Pål Gunnar Larsson
- Head of section; MD, PhD
- +47 23 07 44 07
Publications 2024
Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods
J Neurosci Methods, 404, 110056
DOI 10.1016/j.jneumeth.2024.110056, PubMed 38224783
Norwegian population-based study of effectiveness of vagus nerve stimulation in patients with developmental and epileptic encephalopathies
Epilepsia Open, 9 (2), 704-716
DOI 10.1002/epi4.12908, PubMed 38318727
Multiple intrinsic timescales govern distinct brain states in human sleep
J Neurosci (in press)
DOI 10.1523/JNEUROSCI.0171-24.2024, PubMed 39187378
Ramping dynamics and theta oscillations reflect dissociable signatures during rule-guided human behavior
Nat Commun, 15 (1), 637
DOI 10.1038/s41467-023-44571-7, PubMed 38245516
Publications 2023
Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods
bioRxiv
DOI 10.1101/2023.05.08.539503, PubMed 37214984
Decision and response monitoring during working memory are sequentially represented in the human insula
iScience, 26 (10), 107653
DOI 10.1016/j.isci.2023.107653, PubMed 37674986
Combining MRI and Spectral EEG for Assessment of Neurocognitive Outcomes in Preterm Infants
Neonatology, 120 (4), 482-490
DOI 10.1159/000530648, PubMed 37290419
Inter-site generalizability of EEG based age prediction algorithms in the preterm infant
Physiol Meas, 44 (7)
DOI 10.1088/1361-6579/ace755, PubMed 37442141
Subspace partitioning in the human prefrontal cortex resolves cognitive interference
Proc Natl Acad Sci U S A, 120 (28), e2220523120
DOI 10.1073/pnas.2220523120, PubMed 37399398
Whole-exome sequencing in moyamoya patients of Northern-European origin identifies gene variants involved in Nitric Oxide metabolism: A pilot study
Brain Spine, 3, 101745
DOI 10.1016/j.bas.2023.101745, PubMed 37383439
Publications 2022
Episodic Memory Dysfunction and Effective Connectivity in Adult Patients With Newly Diagnosed Nonlesional Temporal Lobe Epilepsy
Front Neurol, 13, 774532
DOI 10.3389/fneur.2022.774532, PubMed 35222242
Modeling intracranial electrodes. A simulation platform for the evaluation of localization algorithms
Front Neuroinform, 16, 788685
DOI 10.3389/fninf.2022.788685, PubMed 36277477
Orbitofrontal cortex governs working memory for temporal order
Curr Biol, 32 (9), R410-R411
DOI 10.1016/j.cub.2022.03.074, PubMed 35537388
Early spectral EEG in preterm infants correlates with neurocognitive outcomes in late childhood
Pediatr Res, 92 (4), 1132-1139
DOI 10.1038/s41390-021-01915-7, PubMed 35013563
Monitoring the Awake and Anesthetized Unconscious States Using Bispectral Index and Electroencephalographic Connectivity Measures
Clin EEG Neurosci, 54 (3), 273-280
DOI 10.1177/15500594221131680, PubMed 36226378
Publications 2021
Cognition in adult patients with newly diagnosed non-lesional temporal lobe epilepsy
Epilepsy Behav, 116, 107771
DOI 10.1016/j.yebeh.2021.107771, PubMed 33545650
Top-Down Attentional Modulation in Human Frontal Cortex: Differential Engagement during External and Internal Attention
Cereb Cortex, 31 (2), 873-883
DOI 10.1093/cercor/bhaa262, PubMed 33063100
Norwegian population-based study of long-term effects, safety, and predictors of response of vagus nerve stimulation treatment in drug-resistant epilepsy: The NORPulse study
Epilepsia, 63 (2), 414-425
DOI 10.1111/epi.17152, PubMed 34935136
Intracranial Recordings Demonstrate Both Cortical and Medial Temporal Lobe Engagement in Visual Search in Humans
J Cogn Neurosci, 33 (9), 1833-1861
DOI 10.1162/jocn_a_01739, PubMed 34375422
Publications 2020
Validation of a new approach for distinguishing anesthetized from awake state in patients using directed transfer function applied to raw EEG
J Clin Monit Comput, 35 (6), 1381-1394
DOI 10.1007/s10877-020-00603-x, PubMed 33064257
Criteria for defining interictal epileptiform discharges in EEG: A clinical validation study
Neurology, 94 (20), e2139-e2147
DOI 10.1212/WNL.0000000000009439, PubMed 32321764
Optimized set of criteria for defining interictal epileptiform EEG discharges
Clin Neurophysiol, 131 (9), 2250-2254
DOI 10.1016/j.clinph.2020.06.026, PubMed 32731161
An electrophysiological marker of arousal level in humans
Elife, 9
DOI 10.7554/eLife.55092, PubMed 32720644
Publications 2019
Safety aspects of antiepileptic drugs-a population-based study of adverse effects relative to changes in utilisation
Eur J Clin Pharmacol, 75 (8), 1153-1160
DOI 10.1007/s00228-019-02678-1, PubMed 31001654
Auditory deviance detection in the human insula: An intracranial EEG study
Cortex, 121, 189-200
DOI 10.1016/j.cortex.2019.09.002, PubMed 31629197
Quantitative EEG analysis in Encephalopathy related to Status Epilepticus during slow Sleep
Epileptic Disord, 21 (S1), 31-40
DOI 10.1684/epd.2019.1055, PubMed 31149902
EEG features in Encephalopathy related to Status Epilepticus during slow Sleep
Epileptic Disord, 21 (S1), 22-30
DOI 10.1684/epd.2019.1054, PubMed 31162114
Corrigendum to "Seizure-like episodes and EEG abnormalities in patients with long QT syndrome" [Seizure 61 (2018) 214-220]
Seizure, 69, 304
DOI 10.1016/j.seizure.2018.12.002, PubMed 31056410
Default network and frontoparietal control network theta connectivity supports internal attention
Nat Hum Behav, 3 (12), 1263-1270
DOI 10.1038/s41562-019-0717-0, PubMed 31477910
Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: A systematic review from the E-PILEPSY consortium
Clin Neurophysiol, 130 (5), 845-855
DOI 10.1016/j.clinph.2018.12.016, PubMed 30824202
Publications 2018
Complications related to induced abortion: a combined retrospective and longitudinal follow-up study
BMC Womens Health, 18 (1), 158
DOI 10.1186/s12905-018-0645-6, PubMed 30253769
Seizure-like episodes and EEG abnormalities in patients with long QT syndrome
Seizure, 61, 214-220
DOI 10.1016/j.seizure.2018.08.020, PubMed 30218808
Dynamic frontotemporal systems process space and time in working memory
PLoS Biol, 16 (3), e2004274
DOI 10.1371/journal.pbio.2004274, PubMed 29601574
Distinguishing Anesthetized from Awake State in Patients: A New Approach Using One Second Segments of Raw EEG
Front Hum Neurosci, 12, 40
DOI 10.3389/fnhum.2018.00040, PubMed 29515381
Publications 2017
Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015
Epilepsy Res, 139, 35-42
DOI 10.1016/j.eplepsyres.2017.11.001, PubMed 29175562
Erratum to: Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-A pharmacoepidemiological study and clinical implications
Eur J Clin Pharmacol, 73 (6), 791-792
DOI 10.1007/s00228-017-2252-0, PubMed 28389679
Seizure outcomes of temporal lobe epilepsy surgery in patients with normal MRI and without specific histopathology
Acta Neurochir (Wien), 159 (5), 757-766
DOI 10.1007/s00701-017-3127-y, PubMed 28281007
Publications 2016
Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-a pharmacoepidemiological study and clinical implications
Eur J Clin Pharmacol, 72 (10), 1245-1254
DOI 10.1007/s00228-016-2092-3, PubMed 27411937
Ictal EEG source imaging in presurgical evaluation: High agreement between analysis methods
Seizure, 43, 1-5
DOI 10.1016/j.seizure.2016.09.017, PubMed 27764709
Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe
Epilepsia, 57 (5), 770-6
DOI 10.1111/epi.13347, PubMed 27012361
Publications 2015
Effective connectivity in long-term EEG monitoring in preterm infants
Clin Neurophysiol, 126 (12), 2261-8
DOI 10.1016/j.clinph.2015.01.017, PubMed 25735477
Seizure outcomes in relation to the extent of resection of the perifocal fluorodeoxyglucose and flumazenil PET abnormalities in anteromedial temporal lobectomy
Acta Neurochir (Wien), 157 (11), 1905-16
DOI 10.1007/s00701-015-2578-2, PubMed 26350516
Publications 2014
The effect of blood glucose and pCO2 on spectral EEG of premature infants during the first three days of life
Neonatology, 105 (4), 297-305
DOI 10.1159/000357291, PubMed 24643078
Publications 2013
Subclinical epileptiform activity in children with electrical status epilepticus during sleep: effects on cognition and behavior before and after treatment with levetiracetam
Epilepsy Behav, 27 (1), 40-8
DOI 10.1016/j.yebeh.2012.12.007, PubMed 23376335
The way out of Babel
Epilepsia, 54 (4), 767-8
DOI 10.1111/epi.12110, PubMed 23550936
Pharmacological treatment of psychiatric comorbidity in patients with refractory epilepsy
Epilepsy Behav, 29 (1), 77-81
DOI 10.1016/j.yebeh.2013.06.031, PubMed 23939032
[Reply on TWAR: Lies, damned lies and registry data]
Lakartidningen, 110 (48), 2183
PubMed 24432502
Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice
Diabetologia, 56 (4), 867-74
DOI 10.1007/s00125-013-2834-z, PubMed 23344730
Automated spectral EEG analyses of premature infants during the first three days of life correlated with developmental outcomes at 24 months
Neonatology, 103 (3), 205-12
DOI 10.1159/000345923, PubMed 23327994
Publications 2012
Application of a computational model of vagus nerve stimulation
Acta Neurol Scand, 126 (5), 336-43
DOI 10.1111/j.1600-0404.2012.01656.x, PubMed 22360378
Pharmacokinetic variability of four newer antiepileptic drugs, lamotrigine, levetiracetam, oxcarbazepine, and topiramate: a comparison of the impact of age and comedication
Ther Drug Monit, 34 (4), 440-5
DOI 10.1097/FTD.0b013e31825ee389, PubMed 22777154
The effect of levetiracetam on focal nocturnal epileptiform activity during sleep--a placebo-controlled double-blind cross-over study
Epilepsy Behav, 24 (1), 44-8
DOI 10.1016/j.yebeh.2012.02.024, PubMed 22494796
Alpha frequency estimation in patients with epilepsy
Clin EEG Neurosci, 43 (2), 97-104
DOI 10.1177/1550059411433611, PubMed 22715482
DETECTION OF DIRECT CAUSAL EFFECTS AND APPLICATION TO EPILEPTIC ELECTROENCEPHALOGRAM ANALYSIS
Int. J. Bifurcation Chaos, 22 (9), 1250222
DOI 10.1142/S0218127412502227
Fast evaluation of interictal spikes in long-term EEG by hyper-clustering
Epilepsia, 53 (7), 1196-204
DOI 10.1111/j.1528-1167.2012.03503.x, PubMed 22578143
Publications 2011
Acute postoperative seizures after epilepsy surgery - a long-term outcome predictor?
Acta Neurol Scand, 123 (1), 48-53
DOI 10.1111/j.1600-0404.2010.01343.x, PubMed 20199515
Levetiracetam reduces the frequency of interictal epileptiform discharges during NREM sleep in children with ADHD
Eur J Paediatr Neurol, 15 (6), 532-8
DOI 10.1016/j.ejpn.2011.04.014, PubMed 21683631
[The prescription registry and abuse of pregabalin]
Tidsskr Nor Laegeforen, 131 (3), 223
DOI 10.4045/tidsskr.10.1328, PubMed 21304565
Prescription patterns of antiepileptic drugs in patients with epilepsy in a nation-wide population
Epilepsy Res, 95 (1-2), 51-9
DOI 10.1016/j.eplepsyres.2011.02.012, PubMed 21435840
[Clarification about pregabalin and the Norwegian Prescription Database]
Tidsskr Nor Laegeforen, 131 (8), 800-1
DOI 10.4045/tidsskr.11.0292, PubMed 21556068
Reducing the bias of causality measures
Phys Rev E Stat Nonlin Soft Matter Phys, 83 (3 Pt 2), 036207
DOI 10.1103/PhysRevE.83.036207, PubMed 21517575
Feasibility of long-term continuous EEG monitoring during the first days of life in preterm infants: an automated quantification of the EEG activity
Pediatr Res, 69 (5 Pt 1), 413-7
DOI 10.1203/PDR.0b013e31821267d2, PubMed 21283050
Comparison of three methods for localizing interictal epileptiform discharges with magnetoencephalography
J Clin Neurophysiol, 28 (5), 431-40
DOI 10.1097/WNP.0b013e318231c86f, PubMed 21946369
Publications 2010
Psychiatric comorbidity in patients with epilepsy: a population-based study
Eur J Clin Pharmacol, 66 (11), 1151-60
DOI 10.1007/s00228-010-0861-y, PubMed 20669014
Decrease in propagation of interictal epileptiform activity after introduction of levetiracetam visualized with electric source imaging
Brain Topogr, 23 (3), 269-78
DOI 10.1007/s10548-010-0150-1, PubMed 20574764
Do sleep-deprived EEG recordings reflect spike index as found in full-night EEG recordings?
Epilepsy Behav, 19 (3), 348-51
DOI 10.1016/j.yebeh.2010.07.021, PubMed 20934918
Attention-deficit hyperactivity disorder and nocturnal epileptiform activity in children with epilepsy admitted to a national epilepsy center
Epilepsy Behav, 18 (4), 445-9
DOI 10.1016/j.yebeh.2010.05.013, PubMed 20598646
Publications 2009
Antiepileptic drugs in epilepsy and other disorders--a population-based study of prescriptions
Epilepsy Res, 87 (1), 31-9
DOI 10.1016/j.eplepsyres.2009.07.005, PubMed 19679449
Publications 2008
A new method for quantification and assessment of epileptiform activity in EEG with special reference to focal nocturnal epileptiform activity
Brain Topogr, 22 (1), 52-9
DOI 10.1007/s10548-008-0072-3, PubMed 19005748
Health-related quality of life in a trial of acupuncture, sham acupuncture and conventional treatment for chronic sinusitis
BMC Res Notes, 1, 37
DOI 10.1186/1756-0500-1-37, PubMed 18710490
Publications 2007
Is vagus nerve stimulation a treatment option for patients with drug-resistant idiopathic generalized epilepsy?
Acta Neurol Scand Suppl, 187, 55-8
DOI 10.1111/j.1600-0404.2007.00848.x, PubMed 17419830
Publications 2006
The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients
Epilepsy Res, 69 (1), 80-6
DOI 10.1016/j.eplepsyres.2006.01.001, PubMed 16516443
Time series feature evaluation in discriminating preictal EEG states
LECT NOTES COMPUT SC, 4345, 298-+
Reliability, validity and responsiveness of a Norwegian version of the Chronic Sinusitis Survey
BMC Ear Nose Throat Disord, 6, 9
DOI 10.1186/1472-6815-6-9, PubMed 16677392
Publications 2005
3T phased array MRI improves the presurgical evaluation in focal epilepsies: a prospective study
Neurology, 65 (7), 1026-31
DOI 10.1212/01.wnl.0000179355.04481.3c, PubMed 16217054
Lower frequency variability in the alpha activity in EEG among patients with epilepsy
Clin Neurophysiol, 116 (11), 2701-6
DOI 10.1016/j.clinph.2005.07.019, PubMed 16221562
Comparison of traditional Chinese acupuncture, minimal acupuncture at non-acupoints and conventional treatment for chronic sinusitis
Complement Ther Med, 13 (1), 4-10
DOI 10.1016/j.ctim.2005.01.002, PubMed 15907672
Publications 2000
Acupuncture in intractable epilepsy: lack of effect on health-related quality of life
Seizure, 9 (6), 422-6
DOI 10.1053/seiz.2000.0436, PubMed 10986000
Publications 1999
The effect of acupuncture in chronic intractable epilepsy
Seizure, 8 (3), 170-4
DOI 10.1053/seiz.1999.0278, PubMed 10356376
Publications 1998
Electrophysiological localization of brain regions involved in perceptual memory
Exp Brain Res, 123 (4), 481-4
DOI 10.1007/s002210050592, PubMed 9870607
Publications 1997
Simulation of the influence of different factors on the motor nerve condition velocity measurement. Part 1: Normal conditions
Electromyogr Clin Neurophysiol, 37 (3), 177-84
PubMed 9187868
Simulation of the influence of different factors on the motor nerve conduction velocity measurement. Part 2: Pathological conditions
Electromyogr Clin Neurophysiol, 37 (4), 195-9
PubMed 9208213
Does physical exercise influence the occurrence of epileptiform EEG discharges in children?
Epilepsia, 38 (3), 279-84
DOI 10.1111/j.1528-1157.1997.tb01118.x, PubMed 9070589
Publications 1994
Neuropsychological findings in a non-clinical sample of workers exposed to solvents
J Neurol Neurosurg Psychiatry, 57 (5), 614-6
DOI 10.1136/jnnp.57.5.614, PubMed 8201335
Publications 1992
[Topographic survey of the cerebral electric activity]
Tidsskr Nor Laegeforen, 112 (16), 2121
PubMed 1523642
Publications 1990
Influence of intravenous local anaesthetics upon quadriceps muscle function
Acta Anaesthesiol Scand, 34 (5), 393-6
DOI 10.1111/j.1399-6576.1990.tb03109.x, PubMed 2389655
Muscular load levels in performing musicians as monitored by quantitative electromyography
Med probl perform ar, 5 (2), 79-82
PublikaID 113
Publications 1989
Motor blockade and EMG recordings in epidural anaesthesia. A comparison between mepivacaine 2%, bupivacaine 0.5% and etidocaine 1.5%
Acta Anaesthesiol Scand, 33 (7), 597-604
DOI 10.1111/j.1399-6576.1989.tb02974.x, PubMed 2683548
Publications 1988
H reflex, F response and quantitative stretch reflex measurements in the lower extremity before and after intravenous infusion of local anaesthetics
Electromyogr Clin Neurophysiol, 28 (1), 15-20
PubMed 3168911
Evaluation of motor blockade by isometric force measurement and electromyographic recording during epidural anaesthesia--a methodological study
Acta Anaesthesiol Scand, 32 (6), 477-84
DOI 10.1111/j.1399-6576.1988.tb02770.x, PubMed 2972155
The electromyographic signal as a measure of muscular force: a comparison of detection and quantification techniques
Electromyogr Clin Neurophysiol, 28 (2-3), 141-50
PubMed 3416804
Publications 1981
A computer programme for the evaluation of dose response data
NIPH ann, 4 (1), 19-31
PublikaID 112
Antibiotic susceptibility pattern of community strains of the genus Staphylococcus with special reference to S saprophyticus
NIPH Ann, 4 (2), 61-8
PubMed 6977734
Publications 1979
The antitumour agent 5-(3,3-dimethyl-1-triazeno) imidazole-4-carboxamide (DTIC) inhibits rat liver cAMP phosphodiesterase and amplifies hormone effects in hepatocytes and hepatoma cells
Br J Cancer, 40 (5), 768-73
DOI 10.1038/bjc.1979.259, PubMed 228692