Inger Øynebråten

  • Deputy group leader, Senior scientist; PhD
  • +47 23 07 40 64

Office: RH A3.3019

 

Publications 2024

Gilmour BC, Corthay A, Øynebråten I (2024)
High production of IL-12 by human dendritic cells stimulated with combinations of pattern-recognition receptor agonists
NPJ Vaccines, 9 (1), 83
DOI 10.1038/s41541-024-00869-1, PubMed 38702320

Wold CW, Christopoulos PF, Arias MA, Dzovor DE, Øynebråten I, Corthay A, Inngjerdingen KT (2024)
Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity
Commun Biol, 7 (1), 222
DOI 10.1038/s42003-024-05853-y, PubMed 38396285

Publications 2023

Anderson CC, Bonney EA, Mueller TF, Corthay A, Havele C, Singh NJ, Øynebråten I, Bretscher PA (2023)
On antigen-specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation
Scand J Immunol, 98 (3), e13311
DOI 10.1111/sji.13311, PubMed 38112131

Publications 2022

Eek Mariampillai A, Hauge S, Øynebråten I, Rødland GE, Corthay A, Syljuåsen RG (2022)
Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells
Front Oncol, 12, 981332
DOI 10.3389/fonc.2022.981332, PubMed 36387237

Publications 2021

Frafjord A, Buer L, Hammarström C, Aamodt H, Woldbæk PR, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2021)
The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
Front Immunol, 12, 764596
DOI 10.3389/fimmu.2021.764596, PubMed 34868011

Høydahl LS, Frigstad T, Rasmussen IB, Øynebråten I, Schjetne KW, Andersen JT, Michaelsen TE, Lunde E, Bogen B, Sandlie I (2021)
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine, 39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Publications 2020

Frafjord A, Skarshaug R, Hammarström C, Stankovic B, Dorg LT, Aamodt H, Woldbaek PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2020)
Antibody combinations for optimized staining of macrophages in human lung tumours
Scand J Immunol, 92 (1), e12889
DOI 10.1111/sji.12889, PubMed 32299134

Stankovic B, Aamodt H, Bjørhovde HAK, Müller E, Hammarström C, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2020)
The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases
Scand J Immunol, 92 (2), e12893
DOI 10.1111/sji.12893, PubMed 32433774

Øynebråten I (2020)
Involvement of autophagy in MHC class I antigen presentation
Scand J Immunol, 92 (5), e12978
DOI 10.1111/sji.12978, PubMed 32969499

Publications 2019

Stankovic B, Bjørhovde HAK, Skarshaug R, Aamodt H, Frafjord A, Müller E, Hammarström C, Beraki K, Bækkevold ES, Woldbæk PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2019)
Immune Cell Composition in Human Non-small Cell Lung Cancer
Front Immunol, 9, 3101
DOI 10.3389/fimmu.2018.03101, PubMed 30774636

Publications 2018

Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT (2018)
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Nat Commun, 9 (1), 621
DOI 10.1038/s41467-018-03061-x, PubMed 29434196

Müller E, Speth M, Christopoulos PF, Lunde A, Avdagic A, Øynebråten I, Corthay A (2018)
Both Type I and Type II Interferons Can Activate Antitumor M1 Macrophages When Combined With TLR Stimulation
Front Immunol, 9, 2520
DOI 10.3389/fimmu.2018.02520, PubMed 30450098

Publications 2017

Anderson CC, Bretscher P, Corthay A, Dembic Z, Havele C, Nagy ZA, Øynebråten I (2017)
Immunological Tolerance. Part I of a Report of a Workshop on Foundational Concepts of Immune Regulation
Scand J Immunol, 85 (2), 84-94
DOI 10.1111/sji.12500, PubMed 27885703

Bretscher PA, Corthay A, Anderson CC, Dembic Z, Havele C, Nagy ZA, Øynebråten I (2017)
Immune Class Regulation and Its Medical Significance Part II of a Report of a Workshop on Foundational Concepts of Immune Regulation
Scand J Immunol, 85 (4), 242-250
DOI 10.1111/sji.12525, PubMed 28236642

Kurena B, Müller E, Christopoulos PF, Johnsen IB, Stankovic B, Øynebråten I, Corthay A, Zajakina A (2017)
Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ
Front Immunol, 8, 1667
DOI 10.3389/fimmu.2017.01667, PubMed 29276511

Müller E, Christopoulos PF, Halder S, Lunde A, Beraki K, Speth M, Øynebråten I, Corthay A (2017)
Toll-Like Receptor Ligands and Interferon-γ Synergize for Induction of Antitumor M1 Macrophages
Front Immunol, 8, 1383
DOI 10.3389/fimmu.2017.01383, PubMed 29123526

Obando DFG, Frafjord A, Oynebraten I, Corthay A, Olivo-Marin JC, Meas-Yedid V (2017)
MULTI-STAINING REGISTRATION OF LARGE HISTOLOGY IMAGES
2017 IEEE 14TH INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2017), 345-348

Publications 2016

Andersen AN, Landsverk OJ, Simonsen A, Bogen B, Corthay A, Øynebråten I (2016)
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
Front Immunol, 7, 167
DOI 10.3389/fimmu.2016.00167, PubMed 27242780

Joly-Battaglini A, Hammarström C, Stankovic B, Aamodt H, Stjärne J, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2016)
Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
F1000Res, 5, 38
DOI 10.12688/f1000research.7599.1, PubMed 27081474

Publications 2015

Kuczkowska K, Mathiesen G, Eijsink VG, Øynebråten I (2015)
Lactobacillus plantarum displaying CCL3 chemokine in fusion with HIV-1 Gag derived antigen causes increased recruitment of T cells
Microb Cell Fact, 14, 169
DOI 10.1186/s12934-015-0360-z, PubMed 26494531

Øynebråten I, Barois N, Bergeland T, Küchler AM, Bakke O, Haraldsen G (2015)
Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells
Sci Rep, 5, 9261
DOI 10.1038/srep09261, PubMed 25791723

Publications 2014

Løvås TO, Bruusgaard JC, Øynebråten I, Gundersen K, Bogen B (2014)
DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice
PLoS One, 9 (10), e108069
DOI 10.1371/journal.pone.0108069, PubMed 25299691

Øynebråten I, Hinkula J, Fredriksen AB, Bogen B (2014)
Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3
PLoS One, 9 (8), e104814
DOI 10.1371/journal.pone.0104814, PubMed 25122197

Publications 2012

Rasmussen IB, Oynebråten I, Høydahl LS, Flobakk M, Lunde E, Michaelsen TE, Bogen B, Sandlie I (2012)
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses
Protein Eng Des Sel, 25 (3), 89-96
DOI 10.1093/protein/gzr063, PubMed 22233931

Øynebråten I, Løvås TO, Thompson K, Bogen B (2012)
Generation of antibody-producing hybridomas following one single immunization with a targeted DNA vaccine
Scand J Immunol, 75 (4), 379-88
DOI 10.1111/j.1365-3083.2011.02639.x, PubMed 21955209

Publications 2010

Meen AJ, Øynebråten I, Reine TM, Duelli A, Svennevig K, Pejler G, Jenssen T, Kolset SO (2010)
Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1
J Biol Chem, 286 (4), 2636-47
DOI 10.1074/jbc.M110.151944, PubMed 21075844

Publications 2009

Hol J, Küchler AM, Johansen FE, Dalhus B, Haraldsen G, Oynebråten I (2009)
Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodies
J Biol Chem, 284 (35), 23532-9
DOI 10.1074/jbc.M900874200, PubMed 19578117

Publications 2006

Falkowska-Hansen B, Oynebråten I, Uhlin-Hansen L, Smedsrød B (2006)
Endocytosis and degradation of serglycin in liver sinusoidal endothelial cells
Mol Cell Biochem, 287 (1-2), 43-52
DOI 10.1007/s11010-005-9024-3, PubMed 16733805

Publications 2005

Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
J Immunol, 174 (3), 1657-63
DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929

Øynebråten I, Barois N, Hagelsteen K, Johansen FE, Bakke O, Haraldsen G (2005)
Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol
J Immunol, 175 (8), 5358-69
DOI 10.4049/jimmunol.175.8.5358, PubMed 16210642

Publications 2004

Øynebråten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G (2004)
Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments
Blood, 104 (2), 314-20
DOI 10.1182/blood-2003-08-2891, PubMed 15044249

Publications 2001

Seternes T, Øynebråten I, Sørensen K, Smedsrød B (2001)
Specific endocytosis and catabolism in the scavenger endothelial cells of cod (Gadus morhua L.) generate high-energy metabolites
J Exp Biol, 204 (Pt 9), 1537-46
DOI 10.1242/jeb.204.9.1537, PubMed 11398744

Publications 2000

Oynebråten I, Hansen B, Smedsrød B, Uhlin-Hansen L (2000)
Serglycin secreted by leukocytes is efficiently eliminated from the circulation by sinusoidal scavenger endothelial cells in the liver
J Leukoc Biol, 67 (2), 183-8
DOI 10.1002/jlb.67.2.183, PubMed 10670578

Publications 1997

Hansen B, Oynebraten I, Hansen LU, Smedsrod B (1997)
Elimination of blood monocyte proteoglycan by receptor-mediated endocytosis in rat liver sinusoidal endothelial cells
CELLS OF THE HEPATIC SINUSOID, VOL 6, 373-374

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