Publications 2020

Hoel H, Heggelund L, Reikvam DH, Stiksrud B, Ueland T, Michelsen AE, Otterdal K, Muller KE, Lind A, Muller F, Dudman S, Aukrust P, Dyrhol-Riise AM, Holter JC, Trøseid M (2020)
Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
J Intern Med
DOI 10.1111/joim.13178, PubMed 32976665

Hoel IM, Sviland L, Syre H, Dyrhol-Riise AM, Skarstein I, Jebsen P, Jørstad MD, Wiker H, Mustafa T (2020)
Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting
BMC Infect Dis, 20 (1), 130
DOI 10.1186/s12879-020-4852-z, PubMed 32050915

Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538

Mustafa T, Wergeland I, Baba K, Pathak S, Hoosen AA, Dyrhol-Riise AM (2020)
Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients
BMC Infect Dis, 20 (1), 459
DOI 10.1186/s12879-020-05165-6, PubMed 32611401

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J Allergy Clin Immunol (in press)
DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109

Ueland T, Holter JC, Holten AR, Müller KE, Lind A, Bekken GK, Dudman S, Aukrust P, Dyrhol-Riise AM, Heggelund L (2020)
Distinct and early increase in circulating MMP-9 in COVID-19 patients with respiratory failure
J Infect, 81 (3), e41-e43
DOI 10.1016/j.jinf.2020.06.061, PubMed 32603675

Publications 2019

Hoel IM, Jørstad MD, Marijani M, Ruhwald M, Mustafa T, Dyrhol-Riise AM (2019)
IP-10 dried blood spots assay monitoring treatment efficacy in extrapulmonary tuberculosis in a low-resource setting
Sci Rep, 9 (1), 3871
DOI 10.1038/s41598-019-40458-0, PubMed 30846768

Jørstad MD, Dyrhol-Riise AM, Aßmus J, Marijani M, Sviland L, Mustafa T (2019)
Evaluation of treatment response in extrapulmonary tuberculosis in a low-resource setting
BMC Infect Dis, 19 (1), 426
DOI 10.1186/s12879-019-4034-z, PubMed 31096926

Mortensen R, Clemmensen HS, Woodworth JS, Therkelsen ML, Mustafa T, Tonby K, Jenum S, Agger EM, Dyrhol-Riise AM, Andersen P (2019)
Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice
Commun Biol, 2, 288
DOI 10.1038/s42003-019-0530-3, PubMed 31396568

Stiksrud B, Aass HCD, Lorvik KB, Ueland T, Trøseid M, Dyrhol-Riise AM (2019)
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356

Storm-Larsen C, Stiksrud B, Eriksen C, Nowak P, Holm K, Thalme A, Dyrhol-Riise AM, Brix S, Hov JR, Trøseid M (2019)
Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals
AIDS, 33 (4), 645-653
DOI 10.1097/QAD.0000000000002087, PubMed 30531315

Tonby K, Mortensen R, Ruhwald M, Dyrhol-Riise AM, Jenum S (2019)
KLRG1-Expressing CD4 T Cells Are Reduced in Tuberculosis Patients Compared to Healthy Mycobacterium tuberculosis-Infected Subjects, but Increase With Treatment
J Infect Dis, 220 (1), 174-176
DOI 10.1093/infdis/jiz056, PubMed 30888024

Publications 2018

Habtamu M, Abebe M, Aseffa A, Dyrhol-Riise AM, Spurkland A, Abrahamsen G (2018)
In vitro analysis of antigen induced T cell-monocyte conjugates by imaging flow cytometry
J Immunol Methods, 460, 93-100
DOI 10.1016/j.jim.2018.06.014, PubMed 29981305

Jørstad MD, Marijani M, Dyrhol-Riise AM, Sviland L, Mustafa T (2018)
MPT64 antigen detection test improves routine diagnosis of extrapulmonary tuberculosis in a low-resource setting: A study from the tertiary care hospital in Zanzibar
PLoS One, 13 (5), e0196723
DOI 10.1371/journal.pone.0196723, PubMed 29742144

Orlien SMS, Ismael NY, Ahmed TA, Berhe N, Lauritzen T, Roald B, Goldin RD, Stene-Johansen K, Dyrhol-Riise AM, Gundersen SG, Morgan MY, Johannessen A (2018)
Unexplained chronic liver disease in Ethiopia: a cross-sectional study
BMC Gastroenterol, 18 (1), 27
DOI 10.1186/s12876-018-0755-5, PubMed 29439653

Quist-Paulsen E, Aukrust P, Kran AB, Dunlop O, Ormaasen V, Stiksrud B, Midttun Ø, Ueland T, Ueland PM, Mollnes TE, Dyrhol-Riise AM (2018)
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234

Sane Schepisi M, Navarra A, Altet Gomez MN, Dudnyk A, Dyrhol-Riise AM, Esteban J, Giorgetti PF, Gualano G, Guglielmetti L, Heyckendorf J, Kaluzhenina A, Lange B, Lange C, Manika K, Miah J, Nanovic Z, Pontali E, Prego MR, Solovic I, Tiberi S, Palmieri F, Girardi E (2018)
Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study
Open Forum Infect Dis, 6 (1), ofy337
DOI 10.1093/ofid/ofy337, PubMed 30697572

Schein YL, Madebo T, Andersen HE, Arnesen TM, Dyrhol-Riise AM, Tveiten H, White RA, Winje BA (2018)
Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study
BMC Infect Dis, 18 (1), 587
DOI 10.1186/s12879-018-3468-z, PubMed 30453946

Publications 2017

Brekke K, Sommerfelt M, Ökvist M, Dyrhol-Riise AM, Kvale D (2017)
The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study
BMC Infect Dis, 17 (1), 228
DOI 10.1186/s12879-017-2316-x, PubMed 28340570

Feruglio SL, Kvale D, Dyrhol-Riise AM (2017)
T Cell Responses and Regulation and the Impact of In Vitro IL-10 and TGF-β Modulation During Treatment of Active Tuberculosis
Scand J Immunol, 85 (2), 138-146
DOI 10.1111/sji.12511, PubMed 27862137

Prebensen C, Trøseid M, Ueland T, Dahm A, Sandset PM, Aaberge I, Waalen K, Dyrhol-Riise AM, Taskén K, Kvale D (2017)
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
PLoS One, 12 (5), e0176527
DOI 10.1371/journal.pone.0176527, PubMed 28464042

Publications 2016

Jensenius M, Winje BA, Blomberg B, Mengshoel AT, Lippe Bv, Hannula R, Bruun JN, Knudsen PK, Rønning JO, Heldal E, Dyrhol-Riise AM (2016)
Multidrug-resistant tuberculosis in Norway: a nationwide study, 1995-2014
Int J Tuberc Lung Dis, 20 (6), 786-92
DOI 10.5588/ijtld.15.0895, PubMed 27155182

Prebensen C, Lind A, Dyrhol-Riise AM, Kvale D (2016)
Regulation of Gag- and Env-Specific CD8+ T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy
PLoS One, 11 (4), e0153849
DOI 10.1371/journal.pone.0153849, PubMed 27128502

Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
J Acquir Immune Defic Syndr, 73 (2), 138-48
DOI 10.1097/QAI.0000000000001080, PubMed 27632144

Tonby K, Wergeland I, Lieske NV, Kvale D, Tasken K, Dyrhol-Riise AM (2016)
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
BMC Infect Dis, 16 (1), 599
DOI 10.1186/s12879-016-1938-8, PubMed 27776487

Wergeland I, Assmus J, Dyrhol-Riise AM (2016)
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
PLoS One, 11 (9), e0163848
DOI 10.1371/journal.pone.0163848, PubMed 27685462

Publications 2015

Feruglio SL, Tonby K, Kvale D, Dyrhol-Riise AM (2015)
Early dynamics of T helper cell cytokines and T regulatory cells in response to treatment of active Mycobacterium tuberculosis infection
Clin Exp Immunol, 179 (3), 454-65
DOI 10.1111/cei.12468, PubMed 25313008

Lieske NV, Tonby K, Kvale D, Dyrhol-Riise AM, Tasken K (2015)
Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors
PLoS One, 10 (11), e0141903
DOI 10.1371/journal.pone.0141903, PubMed 26544592

Prebensen C, Ueland T, Michelsen AE, Lind A, Pettersen FO, Mollnes TE, Aukrust P, Dyrhol-Riise AM, Kvale D (2015)
High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
J Acquir Immune Defic Syndr, 69 (4), 395-402
DOI 10.1097/QAI.0000000000000617, PubMed 26115437

Riise AMD (2015)
Our Voices HIV: 30 years in Norway
Tidsskr. Nor. Laegeforen., 135 (19), 1769

Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571

Tonby K, Ruhwald M, Kvale D, Dyrhol-Riise AM (2015)
IP-10 measured by Dry Plasma Spots as biomarker for therapy responses in Mycobacterium Tuberculosis infection
Sci Rep, 5, 9223
DOI 10.1038/srep09223, PubMed 25783975

Wergeland I, Pullar N, Assmus J, Ueland T, Tonby K, Feruglio S, Kvale D, Damås JK, Aukrust P, Mollnes TE, Dyrhol-Riise AM (2015)
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
J Infect, 70 (4), 381-91
DOI 10.1016/j.jinf.2014.12.019, PubMed 25597826

Publications 2014

Eldholm V, Norheim G, von der Lippe B, Kinander W, Dahle UR, Caugant DA, Mannsåker T, Mengshoel AT, Dyrhol-Riise AM, Balloux F (2014)
Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient
Genome Biol, 15 (11), 490
DOI 10.1186/s13059-014-0490-3, PubMed 25418686

Pettersen PS, Brox IK, Naman E, Bruun JN, Dyrhol-Riise AM, Trøseid M, Johannessen A (2014)
Antiretroviral treatment failure predicts mortality in rural Tanzania
Int J STD AIDS, 26 (9), 633-9
DOI 10.1177/0956462414548460, PubMed 25122578

Pullar ND, Steinum H, Bruun JN, Dyrhol-Riise AM (2014)
HIV patients with latent tuberculosis living in a low-endemic country do not develop active disease during a 2 year follow-up; a Norwegian prospective multicenter study
BMC Infect Dis, 14, 667
DOI 10.1186/s12879-014-0667-0, PubMed 25515915

Pullar ND, Steinum H, Tonby K, Heggelund L, Leiva RA, Ofstad R, Bruun JN, Dyrhol-Riise AM (2014)
Low prevalence of positive interferon-gamma tests in HIV-positive long-term immigrants in Norway
Int J Tuberc Lung Dis, 18 (2), 180-7
DOI 10.5588/ijtld.13.0276, PubMed 24429310

Publications 2013

Feruglio SL, Trøseid M, Damås JK, Kvale D, Dyrhol-Riise AM (2013)
Soluble markers of the Toll-like receptor 4 pathway differentiate between active and latent tuberculosis and are associated with treatment responses
PLoS One, 8 (7), e69896
DOI 10.1371/journal.pone.0069896, PubMed 23875007

Gran G, Aßmus J, Dyrhol-Riise AM (2013)
Screening for latent tuberculosis in Norwegian health care workers: high frequency of discordant tuberculin skin test positive and interferon-gamma release assay negative results
BMC Public Health, 13, 353
DOI 10.1186/1471-2458-13-353, PubMed 23590619

Lind A, Brekke K, Sommerfelt M, Holmberg JO, Aass HC, Baksaas I, Sørensen B, Dyrhol-Riise AM, Kvale D (2013)
Boosters of a therapeutic HIV-1 vaccine induce divergent T cell responses related to regulatory mechanisms
Vaccine, 31 (41), 4611-8
DOI 10.1016/j.vaccine.2013.07.037, PubMed 23906886

Publications 2011

Hesstvedt L, Wilhelmsen M, Mengshoel AT, Dyrhol-Riise AM (2011)
Two Norwegian patients with melioidosis presenting with bacteraemia and splenic and prostatic abscesses
J Travel Med, 18 (6), 418-21
DOI 10.1111/j.1708-8305.2011.00550.x, PubMed 22017720

Wergeland I, Assmus J, Dyrhol-Riise AM (2011)
T regulatory cells and immune activation in Mycobacterium tuberculosis infection and the effect of preventive therapy
Scand J Immunol, 73 (3), 234-42
DOI 10.1111/j.1365-3083.2010.02496.x, PubMed 21204895

Publications 2010

Dyrhol-Riise AM, Gran G, Wentzel-Larsen T, Blomberg B, Haanshuus CG, Mørkve O (2010)
Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country
BMC Infect Dis, 10, 57
DOI 10.1186/1471-2334-10-57, PubMed 20210999

Publications 2009

Storla DG, Kristiansen I, Oftung F, Korsvold GE, Gaupset M, Gran G, Øverby AK, Dyrhol-Riise AM, Bjune GA (2009)
Use of interferon gamma-based assay to diagnose tuberculosis infection in health care workers after short term exposure
BMC Infect Dis, 9, 60
DOI 10.1186/1471-2334-9-60, PubMed 19432995

Publications 2008

Baba K, Dyrhol-Riise AM, Sviland L, Langeland N, Hoosen AA, Wiker HG, Mustafa T (2008)
Rapid and specific diagnosis of tuberculous pleuritis with immunohistochemistry by detecting Mycobacterium tuberculosis complex specific antigen MPT64 in patients from a HIV endemic area
Appl Immunohistochem Mol Morphol, 16 (6), 554-61
DOI 10.1097/PAI.0b013e31816c3f79, PubMed 18698260

Baba K, Hoosen AA, Langeland N, Dyrhol-Riise AM (2008)
Adenosine deaminase activity is a sensitive marker for the diagnosis of tuberculous pleuritis in patients with very low CD4 counts
PLoS One, 3 (7), e2788
DOI 10.1371/journal.pone.0002788, PubMed 18665218

Baba K, Pathak S, Sviland L, Langeland N, Hoosen AA, Asjo B, Dyrhol-Riise AM, Mustafa T (2008)
Real-time quantitative PCR in the diagnosis of tuberculosis in formalin-fixed paraffin-embedded pleural tissue in patients from a high HIV endemic area
Diagn Mol Pathol, 17 (2), 112-7
DOI 10.1097/PDM.0b013e31814ceac3, PubMed 18382372

Baba K, Sørnes S, Hoosen AA, Lekabe JM, Mpe MJ, Langeland N, Dyrhol-Riise AM (2008)
Evaluation of immune responses in HIV infected patients with pleural tuberculosis by the QuantiFERON TB-Gold interferon-gamma assay
BMC Infect Dis, 8, 35
DOI 10.1186/1471-2334-8-35, PubMed 18366633

Winje BA, Oftung F, Korsvold GE, Mannsåker T, Ly IN, Harstad I, Dyrhol-Riise AM, Heldal E (2008)
School based screening for tuberculosis infection in Norway: comparison of positive tuberculin skin test with interferon-gamma release assay
BMC Infect Dis, 8, 140
DOI 10.1186/1471-2334-8-140, PubMed 18928541

Publications 2006

Voltersvik P, Bostad L, Dyrhol-Riise AM, Eide GE, Røsok BI, Olofsson J, Asjö B (2006)
Cystatin A and HIV-1 p24 antigen expression in tonsillar lymphoid follicles during HIV-1 infection and during highly active antiretroviral therapy
J Acquir Immune Defic Syndr, 41 (3), 277-84
DOI 10.1097/01.qai.0000199234.77081.a2, PubMed 16540928

Wiker HG, Mustafa T, Målen H, Riise AM (2006)
Vaccine approaches to prevent tuberculosis
Scand J Immunol, 64 (3), 243-50
DOI 10.1111/j.1365-3083.2006.01815.x, PubMed 16918693

Publications 2003

Voltersvik P, Albrektsen G, Ulvestad E, Dyrhol-Riise AM, Sørensen B, Asjö B (2003)
Changes in immunoglobulin isotypes and immunoglobulin G (IgG) subclasses during highly active antiretroviral therapy: anti-p24 IgG1 closely parallels the biphasic decline in plasma viremia
J Acquir Immune Defic Syndr, 34 (4), 358-67
DOI 10.1097/00126334-200312010-00002, PubMed 14615653

Publications 2001

Dyrhol-Riise AM, Ohlsson M, Skarstein K, Nygaard SJ, Olofsson J, Jonsson R, Asjö B (2001)
T cell proliferation and apoptosis in HIV-1-infected lymphoid tissue: impact of highly active antiretroviral therapy
Clin Immunol, 101 (2), 180-91
DOI 10.1006/clim.2001.5102, PubMed 11683577

Dyrhol-Riise AM, Stent G, Røsok BI, Voltersvik P, Olofsson J, Asjö B (2001)
The Fas/FasL system and T cell apoptosis in HIV-1-infected lymphoid tissue during highly active antiretroviral therapy
Clin Immunol, 101 (2), 169-79
DOI 10.1006/clim.2001.5101, PubMed 11683576

Dyrhol-Riise AM, Voltersvik P, Berg OG, Olofsson J, Kleivbo S, Asjö B (2001)
Residual human immunodeficiency virus type 1 infection in lymphoid tissue during highly active antiretroviral therapy: quantitation and virus characterization
AIDS Res Hum Retroviruses, 17 (7), 577-86
DOI 10.1089/088922201300119671, PubMed 11375053

Publications 2000

Dyrhol-Riise AM (2000)
Human immunodeficiency virus type I (HIV-1) infection andhighly active antiretroviral therapy: virus dynamics and immune reconstitution in blood and tonsillar tissue
Centre for Research in Virology, Department of Microbiology and Immunology, The Gade Institute, University of Bergen, Bergen, 1 b. (flere pag.)
BIBSYS 001595962, ISBN 82-7788-086-3

Dyrhol-Riise AM, Brantsaeter AB, Dunlop O, Baklien K, Skar AG, Asjö B, Bruun JN, Røsok BI (2000)
Early changes in peripheral blood T cell subsets induced by antiretroviral treatment of human immunodeficiency virus-1 positive individuals
Scand J Immunol, 51 (2), 195-201
DOI 10.1046/j.1365-3083.2000.00659.x, PubMed 10652164

Dyrhol-Riise AM, Voltersvik P, Røsok BI, Olofsson J, Asjö B (2000)
Normalization of CD4+ cell numbers and reduced levels of memory CD8+ cells in blood and tonsillar tissue after highly active antiretroviral therapy in early HIV type-1 infection
AIDS Res Hum Retroviruses, 16 (3), 191-201
DOI 10.1089/088922200309287, PubMed 10710207

Voltersvik P, Dyrhol-Riise AM, Bostad L, Røsok BI, Olofsson J, Asjö B (2000)
Changes in tonsillar tissue in early HIV-1 infection and during 3 years of antiretroviral therapy
APMIS, 108 (7-8), 539-50
DOI 10.1034/j.1600-0463.2000.d01-94.x, PubMed 11167551

Publications 1999

Dyrhol-Riise AM, Voltersvik P, Olofsson J, Asjö B (1999)
Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection
AIDS, 13 (17), 2365-76
DOI 10.1097/00002030-199912030-00008, PubMed 10597778