Aleksander Rygh Holten

  • Consultant; MD, PhD
 

Publications 2021

Aarskog NR, Aass HC, Holter JC, Rostrup M, Holten AR (2021)
Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?
Crit Care Explor, 3 (10), e0542
DOI 10.1097/CCE.0000000000000542, PubMed 34604785

Amundsen EK, Binde C, Christensen EE, Klingenberg O, Kvale D, Holten AR (2021)
Prognostic Value of Nucleated RBCs for Patients With Suspected Sepsis in the Emergency Department: A Single-Center Prospective Cohort Study
Crit Care Explor, 3 (7), e0490
DOI 10.1097/CCE.0000000000000490, PubMed 34291222

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Carr E, Bendayan R, Bean D, Stammers M, Wang W, Zhang H, Searle T, Kraljevic Z, Shek A, Phan HTT, Muruet W, Gupta RK, Shinton AJ, Wyatt M, Shi T, Zhang X, Pickles A, Stahl D, Zakeri R, Noursadeghi M, O'Gallagher K, Rogers M, Folarin A, Karwath A, Wickstrøm KE et al. (2021)
Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study
BMC Med, 19 (1), 23
DOI 10.1186/s12916-020-01893-3, PubMed 33472631

Christensen EE, Jørgensen MJ, Nore KG, Dahl TB, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter JC, Holten AR, Halvorsen B, Dyrhol-Riise AM (2021)
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738

Kåsine T, Dyrhol-Riise AM, Barratt-Due A, Kildal AB, Olsen IC, Nezvalova-Henriksen K, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Berg Å, Johannessen A, Heggelund L, Dahl TB, Halvorsen B, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR et al. (2021)
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med
DOI 10.1111/joim.13377, PubMed 34411368

Kolberg ES, Wickstrøm K, Tonby K, Dyrhol-Riise AM, Holten AR, Amundsen EK (2021)
Serum ACE as a prognostic biomarker in COVID-19: a case series
APMIS, 129 (4), 237-238
DOI 10.1111/apm.13108, PubMed 33368687

Watne LO, Tonby K, Holten AR, Olasveengen TM, Romundstad LG, Neerland BE (2021)
Delirium is common in patients hospitalized with COVID-19
Intern Emerg Med, 16 (7), 1997-2000
DOI 10.1007/s11739-021-02715-x, PubMed 33830418

Wickstrøm KE, Vitelli V, Carr E, Holten AR, Bendayan R, Reiner AH, Bean D, Searle T, Shek A, Kraljevic Z, Teo J, Dobson R, Tonby K, Köhn-Luque A, Amundsen EK (2021)
Regional performance variation in external validation of four prediction models for severity of COVID-19 at hospital admission: An observational multi-centre cohort study
PLoS One, 16 (8), e0255748
DOI 10.1371/journal.pone.0255748, PubMed 34432797

Publications 2020

Gundem T, Olasveengen TM, Hovda KE, Gaustad K, Schøndorf C, Rostrup M, Frøyshov S, Undseth Ø, Tonby K, Holten AR, Sunde K (2020)
Ventilatory support for hypoxaemic intensive care patients with COVID-19
Tidsskr Nor Laegeforen, 140 (11)
DOI 10.4045/tidsskr.20.0445, PubMed 32815344

Gundem T, Olasveengen TM, Hovda KE, Gaustad K, Schøndorf C, Rostrup M, Frøyshov S, Undseth Ø, Tonby K, Holten AR, Sunde K (2020)
T.M. Gundem and colleagues respond
Tidsskr Nor Laegeforen, 140 (12)
DOI 10.4045/tidsskr.20.0650, PubMed 32900164

Holten AR, Nore KG, Tveiten CEVWK, Olasveengen TM, Tonby K (2020)
Predicting severe COVID-19 in the Emergency Department
Resusc Plus, 4, 100042
DOI 10.1016/j.resplu.2020.100042, PubMed 33403367

Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538

Jøntvedt Jørgensen M, Holter JC, Christensen EE, Schjalm C, Tonby K, Pischke SE, Jenum S, Skeie LG, Nur S, Lind A, Opsand H, Enersen TB, Grøndahl R, Hermann A, Dudman S, Muller F, Ueland T, Mollnes TE, Aukrust P, Heggelund L, Holten AR, Dyrhol-Riise AM (2020)
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7, PubMed 33303843

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol, 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Ueland T, Holter JC, Holten AR, Müller KE, Lind A, Bekken GK, Dudman S, Aukrust P, Dyrhol-Riise AM, Heggelund L (2020)
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675

Publications 2019

Trydal E, Martinsen AB, Beisland F, Jacobsen D, Holten AR (2019)
Structured evaluation on arrival of patients with sepsis and initiation of antibiotics
Tidsskr Nor Laegeforen, 139 (9)
DOI 10.4045/tidsskr.18.0216, PubMed 31140244

Trydal E, Martinsen AB, Beisland F, Jacobsen D, Holten AR (2019)
Structured reception of sepsis patients and initiation of antibiotics
Tidsskr. Nor. Laegeforen., 139 (9), 811-816

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