Pavel Hoffmann

  • Consultant; MD, PhD
 

Publications 2021

Bergo KK, Larstorp AC, Hoffmann P, Hjornholm U, Cataliotti A, Hoieggen A, Rostrup M, Elmula FEMF (2021)
Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension
Blood Pressure, 30 (1), 31-40
DOI 10.1080/08037051.2020.1789446

Heck SL, Mecinaj A, Ree AH, Hoffmann P, Schulz-Menger J, Fagerland MW, Gravdehaug B, Rosjo H, Steine K, Geisler J, Gulati G, Omland T (2021)
Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) Extended Follow-Up of a 2x2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol
Circulation, 143 (25), 2431-2440
DOI 10.1161/CIRCULATIONAHA.121.054698

Tollefsen IM, Shetelig C, Seljeflot I, Eritsland J, Hoffmann P, Andersen GO (2021)
High levels of interleukin-6 are associated with final infarct size and adverse clinical events in patients with STEMI
Open Heart, 8 (2), e001869
DOI 10.1136/openhrt-2021-001869

Publications 2020

Al-Ani A, Hoffmann P, von Lueder T, Opdahl A (2020)
Safety and efficacy of hybrid vascular closure technique using both a suture- and collagen-mediated closure device after transfemoral transcatheter aortic valve implantation
Catheter. Cardiovasc. Interv., 95 (6), 1171-1175
DOI 10.1002/ccd.28419

Lunde NN, Gregersen I, Ueland T, Shetelig C, Holm S, Kong XY, Michelsen AE, Otterdal K, Yndestad A, Broch K, Gullestad L, Nyman TA, Bendz B, Eritsland J, Hoffmann P, Skagen K, Goncalves I, Nilsson J, Grenegard M, Poreba M, Drag M, Seljeflot I, Sporsheim B, Espevik T, Skjelland M et al. (2020)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008

Publications 2019

Bethke A, Shanmuganathan L, Andersen GO, Eritsland J, Swanson D, Klow NE, Hoffmann P (2019)
Microvascular perfusion in infarcted and remote myocardium after successful primary PCI: angiographic and CMR findings
Eur. Radiol., 29 (2), 941-950
DOI 10.1007/s00330-018-5588-7

Helseth R, Shetelig C, Andersen GO, Langseth MS, Limalanathan S, Opstad TB, Arnesen H, Hoffmann P, Eritsland J, Seljeflot I (2019)
Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI
Mediat. Inflamm., 2019, 7816491
DOI 10.1155/2019/7816491

Publications 2018

Bethke A, Shanmuganathan L, Shetelig C, Swanson D, Andersen GO, Eritsland J, Klow NE, Hoffmann P (2018)
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI
PLoS One, 13 (11), e0206723
DOI 10.1371/journal.pone.0206723

Heck SL, Gulati G, Hoffmann P, von Knobelsdorff-Brenkenhoff F, Storas TH, Ree AH, Gravdehaug B, Rosjo H, Steine K, Geisler J, Schulz-Menger J, Omland T (2018)
Effect of candesartan and metoprolol on myocardial tissue composition during anthracycline treatment: the PRADA trial
Eur. Heart J.-Cardiovasc. Imaging, 19 (5), 544-552
DOI 10.1093/ehjci/jex159

Hoffmann P, Al-Ani A, von Lueder T, Hoffmann J, Majak P, Hagen O, Loose H, Klow NE, Opdahl A (2018)
Access site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide
CVIR Endovasc., 1 (1), 20
DOI 10.1186/s42155-018-0026-0

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GO, Yndestad A (2018)
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int. J. Cardiol., 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032

Shetelig C, Limalanathan S, Hoffmann P, Seljeflot I, Gran JM, Eritsland J, Andersen GO (2018)
Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI
J. Am. Coll. Cardiol., 72 (2), 187-198
DOI 10.1016/j.jacc.2018.04.053

Publications 2017

Gulati G, Heck SL, Rosjo H, Ree AH, Hoffmann P, Hagve TA, Norseth J, Gravdehaug B, Steine K, Geisler J, Omland T (2017)
Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study
J. Am. Heart Assoc., 6 (11)
DOI 10.1161/JAHA.117.006513

Ritschel V, Shetelig C, Seljeflot I, Limalanathan S, Hoffmann P, Halvorsen S, Arnesen H, Eritsland J, Andersen GO (2017)
Evaluation of circulating levels of CCN2/connective tissue growth factor in patients with ST-elevation myocardial infarction
Sci Rep, 7, 11945
DOI 10.1038/s41598-017-12372-w

Sanders MF, van Doormaal PJ, Beeftink MMA, Bots ML, Elmula MF, Habets J, Hammer F, Hoffmann P, Jacobs L, Mark PB, Persu A, Renkin J, Roditi G, Spiering W, Staessen JA, Taylor AH, Verloop WL, Vink EE, Vonken EJ, Voskuil M, Leiner T, Blankestijn PJ, European Network COordinating Res (2017)
Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography
Eur. Radiol., 27 (9), 3934-3941
DOI 10.1007/s00330-017-4770-7

Shetelig C, Limalanathan S, Eritsland J, Hoffmann P, Seljeflot I, Gran JM, Aukrust P, Ueland T, Andersen GO (2017)
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034

Publications 2016

Engblom H, Heiberg E, Erlinge D, Jensen SE, Nordrehaug JE, Dubois-Rande JL, Halvorsen S, Hoffmann P, Koul S, Carlsson M, Atar D, Arheden H (2016)
Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint
J. Am. Heart Assoc., 5 (3), e002708
DOI 10.1161/JAHA.115.002708

Engblom H, Tufvesson J, Jablonowski R, Carlsson M, Aletras AH, Hoffmann P, Jacquier A, Kober F, Metzler B, Erlinge D, Atar D, Arheden H, Heiberg E (2016)
A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data
J. Cardiov. Magn. Reson., 18, 27
DOI 10.1186/s12968-016-0242-5

Gulati G, Heck SL, Ree AH, Hoffmann P, Schulz-Menger J, Fagerland MW, Gravdehaug B, von Knobelsdorff-Brenkenhoff F, Bratland A, Storas TH, Hagve TA, Rosjo H, Steine K, Geisler J, Omland T (2016)
Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2 x 2 factorial, randomized, placebo-controlled, double-blind clinical trial of candesartan and metoprolol
Eur. Heart J., 37 (21), 1671-1680
DOI 10.1093/eurheartj/ehw022

Nordlund D, Heiberg E, Carlsson M, Frund ET, Hoffmann P, Koul S, Atar D, Aletras AH, Erlinge D, Engblom H, Arheden H (2016)
Extent of Myocardium at Risk for Left Anterior Descending Artery, Right Coronary Artery, and Left Circumflex Artery Occlusion Depicted by Contrast-Enhanced Steady State Free Precession and T2-Weighted Short Tau Inversion Recovery Magnetic Resonance Imaging
Circ.-Cardiovasc. Imaging, 9 (7), e004376
DOI 10.1161/CIRCIMAGING.115.004376

Nordlund D, Klug G, Heiberg E, Koul S, Larsen TH, Hoffmann P, Metzler B, Erlinge D, Atar D, Aletras AH, Carlsson M, Engblom H, Arheden H (2016)
Multi-vendor, multicentre comparison of contrast-enhanced SSFP and T2-STIR CMR for determining myocardium at risk in ST-elevation myocardial infarction
Eur. Heart J.-Cardiovasc. Imaging, 17 (7), 744-753
DOI 10.1093/ehjci/jew027

Publications 2015

Bethke A, Halvorsen S, Bohmer E, Abdelnoor M, Arnesen H, Hoffmann P (2015)
Myocardial perfusion grade predicts final infarct size and left ventricular function in patients with ST-elevation myocardial infarction treated with a pharmaco-invasive strategy (thrombolysis and early angioplasty)
EuroIntervention, 11 (5), 518-524

Limalanathan S, Eritsland J, Klow NE, Abdelnoor M, Hoffmann P, Andersen GO (2015)
Influence of ischemic postconditioning on myocardial dysfunction measured by speckle tracking echocardiography in patients with ST-elevation myocardial infarction
Int. J. Cardiol., 187, 459-461
DOI 10.1016/j.ijcard.2015.03.192

Publications 2014

Elmula FEMF, Hoffmann P, Larstorp AC, Fossum E, Brekke M, Kjeldsen SE, Gjonnaess E, Hjornholm U, Kjaer VN, Rostrup M, Os I, Stenehjem A, Hoieggen A (2014)
Adjusted Drug Treatment Is Superior to Renal Sympathetic Denervation in Patients With True Treatment-Resistant Hypertension
Hypertension, 63 (5), 991-999
DOI 10.1161/HYPERTENSIONAHA.114.03246

Helseth R, Solheim S, Opstad T, Hoffmann P, Arnesen H, Seljeflot I (2014)
The Time Profile of Pentraxin 3 in Patients with Acute ST-Elevation Myocardial Infarction and Stable Angina Pectoris Undergoing Percutaneous Coronary Intervention
Mediat. Inflamm., 2014, 608414
DOI 10.1155/2014/608414

Limalanathan S, Andersen GO, Klow NE, Abdelnoor M, Hoffmann P, Eritsland J (2014)
Effect of Ischemic Postconditioning on Infarct Size in Patients With ST-Elevation Myocardial Infarction Treated by Primary PCI Results of the POSTEMI (POstconditioning in ST-Elevation Myocardial Infarction) Randomized Trial
J. Am. Heart Assoc., 3 (2), e000679
DOI 10.1161/JAHA.113.000679

Njerve IU, Solheim S, Lunde K, Hoffmann P, Arnesen H, Seljeflot I (2014)
Fractalkine levels are elevated early after PCI-treated ST-elevation myocardial infarction; no influence of autologous bone marrow derived stem cell injection
Cytokine, 69 (1), 131-135
DOI 10.1016/j.cyto.2014.05.022

Publications 2013

Elmula FEMF, Hoffmann P, Fossum E, Brekke M, Gjonnaess E, Hjornholm U, Kjaer VN, Rostrup M, Kjeldsen SE, Os I, Stenehjem AE, Hoieggen A (2013)
Renal Sympathetic Denervation in Patients With Treatment-Resistant Hypertension After Witnessed Intake of Medication Before Qualifying Ambulatory Blood Pressure
Hypertension, 62 (3), 526-532
DOI 10.1161/HYPERTENSIONAHA.113.01452

Limalanathan S, Eritsland J, Andersen GO, Klow NE, Abdelnoor M, Hoffmann P (2013)
Myocardial Salvage is Reduced in Primary PCI-Treated STEMI Patients with Microvascular Obstruction, Demonstrated by Early and Late CMR
PLoS One, 8 (8), e71780
DOI 10.1371/journal.pone.0071780

Publications 2012

Heck SL, Gulati G, Ree AH, Schulz-Menger J, Gravdehaug B, Rosjo H, Steine K, Bratland A, Hoffmann P, Geisler J, Omland T (2012)
Rationale and Design of the Prevention of Cardiac Dysfunction during an Adjuvant Breast Cancer Therapy (PRADA) Trial
Cardiology, 123 (4), 240-247
DOI 10.1159/000343622

Stensaeth KH, Hoffmann P, Fossum E, Mangschau A, Sandvik L, Klow NE (2012)
Cardiac magnetic resonance visualizes acute and chronic myocardial injuries in myocarditis
Int. J. Cardiovasc. Imaging, 28 (2), 327-335
DOI 10.1007/s10554-011-9812-7

Publications 2011

Grogaard HK, Solheim S, Landsverk KS, Seljeflot I, Hoffmann P, Arnesen H, Ilebekk A (2011)
Circulating CD34(+) progenitor cells and growth factors in patients treated with PCI for acute myocardial infarction or stable angina pectoris
Scand. J. Clin. Lab. Invest., 71 (4), 322-329
DOI 10.3109/00365513.2011.565367

Mistry N, Abdelnoor M, Seljeflot I, Hoffmann P, Bohmer E, Bjornerheim R, Kjeldsen SE, Halvorsen S (2011)
Amino-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP) Levels 3 Months After Myocardial Infarction Are More Strongly Associated With Magnetic Resonance-Determined Ejection Fraction Than NTproBNP Levels in the Acute Phase
J. Card. Fail., 17 (6), 479-486
DOI 10.1016/j.cardfail.2011.02.006

Mistry N, Beitnes JO, Halvorsen S, Abdelnoor M, Hoffmann P, Kjeldsen SE, Smith G, Aakhus S, Bjornerheim R (2011)
Assessment of left ventricular function in ST-elevation myocardial infarction by global longitudinal strain: a comparison with ejection fraction, infarct size, and wall motion score index measured by non-invasive imaging modalities
Eur. J. Echocardiogr., 12 (9), 678-683
DOI 10.1093/ejechocard/jer113

Stensaeth KH, Fossum E, Hoffmann P, Mangschau A, Skretteberg PT, Klow NE (2011)
Takotsubo cardiomyopathy in acute coronary syndrome; clinical features and contribution of cardiac magnetic resonance during the acute and convalescent phase
Scand. Cardiovasc. J., 45 (2), 77-85
DOI 10.3109/14017431.2010.531140

Publications 2010

Bohmer E, Hoffmann P, Abdelnoor M, Arnesen H, Halvorsen S (2010)
Efficacy and Safety of Immediate Angioplasty Versus Ischemia-Guided Management After Thrombolysis in Acute Myocardial Infarction in Areas With Very Long Transfer Distances Results of the NORDISTEMI (NORwegian study on DIstrict treatment of ST-Elevation Myocardial Infarction)
J. Am. Coll. Cardiol., 55 (2), 102-110
DOI 10.1016/j.jacc.2009.08.007

Bohmer E, Seljeflot I, Arnesen H, Hoffmann P, Abdelnoor M, Halvorsen S (2010)
The association between metabolic syndrome and infarct size in patients with acute myocardial infarction
Scand. J. Clin. Lab. Invest., 70 (4), 287-293
DOI 10.3109/00365513.2010.481819

Limalanathan S, Andersen GO, Hoffmann P, Klow NE, Abdelnoor M, Eritsland J (2010)
Rationale and Design of the POSTEMI (Postconditioning in ST-Elevation Myocardial Infarction) Study
Cardiology, 116 (2), 103-109
DOI 10.1159/000316965

Mistry N, Bohmer E, Hoffmann P, Muller C, Bjornerheim R, Kjeldsen SE, Halvorsen S (2010)
Left ventricular function in acute myocardial infarction treated with thrombolysis followed by early versus late invasive strategy
Am. Heart J., 160 (1), 73-79
DOI 10.1016/j.ahj.2010.04.011

Mistry N, Halvorsen S, Hoffmann P, Muller C, Bohmer E, Kjeldsen SE, Bjornerheim R (2010)
Assessment of left ventricular function with magnetic resonance imaging vs. echocardiography, contrast echocardiography, and single-photon emission computed tomography in patients with recent ST-elevation myocardial infarction
Eur. J. Echocardiogr., 11 (9), 793-800
DOI 10.1093/ejechocard/jeq069

Publications 2009

Bohmer E, Hoffmann P, Abdelnoor M, Seljeflot I, Halvorsen S (2009)
Troponin T Concentration 3 Days after Acute ST-Elevation Myocardial Infarction Predicts Infarct Size and Cardiac Function at 3 Months
Cardiology, 113 (3), 207-212
DOI 10.1159/000201991

Furenes EB, Arnesen H, Solheim S, Grogaard HK, Hoffmann P, Seljeflot I (2009)
The profile of circulating metalloproteinases after PCI in patients with acute myocardial infarction or stable angina
Thromb. Res., 124 (5), 560-564
DOI 10.1016/j.thromres.2009.04.001

Publications 2007

Bohmer E, Arnesen H, Abdelnoor M, Mangschau A, Hoffmann P, Halvorsen S (2007)
The NORwegian study on DIstrict treatment of ST-elevation myocardial infarction (NORDISTEMI)
Scand. Cardiovasc. J., 41 (1), 32-38
DOI 10.1080/14017430601153472