Karl-Otto Larsen

  • Associate Professor
 

Publications 2024

Udjus C, Halvorsen B, Kong XY, Sagen EL, Martinsen M, Yang K, Løberg EM, Christensen G, Skjønsberg OH, Larsen KO (2024)
Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs
Physiol Rep, 12 (14), e16143
DOI 10.14814/phy2.16143, PubMed 39034131

Publications 2022

Udjus C, Sjaastad I, Hjørnholm U, Tunestveit TK, Hoffmann P, Hinojosa A, Espe EKS, Christensen G, Skjønsberg OH, Larsen KO, Rostrup M (2022)
Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers
Physiol Rep, 10 (3), e15184
DOI 10.14814/phy2.15184, PubMed 35146955

Publications 2020

Thorsen L, Haugnes HS, Fosså SD, Brydøy M, Tandstad T, Wisløff T, Gjerset GM, Edvardsen E, Larsen KO, Sandset PM, Henriksson CE, Raastad T, Negaard HFS (2020)
Thromboembolic events after high-intensity training during cisplatin-based chemotherapy for testicular cancer: Case reports and review of the literature
Int J Cancer, 147 (11), 3189-3198
DOI 10.1002/ijc.33151, PubMed 32525564

Publications 2019

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Løberg EM, Yndestad A, Aukrust P, Christensen G, Skjønsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936

Publications 2015

Cero FT, Hillestad V, Sjaastad I, Yndestad A, Aukrust P, Ranheim T, Lunde IG, Olsen MB, Lien E, Zhang L, Haugstad SB, Løberg EM, Christensen G, Larsen KO, Skjønsberg OH (2015)
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556

Publications 2014

Hillestad V, Espe EK, Cero F, Larsen KO, Sjaastad I, Nygård S, Skjønsberg OH, Christensen G (2014)
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
DOI 10.1111/apha.12376, PubMed 25182570

Publications 2012

Cero FT, Hillestad V, Løberg EM, Christensen G, Larsen KO, Skjønsberg OH (2012)
IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung
Exp Lung Res, 38 (8), 406-19
DOI 10.3109/01902148.2012.716903, PubMed 22908875

Larsen KO (2012)
Utredning av dyspné – lunge- eller hjertesykdom?
BestPractice, 2, 20-21
PublikaID 155

Publications 2011

Larsen KO (2011)
Belastningsundersøkelse for vurdering av kardiopulmonal funksjon
3, 24, 17-25
PublikaID 154

Larsen KO, Yndestad A, Sjaastad I, Løberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjønsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626

Publications 2010

Larsen KO (2010)
Pulmonary hypertension and cardiac dysfunction: the role of hypoxia and cytokines
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 1030, 1 b. (flere pag.)
BIBSYS 102720975, ISBN 978-82-8072-526-4

Larsen KO (2010)
Pulmonary hypertension and cardiac dysfunction; the role of hypoxia and cytokines
Faculty of medicine, University of Oslo
PublikaID 103, ISBN 978-82-8072-526-4

Publications 2009

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjønsberg OH, Pedersen TM, Anfinsen OG, Damås JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
DOI 10.1152/japplphysiol.90719.2008, PubMed 19196915

Publications 2008

Larsen KO, Lygren B, Sjaastad I, Krobert KA, Arnkvaern K, Florholmen G, Larsen AK, Levy FO, Taskén K, Skjønsberg OH, Christensen G (2008)
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A
Cardiovasc Res, 80 (1), 47-54
DOI 10.1093/cvr/cvn180, PubMed 18599478

Publications 2006

Larsen KO, Sjaastad I, Svindland A, Krobert KA, Skjønsberg OH, Christensen G (2006)
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice
Am J Physiol Heart Circ Physiol, 291 (2), H507-16
DOI 10.1152/ajpheart.00862.2005, PubMed 16582020

Publications 2000

Larsen KO, Stray N, Engh V, Sandnes D (2000)
[Esophageal lesions associated with diphosphonates]
Tidsskr Nor Laegeforen, 120 (20), 2397-9
PubMed 11475224