Bjørn Dalhus

  • Research scientist; PhD
  • +47 230 70 908
 

Publications 2023

Misceo D, Lirussi L, Strømme P, Sumathipala D, Guerin A, Wolf NI, Server A, Stensland M, Dalhus B, Tolun A, Kroes HY, Nyman TA, Nilsen HL, Frengen E (2023)
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474

Publications 2022

Frick R, Høydahl LS, Hodnebrug I, Vik ES, Dalhus B, Sollid LM, Gray JJ, Sandlie I, Løset GÅ (2022)
Affinity maturation of TCR-like antibodies using phage display guided by structural modeling
Protein Eng Des Sel, 35
DOI 10.1093/protein/gzac005, PubMed 35871543

Li M, Klungland A, Dalhus B (2022)
Studies on Protein-RNA:DNA Hybrid Interactions by Microscale Thermophoresis (MST)
Methods Mol Biol, 2528, 239-251
DOI 10.1007/978-1-0716-2477-7_15, PubMed 35704195

Publications 2021

Ahmadi A, Till K, Backe PH, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Rowe AD, Dalhus B (2021)
Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex
Commun Biol, 4 (1), 876
DOI 10.1038/s42003-021-02400-x, PubMed 34267321

Blindheim FH, Malme AT, Dalhus B, Sundby E, Hoff BH (2021)
Synthesis and Evaluation of Fused Pyrimidines as E. coli Thymidylate Monophosphate Kinase Inhibitors
ChemistrySelect, 6 (45), 12852-12857
DOI 10.1002/slct.202103796

Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2021)
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ Res, 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703

Smith V, Nilssen IKB, Hegna IK, Dalhus B, Fagerlund A, Økstad OA (2021)
CdgL is a degenerate nucleotide cyclase domain protein affecting flagellin synthesis and motility in Bacillus thuringiensis
Res Microbiol, 172 (4-5), 103850
DOI 10.1016/j.resmic.2021.103850, PubMed 34082027

Publications 2020

Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390

Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT (2020)
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
Sci Transl Med, 12 (565)
DOI 10.1126/scitranslmed.abb0580, PubMed 33055243

Nedal A, Ræder SB, Dalhus B, Helgesen E, Forstrøm RJ, Lindland K, Sumabe BK, Martinsen JH, Kragelund BB, Skarstad K, Bjørås M, Otterlei M (2020)
Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis
Nucleic Acids Res, 48 (10), 5540-5554
DOI 10.1093/nar/gkaa278, PubMed 32347931

Nilsen J, Trabjerg E, Grevys A, Azevedo C, Brennan SO, Stensland M, Wilson J, Sand KMK, Bern M, Dalhus B, Roopenian DC, Sandlie I, Rand KD, Andersen JT (2020)
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072

Naas AE, MacKenzie AK, Dalhus B, Eijsink VGH, Pope PB (2020)
Author Correction: Structural Features of a Bacteroidetes-Affiliated Cellulase Linked with a Polysaccharide Utilization Locus
Sci Rep, 10 (1), 6287
DOI 10.1038/s41598-020-62786-2, PubMed 32269252

Publications 2019

Abakir A, Giles TC, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Li M, Eleftheriou M, Crutchley J, Flatt L, Young L, Gaffney DJ, Denning C, Dalhus B, Emes RD, Gackowski D, Corrêa IR, Garcia-Perez JL, Klungland A, Gromak N, Ruzov A (2019)
N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
Nat Genet, 52 (1), 48-55
DOI 10.1038/s41588-019-0549-x, PubMed 31844323

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2019)
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 10 (1), 1991
DOI 10.1038/s41467-019-10070-x, PubMed 31024006

Ahmadi A, Till K, Hafting Y, Schüttpelz M, Bjørås M, Glette K, Tørresen J, Rowe AD, Dalhus B (2019)
Additive manufacturing of laminar flow cells for single-molecule experiments
Sci Rep, 9 (1), 16784
DOI 10.1038/s41598-019-53151-z, PubMed 31727950

Madhuprakash J, Dalhus B, Vaaje-Kolstad G, Sakuda S, Podile AR, Eijsink VGH, Sørlie M (2019)
Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans
J Phys Chem B, 123 (10), 2270-2279
DOI 10.1021/acs.jpcb.8b11448, PubMed 30789732

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765

Publications 2018

Ahmadi A, Rosnes I, Blicher P, Diekmann R, Schüttpelz M, Glette K, Tørresen J, Bjørås M, Dalhus B, Rowe AD (2018)
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V
Nat Commun, 9 (1), 5381
DOI 10.1038/s41467-018-07797-4, PubMed 30568191

Grimholt RM, Vestli A, Urdal P, Bechensteen AG, Fjeld B, Dalhus B, Klingenberg O (2018)
Hb Oslo [β42(CD1)Phe→Ile; HBB: c.127T>A]: A Novel Unstable Hemoglobin Variant Found in a Norwegian Patient
Hemoglobin, 42 (2), 78-83
DOI 10.1080/03630269.2018.1468773, PubMed 30032685

Madhuprakash J, Dalhus B, Rani TS, Podile AR, Eijsink VGH, Sørlie M (2018)
Key Residues Affecting Transglycosylation Activity in Family 18 Chitinases: Insights into Donor and Acceptor Subsites
Biochemistry, 57 (29), 4325-4337
DOI 10.1021/acs.biochem.8b00381, PubMed 29939724

Nilsen J, Bern M, Sand KMK, Grevys A, Dalhus B, Sandlie I, Andersen JT (2018)
Human and mouse albumin bind their respective neonatal Fc receptors differently
Sci Rep, 8 (1), 14648
DOI 10.1038/s41598-018-32817-0, PubMed 30279529

Publications 2017

Forsberg Z, Bissaro B, Gullesen J, Dalhus B, Vaaje-Kolstad G, Eijsink VGH (2017)
Structural determinants of bacterial lytic polysaccharide monooxygenase functionality
J Biol Chem, 293 (4), 1397-1412
DOI 10.1074/jbc.M117.817130, PubMed 29222333

Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ (2017)
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121

Lång A, Eriksson J, Schink KO, Lång E, Blicher P, Połeć A, Brech A, Dalhus B, Bøe SO (2017)
Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Nucleus, 8 (4), 404-420
DOI 10.1080/19491034.2017.1306161, PubMed 28402725

Publications 2016

Forsberg Z, Nelson CE, Dalhus B, Mekasha S, Loose JS, Crouch LI, Røhr ÅK, Gardner JG, Eijsink VG, Vaaje-Kolstad G (2016)
Structural and Functional Analysis of a Lytic Polysaccharide Monooxygenase Important for Efficient Utilization of Chitin in Cellvibrio japonicus
J Biol Chem, 291 (14), 7300-12
DOI 10.1074/jbc.M115.700161, PubMed 26858252

Foss S, Watkinson RE, Grevys A, McAdam MB, Bern M, Høydahl LS, Dalhus B, Michaelsen TE, Sandlie I, James LC, Andersen JT (2016)
TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
J Immunol, 196 (8), 3452-3459
DOI 10.4049/jimmunol.1502601, PubMed 26962230

Nawaz MS, Vik ES, Berges N, Fladeby C, Bjørås M, Dalhus B, Alseth I (2016)
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
J Biol Chem, 291 (41), 21786-21801
DOI 10.1074/jbc.M116.730911, PubMed 27573237

Nawaz MS, Vik ES, Ronander ME, Solvoll AM, Blicher P, Bjørås M, Alseth I, Dalhus B (2016)
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease
Sci Rep, 6, 24979
DOI 10.1038/srep24979, PubMed 27108838

Qu Y, Gharbi N, Yuan X, Olsen JR, Blicher P, Dalhus B, Brokstad KA, Lin B, Øyan AM, Zhang W, Kalland KH, Ke X (2016)
Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer
Proc Natl Acad Sci U S A, 113 (33), 9339-44
DOI 10.1073/pnas.1604520113, PubMed 27482107

Publications 2015

Dalhus B, Alseth I, Bjørås M (2015)
Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V
Prog Biophys Mol Biol, 117 (2-3), 134-142
DOI 10.1016/j.pbiomolbio.2015.03.005, PubMed 25824682

Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2015)
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
J Biol Chem, 291 (9), 4561-79
DOI 10.1074/jbc.M115.677898, PubMed 26668322

Heimdal K, Dalhus B, Rødningen OK, Kroken M, Eiklid K, Dheyauldeen S, Røysland T, Andersen R, Kulseth MA (2015)
Mutation analysis in Norwegian families with hereditary hemorrhagic telangiectasia: founder mutations in ACVRL1
Clin Genet, 89 (2), 182-6
DOI 10.1111/cge.12612, PubMed 25970827

Mahajan TR, Ytre-Arne ME, Strøm-Andersen P, Dalhus B, Gundersen LL (2015)
Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1
Molecules, 20 (9), 15944-65
DOI 10.3390/molecules200915944, PubMed 26364627

Mekasha S, Forsberg Z, Dalhus B, Bacik JP, Choudhary S, Schmidt-Dannert C, Vaaje-Kolstad G, Eijsink VG (2015)
Structural and functional characterization of a small chitin-active lytic polysaccharide monooxygenase domain of a multi-modular chitinase from Jonesia denitrificans
FEBS Lett, 590 (1), 34-42
DOI 10.1002/1873-3468.12025, PubMed 26763108

Naas AE, MacKenzie AK, Dalhus B, Eijsink VGH, Pope PB (2015)
Structural Features of a Bacteroidetes-Affiliated Cellulase Linked with a Polysaccharide Utilization Locus
Sci Rep, 5, 11666
DOI 10.1038/srep11666, PubMed 26133573

Publications 2014

Alseth I, Dalhus B, Bjørås M (2014)
Inosine in DNA and RNA
Curr Opin Genet Dev, 26, 116-23
DOI 10.1016/j.gde.2014.07.008, PubMed 25173738

Andersen JT, Dalhus B, Viuff D, Ravn BT, Gunnarsen KS, Plumridge A, Bunting K, Antunes F, Williamson R, Athwal S, Allan E, Evans L, Bjørås M, Kjærulff S, Sleep D, Sandlie I, Cameron J (2014)
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding
J Biol Chem, 289 (19), 13492-502
DOI 10.1074/jbc.M114.549832, PubMed 24652290

Maier L, Hylse O, Necas M, Trbusek M, Ytre-Arne M, Dalhus B, Bjoras M, Paruch K (2014)
New carbocyclic nucleosides: synthesis of carbocyclic pseudoisocytidine and its analogs
Tetrahedron Lett., 55 (27), 3713-3716
DOI 10.1016/j.tetlet.2014.05.030

Misceo D, Holmgren A, Louch WE, Holme PA, Mizobuchi M, Morales RJ, De Paula AM, Stray-Pedersen A, Lyle R, Dalhus B, Christensen G, Stormorken H, Tjønnfjord GE, Frengen E (2014)
A dominant STIM1 mutation causes Stormorken syndrome
Hum Mutat, 35 (5), 556-64
DOI 10.1002/humu.22544, PubMed 24619930

Sand KM, Bern M, Nilsen J, Dalhus B, Gunnarsen KS, Cameron J, Grevys A, Bunting K, Sandlie I, Andersen JT (2014)
Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn)
J Biol Chem, 289 (50), 34583-94
DOI 10.1074/jbc.M114.587675, PubMed 25344603

Sand KM, Dalhus B, Christianson GJ, Bern M, Foss S, Cameron J, Sleep D, Bjørås M, Roopenian DC, Sandlie I, Andersen JT (2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies
J Biol Chem, 289 (24), 17228-39
DOI 10.1074/jbc.M113.522565, PubMed 24764301

Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
DOI 10.1074/jbc.M114.602581, PubMed 25336645

Publications 2013

Backe PH, Simm R, Laerdahl JK, Dalhus B, Fagerlund A, Okstad OA, Rognes T, Alseth I, Kolstø AB, Bjørås M (2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol, 183 (1), 66-75
DOI 10.1016/j.jsb.2013.04.007, PubMed 23623903

Krokeide SZ, Laerdahl JK, Salah M, Luna L, Cederkvist FH, Fleming AM, Burrows CJ, Dalhus B, Bjørås M (2013)
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin
DNA Repair (Amst), 12 (12), 1159-64
DOI 10.1016/j.dnarep.2013.04.026, PubMed 23755964

Rosnes I, Rowe AD, Vik ES, Forstrøm RJ, Alseth I, Bjørås M, Dalhus B (2013)
Structural basis of DNA loop recognition by endonuclease V
Structure, 21 (2), 257-65
DOI 10.1016/j.str.2012.12.007, PubMed 23313664

Simonelli V, Camerini S, Mazzei F, Van Loon B, Allione A, D'Errico M, Barone F, Minoprio A, Ricceri F, Guarrera S, Russo A, Dalhus B, Crescenzi M, Hübscher U, Bjørås M, Matullo G, Dogliotti E (2013)
Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies
Free Radic Biol Med, 63, 401-9
DOI 10.1016/j.freeradbiomed.2013.05.031, PubMed 23726996

Vik ES, Nawaz MS, Strøm Andersen P, Fladeby C, Bjørås M, Dalhus B, Alseth I (2013)
Endonuclease V cleaves at inosines in RNA
Nat Commun, 4, 2271
DOI 10.1038/ncomms3271, PubMed 23912683

Weel-Sneve R, Kristiansen KI, Odsbu I, Dalhus B, Booth J, Rognes T, Skarstad K, Bjørås M (2013)
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
DOI 10.1371/journal.pgen.1003260, PubMed 23408903

Publications 2012

Andersen JT, Dalhus B, Cameron J, Daba MB, Plumridge A, Evans L, Brennan SO, Gunnarsen KS, Bjørås M, Sleep D, Sandlie I (2012)
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
Nat Commun, 3, 610
DOI 10.1038/ncomms1607, PubMed 22215085

Dalhus B, Nilsen L, Korvald H, Huffman J, Forstrøm RJ, McMurray CT, Alseth I, Tainer JA, Bjørås M (2012)
Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2
Structure, 21 (1), 154-166
DOI 10.1016/j.str.2012.11.004, PubMed 23245849

Fladeby C, Vik ES, Laerdahl JK, Gran Neurauter C, Heggelund JE, Thorgaard E, Strøm-Andersen P, Bjørås M, Dalhus B, Alseth I (2012)
The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures
PLoS One, 7 (11), e47466
DOI 10.1371/journal.pone.0047466, PubMed 23139746

Jobert L, Skjeldam HK, Dalhus B, Galashevskaya A, Vågbø CB, Bjørås M, Nilsen H (2012)
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control
Mol Cell, 49 (2), 339-45
DOI 10.1016/j.molcel.2012.11.010, PubMed 23246433

Payne CM, Baban J, Horn SJ, Backe PH, Arvai AS, Dalhus B, Bjørås M, Eijsink VG, Sørlie M, Beckham GT, Vaaje-Kolstad G (2012)
Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases
J Biol Chem, 287 (43), 36322-30
DOI 10.1074/jbc.M112.402149, PubMed 22952223

Vik ES, Alseth I, Forsbring M, Helle IH, Morland I, Luna L, Bjørås M, Dalhus B (2012)
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities
DNA Repair (Amst), 11 (9), 766-73
DOI 10.1016/j.dnarep.2012.07.002, PubMed 22858590

Publications 2011

Belova NV, Dalhus B, Girichev GV, Giricheva NI, Haaland A, Kuzmima NP, Zhukova TA (2011)
The molecular structure of tris-2,2,6,6-tetramethyl-heptane-3,5-dione aluminium: gas-phase electron diffraction, quantum chemical calculations and X-ray crystallography
Struct. Chem., 22 (2), 393-399
DOI 10.1007/s11224-010-9729-0

Dalhus B, Forsbring M, Helle IH, Vik ES, Forstrøm RJ, Backe PH, Alseth I, Bjørås M (2011)
Separation-of-function mutants unravel the dual-reaction mode of human 8-oxoguanine DNA glycosylase
Structure, 19 (1), 117-27
DOI 10.1016/j.str.2010.09.023, PubMed 21220122

Lauritzen KH, Dalhus B, Storm JF, Bjørås M, Klungland A (2011)
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
Mech Ageing Dev, 132 (8-9), 424-8
DOI 10.1016/j.mad.2011.02.006, PubMed 21354441

Vaaje-Kolstad G, Bøhle LA, Gåseidnes S, Dalhus B, Bjørås M, Mathiesen G, Eijsink VG (2011)
Characterization of the chitinolytic machinery of Enterococcus faecalis V583 and high-resolution structure of its oxidative CBM33 enzyme
J Mol Biol, 416 (2), 239-54
DOI 10.1016/j.jmb.2011.12.033, PubMed 22210154

Yang M, Aamodt RM, Dalhus B, Balasingham S, Helle I, Andersen P, Tønjum T, Alseth I, Rognes T, Bjørås M (2011)
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
DNA Repair (Amst), 10 (6), 595-602
DOI 10.1016/j.dnarep.2011.03.007, PubMed 21570366

Publications 2010

Görbitz CH, Dalhus B, Day GM (2010)
Pseudoracemic amino acid complexes: blind predictions for flexible two-component crystals
Phys Chem Chem Phys, 12 (30), 8466-77
DOI 10.1039/c004055j, PubMed 20461256

Johnsen L, Flåtten I, Morigen, Dalhus B, Bjørås M, Waldminghaus T, Skarstad K (2010)
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Mol Microbiol, 79 (2), 433-46
DOI 10.1111/j.1365-2958.2010.07453.x, PubMed 21219462

Publications 2009

Dalhus B, Arvai AS, Rosnes I, Olsen ØE, Backe PH, Alseth I, Gao H, Cao W, Tainer JA, Bjørås M (2009)
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair
Nat Struct Mol Biol, 16 (2), 138-43
DOI 10.1038/nsmb.1538, PubMed 19136958

Dalhus B, Laerdahl JK, Backe PH, Bjørås M (2009)
DNA base repair--recognition and initiation of catalysis
FEMS Microbiol Rev, 33 (6), 1044-78
DOI 10.1111/j.1574-6976.2009.00188.x, PubMed 19659577

Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjørås M, Boberg KM, Alseth I (2009)
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Carcinogenesis, 30 (7), 1147-54
DOI 10.1093/carcin/bgp118, PubMed 19443904

Hol J, Küchler AM, Johansen FE, Dalhus B, Haraldsen G, Oynebråten I (2009)
Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodies
J Biol Chem, 284 (35), 23532-9
DOI 10.1074/jbc.M900874200, PubMed 19578117

Publications 2007

Dalhus B, Helle IH, Backe PH, Alseth I, Rognes T, Bjørås M, Laerdahl JK (2007)
Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
Nucleic Acids Res, 35 (7), 2451-9
DOI 10.1093/nar/gkm039, PubMed 17395642

Publications 2006

Hoell IA, Dalhus B, Heggset EB, Aspmo SI, Eijsink VG (2006)
Crystal structure and enzymatic properties of a bacterial family 19 chitinase reveal differences from plant enzymes
FEBS J, 273 (21), 4889-900
DOI 10.1111/j.1742-4658.2006.05487.x, PubMed 17010167

Lersch M, Dalhus B, Bercaw JE, Labinger J, Tilset M (2006)
Improved one-pot synthesis of mixed methyl-aryl platinum(II) diimine complexes
Organometallics, 25 (4), 1055-1058
DOI 10.1021/om050899z

Publications 2005

Fimland G, Johnsen L, Dalhus B, Nissen-Meyer J (2005)
Pediocin-like antimicrobial peptides (class IIa bacteriocins) and their immunity proteins: biosynthesis, structure, and mode of action
J Pept Sci, 11 (11), 688-96
DOI 10.1002/psc.699, PubMed 16059970

Johnsen L, Dalhus B, Leiros I, Nissen-Meyer J (2005)
1.6-Angstroms crystal structure of EntA-im. A bacterial immunity protein conferring immunity to the antimicrobial activity of the pediocin-like bacteriocin enterocin A
J Biol Chem, 280 (19), 19045-50
DOI 10.1074/jbc.M501386200, PubMed 15753083

Publications 2004

Bjørk A, Dalhus B, Mantzilas D, Sirevåg R, Eijsink VG (2004)
Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface
J Mol Biol, 341 (5), 1215-26
DOI 10.1016/j.jmb.2004.06.079, PubMed 15321717

Dalhus B, Gorbitz CH (2004)
Crystal structures of hydrophobic amino acids: interaction energies of hydrogen-bonded layers revealed by ab initio calculations
Theochem-J. Mol. Struct., 675 (1-3), 47-52
DOI 10.1016/j.theochem.2003.12.032

Fooladi E, Dalhus B, Tilset M (2004)
Synthesis and characterization of half-sandwich N-heterocyclic carbene complexes of cobalt and rhodium
Dalton Trans (22), 3909-17
DOI 10.1039/b408750j, PubMed 15540136

Helle IH, Løkken CV, Görbitz CH, Dalhus B (2004)
L-Seryl-L-phenylalanine
Acta Crystallogr C, 60 (Pt 10), o771-2
DOI 10.1107/S0108270104021523, PubMed 15467155

Moen A, Frøseth M, Görbitz CH, Dalhus B (2004)
A non-planar peptide bond in L-seryl-L-valine
Acta Crystallogr C, 60 (Pt 8), o564-5
DOI 10.1107/S0108270104014325, PubMed 15295188

Netland KA, Andresen K, Gorbitz CH, Dalhus B (2004)
L-alanyl-L-threonine
Acta Crystallogr. Sect. E.-Crystallogr. Commun., 60, O951-O953
DOI 10.1107/S1600536804010578

Publications 2003

Bjørk A, Dalhus B, Mantzilas D, Eijsink VG, Sirevåg R (2003)
Stabilization of a tetrameric malate dehydrogenase by introduction of a disulfide bridge at the dimer-dimer interface
J Mol Biol, 334 (4), 811-21
DOI 10.1016/j.jmb.2003.10.006, PubMed 14636605

Dalhus B, Johnsen L, Nissen-Meyer J (2003)
Crystallization and preliminary X-ray data investigation of the bacterial enterocin A immunity protein at 1.65 A resolution
Acta Crystallogr D Biol Crystallogr, 59 (Pt 7), 1291-3
DOI 10.1107/s0907444903009879, PubMed 12832790

Sridhar B, Srinivasan N, Dalhus B, Rajaram RK (2003)
DL-valinium perchlorate
Acta Crystallogr. Sect. E.-Crystallogr. Commun., 59, O28-O30
DOI 10.1107/S1600536802022225

Publications 2002

Belyakov AV, Dalhus B, Haaland A, Shorokhov DJ, Volden HV (2002)
Molecular structure and conformational preferences of trimethylphosphite, P(OCH3)(3), as a free molecule and as a ligand in d-block metal complexes
J. Chem. Soc.-Dalton Trans. (19), 3756-3762
DOI 10.1039/b204777m

Dalhus B, Saarinen M, Sauer UH, Eklund P, Johansson K, Karlsson A, Ramaswamy S, Bjørk A, Synstad B, Naterstad K, Sirevåg R, Eklund H (2002)
Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases
J Mol Biol, 318 (3), 707-21
DOI 10.1016/S0022-2836(02)00050-5, PubMed 12054817

Fooladi E, Dalhus B, Rømming C, Tilset M (2002)
An organometallic RhIII complex with a distorted octahedral structure: (acetonitrile-kappaN)dimethyl(1,4,7-trimethyl-1,4,7-triazacyclononane-kappa3N,N',N")rhodium(III) tetraphenylborate
Acta Crystallogr C, 58 (Pt 12), m567-9
DOI 10.1107/s0108270102019182, PubMed 12466599

Fooladi E, Graham T, Turner ML, Dalhus B, Maitlis PM, Tilset M (2002)
Oxidatively induced M-C bond cleavage reactions of Cp*Ir(Me2SO)Me-2 and Cp*Rh(Me2SO)M-2 (Cp* = eta(5)-C5Me5)
J. Chem. Soc.-Dalton Trans. (6), 975-982
DOI 10.1039/b107451m

Sridhar B, Srinivasan N, Dalhus B, Rajaram RK (2002)
A triclinic polymorph of L-argininium chloride
Acta Crystallogr. Sect. E.-Crystallogr. Commun., 58, O747-O749
DOI 10.1107/S160053680201022X

Sridhar B, Srinivasan N, Dalhus B, Rajaram RK (2002)
L-Methionine L-methioninium perchlorate monohydrate
Acta Crystallogr. Sect. E.-Crystallogr. Commun., 58, O779-O781
DOI 10.1107/S1600536802010656

Sridhar B, Srinivasan N, Dalhus B, Rajaram RK (2002)
L-Citrullinium perchlorate
Acta Crystallogr. Sect. E.-Crystallogr. Commun., 58, O1177-O1179
DOI 10.1107/S160053680201766X

Publications 2001

Andresen G, Eriksen AB, Dalhus B, Gundersen LL, Rise F (2001)
Synthesis of 6-substituted purin-2-ones with potential cytokinin activity
J. Chem. Soc.-Perkin Trans. 1 (14), 1662-1672
DOI 10.1039/b101327k

Hersleth HP, Dalhus B, Görbitz CH, Andersson KK (2001)
An iron hydroxide moiety in the 1.35 A resolution structure of hydrogen peroxide derived myoglobin compound II at pH 5.2
J Biol Inorg Chem, 7 (3), 299-304
DOI 10.1007/s007750100296, PubMed 11935353

Publications 2000

Dalhus B (2000)
Crystal structures of hydrophobic amino acid complexes - a multivariate analysis of hydrogen bond geometries
In Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo, The Faculty, Oslo, no. 62, 1 b. (flere pag.)
BIBSYS 00107105x

Dalhus B, Gorbitz CH (2000)
Structural relationships in crystals accommodating different stereoisomers of 2-amino-3-methylpentanoic acid
Acta Crystallogr B, 56 (Pt 4), 720-7
DOI 10.1107/s0108768100002810, PubMed 10944265

Dalhus B, Görbitz CH (2000)
Non-centrosymmetric racemates: space-group frequencies and conformational similarities between crystallographically independent molecules
Acta Crystallogr B, 56 (Pt 4), 715-9
DOI 10.1107/s0108768100002172, PubMed 10944264

Ostby OB, Dalhus B, Gundersen LL, Rise F, Bast A, Haenen GRMM (2000)
Synthesis of 1-substituted 7-cyano-2,3-diphenylindolizines and evaluation of antioxidant properties
Eur. J. Org. Chem., 2000 (22), 3763-3770

Publications 1999

Dalhus B, Gorbitz CH (1999)
Molecular aggregation in selected crystalline 1 : 1 complexes of hydrophobic D- and L-amino acids. II. The D-norleucine series
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 55, 1105-1112
DOI 10.1107/S0108270199003649

Dalhus B, Gorbitz CH (1999)
Molecular aggregation in selected crystalline 1 : 1 complexes of hydrophohic D- and L-amino acids. III. The L-leucine and L-valine series
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 55, 1547-1555
DOI 10.1107/S0108270199006162

Dalhus B, Görbitz CH (1999)
Molecular aggregation in crystalline 1:1 complexes of hydrophobic D- and L-amino acids. I. The L-isoleucine series
Acta Crystallogr B, 55 (Pt 3), 424-431
DOI 10.1107/s0108768198013494, PubMed 10927385

Liu FS, Dalhus B, Gundersen LL, Rise F (1999)
Addition and cycloaddition to 2- and 8-vinylpurines
Acta Chem. Scand., 53 (4), 269-279
DOI 10.3891/acta.chem.scand.53-0269

Tusvik PH, Mostad A, Dalhus B, Rosenqvist E (1999)
A 1 : 1 complex between deoxycholate and tris(hydroxymethyl)methylammonium
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 55, 1113-1115
DOI 10.1107/S0108270199004370

Publications 1998

Loiten MS, Dalhus B, Fjaertoft B, Klaveness J (1998)
trans-2,3-Diiodo-2-butene-1,4-diol
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 54, 555-557
DOI 10.1107/S0108270197014406

Publications 1996

Dalhus B, Gorbitz CH (1996)
Crystal structures of hydrophobic amino acids .1. redeterminations of L-methionine and L-valine at 120 K
Acta Chem. Scand., 50 (6), 544-548
DOI 10.3891/acta.chem.scand.50-0544

Dalhus B, Gorbitz CH (1996)
Triclinic form of DL-valine
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 52, 1759-1761
DOI 10.1107/S0108270196002491

Dalhus B, Gorbitz CH (1996)
DL-norleucine, beta form at 120 K
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 52, 1761-1764
DOI 10.1107/S0108270196003642

Dalhus B, Görbitz CH (1996)
Glycyl-L-leucyl-L-tyrosine dihydrate 2-propanol solvate
Acta Crystallogr C, 52 ( Pt 8), 2087-90
DOI 10.1107/s0108270196002041, PubMed 8819306

Gorbitz CH, Dalhus B (1996)
L-isoleucine, redetermination at 120 K
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 52, 1464-1466
DOI 10.1107/S0108270195016386

Gorbitz CH, Dalhus B (1996)
Redetermination of L-leucine at 120 K
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 52, 1754-1756
DOI 10.1107/S0108270196002296

Gorbitz CH, Dalhus B (1996)
L-cysteine, monoclinic form, redetermination at 120 K
Acta Crystallogr. Sect. C-Cryst. Struct. Commun., 52, 1756-1759
DOI 10.1107/S0108270196003952

Publications 1995

Dalhus B (1995)
Røntgenkrystallografisk strukturbestemmelse av aminosyrene L-valin og L-metionin og tripeptidet L-glysyl-L-leusyl-L-tyrosin: studier av hydrogenbindingsnettverk i hydrofobe aminosyrestrukturer. Molekyldynamikksimulering av L-glysyl-L-leusyl-L-tyrosin
B. Dalhus, Oslo, 100 s.
BIBSYS 951357018