Publications 2024

Dietze LMF, McWhinney SR, Favre P, Abé C, Alexander N, Barkhau C, Benedetti F, Berk M, Bøen E, Boye B, Brosch K, Canales-Rodríguez EJ, Cannon DM, Carruthers SP, Corkum ELV, Dannlowski U, Díaz-Zuluaga AM, Dohm K, Elvsåshagen T, Flinkenflügel K, Fortea L, Furlong LS, Goldstein BI, Grotegerd D, Gruber M et al. (2024)
White matter microstructure in obesity and bipolar disorders: an ENIGMA bipolar disorder working group study in 2186 individuals
Mol Psychiatry (in press)
DOI 10.1038/s41380-024-02784-2, PubMed 39501059

McWhinney SR, Hlinka J, Bakstein E, Dietze LMF, Corkum ELV, Abé C, Alda M, Alexander N, Benedetti F, Berk M, Bøen E, Bonnekoh LM, Boye B, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Demro C, Diaz-Zuluaga A, Elvsåshagen T, Eyler LT, Fortea L, Fullerton JM, Goltermann J, Gotlib IH et al. (2024)
Principal component analysis as an efficient method for capturing multivariate brain signatures of complex disorders-ENIGMA study in people with bipolar disorders and obesity
Hum Brain Mapp, 45 (8), e26682
DOI 10.1002/hbm.26682, PubMed 38825977

Serranová T, Di Vico I, Tinazzi M, Aybek S, Bilic E, Binzer S, Bøen E, Bruggeman A, Bratanov C, Cabreira VRA, Golder D, Dunalska A, Falup-Pecurariu C, Garcin B, Gelauff J, Laffan A, Podnar S, Pareés I, Plender T, Popkirov S, Romanenko V, Schwingenschuh P, Seliverstov Y, Sjöström C, Škorvánek M et al. (2024)
Functional neurological disorder in Europe: regional differences in education and health policy
Eur J Neurol, 31 (10), e16350
DOI 10.1111/ene.16350, PubMed 39145716

Publications 2023

McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Diaz-Zuluaga AM, Dietze LMF, Elvsåshagen T, Eyler LT, Fullerton JM, Goikolea JM, Goltermann J, Grotegerd D, Haarman BCM, Hahn T, Howells FM, Ingvar M, Jahanshad N, Kircher TTJ et al. (2023)
Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants
Psychol Med, 53 (14), 6743-6753
DOI 10.1017/S0033291723000223, PubMed 36846964

Zak N, Moberget T, Bøen E, Boye B, Rygvold TW, Malt UF, Andreassen OA, Andersson S, Westlye LT, Elvsåshagen T (2023)
Baseline long-term potentiation-like cortical plasticity is associated with longitudinal cortical thinning in healthy adults and in adults with bipolar disorder type II
Eur J Neurosci, 58 (3), 2824-2837
DOI 10.1111/ejn.16038, PubMed 37163975

Publications 2022

Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, Alloza C, Alnæs D, Artiges E, Ayesa-Arriola R, Barker GJ, Bastin ME, Blok E, Bøen E, Breukelaar IA, Bright JK et al. (2022)
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Nat Neurosci, 25 (4), 421-432
DOI 10.1038/s41593-022-01042-4, PubMed 35383335

Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169

Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530

Voldsbekk I, Bjørnerud A, Groote I, Zak N, Roelfs D, Maximov II, Geier O, Due-Tønnessen P, Bøen E, Kuiper YS, Løkken LL, Strømstad M, Blakstvedt TY, Bjorvatn B, Malt UF, Westlye LT, Elvsåshagen T, Grydeland H (2022)
Evidence for widespread alterations in cortical microstructure after 32 h of sleep deprivation
Transl Psychiatry, 12 (1), 161
DOI 10.1038/s41398-022-01909-x, PubMed 35422097

Publications 2021

Abé C, Ching CRK, Liberg B, Lebedev AV, Agartz I, Akudjedu TN, Alda M, Alnæs D, Alonso-Lana S, Benedetti F, Berk M, Bøen E, Bonnin CDM, Breuer F, Brosch K, Brouwer RM, Canales-Rodríguez EJ, Cannon DM, Chye Y, Dahl A, Dandash O, Dannlowski U, Dohm K, Elvsåshagen T, Fisch L et al. (2021)
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987

Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I (2021)
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
DOI 10.1017/S0033291721003056, PubMed 35387700

McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Diaz-Zuluaga AM, Dietze L, Elvsåshagen T, Eyler LT, Fullerton JM, Goikolea JM, Goltermann J, Grotegerd D, Haarman BCM, Hahn T, Howells FM, Ingvar M, Kircher TTJ, Krug A et al. (2021)
Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals
Bipolar Disord, 24 (5), 509-520
DOI 10.1111/bdi.13172, PubMed 34894200

McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Díaz-Zuluaga AM, Elvsåshagen T, Eyler LT, Fullerton JM, Goikolea JM, Goltermann J, Grotegerd D, Haarman BCM, Hahn T, Howells FM, Ingvar M, Kircher TTJ, Krug A, Kuplicki RT et al. (2021)
Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals
Mol Psychiatry, 26 (11), 6806-6819
DOI 10.1038/s41380-021-01098-x, PubMed 33863996

Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH et al. (2021)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
DOI 10.1038/s41588-021-00857-4, PubMed 34002096

Pham U, Skogseid IM, Pripp AH, Bøen E, Toft M (2021)
Impulsivity in Parkinson's disease patients treated with subthalamic nucleus deep brain stimulation-An exploratory study
PLoS One, 16 (3), e0248568
DOI 10.1371/journal.pone.0248568, PubMed 33711081

Røssberg JI, Evensen J, Dammen T, Wilberg T, Klungsøyr O, Jones M, Bøen E, Egeland R, Breivik R, Løvgren A, Ulberg R (2021)
Mechanisms of change and heterogeneous treatment effects in psychodynamic and cognitive behavioural therapy for patients with depressive disorder: a randomized controlled trial
BMC Psychol, 9 (1), 11
DOI 10.1186/s40359-021-00517-6, PubMed 33482927

Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379

Publications 2020

Bøen E, Hummelen B, Boye B, Elvsåshagen T, Malt UF (2020)
Borderline patients have difficulties describing feelings; bipolar II patients describe difficult feelings. An alexithymia study
Acta Psychiatr Scand, 142 (3), 203-214
DOI 10.1111/acps.13204, PubMed 32594515

Ching CRK, Hibar DP, Gurholt TP, Nunes A, Thomopoulos SI, Abé C, Agartz I, Brouwer RM, Cannon DM, de Zwarte SMC, Eyler LT, Favre P, Hajek T, Haukvik UK, Houenou J, Landén M, Lett TA, McDonald C, Nabulsi L, Patel Y, Pauling ME, Paus T, Radua J, Soeiro-de-Souza MG, Tronchin G et al. (2020)
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849

Drange OK, Sæther SG, Finseth PI, Morken G, Vaaler AE, Arntsen V, Henning O, Andreassen OA, Elvsåshagen T, Malt UF, Bøen E (2020)
Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study
BMC Psychiatry, 20 (1), 582
DOI 10.1186/s12888-020-02968-4, PubMed 33287748

Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, Coynel D, Di Carlo P, Djurovic S, Eisenacher S, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B et al. (2020)
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260

Han LKM, Dinga R, Hahn T, Ching CRK, Eyler LT, Aftanas L, Aghajani M, Aleman A, Baune BT, Berger K, Brak I, Filho GB, Carballedo A, Connolly CG, Couvy-Duchesne B, Cullen KR, Dannlowski U, Davey CG, Dima D, Duran FLS, Enneking V, Filimonova E, Frenzel S, Frodl T, Fu CHY et al. (2020)
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Mol Psychiatry, 26 (9), 5124-5139
DOI 10.1038/s41380-020-0754-0, PubMed 32424236

Haukvik UK, Gurholt TP, Nerland S, Elvsåshagen T, Akudjedu TN, Alda M, Alnaes D, Alonso-Lana S, Bauer J, Baune BT, Benedetti F, Berk M, Bettella F, Bøen E, Bonnín CM, Brambilla P, Canales-Rodríguez EJ, Cannon DM, Caseras X, Dandash O, Dannlowski U, Delvecchio G, Díaz-Zuluaga AM, van Erp TGM, Fatjó-Vilas M et al. (2020)
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2020)
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485

Publications 2019

Bøen E, Hjørnevik T, Hummelen B, Elvsåshagen T, Moberget T, Holtedahl JE, Babovic A, Hol PK, Karterud S, Malt UF (2019)
Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder
Acta Psychiatr Scand, 139 (3), 256-268
DOI 10.1111/acps.12997, PubMed 30552759

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2019)
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603

Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A et al. (2019)
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
DOI 10.1038/s41588-019-0397-8, PubMed 31043756

Zak N, Bøen E, Boye B, Andreassen OA, Doan NT, Malt UF, Westlye LT, Elvsåshagen T (2019)
Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II
Bipolar Disord, 21 (6), 525-538
DOI 10.1111/bdi.12771, PubMed 30864260

Publications 2018

Nunes A, Schnack HG, Ching CRK, Agartz I, Akudjedu TN, Alda M, Alnæs D, Alonso-Lana S, Bauer J, Baune BT, Bøen E, Bonnin CDM, Busatto GF, Canales-Rodríguez EJ, Cannon DM, Caseras X, Chaim-Avancini TM, Dannlowski U, Díaz-Zuluaga AM, Dietsche B, Doan NT, Duchesnay E, Elvsåshagen T, Emden D, Eyler LT et al. (2018)
Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
DOI 10.1038/s41380-018-0228-9, PubMed 30171211

Zak N, Moberget T, Bøen E, Boye B, Waage TR, Dietrichs E, Harkestad N, Malt UF, Westlye LT, Andreassen OA, Andersson S, Elvsåshagen T (2018)
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals
Transl Psychiatry, 8 (1), 103
DOI 10.1038/s41398-018-0151-5, PubMed 29795193

Publications 2017

Hibar DP, Westlye LT, Doan NT, Jahanshad N, Cheung JW, Ching CRK, Versace A, Bilderbeck AC, Uhlmann A, Mwangi B, Krämer B, Overs B, Hartberg CB, Abé C, Dima D, Grotegerd D, Sprooten E, Bøen E, Jimenez E, Howells FM, Delvecchio G, Temmingh H, Starke J, Almeida JRC, Goikolea JM et al. (2017)
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Mol Psychiatry, 23 (4), 932-942
DOI 10.1038/mp.2017.73, PubMed 28461699

Publications 2016

Bøen E (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (2), 158
DOI 10.4045/tidsskr.15.1220, PubMed 26813829

Elvsåshagen T, Zuzarte P, Westlye LT, Bøen E, Josefsen D, Boye B, Hol PK, Malt UF, Young LT, Andreazza AC (2016)
Dentate gyrus-cornu ammonis (CA) 4 volume is decreased and associated with depressive episodes and lipid peroxidation in bipolar II disorder: Longitudinal and cross-sectional analyses
Bipolar Disord, 18 (8), 657-668
DOI 10.1111/bdi.12457, PubMed 27995733

Hibar DP, Westlye LT, van Erp TG, Rasmussen J, Leonardo CD, Faskowitz J, Haukvik UK, Hartberg CB, Doan NT, Agartz I, Dale AM, Gruber O, Krämer B, Trost S, Liberg B, Abé C, Ekman CJ, Ingvar M, Landén M, Fears SC, Freimer NB, Bearden CE, Costa Rica/Colombia Consortium for Genetic Investigation of Bipolar Endophenotypes, Sprooten E, Glahn DC et al. (2016)
Subcortical volumetric abnormalities in bipolar disorder
Mol Psychiatry, 21 (12), 1710-1716
DOI 10.1038/mp.2015.227, PubMed 26857596

Publications 2015

Lövdahl H, Bøen E, Malt EA, Malt UF (2015)
Erratum to "Somatic and cognitive symptoms as indicators of potential endophenotypes in bipolar spectrum disorders: An exploratory and proof-of-concept study comparing bipolar II disorder with recurrent brief depression and healthy controls" [J. Affect. Disord. 166 (2014) 59-70]
J Affect Disord, 175, 217-217
DOI 10.1016/j.jad.2014.10.011, PubMed 25645701

Publications 2014

Bøen E, Hummelen B, Elvsåshagen T, Boye B, Andersson S, Karterud S, Malt UF (2014)
Different impulsivity profiles in borderline personality disorder and bipolar II disorder
J Affect Disord, 170, 104-11
DOI 10.1016/j.jad.2014.08.033, PubMed 25237733

Bøen E, Westlye LT, Elvsåshagen T, Hummelen B, Hol PK, Boye B, Andersson S, Karterud S, Malt UF (2014)
Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder
J Psychiatry Neurosci, 39 (2), 127-34
DOI 10.1503/jpn.130070, PubMed 24309162

Elvsåshagen T, Moberget T, Bøen E, Hol PK, Malt UF, Andersson S, Westlye LT (2014)
The surface area of early visual cortex predicts the amplitude of the visual evoked potential
Brain Struct Funct, 220 (2), 1229-36
DOI 10.1007/s00429-013-0703-7, PubMed 24415060

Lövdahl H, Bøen E, Malt EA, Malt UF (2014)
Somatic and cognitive symptoms as indicators of potential endophenotypes in bipolar spectrum disorders: an exploratory and proof-of-concept study comparing bipolar II disorder with recurrent brief depression and healthy controls
J Affect Disord, 166, 59-70
DOI 10.1016/j.jad.2014.04.056, PubMed 25012411

Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME et al. (2014)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358

Publications 2013

Bøen E, Westlye LT, Elvsåshagen T, Hummelen B, Hol PK, Boye B, Andersson S, Karterud S, Malt UF (2013)
Regional cortical thinning may be a biological marker for borderline personality disorder
Acta Psychiatr Scand, 130 (3), 193-204
DOI 10.1111/acps.12234, PubMed 24571788

Elvsåshagen T, Westlye LT, Bøen E, Hol PK, Andersson S, Andreassen OA, Boye B, Malt UF (2013)
Evidence for reduced dentate gyrus and fimbria volume in bipolar II disorder
Bipolar Disord, 15 (2), 167-76
DOI 10.1111/bdi.12046, PubMed 23317454

Elvsåshagen T, Westlye LT, Bøen E, Hol PK, Andreassen OA, Boye B, Malt UF (2013)
Bipolar II disorder is associated with thinning of prefrontal and temporal cortices involved in affect regulation
Bipolar Disord, 15 (8), 855-64
DOI 10.1111/bdi.12117, PubMed 23980618

Publications 2011

Elvsåshagen T, Moberget T, Bøen E, Boye B, Englin NO, Pedersen PØ, Andreassen OA, Dietrichs E, Malt UF, Andersson S (2011)
Evidence for impaired neocortical synaptic plasticity in bipolar II disorder
Biol Psychiatry, 71 (1), 68-74
DOI 10.1016/j.biopsych.2011.09.026, PubMed 22036034

Elvsåshagen T, Vera E, Bøen E, Bratlie J, Andreassen OA, Josefsen D, Malt UF, Blasco MA, Boye B (2011)
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
J Affect Disord, 135 (1-3), 43-50
DOI 10.1016/j.jad.2011.08.006, PubMed 21880373

Publications 2010

Lövdahl H, Bøen E, Falkum E, Hynnekleiv T, Malt UF (2010)
Temperament and character in patients with bipolar II disorder and recurrent brief depression
Compr Psychiatry, 51 (6), 607-17
DOI 10.1016/j.comppsych.2010.03.003, PubMed 20965308