Marianne Skeie
- Head Engineer
- +47 23 07 40 74
Office: A3.3022
Publications 2020
Hsp90 inhibition and co-incubation with pertuzumab induce internalization and degradation of trastuzumab: Implications for use of T-DM1
J Cell Mol Med, 24 (17), 10258-10262
DOI 10.1111/jcmm.15643, PubMed 32672902
Publications 2019
Protein kinase C regulates ErbB3 turnover
Exp Cell Res, 382 (2), 111473
DOI 10.1016/j.yexcr.2019.06.018, PubMed 31233741
Publications 2018
Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation
Exp Cell Res, 371 (1), 139-150
DOI 10.1016/j.yexcr.2018.08.004, PubMed 30098331
Publications 2017
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611
Publications 2012
Pertuzumab Increases 17-AAG-Induced Degradation of ErbB2, and This Effect Is Further Increased by Combining Pertuzumab with Trastuzumab
Pharmaceuticals (Basel), 5 (7), 674-89
DOI 10.3390/ph5070674, PubMed 24281706
Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes
Exp Cell Res, 319 (3), 32-45
DOI 10.1016/j.yexcr.2012.10.010, PubMed 23127513
Publications 2011
A chimeric pre-ubiquitinated EGF receptor is constitutively endocytosed in a clathrin-dependent, but kinase-independent manner
Traffic, 12 (4), 507-20
DOI 10.1111/j.1600-0854.2011.01162.x, PubMed 21226813
Publications 2009
Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization
Mol Cancer Ther, 8 (7), 1885-92
DOI 10.1158/1535-7163.MCT-09-0291, PubMed 19584234
Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2
Mol Cancer Res, 7 (2), 275-84
DOI 10.1158/1541-7786.MCR-07-2183, PubMed 19208749
Publications 2008
Dysregulation of Ack1 inhibits down-regulation of the EGF receptor
Exp Cell Res, 314 (6), 1292-300
DOI 10.1016/j.yexcr.2007.12.017, PubMed 18262180
Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits
Traffic, 10 (2), 235-45
DOI 10.1111/j.1600-0854.2008.00858.x, PubMed 19054389
Publications 2004
Characterization of the Bacillus cereus Nhe enterotoxin
Microbiology (Reading), 150 (Pt 12), 3959-67
DOI 10.1099/mic.0.27359-0, PubMed 15583149