Hönig M, Schulz A, Friedrich W (2018)
Late thymic deficiency after HLA-haploidentical hematopoietic stem cell transplantation for severe combined immunodeficiency
J Allergy Clin Immunol, 143 (4), 1623-1626.e13
DOI 10.1016/j.jaci.2018.11.027, PubMed 30529243

Gravensteen IK, Jacobsen EM, Sandset PM, Helgadottir LB, Rådestad I, Sandvik L, Ekeberg Ø (2018)
Anxiety, depression and relationship satisfaction in the pregnancy following stillbirth and after the birth of a live-born baby: a prospective study
BMC Pregnancy Childbirth, 18 (1), 41
DOI 10.1186/s12884-018-1666-8, PubMed 29361916

Panagopoulos I, Gorunova L, Jacobsen EM, Andersen K, Micci F, Heim S (2018)
RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia
PLoS One, 13 (4), e0196181
DOI 10.1371/journal.pone.0196181, PubMed 29672642

Schleker T, Jacobsen EM, Mayer B, Strauss G, Debatin KM, Posovszky C (2018)
Preserved in vitro immunoreactivity in children receiving long-term immunosuppressive therapy due to inflammatory bowel disease or autoimmune hepatitis
Mol Cell Pediatr, 5 (1), 1
DOI 10.1186/s40348-018-0079-0, PubMed 29352427

Schultz NH, Holme PA, Bjørnsen S, Henriksson CE, Sandset PM, Jacobsen EM (2018)
The impact of rivaroxaban on primary hemostasis in patients with venous thrombosis
Platelets, 31 (1), 43-47
DOI 10.1080/09537104.2018.1557618, PubMed 30569801

Publications 2017

Gravensteen IK, Jacobsen EM, Sandset PM, Helgadottir LB, Rådestad I, Sandvik L, Ekeberg Ø (2017)
Healthcare utilisation, induced labour and caesarean section in the pregnancy after stillbirth: a prospective study
BJOG, 125 (2), 202-210
DOI 10.1111/1471-0528.14750, PubMed 28516500

Hoenig M, Lagresle-Peyrou C, Pannicke U, Notarangelo LD, Porta F, Gennery AR, Slatter M, Cowan MJ, Stepensky P, Al-Mousa H, Al-Zahrani D, Pai SY, Al Herz W, Gaspar HB, Veys P, Oshima K, Imai K, Yabe H, Noroski LM, Wulffraat NM, Sykora KW, Soler-Palacin P, Muramatsu H, Al Hilali M, Moshous D et al. (2017)
Reticular dysgenesis: international survey on clinical presentation, transplantation, and outcome
Blood, 129 (21), 2928-2938
DOI 10.1182/blood-2016-11-745638, PubMed 28331055

Publications 2016

Garabet L, Gilboe IM, Mowinckel MC, Jacobsen AF, Mollnes TE, Sandset PM, Jacobsen EM (2016)
Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus
Scand J Immunol, 84 (2), 95-9
DOI 10.1111/sji.12445, PubMed 27135178

Publications 2015

Berntsen CF, Kristiansen A, Akl EA, Sandset PM, Jacobsen EM, Guyatt G, Vandvik PO (2015)
Compression Stockings for Preventing the Postthrombotic Syndrome in Patients with Deep Vein Thrombosis
Am J Med, 129 (4), 447.e1-447.e20
DOI 10.1016/j.amjmed.2015.11.031, PubMed 26747198

Publications 2014

Jacobsen EM, Dahm AE, Vartdal T, Sandset PM (2014)
[Anticoagulation for venous thrombosis and internal diseases]
Tidsskr Nor Laegeforen, 134 (9), 924
DOI 10.4045/tidsskr.13.1597, PubMed 24828715

Kristiansen A, Brandt L, Agoritsas T, Akl EA, Berge E, Bondi J, Dahm AE, Granan LP, Halvorsen S, Holme PA, Flem Jacobsen A, Jacobsen EM, Neumann I, Sandset PM, Sætre T, Tveit A, Vartdal T, Guyatt G, Vandvik PO (2014)
Adaptation of trustworthy guidelines developed using the GRADE methodology: a novel five-step process
Chest, 146 (3), 727-734
DOI 10.1378/chest.13-2828, PubMed 25180723

Publications 2013

Gravensteen IK, Helgadóttir LB, Jacobsen EM, Rådestad I, Sandset PM, Ekeberg O (2013)
Women's experiences in relation to stillbirth and risk factors for long-term post-traumatic stress symptoms: a retrospective study
BMJ Open, 3 (10), e003323
DOI 10.1136/bmjopen-2013-003323, PubMed 24154514

Helgadóttir LB, Turowski G, Skjeldestad FE, Jacobsen AF, Sandset PM, Roald B, Jacobsen EM (2013)
Classification of stillbirths and risk factors by cause of death--a case-control study
Acta Obstet Gynecol Scand, 92 (3), 325-33
DOI 10.1111/aogs.12044, PubMed 23157574

Schuetz C, Pannicke U, Jacobsen EM, Burggraf S, Albert MH, Hönig M, Niehues T, Feyen O, Ehl S, Debatin KM, Friedrich W, Schulz AS, Schwarz K (2013)
Lesson from hypomorphic recombination-activating gene (RAG) mutations: Why asymptomatic siblings should also be tested
J Allergy Clin Immunol, 133 (4), 1211-5
DOI 10.1016/j.jaci.2013.10.021, PubMed 24331380

Publications 2012

Dahm AE, Bezemer ID, Bergrem A, Jacobsen AF, Jacobsen EM, Skretting G, Rosendaal FR, Sandset PM (2012)
Candidate gene polymorphisms and the risk for pregnancy-related venous thrombosis
Br J Haematol, 157 (6), 753-61
DOI 10.1111/j.1365-2141.2012.09121.x, PubMed 22533697

Gravensteen IK, Helgadottir LB, Jacobsen EM, Sandset PM, Ekeberg Ø (2012)
Long-term impact of intrauterine fetal death on quality of life and depression: a case-control study
BMC Pregnancy Childbirth, 12, 43
DOI 10.1186/1471-2393-12-43, PubMed 22676992

Turowski G, Berge LN, Helgadottir LB, Jacobsen EM, Roald B (2012)
A new, clinically oriented, unifying and simple placental classification system
Placenta, 33 (12), 1026-35
DOI 10.1016/j.placenta.2012.10.002, PubMed 23110739

Publications 2011

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
Incidence and risk factors of fetal death in Norway: a case-control study
Acta Obstet Gynecol Scand, 90 (4), 390-7
DOI 10.1111/j.1600-0412.2011.01079.x, PubMed 21306337

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
The association of antiphospholipid antibodies with intrauterine fetal death: a case-control study
Thromb Res, 130 (1), 32-7
DOI 10.1016/j.thromres.2011.11.029, PubMed 22178574

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
The association of inherited thrombophilia and intrauterine fetal death: a case-control study
Blood Coagul Fibrinolysis, 22 (8), 651-6
DOI 10.1097/MBC.0b013e32834a614c, PubMed 22198364

Publications 2010

Berentsen S, Randen U, Vågan AM, Hjorth-Hansen H, Vik A, Dalgaard J, Jacobsen EM, Thoresen AS, Beiske K, Tjønnfjord GE (2010)
High response rate and durable remissions following fludarabine and rituximab combination therapy for chronic cold agglutinin disease
Blood, 116 (17), 3180-4
DOI 10.1182/blood-2010-06-288647, PubMed 20634373

Bergrem A, Jacobsen EM, Skjeldestad FE, Jacobsen AF, Skogstad M, Sandset PM (2010)
The association of antiphospholipid antibodies with pregnancy-related first time venous thrombosis--a population-based case-control study
Thromb Res, 125 (5), e222-7
DOI 10.1016/j.thromres.2009.12.006, PubMed 20051285

Bjornaas MA, Jacobsen EM, Jacobsen D (2010)
Nonfatal self-poisoning with LMW heparin and the use of antidote
Thromb Res, 126 (5), e403-5
DOI 10.1016/j.thromres.2010.08.026, PubMed 20870279

Jacobsen AF, Dahm A, Bergrem A, Jacobsen EM, Sandset PM (2010)
Risk of venous thrombosis in pregnancy among carriers of the factor V Leiden and the prothrombin gene G20210A polymorphisms
J Thromb Haemost, 8 (11), 2443-9
DOI 10.1111/j.1538-7836.2010.04038.x, PubMed 20735725

Publications 2008

Haga HJ, Jacobsen EM, Peen E (2008)
Incidence of thromboembolic events in patients with primary Sjögren's syndrome
Scand J Rheumatol, 37 (2), 127-9
DOI 10.1080/03009740701716843, PubMed 18415770

Publications 2007

Galli M, Borrelli G, Jacobsen EM, Marfisi RM, Finazzi G, Marchioli R, Wisloff F, Marziali S, Morboeuf O, Barbui T (2007)
Clinical significance of different antiphospholipid antibodies in the WAPS (warfarin in the antiphospholipid syndrome) study
Blood, 110 (4), 1178-83
DOI 10.1182/blood-2007-01-066043, PubMed 17440049

Publications 2006

Jacobsen EM, Trettenes EJ, Wisløff F, Abildgaard U (2006)
Detection and quantification of lupus anticoagulants in plasma from heparin treated patients, using addition of polybrene
Thromb J, 4, 3
DOI 10.1186/1477-9560-4-3, PubMed 16436199

Liestøl S, Sandset PM, Jacobsen EM, Mowinckel MC, Wisløff F (2006)
Decreased anticoagulant response to tissue factor pathway inhibitor type 1 in plasmas from patients with lupus anticoagulants
Br J Haematol, 136 (1), 131-7
DOI 10.1111/j.1365-2141.2006.06385.x, PubMed 17092306

Strauss G, Osen W, Knape I, Jacobsen EM, Müller SM, Debatin KM (2006)
Membrane-bound CD95 ligand expressed on human antigen-presenting cells prevents alloantigen-specific T cell response without impairment of viral and third-party T cell immunity
Cell Death Differ, 14 (3), 480-8
DOI 10.1038/sj.cdd.4402019, PubMed 16902496

Publications 2002

Liestøl S, Jacobsen EM, Wisløff F (2002)
Dilute prothrombin time-based lupus ratio test. Integrated LA testing with recombinant tissue thromboplastin
Thromb Res, 105 (2), 177-82
DOI 10.1016/s0049-3848(01)00420-0, PubMed 11958810

Wisløff F, Jacobsen EM, Liestøl S (2002)
Laboratory diagnosis of the antiphospholipid syndrome
Thromb Res, 108 (5-6), 263-71
DOI 10.1016/s0049-3848(02)00400-0, PubMed 12676184

Publications 2001

Jacobsen EM (2001)
Laboratory evaluation of lupus anticoagulants and their interference with coagulation inhibitors
Haematological Research Laboratory, Ullevål University Hospital, Oslo, 1 b. (flere pag.)
BIBSYS 012115037, ISBN 82-91675-16-3

Jacobsen EM, Barna-Cler L, Taylor JM, Triplett DA, Wisløff F (2001)
The evaluation of clotting times in the laboratory detection of lupus anticoagulants
Thromb Res, 104 (4), 275-82
DOI 10.1016/s0049-3848(01)00365-6, PubMed 11728529

Publications 2000

Jacobsen EM, Barna-Cler L, Taylor JM, Triplett DA, Wisløff F (2000)
The Lupus Ratio test--an interlaboratory study on the detection of Lupus anticoagulants by an APTT-based, integrated, and semi-quantitative test. Fifth International Survey of Lupus Anticoagulants--ISLA 5
Thromb Haemost, 83 (5), 704-8
PubMed 10823266

Publications 1999

Jacobsen EM, Sandset PM, Wisløff F (1999)
Do antiphospholipid antibodies interfere with tissue factor pathway inhibitor?
Thromb Res, 94 (4), 213-20
DOI 10.1016/s0049-3848(98)00195-9, PubMed 10336236

Kalff-Suske M, Wild A, Topp J, Wessling M, Jacobsen EM, Bornholdt D, Engel H, Heuer H, Aalfs CM, Ausems MG, Barone R, Herzog A, Heutink P, Homfray T, Gillessen-Kaesbach G, König R, Kunze J, Meinecke P, Müller D, Rizzo R, Strenge S, Superti-Furga A, Grzeschik KH (1999)
Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome
Hum Mol Genet, 8 (9), 1769-77
DOI 10.1093/hmg/8.9.1769, PubMed 10441342

Publications 1997

Jacobsen EM, Wisløff F (1997)
A simple procedure that increases the specificity of the activated protein C resistance test in samples containing antiphospholipid antibodies
Thromb Res, 86 (5), 385-91
DOI 10.1016/s0049-3848(97)00083-2, PubMed 9211629

Publications 1996

Jacobsen EM, Sandset PM, Wisløff F (1996)
Lupus anticoagulant and a functional assay for tissue factor pathway inhibitor
Thromb Res, 83 (4), 339-40
DOI 10.1016/0049-3848(96)00142-9, PubMed 8870178

Jacobsen EM, Wisløff F (1996)
False negative screening tests for lupus anticoagulants--an unrecognized problem?
Thromb Res, 82 (5), 445-51
DOI 10.1016/0049-3848(96)00094-1, PubMed 8771705

Publications 1995

Jacobsen EM, Wisløff F, Finset A (1995)
[Does social support have an impact on the prognosis in cancer?]
Tidsskr Nor Laegeforen, 115 (24), 3022-5
PubMed 7570530