Publications 2021

Berg KCG, Brunsell TH, Sveen A, Alagaratnam S, Bjornslett M, Hektoen M, Brudvik KW, Rosok BI, Bjornbeth BA, Nesbakken A, Lothe RA (2021)
Genomic and prognostic heterogeneity among RAS/BRAF(V600E)/TP53 co-mutated resectable colorectal liver metastases
Mol. Oncol., 15 (4), 830-845
DOI 10.1002/1878-0261.12885

Bruun J, Eide PW, Bergsland CH, Bruck O, Svindland A, Arjama M, Valimaki K, Bjornslett M, Guren MG, Kallioniemi O, Nesbakken A, Lothe RA, Pellinen T (2021)
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Mol. Oncol.
DOI 10.1002/1878-0261.13159

Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Rosok BI, Bjornbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
npj Genom. Med., 6 (1), 59
DOI 10.1038/s41525-021-00223-7

Kleive D, Aas E, Angelsen JH, Bringeland EA, Nesbakken A, Nymo LS, Schultz JK, Soreide K, Yaqub S (2021)
Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps
Oncol. Ther., 9 (1), 111-120
DOI 10.1007/s40487-021-00148-2

Kryeziu K, Moosavi SH, Bergsland CH, Guren MG, Eide PW, Totland MZ, Lassen K, Abildgaard A, Nesbakken A, Sveen A, Lothe RA (2021)
Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
J. Transl. Med., 19 (1), 384
DOI 10.1186/s12967-021-03062-3

Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Rosok BI, Brudvik KW, Bjornbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med., 13 (1), 143
DOI 10.1186/s13073-021-00956-1

Slordahl KS, Klotz D, Olsen JA, Skovlund E, Undseth C, Abildgaard HL, Braendengen M, Nesbakken A, Larsen SG, Hanekamp BA, Holmboe L, Tvedt R, Sveen A, Lothe RA, Malinen E, Kaasa S, Guren MG (2021)
Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
Acta Oncol., 60 (7), 921-930
DOI 10.1080/0284186X.2021.1918763

Sveen A, Johannessen B, Eilertsen IA, Rosok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjornbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med., 13 (1), 142
DOI 10.1186/s13073-021-00955-2

Publications 2020

Bergsland CH, Bruun J, Guren MG, Svindland A, Bjornslett M, Smeby J, Hektoen M, Kolberg M, Domingo E, Pellinen T, Tomlinson I, Kerr D, Church DN, Nesbakken A, Sveen A, Lothe RA (2020)
Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
ESMO Open, 5 (6), e001040
DOI 10.1136/esmoopen-2020-001040

Brunsell TH, Sveen A, Bjornbeth BA, Rosok BI, Danielsen SA, Brudvik KW, Berg KCG, Johannessen B, Cengija V, Abildgaard A, Guren MG, Nesbakken A, Lothe RA (2020)
High Concordance and Negative Prognostic Impact of RAS/BRAF/PIK3CA Mutations in Multiple Resected Colorectal Liver Metastases
Clin. Colorectal Canc., 19 (1), E26-E47
DOI 10.1016/j.clcc.2019.09.003

Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Rosok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjornbeth BA, Sveen A, Lothe RA (2020)
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin. Cancer Res., 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637

Eilertsen IA, Moosavi SH, Stromme JM, Nesbakken A, Johannessen B, Lothe RA, Sveen A (2020)
Technical differences between sequencing and microarray platforms impact transcriptomic subtyping of colorectal cancer
Cancer Lett., 469, 246-255
DOI 10.1016/j.canlet.2019.10.040

Joranger P, Nesbakken A, Sorbye H, Hoff G, Oshaug A, Aas E (2020)
Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach
Eur. J. Health Econ., 21 (3), 321-334
DOI 10.1007/s10198-019-01130-6

Lopes N, Bergsland CH, Bjornslett M, Pellinen T, Svindland A, Nesbakken A, Almeida R, Lothe RA, David L, Bruun J (2020)
Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
Lab. Invest., 100 (1), 120-134
DOI 10.1038/s41374-019-0336-4

Montroni I, Rostoft S, Spinelli A, Van Leeuwen BL, Ercolani G, Saur NM, Jaklitsch MT, Somasundar PS, Carino ND, Ghignone F, Foca F, Zingaretti C, Audisio RA, Ugolini G, Garutti A, Taffurelli G, Zattoni D, Tramelli P, Sermonesi G, Di Candido F, Carvello M, Sacchi M, De Lucia F, Foppa C, Plas M et al. (2020)
GOSAFE - Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery: early analysis on 977 patients
J. Geriatr. Oncol., 11 (2), 244-255
DOI 10.1016/j.jgo.2019.06.017

Skrede OJ, De Raedt S, Kleppe A, Hveem TS, Liestol K, Maddison J, Askautrud HA, Pradhan M, Nesheim JA, Albregtsen F, Farstad IN, Domingo E, Church DN, Nesbakken A, Shepherd NA, Tomlinson I, Kerr R, Novelli M, Kerr DJ, Danielsen HE (2020)
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
Lancet, 395 (10221), 350-360

Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A (2020)
Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
EBioMedicine, 59, 102923
DOI 10.1016/j.ebiom.2020.102923

Publications 2019

Berg KCG, Sveen A, Holand M, Alagaratnam S, Berg M, Danielsen SA, Nesbakken A, Soreide K, Lothel RA (2019)
Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
Oncogene, 38 (33), 6109-6122
DOI 10.1038/s41388-019-0868-5

Brunsell TH, Cengija V, Sveen A, Bjornbeth BA, Rosok BI, Brudvik KW, Guren MG, Lothe RA, Abildgaard A, Nesbakken A (2019)
Heterogeneous radiological response to neoadjuvant therapy is associated with poor prognosis after resection of colorectal liver metastases
EJSO, 45 (12), 2340-2346
DOI 10.1016/j.ejso.2019.07.017

Dienstmann R, Villacampa G, Sveen A, Mason MJ, Niedzwiecki D, Nesbakken A, Moreno V, Warren RS, Lothe RA, Guinney J (2019)
Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer
Ann. Oncol., 30 (10), 1622-1629
DOI 10.1093/annonc/mdz287

Eilertsen IA, Sveen A, Stromme JM, Skotheim RI, Nesbakken A, Lothe RA (2019)
Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
Int. J. Cancer, 144 (4), 841-847
DOI 10.1002/ijc.31809

Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage
Br. J. Cancer, 121 (6), 474-482
DOI 10.1038/s41416-019-0540-4

Glaire MA, Domingo E, Sveen A, Bruun J, Nesbakken A, Nicholson G, Novelli M, Lawson K, Oukrif D, Kildal W, Danielsen HE, Kerr R, Kerr D, Tomlinson I, Lothe RA, Church DN (2019)
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage (vol 121, pg 474, 2019)
Br. J. Cancer, 121 (9), 807
DOI 10.1038/s41416-019-0590-7

Smeby J, Sveen A, Bergsland CH, Eilertsen IA, Danielsen SA, Eide PW, Hektoen M, Guren MG, Nesbakken A, Bruun J, Lothe RA (2019)
Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
ESMO Open, 4 (3), UNSP e000523
DOI 10.1136/esmoopen-2019-000523

Smeby J, Sveen A, Eilertsen IA, Danielsen SA, Hoff AM, Eide PW, Johannessen B, Hektoen M, Skotheim RI, Guren MG, Nesbakken A, Lothe RA (2019)
Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
Oncogenesis, 8, 35
DOI 10.1038/s41389-019-0141-3

Publications 2018

Bruun J, Sveen A, Barros R, Eide PW, Eilertsen I, Kolberg M, Pellinen T, David L, Svindland A, Kallioniemi O, Guren MG, Nesbakken A, Almeida R, Lothe RA (2018)
Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
Mol. Oncol., 12 (9), 1639-1655
DOI 10.1002/1878-0261.12347

Danielsen HE, Hveem TS, Domingo E, Pradhan M, Kleppe A, Syvertsen RA, Kostolomov I, Nesheim JA, Askautrud HA, Nesbakken A, Lothe RA, Svindland A, Shepherd N, Novelli M, Johnstone E, Tomlinson I, Kerr R, Kerr DJ (2018)
Prognostic markers for colorectal cancer: estimating ploidy and stroma
Ann. Oncol., 29 (3), 616-623
DOI 10.1093/annonc/mdx794

Gleditsch D, Wexels WA, Nesbakken A (2018)
Surgical options and trends in treating rectal prolapse: long-term results in a 19-year follow-up study
Langenbecks Arch. Surg., 403 (8), 991-998
DOI 10.1007/s00423-018-1728-4

Kleppe A, Albregtsen F, Vlatkovic L, Pradhan M, Nielsen B, Hveem TS, Askautrud HA, Kristensen GB, Nesbakken A, Trovik J, Waehre H, Tomlinson I, Shepherd NA, Novelli M, Kerr DJ, Danielsen HE (2018)
Chromatin organisation and cancer prognosis: a pan-cancer study
Lancet Oncol., 19 (3), 356-369
DOI 10.1016/S1470-2045(17)30899-9

Ommundsen N, Nesbakken A, Wyller TB, Skovlund E, Bakka AO, Jordhoy MS, Rostoft S (2018)
Post-discharge complications in frail older patients after surgery for colorectal cancer
EJSO, 44 (10), 1542-1547
DOI 10.1016/j.ejso.2018.06.024

Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhoy MS, Skovlund E, Rostoft S (2018)
Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial
Colorectal Dis., 20 (1), 16-25
DOI 10.1111/codi.13785

Ommundsen N, Wyller TB, Nesbakken A, Bakka AO, Jordhoy MS, Skovlund E, Rostoft S (2018)
Response to 'Preoperative geriatric assessment and tailored interventions in frail older patients with colorectal cancer: a randomized controlled trial' Reply
Colorectal Dis., 20 (4), 350-351
DOI 10.1111/codi.14059

Smeby J, Sveen A, Merok MA, Danielsen SA, Eilertsen A, Guren MG, Dienstmann R, Nesbakken A, Lothe RA (2018)
CMS-dependent prognostic impact of KRAS and BRAF(V600E) mutations in primary colorectal cancer
Ann. Oncol., 29 (5), 1227-1234
DOI 10.1093/annonc/mdy085

Sveen A, Bruun J, Eide PW, Eilertsen IA, Ramirez L, Murumagi A, Arjama M, Danielsen SA, Kryeziu K, Elez E, Tabernero J, Guinney J, Palmer HG, Nesbakken A, Kallioniemi O, Dienstmann R, Lothe RA (2018)
Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
Clin. Cancer Res., 24 (4), 794-806
DOI 10.1158/1078-0432.CCR-17-1234

Vedeld HM, Nesbakken A, Lothe RA, Lind GE (2018)
Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer
Clin. Epigenetics, 10, 70
DOI 10.1186/s13148-018-0503-2

Publications 2017

Dienstmann R, Mason MJ, Sinicrope FA, Phipps AI, Tejpar S, Nesbakken A, Danielsen SA, Sveen A, Buchanan DD, Clendenning M, Rosty C, Bot B, Alberts SR, Jessup JM, Lothe RA, Delorenzi M, Newcomb PA, Sargent D, Guinney J (2017)
Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study
Ann. Oncol., 28 (5), 1023-1031
DOI 10.1093/annonc/mdx052

Labori KJ, Guren MG, Brudvik KW, Rosok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjornbeth BA (2017)
Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival
Colorectal Dis., 19 (8), 731-738
DOI 10.1111/codi.13622

Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA (2017)
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Genome Med., 9, 46
DOI 10.1186/s13073-017-0434-0

Vedeld HM, Merok M, Jeanmougin M, Danielsen SA, Honne H, Presthus GK, Svindland A, Sjo OH, Hektoen M, Eknaes M, Nesbakken A, Lothe RA, Lind GE (2017)
CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers
Int. J. Cancer, 141 (5), 967-976
DOI 10.1002/ijc.30796

Publications 2016

Boye K, Jacob H, Frikstad KAM, Nesland JM, Maelandsmo GM, Dahl O, Nesbakken A, Flatmark K (2016)
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
Cancer Med., 5 (8), 1840-1849
DOI 10.1002/cam4.766

Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H, van Wezel T, Liefers GJ, Lothe RA, Danielsen SA, Sveen A, Nesbakken A, Zlobec I, Lugli A, Koelzer VH, Berger MD, Casteilvi-Bel S, Munoz J, de Bruyn M, Nijman HW, Novelli M et al. (2016)
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
Lancet Gastroenterol. Hepatol., 1 (3), 207-216
DOI 10.1016/S2468-1253(16)30014-0

Gleditsch D, Soreide OK, Nesbakken A (2016)
Managing Malignant Colorectal Obstruction with Self-Expanding Stents. A Closer Look at Bowel Perforations and Failed Procedures
J. Gastrointest. Surg., 20 (9), 1643-1649
DOI 10.1007/s11605-016-3186-z

Ronning B, Wyller TB, Nesbakken A, Skovlund E, Jordhoy MS, Bakka A, Rostoft S (2016)
Quality of life in older and frail patients after surgery for colorectal cancer-A follow-up study
J. Geriatr. Oncol., 7 (3), 195-200
DOI 10.1016/j.jgo.2016.03.002

Stornes T, Wibe A, Nesbakken A, Myklebust TA, Endreseth BH (2016)
National Early Rectal Cancer Treatment Revisited
Dis. Colon Rectum, 59 (7), 623-629
DOI 10.1097/DCR.0000000000000591

Publications 2015

Bruun J, Kolberg M, Ahlquist TC, Royrvik EC, Nome T, Leithe E, Lind GE, Merok MA, Rognum TO, Bjorkoy G, Johansen T, Lindblom A, Sun XF, Svindland A, Liestol K, Nesbakken A, Skotheim RI, Lothe RA (2015)
Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer
Clin. Cancer Res., 21 (16), 3759-3770
DOI 10.1158/1078-0432.CCR-14-3294

Danielsen SA, Eide PW, Nesbakken A, Guren T, Leithe E, Lothe RA (2015)
Portrait of the PI3K/AKT pathway in colorectal cancer
Biochim. Biophys. Acta-Rev. Cancer, 1855 (1), 104-121
DOI 10.1016/j.bbcan.2014.09.008

Guren MG, Korner H, Pfeffer F, Myklebust TA, Eriksen MT, Edna TH, Larsen SG, Knudsen KO, Nesbakken A, Wasmuth HH, Vonen B, Hofsli E, Faerden AE, Braendengen M, Dahl O, Steigen SE, Johansen MJ, Lindsetmo RO, Drolsum A, Tollali G, Dorum LM, Moller B, Wibe A (2015)
Nationwide improvement of rectal cancer treatment outcomes in Norway, 1993-2010
Acta Oncol., 54 (10), 1714-1722
DOI 10.3109/0284186X.2015.1034876

Joranger P, Nesbakken A, Hoff G, Sorbye H, Oshaug A, Aas E (2015)
Modeling and Validating the Cost and Clinical Pathway of Colorectal Cancer
Med. Decis. Mak., 35 (2), 255-265
DOI 10.1177/0272989X14544749

Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2015)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int. J. Cancer, 136 (4), 844-853
DOI 10.1002/ijc.29039

Publications 2014

Bruun J, Kolberg M, Nesland JM, Svindland A, Nesbakken A, Lothe RA (2014)
Prognostic significance of beta-catenin, E-cadherin, and SOX9 in colorectal cancer: results from a large populationp-representative series
Front. Oncol., 4, 118
DOI 10.3389/fonc.2014.00118

Hveem TS, Merok MA, Pretorius ME, Novelli M, Baevre MS, Sjo OH, Clinch N, Liestol K, Svindland A, Lothe RA, Nesbakken A, Danielsen HE (2014)
Prognostic impact of genomic instability in colorectal cancer
Br. J. Cancer, 110 (8), 2159-2164
DOI 10.1038/bjc.2014.133

Ingebrigtsen VA, Boye K, Nesland JM, Nesbakken A, Flatmark K, Fodstad O (2014)
B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome
BMC Cancer, 14, 602
DOI 10.1186/1471-2407-14-602

Lovf M, Nome T, Bruun J, Eknaes M, Bakken AC, Mpindi JP, Kilpinen S, Rognum TO, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2014)
A novel transcript, VNN1-AB, as a biomarker for colorectal cancer
Int. J. Cancer, 135 (9), 2077-2084
DOI 10.1002/ijc.28855

Nome T, Hoff AM, Bakken AC, Rognum TO, Nesbakken A, Skotheim RI (2014)
High Frequency of Fusion Transcripts Involving TCF7L2 in Colorectal Cancer: Novel Fusion Partner and Splice Variants
PLoS One, 9 (3), e91264
DOI 10.1371/journal.pone.0091264

Ommundsen N, Wyller TB, Nesbakken A, Jordhoy MS, Bakka A, Skovlund E, Rostoft S (2014)
Frailty Is an Independent Predictor of Survival in Older Patients With Colorectal Cancer
Oncologist, 19 (12), 1268-1275
DOI 10.1634/theoncologist.2014-0237

Ronning B, Wyller TB, Jordhoy MS, Nesbakken A, Bakka A, Seljeflot I, Kristjansson SR (2014)
Frailty indicators and functional status in older patients after colorectal cancer surgery
J. Geriatr. Oncol., 5 (1), 26-32
DOI 10.1016/j.jgo.2013.08.001

Sondenaa K, Quirke P, Hohenberger W, Sugihara K, Kobayashi H, Kessler H, Brown G, Tudyka V, D'Hoore A, Kennedy RH, West NP, Kim SH, Heald R, Storli KE, Nesbakken A, Moran B (2014)
The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery
Int. J. Colorectal Dis., 29 (4), 419-428
DOI 10.1007/s00384-013-1818-2

Publications 2013

Merok MA, Ahlquist T, Royrvik EC, Tufteland KF, Hektoen M, Sjo OH, Mala T, Svindland A, Lothe RA, Nesbakken A (2013)
Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
Ann. Oncol., 24 (5), 1274-1282
DOI 10.1093/annonc/mds614

Nedrebo BS, Soreide K, Nesbakken A, Eriksen MT, Soreide JA, Korner H, Norwegian Colorectal Canc Grp (2013)
Risk factors associated with poor lymph node harvest after colon cancer surgery in a national cohort
Colorectal Dis., 15 (6), E301-E308
DOI 10.1111/codi.12245

Sveen A, Nesbakken A, Agesen TH, Guren MG, Tveit KM, Skotheim RI, Lothe RA (2013)
Anticipating the Clinical Use of Prognostic Gene Expression-Based Tests for Colon Cancer Stage II and III: Is Godot Finally Arriving?
Clin. Cancer Res., 19 (24), 6669-6677
DOI 10.1158/1078-0432.CCR-13-1769

Publications 2012

Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA (2012)
ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
Gut, 61 (11), 1560-1567
DOI 10.1136/gutjnl-2011-301179

Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE (2012)
A Tissue-Based Comparative Effectiveness Analysis of Biomarkers for Early Detection of Colorectal Tumors
Clin. Transl. Gastroenterol., 3, e27
DOI 10.1038/ctg.2012.21

Cekaite L, Rantala JK, Bruun J, Guriby M, Agesen TH, Danielsen SA, Lind GE, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2012)
MiR-9,-31, and-182 Deregulation Promote Proliferation and Tumor Cell Survival in Colon Cancer
Neoplasia, 14 (9), 868-U126
DOI 10.1593/neo.121094

Kristjansson SR, Ronning B, Hurria A, Skovlund E, Jordhoy MS, Nesbakken A, Wyller TB (2012)
A comparison of two pre-operative frailty measures in older surgical cancer patients
J. Geriatr. Oncol., 3 (1), 1-7
DOI 10.1016/j.jgo.2011.09.002

Larssen L, Medhus AW, Korner H, Glomsaker T, Soberg T, Gleditsch D, Hovde O, Tholfsen JK, Skreden K, Nesbakken A, Hauge T (2012)
Long-term outcome of palliative treatment with self-expanding metal stents for malignant obstructions of the GI tract
Scand. J. Gastroenterol., 47 (12), 1505-1514
DOI 10.3109/00365521.2012.711854

Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2012)
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int. J. Cancer, 131 (3), 570-581
DOI 10.1002/ijc.26392

Sjo OH, Merok MA, Svindland A, Nesbakken A (2012)
Prognostic Impact of Lymph Node Harvest and Lymph Node Ratio in Patients With Colon Cancer
Dis. Colon Rectum, 55 (3), 307-315
DOI 10.1097/DCR.0b013e3182423f62

Sveen A, Agesen TH, Nesbakken A, Meling GI, Rognum TO, Liestol K, Skotheim RI, Lothe RA (2012)
ColoGuidePro: A Prognostic 7-Gene Expression Signature for Stage III Colorectal Cancer Patients
Clin. Cancer Res., 18 (21), 6001-6010
DOI 10.1158/1078-0432.CCR-11-3302

Sveen A, Bakken AC, Agesen TH, Lind GE, Nesbakken A, Nordgard O, Brackmann S, Rognum TO, Lothe RA, Skotheim RI (2012)
The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
Int. J. Cancer, 131 (6), 1479-1485
DOI 10.1002/ijc.27399

Publications 2011

Agesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
Genes Immun., 12 (8), 653-662
DOI 10.1038/gene.2011.43

Andersson T, Lunde OC, Johnson E, Moum T, Nesbakken A (2011)
Long-term functional outcome and quality of life after restorative proctocolectomy with ileo-anal anastomosis for colitis
Colorectal Dis., 13 (4), 431-437
DOI 10.1111/j.1463-1318.2009.02163.x

Danielsen SA, Cekaite L, Agesen TH, Sveen A, Nesbakken A, Thiis-Evensen E, Skotheim RI, Lind GE, Lothe RA (2011)
Phospholipase C Isozymes Are Deregulated in Colorectal Cancer - Insights Gained from Gene Set Enrichment Analysis of the Transcriptome
PLoS One, 6 (9), e24419
DOI 10.1371/journal.pone.0024419

Faerden AE, Sjo OH, Bukholm IRK, Andersen SN, Svindland A, Nesbakken A, Bakka A (2011)
Lymph Node Micrometastases and Isolated Tumor Cells Influence Survival in Stage I and II Colon Cancer
Dis. Colon Rectum, 54 (2), 200-206
DOI 10.1007/DCR.0b013e3181fd4c7c

Holmebakk T, Solbakken A, Mala T, Nesbakken A (2011)
Clinical prediction of survival by surgeons for patients with incurable abdominal malignancy
EJSO, 37 (7), 571-575
DOI 10.1016/j.ejso.2011.02.009

Larssen L, Medhus AW, Hjermstad MJ, Korner H, Glomsaker T, Soberg T, Gleditsch D, Hovde O, Nesbakken A, Tholfsen JK, Skreden K, Hauge T (2011)
Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study
Surg. Endosc., 25 (10), 3162-3169
DOI 10.1007/s00464-011-1680-7

Lind GE, Danielsen SA, Ahlquist T, Merok MA, Andresen K, Skotheim RI, Hektoen M, Rognum TO, Meling GI, Hoff G, Bretthauer M, Thiis-Evensen E, Nesbakken A, Lothe RA (2011)
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
Mol. Cancer, 10, 85
DOI 10.1186/1476-4598-10-85

Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-3978
DOI 10.1038/onc.2011.109

Nesbakken A, Kristinsson J, Svindland A, Lunde OC (2011)
ENDOSCOPIC SNARE RESECTION FOLLOWED BY LASER ABLATION IN THE TREATMENT OF LARGE, SESSILE RECTAL ADENOMAS
Scand. J. Surg., 100 (2), 99-104
DOI 10.1177/145749691110000206

Sjo OH, Berg M, Merok MA, Kolberg M, Svindland A, Lothe RA, Nesbakken A (2011)
Peritoneal Carcinomatosis of Colon Cancer Origin: Highest Incidence in Women and in Patients With Right-Sided Tumors
J. Surg. Oncol., 104 (7), 792-797
DOI 10.1002/jso.21959

Sveen A, Agesen TH, Nesbakken A, Rognum TO, Lothe RA, Skotheim RI (2011)
Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
Genome Med., 3, 32
DOI 10.1186/gm248

Publications 2010

Berg M, Agesen TH, Thiis-Evensen E, Merok MA, Teixeira MR, Vatn MH, Nesbakken A, Skotheim RI, Lothe RA, INFAC-Study Grp (2010)
Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
Mol. Cancer, 9, 100
DOI 10.1186/1476-4598-9-100

Berg M, Danielsen SA, Ahlquist T, Merok MA, Agesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen O, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA (2010)
DNA Sequence Profiles of the Colorectal Cancer Critical Gene Set KRAS-BRAF-PIK3CA-PTEN-TP53 Related to Age at Disease Onset
PLoS One, 5 (11), e13978
DOI 10.1371/journal.pone.0013978

Knaevelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-870
DOI 10.4161/auto.6.7.13033

Kristjansson SR, Jordhoy MS, Nesbakken A, Skovlund E, Bakka A, Johannessen HO, Wyller TB (2010)
Which elements of a comprehensive geriatric assessment (CGA) predict post-operative complications and early mortality after colorectal cancer surgery?
J. Geriatr. Oncol., 1 (2), 57-65
DOI 10.1016/j.jgo.2010.06.001

Kristjansson SR, Nesbakken A, Jordhoy MS, Skovlund E, Audisio RA, Johannessen HO, Bakka A, Wyller TB (2010)
Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: A prospective observational cohort study
Crit. Rev. Oncol./Hematol., 76 (3), 208-217
DOI 10.1016/j.critrevonc.2009.11.002

Ronning B, Wyller TB, Seljeflot I, Jordhoy MS, Skovlund E, Nesbakken A, Kristjansson SR (2010)
Frailty measures, inflammatory biomarkers and post-operative complications in older surgical patients
Age Ageing, 39 (6), 758-761
DOI 10.1093/ageing/afq123

Publications 2009

Baatrup G, Endreseth B, Isaksen V, Kjellmo A, Tveit KM, Nesbakken A (2009)
Preoperative staging and treatment options in T1 rectal adenocarcinoma
Acta Oncol., 48 (3), PII 908367835-342
DOI 10.1080/02841860802657243

Sjo OH, Larsen S, Lunde OC, Nesbakken A (2009)
Short term outcome after emergency and elective surgery for colon cancer
Colorectal Dis., 11 (7), 733-739
DOI 10.1111/j.1463-1318.2008.01613.x

Sovik TT, Aasheim ET, Kristinsson J, Schou CF, Diep LM, Nesbakken A, Mala T (2009)
Establishing Laparoscopic Roux-en-Y Gastric Bypass: Perioperative Outcome and Characteristics of the Learning Curve
Obes. Surg., 19 (2), 158-165
DOI 10.1007/s11695-008-9584-x

Publications 2008

Faerden AE, Sjo O, Andersen SN, Hauglann B, Nazir N, Gravedaug B, Moberg I, Svinland A, Nesbakken A, Bakka A (2008)
Sentinel node mapping does not improve staging of lymph node metastasis in colonic cancer
Dis. Colon Rectum, 51 (6), 891-896
DOI 10.1007/s10350-007-9185-0

Mala T, Nesbakken A (2008)
Morbidity related to the use of a protective stoma in anterior resection for rectal cancer
Colorectal Dis., 10 (8), 785-788
DOI 10.1111/j.1463-1318.2007.01456.x

Sjo OH, Lunde OC, Nygaard K, Sandvik L, Nesbakken A (2008)
Tumour location is a prognostic factor for survival in colonic cancer patients
Colorectal Dis., 10 (1), 33-40
DOI 10.1111/j.1463-1318.2007.01302.x

Publications 2005

Guren MG, Eriksen MT, Wiig JN, Carlsen E, Nesbakken A, Sigurdsson HK, Wibe A, Tveit KM, Norwegian Rectal Cancer Grp (2005)
Quality of life and functional outcome following anterior or abdominoperineal resection for rectal cancer
EJSO, 31 (7), 735-742
DOI 10.1016/j.ejso.2005.05.004

Holmebakk T, Nesbakken A (2005)
SURGERY FOR PILONIDAL DISEASE
Scand. J. Surg., 94 (1), 43-46
DOI 10.1177/145749690509400111

Nesbakken A, Nygaard K, Lunde OC, Blucher J, Gjertsen O, Dullerud R (2005)
Anastomotic leak following mesorectal excision for rectal cancer: true incidence and diagnostic challenges
Colorectal Dis., 7 (6), 576-581
DOI 10.1111/j.1463-1318.2005.00870.x

Publications 2003

Hølmebakk T, Nesbakken A (2003)
Operasjon for sinus pilonidalis sårinfeksjoner, tilhelingstid, residiv og kosmetisk resultat
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2003, Abstrakt 72
BIBSYS 041733290

Hølmebakk T, Nesbakken A (2003)
Fra åpen til laparoskopisk appendektomi: gevinster og tap
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2003, Abstrakt 92
BIBSYS 041733363

Nesbakken A (2003)
Mesorectal excision for rectal cancer: oncological outcome, long term functional outcome, intraoperative and postoperative complications
Department of Gastrointestinal Surgery, Aker University Hospital, Oslo, 1 b. (flere pag.)
BIBSYS 030457769, ISBN 82-8080-035-2

Nesbakken A, Løvig T, Lunde OC, Nygaard K (2003)
Staging of rectal carcinoma with transrectal ultrasonography
In Scandinavian journal of surgery: official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, Vammalen Kirjapeino Oy, Helsinki, 92(2003)2, s.125-9
BIBSYS 041719492

Nesbakken A, Rosseland AR, Lunde OC (2003)
Stenting av malign colon-stenose
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2003, Abstrakt 150
BIBSYS 041734351

Schou CF, Nesbakken A, Rosseland AR, Lunde OC (2003)
Stenting av gastroduodenal stenose
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2003, Abstrakt 74
BIBSYS 041735528

Sjo OH, Nesbakken A, Lunde OC, Nygaard K, Mala T (2003)
Komplikasjoner etter operasjon for cancer coli
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2003, Abstrakt 146
BIBSYS 041735544

Publications 2002

Nesbakken A, Nygaard K, Lunde OC (2002)
Mesorectal excision for rectal cancer: functional outcome after low anterior resectionand colorectal anastomosis without a reservoir
In Colorectal disease, Blackwell, Oxford, 4(2002)nr 3, s. 172-176
BIBSYS 031283713

Nesbakken A, Nygaard K, Westerheim O, Lunde OC, Mala T (2002)
Audit of Intraoperative and early postoperative complications after introduction of mesorectal excision for rectal cancer
Eur. J. Surg., 168 (4), 229-235
DOI 10.1080/11024150260102843

Nesbakken A, Nygaard K, Westerheim O, Lunde OC, Mala T (2002)
Audit of intraoperative and early postoperative complications after introduction of mesorectal excision for rectal cancer
In European journal of surgery, Taylor & Francis, Basingstoke, 168(2002)nr 4, s. 229-235
BIBSYS 03128373x

Nesbakken A, Nygaard K, Westerheim O, Mala T, Lunde OC (2002)
Local recurrence after mesorectal excision for rectal cancer
Eur. J. Surg. Oncol., 28 (2), 126-134
DOI 10.1053/ejso.2001.1231

Nesbakken A, Nygaard K, Westerheim O, Mala T, Lunde OC (2002)
Local recurrence after mesorectal excision for rectal cancer
In European journal of surgical oncology, Academic Press, London, 25(2002)nr 2, s. 126-134
BIBSYS 031283675

Publications 2001

Nesbakken A, Nygaard K, Lunde OC (2001)
Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer
Br. J. Surg., 88 (3), 400-404
DOI 10.1046/j.1365-2168.2001.01719.x

Nesbakken A, Nygaard K, Lunde OC (2001)
Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer - Reply
Br. J. Surg., 88 (9), 1266-1267

Nesbakken A, Nygaard K, Lunde OC (2001)
Outcome and late functional results after anastomotic leakage following mesorectal excision for rectal cancer
In British journal of surgery, Wiley, Oxford, 88(2001)nr 3, s.400-404
BIBSYS 022001042

Publications 2000

Mala T, Lunde OC, Nesbakken A, Aadland E, Stiris M (2000)
Endoskopisk retrograd kolangiopankreatikografi: et fireårsmateriale
In Tidsskrift for Den norske legeforening, Foreningen, Oslo, 120(2000)nr. 5, S. 560-2
BIBSYS 010704272

Nesbakken A, Nygaard K, Bull-Njaa T, Carlsen E, Eri LM (2000)
Bladder and sexual dysfunction after mesorectal excision for rectal cancer
Br. J. Surg., 87 (2), 206-210
DOI 10.1046/j.1365-2168.2000.01357.x

Publications 1989

NESBAKKEN A, HAFFNER J (1989)
COLO-RECTO-ANAL INTUSSUSCEPTION
ACTA CHIR SCAND, 155 (3), 201-204

Publications 1988

NESBAKKEN A, ALHO A, BJERSAND AJ, JENSEN DK, STANGELAND L, WALLOE A (1988)
OPEN TIBIAL FRACTURES TREATED WITH HOFFMANN EXTERNAL FIXATION
Arch. Orthop. Trauma Surg., 107 (4), 248-252
DOI 10.1007/BF00449678