- T-B cell collaboration where T cells recognize immunoglobulin variable region peptides (Id-peptides) on MHC II molecules on B cells. The importance of BCR (B cell receptor ligation) and T cell help in such Id-driven T-B collaboration. The relationship of chronic Id-driven T-B collaboration to development of autoimmunity and B cell lymphomas.
- Studies on bystander killing effected by Id-specific CD4+ T cells. The mechanisms by which tumors can escape killing by CD4+ T cells.
- Development of DNA vaccines that as proteins target fused antigen to antigen presenting cells for induction of strong immune responses against influenza virus (The Vaccibody principle).
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine (in press)
Rettelse: Lungeembolisme ved covid-19
Tidsskr Nor Laegeforen, 140 (1)
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
Acta Biomater, 119, 247-258