Therese Seierstad
- Head of research; PhD
- +47 464 51 987
Publications 2024
Spatial analysis of microRNA regulation at defined tumor hypoxia levels reveals biological traits of aggressive prostate cancer
J Pathol, 264 (3), 270-283
DOI 10.1002/path.6344, PubMed 39329425
Publications 2023
Impact of human telomerase reverse transcriptase peptide vaccine combined with androgen deprivation therapy and radiotherapy in de novo metastatic prostate cancer: Long-term clinical monitoring
Int J Cancer, 152 (10), 2166-2173
DOI 10.1002/ijc.34448, PubMed 36715014
MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
Cancers (Basel), 15 (18)
DOI 10.3390/cancers15184662, PubMed 37760629
Monoparametric high-resolution diffusion weighted MRI as a possible first step in an MRI-directed diagnostic pathway for men with suspicion of prostate cancer
Front Oncol, 13, 1102860
DOI 10.3389/fonc.2023.1102860, PubMed 36798813
Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
Radiother Oncol, 188, 109875
DOI 10.1016/j.radonc.2023.109875, PubMed 37640161
Publications 2022
Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
Cancers (Basel), 14 (5)
DOI 10.3390/cancers14051326, PubMed 35267636
A Prospective Study of High Dose-Rate Brachytherapy or Stereotactic Body Radiotherapy of Intra-Prostatic Recurrence: Toxicity and Long Term Clinical Outcome
Front Oncol, 12, 861127
DOI 10.3389/fonc.2022.861127, PubMed 35463376
A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients
Br J Cancer, 127 (2), 321-328
DOI 10.1038/s41416-022-01782-x, PubMed 35332267
Prognostic significance of conventional and volumetric PET parameters with and without partial volume correction in the assessment of head and neck squamous cell carcinoma
Nucl Med Commun, 43 (7), 800-806
DOI 10.1097/MNM.0000000000001573, PubMed 35552334
Publications 2021
Prostate-Specific Membrane Antigen PET for Assessment of Primary and Recurrent Prostate Cancer with Histopathology as Reference Standard: A Systematic Review and Meta-Analysis
PET Clin, 16 (2), 147-165
DOI 10.1016/j.cpet.2020.12.001, PubMed 33648661
Localization of primary prostate cancer: FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard
Am J Nucl Med Mol Imaging, 11 (5), 387-394
PubMed 34754609
MRI-based automatic segmentation of rectal cancer using 2D U-Net on two independent cohorts
Acta Oncol, 61 (2), 255-263
DOI 10.1080/0284186X.2021.2013530, PubMed 34918621
Results from a PI-RADS-based MRI-directed diagnostic pathway for biopsy-naive patients in a non-university hospital
Abdom Radiol (NY), 46 (12), 5639-5646
DOI 10.1007/s00261-021-03249-8, PubMed 34417637
Multimodal functional imaging for early response assessment in patients with gastrointestinal stromal tumor treated with tyrosine kinase inhibitors
Acta Radiol, 63 (8), 995-1004
DOI 10.1177/02841851211027389, PubMed 34171968
18F-Fluciclovine PET for Assessment of Prostate Cancer with Histopathology as Reference Standard: A Systematic Review
PET Clin, 16 (2), 167-176
DOI 10.1016/j.cpet.2020.12.012, PubMed 33648662
Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
Am J Nucl Med Mol Imaging, 11 (4), 250-259
PubMed 34513278
Publications 2020
Impact of radiation dose on recurrence in high-risk prostate cancer patients
Prostate, 80 (15), 1322-1327
DOI 10.1002/pros.24059, PubMed 33258482
Inter-reader agreement of 18F-FDG PET/CT for the quantification of carotid artery plaque inflammation
JRSM Cardiovasc Dis, 9, 2048004020980941
DOI 10.1177/2048004020980941, PubMed 33403110
Publications 2019
High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
BMC Cancer, 19 (1), 488
DOI 10.1186/s12885-019-5724-z, PubMed 31122213
Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
Cancer Immunol Immunother, 69 (3), 355-364
DOI 10.1007/s00262-019-02458-x, PubMed 31893287
Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Cancer Res, 79 (16), 4293-4304
DOI 10.1158/0008-5472.CAN-18-1804, PubMed 31118201
Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
Clin Transl Radiat Oncol, 21, 5-10
DOI 10.1016/j.ctro.2019.11.006, PubMed 31872084
PTEN Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings
AJR Am J Roentgenol, 212 (6), 1206-1214
DOI 10.2214/AJR.18.20743, PubMed 30888866
Publications 2018
Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
Transl Oncol, 12 (1), 76-83
DOI 10.1016/j.tranon.2018.09.010, PubMed 30273860
Local failure is a dominant mode of recurrence in locally advanced and clinical node positive prostate cancer patients treated with combined pelvic IMRT and androgen deprivation therapy
Urol Oncol, 37 (4), 289.e19-289.e26
DOI 10.1016/j.urolonc.2018.09.016, PubMed 30446451
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958
Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
Br J Cancer, 118 (10), 1322-1328
DOI 10.1038/s41416-018-0085-y, PubMed 29695770
Localization of radio-recurrence within the prostate: anti-3-18F-FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard
Acta Radiol, 60 (8), 1028-1038
DOI 10.1177/0284185118810977, PubMed 30379559
Comparison of time curves from dynamic 18F-fluciclovine positron emission tomography and dynamic contrast-enhanced magnetic resonance imaging for primary prostate carcinomas
Phys Imaging Radiat Oncol, 7, 51-57
DOI 10.1016/j.phro.2018.09.003, PubMed 33458405
Publications 2017
Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival
Acta Oncol, 56 (6), 813-818
DOI 10.1080/0284186X.2017.1287951, PubMed 28464745
Growth rates of pulmonary metastases after liver transplantation for unresectable colorectal liver metastases
Br J Surg, 105 (3), 295-301
DOI 10.1002/bjs.10651, PubMed 29168565
18F-FDG PET/CT for the quantification of inflammation in large carotid artery plaques
J Nucl Cardiol, 26 (3), 883-893
DOI 10.1007/s12350-017-1121-7, PubMed 29209949
Publications 2016
Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome
Clin Oncol (R Coll Radiol), 28 (8), 532-9
DOI 10.1016/j.clon.2016.01.014, PubMed 26888115
Individual tumor volume responses to short-course oxaliplatin-containing induction chemotherapy in locally advanced rectal cancer - Targeting the tumor for radiation sensitivity?
Radiother Oncol, 119 (3), 505-11
DOI 10.1016/j.radonc.2016.02.020, PubMed 26968754
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
Br J Cancer, 115 (8), 929-939
DOI 10.1038/bjc.2016.278, PubMed 27599042
Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
Eur J Cancer, 70, 122-132
DOI 10.1016/j.ejca.2016.10.011, PubMed 27914242
Publications 2015
Measurements of carotid intima media thickness in non-invasive high-frequency ultrasound images: the effect of dynamic range setting
Cardiovasc Ultrasound, 13, 5
DOI 10.1186/1476-7120-13-5, PubMed 25628215
High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer
Radiother Oncol, 118 (2), 393-8
DOI 10.1016/j.radonc.2015.11.031, PubMed 26705680
MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer
Br J Radiol, 88 (1051), 20150097
DOI 10.1259/bjr.20150097, PubMed 25899892
Identification of prostate cancer biomarkers in urinary exosomes
Oncotarget, 6 (30), 30357-76
DOI 10.18632/oncotarget.4851, PubMed 26196085
Publications 2014
Standardized cine-loop documentation in renal ultrasound facilitates skill-mix between radiographer and radiologist
Acta Radiol, 56 (3), 368-73
DOI 10.1177/0284185114527868, PubMed 24615418
Diffusion-weighted MRI compared to FDG PET/CT for assessment of early treatment response in lymphoma
Acta Radiol, 56 (2), 152-8
DOI 10.1177/0284185114526087, PubMed 24585944
Associations between tumor vascularization assessed by in vivo DCE-MRI and the presence of disseminated tumor cells in bone marrow in breast cancer patients at the time of diagnosis
J Magn Reson Imaging, 40 (6), 1382-91
DOI 10.1002/jmri.24502, PubMed 24470360
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
Br J Cancer, 112 (2), 382-90
DOI 10.1038/bjc.2014.604, PubMed 25461803
Radiotherapy for spinal metastases from breast cancer with emphasis on local disease control and pain response using repeated MRI
J Bone Oncol, 3 (1), 5-9
DOI 10.1016/j.jbo.2014.02.003, PubMed 26909292
Publications 2013
Dynamic (18) F-FDG PET for Assessment of Tumor Physiology in Two Breast Carcinoma Xenografts
Nucl Med Mol Imaging, 47 (3), 173-80
DOI 10.1007/s13139-013-0211-y, PubMed 24900104
Dynamic (18)F-FDG-PET for monitoring treatment effect following anti-angiogenic therapy in triple-negative breast cancer xenografts
Acta Oncol, 52 (7), 1566-72
DOI 10.3109/0284186X.2013.813634, PubMed 23984812
Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer
Int J Radiat Oncol Biol Phys, 87 (4), 753-60
DOI 10.1016/j.ijrobp.2013.07.023, PubMed 24035332
Multimodal functional imaging for early response assessment in GIST patients treated with imatinib
Acta Oncol, 53 (1), 143-8
DOI 10.3109/0284186X.2013.798428, PubMed 23710697
Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H
Acta Oncol, 52 (4), 776-82
DOI 10.3109/0284186X.2013.770920, PubMed 23480638
Publications 2012
Reject analysis in direct digital radiography
Acta Radiol, 53 (2), 174-8
DOI 10.1258/ar.2011.110350, PubMed 22287147
Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance
Eur Radiol, 23 (4), 1158-66
DOI 10.1007/s00330-012-2669-x, PubMed 23114883
Quantitative analysis of diffusion-weighted magnetic resonance imaging in malignant breast lesions using different b value combinations
Eur Radiol, 23 (4), 1027-33
DOI 10.1007/s00330-012-2687-8, PubMed 23111816
MRI and neurological findings in patients with spinal metastases
Acta Radiol, 53 (10), 1164-72
DOI 10.1258/ar.2012.120442, PubMed 23047848
Publications 2011
G-CSF enhances the proliferation and mobilization, but not the maturation rate, of murine myeloid cells
Eur J Haematol, 87 (4), 302-11
DOI 10.1111/j.1600-0609.2011.01658.x, PubMed 21623923
Monitoring the effect of targeted therapies in a gastrointestinal stromal tumor xenograft using a clinical PET/CT
Mol Imaging Biol, 13 (6), 1234-40
DOI 10.1007/s11307-010-0464-0, PubMed 21161686
Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study
Radiat Oncol, 6, 65
DOI 10.1186/1748-717X-6-65, PubMed 21651782
Radiation doses to Norwegian heart-transplanted patients undergoing annual coronary angiography
Radiat Prot Dosimetry, 149 (4), 403-9
DOI 10.1093/rpd/ncr311, PubMed 21775318
Publications 2010
Neoadjuvant chemotherapy in breast cancer-response evaluation and prediction of response to treatment using dynamic contrast-enhanced and diffusion-weighted MR imaging
Eur Radiol, 21 (6), 1188-99
DOI 10.1007/s00330-010-2020-3, PubMed 21127880
Diffusion-weighted magnetic resonance imaging for pretreatment prediction and monitoring of treatment response of patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy
Acta Oncol, 49 (3), 354-60
DOI 10.3109/02841861003610184, PubMed 20397769
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study
Lancet Oncol, 11 (5), 459-64
DOI 10.1016/S1470-2045(10)70058-9, PubMed 20378407
DW MRI for evaluation of treatment response to imatinib in a rectal gastrointestinal stromal tumour
Acta Oncol, 50 (1), 148-50
DOI 10.3109/0284186X.2010.516273, PubMed 21110775
Preclinical dynamic 18F-FDG PET - tumor characterization and radiotherapy response assessment by kinetic compartment analysis
Acta Oncol, 49 (7), 914-21
DOI 10.3109/0284186X.2010.498831, PubMed 20831478
Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditions
Neoplasia, 12 (10), 818-25
DOI 10.1593/neo.10484, PubMed 20927320
Publications 2009
Artificial neural networks for prediction of response to chemoradiation in HT29 xenografts
Int J Radiat Oncol Biol Phys, 75 (2), 506-11
DOI 10.1016/j.ijrobp.2009.05.036, PubMed 19735875
Establishment and characterization of a human gastrointestinal stromal tumour (GIST) xenograft in athymic nude mice
Anticancer Res, 29 (11), 4331-6
PubMed 20032375
MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy
Radiother Oncol, 93 (2), 279-84
DOI 10.1016/j.radonc.2009.08.046, PubMed 19800704
Publications 2008
Magnetic resonance spectroscopy and diffusion for prediction and monitoring of treatment response in rectal cancer
In Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo, The Faculty, Oslo, nr. 711, 1 b. (flere pag.)
BIBSYS 080525237
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy
Mol Cancer, 7, 33
DOI 10.1186/1476-4598-7-33, PubMed 18439252
Publications 2007
Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity?
Radiother Oncol, 86 (3), 428-34
DOI 10.1016/j.radonc.2007.10.012, PubMed 18006097
Early changes in apparent diffusion coefficient predict the quantitative antitumoral activity of capecitabine, oxaliplatin, and irradiation in HT29 xenografts in athymic nude mice
Neoplasia, 9 (5), 392-400
DOI 10.1593/neo.07154, PubMed 17534444
Construction of a modified capacitive overlap MR coil for imaging of small animals and objects in a clinical whole-body scanner
Phys Med Biol, 52 (22), N513-22
DOI 10.1088/0031-9155/52/22/N02, PubMed 17975281
Noninvasive monitoring of radiation-induced treatment response using proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging in a colorectal tumor model
Radiother Oncol, 85 (2), 187-94
DOI 10.1016/j.radonc.2007.09.009, PubMed 17937968
Publications 2006
Doses to nuclear technicians in a dedicated PET/CT centre utilising 18F fluorodeoxyglucose (FDG)
Radiat Prot Dosimetry, 123 (2), 246-9
DOI 10.1093/rpd/ncl141, PubMed 16987913
Publications 2004
Macrophages in spleen and liver direct the migration pattern of rat neutrophils during inflammation
Eur J Haematol, 73 (2), 109-22
DOI 10.1111/j.1600-0609.2004.00263.x, PubMed 15245510
Publications 2003
Effects of photon attenuation on the determination of cardiac volumes from reconstructed counts in gated blood pool SPET
Eur J Nucl Med Mol Imaging, 31 (3), 399-402
DOI 10.1007/s00259-003-1335-6, PubMed 14691609
Publications 1997
Cloning, functional activities and in vivo tissue distribution of rat NKR-P1+ TCR alpha beta + cells
Int Immunol, 9 (7), 1043-51
DOI 10.1093/intimm/9.7.1043, PubMed 9237113
Leukocyttkinetikk hos rotter: En studie av merkede, intravenøst injiserte naturlige T-celler i normale, friske dyr
Fak. for fysikk, informatikk og matematikk, NTNU, Trondheim, 73, 23, 6 bl
BIBSYS 061906174