Pavel Hoffmann

  • Consultant; MD, PhD
 

Publications 2024

Andrup S, Andersen GØ, Hoffmann P, Eritsland J, Seljeflot I, Halvorsen S, Vistnes M (2024)
Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality
PLoS One, 19 (5), e0302732
DOI 10.1371/journal.pone.0302732, PubMed 38739599

Publications 2023

Holm NR, Andreasen LN, Neghabat O, Laanmets P, Kumsars I, Bennett J, Olsen NT, Odenstedt J, Hoffmann P, Dens J, Chowdhary S, O'Kane P, Bülow Rasmussen SH, Heigert M, Havndrup O, Van Kuijk JP, Biscaglia S, Mogensen LJH, Henareh L, Burzotta F, H Eek C, Mylotte D, Llinas MS, Koltowski L, Knaapen P et al. (2023)
OCT or Angiography Guidance for PCI in Complex Bifurcation Lesions
N Engl J Med, 389 (16), 1477-1487
DOI 10.1056/NEJMoa2307770, PubMed 37634149

Publications 2022

Nordeng J, Solheim S, Åkra S, Schandiz H, Hoffmann P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I (2022)
Gene expression of fibrinolytic markers in coronary thrombi
Thromb J, 20 (1), 23
DOI 10.1186/s12959-022-00383-1, PubMed 35488283

Udjus C, Sjaastad I, Hjørnholm U, Tunestveit TK, Hoffmann P, Hinojosa A, Espe EKS, Christensen G, Skjønsberg OH, Larsen KO, Rostrup M (2022)
Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers
Physiol Rep, 10 (3), e15184
DOI 10.14814/phy2.15184, PubMed 35146955

Publications 2021

Heck SL, Mecinaj A, Ree AH, Hoffmann P, Schulz-Menger J, Fagerland MW, Gravdehaug B, Røsjø H, Steine K, Geisler J, Gulati G, Omland T (2021)
Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA): Extended Follow-Up of a 2×2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol
Circulation, 143 (25), 2431-2440
DOI 10.1161/CIRCULATIONAHA.121.054698, PubMed 33993702

Tøllefsen IM, Shetelig C, Seljeflot I, Eritsland J, Hoffmann P, Andersen GØ (2021)
High levels of interleukin-6 are associated with final infarct size and adverse clinical events in patients with STEMI
Open Heart, 8 (2)
DOI 10.1136/openhrt-2021-001869, PubMed 34933964

Publications 2020

Bergo KK, Larstorp AC, Hoffmann P, Hjørnholm U, Cataliotti A, Høieggen A, Rostrup M, Fadl Elmula FEM (2020)
Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension
Blood Press, 30 (1), 31-40
DOI 10.1080/08037051.2020.1789446, PubMed 32633141

Publications 2019

Al-Ani A, Hoffmann P, von Lueder T, Opdahl A (2019)
Safety and efficacy of hybrid vascular closure technique using both a suture- and collagen-mediated closure device after transfemoral transcatheter aortic valve implantation
Catheter Cardiovasc Interv, 95 (6), 1171-1175
DOI 10.1002/ccd.28419, PubMed 31379116

Helseth R, Shetelig C, Andersen GØ, Langseth MS, Limalanathan S, Opstad TB, Arnesen H, Hoffmann P, Eritsland J, Seljeflot I (2019)
Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI
Mediators Inflamm, 2019, 7816491
DOI 10.1155/2019/7816491, PubMed 31772506

Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Gonçalves I, Nilsson J, Grenegård M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2019)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625

Publications 2018

Bethke A, Shanmuganathan L, Andersen GØ, Eritsland J, Swanson D, Kløw NE, Hoffmann P (2018)
Microvascular perfusion in infarcted and remote myocardium after successful primary PCI: angiographic and CMR findings
Eur Radiol, 29 (2), 941-950
DOI 10.1007/s00330-018-5588-7, PubMed 29980929

Bethke A, Shanmuganathan L, Shetelig C, Swanson D, Andersen GØ, Eritsland J, Kløw NE, Hoffmann P (2018)
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI
PLoS One, 13 (11), e0206723
DOI 10.1371/journal.pone.0206723, PubMed 30412607

Heck SL, Gulati G, Hoffmann P, von Knobelsdorff-Brenkenhoff F, Storås TH, Ree AH, Gravdehaug B, Røsjø H, Steine K, Geisler J, Schulz-Menger J, Omland T (2018)
Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial
Eur Heart J Cardiovasc Imaging, 19 (5), 544-552
DOI 10.1093/ehjci/jex159, PubMed 29106497

Hoffmann P, Al-Ani A, von Lueder T, Hoffmann J, Majak P, Hagen O, Loose H, Kløw NE, Opdahl A (2018)
Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide
CVIR Endovasc, 1 (1), 20
DOI 10.1186/s42155-018-0026-0, PubMed 30652151

Hoffmann P, Al-Ani A, von Lueder T, Skoe ØW, Tran TT, Opdahl A (2018)
Late Pseudoaneurysm After Access Site Closure with Manta in Transfemoral Aortic Valve Implantation
EJVES Short Rep, 42, 34-36
DOI 10.1016/j.ejvssr.2018.10.003, PubMed 30931405

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279

Shetelig C, Limalanathan S, Hoffmann P, Seljeflot I, Gran JM, Eritsland J, Andersen GØ (2018)
Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI
J Am Coll Cardiol, 72 (2), 187-198
DOI 10.1016/j.jacc.2018.04.053, PubMed 29976293

Publications 2017

Gulati G, Heck SL, Røsjø H, Ree AH, Hoffmann P, Hagve TA, Norseth J, Gravdehaug B, Steine K, Geisler J, Omland T (2017)
Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study
J Am Heart Assoc, 6 (11)
DOI 10.1161/JAHA.117.006513, PubMed 29118031

Ritschel V, Shetelig C, Seljeflot I, Limalanathan S, Hoffmann P, Halvorsen S, Arnesen H, Eritsland J, Andersen GØ (2017)
Evaluation of circulating levels of CCN2/connective tissue growth factor in patients with ST-elevation myocardial infarction
Sci Rep, 7 (1), 11945
DOI 10.1038/s41598-017-12372-w, PubMed 28931920

Sanders MF, van Doormaal PJ, Beeftink MMA, Bots ML, Fadl Elmula FEM, Habets J, Hammer F, Hoffmann P, Jacobs L, Mark PB, Persu A, Renkin J, Roditi G, Spiering W, Staessen JA, Taylor AH, Verloop WL, Vink EE, Vonken EJ, Voskuil M, Leiner T, Blankestijn PJ, European Network COordinating research on Renal Denervation (ENCOReD) Consortium (2017)
Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography
Eur Radiol, 27 (9), 3934-3941
DOI 10.1007/s00330-017-4770-7, PubMed 28271154

Shetelig C, Limalanathan S, Eritsland J, Hoffmann P, Seljeflot I, Gran JM, Aukrust P, Ueland T, Andersen GØ (2017)
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034, PubMed 28253327

Publications 2016

Engblom H, Heiberg E, Erlinge D, Jensen SE, Nordrehaug JE, Dubois-Randé JL, Halvorsen S, Hoffmann P, Koul S, Carlsson M, Atar D, Arheden H (2016)
Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint
J Am Heart Assoc, 5 (3), e002708
DOI 10.1161/JAHA.115.002708, PubMed 26961520

Engblom H, Tufvesson J, Jablonowski R, Carlsson M, Aletras AH, Hoffmann P, Jacquier A, Kober F, Metzler B, Erlinge D, Atar D, Arheden H, Heiberg E (2016)
A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data
J Cardiovasc Magn Reson, 18 (1), 27
DOI 10.1186/s12968-016-0242-5, PubMed 27145749

Gulati G, Heck SL, Ree AH, Hoffmann P, Schulz-Menger J, Fagerland MW, Gravdehaug B, von Knobelsdorff-Brenkenhoff F, Bratland Å, Storås TH, Hagve TA, Røsjø H, Steine K, Geisler J, Omland T (2016)
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 × 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
Eur Heart J, 37 (21), 1671-80
DOI 10.1093/eurheartj/ehw022, PubMed 26903532

Nordlund D, Heiberg E, Carlsson M, Fründ ET, Hoffmann P, Koul S, Atar D, Aletras AH, Erlinge D, Engblom H, Arheden H (2016)
Extent of Myocardium at Risk for Left Anterior Descending Artery, Right Coronary Artery, and Left Circumflex Artery Occlusion Depicted by Contrast-Enhanced Steady State Free Precession and T2-Weighted Short Tau Inversion Recovery Magnetic Resonance Imaging
Circ Cardiovasc Imaging, 9 (7)
DOI 10.1161/CIRCIMAGING.115.004376, PubMed 27412659

Nordlund D, Klug G, Heiberg E, Koul S, Larsen TH, Hoffmann P, Metzler B, Erlinge D, Atar D, Aletras AH, Carlsson M, Engblom H, Arheden H (2016)
Multi-vendor, multicentre comparison of contrast-enhanced SSFP and T2-STIR CMR for determining myocardium at risk in ST-elevation myocardial infarction
Eur Heart J Cardiovasc Imaging, 17 (7), 744-53
DOI 10.1093/ehjci/jew027, PubMed 27002140

Publications 2015

Bethke A, Halvorsen S, Bøhmer E, Abdelnoor M, Arnesen H, Hoffmann P (2015)
Myocardial perfusion grade predicts final infarct size and left ventricular function in patients with ST-elevation myocardial infarction treated with a pharmaco-invasive strategy (thrombolysis and early angioplasty)
EuroIntervention, 11 (5), 518-24
DOI 10.4244/EIJY15M04_02, PubMed 25868877

Limalanathan S, Eritsland J, Kløw NE, Abdelnoor M, Hoffmann P, Andersen GØ (2015)
Influence of ischemic postconditioning on myocardial dysfunction measured by speckle tracking echocardiography in patients with ST-elevation myocardial infarction
Int J Cardiol, 187, 459-61
DOI 10.1016/j.ijcard.2015.03.192, PubMed 25846653

Publications 2014

Fadl Elmula FE, Hoffmann P, Larstorp AC, Fossum E, Brekke M, Kjeldsen SE, Gjønnæss E, Hjørnholm U, Kjaer VN, Rostrup M, Os I, Stenehjem A, Høieggen A (2014)
Adjusted drug treatment is superior to renal sympathetic denervation in patients with true treatment-resistant hypertension
Hypertension, 63 (5), 991-9
DOI 10.1161/HYPERTENSIONAHA.114.03246, PubMed 24591332

Helseth R, Solheim S, Opstad T, Hoffmann P, Arnesen H, Seljeflot I (2014)
The time profile of Pentraxin 3 in patients with acute ST-elevation myocardial infarction and stable angina pectoris undergoing percutaneous coronary intervention
Mediators Inflamm, 2014, 608414
DOI 10.1155/2014/608414, PubMed 24737925

Kjeldsen SE, Sørensen H, Fadl Elmula FE, Brekke M, Gjønnæss E, Hjørnholm U, Kjære VN, Rostrup M, Fossum E, Os I, Stenehjem A, Høieggen A, Hoffmann P (2014)
[Re: Renal sympathetic denervation in treatment-resistant hypertension]
Tidsskr Nor Laegeforen, 134 (15), 1449-50
DOI 10.4045/tidsskr.14.0931, PubMed 25138398

Limalanathan S, Andersen GØ, Kløw NE, Abdelnoor M, Hoffmann P, Eritsland J (2014)
Effect of ischemic postconditioning on infarct size in patients with ST-elevation myocardial infarction treated by primary PCI results of the POSTEMI (POstconditioning in ST-Elevation Myocardial Infarction) randomized trial
J Am Heart Assoc, 3 (2), e000679
DOI 10.1161/JAHA.113.000679, PubMed 24760962

Mariampillai JE, Fadl Elmula FE, Hoffmann P, Sørensen H, Høieggen A, Kjeldsen SE (2014)
[Questionable efficacy of renal denervation]
Tidsskr Nor Laegeforen, 134 (17), 1643-4
DOI 10.4045/tidsskr.14.0900, PubMed 25223668

Njerve IU, Solheim S, Lunde K, Hoffmann P, Arnesen H, Seljeflot I (2014)
Fractalkine levels are elevated early after PCI-treated ST-elevation myocardial infarction; no influence of autologous bone marrow derived stem cell injection
Cytokine, 69 (1), 131-5
DOI 10.1016/j.cyto.2014.05.022, PubMed 24930044

Sørensen H, Fadl Elmula FE, Kjeldsen SE, Brekke M, Gjønnæss E, Hjørnholm U, Kjær VN, Rostrup M, Fossum E, Os I, Stenehjem A, Høieggen A, Hoffmann P (2014)
[Renal sympathetic denervation in treatment-resistant hypertension]
Tidsskr Nor Laegeforen, 134 (1), 32-6
DOI 10.4045/tidsskr.13.0276, PubMed 24429753

Publications 2013

Fadl Elmula FE, Hoffmann P, Fossum E, Brekke M, Gjønnæss E, Hjørnholm U, Kjær VN, Rostrup M, Kjeldsen SE, Os I, Stenehjem AE, Høieggen A (2013)
Renal sympathetic denervation in patients with treatment-resistant hypertension after witnessed intake of medication before qualifying ambulatory blood pressure
Hypertension, 62 (3), 526-32
DOI 10.1161/HYPERTENSIONAHA.113.01452, PubMed 23836798

Gulati G, Heck SL, Ree AH, Gravdehaug B, Røsjø H, Steine K, Bratland Å, Hoffmann P, Geisler J, Omland T (2013)
[Cardioprotective treatment during adjuvant cancer therapy]
Tidsskr Nor Laegeforen, 133 (17), 1832-6
DOI 10.4045/tidsskr.12.1514, PubMed 24042297

Limalanathan S, Eritsland J, Andersen GØ, Kløw NE, Abdelnoor M, Hoffmann P (2013)
Myocardial salvage is reduced in primary PCI-treated STEMI patients with microvascular obstruction, demonstrated by early and late CMR
PLoS One, 8 (8), e71780
DOI 10.1371/journal.pone.0071780, PubMed 23977143

Publications 2012

Heck SL, Gulati G, Ree AH, Schulz-Menger J, Gravdehaug B, Røsjø H, Steine K, Bratland A, Hoffmann P, Geisler J, Omland T (2012)
Rationale and design of the prevention of cardiac dysfunction during an Adjuvant Breast Cancer Therapy (PRADA) Trial
Cardiology, 123 (4), 240-7
DOI 10.1159/000343622, PubMed 23207160

Publications 2011

Grøgaard HK, Solheim S, Landsverk KS, Seljeflot I, Hoffmann P, Arnesen H, Ilebekk A (2011)
Circulating CD34⁺ progenitor cells and growth factors in patients treated with PCI for acute myocardial infarction or stable angina pectoris
Scand J Clin Lab Invest, 71 (4), 322-9
DOI 10.3109/00365513.2011.565367, PubMed 21463159

Mistry N, Abdelnoor M, Seljeflot I, Hoffmann P, Bøhmer E, Bjørnerheim R, Kjeldsen SE, Halvorsen S (2011)
Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels 3 months after myocardial infarction are more strongly associated with magnetic resonance-determined ejection fraction than NTproBNP levels in the acute phase
J Card Fail, 17 (6), 479-86
DOI 10.1016/j.cardfail.2011.02.006, PubMed 21624736

Mistry N, Beitnes JO, Halvorsen S, Abdelnoor M, Hoffmann P, Kjeldsen SE, Smith G, Aakhus S, Bjørnerheim R (2011)
Assessment of left ventricular function in ST-elevation myocardial infarction by global longitudinal strain: a comparison with ejection fraction, infarct size, and wall motion score index measured by non-invasive imaging modalities
Eur J Echocardiogr, 12 (9), 678-83
DOI 10.1093/ejechocard/jer113, PubMed 21810829

Stensaeth KH, Hoffmann P, Fossum E, Mangschau A, Sandvik L, Klow NE (2011)
Cardiac magnetic resonance visualizes acute and chronic myocardial injuries in myocarditis
Int J Cardiovasc Imaging, 28 (2), 327-35
DOI 10.1007/s10554-011-9812-7, PubMed 21347598

Publications 2010

Bøhmer E, Seljeflot I, Arnesen H, Hoffmann P, Abdelnoor M, Halvorsen S (2010)
The association between metabolic syndrome and infarct size in patients with acute myocardial infarction
Scand J Clin Lab Invest, 70 (4), 287-93
DOI 10.3109/00365513.2010.481819, PubMed 20429699

Limalanathan S, Andersen GØ, Hoffmann P, Kløw NE, Abdelnoor M, Eritsland J (2010)
Rationale and design of the POSTEMI (postconditioning in ST-elevation myocardial infarction) study
Cardiology, 116 (2), 103-9
DOI 10.1159/000316965, PubMed 20588018

Mistry N, Bøhmer E, Hoffmann P, Müller C, Bjørnerheim R, Kjeldsen SE, Halvorsen S (2010)
Left ventricular function in acute myocardial infarction treated with thrombolysis followed by early versus late invasive strategy
Am Heart J, 160 (1), 73-9
DOI 10.1016/j.ahj.2010.04.011, PubMed 20598975

Mistry N, Halvorsen S, Hoffmann P, Müller C, Bøhmer E, Kjeldsen SE, Bjørnerheim R (2010)
Assessment of left ventricular function with magnetic resonance imaging vs. echocardiography, contrast echocardiography, and single-photon emission computed tomography in patients with recent ST-elevation myocardial infarction
Eur J Echocardiogr, 11 (9), 793-800
DOI 10.1093/ejechocard/jeq069, PubMed 20525984

Stensæth KH, Fossum E, Hoffmann P, Mangschau A, Skretteberg PT, Kløw NE (2010)
Takotsubo cardiomyopathy in acute coronary syndrome; clinical features and contribution of cardiac magnetic resonance during the acute and convalescent phase
Scand Cardiovasc J, 45 (2), 77-85
DOI 10.3109/14017431.2010.531140, PubMed 20979536

Publications 2009

Bøhmer E, Hoffmann P, Abdelnoor M, Arnesen H, Halvorsen S (2009)
Efficacy and safety of immediate angioplasty versus ischemia-guided management after thrombolysis in acute myocardial infarction in areas with very long transfer distances results of the NORDISTEMI (NORwegian study on DIstrict treatment of ST-elevation myocardial infarction)
J Am Coll Cardiol, 55 (2), 102-10
DOI 10.1016/j.jacc.2009.08.007, PubMed 19747792

Bøhmer E, Hoffmann P, Abdelnoor M, Seljeflot I, Halvorsen S (2009)
Troponin T concentration 3 days after acute ST-elevation myocardial infarction predicts infarct size and cardiac function at 3 months
Cardiology, 113 (3), 207-12
DOI 10.1159/000201991, PubMed 19218804

Furenes EB, Arnesen H, Solheim S, Grøgaard HK, Hoffmann P, Seljeflot I (2009)
The profile of circulating metalloproteinases after PCI in patients with acute myocardial infarction or stable angina
Thromb Res, 124 (5), 560-4
DOI 10.1016/j.thromres.2009.04.001, PubMed 19410278

Publications 2007

Bøhmer E, Arnesen H, Abdelnoor M, Mangschau A, Hoffmann P, Halvorsen S (2007)
The NORwegian study on DIstrict treatment of ST-elevation myocardial infarction (NORDISTEMI)
Scand Cardiovasc J, 41 (1), 32-8
DOI 10.1080/14017430601153472, PubMed 17365975

Publications 2006

Hoffmann P, Halvorsen S, Stensaeth KH, Brekke M, Müller C, Anker GO, Abdelnoor M, Kløw NE (2006)
Myocardial perfusion in ST-elevation myocardial infarction treated successfully with primary angioplasty
Scand Cardiovasc J, 40 (2), 96-104
DOI 10.1080/14017430600628144, PubMed 16608779

Publications 2004

Undseth RM, Kløw NE, Hoffmann P (2004)
[Treatment of pseudoaneurysms after vascular interventions]
Tidsskr Nor Laegeforen, 124 (10), 1384-6
PubMed 15195176