Petter Brandal
- Group leader, researcher; MD, PhD
- +47 22 93 58 43
Publications 2024
The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients
J Neurooncol, 169 (1), 137-145
DOI 10.1007/s11060-024-04709-z, PubMed 38762830
Accurate and comprehensive evaluation of O6-methylguanine-DNA methyltransferase promoter methylation by nanopore sequencing
Neuropathol Appl Neurobiol, 50 (3), e12984
DOI 10.1111/nan.12984, PubMed 38783575
Lomustine overdose in a patient with diffuse glioma: symptoms, management and outcome
BMJ Case Rep, 17 (7)
DOI 10.1136/bcr-2024-260450, PubMed 39043464
Diffuse glioma molecular profiling with arterial spin labeling and dynamic susceptibility contrast perfusion MRI: A comparative study
Neurooncol Adv, 6 (1), vdae113
DOI 10.1093/noajnl/vdae113, PubMed 39036439
3D volume growth rate evaluation in the EORTC-BTG-1320 clinical trial for recurrent WHO grade 2 and 3 meningiomas
Neuro Oncol, 26 (7), 1302-1309
DOI 10.1093/neuonc/noae037, PubMed 38452246
CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas
Acta Neuropathol Commun, 12 (1), 55
DOI 10.1186/s40478-023-01695-7, PubMed 38581034
Publications 2023
Survival in a consecutive series of 467 glioblastoma patients: Association with prognostic factors and treatment at recurrence at two independent institutions
PLoS One, 18 (2), e0281166
DOI 10.1371/journal.pone.0281166, PubMed 36730349
Incidence and outcome of pseudoprogression after radiation therapy in glioblastoma patients: A cohort study
Neurooncol Pract, 11 (1), 36-45
DOI 10.1093/nop/npad063, PubMed 38222046
Investigating survival, quality of life and cognition in PROton versus photon therapy for IDH-mutated diffuse grade 2 and 3 GLIOmas (PRO-GLIO): a randomised controlled trial in Norway and Sweden
BMJ Open, 13 (3), e070071
DOI 10.1136/bmjopen-2022-070071, PubMed 36940951
Astrocytoma (CNS WHO grade 4), IDH-mutant with co-occurrence of BRAF p.V600E mutation, and homozygous loss of CDKN2A
Neuropathology, 43 (5), 385-390
DOI 10.1111/neup.12895, PubMed 36754566
The benefit of complete resection of contrast enhancing tumor in glioblastoma patients: A population-based study
Neurooncol Pract, 10 (6), 555-564
DOI 10.1093/nop/npad037, PubMed 38026582
[Glioblastoma in adults]
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.22.0314, PubMed 36718891
Publications 2022
SMART syndrome: two cases highlighting a complex and rare complication of brain irradiation
BMJ Case Rep, 15 (9)
DOI 10.1136/bcr-2022-249599, PubMed 36167430
Idiopathic Duro-Optic Calcification
J Neuroophthalmol, 44 (1), e204
DOI 10.1097/WNO.0000000000001722, PubMed 36255093
Bone mineral density and nutrition in long-term survivors of childhood brain tumors
Clin Nutr ESPEN, 50, 162-169
DOI 10.1016/j.clnesp.2022.05.025, PubMed 35871919
Molecular pathological insights reveal a high number of unfavorable risk patients among children treated for medulloblastoma and CNS-PNET in Oslo 2005-2017
Pediatr Blood Cancer, 69 (9), e29736
DOI 10.1002/pbc.29736, PubMed 35570402
Trabectedin for recurrent WHO grade 2 or 3 meningioma: A randomized phase II study of the EORTC Brain Tumor Group (EORTC-1320-BTG)
Neuro Oncol, 24 (5), 755-767
DOI 10.1093/neuonc/noab243, PubMed 34672349
Oral and dental late effects in long-term survivors of childhood embryonal brain tumors
Support Care Cancer, 30 (12), 10233-10241
DOI 10.1007/s00520-022-07405-8, PubMed 36307656
Taste and smell function in long-term survivors after childhood medulloblastoma/CNS-PNET
Support Care Cancer, 30 (7), 6155-6162
DOI 10.1007/s00520-022-07048-9, PubMed 35426047
Publications 2021
Bilateral calcification of the optic nerve sheath: A diagnostic dilemma
Am J Ophthalmol Case Rep, 22, 101106
DOI 10.1016/j.ajoc.2021.101106, PubMed 33997471
Choroid Plexus Tumors in Children: Long-Term Follow-Up of Consecutive Single-Institutional Series of 59 Patients Treated over a Period of 8 Decades (1939-2020)
World Neurosurg, 158, e810-e819
DOI 10.1016/j.wneu.2021.11.070, PubMed 34823041
Outcome After Treatment of Spinal Ependymoma in Children and Adolescents: Long-Term Follow-up of a Single Consecutive Institutional Series of 33 Patients Treated Over Eight Decades
World Neurosurg, 150, e228-e235
DOI 10.1016/j.wneu.2021.02.131, PubMed 33684583
Outcome after treatment of pediatric supratentorial ependymoma: long-term follow-up of a single consecutive institutional series of 26 patients
Br J Neurosurg, 38 (2), 514-522
DOI 10.1080/02688697.2021.1914821, PubMed 34096810
Real-world validity of randomized controlled phase III trials in newly diagnosed glioblastoma: to whom do the results of the trials apply?
Neurooncol Adv, 3 (1), vdab008
DOI 10.1093/noajnl/vdab008, PubMed 33665615
Neurosarcoidosis resembling multiple meningiomas: A misleading presentation of the disease and diagnostic challenge
Acta Radiol Open, 10 (7), 20584601211036550
DOI 10.1177/20584601211036550, PubMed 34377543
Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma
Acta Oncol, 61 (2), 235-238
DOI 10.1080/0284186X.2021.2022202, PubMed 34970940
Publications 2020
A Nordic-Baltic perspective on indications for proton therapy with strategies for identification of proper patients
Acta Oncol, 59 (10), 1157-1163
DOI 10.1080/0284186X.2020.1817977, PubMed 32902341
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Cancer Discov, 10 (7), 942-963
DOI 10.1158/2159-8290.CD-19-1030, PubMed 32238360
Long-term outcome of posterior fossa medulloblastoma in patients surviving more than 20 years following primary treatment in childhood
Sci Rep, 10 (1), 9371
DOI 10.1038/s41598-020-66328-8, PubMed 32523021
Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
Mol Oncol, 14 (5), 1016-1027
DOI 10.1002/1878-0261.12668, PubMed 32171051
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464
Prediction of survival and progression in glioblastoma patients using temporal perfusion changes during radiochemotherapy
Magn Reson Imaging, 68, 106-112
DOI 10.1016/j.mri.2020.01.012, PubMed 32004711
Adult outcome after treatment of pediatric posterior fossa ependymoma: long-term follow-up of a single consecutive institutional series of 22 patients with more than 5 years of survival
J Neurosurg Pediatr, 26 (1), 22-26
DOI 10.3171/2020.1.PEDS19700, PubMed 32217795
Outcomes in adulthood after neurosurgical treatment of brain tumors in the first 3 years of life: long-term follow-up of a single consecutive institutional series of 97 patients
Childs Nerv Syst, 37 (2), 427-433
DOI 10.1007/s00381-020-04859-1, PubMed 32814984
Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study
Immun Inflamm Dis, 8 (3), 342-359
DOI 10.1002/iid3.315, PubMed 32578964
Neuropsychological functioning in survivors of childhood medulloblastoma/CNS-PNET: The role of secondary medical complications
Clin Neuropsychol, 36 (3), 600-625
DOI 10.1080/13854046.2020.1794045, PubMed 32729777
Unmet rehabilitation needs in 86% of Norwegian paediatric embryonal brain tumour survivors
Acta Paediatr, 109 (9), 1875-1886
DOI 10.1111/apa.15188, PubMed 31977119
Publications 2019
Disseminated central nervous system hemangioblastoma in a patient with no clinical or genetic evidence of von Hippel-Lindau disease-a case report and literature review
Acta Neurochir (Wien), 161 (2), 343-349
DOI 10.1007/s00701-019-03800-z, PubMed 30652202
[Need for rehabilitation after brain tumour]
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.19.0268, PubMed 31238657
18F-Fluciclovine PET/CT in Suspected Residual or Recurrent High-Grade Glioma
Clin Nucl Med, 44 (8), 605-611
DOI 10.1097/RLU.0000000000002641, PubMed 31274605
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology, 61 (5), 545-555
DOI 10.1007/s00234-019-02173-5, PubMed 30712139
Adult outcome after neurosurgical treatment of brain tumours in the first year of life: long-term follow-up of a single consecutive institutional series of 34 patients
Acta Neurochir (Wien), 161 (9), 1793-1798
DOI 10.1007/s00701-019-04014-z, PubMed 31309304
Neurosurgical treatment of pediatric pleomorphic xanthoastrocytomas: long-term follow-up of a single-institution, consecutive series of 12 patients
J Neurosurg Pediatr, 23 (4), 512-516
DOI 10.3171/2018.11.PEDS18449, PubMed 30738389
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Pediatr Blood Cancer, 66 (10), e27910
DOI 10.1002/pbc.27910, PubMed 31264356
Normal tissue complication probability models in plan evaluation of children with brain tumors referred to proton therapy
Acta Oncol, 58 (10), 1416-1422
DOI 10.1080/0284186X.2019.1643496, PubMed 31364899
Publications 2018
MGMT Gene Promoter Methylation Status - Assessment of Two Pyrosequencing Kits and Three Methylation-specific PCR Methods for their Predictive Capacity in Glioblastomas
Cancer Genomics Proteomics, 15 (6), 437-446
DOI 10.21873/cgp.20102, PubMed 30343277
Survival Associations Using Perfusion and Diffusion Magnetic Resonance Imaging in Patients With Histologic and Genetic Defined Diffuse Glioma World Health Organization Grades II and III
J Comput Assist Tomogr, 42 (5), 807-815
DOI 10.1097/RCT.0000000000000742, PubMed 29901512
Neurosurgical treatment of gangliogliomas in children and adolescents: long-term follow-up of a single-institution series of 32 patients
Acta Neurochir (Wien), 160 (6), 1207-1214
DOI 10.1007/s00701-018-3550-8, PubMed 29680921
Pyrosequencing Analysis of MGMT Promoter Methylation in Meningioma
Cancer Genomics Proteomics, 15 (5), 379-385
DOI 10.21873/cgp.20096, PubMed 30194078
Publications 2017
IDH-mutant giant cell glioblastoma: A neglected tumor variant?
Clin Neuropathol, 36 (6), 293-295
DOI 10.5414/NP301054, PubMed 29035191
Outcome for children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor (CNS-PNET) - a retrospective analysis spanning 40 years of treatment
Acta Oncol, 56 (5), 698-705
DOI 10.1080/0284186X.2017.1301679, PubMed 28325133
Publications 2016
Consensus Report From the Stockholm Pediatric Proton Therapy Conference
Int J Radiat Oncol Biol Phys, 96 (2), 387-392
DOI 10.1016/j.ijrobp.2016.06.2446, PubMed 27598806
Novel fusion genes and chimeric transcripts in ependymal tumors
Genes Chromosomes Cancer, 55 (12), 944-953
DOI 10.1002/gcc.22392, PubMed 27401149
Persistent bone marrow depression following short-term treatment with temozolomide
BMJ Case Rep, 2016
DOI 10.1136/bcr-2016-215797, PubMed 27130558
Symptomatic spinal metastasis from intracranial glioblastoma multiforme - Two illustrative cases and a review of the literature
Acta Oncol, 55 (9-10), 1236-1238
DOI 10.3109/0284186X.2016.1161824, PubMed 27174685
Publications 2015
Posterior fossa ependymoblastoma diagnosed in the second month of life: uneventful 12 years survival after gross total resection followed by chemotherapy
Springerplus, 4, 389
DOI 10.1186/s40064-015-1178-1, PubMed 26251773
Neurosurgical treatment of brain tumors in the first 6 months of life: long-term follow-up of a single consecutive institutional series of 30 patients
Childs Nerv Syst, 31 (12), 2283-90
DOI 10.1007/s00381-015-2792-5, PubMed 26174616
Posterior fossa ependymoma in childhood: 60 years event-free survival after partial resection—a case report
Childs Nerv Syst, 31 (9), 1573-6
DOI 10.1007/s00381-015-2766-7, PubMed 26047947
Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?
Neuro Oncol, 17 (10), 1365-73
DOI 10.1093/neuonc/nov039, PubMed 25795305
Publications 2014
Neurosurgical treatment of pediatric low-grade midbrain tumors: a single consecutive institutional series of 15 patients
J Neurosurg Pediatr, 14 (6), 598-603
DOI 10.3171/2014.9.PEDS1462, PubMed 25325421
Pediatric spinal ependymomas: an unpredictable and puzzling disease. Long-term follow-up of a single consecutive institutional series of ten patients
Childs Nerv Syst, 30 (12), 2083-8
DOI 10.1007/s00381-014-2491-7, PubMed 25079883
Genomic characterization of ependymomas reveals 6q loss as the most common aberration
Oncol Rep, 32 (2), 483-90
DOI 10.3892/or.2014.3271, PubMed 24939246
Novel CSF1-S100A10 fusion gene and CSF1 transcript identified by RNA sequencing in tenosynovial giant cell tumors
Int J Oncol, 44 (5), 1425-32
DOI 10.3892/ijo.2014.2326, PubMed 24604026
Publications 2013
Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors
Neuro Oncol, 16 (2), 320-2
DOI 10.1093/neuonc/not230, PubMed 24311631
Neurosurgical treatment of oligodendroglial tumors in children and adolescents: a single-institution series of 35 consecutive patients
J Neurosurg Pediatr, 12 (3), 241-6
DOI 10.3171/2013.6.PEDS12586, PubMed 23870041
Expansion of multipotent stem cells from the adult human brain
PLoS One, 8 (8), e71334
DOI 10.1371/journal.pone.0071334, PubMed 23967194
Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion
Oncol Rep, 30 (4), 1549-52
DOI 10.3892/or.2013.2623, PubMed 23877199
Are melanomas averse to cerebellum? Cerebellar metastases in a surgical series
Acta Neurol Scand, 130 (1), 1-10
DOI 10.1111/ane.12206, PubMed 24313862
Publications 2012
MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
J Transl Med, 10, 36
DOI 10.1186/1479-5876-10-36, PubMed 22390413
Sampling requirements in DCE-MRI based analysis of high grade gliomas: simulations and clinical results
J Magn Reson Imaging, 37 (4), 818-29
DOI 10.1002/jmri.23866, PubMed 23086710
Publications 2011
Genomic aberrations in pediatric gliomas and embryonal tumors
Genes Chromosomes Cancer, 50 (10), 788-99
DOI 10.1002/gcc.20898, PubMed 21717527
Multiple chromosomal monosomies are characteristic of giant cell ependymoma
Hum Pathol, 42 (12), 2042-6
DOI 10.1016/j.humpath.2011.02.012, PubMed 21683982
Genomic aberrations in diffuse low-grade gliomas
Genes Chromosomes Cancer, 50 (6), 409-20
DOI 10.1002/gcc.20866, PubMed 21412929
Molecular cytogenetic analysis of a gliosarcoma with osseous metaplasia
Cytogenet Genome Res, 134 (2), 88-95
DOI 10.1159/000326804, PubMed 21555877
Similar cytogenetic findings in two synchronous secondary peripheral chondrosarcomas in a patient with multiple osteochondromas
Cancer Genet, 204 (12), 677-81
DOI 10.1016/j.cancergen.2011.10.013, PubMed 22285020
Publications 2010
Genotypic and phenotypic classification of cancer: How should the impact of the two diagnostic approaches best be balanced?
Genes Chromosomes Cancer, 49 (9), 763-74
DOI 10.1002/gcc.20792, PubMed 20607708
Brain tumor stem cells maintain overall phenotype and tumorigenicity after in vitro culturing in serum-free conditions
Neuro Oncol, 12 (12), 1220-30
DOI 10.1093/neuonc/noq102, PubMed 20843775
Publications 2009
Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience
Acta Oncol, 48 (8), 1165-72
DOI 10.3109/02841860903032809, PubMed 19863225
t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma
Genes Chromosomes Cancer, 48 (12), 1051-6
DOI 10.1002/gcc.20706, PubMed 19760602
Genomic aberrations in 80 cases of primary glioblastoma multiforme: Pathogenetic heterogeneity and putative cytogenetic pathways
Genes Chromosomes Cancer, 48 (10), 908-24
DOI 10.1002/gcc.20690, PubMed 19603525
Publications 2008
Detection of a t(1;22)(q23;q12) translocation leading to an EWSR1-PBX1 fusion gene in a myoepithelioma
Genes Chromosomes Cancer, 47 (7), 558-64
DOI 10.1002/gcc.20559, PubMed 18383210
Publications 2006
Molecular cytogenetic analysis of archival and fresh solid tumor samples
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 417, 1 b. (flere pag.)
BIBSYS 061045322, ISBN 82-8072-229-7
Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology
J Pathol, 208 (3), 388-94
DOI 10.1002/path.1879, PubMed 16308870
Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas
Mod Pathol, 19 (2), 186-94
DOI 10.1038/modpathol.3800499, PubMed 16258504
Publications 2005
Chromosome 7 abnormalities are common in chordomas
Cancer Genet Cytogenet, 160 (1), 15-21
DOI 10.1016/j.cancergencyto.2004.11.016, PubMed 15949565
Chromosome abnormalities in juxtaglomerular cell tumors
Cancer, 104 (3), 504-10
DOI 10.1002/cncr.21205, PubMed 15968688
Publications 2004
Molecular cytogenetic characterization of tenosynovial giant cell tumors
Neoplasia, 6 (5), 578-83
DOI 10.1593/neo.04202, PubMed 15548367
Publications 2003
Molecular cytogenetic characterization of desmoid tumors
Cancer Genet Cytogenet, 146 (1), 1-7
DOI 10.1016/s0165-4608(03)00122-5, PubMed 14499689