Susanne G. Dudman
- Group leader, Senior medical officer OUS, Professor University of Oslo; MD, PhD
- +4723 07 11 55
Academic positions
- Professor of Virology, Inst. of Clinical Medicine, University of Oslo (UiO)
- Leader Norwegian Society for Virology (www.nvfvirologi.net)
- Councilor European Society for Clinical Virology (www.escv.eu)
- Editor of Journal of Clinical Virology (https://www.sciencedirect.com/journal/journal-of-clinical-virology/about/editorial-board)
- Leader of digital teaching for students in medical microbiology, Faculty of Medicine, UiO
Academic interests
- Virology, infectious disease epidemiology and effect of vaccines against viral infections
- Pathogenesis of viral infections and virus infections among immunosuppressed patients
Background
- Since 2019 associate Professor UiO, Virology and Senior Medical Officer, Oslo University Hospital, Department of Microbiology
- Senior Medical Officer at Folkehelseinstituttet 2007-2018
- Senior Medical Officer/ associate professor at Akershus University Hospital 2005-2007
- MD at Dep. Microbiology Akershus University Hospital (Ahus) 2002-2005
- PhD/ assistant professor at UiO 1997-2002
- MD at Dep. Infectious Diseases, Ullevål University Hospital 1995-1996
- MD, Dep. Medicine, Hedmark Central hospital 1991-1995
- Cand. med 1991, University of Oslo
- Dr. med/ PhD 2003, UiO
Project funding
- Norwegian SARS-CoV-2 study – Virological, clinical and immunological characterisation of inpatients during the COVID-19 outbreak. Research Council of Norway grant 312780
- An effectiveness trial to evaluate protection of pregnant women by a HEV vaccine in Bangladesh and risk factors for severe HEV infection. RCN grant 248143
- Intrauterine infections risk of stillbirths and neurodevelopmental disorders. RCN no 213916
Collaboration, networks and societies
- Collaboration with research groups at Folkehelseinstituttet, UiO and Oslo University hospital, as well as Østfold Hospital and Ahus among others in Norway
- Collaboration with researchers in Bangladesh, Nepal, Europe
- Research partners: icddr,b i Dhaka/Matlab Bangladesh HEV vaccine trial (www.icddrb.org). Walter Reed/Armed Forces Research Institute of Medical Sciences Research Unit Nepal
- Member of European Society for Clinical Virology (ESCV) council
- Member of Eur. Soc. Clinical Microbiology and Infectious Diseases (ESCMID)
- Member of European Non-Polio Enterovirus Network (ENPEN)
- Member of Norwegian Society of Virology board
- Member of Norwegian Society for Medical Microbiology and Nor. Soc. Infectious Diseases and Nor. Soc. For Internal Medicine
Publications 2024
Receipt of hepatitis E vaccine and fetal loss in rural Bangladesh: further analysis of a double-blind, cluster-randomised, controlled trial
Lancet Glob Health, 12 (8), e1300-e1311
DOI 10.1016/S2214-109X(24)00193-1, PubMed 39030061
Hepatitis E vaccine and fetal loss: the potential pathophysiological basis - Authors' reply
Lancet Glob Health, 12 (11), e1760
DOI 10.1016/S2214-109X(24)00412-1, PubMed 39424567
Trends in the enterovirus surveillance in Oslo, Norway before and during the COVID-19 pandemic
Frontiers in Virology, 3, 1-9
DOI 10.3389/fviro.2023.1343781, PublikaID 492
Emergence of enterovirus D68 in a Norwegian paediatric population 2012-2022
Frontiers in Virology, 4, 1-7
DOI 10.3389/fviro.2024.1358963, PublikaID 493
Clinical Evaluation of the VirClia IgM/IgG Chemiluminescence Tests for the Diagnosis of Tick-Borne Encephalitis in an Endemic Part of Norway
Viruses, 16 (9)
DOI 10.3390/v16091505, PubMed 39339981
Epidemiological and Clinical Insights into the Enterovirus D68 Upsurge in Europe 2021-2022 and Emergence of Novel B3-Derived Lineages, ENPEN Multicentre Study
J Infect Dis, 230 (4), e917-e928
DOI 10.1093/infdis/jiae154, PubMed 38547499
Safety and effectiveness of a recombinant hepatitis E vaccine in women of childbearing age in rural Bangladesh: a phase 4, double-blind, cluster-randomised, controlled trial
Lancet Glob Health, 12 (8), e1288-e1299
DOI 10.1016/S2214-109X(24)00192-X, PubMed 39030060
Publications 2023
Antibiotic Consumption in a Cohort of Hospitalized Adults with Viral Respiratory Tract Infection
Antibiotics (Basel), 12 (4)
DOI 10.3390/antibiotics12040788, PubMed 37107150
Tracing the adaptive evolution of SARS-CoV-2 during vaccine roll-out in Norway
Virus Evol, 10 (1), vead081
DOI 10.1093/ve/vead081, PubMed 38205440
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572
The Molecular Epidemiology of Enterovirus in a Birth Cohort in Nepal
Microbiology Research, 14 (3), 909-917
DOI 10.3390/microbiolres14030063, PublikaID 475
Immunogenicity and safety of a two-dose regimen with hepatitis E virus vaccine in healthy adults in rural Bangladesh: A randomized, double-blind, controlled, phase 2/pilot trial
Vaccine, 41 (5), 1059-1066
DOI 10.1016/j.vaccine.2022.12.064, PubMed 36599736
Publications 2022
Hepatitis E Virus (HEV) Synopsis: General Aspects and Focus on Bangladesh
Viruses, 15 (1)
DOI 10.3390/v15010063, PubMed 36680103
Maternal cytomegalovirus infection and delayed language development in children at 3 years of age-a nested case-control study in a large population-based pregnancy cohort
PLoS One, 17 (12), e0278623
DOI 10.1371/journal.pone.0278623, PubMed 36455052
Clinical Outcome of Viral Respiratory Tract Infections in Hospitalized Adults in Norway: High Degree of Inflammation and Need of Emergency Care for Cases With Respiratory Syncytial Virus
Front Med (Lausanne), 9, 866494
DOI 10.3389/fmed.2022.866494, PubMed 35572955
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet, 31 (23), 3945-3966
DOI 10.1093/hmg/ddac158, PubMed 35848942
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518
Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?
Front Pharmacol, 13, 1062408
DOI 10.3389/fphar.2022.1062408, PubMed 36506522
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699
Stability and Feasibility of Dried Blood Spots for Hepatitis E Virus Serology in a Rural Setting
Viruses, 14 (11)
DOI 10.3390/v14112525, PubMed 36423134
Publications 2021
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903
Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
Emerg Infect Dis, 27 (6), 1616-1626
DOI 10.3201/eid2706.203096, PubMed 34013874
Etiology of viral respiratory tract infections in hospitalized adults, and evidence of the high frequency of prehospitalization antibiotic treatment in Norway
Health Sci Rep, 4 (4), e403
DOI 10.1002/hsr2.403, PubMed 34646942
Tick-transmitted co-infections among erythema migrans patients in a general practice setting in Norway: a clinical and laboratory follow-up study
BMC Infect Dis, 21 (1), 1044
DOI 10.1186/s12879-021-06755-8, PubMed 34625049
Genetic diversity of rotavirus strains circulating in Norway before and after the introduction of rotavirus vaccination in children
J Med Virol, 94 (6), 2624-2631
DOI 10.1002/jmv.27484, PubMed 34837228
The incidence of infectious diseases and viruses other than SARS-CoV-2 amongst hospitalised children in Oslo, Norway during the Covid-19 pandemic 2020-2021
J Clin Virol Plus, 2 (1), 100060
DOI 10.1016/j.jcvp.2021.100060, PubMed 35262033
Diversity of Rotavirus Strains in Children; Results From a Community-Based Study in Nepal
Front Med (Lausanne), 8, 712326
DOI 10.3389/fmed.2021.712326, PubMed 34660624
Genetic Diversity of Astrovirus in Children From a Birth Cohort in Nepal
Front Microbiol, 11, 588707
DOI 10.3389/fmicb.2020.588707, PubMed 33613461
Increased inflammatory markers reflecting fibrogenesis are independently associated with cardiac involvement in hospitalized COVID-19 patients
J Infect, 82 (5), 186-230
DOI 10.1016/j.jinf.2021.01.017, PubMed 33516748
Publications 2020
Parvovirus B19 DNAemia in pregnant women in relation to perinatal death: A nested case-control study within a large population-based pregnancy cohort
Acta Obstet Gynecol Scand, 99 (7), 856-864
DOI 10.1111/aogs.13801, PubMed 31925774
Effect of rotavirus vaccine implementation on the prevalence of coinfections with enteric viruses in Norway
J Med Virol, 92 (12), 3151-3156
DOI 10.1002/jmv.26013, PubMed 32410230
A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts
J Med Virol, 92 (8), 1065-1074
DOI 10.1002/jmv.25659, PubMed 31883139
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med, 289 (4), 523-531
DOI 10.1111/joim.13178, PubMed 32976665
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843
Aseptic meningitis outbreak associated with echovirus 4 in Northern Europe in 2013-2014
J Clin Virol, 129, 104535
DOI 10.1016/j.jcv.2020.104535, PubMed 32652478
Aseptic meningitis outbreak associated with echovirus 4 in Northern Europe in 2013-2014
Journal of Clinical Virology, 129, 104535
DOI 10.1016/j.jcv.2020.104535, PublikaID 345
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675
HEV study protocol : design of a cluster-randomised, blinded trial to assess the safety, immunogenicity and effectiveness of the hepatitis E vaccine HEV 239 (Hecolin) in women of childbearing age in rural Bangladesh
BMJ Open, 10 (1), e033702
DOI 10.1136/bmjopen-2019-033702, PubMed 31959609
Publications 2019
Circulation of non-polio enteroviruses in 24 EU and EEA countries between 2015 and 2017: a retrospective surveillance study
Lancet Infect Dis, 20 (3), 350-361
DOI 10.1016/S1473-3099(19)30566-3, PubMed 31870905
Hepatitis E in Pregnant Women and the Potential Use of HEV Vaccine to Prevent Maternal Infection and Mortality
Curr. Trop. Med. Rep., 6 (4), 197-204
DOI 10.1007/s40475-019-00193-y
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview
Pediatr Infect Dis J, 38 (1), 16-21
DOI 10.1097/INF.0000000000002188, PubMed 30234793
Immunity to varicella zoster virus among pregnant women in the Norwegian Mother and Child Cohort Study
PLoS One, 14 (8), e0221084
DOI 10.1371/journal.pone.0221084, PubMed 31408478
Current practices for respiratory syncytial virus surveillance across the EU/EEA Member States, 2017
Euro Surveill, 24 (40)
DOI 10.2807/1560-7917.ES.2019.24.40.1900157, PubMed 31595876
TBE in Norway
In The TBE Book, Global Health Press, Singapore
PublikaID 322, ISBN 9789811409141
Publications 2018
Maternal and congenital cytomegalovirus infections in a population-based pregnancy cohort study
APMIS, 126 (12), 899-906
DOI 10.1111/apm.12899, PubMed 30378168
A woman in her 30s with severe headache
Tidsskr. Nor. Laegeforen., 138 (9), 841-844
A woman in her thirties with severe headache
Tidsskr Nor Laegeforen, 138 (9)
DOI 10.4045/tidsskr.17.0444, PubMed 29808663
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe
J Clin Virol, 101, 11-17
DOI 10.1016/j.jcv.2018.01.008, PubMed 29414181
Management strategies of enterovirus D68 outbreaks: current perspectives
Virus Adaptation and Treatment, 10, 1-7
PublikaID 323
Response to third rubella vaccine dose
Hum Vaccin Immunother, 14 (10), 2472-2477
DOI 10.1080/21645515.2018.1475814, PubMed 29771601
Publications 2017
High incidence of maternal parvovirus B19 infection in a large unselected population-based pregnancy cohort in Norway
J Clin Virol, 94, 57-62
DOI 10.1016/j.jcv.2017.07.010, PubMed 28759773
Rotavirus detection in bulk stool and rectal swab specimens in children with acute gastroenteritis in Norway
J Clin Virol, 97, 50-53
DOI 10.1016/j.jcv.2017.10.017, PubMed 29107766
Circulation and diagnostics of Puumala virus in Norway: nephropatia epidemica incidence and rodent population dynamics
APMIS, 125 (8), 732-742
DOI 10.1111/apm.12712, PubMed 28585306
Can Norway be kept free of rubella and measles?
Tidsskr. Nor. Laegeforen., 137 (14-15), 1004-1006
Can Norway be kept free from rubella and measles?
Tidsskr Nor Laegeforen, 137 (14-15)
DOI 10.4045/tidsskr.17.0047, PubMed 28828847
Publications 2016
Hepatitis E in Norway: seroprevalence in humans and swine
Epidemiol Infect, 145 (1), 181-186
DOI 10.1017/S0950268816002144, PubMed 27671461
Rapid Bedside Inactivation of Ebola Virus for Safe Nucleic Acid Tests
J Clin Microbiol, 54 (10), 2521-9
DOI 10.1128/JCM.00346-16, PubMed 27466385
Pulmonary changes in Norwegian fatal cases of pandemic influenza H1N1 (2009) infection: a morphologic and molecular genetic study
Influenza Other Respir Viruses, 10 (6), 525-531
DOI 10.1111/irv.12410, PubMed 27413002
Publications 2015
Risk of exposure to ticks (Ixodidae) and the prevalence of tick-borne encephalitis virus (TBEV) in ticks in Southern Poland
Ticks Tick Borne Dis, 6 (3), 356-63
DOI 10.1016/j.ttbdis.2015.02.010, PubMed 25838177
Toxoplasma prevalence among pregnant women in Norway: a cross-sectional study
APMIS, 123 (4), 321-5
DOI 10.1111/apm.12354, PubMed 25628065
Prevalence of tick-borne encephalitis virus in Ixodes ricinus ticks from three islands in north-western Norway
APMIS, 123 (9), 759-64
DOI 10.1111/apm.12412, PubMed 26126504
Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn 2014
Euro Surveill, 20 (10), 21062
DOI 10.2807/1560-7917.es2015.20.10.21062, PubMed 25788251
Publications 2014
High frequency of enterovirus D68 in children hospitalised with respiratory illness in Norway, autumn 2014
Influenza Other Respir Viruses, 9 (2), 59-63
DOI 10.1111/irv.12300, PubMed 25534826
Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques
J Virol, 88 (22), 13418-28
DOI 10.1128/JVI.01219-14, PubMed 25210172
Seroprevalence of antibodies to tick-borne encephalitis virus and Anaplasma phagocytophilum in healthy adults from western Norway
Infect Dis (Lond), 47 (1), 52-6
DOI 10.3109/00365548.2014.959044, PubMed 25342575
Detection of specific IgG antibodies in blood donors and tick-borne encephalitis virus in ticks within a non-endemic area in southeast Norway
Scand J Infect Dis, 46 (3), 181-4
DOI 10.3109/00365548.2013.865140, PubMed 24447253
Publications 2013
Susceptibility to cytomegalovirus, parvovirus B19 and age-dependent differences in levels of rubella antibodies among pregnant women
J Med Virol, 86 (5), 820-6
DOI 10.1002/jmv.23757, PubMed 24114849
[Intravenous immunoglobulin treatment]
Tidsskr Nor Laegeforen, 133 (8), 826-7
DOI 10.4045/tidsskr.13.0410, PubMed 23612094
Within-patient emergence of the influenza A(H1N1)pdm09 HA1 222G variant and clear association with severe disease, Norway
Euro Surveill, 18 (3)
PubMed 23351651
Within-patient emergence of the influenza A(H1N1) pdm09 HA1 222G variant and clear association with severe disease, Norway
Eurosurveillance, 18 (3), 20369-13
Tick-borne encephalitis virus and louping-ill virus may co-circulate in Southern Norway
Vector Borne Zoonotic Dis, 13 (10), 762-8
DOI 10.1089/vbz.2012.1023, PubMed 23808981
Publications 2012
Prevalence of tick borne encephalitis virus in tick nymphs in relation to climatic factors on the southern coast of Norway
Parasit Vectors, 5, 177
DOI 10.1186/1756-3305-5-177, PubMed 22913287
[Outbreaks of measles following increased travelling and low vaccination coverage]
Tidsskr Nor Laegeforen, 132 (8), 937-9
DOI 10.4045/tidsskr.11.1269, PubMed 22562324
Measles virus genotyping an important tool in measles outbreak investigation in Norway, 2011
Eurosurveillance, 17 (50), 20340-19
Measles virus genotyping an important tool in measles outbreak investigation in Norway, 2011
Euro Surveill, 17 (50)
PubMed 23241234
Characterization in vitro and in vivo of pandemic (H1N1) 2009 influenza viruses isolated from patients
J Virol, 86 (17), 9361-8
DOI 10.1128/JVI.01214-12, PubMed 22718834
Age-dependent prevalence of antibodies cross-reactive to the influenza A(H3N2) variant virus in sera collected in Norway in 2011
Euro Surveill, 17 (19)
PubMed 22607964
Age-dependent prevalence of antibodies cross-reactive to the influenza A(H3N2) variant virus in sera collected in Norway in 2011
Eurosurveillance, 17 (19), 20170-9
Publications 2011
A five-year perspective on the situation of haemorrhagic fever with renal syndrome and status of the hantavirus reservoirs in Europe, 2005-2010
Eurosurveillance, 16 (36), 19961-22
A five-year perspective on the situation of haemorrhagic fever with renal syndrome and status of the hantavirus reservoirs in Europe, 2005-2010
Euro Surveill, 16 (36)
DOI 10.2807/ese.16.36.19961-en, PubMed 21924118
Ongoing outbreak of measles in Oslo, Norway, January-February 2011
Eurosurveillance, 16 (8), 9-11
Ongoing outbreak of measles in Oslo, Norway, January-February 2011
Euro Surveill, 16 (8)
PubMed 21371412
[Wrongly informed about influenza serology]
Tidsskr Nor Laegeforen, 131 (2), 110-1
DOI 10.4045/tidsskr.10.1298, PubMed 21267019
Avian-type receptor-binding ability can increase influenza virus pathogenicity in macaques
J Virol, 85 (24), 13195-203
DOI 10.1128/JVI.00859-11, PubMed 21937653
Rituximab blocks protective serologic response to influenza A (H1N1) 2009 vaccination in lymphoma patients during or within 6 months after treatment
Blood, 118 (26), 6769-71
DOI 10.1182/blood-2011-08-372649, PubMed 22058114
Publications 2010
Observed association between the HA1 mutation D222G in the 2009 pandemic influenza A(H1N1) virus and severe clinical outcome, Norway 2009-2010
Euro Surveill, 15 (9)
DOI 10.2807/ese.15.09.19498-en, PubMed 20214869
Observed association between the HA1 mutation D222G in the 2009 pandemic influenza A(H1N1) virus and severe clinical outcome, Norway 2009-2010
Eurosurveillance, 15 (9), 19498-8
Author's reply: Association of D222G substitution in haemagglutinin of 2009 pandemic influenza A (H1N1) with severe disease
Eurosurveillance, 15 (14), 19535-17
Fatal and mild primary dengue virus infections imported to Norway from Africa and south-east Asia, 2008-2010
Eurosurveillance, 15 (38), 19666-5
Fatal and mild primary dengue virus infections imported to Norway from Africa and south-east Asia, 2008-2010
Euro Surveill, 15 (38)
DOI 10.2807/ese.15.38.19666-en, PubMed 20929653
High prevalence of antibodies to the 2009 pandemic influenza A(H1N1) virus in the Norwegian population following a major epidemic and a large vaccination campaign in autumn 2009
Euro Surveill, 15 (31)
PubMed 20738992
High prevalence of antibodies to the 2009 pandemic influenza A(H1N1) virus in the Norwegian population following a major epidemic and a large vaccination campaign in autumn 2009
Eurosurveillance, 15 (31), 19633-7
Publications 2009
Oseltamivir-resistant influenza A(H1N1) viruses detected in Europe during season 2007-8 had epidemiologic and clinical characteristics similar to co-circulating susceptible A(H1N1) viruses
Euro Surveill, 14 (46)
PubMed 19941797
OSELTAMIVIR-RESISTANT INFLUENZA A(H1N1) VIRUSES DETECTED IN EUROPE DURING SEASON 2007-8 HAD EPIDEMIOLOGIC AND CLINICAL CHARACTERISTICS SIMILAR TO CO-CIRCULATING SUSCEPTIBLE A(H1N1) VIRUSES
Eurosurveillance, 14 (46), 19412-20
Sales of oseltamivir in Norway prior to the emergence of oseltamivir resistant influenza A(H1N1) viruses in 2007-08
Virol J, 6, 54
DOI 10.1186/1743-422X-6-54, PubMed 19435505
Oseltamivir-resistant influenza viruses A (H1N1), Norway, 2007-08
Emerg Infect Dis, 15 (2), 155-62
DOI 10.3201/eid1502.081031, PubMed 19193257
[Disease caused by the new influenza A(H1N1) virus]
Tidsskr Nor Laegeforen, 129 (17), 1736-9
DOI 10.4045/tidsskr.09.0748, PubMed 19756053
Publications 2008
[Viral drug resistance]
Tidsskr Nor Laegeforen, 128 (22), 2597-600
PubMed 19023374
[Resistance in influenza viruses]
Tidsskr Nor Laegeforen, 128 (22), 2601-6
PubMed 19023375
Emergence of resistance to oseltamivir among influenza A(H1N1) viruses in Europe
Euro Surveill, 13 (5)
DOI 10.2807/ese.13.05.08026-en, PubMed 18445375
Publications 2007
HIV related and non-HIV related mortality before and after the introduction of highly active antiretroviral therapy (HAART) in Norway compared to the general population
Scand J Infect Dis, 39 (1), 51-7
DOI 10.1080/00365540600904779, PubMed 17366013
Publications 2006
[HIV/AIDS--from lethal syndrome to chronic disease]
Tidsskr Nor Laegeforen, 126 (23), 3121-4
PubMed 17160119
[Whooping cough--an increasing problem in Norway]
Tidsskr Nor Laegeforen, 126 (3), 305-8
PubMed 16440035