Anne Dørum
- Senior consultant; MD, PhD
- +47 22 93 44 25
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Publications 2024
Evolutionary mode and timing of dissemination of high-grade serous carcinomas
JCI Insight, 9 (3)
DOI 10.1172/jci.insight.170423, PubMed 38175731
Publications 2023
Real-world data on niraparib maintenance treatment in patients with non-gBRCA mutated platinum-sensitive recurrent ovarian cancer
Int J Gynecol Cancer, 33 (12), 1898-1905
DOI 10.1136/ijgc-2023-004484, PubMed 38000795
Publications 2022
Symptomatic or asymptomatic recurrence of ovarian cancer: does it influence survival?
Int J Gynecol Cancer (in press)
DOI 10.1136/ijgc-2022-003361, PubMed 35680138
Efficacy of niraparib by time of surgery and postoperative residual disease status: A post hoc analysis of patients in the PRIMA/ENGOT-OV26/GOG-3012 study
Gynecol Oncol, 166 (1), 36-43
DOI 10.1016/j.ygyno.2022.04.012, PubMed 35550709
Publications 2021
Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer
Sci Rep, 11 (1), 23463
DOI 10.1038/s41598-021-02820-z, PubMed 34873230
Impact of MDM2 promoter SNP55 (rs2870820) on risk of endometrial and ovarian cancer
Biomarkers, 26 (4), 302-308
DOI 10.1080/1354750X.2021.1891291, PubMed 33645339
Long-term oncological outcomes and recurrence patterns in early-stage cervical cancer treated with minimally invasive versus abdominal radical hysterectomy: The Norwegian Radium Hospital experience
Gynecol Oncol, 162 (2), 284-291
DOI 10.1016/j.ygyno.2021.05.028, PubMed 34083029
Publications 2020
Long-term safety in patients with recurrent ovarian cancer treated with niraparib versus placebo: Results from the phase III ENGOT-OV16/NOVA trial
Gynecol Oncol, 159 (2), 442-448
DOI 10.1016/j.ygyno.2020.09.006, PubMed 32981695
Base rate of ovarian cancer on algorithms in patients with a pelvic mass
Int J Gynecol Cancer, 30 (11), 1775-1779
DOI 10.1136/ijgc-2020-001416, PubMed 32699016
Exploratory Analysis of CA125-MGL and -STn Glycoforms in the Differential Diagnostics of Pelvic Masses
J Appl Lab Med, 5 (2), 263-272
DOI 10.1093/jalm/jfz012, PubMed 32445385
Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology
Int J Mol Sci, 21 (21)
DOI 10.3390/ijms21217988, PubMed 33121141
Publications 2019
Efficacy and safety of niraparib as maintenance treatment in older patients (≥ 70 years) with recurrent ovarian cancer: Results from the ENGOT-OV16/NOVA trial
Gynecol Oncol, 152 (3), 560-567
DOI 10.1016/j.ygyno.2018.12.009, PubMed 30638768
Publications 2018
White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk
Ann Intern Med, 168 (5), 326-334
DOI 10.7326/M17-0101, PubMed 29335712
Publications 2017
MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
Oncotarget, 8 (37), 61800-61809
DOI 10.18632/oncotarget.18694, PubMed 28977905
MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
BMC Cancer, 17 (1), 97
DOI 10.1186/s12885-017-3094-y, PubMed 28158999
TGFβ splicing and canonical pathway activation in high-grade serous carcinoma
Virchows Arch, 470 (6), 665-678
DOI 10.1007/s00428-017-2127-x, PubMed 28432432
Use of hormone replacement therapy after risk-reducing salpingo-oophorectomy
Acta Obstet Gynecol Scand, 96 (5), 547-555
DOI 10.1111/aogs.13120, PubMed 28236297
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
PLoS One, 12 (7), e0182030
DOI 10.1371/journal.pone.0182030, PubMed 28759630
Chemotherapy vs tamoxifen in platinum-resistant ovarian cancer: a phase III, randomised, multicentre trial (Ovaresist)
Br J Cancer, 116 (4), 455-463
DOI 10.1038/bjc.2016.435, PubMed 28118323
A national, prospective observational study of first recurrence after primary treatment for gynecological cancer in Norway
Acta Obstet Gynecol Scand, 96 (10), 1162-1169
DOI 10.1111/aogs.13199, PubMed 28795770
Publications 2016
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancer
Tumour Biol, 37 (8), 10697-702
DOI 10.1007/s13277-016-4940-2, PubMed 26867771
Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer
N Engl J Med, 375 (22), 2154-2164
DOI 10.1056/NEJMoa1611310, PubMed 27717299
Publications 2015
Psychological distress related to BRCA testing in ovarian cancer patients
Fam Cancer, 14 (4), 495-504
DOI 10.1007/s10689-015-9811-2, PubMed 25980896
Publications 2012
Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers
BMC Cancer, 12, 454
DOI 10.1186/1471-2407-12-454, PubMed 23039163
MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk
PLoS One, 7 (4), e36263
DOI 10.1371/journal.pone.0036263, PubMed 22558411
Association between hysterectomy with ovarian preservation and cardiovascular disease in a Norwegian population-based sample
Gynecol Obstet Invest, 75 (1), 61-7
DOI 10.1159/000345072, PubMed 23220872
Publications 2011
"The impact of cancer scale" version 1: psychometric testing of the Norwegian translation in a heterogeneous sample of cancer survivors
Qual Life Res, 21 (8), 1459-70
DOI 10.1007/s11136-011-0053-y, PubMed 22045155
The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
Cancer Cell, 19 (2), 273-82
DOI 10.1016/j.ccr.2010.12.019, PubMed 21316605
Ovarian cancer in elderly patients: carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in late relapse: a Gynecologic Cancer Intergroup (GCIG) CALYPSO sub-study
Ann Oncol, 22 (11), 2417-2423
DOI 10.1093/annonc/mdr001, PubMed 21402619
Publications 2010
Coronary heart disease risk profile in women who underwent salpingo-oophorectomy to prevent hereditary breast ovarian cancer
Int J Gynecol Cancer, 20 (2), 233-9
DOI 10.1111/igc.0b013e3181ca5ff4, PubMed 20169665
Publications 2009
Morbidity associated with "self-rated health" in epithelial ovarian cancer survivors
BMC Cancer, 9, 2
DOI 10.1186/1471-2407-9-2, PubMed 19121203
Prevalence and determinants of metabolic syndrome and elevated Framingham risk score in epithelial ovarian cancer survivors: a controlled observational study
Int J Gynecol Cancer, 19 (4), 634-40
DOI 10.1111/IGC.0b013e3181a13058, PubMed 19509562
A controlled study of mental distress and somatic complaints after risk-reducing salpingo-oophorectomy in women at risk for hereditary breast ovarian cancer
Gynecol Oncol, 113 (1), 128-33
DOI 10.1016/j.ygyno.2008.12.024, PubMed 19178933
Fatigue and quality of life after risk-reducing salpingo-oophorectomy in women at increased risk for hereditary breast-ovarian cancer
Int J Gynecol Cancer, 19 (6), 1029-36
DOI 10.1111/IGC.0b013e3181a83cd5, PubMed 19820364
Publications 2008
Bilateral oophorectomy before 50 years of age is significantly associated with the metabolic syndrome and Framingham risk score: a controlled, population-based study (HUNT-2)
Gynecol Oncol, 109 (3), 377-83
DOI 10.1016/j.ygyno.2008.02.025, PubMed 18407340
Screening for familial ovarian cancer: poor survival of BRCA1/2 related cancers
J Med Genet, 46 (9), 593-7
DOI 10.1136/jmg.2008.058248, PubMed 18413372
Metabolic syndrome after risk-reducing salpingo-oophorectomy in women at high risk for hereditary breast ovarian cancer: a controlled observational study
Eur J Cancer, 45 (1), 82-9
DOI 10.1016/j.ejca.2008.09.028, PubMed 19008092
Publications 2007
A controlled study of sexual activity and functioning in epithelial ovarian cancer survivors. A therapeutic approach
Gynecol Oncol, 108 (2), 348-54
DOI 10.1016/j.ygyno.2007.10.009, PubMed 17996925
Controlled study of fatigue, quality of life, and somatic and mental morbidity in epithelial ovarian cancer survivors: how lucky are the lucky ones?
J Clin Oncol, 25 (15), 2049-56
DOI 10.1200/JCO.2006.09.1769, PubMed 17513809
Publications 2006
Chromosome 2q24.2 is lost in sporadic but not in BRCA1-associated ovarian carcinomas
Pathology, 38 (2), 145-51
DOI 10.1080/00313020600561526, PubMed 16680901
Ri antibodies in patients with breast, ovarian or small cell lung cancer determined by a sensitive immunoprecipitation technique
Cancer Immunol Immunother, 55 (10), 1280-4
DOI 10.1007/s00262-006-0121-2, PubMed 16429314
Yo antibodies in ovarian and breast cancer patients detected by a sensitive immunoprecipitation technique
Clin Exp Immunol, 144 (1), 53-8
DOI 10.1111/j.1365-2249.2006.03031.x, PubMed 16542365
A new approach to treatment of early-stage cervical carcinoma: entire laparoscopic abdominal radical hysterectomy with bilateral pelvic lymphadenectomy without vaginal cuff closure--case reports
Eur J Gynaecol Oncol, 27 (5), 513-8
PubMed 17139990
Publications 2005
Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions
Am J Clin Pathol, 123 (3), 360-8
DOI 10.1309/PTBB-5BPC-KX8K-9V69, PubMed 15716231
Prevalence and histologic diagnosis of adnexal cysts in postmenopausal women: an autopsy study
Am J Obstet Gynecol, 192 (1), 48-54
DOI 10.1016/j.ajog.2004.07.038, PubMed 15672002
TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
BMC Cancer, 5, 134
DOI 10.1186/1471-2407-5-134, PubMed 16229746
Publications 2004
No differences in p53 mutation frequencies between BRCA1-associated and sporadic ovarian cancers
Gynecol Oncol, 95 (3), 430-6
DOI 10.1016/j.ygyno.2004.08.035, PubMed 15581943
BRCA1 mutations in ovarian cancer and borderline tumours in Norway: a nested case-control study
Br J Cancer, 91 (10), 1829-34
DOI 10.1038/sj.bjc.6602199, PubMed 15477862
Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
Anal Chem, 76 (15), 4406-9
DOI 10.1021/ac049788k, PubMed 15283579
Publications 2001
Hereditary ovarian cancer in Norway
Unit of Medical Genetics and Department of Gynecologic Oncology, The Norwegian Radium Hospital, Oslo, 1 b. (flere pag.)
BIBSYS 010513000, ISBN 82-7722-132-0
Publications 2000
[Screening for ovarian cancer]
Tidsskr Nor Laegeforen, 120 (12), 1444-8
PubMed 10851943
Publications 1999
BRCA1 1675delA and 1135insA account for one third of Norwegian familial breast-ovarian cancer and are associated with later disease onset than less frequent mutations
Dis Markers, 15 (1-3), 79-84
DOI 10.1155/1999/278269, PubMed 10595257
Penetrances of BRCA1 1675delA and 1135insA with respect to breast cancer and ovarian cancer
Am J Hum Genet, 65 (3), 671-9
DOI 10.1086/302530, PubMed 10441573
Prospectively detected cancer in familial breast/ovarian cancer screening
Acta Obstet Gynecol Scand, 78 (10), 906-11
DOI 10.1034/j.1600-0412.1999.781013.x, PubMed 10577622
Three per cent of Norwegian ovarian cancers are caused by BRCA1 1675delA or 1135insA
Eur J Cancer, 35 (5), 779-81
DOI 10.1016/s0959-8049(99)00050-7, PubMed 10505039
[Hereditary breast cancer in Norway]
Tidsskr Nor Laegeforen, 119 (26), 3929-32
PubMed 10592755
Publications 1998
Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening
Hum Mutat, 11 (2), 166-74
DOI 10.1002/(SICI)1098-1004(1998)11:2<166::AID-HUMU10>3.0.CO;2-X, PubMed 9482581
Clinical implications of BRCA1 genetic testing
Acta Obstet Gynecol Scand, 77 (4), 458-61
PubMed 9598958
Prospective findings in breast cancer kindreds: annual incidence rates according to age, stage at diagnosis, mean sojourn time, and incidence rates for contralateral cancer
Breast, 7 (1), 55-59
DOI 10.1016/S0960-9776(98)90053-4
Oral contraceptives and the risk of hereditary ovarian cancer. Hereditary Ovarian Cancer Clinical Study Group
N Engl J Med, 339 (7), 424-8
DOI 10.1056/NEJM199808133390702, PubMed 9700175
Therapy effect of either paclitaxel or cyclophosphamide combination treatment in patients with epithelial ovarian cancer and relation to TP53 gene status
Br J Cancer, 78 (3), 375-81
DOI 10.1038/bjc.1998.502, PubMed 9703286
Publications 1997
The problem of skipped generation and subclinical disease in familial breast-ovarian cancer
Acta Obstet Gynecol Scand, 76 (2), 166-8
DOI 10.3109/00016349709050074, PubMed 9049291
A BRCA1 founder mutation, identified with haplotype analysis, allowing genotype/phenotype determination and predictive testing
Eur J Cancer, 33 (14), 2390-2
DOI 10.1016/s0959-8049(97)00328-6, PubMed 9616287
Publications 1996
Early detection of familial ovarian cancer
Eur J Cancer, 32A (10), 1645-51
DOI 10.1016/0959-8049(96)00137-2, PubMed 8983269
Inherited breast carcinoma--prospective findings in 1,194 women at risk
Acta Oncol, 35 Suppl 8, 7-11
DOI 10.3109/02841869609098515, PubMed 9073043
Inherited predisposition to breast carcinoma. Results of first round examination of 537 women at risk
Anticancer Res, 16 (4A), 1989-92
PubMed 8712731
Publications 1994
A randomised study of cisplatin versus thiotepa as induction chemotherapy in advanced ovarian carcinoma
Eur J Cancer, 30A (10), 1470-4
DOI 10.1016/0959-8049(94)00240-6, PubMed 7833104
Publications 1993
Evaluation of endometrial thickness measured by endovaginal ultrasound in women with postmenopausal bleeding
Acta Obstet Gynecol Scand, 72 (2), 116-9
DOI 10.3109/00016349309023423, PubMed 8383406
EVALUATION OF ENDOMETRIUM WITH TRANSVAGINAL ULTRASOUND - REPLY
Acta Obstet. Gynecol. Scand., 72 (8), 687
DOI 10.3109/00016349309021170
Publications 1991
Monochorionic monoamniotic twins--the most precarious of twin pregnancies
Acta Obstet Gynecol Scand, 70 (4-5), 381-3
DOI 10.3109/00016349109007895, PubMed 1746268