Elisabeth Schrumpf

  • Senior dermatologist; MD, PhD

Education

MD University of Oslo, 2011

Positions

2023 -  :  Senior dermatologist & researcher

2017 - 2022 : Resident dermatologist

2012 - 2017: PhD Research Fellow, NoPSC, OUH Rikshospitalet

2011 - 2012: Internship in Medicine, Surgery and General Practice, Sandnessjøen/ Dønna

Research interests

Immunology, microbiota, psoriasis, hidradenitis suppurativa, skin inflammation, skin cancer.

 

Unconventional T cells in skin inflammation

Unconventional T-lymphocytes are immune cells largely localized at barrier sites such as mucosal surfaces and in the skin. They have qualities of both innate and adaptive immune cells serving as a bridge between these compartments of the immune system. We aim to investigate their role in skin inflammation, with hidradenitis suppurativa as a model disease.

Project leader: Elisabeth Schrumpf. Others: Olav Sundnes, Jan C. Sitek, Olaf Antonsen. Collaborators: Institute of Internal Medicine OUH, Harvard Medical School, University Paris Descartes, Maynooth University.

 

Publications 2024

Oldereid TS, Jiang X, Øgaard J, Schrumpf E, Bjørnholt JV, Rasmussen H, Melum E (2024)
Microbial exposure during early life regulates development of bile duct inflammation
Scand J Gastroenterol, 59 (2), 192-201
DOI 10.1080/00365521.2023.2278423, PubMed 37997753

Publications 2023

Kreyberg I, Schrumpf E, Fredrik von Krogh C, Lilleng R, Tjønnfjord GE (2023)
Successful treatment of subcorneal pustular dermatosis targeting an underlying monoclonal IgA gammopathy
JAAD Case Rep, 41, 33-36
DOI 10.1016/j.jdcr.2023.08.036, PubMed 37842157

Publications 2022

Gallagher C, Mahon JM, O'Neill C, Cassidy FC, Dunbar H, De Barra C, Cadden C, Pisarska MM, Wood NAW, Masterson JC, McNamee EN, Schrumpf E, English K, O'Shea D, Tobin AM, Hogan AE (2022)
Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu
J Invest Dermatol, 143 (6), 1094-1097.e2
DOI 10.1016/j.jid.2022.11.011, PubMed 36516909

Publications 2020

Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377

Publications 2018

Schrumpf E, Rizvi SMH (2018)
[Pustular drug eruption]
Tidsskr Nor Laegeforen, 138 (18)
DOI 10.4045/tidsskr.18.0333, PubMed 30421738

Schrumpf E, Rizvi SMH (2018)
Pustular drug rash
Tidsskr. Nor. Laegeforen., 138 (18), 1746

Publications 2017

Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
DOI 10.1152/ajpgi.00124.2017, PubMed 29212771

Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
Physiol Rep, 5 (4)
DOI 10.14814/phy2.13117, PubMed 28219981

Publications 2016

Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2016)
The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
J Hepatol, 66 (2), 382-389
DOI 10.1016/j.jhep.2016.09.020, PubMed 27720803

Publications 2015

Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WT, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L (2015)
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
Nat Biotechnol, 33 (8), 845-852
DOI 10.1038/nbt.3275, PubMed 26167629

Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E (2015)
The biliary epithelium presents antigens to and activates natural killer T cells
Hepatology, 62 (4), 1249-59
DOI 10.1002/hep.27840, PubMed 25855031

Publications 2009

Michalsen S, Schrumpf E, Beiske K, Tierens A, Stenberg V, Tjønnfjord GE (2009)
[Large granular lymphocytic leukaemia]
Tidsskr Nor Laegeforen, 129 (11), 1098-102
DOI 10.4045/tidsskr.09.0152, PubMed 19488091

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