Marius Trøseid

  • Group leader, ass. professor; MD, PhD
  • +47 23 07 18 98
 

Publications 2024

Bai X, Nielsen SD, Kunisaki KM, Trøseid M (2024)
Pulmonary comorbidities in people with HIV- the microbiome connection
Curr Opin HIV AIDS, 19 (5), 246-252
DOI 10.1097/COH.0000000000000871, PubMed 38935049

Barratt-Due A, Pettersen K, Børresdatter-Dahl T, Holter JC, Grønli RH, Dyrhol-Riise AM, Lerum TV, Holten AR, Tonby K, Trøseid M, Skjønsberg OH, Granerud BK, Heggelund L, Kildal AB, Schjalm C, Aaløkken TM, Aukrust P, Ueland T, Mollnes TE, Halvorsen B, NOR‐Solidarity study groupThe Norwegian SARS‐CoV‐2 study group (2024)
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241

Bratseth V, Nendl A, Raju SC, Holm K, Broch K, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2024)
Gut dysbiosis and neutrophil extracellular traps in chronic heart failure
Int J Cardiol, 419, 132689 (in press)
DOI 10.1016/j.ijcard.2024.132689, PubMed 39489348

De Bortoli A, Nordøy I, Connelly JP, Viermyr HK, Bjerkreim RH, Broch K, Olsen PAS, Gude E, Fevang B, Jørgensen SF, Trøseid M, Steen T, Aukrust P, Andreassen AK, Skarpengland T (2024)
Diagnostics, treatment and outcomes of cardiac sarcoidosis in a Norwegian cohort
Int J Cardiol, 400, 131809
DOI 10.1016/j.ijcard.2024.131809, PubMed 38272129

Halvorsen B, Viermyr HK, Ueland T, Sagen EL, Michelsen AE, Bjerkeli V, Nor-Solidarity Study Group, Tveita AA, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Trøseid M, Dahl TB, Aukrust P, Gregersen I (2024)
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108

Hites M, Massonnaud CR, Lapique EL, Belhadi D, Jamard S, Goehringer F, Danion F, Reignier J, de Castro N, Garot D, Lacombe K, Tolsma V, Faure E, Malvy D, Staub T, Courjon J, Cazenave-Roblot F, Dyrhol Riise AM, Leturnier P, Martin-Blondel G, Roger C, Akinosoglou K, Moing VL, Piroth L, Sellier P et al. (2024)
Tixagevimab-cilgavimab (AZD7442) for the treatment of patients hospitalized with COVID-19 (DisCoVeRy): A phase 3, randomized, double-blind, placebo-controlled trial
J Infect, 88 (3), 106120
DOI 10.1016/j.jinf.2024.106120, PubMed 38367705

Hoel H, Dahl TB, Yang K, Skeie LG, Michelsen AE, Ueland T, Damås JK, Dyrhol-Riise AM, Fevang B, Yndestad A, Aukrust P, Trøseid M, Sandanger Ø (2024)
Chronic HIV Infection Increases Monocyte NLRP3 Inflammasome-Dependent IL-1α and IL-1β Release
Int J Mol Sci, 25 (13)
DOI 10.3390/ijms25137141, PubMed 39000248

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714

Murphy SL, Balzer NR, Ranheim T, Sagen EL, Huse C, Bjerkeli V, Michelsen AE, Finbråten AK, Heggelund L, Dyrhol-Riise AM, Tveita A, Holten AR, Trøseid M, Ueland T, Ulas T, Aukrust P, Barratt-Due A, Halvorsen B, Dahl TB (2024)
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465

Nendl A, Andersen GØ, Seljeflot I, Trøseid M, Awoyemi A (2024)
Intestinal fatty acid binding protein is associated with infarct size and cardiac function in acute heart failure following myocardial infarction
Open Heart, 11 (2)
DOI 10.1136/openhrt-2024-002868, PubMed 39277188

Patrick-Brown TDJH, Barratt-Due A, Trøseid M, Dyrhol-Riise AM, Nezvalova-Henriksen K, Kåsine T, Aukrust P, Olsen IC, NOR Solidarity consortium (2024)
The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis
Commun Med (Lond), 4 (1), 231
DOI 10.1038/s43856-024-00650-4, PubMed 39533001

Patrick-Brown TDJH, Bourner J, Kali S, Trøseid M, Yazdanpanah Y, Olliaro P, Olsen IC (2024)
Experiences and challenges with the new European Clinical Trials Regulation
Trials, 25 (1), 3
DOI 10.1186/s13063-023-07869-x, PubMed 38167484

Raju SC, Molinaro A, Awoyemi A, Jørgensen SF, Braadland PR, Nendl A, Seljeflot I, Ueland PM, McCann A, Aukrust P, Vestad B, Mayerhofer C, Broch K, Gullestad L, Lappegård KT, Halvorsen B, Kristiansen K, Hov JR, Trøseid M (2024)
Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
Genome Med, 16 (1), 27
DOI 10.1186/s13073-024-01296-6, PubMed 38331891

Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2024)
Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
Nat Med, 30 (1), 303
DOI 10.1038/s41591-023-02529-8, PubMed 37587221

Trøseid M (2024)
Viral, Host Factors or Both as COVID-19 Biomarkers
Clin Infect Dis, 78 (6), 1504-1505
DOI 10.1093/cid/ciad779, PubMed 38376208

Trøseid M, Molinaro A, Gelpi M, Vestad B, Kofoed KF, Fuchs A, Køber L, Holm K, Benfield T, Ueland PM, Hov JR, Nielsen SD, Knudsen AD (2024)
Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV
J Infect Dis, 229 (3), 898-907
DOI 10.1093/infdis/jiad604, PubMed 38195204

Trøseid M, Nielsen SD, Vujkovic-Cvijin I (2024)
Gut microbiome and cardiometabolic comorbidities in people living with HIV
Microbiome, 12 (1), 106
DOI 10.1186/s40168-024-01815-y, PubMed 38877521

Ueland T, Nkele I, Hoel H, Lockman S, Michelsen AE, Moshomo T, Aukrust P, Mohammed T, Trøseid M, Mosepele M (2024)
Markers of extracellular matrix degradation and inflammasome activation are associated with carotid plaques in virally suppressed people with HIV in Botswana
AIDS (in press)
DOI 10.1097/QAD.0000000000004014, PubMed 39283741

Viermyr HK, Halvorsen B, Sagen EL, Michelsen AE, Barrat-Due A, Kåsine T, Nezvalova-Henriksen K, Dyrhol-Riise AM, Nor‐Solidarity Consortium, Lerum TV, Müller F, Tonby K, Tveita A, Aukrust P, Trøseid M, Ueland T, Dahl TB (2024)
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800

Publications 2023

Braadland PR, Bergquist A, Kummen M, Bossen L, Engesæter LK, Reims HM, Björk I, Grzyb K, Abildgaard A, Småstuen MC, Folseraas T, Trøseid M, Ulvik A, Ueland PM, Melum E, Line PD, Høivik ML, Grønbæk H, Karlsen TH, Vesterhus M, Hov JR (2023)
Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
J Hepatol, 79 (4), 955-966
DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069

Juul FE, Hov JER, Trøseid M, Johnsen PH, Valeur J (2023)
[Gut microbiota and intestinal disease –a sober warning]
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.23.0121, PubMed 37376933

Knudsen AD, Eskelund CW, Benfield T, Zhao Y, Gelpi M, Køber L, Trøseid M, Kofoed KF, Ostrowski SR, Reilly C, Borges ÁH, Grønbæk K, Nielsen SD (2023)
Clonal hematopoiesis of indeterminate potential in persons with HIV
AIDS, 38 (4), 487-495
DOI 10.1097/QAD.0000000000003788, PubMed 37976039

Knudsen AD, Fuchs A, Benfield T, Gerstoft J, Køber L, Trøseid M, Kofoed KF, Nielsen SD (2023)
Coronary Artery Disease in Persons With Human Immunodeficiency Virus Without Detectable Viral Replication
Open Forum Infect Dis, 10 (7), ofad298
DOI 10.1093/ofid/ofad298, PubMed 37441354

Mikaeloff F, Gelpi M, Benfeitas R, Knudsen AD, Vestad B, Høgh J, Hov JR, Benfield T, Murray D, Giske CG, Mardinoglu A, Trøseid M, Nielsen SD, Neogi U (2023)
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Elife, 12
DOI 10.7554/eLife.82785, PubMed 36794912

Moreno E, Trøseid M, Vujkovic-Cvijin I, Marchetti G, Martín-Pedraza L, Serrano-Villar S (2023)
Editorial: Targeting the microbiota to attenuate chronic inflammation
Front Immunol, 14, 1202222
DOI 10.3389/fimmu.2023.1202222, PubMed 37153550

Murphy SL, Halvorsen B, Holter JC, Huse C, Tveita A, Trøseid M, Hoel H, Kildal AB, Holten AR, Lerum TV, Skjønsberg OH, Michelsen AE, Aaløkken TM, NOR-SOLIDARITY Consortium, The Norwegian SARS-CoV-2 study group investigators, Tonby K, Lind A, Dudman S, Granerud BK, Heggelund L, Bøe S, Dyrholt-Riise AM, Aukrust P, Barratt-Due A, Ueland T, Dahl TB (2023)
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572

Nendl A, Raju SC, Broch K, Mayerhofer CCK, Holm K, Halvorsen B, Lappegård KT, Moscavitch S, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2023)
Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
Front Cardiovasc Med, 10, 1160030
DOI 10.3389/fcvm.2023.1160030, PubMed 37332580

Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2023)
Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
Nat Med, 29 (7), 1738-1749
DOI 10.1038/s41591-023-02407-3, PubMed 37464040

Terzić V, Levoyer L, Figarella M, Bigagli E, Mercier N, De Gastines L, Gibowski S, Trøseid M, Demotes J, Olsen IC, Hites M, Ader F, Lopez JRA, Mentré F, Espérou H, Costagliola D, Røttingen JA, Poissy J, Rozé JC, Warris A, O'Leary J, Fernandes RM, Assoumou L, Hankard R, Turner MA et al. (2023)
Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia
Br J Clin Pharmacol, 89 (4), 1318-1328
DOI 10.1111/bcp.15669, PubMed 36680782

Thudium RF, Arentoft NS, Hoel H, Afzal S, von Stemann JH, Forman JL, Wilcke JT, Benfield T, Trøseid M, Borges ÁH, Ostrowski SR, Vestbo J, Kunisaki KM, Jensen JS, Nielsen SD (2023)
Elevated Levels of Interleukin-1β and Interleukin-10 Are Associated With Faster Lung Function Decline in People With Well-Treated Human Immunodeficiency Virus
J Infect Dis, 228 (8), 1080-1088
DOI 10.1093/infdis/jiad233, PubMed 37366576

Trøseid M, Arribas JR (2023)
Which trial do we need? Management of elderly, fragile, fully vaccinated patients hospitalized for SARS-CoV-2 infection
Clin Microbiol Infect, 29 (4), 419-421
DOI 10.1016/j.cmi.2023.01.006, PubMed 36641054

Trøseid M, Arribas JR, Assoumou L, Holten AR, Poissy J, Terzić V, Mazzaferri F, Baño JR, Eustace J, Hites M, Joannidis M, Paiva JA, Reuter J, Püntmann I, Patrick-Brown TDJH, Westerheim E, Nezvalova-Henriksen K, Beniguel L, Dahl TB, Bouscambert M, Halanova M, Péterfi Z, Tsiodras S, Rezek M, Briel M et al. (2023)
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655

Trøseid M, Holter JC, Holm K, Vestad B, Sazonova T, Granerud BK, Dyrhol-Riise AM, Holten AR, Tonby K, Kildal AB, Heggelund L, Tveita A, Bøe S, Müller KE, Jenum S, Hov JR, Ueland T, Norwegian SARS-CoV-2 study group (2023)
Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
Crit Care, 27 (1), 69
DOI 10.1186/s13054-023-04356-2, PubMed 36814280

Ueland T, Michelsen AE, Tveita AA, Kåsine T, Dahl TB, Finbråten AK, Holten AR, Skjønsberg OH, Mathiessen A, Henriksen KN, Trøseid M, Aaløkken TM, Halvorsen B, Dyrhol-Riise AM, Barratt-Due A, Aukrust P (2023)
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350

Ueland T, Waagsbø B, Berge RK, Trøseid M, Aukrust P, Damås JK (2023)
Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression
Viruses, 15 (7)
DOI 10.3390/v15071613, PubMed 37515299

Ueland T, Äikäs LAO, Dahl TB, Gregersen I, Olsen MB, Michelsen A, Schanke Y, Holopainen M, Ruhanen H, Singh S, NOR-SOLIDARITY Consortium, Tveita AA, Finbråten AK, Heggelund L, Trøseid M, Dyrhol-Riise AM, Nyman TA, Holven KB, Öörni K, Aukrust P, Halvorsen B (2023)
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413

Publications 2022

Aune SK, Bonnevie-Svendsen M, Nyborg C, Trøseid M, Seljeflot I, Hisdal J, Helseth R (2022)
Gut Leakage and Cardiac Biomarkers after Prolonged Strenuous Exercise
Med Sci Sports Exerc, 54 (9), 1476-1482
DOI 10.1249/MSS.0000000000002948, PubMed 35482788

Awoyemi A, Hov JR, Trøseid M (2022)
Phenylacetylglutamine From the Gut Microbiota: A Future Therapeutic Target in Heart Failure?
Circ Heart Fail, 16 (1), e010222
DOI 10.1161/CIRCHEARTFAILURE.122.010222, PubMed 36524473

Gelpi M, Vestad B, Raju SC, Hansen SH, Høgh J, Midttun Ø, Ueland PM, Ueland T, Benfield T, Kofoed KF, Hov JR, Trøseid M, Nielsen SD (2022)
Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
J Infect Dis, 225 (11), 1948-1954
DOI 10.1093/infdis/jiac018, PubMed 35089326

Gregersen I, Ueland T, Holter JC, Olsen MB, Michelsen AE, Murphy SL, Tveita AA, Henriksen KN, Hoel H, Nordberg LB, Holten AR, Edvardsen T, Yang K, Heggelund L, Trøseid M, Müller F, Kildal AB, Dyrhol-Riise AM, Barratt-Due A, Dahl TB, Aukrust P, Halvorsen B, NOR-SOLIDARITY consortium, The Norwegian SARS-CoV-2 Study Group investigators (2022)
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188

Hentzien M, Owen A, Strub-Wourgaft N, Pérez-Casas C, Trøseid M, Calmy A (2022)
Rethinking treatment paradigms for the deployment of SARS-CoV-2 antiviral drugs on the shifting landscape of new variants
Front Microbiol, 13, 998287
DOI 10.3389/fmicb.2022.998287, PubMed 36312942

Knudsen AD, Bouazzi R, Afzal S, Gelpi M, Benfield T, Høgh J, Thomsen MT, Trøseid M, Nordestgaard BG, Nielsen SD (2022)
Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls
BMC Infect Dis, 22 (1), 451
DOI 10.1186/s12879-022-07450-y, PubMed 35546661

Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130

Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437

Murphy SL, Halvorsen B, Barratt-Due A, Dyrhol-Riise AM, Aukrust P, Trøseid M, Dahl TB (2022)
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611

Storm-Larsen C, Hande LN, Kummen M, Thunhaug H, Vestad B, Hansen SH, Hovland A, Trøseid M, Lappegård KT, Hov JR (2022)
Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
Scand J Clin Lab Invest, 82 (5), 363-370
DOI 10.1080/00365513.2022.2102540, PubMed 35913798

Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep, 12 (1), 22378
DOI 10.1038/s41598-022-26759-x, PubMed 36572703

Suarez-Zdunek MA, Høgh J, Kirkegaard-Klitbo DM, Jensen AMR, Rupert A, Trøseid M, Gerstoft J, Nielsen SD, Knudsen AD (2022)
High incidence of subclinical peripheral artery disease in people with HIV
AIDS, 36 (10), 1355-1362
DOI 10.1097/QAD.0000000000003252, PubMed 35608109

Trøseid M, Dahl TB, Holter JC, Kildal AB, Murphy SL, Yang K, Quiles-Jiménez A, Heggelund L, Müller KE, Tveita A, Michelsen AE, Bøe S, Holten AR, Hoel H, Mathiessen A, Aaløkken TM, Fevang B, Granerud BK, Tonby K, Henriksen KN, Lerum TV, Müller F, Skjønsberg OH, Barratt-Due A, Dyrhol-Riise AM et al. (2022)
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589

Trøseid M, Diallo A, Hites M, Røttingen JA, Yazdanpanah Y (2022)
Accelerating clinical trial implementation in the context of the COVID-19 pandemic: author's response
Clin Microbiol Infect, 28 (5), 743-744
DOI 10.1016/j.cmi.2021.12.014, PubMed 35031489

Trøseid M, Hentzien M, Ader F, Cardoso SW, Arribas JR, Molina JM, Mueller N, Hites M, Bonnet F, Manuel O, Costagliola D, Grinsztejn B, Olsen IC, Yazdapanah Y, Calmy A, EU RESPONSE, COMBINE (2022)
Immunocompromised patients have been neglected in COVID-19 trials: a call for action
Clin Microbiol Infect, 28 (9), 1182-1183
DOI 10.1016/j.cmi.2022.05.005, PubMed 35623577

Tveita A, Murphy SL, Holter JC, Kildal AB, Michelsen AE, Lerum TV, Kaarbø M, Heggelund L, Holten AR, Finbråten AK, Müller KE, Mathiessen A, Bøe S, Fevang B, Granerud BK, Tonby K, Lind A, Dudman SG, Henriksen KN, Müller F, Skjønsberg OH, Trøseid M, Barratt-Due A, Dyrhol-Riise AM, Aukrust P et al. (2022)
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699

Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063

Publications 2021

Aune SK, Byrkjeland R, Solheim S, Arnesen H, Trøseid M, Awoyemi A, Seljeflot I, Helseth R (2021)
Gut related inflammation and cardiorespiratory fitness in patients with CAD and type 2 diabetes: a sub-study of a randomized controlled trial on exercise training
Diabetol Metab Syndr, 13 (1), 36
DOI 10.1186/s13098-021-00655-2, PubMed 33794977

Aune SK, Cwikiel J, Flaa A, Arnesen H, Solheim S, Awoyemi A, Trøseid M, Seljeflot I, Helseth R (2021)
Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease
Cells, 10 (9)
DOI 10.3390/cells10092193, PubMed 34571843

Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol, 56 (4), 443-452
DOI 10.1080/00365521.2021.1880627, PubMed 33583308

Drivsholm N, Knudsen AD, Faurholt-Jepsen M, Midttun Ø, Trøseid M, Kirkegaard-Klitbo DM, Ueland PM, Nielsen SD, Gelpi M (2021)
Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV
J Acquir Immune Defic Syndr, 87 (2), e177-e181
DOI 10.1097/QAI.0000000000002664, PubMed 33633032

EU-Response investigators group, Diallo A, Trøseid M, Simensen VC, Boston A, Demotes J, Olsen IC, Chung F, Paiva JA, Hites M, Ader F, Arribas JR, Baratt-Due A, Melien Ø, Tacconelli E, Staub T, Greil R, Tsiodras S, Briel M, Esperou H, Mentré F, Eustace J, Saillard J, Delmas C, LeMestre S et al. (2021)
Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group
Clin Microbiol Infect, 28 (1), 1-5
DOI 10.1016/j.cmi.2021.10.011, PubMed 34763056

Hustad NB, Degerud HM, Hjelmerud I, Fraz MSA, Nordøy I, Trøseid M, Fevang B, Aukrust P, Jørgensen SF (2021)
Real-World Experiences With Facilitated Subcutaneous Immunoglobulin Substitution in Patients With Hypogammaglobulinemia, Using a Three-Step Ramp-Up Schedule
Front Immunol, 12, 670547
DOI 10.3389/fimmu.2021.670547, PubMed 34012453

Ianevski A, Yao R, Zusinaite E, Lello LS, Wang S, Jo E, Yang J, Ravlo E, Wang W, Lysvand H, Løseth K, Oksenych V, Tenson T, Windisch MP, Poranen MM, Nieminen AI, Nordbø SA, Fenstad MH, Grødeland G, Aukrust P, Trøseid M, Kantele A, Lastauskienė E, Vitkauskienė A, Legrand N et al. (2021)
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections
Viruses, 13 (12)
DOI 10.3390/v13122489, PubMed 34960758

Kåsine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg Å, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR et al. (2021)
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368

Lerum TV, Maltzahn NN, Aukrust P, Trøseid M, Henriksen KN, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Haugli M, Blomberg B, Kittang BR, Johannessen A, Hannula R, Aballi S, Kildal AB, Eiken R, Dahl TB, Lund-Johansen F, Müller F, Rodriguez JR, Meltzer C, Einvik G, Ueland T, Olsen IC, NOR-SOLIDARITY Consortium et al. (2021)
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380

Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Trøseid M, Tjønnfjord GE, Iversen PO (2021)
Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
Sci Rep, 11 (1), 11593
DOI 10.1038/s41598-021-90976-z, PubMed 34078971

Thudium RF, Knudsen AD, Von Stemann JH, Hove-Skovsgaard M, Hoel H, Mocroft A, Reekie J, Ronit A, Gerstoft J, Vestbo J, Trøseid M, Borges ÁH, Ostrowski SR, Nielsen SD (2021)
Independent Association of Interleukin 6 With Low Dynamic Lung Function and Airflow Limitation in Well-Treated People With Human Immunodeficiency Virus
J Infect Dis, 223 (10), 1690-1698
DOI 10.1093/infdis/jiaa600, PubMed 33141877

Thudium RF, Ringheim H, Ronit A, Hoel H, Benfield T, Mocroft A, Gerstoft J, Trøseid M, Borges ÁH, Ostrowski SR, Vestbo J, Nielsen SD (2021)
Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV
Front Immunol, 12, 668113
DOI 10.3389/fimmu.2021.668113, PubMed 33936110

Trøseid M, Hites M, Barratt-Due A, Ader F, Yazdanpanah Y (2021)
Assessing the evidence on remdesivir
Lancet Infect Dis, 21 (12), 1630-1631
DOI 10.1016/S1473-3099(21)00695-2, PubMed 34838222

Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007

Publications 2020

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Gelpi M, Ueland PM, Trøseid M, Mocroft A, Lebech AM, Ullum H, Midttun Ø, Lundgren J, Nielsen SD (2020)
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus
J Infect Dis, 221 (3), 419-427
DOI 10.1093/infdis/jiz465, PubMed 31538186

Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
Clin Infect Dis, 71 (8), e359-e367
DOI 10.1093/cid/ciz1235, PubMed 31894240

Hoel H, Heggelund L, Reikvam DH, Stiksrud B, Ueland T, Michelsen AE, Otterdal K, Muller KE, Lind A, Muller F, Dudman S, Aukrust P, Dyrhol-Riise AM, Holter JC, Trøseid M (2020)
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med, 289 (4), 523-531
DOI 10.1111/joim.13178, PubMed 32976665

Hoel H, Ueland T, Hove-Skovsgaard M, Hartling HJ, Gelpi M, Benfield T, Ullum H, Michelsen AE, Aukrust P, Nielsen SD, Trøseid M (2020)
Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
Open Forum Infect Dis, 7 (2), ofaa033
DOI 10.1093/ofid/ofaa033, PubMed 32055642

Hoel H, Ueland T, Knudsen A, Kjær A, Michelsen AE, Sagen EL, Halvorsen B, Yndestad A, Nielsen SD, Aukrust P, Lebech AM, Trøseid M (2020)
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280

Hove-Skovsgaard M, Abildgaard J, Gelpi M, Gaardbo JC, Kolte L, Ullum H, Trøseid M, Lindegaard B, Nielsen SD (2020)
No evidence of a synergistic effect of HIV infection and diabetes mellitus type 2 on fat distribution, plasma adiponectin or inflammatory markers
BMC Infect Dis, 20 (1), 882
DOI 10.1186/s12879-020-05594-3, PubMed 33238950

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Kummen M, Thingholm LB, Rühlemann MC, Holm K, Hansen SH, Moitinho-Silva L, Liwinski T, Zenouzi R, Storm-Larsen C, Midttun Ø, McCann A, Ueland PM, Høivik ML, Vesterhus M, Trøseid M, Laudes M, Lieb W, Karlsen TH, Bang C, Schramm C, Franke A, Hov JR (2020)
Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
Gastroenterology, 160 (5), 1784-1798.e0
DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530

Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail, 7 (2), 456-466
DOI 10.1002/ehf2.12596, PubMed 31978943

Nordøy I, Fraz MAS, Trøseid M, Fevang B, Aukrust P (2020)
[Elevated serum ferritin is not only a sign of liver failure]
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0376, PubMed 32463199

Reikvam DH, Meyer-Myklestad MH, Trøseid M, Stiksrud B (2020)
Probiotics to manage inflammation in HIV infection
Curr Opin Infect Dis, 33 (1), 34-43
DOI 10.1097/QCO.0000000000000612, PubMed 31789692

Trøseid M (2020)
[When COVID-19 meets the African health service]
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0283, PubMed 32378852

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Trøseid M, Lutro O, Ormaasen V (2020)
[Experimental treatment for COVID-19 should be undertaken in randomised studies]
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0282, PubMed 32378863

Publications 2019

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2019)
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Mayerhofer CCK, Awoyemi A, Hov JR, Trøseid M, Broch K (2019)
Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
ESC Heart Fail, 6 (3), 557-558
DOI 10.1002/ehf2.12437, PubMed 31034162

Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356

Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315

Troseid M (2019)
Bone Marrow Transplantation - a cure for HIV?
Tidsskr. Nor. Laegeforen., 139 (7), 580

Trøseid M (2019)
[Bone marrow transplantation – a cure for HIV?]
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0199, PubMed 30969050

Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965

Publications 2018

Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
J Acquir Immune Defic Syndr, 78 (4), 450-457
DOI 10.1097/QAI.0000000000001693, PubMed 29874201

Awoyemi A, Trøseid M, Arnesen H, Solheim S, Seljeflot I (2018)
Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study
Diabetol Metab Syndr, 10, 59
DOI 10.1186/s13098-018-0360-3, PubMed 30038669

Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
Liver Int, 39 (2), 371-381
DOI 10.1111/liv.13979, PubMed 30269440

Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976

Kummen M, Mayerhofer CCK, Vestad B, Broch K, Awoyemi A, Storm-Larsen C, Ueland T, Yndestad A, Hov JR, Trøseid M (2018)
Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
J Am Coll Cardiol, 71 (10), 1184-1186
DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360

Mayerhofer CCK, Awoyemi AO, Moscavitch SD, Lappegård KT, Hov JR, Aukrust P, Hovland A, Lorenzo A, Halvorsen S, Seljeflot I, Gullestad L, Trøseid M, Broch K (2018)
Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
ESC Heart Fail, 5 (5), 977-984
DOI 10.1002/ehf2.12332, PubMed 30088346

Missailidis C, Neogi U, Stenvinkel P, Trøseid M, Nowak P, Bergman P (2018)
The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages
AIDS, 32 (12), 1589-1598
DOI 10.1097/QAD.0000000000001813, PubMed 29620717

Troseid M, Nordoy I, Fevang B, Aukrust P (2018)
Tenders for HIV medicines are not academically justified
Tidsskr. Nor. Laegeforen., 138 (20), 1912-1913

Trøseid M, Nordøy I, Fevang B, Aukrust P (2018)
[Tendering for HIV drugs is not clinically justified]
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0808, PubMed 30539614

Publications 2017

Gelpi M, Hartling HJ, Ueland PM, Ullum H, Trøseid M, Nielsen SD (2017)
Tryptophan catabolism and immune activation in primary and chronic HIV infection
BMC Infect Dis, 17 (1), 349
DOI 10.1186/s12879-017-2456-z, PubMed 28511640

Haissman JM, Haugaard AK, Ostrowski SR, Berge RK, Hov JR, Trøseid M, Nielsen SD (2017)
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
BMC Infect Dis, 17 (1), 445
DOI 10.1186/s12879-017-2547-x, PubMed 28645263

Hove-Skovsgaard M, Gaardbo JC, Kolte L, Winding K, Seljeflot I, Svardal A, Berge RK, Gerstoft J, Ullum H, Trøseid M, Nielsen SD (2017)
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation
BMC Infect Dis, 17 (1), 234
DOI 10.1186/s12879-017-2334-8, PubMed 28356058

Hovland A, Nestvold T, Bohov P, Trøseid M, Aukrust P, Berge RK, Waage-Nielsen E, Retterstøl K, Lappegård KT (2017)
Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
Scand J Clin Lab Invest, 77 (8), 628-633
DOI 10.1080/00365513.2017.1393691, PubMed 29069988

Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M (2017)
Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
J Card Fail, 23 (9), 666-671
DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889

Prebensen C, Trøseid M, Ueland T, Dahm A, Sandset PM, Aaberge I, Waalen K, Dyrhol-Riise AM, Taskén K, Kvale D (2017)
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
PLoS One, 12 (5), e0176527
DOI 10.1371/journal.pone.0176527, PubMed 28464042

Trøseid M (2017)
Gut microbiota and acute coronary syndromes: ready for use in the emergency room?
Eur Heart J, 38 (11), 825-827
DOI 10.1093/eurheartj/ehx005, PubMed 28159962

Publications 2016

Haissman JM, Haugaard AK, Knudsen A, Kristoffersen US, Seljeflot I, Pedersen KK, Lebech AM, Hasbak P, Kjær A, Ostrowski SR, Gerstoft J, Trøseid M, Nielsen SD (2016)
Marker of Endothelial Dysfunction Asymmetric Dimethylarginine Is Elevated in HIV Infection but Not Associated With Subclinical Atherosclerosis
J Acquir Immune Defic Syndr, 73 (5), 507-513
DOI 10.1097/QAI.0000000000001148, PubMed 27509250

Haissman JM, Knudsen A, Hoel H, Kjær A, Kristoffersen US, Berge RK, Katzenstein TL, Svardal A, Ueland T, Aukrust P, Lebech AM, Nielsen SD, Trøseid M (2016)
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection
J Acquir Immune Defic Syndr, 71 (2), 130-6
DOI 10.1097/QAI.0000000000000843, PubMed 26413854

Jespersen S, Pedersen KK, Anesten B, Zetterberg H, Fuchs D, Gisslén M, Hagberg L, Trøseid M, Nielsen SD (2016)
Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
BMC Infect Dis, 16, 176
DOI 10.1186/s12879-016-1510-6, PubMed 27103116

Jortveit J, Dahlslett T, Kvien EH, Lundblad R, Trøseid M, Beitnes JO (2016)
[A man in his 20s with abdominal pain and heart murmurs]
Tidsskr Nor Laegeforen, 136 (3), 238-40
DOI 10.4045/tidsskr.15.0790, PubMed 26860384

Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597

Knudsen A, Christensen TE, Thorsteinsson K, Ghotbi AA, Hasbak P, Lebech AM, Nielsen SD, Hov JR, Berge R, Ripa RS, Kjær A, Trøseid M (2016)
Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT
J Acquir Immune Defic Syndr, 72 (4), e83-5
DOI 10.1097/QAI.0000000000001044, PubMed 27152465

Kummen M, Holm K, Anmarkrud JA, Nygård S, Vesterhus M, Høivik ML, Trøseid M, Marschall HU, Schrumpf E, Moum B, Røsjø H, Aukrust P, Karlsen TH, Hov JR (2016)
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816

Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2016)
Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
United European Gastroenterol J, 5 (4), 532-541
DOI 10.1177/2050640616663453, PubMed 28588885

Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510

Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
J Acquir Immune Defic Syndr, 73 (2), 138-48
DOI 10.1097/QAI.0000000000001080, PubMed 27632144

Trøseid M, Hov JR, Nestvold TK, Thoresen H, Berge RK, Svardal A, Lappegård KT (2016)
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
Metab Syndr Relat Disord, 14 (4), 197-201
DOI 10.1089/met.2015.0120, PubMed 27081744

Publications 2015

Hartling HJ, Birch C, Gaardbo JC, Hove M, Trøseid M, Clausen MR, Gerstoft J, Ullum H, Nielsen SD (2015)
T-cell homeostasis in chronic HCV-infected patients treated with interferon and ribavirin or an interferon-free regimen
APMIS, 123 (10), 903-11
DOI 10.1111/apm.12429, PubMed 26279289

Hov JE, Trøseid M (2015)
Personalised medicine targeting the gut microbiota?
Tidsskr Nor Laegeforen, 135 (7), 624
DOI 10.4045/tidsskr.14.1431, PubMed 25899345

Hov JER, Troseid M (2015)
Personalized intestinal flora medicine?
Tidsskr. Nor. Laegeforen., 135 (7), 624

Nowak P, Troseid M, Avershina E, Barqasho B, Neogi U, Holm K, Hov JR, Noyan K, Vesterbacka J, Svärd J, Rudi K, Sönnerborg A (2015)
Gut microbiota diversity predicts immune status in HIV-1 infection
AIDS, 29 (18), 2409-18
DOI 10.1097/QAD.0000000000000869, PubMed 26355675

Pedersen KK, Eiersted MR, Gaardbo JC, Pedersen M, Gerstoft J, Troseid M, Nielsen SD (2015)
Lower Self-Reported Quality of Life in HIV-Infected Patients on cART and With Low Comorbidity Compared With Healthy Controls
J Acquir Immune Defic Syndr, 70 (1), 16-22
DOI 10.1097/QAI.0000000000000697, PubMed 26017659

Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571

Troseid M (2015)
[Antiretroviral drugs against HIV infections]
Tidsskr Nor Laegeforen, 135 (11), 1054
DOI 10.4045/tidsskr.15.0156, PubMed 26080783

Troseid M (2015)
AIDS epidemic Defeats, victories and new challenges
Tidsskr. Nor. Laegeforen., 135 (11), 1059
DOI 10.4045/tidsskr.15.0533

Trøseid M, Nestvold TK, Nielsen EW, Thoresen H, Seljeflot I, Lappegård KT (2015)
Soluble CD14 is associated with markers of vascular dysfunction in bariatric surgery patients
Metab Syndr Relat Disord, 13 (3), 119-24
DOI 10.1089/met.2014.0111, PubMed 25562385

Publications 2014

Lind A, Brekke K, Pettersen FO, Mollnes TE, Trøseid M, Kvale D (2014)
A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers
PLoS One, 9 (1), e85604
DOI 10.1371/journal.pone.0085604, PubMed 24416431

Manner IW, Baekken M, Oektedalen O, Kvale D, Nowak P, Nielsen SD, Os I, Trøseid M (2014)
Plasma lipopolysaccharide and triglycerides are independently associated and both markers correlate with the development of metabolic syndrome in HIV infection
J Acquir Immune Defic Syndr, 65 (4), e158-61
DOI 10.1097/QAI.0000000000000055, PubMed 24577189

Pedersen KK, Manner IW, Seljeflot I, Kvale D, Os I, Gerstoft J, Nielsen SD, Trøseid M (2014)
Monocyte activation, but not microbial translocation, is independently associated with markers of endovascular dysfunction in HIV-infected patients receiving cART
J Acquir Immune Defic Syndr, 67 (4), 370-4
DOI 10.1097/QAI.0000000000000339, PubMed 25226210

Pettersen PS, Brox IK, Naman E, Bruun JN, Dyrhol-Riise AM, Trøseid M, Johannessen A (2014)
Antiretroviral treatment failure predicts mortality in rural Tanzania
Int J STD AIDS, 26 (9), 633-9
DOI 10.1177/0956462414548460, PubMed 25122578

Trøseid M, Ditlevsen S, Hvid T, Gerstoft J, Grøndahl T, Pedersen BK, Nielsen SD, Lindegaard B (2014)
Reduced trunk fat and triglycerides after strength training are associated with reduced LPS levels in HIV-infected individuals
J Acquir Immune Defic Syndr, 66 (2), e52-4
DOI 10.1097/QAI.0000000000000132, PubMed 24608893

Trøseid M, Manner IW, Pedersen KK, Haissman JM, Kvale D, Nielsen SD (2014)
Microbial translocation and cardiometabolic risk factors in HIV infection
AIDS Res Hum Retroviruses, 30 (6), 514-22
DOI 10.1089/aid.2013.0280, PubMed 24521167

Trøseid M, Ueland T, Hov JR, Svardal A, Gregersen I, Dahl CP, Aakhus S, Gude E, Bjørndal B, Halvorsen B, Karlsen TH, Aukrust P, Gullestad L, Berge RK, Yndestad A (2014)
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
J Intern Med, 277 (6), 717-26
DOI 10.1111/joim.12328, PubMed 25382824

Publications 2013

Feruglio SL, Trøseid M, Damås JK, Kvale D, Dyrhol-Riise AM (2013)
Soluble markers of the Toll-like receptor 4 pathway differentiate between active and latent tuberculosis and are associated with treatment responses
PLoS One, 8 (7), e69896
DOI 10.1371/journal.pone.0069896, PubMed 23875007

Haugaard AK, Lund TT, Birch C, Rönsholt F, Trøseid M, Ullum H, Gerstoft J, Johansson PI, Nielsen SD, Ostrowski SR (2013)
Discrepant coagulation profile in HIV infection: elevated D-dimer but impaired platelet aggregation and clot initiation
AIDS, 27 (17), 2749-58
DOI 10.1097/01.aids.0000432462.21723.ed, PubMed 23842126

Manner IW, Baekken M, Kvale D, Oektedalen O, Pedersen M, Nielsen SD, Nowak P, Os I, Trøseid M (2013)
Markers of microbial translocation predict hypertension in HIV-infected individuals
HIV Med, 14 (6), 354-61
DOI 10.1111/hiv.12015, PubMed 23332095

Pedersen KK, Pedersen M, Trøseid M, Gaardbo JC, Lund TT, Thomsen C, Gerstoft J, Kvale D, Nielsen SD (2013)
Microbial translocation in HIV infection is associated with dyslipidemia, insulin resistance, and risk of myocardial infarction
J Acquir Immune Defic Syndr, 64 (5), 425-33
DOI 10.1097/QAI.0b013e31829f919d, PubMed 23797689

Trøseid M, Nestvold TK, Rudi K, Thoresen H, Nielsen EW, Lappegård KT (2013)
Plasma lipopolysaccharide is closely associated with glycemic control and abdominal obesity: evidence from bariatric surgery
Diabetes Care, 36 (11), 3627-32
DOI 10.2337/dc13-0451, PubMed 23835694

Publications 2012

Manner IW, Trøseid M, Oektedalen O, Baekken M, Os I (2012)
Low nadir CD4 cell count predicts sustained hypertension in HIV-infected individuals
J Clin Hypertens (Greenwich), 15 (2), 101-6
DOI 10.1111/jch.12029, PubMed 23339727

Nowak P, Abdurahman S, Lindkvist A, Troseid M, Sönnerborg A (2012)
Impact of HMGB1/TLR Ligand Complexes on HIV-1 Replication: Possible Role for Flagellin during HIV-1 Infection
Int J Microbiol, 2012, 263836
DOI 10.1155/2012/263836, PubMed 22719767

Nowak P, Nystrom J, Troseid M (2012)
High levels of HMGB1 in plasma may be due to ex vivo cell necrosis
Anticancer Res, 32 (9), 4067-9
PubMed 22993362

Trøseid M, Lind A, Nowak P, Barqasho B, Heger B, Lygren I, Pedersen KK, Kanda T, Funaoka H, Damås JK, Kvale D (2012)
Circulating levels of HMGB1 are correlated strongly with MD2 in HIV-infection: possible implication for TLR4-signalling and chronic immune activation
Innate Immun, 19 (3), 290-7
DOI 10.1177/1753425912461042, PubMed 23070967

Publications 2011

Kivuyo SL, Johannessen A, Trøseid M, Kasubi MJ, Gundersen SG, Naman E, Mushi D, Ngowi BJ, Mfinanga GS, Bruun JN (2011)
p24 antigen detection on dried blood spots is a feasible and reliable test for infant HIV infection in rural Tanzania
Int J STD AIDS, 22 (12), 719-21
DOI 10.1258/ijsa.2009.009382, PubMed 22174052

Trøseid M (2011)
[The fight against HIV--two scenarios]
Tidsskr Nor Laegeforen, 131 (23), 2331
DOI 10.4045/tidsskr.11.1213, PubMed 22139097

Trøseid M, Sönnerborg A, Nowak P (2011)
High mobility group box protein-1 in HIV-1 infection
Curr HIV Res, 9 (1), 6-10
DOI 10.2174/157016211794582632, PubMed 21198433

Weiss TW, Arnesen H, Trøseid M, Kaun C, Hjerkinn EM, Huber K, Wojta J, Seljeflot I (2011)
Adipose tissue expression of interleukin-18 mRNA is elevated in subjects with metabolic syndrome and independently associated with fasting glucose
Wien Klin Wochenschr, 123 (21-22), 650-4
DOI 10.1007/s00508-011-0028-6, PubMed 21842238

Publications 2010

Trøseid M (2010)
Studies on inflammation and atherosclerosis in the metabolic syndrome
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 920, 1 b. (flere pag.)
BIBSYS 100892027, ISBN 978-82-8072-581-3

Trøseid M, Johannessen A (2010)
[The battle against HIV can be won, but there is not enough money!]
Tidsskr Nor Laegeforen, 130 (16), 1599-600
DOI 10.4045/tidsskr.10.0705, PubMed 20805855

Trøseid M, Johannessen A (2010)
[A step in the right direction]
Tidsskr Nor Laegeforen, 130 (22), 2223
DOI 10.4045/tidsskr.10.1100, PubMed 21109841

Trøseid M, Nowak P, Nyström J, Lindkvist A, Abdurahman S, Sönnerborg A (2010)
Elevated plasma levels of lipopolysaccharide and high mobility group box-1 protein are associated with high viral load in HIV-1 infection: reduction by 2-year antiretroviral therapy
AIDS, 24 (11), 1733-7
DOI 10.1097/QAD.0b013e32833b254d, PubMed 20502315

Trøseid M, Seljeflot I, Arnesen H (2010)
The role of interleukin-18 in the metabolic syndrome
Cardiovasc Diabetol, 9, 11
DOI 10.1186/1475-2840-9-11, PubMed 20331890

Weiss TW, Furenes EB, Trøseid M, Solheim S, Hjerkinn EM, Seljeflot I, Arnesen H (2010)
Prediction of cardiovascular events by matrix metalloproteinase (MMP)-9 in elderly men
Thromb Haemost, 103 (3), 679-81
DOI 10.1160/TH09-05-0317, PubMed 20076844

Weiss TW, Schumacher S, Kaun C, Katsaros KM, Trøseid M, Huber K, Maurer G, Wojta J (2010)
Association between smoking and presence of mycoplasma pneumoniae in circulating leukocytes
Swiss Med Wkly, 140, w13105
DOI 10.4414/smw.2010.13105, PubMed 20927683

Publications 2009

Johannessen A, Trøseid M, Calmy A (2009)
Dried blood spots can expand access to virological monitoring of HIV treatment in resource-limited settings
J Antimicrob Chemother, 64 (6), 1126-9
DOI 10.1093/jac/dkp353, PubMed 19776036

Trøseid M, Arnesen H, Hjerkinn EM, Seljeflot I (2009)
Serum levels of interleukin-18 are reduced by diet and n-3 fatty acid intervention in elderly high-risk men
Metabolism, 58 (11), 1543-9
DOI 10.1016/j.metabol.2009.04.031, PubMed 19595382

Trøseid M, Eskesen A, Bruun JN (2009)
[Immune reconstitution inflammatory syndrome and treatment of HIV infection]
Tidsskr Nor Laegeforen, 129 (23), 2484-7
DOI 10.4045/tidsskr.09.0190, PubMed 19997137

Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2009)
The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome
Metab Syndr Relat Disord, 7 (6), 579-84
DOI 10.1089/met.2009.0003, PubMed 19900154

Trøseid M, Seljeflot I, Weiss TW, Klemsdal TO, Hjerkinn EM, Arnesen H (2009)
Arterial stiffness is independently associated with interleukin-18 and components of the metabolic syndrome
Atherosclerosis, 209 (2), 337-9
DOI 10.1016/j.atherosclerosis.2009.09.028, PubMed 19836750

Publications 2008

Trøseid M (2008)
[Children with HIV--still a big challenge]
Tidsskr Nor Laegeforen, 128 (8), 952-3
PubMed 18459190

Trøseid M, Seljeflot I, Hjerkinn EM, Arnesen H (2008)
Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia
Diabetes Care, 32 (3), 486-92
DOI 10.2337/dc08-1710, PubMed 19092166

Trøseid M, Steinbakk M (2008)
[Whooping cough vaccination should be re-evaluated]
Tidsskr Nor Laegeforen, 128 (2), 204
PubMed 18202739

Publications 2007

Trøseid M, Handal N, Holen Ø (2007)
[Tuberculosis--the forgotten part of the HIV epidemic]
Tidsskr Nor Laegeforen, 127 (20), 2712-4
PubMed 17952165

Publications 2006

Dudman SG, Trøseid M, Jonassen TØ, Steinbakk M (2006)
[Whooping cough--an increasing problem in Norway]
Tidsskr Nor Laegeforen, 126 (3), 305-8
PubMed 16440035

Trøseid M (2006)
[Antiretroviral therapy in Poipet]
Tidsskr Nor Laegeforen, 126 (17), 2290-2
PubMed 16967084

Trøseid M, Hjerkinn EM, Seljeflot I, Klemsdal TO, Bergengen L, Breivik L, Arnesen H (2006)
Comparison of biochemical, functional and structural aspects of arterial wall properties in elderly men
Scand J Clin Lab Invest, 66 (2), 137-45
DOI 10.1080/00365510500474462, PubMed 16537247

Publications 2005

Trøseid M, Henriksen OA, Lindal S (2005)
Statin-associated myopathy with normal creatine kinase levels. Case report from a Norwegian family
APMIS, 113 (9), 635-7
DOI 10.1111/j.1600-0463.2005.apm_270.x, PubMed 16218940

Trøseid M, Jonassen TØ, Steinbakk M (2005)
Isolation of Bordetella pertussis in blood culture from a patient with multiple myeloma
J Infect, 52 (1), e11-3
DOI 10.1016/j.jinf.2005.04.014, PubMed 15936087

Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2005)
Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome
Scand J Clin Lab Invest, 65 (4), 283-90
DOI 10.1080/00365510510013811, PubMed 16076683

Publications 2004

Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE (2004)
Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome
Eur Heart J, 25 (4), 349-55
DOI 10.1016/j.ehj.2003.12.006, PubMed 14984925

Publications 2002

Trøseid M (2002)
[Reduced use of restricted-prescription preparations in general practice]
Tidsskr Nor Laegeforen, 122 (5), 482-3
PubMed 11961975

Publications 1999

Trøseid M, Gerlyng P (1999)
[Parvovirus B19 as a cause of acute arthritis]
Tidsskr Nor Laegeforen, 119 (23), 3415-6
PubMed 10553337

Publications 1997

Sømme S, Trøseid M (1997)
[Being a medical student in Michigan]
Tidsskr Nor Laegeforen, 117 (19), 2828-9
PubMed 9312879