Marius Trøseid
- Group leader, ass. professor; MD, PhD
- +47 23 07 18 98
Publications 2024
Pulmonary comorbidities in people with HIV- the microbiome connection
Curr Opin HIV AIDS, 19 (5), 246-252
DOI 10.1097/COH.0000000000000871, PubMed 38935049
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241
Gut dysbiosis and neutrophil extracellular traps in chronic heart failure
Int J Cardiol, 419, 132689 (in press)
DOI 10.1016/j.ijcard.2024.132689, PubMed 39489348
Diagnostics, treatment and outcomes of cardiac sarcoidosis in a Norwegian cohort
Int J Cardiol, 400, 131809
DOI 10.1016/j.ijcard.2024.131809, PubMed 38272129
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108
Tixagevimab-cilgavimab (AZD7442) for the treatment of patients hospitalized with COVID-19 (DisCoVeRy): A phase 3, randomized, double-blind, placebo-controlled trial
J Infect, 88 (3), 106120
DOI 10.1016/j.jinf.2024.106120, PubMed 38367705
Chronic HIV Infection Increases Monocyte NLRP3 Inflammasome-Dependent IL-1α and IL-1β Release
Int J Mol Sci, 25 (13)
DOI 10.3390/ijms25137141, PubMed 39000248
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465
Intestinal fatty acid binding protein is associated with infarct size and cardiac function in acute heart failure following myocardial infarction
Open Heart, 11 (2)
DOI 10.1136/openhrt-2024-002868, PubMed 39277188
The effects of remdesivir on long-term symptoms in patients hospitalised for COVID-19: a pre-specified exploratory analysis
Commun Med (Lond), 4 (1), 231
DOI 10.1038/s43856-024-00650-4, PubMed 39533001
Experiences and challenges with the new European Clinical Trials Regulation
Trials, 25 (1), 3
DOI 10.1186/s13063-023-07869-x, PubMed 38167484
Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
Genome Med, 16 (1), 27
DOI 10.1186/s13073-024-01296-6, PubMed 38331891
Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
Nat Med, 30 (1), 303
DOI 10.1038/s41591-023-02529-8, PubMed 37587221
Viral, Host Factors or Both as COVID-19 Biomarkers
Clin Infect Dis, 78 (6), 1504-1505
DOI 10.1093/cid/ciad779, PubMed 38376208
Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV
J Infect Dis, 229 (3), 898-907
DOI 10.1093/infdis/jiad604, PubMed 38195204
Gut microbiome and cardiometabolic comorbidities in people living with HIV
Microbiome, 12 (1), 106
DOI 10.1186/s40168-024-01815-y, PubMed 38877521
Markers of extracellular matrix degradation and inflammasome activation are associated with carotid plaques in virally suppressed people with HIV in Botswana
AIDS (in press)
DOI 10.1097/QAD.0000000000004014, PubMed 39283741
High viral loads combined with inflammatory markers predict disease severity in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 296 (3), 249-259
DOI 10.1111/joim.13820, PubMed 39011800
Publications 2023
Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
J Hepatol, 79 (4), 955-966
DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069
[Gut microbiota and intestinal disease –a sober warning]
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.23.0121, PubMed 37376933
Clonal hematopoiesis of indeterminate potential in persons with HIV
AIDS, 38 (4), 487-495
DOI 10.1097/QAD.0000000000003788, PubMed 37976039
Coronary Artery Disease in Persons With Human Immunodeficiency Virus Without Detectable Viral Replication
Open Forum Infect Dis, 10 (7), ofad298
DOI 10.1093/ofid/ofad298, PubMed 37441354
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Elife, 12
DOI 10.7554/eLife.82785, PubMed 36794912
Editorial: Targeting the microbiota to attenuate chronic inflammation
Front Immunol, 14, 1202222
DOI 10.3389/fimmu.2023.1202222, PubMed 37153550
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572
Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
Front Cardiovasc Med, 10, 1160030
DOI 10.3389/fcvm.2023.1160030, PubMed 37332580
Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
Nat Med, 29 (7), 1738-1749
DOI 10.1038/s41591-023-02407-3, PubMed 37464040
Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia
Br J Clin Pharmacol, 89 (4), 1318-1328
DOI 10.1111/bcp.15669, PubMed 36680782
Elevated Levels of Interleukin-1β and Interleukin-10 Are Associated With Faster Lung Function Decline in People With Well-Treated Human Immunodeficiency Virus
J Infect Dis, 228 (8), 1080-1088
DOI 10.1093/infdis/jiad233, PubMed 37366576
Which trial do we need? Management of elderly, fragile, fully vaccinated patients hospitalized for SARS-CoV-2 infection
Clin Microbiol Infect, 29 (4), 419-421
DOI 10.1016/j.cmi.2023.01.006, PubMed 36641054
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
Crit Care, 27 (1), 69
DOI 10.1186/s13054-023-04356-2, PubMed 36814280
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350
Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression
Viruses, 15 (7)
DOI 10.3390/v15071613, PubMed 37515299
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413
Publications 2022
Gut Leakage and Cardiac Biomarkers after Prolonged Strenuous Exercise
Med Sci Sports Exerc, 54 (9), 1476-1482
DOI 10.1249/MSS.0000000000002948, PubMed 35482788
Phenylacetylglutamine From the Gut Microbiota: A Future Therapeutic Target in Heart Failure?
Circ Heart Fail, 16 (1), e010222
DOI 10.1161/CIRCHEARTFAILURE.122.010222, PubMed 36524473
Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
J Infect Dis, 225 (11), 1948-1954
DOI 10.1093/infdis/jiac018, PubMed 35089326
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188
Rethinking treatment paradigms for the deployment of SARS-CoV-2 antiviral drugs on the shifting landscape of new variants
Front Microbiol, 13, 998287
DOI 10.3389/fmicb.2022.998287, PubMed 36312942
Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls
BMC Infect Dis, 22 (1), 451
DOI 10.1186/s12879-022-07450-y, PubMed 35546661
Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
J Infect Dis, 225 (4), 661-674
DOI 10.1093/infdis/jiaa714, PubMed 33216130
Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
J Acquir Immune Defic Syndr, 89 (1), 77-86
DOI 10.1097/QAI.0000000000002817, PubMed 34878437
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611
Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
Scand J Clin Lab Invest, 82 (5), 363-370
DOI 10.1080/00365513.2022.2102540, PubMed 35913798
Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
Sci Rep, 12 (1), 22378
DOI 10.1038/s41598-022-26759-x, PubMed 36572703
High incidence of subclinical peripheral artery disease in people with HIV
AIDS, 36 (10), 1355-1362
DOI 10.1097/QAD.0000000000003252, PubMed 35608109
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589
Accelerating clinical trial implementation in the context of the COVID-19 pandemic: author's response
Clin Microbiol Infect, 28 (5), 743-744
DOI 10.1016/j.cmi.2021.12.014, PubMed 35031489
Immunocompromised patients have been neglected in COVID-19 trials: a call for action
Clin Microbiol Infect, 28 (9), 1182-1183
DOI 10.1016/j.cmi.2022.05.005, PubMed 35623577
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
DOI 10.1093/infdis/jiac313, PubMed 35876699
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063
Publications 2021
Gut related inflammation and cardiorespiratory fitness in patients with CAD and type 2 diabetes: a sub-study of a randomized controlled trial on exercise training
Diabetol Metab Syndr, 13 (1), 36
DOI 10.1186/s13098-021-00655-2, PubMed 33794977
Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease
Cells, 10 (9)
DOI 10.3390/cells10092193, PubMed 34571843
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol, 56 (4), 443-452
DOI 10.1080/00365521.2021.1880627, PubMed 33583308
Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV
J Acquir Immune Defic Syndr, 87 (2), e177-e181
DOI 10.1097/QAI.0000000000002664, PubMed 33633032
Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group
Clin Microbiol Infect, 28 (1), 1-5
DOI 10.1016/j.cmi.2021.10.011, PubMed 34763056
Real-World Experiences With Facilitated Subcutaneous Immunoglobulin Substitution in Patients With Hypogammaglobulinemia, Using a Three-Step Ramp-Up Schedule
Front Immunol, 12, 670547
DOI 10.3389/fimmu.2021.670547, PubMed 34012453
Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections
Viruses, 13 (12)
DOI 10.3390/v13122489, PubMed 34960758
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380
Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
Sci Rep, 11 (1), 11593
DOI 10.1038/s41598-021-90976-z, PubMed 34078971
Independent Association of Interleukin 6 With Low Dynamic Lung Function and Airflow Limitation in Well-Treated People With Human Immunodeficiency Virus
J Infect Dis, 223 (10), 1690-1698
DOI 10.1093/infdis/jiaa600, PubMed 33141877
Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV
Front Immunol, 12, 668113
DOI 10.3389/fimmu.2021.668113, PubMed 33936110
Assessing the evidence on remdesivir
Lancet Infect Dis, 21 (12), 1630-1631
DOI 10.1016/S1473-3099(21)00695-2, PubMed 34838222
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007
Publications 2020
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus
J Infect Dis, 221 (3), 419-427
DOI 10.1093/infdis/jiz465, PubMed 31538186
Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
Clin Infect Dis, 71 (8), e359-e367
DOI 10.1093/cid/ciz1235, PubMed 31894240
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med, 289 (4), 523-531
DOI 10.1111/joim.13178, PubMed 32976665
Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection
Open Forum Infect Dis, 7 (2), ofaa033
DOI 10.1093/ofid/ofaa033, PubMed 32055642
Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals
J Infect Dis, 221 (4), 506-509
DOI 10.1093/infdis/jiz253, PubMed 31077280
No evidence of a synergistic effect of HIV infection and diabetes mellitus type 2 on fat distribution, plasma adiponectin or inflammatory markers
BMC Infect Dis, 20 (1), 882
DOI 10.1186/s12879-020-05594-3, PubMed 33238950
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138
Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
Gastroenterology, 160 (5), 1784-1798.e0
DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail, 7 (2), 456-466
DOI 10.1002/ehf2.12596, PubMed 31978943
[Elevated serum ferritin is not only a sign of liver failure]
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0376, PubMed 32463199
Probiotics to manage inflammation in HIV infection
Curr Opin Infect Dis, 33 (1), 34-43
DOI 10.1097/QCO.0000000000000612, PubMed 31789692
[When COVID-19 meets the African health service]
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0283, PubMed 32378852
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353
[Experimental treatment for COVID-19 should be undertaken in randomised studies]
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0282, PubMed 32378863
Publications 2019
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568
Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
ESC Heart Fail, 6 (3), 557-558
DOI 10.1002/ehf2.12437, PubMed 31034162
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315
Bone Marrow Transplantation - a cure for HIV?
Tidsskr. Nor. Laegeforen., 139 (7), 580
[Bone marrow transplantation – a cure for HIV?]
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0199, PubMed 30969050
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J Heart Lung Transplant, 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003, PubMed 31301965
Publications 2018
Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
J Acquir Immune Defic Syndr, 78 (4), 450-457
DOI 10.1097/QAI.0000000000001693, PubMed 29874201
Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study
Diabetol Metab Syndr, 10, 59
DOI 10.1186/s13098-018-0360-3, PubMed 30038669
Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
Liver Int, 39 (2), 371-381
DOI 10.1111/liv.13979, PubMed 30269440
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
Sci Rep, 8 (1), 6725
DOI 10.1038/s41598-018-25168-3, PubMed 29712976
Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
J Am Coll Cardiol, 71 (10), 1184-1186
DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360
Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial
ESC Heart Fail, 5 (5), 977-984
DOI 10.1002/ehf2.12332, PubMed 30088346
The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages
AIDS, 32 (12), 1589-1598
DOI 10.1097/QAD.0000000000001813, PubMed 29620717
Tenders for HIV medicines are not academically justified
Tidsskr. Nor. Laegeforen., 138 (20), 1912-1913
[Tendering for HIV drugs is not clinically justified]
Tidsskr Nor Laegeforen, 138 (20)
DOI 10.4045/tidsskr.18.0808, PubMed 30539614
Publications 2017
Tryptophan catabolism and immune activation in primary and chronic HIV infection
BMC Infect Dis, 17 (1), 349
DOI 10.1186/s12879-017-2456-z, PubMed 28511640
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
BMC Infect Dis, 17 (1), 445
DOI 10.1186/s12879-017-2547-x, PubMed 28645263
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation
BMC Infect Dis, 17 (1), 234
DOI 10.1186/s12879-017-2334-8, PubMed 28356058
Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals
Scand J Clin Lab Invest, 77 (8), 628-633
DOI 10.1080/00365513.2017.1393691, PubMed 29069988
Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
J Card Fail, 23 (9), 666-671
DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
PLoS One, 12 (5), e0176527
DOI 10.1371/journal.pone.0176527, PubMed 28464042
Gut microbiota and acute coronary syndromes: ready for use in the emergency room?
Eur Heart J, 38 (11), 825-827
DOI 10.1093/eurheartj/ehx005, PubMed 28159962
Publications 2016
Marker of Endothelial Dysfunction Asymmetric Dimethylarginine Is Elevated in HIV Infection but Not Associated With Subclinical Atherosclerosis
J Acquir Immune Defic Syndr, 73 (5), 507-513
DOI 10.1097/QAI.0000000000001148, PubMed 27509250
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection
J Acquir Immune Defic Syndr, 71 (2), 130-6
DOI 10.1097/QAI.0000000000000843, PubMed 26413854
Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study
BMC Infect Dis, 16, 176
DOI 10.1186/s12879-016-1510-6, PubMed 27103116
[A man in his 20s with abdominal pain and heart murmurs]
Tidsskr Nor Laegeforen, 136 (3), 238-40
DOI 10.4045/tidsskr.15.0790, PubMed 26860384
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
Mucosal Immunol, 9 (6), 1455-1465
DOI 10.1038/mi.2016.18, PubMed 26982597
Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT
J Acquir Immune Defic Syndr, 72 (4), e83-5
DOI 10.1097/QAI.0000000000001044, PubMed 27152465
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816
Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
United European Gastroenterol J, 5 (4), 532-541
DOI 10.1177/2050640616663453, PubMed 28588885
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
Atherosclerosis, 247, 64-9
DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
J Acquir Immune Defic Syndr, 73 (2), 138-48
DOI 10.1097/QAI.0000000000001080, PubMed 27632144
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
Metab Syndr Relat Disord, 14 (4), 197-201
DOI 10.1089/met.2015.0120, PubMed 27081744
Publications 2015
T-cell homeostasis in chronic HCV-infected patients treated with interferon and ribavirin or an interferon-free regimen
APMIS, 123 (10), 903-11
DOI 10.1111/apm.12429, PubMed 26279289
Personalised medicine targeting the gut microbiota?
Tidsskr Nor Laegeforen, 135 (7), 624
DOI 10.4045/tidsskr.14.1431, PubMed 25899345
Personalized intestinal flora medicine?
Tidsskr. Nor. Laegeforen., 135 (7), 624
Gut microbiota diversity predicts immune status in HIV-1 infection
AIDS, 29 (18), 2409-18
DOI 10.1097/QAD.0000000000000869, PubMed 26355675
Lower Self-Reported Quality of Life in HIV-Infected Patients on cART and With Low Comorbidity Compared With Healthy Controls
J Acquir Immune Defic Syndr, 70 (1), 16-22
DOI 10.1097/QAI.0000000000000697, PubMed 26017659
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571
[Antiretroviral drugs against HIV infections]
Tidsskr Nor Laegeforen, 135 (11), 1054
DOI 10.4045/tidsskr.15.0156, PubMed 26080783
AIDS epidemic Defeats, victories and new challenges
Tidsskr. Nor. Laegeforen., 135 (11), 1059
DOI 10.4045/tidsskr.15.0533
Soluble CD14 is associated with markers of vascular dysfunction in bariatric surgery patients
Metab Syndr Relat Disord, 13 (3), 119-24
DOI 10.1089/met.2014.0111, PubMed 25562385
Publications 2014
A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers
PLoS One, 9 (1), e85604
DOI 10.1371/journal.pone.0085604, PubMed 24416431
Plasma lipopolysaccharide and triglycerides are independently associated and both markers correlate with the development of metabolic syndrome in HIV infection
J Acquir Immune Defic Syndr, 65 (4), e158-61
DOI 10.1097/QAI.0000000000000055, PubMed 24577189
Monocyte activation, but not microbial translocation, is independently associated with markers of endovascular dysfunction in HIV-infected patients receiving cART
J Acquir Immune Defic Syndr, 67 (4), 370-4
DOI 10.1097/QAI.0000000000000339, PubMed 25226210
Antiretroviral treatment failure predicts mortality in rural Tanzania
Int J STD AIDS, 26 (9), 633-9
DOI 10.1177/0956462414548460, PubMed 25122578
Reduced trunk fat and triglycerides after strength training are associated with reduced LPS levels in HIV-infected individuals
J Acquir Immune Defic Syndr, 66 (2), e52-4
DOI 10.1097/QAI.0000000000000132, PubMed 24608893
Microbial translocation and cardiometabolic risk factors in HIV infection
AIDS Res Hum Retroviruses, 30 (6), 514-22
DOI 10.1089/aid.2013.0280, PubMed 24521167
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure
J Intern Med, 277 (6), 717-26
DOI 10.1111/joim.12328, PubMed 25382824
Publications 2013
Soluble markers of the Toll-like receptor 4 pathway differentiate between active and latent tuberculosis and are associated with treatment responses
PLoS One, 8 (7), e69896
DOI 10.1371/journal.pone.0069896, PubMed 23875007
Discrepant coagulation profile in HIV infection: elevated D-dimer but impaired platelet aggregation and clot initiation
AIDS, 27 (17), 2749-58
DOI 10.1097/01.aids.0000432462.21723.ed, PubMed 23842126
Markers of microbial translocation predict hypertension in HIV-infected individuals
HIV Med, 14 (6), 354-61
DOI 10.1111/hiv.12015, PubMed 23332095
Microbial translocation in HIV infection is associated with dyslipidemia, insulin resistance, and risk of myocardial infarction
J Acquir Immune Defic Syndr, 64 (5), 425-33
DOI 10.1097/QAI.0b013e31829f919d, PubMed 23797689
Plasma lipopolysaccharide is closely associated with glycemic control and abdominal obesity: evidence from bariatric surgery
Diabetes Care, 36 (11), 3627-32
DOI 10.2337/dc13-0451, PubMed 23835694
Publications 2012
Low nadir CD4 cell count predicts sustained hypertension in HIV-infected individuals
J Clin Hypertens (Greenwich), 15 (2), 101-6
DOI 10.1111/jch.12029, PubMed 23339727
Impact of HMGB1/TLR Ligand Complexes on HIV-1 Replication: Possible Role for Flagellin during HIV-1 Infection
Int J Microbiol, 2012, 263836
DOI 10.1155/2012/263836, PubMed 22719767
High levels of HMGB1 in plasma may be due to ex vivo cell necrosis
Anticancer Res, 32 (9), 4067-9
PubMed 22993362
Circulating levels of HMGB1 are correlated strongly with MD2 in HIV-infection: possible implication for TLR4-signalling and chronic immune activation
Innate Immun, 19 (3), 290-7
DOI 10.1177/1753425912461042, PubMed 23070967
Publications 2011
p24 antigen detection on dried blood spots is a feasible and reliable test for infant HIV infection in rural Tanzania
Int J STD AIDS, 22 (12), 719-21
DOI 10.1258/ijsa.2009.009382, PubMed 22174052
[The fight against HIV--two scenarios]
Tidsskr Nor Laegeforen, 131 (23), 2331
DOI 10.4045/tidsskr.11.1213, PubMed 22139097
High mobility group box protein-1 in HIV-1 infection
Curr HIV Res, 9 (1), 6-10
DOI 10.2174/157016211794582632, PubMed 21198433
Adipose tissue expression of interleukin-18 mRNA is elevated in subjects with metabolic syndrome and independently associated with fasting glucose
Wien Klin Wochenschr, 123 (21-22), 650-4
DOI 10.1007/s00508-011-0028-6, PubMed 21842238
Publications 2010
Studies on inflammation and atherosclerosis in the metabolic syndrome
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 920, 1 b. (flere pag.)
BIBSYS 100892027, ISBN 978-82-8072-581-3
[The battle against HIV can be won, but there is not enough money!]
Tidsskr Nor Laegeforen, 130 (16), 1599-600
DOI 10.4045/tidsskr.10.0705, PubMed 20805855
[A step in the right direction]
Tidsskr Nor Laegeforen, 130 (22), 2223
DOI 10.4045/tidsskr.10.1100, PubMed 21109841
Elevated plasma levels of lipopolysaccharide and high mobility group box-1 protein are associated with high viral load in HIV-1 infection: reduction by 2-year antiretroviral therapy
AIDS, 24 (11), 1733-7
DOI 10.1097/QAD.0b013e32833b254d, PubMed 20502315
The role of interleukin-18 in the metabolic syndrome
Cardiovasc Diabetol, 9, 11
DOI 10.1186/1475-2840-9-11, PubMed 20331890
Prediction of cardiovascular events by matrix metalloproteinase (MMP)-9 in elderly men
Thromb Haemost, 103 (3), 679-81
DOI 10.1160/TH09-05-0317, PubMed 20076844
Association between smoking and presence of mycoplasma pneumoniae in circulating leukocytes
Swiss Med Wkly, 140, w13105
DOI 10.4414/smw.2010.13105, PubMed 20927683
Publications 2009
Dried blood spots can expand access to virological monitoring of HIV treatment in resource-limited settings
J Antimicrob Chemother, 64 (6), 1126-9
DOI 10.1093/jac/dkp353, PubMed 19776036
Serum levels of interleukin-18 are reduced by diet and n-3 fatty acid intervention in elderly high-risk men
Metabolism, 58 (11), 1543-9
DOI 10.1016/j.metabol.2009.04.031, PubMed 19595382
[Immune reconstitution inflammatory syndrome and treatment of HIV infection]
Tidsskr Nor Laegeforen, 129 (23), 2484-7
DOI 10.4045/tidsskr.09.0190, PubMed 19997137
The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome
Metab Syndr Relat Disord, 7 (6), 579-84
DOI 10.1089/met.2009.0003, PubMed 19900154
Arterial stiffness is independently associated with interleukin-18 and components of the metabolic syndrome
Atherosclerosis, 209 (2), 337-9
DOI 10.1016/j.atherosclerosis.2009.09.028, PubMed 19836750
Publications 2008
[Children with HIV--still a big challenge]
Tidsskr Nor Laegeforen, 128 (8), 952-3
PubMed 18459190
Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia
Diabetes Care, 32 (3), 486-92
DOI 10.2337/dc08-1710, PubMed 19092166
[Whooping cough vaccination should be re-evaluated]
Tidsskr Nor Laegeforen, 128 (2), 204
PubMed 18202739
Publications 2007
[Tuberculosis--the forgotten part of the HIV epidemic]
Tidsskr Nor Laegeforen, 127 (20), 2712-4
PubMed 17952165
Publications 2006
[Whooping cough--an increasing problem in Norway]
Tidsskr Nor Laegeforen, 126 (3), 305-8
PubMed 16440035
[Antiretroviral therapy in Poipet]
Tidsskr Nor Laegeforen, 126 (17), 2290-2
PubMed 16967084
Comparison of biochemical, functional and structural aspects of arterial wall properties in elderly men
Scand J Clin Lab Invest, 66 (2), 137-45
DOI 10.1080/00365510500474462, PubMed 16537247
Publications 2005
Statin-associated myopathy with normal creatine kinase levels. Case report from a Norwegian family
APMIS, 113 (9), 635-7
DOI 10.1111/j.1600-0463.2005.apm_270.x, PubMed 16218940
Isolation of Bordetella pertussis in blood culture from a patient with multiple myeloma
J Infect, 52 (1), e11-3
DOI 10.1016/j.jinf.2005.04.014, PubMed 15936087
Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome
Scand J Clin Lab Invest, 65 (4), 283-90
DOI 10.1080/00365510510013811, PubMed 16076683
Publications 2004
Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome
Eur Heart J, 25 (4), 349-55
DOI 10.1016/j.ehj.2003.12.006, PubMed 14984925
Publications 2002
[Reduced use of restricted-prescription preparations in general practice]
Tidsskr Nor Laegeforen, 122 (5), 482-3
PubMed 11961975
Publications 1999
[Parvovirus B19 as a cause of acute arthritis]
Tidsskr Nor Laegeforen, 119 (23), 3415-6
PubMed 10553337
Publications 1997
[Being a medical student in Michigan]
Tidsskr Nor Laegeforen, 117 (19), 2828-9
PubMed 9312879