Arne K. Andreassen

  • Consultant Cardiologist; MD, PhD
  • +47 230 72014
 

Publications 2021

Didriksen H, Molberg O, Fretheim H, Gude E, Jordan S, Brunborg C, Palchevskiy V, Garen T, Midtvedt O, Andreassen AK, Distler O, Belperio J, Hoffmann-Vold AM (2021)
Association of Lymphangiogenic Factors With Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol., 73 (7), 1277-1287
DOI 10.1002/art.41665

Englund KVB, Ostby CM, Rolid K, Gude E, Andreassen AK, Gullestad L, Broch K (2021)
Intravenous iron supplement for iron deficiency in cardiac transplant recipients (IronIC): A randomized clinical trial
J. Heart Lung Transplant., 40 (5), 359-367
DOI 10.1016/j.healun.2021.01.1390

Englund KVB, Ostby CM, Tjonnas G, Gude E, Andreassen AK, Gullestad L, Broch K (2021)
Prevalence of iron deficiency in heart transplant recipients
Clin. Transplant., 35 (8), e14346
DOI 10.1111/ctr.14346

Ueland T, Abraityte A, Norum H, Varathalingam S, Gullestad L, Aukrust P, Andreassen AK (2021)
Circulating regulators of the wingless pathway in precapillary pulmonary hypertension
Respirology, 26 (6), 574-581
DOI 10.1111/resp.14048

Publications 2020

Bergh N, Gude E, Bartfay SE, Andreassen AK, Arora S, Dahlberg P, Dellgren G, Gullestad L, Gustafsson F, Karasson K, Radegran G, Bollano E, Andersson B (2020)
Invasive haemodynamics in de novo everolimus vs. calcineurin inhibitor heart transplant recipients
ESC Heart Fail., 7 (2), 567-576
DOI 10.1002/ehf2.12608

Broch K, Gude E, Karason K, Dellgren G, Radegran G, Gjesdal G, Gustafsson F, Eiskjaer H, Lommi J, Pentikainen M, Lemstrom KB, Andreassen AK, Gullestad L (2020)
Cholesterol lowering with EVOLocumab to prevent cardiac allograft Vasculopathy in De-novo heart transplant recipients: Design of the randomized controlled EVOLVD trial
Clin. Transplant., 34 (9), e13984
DOI 10.1111/ctr.13984

Gustafsson F, Andreassen AK, Andersson B, Eiskjaer H, Radegran G, Gude E, Jansson K, Solbu D, Karason K, Arora S, Dellgren G, Gullestad L, SCHEDULE Scandinavian Heart Transp (2020)
Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Long-term Follow-up From the Randomized SCHEDULE Study
Transplantation, 104 (1), 154-164
DOI 10.1097/TP.0000000000002702

Lekva T, Gullestad L, Broch K, Aukrust P, Andreassen AK, Ueland T (2020)
Distinct patterns of soluble leukocyte activation markers are associated with etiology and outcomes in precapillary pulmonary hypertension
Sci Rep, 10 (1), 18540
DOI 10.1038/s41598-020-75654-w

Nelson LM, Andreassen AK, Arora S, Andersson B, Gude E, Eiskjaer H, Radegran G, Dellgren G, Gullestad L, Gustafsson F (2020)
Mild acute cellular rejection and development of cardiac allograft vasculopathy assessed by intravascular ultrasound and coronary angiography in heart transplant recipients-a SCHEDULE trial substudy
Transpl. Int., 33 (5), 517-528
DOI 10.1111/tri.13577

Rolid K, Andreassen AK, Yardley M, Gude E, Bjorkelund E, Authen AR, Grov I, Broch K, Gullestad L, Nytroen K (2020)
Long-term effects of high-intensity training vs moderate intensity training in heart transplant recipients: A 3-year follow-up study of the randomized-controlled HITTS study
Am. J. Transplant., 20 (12), 3538-3549
DOI 10.1111/ajt.16087

Rolid K, Andreassen AK, Yardley M, Gude E, Bjorkelund E, Authen AR, Grov I, Pettersen KI, Dall CH, Karason K, Broch K, Gullestad L, Nytroen K (2020)
High-intensity interval training and health-related quality of life in de novo heart transplant recipients - results from a randomized controlled trial
Health Qual. Life Outcomes, 18 (1), 283
DOI 10.1186/s12955-020-01536-4

Publications 2019

Andreassen AK, Broch K, Eiskjaer H, Karason K, Gude E, Molbak D, Stueflotten W, Gullestad L, SCHEDULE SCandinavian HEart (2019)
Blood Pressure in De Novo Heart Transplant Recipients Treated With Everolimus Compared With a Cyclosporine-based Regimen: Results From the Randomized SCHEDULE Trial
Transplantation, 103 (4), 781-788
DOI 10.1097/TP.0000000000002445

Burker BS, Gullestad L, Gude E, Havik OE, Authen AR, Grov I, Andreassen AK, Fiane AE, Haraldsen IR, Amanda M, Andersson S, Malt UF (2019)
The Predictive Value of Depression in the Years After Heart Transplantation for Mortality During Long-Term Follow-Up
Psychosom. Med., 81 (6), 513-520
DOI 10.1097/PSY.0000000000000702

Norum HM, Michelsen AE, Lekva T, Arora S, Otterdal K, Olsen MB, Kong XY, Gude E, Andreassen AK, Solbu D, Karason K, Dellgren G, Gullestad L, Aukrust P, Ueland T (2019)
Circulating delta-like Notch ligand 1 is correlated with cardiac allograft vasculopathy and suppressed in heart transplant recipients on everolimus-based immunosuppression
Am. J. Transplant., 19 (4), 1050-1060
DOI 10.1111/ajt.15141

Nytroen K, Rolid K, Andreassen AK, Yardley M, Gude E, Dahle DO, Bjorkelund E, Authen AR, Grov I, Wigh JP, Dall CH, Gustafsson F, Karason K, Gullestad L (2019)
Effect of High-Intensity Interval Training in De Novo Heart Transplant Recipients in Scandinavia One-Year Follow-Up of the HITTS Randomized, Controlled Study
Circulation, 139 (19), 2198-2211
DOI 10.1161/CIRCULATIONAHA.118.036747

Troseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
J. Heart Lung Transplant., 38 (10), 1097-1103
DOI 10.1016/j.healun.2019.06.003

Publications 2018

Arora S, Andreassen AK, Karason K, Gustafsson F, Eiskjaer H, Botker HE, Radegran G, Gude E, Ioanes D, Solbu D, Dellgren G, Ueland T, Aukrust P, Gullestad L, SCHEDULE Scandinavian Heart Traspl (2018)
Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Heart Transplant Recipients Three-Year Results of a Scandinavian Randomized Trial
Circ.-Heart Fail., 11 (9), e004050
DOI 10.1161/CIRCHEARTFAILURE.117.004050

Gilljam T, Haugaa KH, Jensen HK, Svensson A, Bundgaard H, Hansen J, Dellgren G, Gustafsson F, Eiskjaer H, Andreassen AK, Sjogren J, Edvardsen T, Holst AG, Svendsen JH, Platonov PG (2018)
Heart transplantation in arrhythmogenic right ventricular cardiomyopathy - Experience from the Nordic ARVC Registry
Int. J. Cardiol., 250, 201-206
DOI 10.1016/j.ijcard.2017.10.076

Hoffmann-Vold AM, Fretheim H, Midtvedt O, Kilian K, Angelshaug M, Chaudhary A, Gunnarsson R, Brunborg C, Garen T, Andreassen AK, Gude E, Molberg O (2018)
Frequencies of borderline pulmonary hypertension before and after the DETECT algorithm: results from a prospective systemic sclerosis cohort
RHEUMATOLOGY, 57 (3), 480-487
DOI 10.1093/rheumatology/kex435

Hoffmann-Vold AM, Hesselstrand R, Fretheim H, Ueland T, Andreassen AK, Brunborg C, Palchevskiy V, Midtvedt O, Garen T, Aukrust P, Belperio JA, Molberg O (2018)
CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol., 70 (10), 1644-1653
DOI 10.1002/art.40534

Soleng A, Edgar KS, Paulsen KM, Pedersen BN, Okbaldet YB, Skjetne IEB, Gurung D, Vikse R, Andreassen AK (2018)
Distribution of Ixodes ricinus ticks and prevalence of tick-borne encephalitis virus among questing ticks in the Arctic Circle region of northern Norway
Ticks Tick-Borne Dis., 9 (1), 97-103
DOI 10.1016/j.ttbdis.2017.10.002

Publications 2017

Authen AR, Grov I, Karason K, Gustafsson F, Eiskjaer H, Radegran G, Gude E, Jansson K, Dellgren G, Solbu D, Arora S, Andreassen AK, Gullestad L, SCHEDULE Investigators (2017)
Effect of everolimus vs calcineurin inhibitors on quality of life in heart transplant recipients during a 3-year follow-up: Results of a randomized controlled trial (SCHEDULE)
Clin. Transplant., 31 (9), e13038
DOI 10.1111/ctr.13038

Burker BS, Gude E, Gullestad L, Grov I, Authen AR, Andreassen AK, Havik OE, Dew MA, Fiane AE, Haraldsen IR, Malt UF, Andersson S (2017)
Cognitive function among long-term survivors of heart transplantation
Clin. Transplant., 31 (12), e13143
DOI 10.1111/ctr.13143

Burker BS, Gullestad L, Gude E, Authen AR, Grov I, Hol PK, Andreassen AK, Arora S, Dew MA, Fiane AE, Haraldsen IR, Malt UF, Andersson S (2017)
Cognitive function after heart transplantation: Comparing everolimus-based and calcineurin inhibitor-based regimens
Clin. Transplant., 31 (4), e12927
DOI 10.1111/ctr.12927

Gude E, Gullestad L, Andreassen AK (2017)
Everolimus immunosuppression for renal protection, reduction of allograft vasculopathy and prevention of allograft rejection in de-novo heart transplant recipients: could we have it all?
Curr. Opin. Organ Transpl., 22 (3), 198-206
DOI 10.1097/MOT.0000000000000409

Hoffmann-Vold AM, Midtvedt O, Tennoe AH, Garen T, Lund MB, Aalokken TM, Andreassen AK, Elhage F, Brunborg C, Taraldsrud E, Molberg O (2017)
Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort
J. Rheumatol., 44 (4), 459-465
DOI 10.3899/jrheum.160867

Nelson LM, Andreassen AK, Andersson B, Gude E, Eiskjaer H, Radegran G, Dellgren G, Gullestad L, Gustafsson F (2017)
Effect of Calcineurin Inhibitor-Free, Everolimus-Based Immunosuppressive Regimen on Albuminuria and Glomerular Filtration Rate After Heart Transplantation
Transplantation, 101 (11), 2793-2800
DOI 10.1097/TP.0000000000001706

Norum HM, Broch K, Michelsen AE, Lunde IG, Lekva T, Abraityte A, Dahl CP, Fiane AE, Andreassen AK, Christensen G, Aakhus S, Aukrust P, Gullestad L, Ueland T (2017)
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J. Cardiovasc. Transl. Res., 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y

Publications 2016

Andreassen AK, Andersson B, Gustafsson F, Eiskjaer H, Radegran G, Gude E, Jansson K, Solbu D, Karason K, Arora S, Dellgren G, Gullestad L, SCHEDULE Investigators (2016)
Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Three-Year Results From the Randomized SCHEDULE Study
Am. J. Transplant., 16 (4), 1238-1247
DOI 10.1111/ajt.13588

Broch K, Murbraech K, Ragnarsson A, Gude E, Andersen R, Fiane AE, Andreassen J, Aakhus S, Andreassen AK (2016)
Echocardiographic evidence of right ventricular functional improvement after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension
J. Heart Lung Transplant., 35 (1), 80-86
DOI 10.1016/j.healun.2015.08.007

Solberg OG, Stavem K, Ragnarsson A, Ioanes D, Arora S, Endresen K, Benth JS, Gullestad L, Gude E, Andreassen AK, Aaberge L (2016)
Index of microvascular resistance after early conversion from calcineurin inhibitor to everolimus in heart transplantation: A sub-study to a 1-year randomized trial
J. Heart Lung Transplant., 35 (8), 1010-1017
DOI 10.1016/j.healun.2016.03.002

Publications 2015

Arora S, Andreassen AK, Andersson B, Gustafsson F, Eiskjaer H, Botker HE, Radegran G, Gude E, Ioanes D, Solbu D, Sigurdardottir V, Dellgren G, Erikstad I, Solberg OG, Ueland T, Aukrust P, Gullestad L, SCHEDULE SCandinavian HEart Trans (2015)
The Effect of Everolimus Initiation and Calcineurin Inhibitor Elimination on Cardiac Allograft Vasculopathy in De Novo Recipients: One-Year Results of a Scandinavian Randomized Trial
Am. J. Transplant., 15 (7), 1967-1975
DOI 10.1111/ajt.13214

Broch K, Andreassen AK, Hopp E, Leren TP, Scott H, Muller F, Aakhus S, Gullestad L (2015)
Results of comprehensive diagnostic work-up in 'idiopathic' dilated cardiomyopathy
Open Heart, 2 (1), UNSP e000271
DOI 10.1136/openhrt-2015-000271

Broch K, Andreassen AK, Ueland T, Michelsen AE, Stueflotten W, Aukrus P, Aakhus S, Gullestad L (2015)
Soluble ST2 reflects hemodynamic stress in non-ischemic heart failure
Int. J. Cardiol., 179, 378-384
DOI 10.1016/j.ijcard.2014.11.003

Broch K, Murbraech K, Andreassen AK, Hopp E, Aakhus S, Gullestad L (2015)
Contemporary Outcome in Patients With Idiopathic Dilated Cardiomyopathy
Am. J. Cardiol., 116 (6), 952-959
DOI 10.1016/j.amjcard.2015.06.022

Hasselberg NE, Haugaa KH, Sarvari SI, Gullestad L, Andreassen AK, Smiseth OA, Edvardsen T (2015)
Left ventricular global longitudinal strain is associated with exercise capacity in failing hearts with preserved and reduced ejection fraction
Eur. Heart J.-Cardiovasc. Imaging, 16 (2), 217-224
DOI 10.1093/ehjci/jeu277

Publications 2014

Andreassen AK, Andersson B, Gustafsson F, Eiskjaer H, Rdegran G, Gude E, Jansson K, Solbu D, Sigurdardottir V, Arora S, Dellgren G, Gullestad L, SCHEDULE Scandinavian Heart (2014)
Everolimus Initiation and Early Calcineurin Inhibitor Withdrawal in Heart Transplant Recipients: A Randomized Trial
Am. J. Transplant., 14 (8), 1828-1838
DOI 10.1111/ajt.12809

Publications 2013

Andreassen AK, Ragnarsson A, Gude E, Geiran O, Andersen R (2013)
Balloon pulmonary angioplasty in patients with inoperable chronic thromboembolic pulmonary hypertension
Heart, 99 (19), 1415-1420
DOI 10.1136/heartjnl-2012-303549

Gunnarsson R, Andreassen AK, Molberg O, Lexberg AS, Time K, Dhainaut ASS, Bertelsen LT, Palm O, Irgens K, Becker-Merok A, Nordeide JL, Johnsen V, Pedersen S, Proven A, Garabet LSN, Garen T, Aalokken TM, Gilboe IM, Gran JT (2013)
Prevalence of pulmonary hypertension in an unselected, mixed connective tissue disease cohort: results of a nationwide, Norwegian cross-sectional multicentre study and review of current literature
RHEUMATOLOGY, 52 (7), 1208-1213
DOI 10.1093/rheumatology/kes430

Robertsen I, Falck P, Andreassen AK, Naess NK, Lunder N, Christensen H, Gullestad L, Asberg A (2013)
Endomyocardial, intralymphocyte, and whole blood concentrations of ciclosporin A in heart transplant recipients
Transplant. Res., 2, 5
DOI 10.1186/2047-1440-2-5

Publications 2012

Sarvari SI, Gjesdal O, Gude E, Arora S, Andreassen AK, Gullestad L, Geiran O, Edvardsen T (2012)
Early Postoperative Left Ventricular Function by Echocardiographic Strain is a Predictor of 1-Year Mortality in Heart Transplant Recipients
J. Am. Soc. Echocardiogr., 25 (9), 1007-1014
DOI 10.1016/j.echo.2012.05.010

Sikkeland LIB, Dahl CP, Ueland T, Andreassen AK, Gude E, Edvardsen T, Holm T, Yndestad A, Gullestad L, Kongerud J, Aukrust P, Oie E (2012)
Increased Levels of Inflammatory Cytokines and Endothelin-1 in Alveolar Macrophages from Patients with Chronic Heart Failure
PLoS One, 7 (5), e36815
DOI 10.1371/journal.pone.0036815

Publications 2011

Larsen KO, Yndestad A, Sjaastad I, Loberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjonsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am. J. Physiol.-Lung Cell. Mol. Physiol., 301 (1), L50-L59
DOI 10.1152/ajplung.00048.2010

Publications 2010

Arora S, Gunther A, Wennerblom B, Ueland T, Andreassen AK, Gude E, Endresen K, Geiran O, Wilhelmsen N, Andersen R, Aukrust P, Gullestad L (2010)
Systemic Markers of Inflammation Are Associated with Cardiac Allograft Vasculopathy and an Increased Intimal Inflammatory Component
Am. J. Transplant., 10 (6), 1428-1436
DOI 10.1111/j.1600-6143.2010.03118.x

Gude E, Andreassen AK, Arora S, Gullestad L, Grov I, Hartmann A, Leivestad T, Fiane AE, Geiran OR, Vardal M, Simonsen S (2010)
Acute renal failure early after heart transplantation: risk factors and clinical consequences
Clin. Transplant., 24 (6), E207-E213
DOI 10.1111/j.1399-0012.2010.01225.x

Gude E, Gullestad L, Arora S, Simonsen S, Hoel I, Hartmann A, Holdaas H, Fiane AE, Geiran OR, Andreassen AK (2010)
Benefit of early conversion from CNI-based to everolimus-based immunosuppression in heart transplantation
J. Heart Lung Transplant., 29 (6), 641-647
DOI 10.1016/j.healun.2010.01.005

Gude E, Simonsen S, Geiran OR, Fiane AE, Gullestad L, Arora S, Relbo A, Andreassen AK (2010)
Pulmonary hypertension in heart transplantation: Discrepant prognostic impact of pre-operative compared with 1-year post-operative right heart hemodynamics
J. Heart Lung Transplant., 29 (2), 216-223
DOI 10.1016/j.healun.2009.08.021

Oie E, Ahmed MS, Ueland T, Sikkeland LIB, Dahl CP, Hagelin EMV, von Lueder T, Edvardsen T, Andreassen AK, Gullestad L, Aukrust P, Yndestad A, Vinge LE, Attramadal H (2010)
Adrenomedullin is increased in alveolar macrophages and released from the lungs into the circulation in severe heart failure
Basic Res. Cardiol., 105 (1), 89-98
DOI 10.1007/s00395-009-0070-y

Publications 2009

Arora S, Aukrust P, Ueland T, Broch K, Simonsen S, Gude E, Fiane AE, Geiran O, Wergeland R, Andreassen AK, Gullestad L (2009)
Elevated serum uric acid levels following heart transplantation predict all-cause and cardiac mortality
Eur. J. Heart Fail., 11 (10), 1005-1013
DOI 10.1093/eurjhf/hfp115

Gjesdal O, Gude E, Arora S, Leivestad T, Andreassen AK, Gullestad L, Aaberge L, Brunvand H, Edvardsen T, Geiran OR, Simonsen S (2009)
Intra-aortic balloon counterpulsation as a bridge to heart transplantation does not impair long-term survival
Eur. J. Heart Fail., 11 (7), 709-714
DOI 10.1093/eurjhf/hfp078

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjonsberg OH, Pedersen TM, Anfinsen OG, Damas JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J. Appl. Physiol., 106 (4), 1356-1364
DOI 10.1152/japplphysiol.90719.2008

Publications 2008

Andreassen AK (2008)
Point: Counterpoint: Cardiac denervation does/does not play a major role in exercise limitation after heart transplantation
J. Appl. Physiol., 104 (2), 559-564
DOI 10.1152/japplphysiol.00694.2007

Otterdal K, Andreassen AK, Yndestad A, Oie E, Sandberg WJ, Dahl CP, Pedersen TM, Ueland T, Gullestad L, Brosstad FR, Aukrust P, Damas JK (2008)
Raised LIGHT levels in pulmonary arterial hypertension potential role in thrombus formation
Am. J. Respir. Crit. Care Med., 177 (2), 202-207
DOI 10.1164/rccm.200703-506OC

Publications 2007

Arora S, Jenum PA, Aukrust P, Rollag H, Andreassen AK, Simonsen S, Gude E, Fiane AE, Geiran O, Gullestad L (2007)
Pre-transplant Toxoplasma gondii seropositivity among heart transplant recipients is associated with an increased risk of all-cause and cardiac mortality
J. Am. Coll. Cardiol., 50 (20), 1967-1972
DOI 10.1016/j.jacc.2007.07.068

Havik OE, Sivertsen B, Relbo A, Hellesvik M, Grov I, Geiran O, Andreassen AK, Simonsen S, Gullestad L (2007)
Depressive symptoms and all-cause mortality after heart transplantation
Transplantation, 84 (1), 97-103
DOI 10.1097/01.tp.0000268816.90672.a0

Publications 2006

Andreassen AK, Smiseth OA, Simonsen S (2006)
Hjertetransplantasjon i Norge: festskrift til Svein Simonsen på hans 70-års dag
Hjertemedisinsk avd., Rikshospitalet, [Oslo], 125 s.
BIBSYS 060292989

Andreassen AK, Wergeland R, Simonsen S, Geiran O, Guevara C, Ueland T (2006)
N-terminal pro-B-type natriuretic peptide as an indicator of disease severity in a heterogeneous group of patients with chronic precapillary pulmonary hypertension
Am. J. Cardiol., 98 (4), 525-529
DOI 10.1016/j.amjcard.2006.02.061

Waehre T, Damas JK, Pedersen TM, Gullestad L, Yndestad A, Andreassen AK, Froland SS, Semb A, Hansteen V, Gjertsen E, Ueland T, Brosstad F, Solum NO, Aukrust P (2006)
Clopidogrel increases expression of chemokines in peripheral blood mononuclear cells in patients with coronary artery disease: results of a double-blind placebo-controlled study
J. Thromb. Haemost., 4 (10), 2140-2147
DOI 10.1111/j.1538-7836.2006.02131.x

Publications 1998

Andreassen AK (1998)
Peripheral microcirculation in human heart transplantation: laser Doppler perfusion measurements of skin microvascular reactivity
Medical Department B, Rikshospitalet, Oslo, 1 b. (flere pag.)
BIBSYS 982289332, ISBN 82-994881-0-9