Elisabeth Schrumpf

  • Senior dermatologist; MD, PhD

Education

MD University of Oslo, 2011

Positions

2023 -  :  Senior dermatologist & researcher

2017 - 2022 : Resident dermatologist

2012 - 2017: PhD Research Fellow, NoPSC, OUH Rikshospitalet

2011 - 2012: Internship in Medicine, Surgery and General Practice, Sandnessjøen/ Dønna

Research interests

Immunology, microbiota, psoriasis, hidradenitis suppurativa, skin inflammation, skin cancer.

 

Unconventional T cells in skin inflammation

Unconventional T-lymphocytes are immune cells largely localized at barrier sites such as mucosal surfaces and in the skin. They have qualities of both innate and adaptive immune cells serving as a bridge between these compartments of the immune system. We aim to investigate their role in skin inflammation, with hidradenitis suppurativa as a model disease.

Project leader: Elisabeth Schrumpf. Others: Olav Sundnes, Jan C. Sitek, Olaf Antonsen. Collaborators: Institute of Internal Medicine OUH, Harvard Medical School, University Paris Descartes, Maynooth University.

 

Publications 2020

Louwe MC, Olsen MB, Kaasboll OJ, Yang K, Fosshaug LE, Alfsnes K, Ogaard JDS, Rashidi A, Skulberg VM, Yang MY, Fonseca DD, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjoras M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC-Basic Transl. Sci., 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013

Publications 2018

Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2018)
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
Am. J. Physiol.-Gastroint. Liver Physiol., 314 (3), G349-G359
DOI 10.1152/ajpgi.00124.2017

Schrumpf E, Rizvi SMH (2018)
Pustular drug rash
Tidsskr. Nor. Laegeforen., 138 (18), 1746

Publications 2017

Schrumpf E, Jiang XJ, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
PHYSIOL. REP., 5 (4), e13117
DOI 10.14814/phy2.13117

Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Backhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2017)
The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
J. Hepatol., 66 (2), 382-389
DOI 10.1016/j.jhep.2016.09.020

Publications 2015

Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WTH, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L (2015)
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
Nat. Biotechnol., 33 (8), 845-+
DOI 10.1038/nbt.3275

Schrumpf E, Tan C, Karlsen TH, Sponheim J, Bjorkstrom NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E (2015)
The biliary epithelium presents antigens to and activates natural killer T cells
Hepatology, 62 (4), 1249-1259
DOI 10.1002/hep.27840

Scroll to top