- T-B cell collaboration where T cells recognize immunoglobulin variable region peptides (Id-peptides) on MHC II molecules on B cells. The importance of BCR (B cell receptor ligation) and T cell help in such Id-driven T-B collaboration. The relationship of chronic Id-driven T-B collaboration to development of autoimmunity and B cell lymphomas.
- Studies on bystander killing effected by Id-specific CD4+ T cells. The mechanisms by which tumors can escape killing by CD4+ T cells.
- Development of DNA vaccines that as proteins target fused antigen to antigen presenting cells for induction of strong immune responses against influenza virus (The Vaccibody principle).
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
Acta Biomater (in press)
Charge-altering releasable transporters enable phenotypic manipulation of natural killer cells for cancer immunotherapy
Blood Adv, 4 (17), 4244-4255
Komplikasjoner og dødelighet blant pasienter innlagt med covid-19
Tidsskr Nor Laegeforen, 140 (11)