Pierre Chymkowitch

  • Project Group Leader; PhD
  • +47 916 31 231

Curriculum Vitae (open as PDF)

 

Publications 2019

Nguéa P A, Robertson J, Herrera MC, Chymkowitch P, Enserink JM (2019)
Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
J Biol Chem, 294 (49), 18784-18795
DOI 10.1074/jbc.RA119.009721, PubMed 31676685

Publications 2018

Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619

Herrera MC, Chymkowitch P, Robertson JM, Eriksson J, Bøe SO, Alseth I, Enserink JM (2018)
Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 12188-12189
DOI 10.1093/nar/gky1102, PubMed 30395271

Kruitwagen T, Chymkowitch P, Denoth-Lippuner A, Enserink J, Barral Y (2018)
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
Cell, 175 (3), 780-795.e15
DOI 10.1016/j.cell.2018.09.012, PubMed 30318142

Publications 2017

Chymkowitch P, Enserink JM (2017)
Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063

Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404

Chymkowitch P, P AN, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM (2017)
Corrigendum: Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 27 (2), 334
DOI 10.1101/gr.218370.116, PubMed 28148563

Enserink J, Nguéa P A, Chymkowitch P (2017)
Anabolic transcription: Secrets of the sumo diet
Cell Cycle, 16 (7), 593-594
DOI 10.1080/15384101.2017.1294945, PubMed 28278057

Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM (2017)
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
G3 (Bethesda), 7 (6), 1753-1766
DOI 10.1534/g3.117.042317, PubMed 28428242

Zimmermann C, Santos A, Gable K, Epstein S, Gururaj C, Chymkowitch P, Pultz D, Rødkær SV, Clay L, Bjørås M, Barral Y, Chang A, Færgeman NJ, Dunn TM, Riezman H, Enserink JM (2017)
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy
Cell Rep, 18 (8), 2073-2074
DOI 10.1016/j.celrep.2017.02.020, PubMed 28228270

Publications 2015

Chymkowitch P, Nguéa P A, Enserink JM (2015)
SUMO-regulated transcription: challenging the dogma
Bioessays, 37 (10), 1095-105
DOI 10.1002/bies.201500065, PubMed 26354225

Chymkowitch P, Nguéa AP, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM (2015)
Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 25 (6), 897-906
DOI 10.1101/gr.185793.114, PubMed 25800674

Publications 2013

Zimmermann C, Santos A, Gable K, Epstein S, Gururaj C, Chymkowitch P, Pultz D, Rødkær SV, Clay L, Bjørås M, Barral Y, Chang A, Færgeman NJ, Dunn TM, Riezman H, Enserink JM (2013)
TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
Cell Rep, 5 (4), 1036-46
DOI 10.1016/j.celrep.2013.10.024, PubMed 24239358

Publications 2012

Chymkowitch P, Eldholm V, Lorenz S, Zimmermann C, Lindvall JM, Bjørås M, Meza-Zepeda LA, Enserink JM (2012)
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
Proc Natl Acad Sci U S A, 109 (26), 10450-5
DOI 10.1073/pnas.1200067109, PubMed 22689984

Chymkowitch P, Enserink JM (2012)
The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK
Transcription, 4 (1), 3-6
DOI 10.4161/trns.22456, PubMed 23131667

Publications 2011

Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM (2011)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
Proc Natl Acad Sci U S A, 108 (46), 18748-53
DOI 10.1073/pnas.1115885108, PubMed 22042866

Publications 2010

Chymkowitch P, Le May N, Charneau P, Compe E, Egly JM (2010)
The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process
EMBO J, 30 (3), 468-79
DOI 10.1038/emboj.2010.337, PubMed 21157430

Publications 2007

Ito S, Kuraoka I, Chymkowitch P, Compe E, Takedachi A, Ishigami C, Coin F, Egly JM, Tanaka K (2007)
XPG stabilizes TFIIH, allowing transactivation of nuclear receptors: implications for Cockayne syndrome in XP-G/CS patients
Mol Cell, 26 (2), 231-43
DOI 10.1016/j.molcel.2007.03.013, PubMed 17466625

Publications 2004

Drané P, Compe E, Catez P, Chymkowitch P, Egly JM (2004)
Selective regulation of vitamin D receptor-responsive genes by TFIIH
Mol Cell, 16 (2), 187-97
DOI 10.1016/j.molcel.2004.10.007, PubMed 15494306

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