Yngve Sejersted

  • Unit leader | Medical geneticist; MD, PhD

Yngve Sejersted is an MD by training, with a specialization in medical genetics. He did his PhD on DNA repair mechanisms in brain stem cells in 2012. He is currently head of the Unit for Genome Diagnostics at the Department of Medical Genetics.

 

Publications 2023

Dahll LK, Westbye AB, Vinorum K, Sejersted Y, Barøy T, Thorsby PM, Hammerstad SS (2023)
Clinical and Biochemical Characteristics of Untreated Adult Patients With Resistance to Thyroid Hormone Alpha
J Endocr Soc, 7 (8), bvad089
DOI 10.1210/jendso/bvad089, PubMed 37469961

Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study
Epilepsy Res, 190, 107099
DOI 10.1016/j.eplepsyres.2023.107099, PubMed 36731270

Jamali A, Kristensen E, Tangeraas T, Arntsen V, Sikiric A, Kupliauskiene G, Myren-Svelstad S, Berland S, Sejersted Y, Gerstner T, Hassel B, Bindoff LA, Brodtkorb E (2023)
Corrigendum to "The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study" [Epilepsy Res. 190 (2023) 107099]
Epilepsy Res, 198, 107113
DOI 10.1016/j.eplepsyres.2023.107113, PubMed 36906427

Publications 2020

Henriksen MW, Breck H, Sejersted Y, Diseth T, von Tetzchner S, Paus B, Skjeldal OH (2020)
Genetic and clinical variations in a Norwegian sample diagnosed with Rett syndrome
Brain Dev, 42 (7), 484-495
DOI 10.1016/j.braindev.2020.03.008, PubMed 32336485

Publications 2019

Pope MK, Ratajska A, Johnsen H, Rypdal KB, Sejersted Y, Paus B (2019)
Diagnostics of Hereditary Connective Tissue Disorders by Genetic Next-Generation Sequencing
Genet Test Mol Biomarkers, 23 (11), 783-790
DOI 10.1089/gtmb.2019.0064, PubMed 31638417

Publications 2018

Rydning SL, Dudesek A, Rimmele F, Funke C, Krüger S, Biskup S, Vigeland MD, Hjorthaug HS, Sejersted Y, Tallaksen C, Selmer KK, Kamm C (2018)
A novel heterozygous variant in ERLIN2 causes autosomal dominant pure hereditary spastic paraplegia
Eur J Neurol, 25 (7), 943-e71
DOI 10.1111/ene.13625, PubMed 29528531

Publications 2015

Ystgaard MB, Sejersted Y, Løberg EM, Lien E, Yndestad A, Saugstad OD (2015)
Early Upregulation of NLRP3 in the Brain of Neonatal Mice Exposed to Hypoxia-Ischemia: No Early Neuroprotective Effects of NLRP3 Deficiency
Neonatology, 108 (3), 211-9
DOI 10.1159/000437247, PubMed 26279061

Publications 2014

Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, Nygård S, Saugstad OD, Pietrzyk JJ (2014)
Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
Invest Ophthalmol Vis Sci, 55 (3), 1393-401
DOI 10.1167/iovs.13-13159, PubMed 24458145

Publications 2013

Rolseth V, Krokeide SZ, Kunke D, Neurauter CG, Suganthan R, Sejersted Y, Hildrestrand GA, Bjørås M, Luna L (2013)
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress
Biochim Biophys Acta, 1833 (5), 1157-64
DOI 10.1016/j.bbamcr.2012.12.024, PubMed 23305905

Wollen EJ, Sejersted Y, Wright MS, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Nygård S, Kwinta P, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
DOI 10.1038/pr.2013.140, PubMed 23999071

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083

Publications 2012

Odland HH, Brun H, Sejersted Y, Dalen M, Edvardsen T, Saugstad OD, Thaulow E (2012)
Myocardial longitudinal peak systolic acceleration (pSac): relationship to ejection phase, pressure, and contractility
Echocardiography, 29 (5), 541-53
DOI 10.1111/j.1540-8175.2011.01628.x, PubMed 22329750

Regnell CE, Hildrestrand GA, Sejersted Y, Medin T, Moldestad O, Rolseth V, Krokeide SZ, Suganthan R, Luna L, Bjørås M, Bergersen LH (2012)
Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells
Cell Rep, 2 (3), 503-10
DOI 10.1016/j.celrep.2012.08.008, PubMed 22959434

Saugstad OD, Sejersted Y, Solberg R, Wollen EJ, Bjørås M (2012)
Oxygenation of the newborn: a molecular approach
Neonatology, 101 (4), 315-25
DOI 10.1159/000337345, PubMed 22940621

Publications 2011

Odland HH, Brun H, Sejersted Y, Dalen M, Edvardsen T, Saugstad OD, Thaulow E (2011)
Longitudinal myocardial contribution to peak systolic flow and stroke volume in the neonatal heart
Pediatr Res, 70 (4), 345-51
DOI 10.1203/PDR.0b013e318229032b, PubMed 21691252

Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M (2011)
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
DOI 10.1073/pnas.1106880108, PubMed 22065741

Publications 2009

Sejersted Y, Aasland AL, Bjørås M, Eide L, Saugstad OD (2009)
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice
Pediatr Res, 66 (5), 533-8
DOI 10.1203/PDR.0b013e3181ba1a42, PubMed 19668103