Morten C. Eike

  • Senior engineer; PhD, MA

Morten C. Eike has a diverse background, with a PhD in human genetics and an MA in interdisciplinary studies. He has taken a special interest in the use of high-throughput DNA sequencing methods in a clinical setting. This has resulted in a key role in the development of the open source software tool ELLA, which is also his current main focus.

 

Publications 2022

Välikangas T, Lietzén N, Jaakkola MK, Krogvold L, Eike MC, Kallionpää H, Tuomela S, Mathews C, Gerling IC, Oikarinen S, Hyöty H, Dahl-Jorgensen K, Elo LL, Lahesmaa R (2022)
Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes
Front Endocrinol (Lausanne), 13, 861985
DOI 10.3389/fendo.2022.861985, PubMed 35498413

Publications 2016

Borsting J, Culen AL, Eike MC (2016)
AIDING GENETIC ANALYSTS: DESIGN OF A LITERATURE EVALUATION SYSTEM
IADIS-Int. J. Comput. Sci. Inf. Syst., 11 (1), 1-16

Publications 2015

Borsting J, Culen AL, Eike MC (2015)
DESIGN OF A REFERENCE HANDLING SYSTEM FOR CLINICAL DNA SEQUENCING ANALYSIS
PROCEEDINGS OF THE INTERNATIONAL CONFERENCES ON E-HEALTH 2015 E-COMMERCE AND DIGITAL MARKETING 2015 AND INFORMATION SYSTEMS POST-IMPLEMENTATION AND CHANGE MANAGEMENT 2015, 79-87

Publications 2014

Krogvold L, Edwin B, Buanes T, Frisk G, Skog O, Anagandula M, Korsgren O, Undlien D, Eike MC, Richardson SJ, Leete P, Morgan NG, Oikarinen S, Oikarinen M, Laiho JE, Hyöty H, Ludvigsson J, Hanssen KF, Dahl-Jørgensen K (2014)
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
Diabetes, 64 (5), 1682-7
DOI 10.2337/db14-1370, PubMed 25422108

Publications 2012

Eike MC, Skinningsrud B, Ronninger M, Stormyr A, Kvien TK, Joner G, Njølstad PR, Førre O, Flatø B, Alfredsson L, Padyukov L, Undlien DE, Lie BA (2012)
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations
Genes Immun, 13 (5), 431-6
DOI 10.1038/gene.2012.11, PubMed 22513452

Ronninger M, Seddighzadeh M, Eike MC, Plant D, Daha NA, Skinningsrud B, Worthington J, Kvien TK, Toes RE, Lie BA, Alfredsson L, Padyukov L (2012)
Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis
PLoS One, 7 (3), e32861
DOI 10.1371/journal.pone.0032861, PubMed 22461888

Publications 2011

Forsetlund L, Eike MC, Gjerberg E, Vist GE (2011)
Effect of interventions to reduce potentially inappropriate use of drugs in nursing homes: a systematic review of randomised controlled trials
BMC Geriatr, 11, 16
DOI 10.1186/1471-2318-11-16, PubMed 21496345

Publications 2009

Eike MC, Humphreys K, Becker T, Olsson M, Lie BA, Type 1 Diabetes Genetics Consortium (2009)
Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes
Diabetes Obes Metab, 11 Suppl 1 (Suppl 1), 17-24
DOI 10.1111/j.1463-1326.2008.00999.x, PubMed 19143811

Publications 2008

Eike MC, Becker T, Humphreys K, Olsson M, Lie BA (2008)
Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B
Genes Immun, 10 (1), 56-67
DOI 10.1038/gene.2008.74, PubMed 18830248

Eike MC, Olsson M, Undlien DE, Dahl-Jørgensen K, Joner G, Rønningen KS, Thorsby E, Lie BA (2008)
Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families
Genes Immun, 10 (2), 141-50
DOI 10.1038/gene.2008.88, PubMed 18987644

Publications 2007

Eike MC, Nordang GB, Karlsen TH, Boberg KM, Vatn MH, IBSEN study group, Dahl-Jørgensen K, Rønningen KS, Joner G, Flatø B, Bergquist A, Thorsby E, Førre O, Kvien TK, Undlien DE, Lie BA (2007)
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann Rheum Dis, 67 (9), 1287-91
DOI 10.1136/ard.2007.077826, PubMed 18065500

Publications 2006

Skårn M, Eike MC, Meza TJ, Mercy IS, Jakobsen KS, Aalen RB (2006)
An inverted repeat transgene with a structure that cannot generate double-stranded RNA, suffers silencing independent of DNA methylation
Transgenic Res, 15 (4), 489-500
DOI 10.1007/s11248-006-0019-y, PubMed 16906449

Publications 2005

Eike MC, Mercy IS, Aalen RB (2005)
Transgene silencing may be mediated by aberrant sense promoter sequence transcripts generated from cryptic promoters
Cell Mol Life Sci, 62 (24), 3080-91
DOI 10.1007/s00018-005-5301-2, PubMed 16314927

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