Yngve Sejersted
- Unit leader | Medical geneticist; MD, PhD
Yngve Sejersted is an MD by training, with a specialization in medical genetics. He did his PhD on DNA repair mechanisms in brain stem cells in 2012. He is currently head of the Unit for Genome Diagnostics at the Department of Medical Genetics.
Publications 2023
Clinical and Biochemical Characteristics of Untreated Adult Patients With Resistance to Thyroid Hormone Alpha
J Endocr Soc, 7 (8), bvad089
DOI 10.1210/jendso/bvad089, PubMed 37469961
The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study
Epilepsy Res, 190, 107099
DOI 10.1016/j.eplepsyres.2023.107099, PubMed 36731270
Corrigendum to "The spectrum of pyridoxine dependent epilepsy across the age span: A nationwide retrospective observational study" [Epilepsy Res. 190 (2023) 107099]
Epilepsy Res, 198, 107113
DOI 10.1016/j.eplepsyres.2023.107113, PubMed 36906427
Publications 2020
Genetic and clinical variations in a Norwegian sample diagnosed with Rett syndrome
Brain Dev, 42 (7), 484-495
DOI 10.1016/j.braindev.2020.03.008, PubMed 32336485
Publications 2019
Diagnostics of Hereditary Connective Tissue Disorders by Genetic Next-Generation Sequencing
Genet Test Mol Biomarkers, 23 (11), 783-790
DOI 10.1089/gtmb.2019.0064, PubMed 31638417
Publications 2018
A novel heterozygous variant in ERLIN2 causes autosomal dominant pure hereditary spastic paraplegia
Eur J Neurol, 25 (7), 943-e71
DOI 10.1111/ene.13625, PubMed 29528531
Publications 2015
Early Upregulation of NLRP3 in the Brain of Neonatal Mice Exposed to Hypoxia-Ischemia: No Early Neuroprotective Effects of NLRP3 Deficiency
Neonatology, 108 (3), 211-9
DOI 10.1159/000437247, PubMed 26279061
Publications 2014
Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
Invest Ophthalmol Vis Sci, 55 (3), 1393-401
DOI 10.1167/iovs.13-13159, PubMed 24458145
Publications 2013
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress
Biochim Biophys Acta, 1833 (5), 1157-64
DOI 10.1016/j.bbamcr.2012.12.024, PubMed 23305905
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
DOI 10.1038/pr.2013.140, PubMed 23999071
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
DOI 10.1038/pr.2013.249, PubMed 24375083
Publications 2012
Myocardial longitudinal peak systolic acceleration (pSac): relationship to ejection phase, pressure, and contractility
Echocardiography, 29 (5), 541-53
DOI 10.1111/j.1540-8175.2011.01628.x, PubMed 22329750
Hippocampal adult neurogenesis is maintained by Neil3-dependent repair of oxidative DNA lesions in neural progenitor cells
Cell Rep, 2 (3), 503-10
DOI 10.1016/j.celrep.2012.08.008, PubMed 22959434
Oxygenation of the newborn: a molecular approach
Neonatology, 101 (4), 315-25
DOI 10.1159/000337345, PubMed 22940621
Publications 2011
Longitudinal myocardial contribution to peak systolic flow and stroke volume in the neonatal heart
Pediatr Res, 70 (4), 345-51
DOI 10.1203/PDR.0b013e318229032b, PubMed 21691252
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
DOI 10.1073/pnas.1106880108, PubMed 22065741
Publications 2009
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice
Pediatr Res, 66 (5), 533-8
DOI 10.1203/PDR.0b013e3181ba1a42, PubMed 19668103