Beata Grallert
- Scientist, project leader
- +47 22 78 19 80
Publications 2023
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955
Publications 2022
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630
Publications 2021
Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465
Publications 2019
Cell-Cycle-Dependent Regulation of Translation: New Interpretations of Old Observations in Light of New Approaches
Bioessays, 41 (8), e1900022
DOI 10.1002/bies.201900022, PubMed 31210378
eIF2α phosphorylation and the regulation of translation
Curr Genet, 66 (2), 293-297
DOI 10.1007/s00294-019-01026-1, PubMed 31485739
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res, 47 (4), 1797-1813
DOI 10.1093/nar/gky1233, PubMed 30541148
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Nanotoxicology, 13 (6), 761-782
DOI 10.1080/17435390.2019.1576238, PubMed 30760074
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194
Publications 2018
A novel role for ATR/Rad3 in G1 phase
Sci Rep, 8 (1), 6880
DOI 10.1038/s41598-018-25238-6, PubMed 29720710
Regulation of global translation during the cell cycle
J Cell Sci, 131 (17)
DOI 10.1242/jcs.220327, PubMed 30072440
Mitotic defects in fission yeast lipid metabolism 'cut' mutants are suppressed by ammonium chloride
FEMS Yeast Res, 18 (6)
DOI 10.1093/femsyr/foy064, PubMed 29931271
Publications 2017
Activation of Gcn2 in response to different stresses
PLoS One, 12 (8), e0182143
DOI 10.1371/journal.pone.0182143, PubMed 28771613
A checkpoint-independent mechanism delays entry into mitosis after UV irradiation
J Cell Sci, 130 (23), 4028-4037
DOI 10.1242/jcs.204693, PubMed 29046339
Publications 2016
Consequences of abnormal CDK activity in S phase
Cell Cycle, 15 (7), 963-73
DOI 10.1080/15384101.2016.1152423, PubMed 26918805
Analyzing Schizosaccharomyces pombe DNA Content by Flow Cytometry
Cold Spring Harb Protoc, 2016 (6)
DOI 10.1101/pdb.prot091280, PubMed 27250946
Publications 2015
Simultaneous measurement of passage through the restriction point and MCM loading in single cells
Nucleic Acids Res, 43 (22), e150
DOI 10.1093/nar/gkv744, PubMed 26250117
Stress-induced inhibition of translation independently of eIF2α phosphorylation
J Cell Sci, 128 (23), 4420-7
DOI 10.1242/jcs.176545, PubMed 26493332
Publications 2014
Cell-cycle analyses using thymidine analogues in fission yeast
PLoS One, 9 (2), e88629
DOI 10.1371/journal.pone.0088629, PubMed 24551125
Publications 2013
GCN2, an old dog with new tricks
Biochem Soc Trans, 41 (6), 1687-91
DOI 10.1042/BST20130210, PubMed 24256275
Crosstalk between the Tor and Gcn2 pathways in response to different stresses
Cell Cycle, 13 (3), 453-61
DOI 10.4161/cc.27270, PubMed 24280780
Publications 2012
Hpz1 modulates the G1-S transition in fission yeast
PLoS One, 7 (9), e44539
DOI 10.1371/journal.pone.0044539, PubMed 22970243
Induction of a G1-S checkpoint in fission yeast
Proc Natl Acad Sci U S A, 109 (25), 9911-6
DOI 10.1073/pnas.1204901109, PubMed 22665798
Publications 2011
Cell-cycle analysis of fission yeast cells by flow cytometry
PLoS One, 6 (2), e17175
DOI 10.1371/journal.pone.0017175, PubMed 21386895
Publications 2009
In DNA replication, the early bird catches the worm
Cell, 136 (5), 812-4
DOI 10.1016/j.cell.2009.02.023, PubMed 19269359
Checkpoint regulation of DNA replication
Methods Mol Biol, 521, 55-70
DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101
Global transcriptional response after exposure of fission yeast cells to ultraviolet light
BMC Cell Biol, 10, 87
DOI 10.1186/1471-2121-10-87, PubMed 20015352
Publications 2008
Rapid regulation of protein activity in fission yeast
BMC Cell Biol, 9, 23
DOI 10.1186/1471-2121-9-23, PubMed 18457584
The multiple facets of the intra-S checkpoint
Cell Cycle, 7 (15), 2315-20
DOI 10.4161/cc.6389, PubMed 18677104
The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
J Cell Sci, 121 (Pt 24), 4047-54
DOI 10.1242/jcs.035428, PubMed 19033384
Publications 2007
The Gcn2 kinase as a cell cycle regulator
Cell Cycle, 6 (22), 2768-72
DOI 10.4161/cc.6.22.4933, PubMed 17986863
A novel checkpoint mechanism regulating the G1/S transition
Genes Dev, 21 (6), 649-54
DOI 10.1101/gad.421807, PubMed 17369398
Publications 2004
Germinating fission yeast spores delay in G1 in response to UV irradiation
BMC Cell Biol, 5 (1), 40
DOI 10.1186/1471-2121-5-40, PubMed 15498101
Publications 2003
Intra-G1 arrest in response to UV irradiation in fission yeast
Proc Natl Acad Sci U S A, 100 (19), 10758-63
DOI 10.1073/pnas.1833769100, PubMed 12960401
Publications 2002
A novel chk1-dependent G1/M checkpoint in fission yeast
J Cell Sci, 115 (Pt 18), 3609-18
DOI 10.1242/jcs.00004, PubMed 12186947
Publications 2001
[The 2001 Nobel Prize in Physiology or Medicine]
Tidsskr Nor Laegeforen, 121 (30), 3500
PubMed 11808003
Publications 2000
A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
J Cell Sci, 113 ( Pt 8), 1447-58
DOI 10.1242/jcs.113.8.1447, PubMed 10725227
Publications 1999
Regulation of the start of DNA replication in Schizosaccharomyces pombe
J Cell Sci, 112 ( Pt 6), 939-46
DOI 10.1242/jcs.112.6.939, PubMed 10036243
Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation
Yeast, 15 (8), 669-86
DOI 10.1002/(SICI)1097-0061(19990615)15:8<669::AID-YEA411>3.0.CO;2-K, PubMed 10392445
Publications 1998
Coordination of initiation of nuclear division and initiation of cell division in Schizosaccharomyces pombe: genetic interactions of mutations
J Bacteriol, 180 (4), 892-900
DOI 10.1128/JB.180.4.892-900.1998, PubMed 9473044
Publications 1997
Measurement of nuclear DNA content in fission yeast by flow cytometry
Yeast, 13 (14), 1329-35
DOI 10.1002/(SICI)1097-0061(199711)13:14<1329::AID-YEA185>3.0.CO;2-M, PubMed 9392077
An approach to identify functional homologues and suppressors of genes in fission yeast
Curr Genet, 32 (1), 27-31
DOI 10.1007/s002940050244, PubMed 9309167
Publications 1996
The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase
Genes Dev, 10 (20), 2644-54
DOI 10.1101/gad.10.20.2644, PubMed 8895665
Publications 1995
DNA polymerase alpha, a component of the replication initiation complex, is essential for the checkpoint coupling S phase to mitosis in fission yeast
J Cell Sci, 108 ( Pt 9), 3109-18
DOI 10.1242/jcs.108.9.3109, PubMed 8537450
Publications 1993
A study of integrative transformation in Schizosaccharomyces pombe
Mol Gen Genet, 238 (1-2), 26-32
DOI 10.1007/BF00279526, PubMed 8479431
Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations
J Cell Sci, 104 ( Pt 2), 485-93
DOI 10.1242/jcs.104.2.485, PubMed 8505375
Publications 1991
Common genes and pathways in the regulation of the mitotic and meiotic cell cycles of Schizosaccharomyces pombe
Curr Genet, 20 (3), 199-204
DOI 10.1007/BF00326233, PubMed 1934126
Publications 1990
Dissociation of meiotic and mitotic roles of the fission yeast cdc2 gene
Mol Gen Genet, 222 (2-3), 473-5
DOI 10.1007/BF00633860, PubMed 2274045