Publications 2021

Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullen S, Rylander C, Wise MP, Oddo M, Cariou A, Belohlavek J, Hovdenes J, Saxena M, Kirkegaard H, Young PJ, Pelosi P, Storm C, Taccone FS, Joannidis M, Callaway C, Eastwood GM, Morgan MPG, Nordberg P, Erlinge D, Nichol AD et al. (2021)
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest
N. Engl. J. Med., 384 (24), 2283-2294
DOI 10.1056/NEJMoa2100591

Publications 2020

Jakobsen JC, Dankiewicz J, Lange T, Cronberg T, Lilja G, Levin H, Belohlavek J, Callaway C, Cariou A, Erlinge D, Hovdenes J, Joannidis M, Nordberg P, Oddo M, Pelosi P, Kirkegaard H, Eastwood G, Rylander C, Saxena M, Storm C, Taccone FS, Wise MP, Morgan MPG, Young P, Nichol A et al. (2020)
Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest: a statistical analysis plan
Trials, 21 (1), 831
DOI 10.1186/s13063-020-04654-y

Lilja G, Nielsen N, Ullen S, Nordstrom EB, Dankiewicz J, Friberg H, Heimburg K, Jakobsen JC, Levin H, Callaway C, Cariou A, Eastwood GM, Helbok R, Hovdenes J, Kirkegaard H, Leithner C, Morgan MPG, Nordberg P, Oddo M, Pelosi P, Rylander C, Saxena M, Taccone FS, Siranec M, Wise MP et al. (2020)
Protocol for outcome reporting and follow-up in the Targeted Hypothermia versus Targeted Normothermia after Out -of -Hospital Cardiac Arrest trial (TTM2)
Resuscitation, 150, 104-112

Publications 2019

Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Belohlavek J, Callaway C, Cariou A, Eastwood G, Erlinge D, Hovdenes J, Joannidis M, Kirkegaard H, Kuiper M, Levin H, Morgan MPG, Nichol AD, Nordberg P, Oddo M, Pelosi P, Rylander C, Saxena M, Storm C, Taccone F, Ullen S, Wise MP et al. (2019)
Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design
Am. Heart J., 217, 23-31
DOI 10.1016/j.ahj.2019.06.012

Totland C, Thomas PJ, Holst B, Akhtar N, Hovdenes J, Skodvin T (2019)
The use of surfactant-filled mesoporous silica as an immobilising medium for a fluorescence lifetime pH indicator, providing long-term calibration stability
RSC Adv., 9 (64), 37241-37244
DOI 10.1039/c9ra07374d

Publications 2018

During J, Dankiewicz J, Cronberg T, Hassager C, Hovdenes J, Kjaergaard J, Kuiper M, Nielsen N, Pellis T, Stammet P, Vulto J, Wanscher M, Wise M, Aneman A, Friberg H (2018)
Lactate, lactate clearance and outcome after cardiac arrest: A post-hoc analysis of the TTM-Trial
Acta Anaesthesiol. Scand., 62 (10), 1436-1442
DOI 10.1111/aas.13172

Lybeck A, Cronberg T, Aneman A, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M, Wanscher M, Stammet P, Wise MP, Nielsen N, Ullen S, Friberg H, TTM-Trial Investigators (2018)
Time to awakening after cardiac arrest and the association with target temperature management
Resuscitation, 126, 166-171
DOI 10.1016/j.resuscitation.2018.01.027

Publications 2017

Stammet P, Dankiewicz J, Nielsen N, Fays F, Collignon O, Hassager C, Wanscher M, Unden J, Wetterslev J, Pellis T, Aneman A, Hovdenes J, Wise MP, Gilson G, Erlinge D, Horn J, Cronberg T, Kuiper M, Kjaergaard J, Gasche Y, Devaux Y, Friberg H, Target Temperature Management (2017)
Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 degrees C and 36 degrees C
Crit. Care, 21, 153
DOI 10.1186/s13054-017-1729-7

Wiberg S, Hassager C, Stammet P, Winther-Jensen M, Thomsen JH, Erlinge D, Wanscher M, Nielsen N, Pellis T, Aneman A, Friberg H, Hovdenes J, Horn J, Wetterslev J, Bro-Jeppesen J, Wise MP, Kuiper M, Cronberg T, Gasche Y, Devaux Y, Kjaergaard J (2017)
Single versus Serial Measurements of Neuron-Specific Enolase and Prediction of Poor Neurological Outcome in Persistently Unconscious Patients after Out-Of-Hospital Cardiac Arrest - A TTM-Trial Substudy
PLoS One, 12 (1), e0168894
DOI 10.1371/journal.pone.0168894

Publications 2016

Bro-Jeppesen J, Kjaergaard J, Stammet P, Wise MP, Hovdenes J, Aneman A, Horn J, Devaux Y, Erlinge D, Gasche Y, Wanscher M, Cronberg T, Friberg H, Wetterslev J, Pellis T, Kuiper M, Nielsen N, Hassager C, TTM-Trial Investigators (2016)
Predictive value of interleukin-6 in post-cardiac arrest patients treated with targeted temperature management at 33 degrees C or 36 degrees C
Resuscitation, 98, 1-8
DOI 10.1016/j.resuscitation.2015.10.009

Dankiewicz J, Friberg H, Belohlavek J, Walden A, Hassager C, Cronberg T, Erlinge D, Gasche Y, Hovdenes J, Horn J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wetterslev J, Wise M, Aneman A, Nielsen N (2016)
Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33 degrees C and 36 degrees C
Resuscitation, 99, 44-49
DOI 10.1016/j.resuscitation.2015.10.013

Frydland M, Kjaergaard J, Erlinge D, Stammet P, Nielsen N, Wanscher M, Pellis T, Friberg H, Hovdenes J, Horn J, Wetterslev J, Thomsen JH, Bro-Jeppesen J, Winther-Jensen M, Wise MP, Kuiper M, Cronberg T, Gasche Y, Devaux Y, Aneman A, Hassager C (2016)
Usefulness of Serum B-Type Natriuretic Peptide Levels in Comatose Patients Resuscitated from Out-of-Hospital Cardiac Arrest to Predict Outcome
Am. J. Cardiol., 118 (7), 998-1005
DOI 10.1016/j.amjcard.2016.07.006

Hovdenes J, Roysland K, Nielsen N, Kjaergaard J, Wanscher M, Hassager C, Wetterslev J, Cronberg T, Erlinge D, Friberg H, Gasche Y, Horn J, Kuiper M, Pellis T, Stammet P, Wise MP, Aneman A, Bugge JF (2016)
A low body temperature on arrival at hospital following out-of-hospital-cardiac-arrest is associated with increased mortality in the TTM-study
Resuscitation, 107, 102-106
DOI 10.1016/j.resuscitation.2016.08.011

Thomsen JH, Hassager C, Erlinge D, Nielsen N, Horn J, Hovdenes J, Bro-Jeppesen J, Wanscher M, Pehrson S, Kober L, Kjaergaard J (2016)
Atrial Fibrillation Following Out-of-Hospital Cardiac Arrest and Targeted Temperature Management-Are We Giving It the Attention it Deserves?
Crit. Care Med., 44 (12), 2215-2222
DOI 10.1097/CCM.0000000000001958

Westhall E, Rossetti AO, van Rootselaar AF, Kjaer TW, Horn J, Ullen S, Friberg H, Nielsen N, Rosen I, Aneman A, Erlinge D, Gasche Y, Hassager C, Hovdenes J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wetterslev J, Wise MP, Cronberg T, TTM-trial Investigators (2016)
Standardized EEG interpretation accurately predicts prognosis after cardiac arrest
Neurology, 86 (16), 1482-1490
DOI 10.1212/WNL.0000000000002462

Publications 2015

Cronberg T, Lilja G, Horn J, Kjaergaard J, Wise MP, Pellis T, Hovdenes J, Gasche Y, Aneman A, Stammet P, Erlinge D, Friberg H, Hassager C, Kuiper M, Wanscher M, Bosch F, Cranshaw J, Kleger GR, Persson S, Unden J, Walden A, Winkel P, Wetterslev J, Nielsen N, TTM Trial Investigators (2015)
Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33 degrees C vs 36 degrees C After Out-of-Hospital Cardiac Arrest A Randomized Clinical Trial
JAMA Neurol., 72 (6), 634-641
DOI 10.1001/jamaneurol.2015.0169

Frydlandad M, Kjaergaard J, Erlinge D, Wanscher M, Nielsen N, Pellis T, Aneman A, Friberg H, Hovdenes J, Horn J, Wetterslev J, Winther-Jensen M, Wise MP, Kuiper M, Stammet P, Cronberg T, Gasche Y, Hassager C (2015)
Target temperature management of 33 degrees C and 36 degrees C in patients with out-of-hospital cardiac arrest with initial non-shockable rhythm - A TTM sub-study
Resuscitation, 89, 142-148
DOI 10.1016/j.resuscitation.2014.12.033

Gagnon DJ, Nielsen N, Fraser GL, Riker RR, Dziodzio J, Sunde K, Hovdenes J, Stammet P, Friberg H, Rubertsson S, Wanscher M, Seder DB (2015)
Prophylactic antibiotics are associated with a lower incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management
Resuscitation, 92, 154-159
DOI 10.1016/j.resuscitation.2015.01.035

Kjaergaard J, Nielsen N, Winther-Jensen M, Wanscher M, Pellis T, Kuiper M, Thomsen JH, Wetterslev J, Cronberg T, Bro-Jeppesen J, Erlinge D, Friberg H, Soholm H, Gasche Y, Horn J, Hovdenes J, Stammet P, Wise MP, Aneman A, Hassager C (2015)
Impact of time to return of spontaneous circulation on neuroprotective effect of targeted temperature management at 33 or 36 degrees in comatose survivors of out-of hospital cardiac arrest
Resuscitation, 96, 310-316
DOI 10.1016/j.resuscitation.2015.06.021

Stammet P, Collignon O, Hassager C, Wise MP, Hovdenes J, Aneman A, Horn J, Devaux Y, Erlinge D, Kjaergaard J, Gasche Y, Wanscher M, Cronberg T, Friberg H, Wetterslev J, Pellis T, Kuiper M, Gilson G, Nielsen N, TTM-Trial Investigators (2015)
Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33 degrees C and 36 degrees C
J. Am. Coll. Cardiol., 65 (19), 2104-2114
DOI 10.1016/j.jacc.2015.03.538

Winther-Jensen M, Kjaergaard J, Wanscher M, Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Friberg H, Gasche Y, Horn J, Hovdenes J, Kuiper M, Pellis T, Stammet P, Wise MP, Aneman A, Hassager C (2015)
No difference in mortality between men and women after out-of-hospital cardiac arrest
Resuscitation, 96, 78-84
DOI 10.1016/j.resuscitation.2015.06.030

Winther-Jensen M, Pellis T, Kuiper M, Koopmans M, Hassager C, Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Friberg H, Gasche Y, Horn J, Hovdenes J, Stammet P, Wanscher M, Wise MP, Aneman A, Kjaergaard J (2015)
Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest
Resuscitation, 91, 92-98
DOI 10.1016/j.resuscitation.2014.12.030

Publications 2014

Annborn M, Bro-Jeppesen J, Nielsen N, Ullen S, Kjaergaard J, Hassager C, Wanscher M, Hovdenes J, Pellis T, Pelosi P, Wise MP, Cronberg T, Erlinge D, Friberg H, TTM Trial Investigators (2014)
The association of targeted temperature management at 33 and 36 A degrees C with outcome in patients with moderate shock on admission after out-of-hospital cardiac arrest: a post hoc analysis of the Target Temperature Management trial
Intensive Care Med., 40 (9), 1210-1219
DOI 10.1007/s00134-014-3375-8

Publications 2013

Nielsen N, Wettersley J, Cronberg T, Erlinge D, Gasche Y, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wise MP, Aneman A, Al-Subaie N, Boesgaard S, Bro-Jeppesen J, Brunetti I, Bugge JF, Hingston CD, Juffermans NP, Koopmans M, Kober L, Langorgen J et al. (2013)
Targeted Temperature Management at 33 degrees C versus 36 degrees C after Cardiac Arrest
N. Engl. J. Med., 369 (23), 2197-2206
DOI 10.1056/NEJMoa1310519

Nielsen N, Winkel P, Cronberg T, Erlinge D, Friberg H, Gasche Y, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wise MP, Aneman A, Wetterslev J (2013)
Detailed statistical analysis plan for the target temperature management after out-of-hospital cardiac arrest trial
Trials, 14, 300
DOI 10.1186/1745-6215-14-300

Thomas PJ, Pedersen G, Hovdenes J, Tengberg A, Hide A, Hall POJ, Atamanchuk D, Apostolidis A, Huber C, Putnam R, Putnam J (2013)
Optical gas monitoring in sea water: Robust reliable and highly flexible
OCEANS-IEEE

Publications 2012

Nielsen N, Wetterslev J, al-Subaie N, Andersson B, Bro-Jeppesen J, Bishop G, Brunetti I, Cranshaw J, Cronberg T, Edqvist K, Erlinge D, Gasche Y, Glover G, Hassager C, Horn J, Hovdenes J, Johnsson J, Kjaergaard J, Kuiper M, Langorgen J, Macken L, Martinell L, Martner P, Pellis T, Pelosi P et al. (2012)
Target temperature management after out-of-hospital cardiac arrest-a randomized, parallel-group, assessor-blinded clinical trial-rationale and design
Am. Heart J., 163 (4), 541-548
DOI 10.1016/j.ahj.2012.01.013

Publications 2011

Espinoza A, Rosseland LA, Hovdenes J, Stubhaug A (2011)
Paratracheal placement of orotracheal tube: a complication when aborting percutaneous tracheotomy
Acta Anaesthesiol. Scand., 55 (7), 897-898
DOI 10.1111/j.1399-6576.2011.02438.x

Nielsen N, Sunde K, Hovdenes J, Riker RR, Rubertsson S, Stammet P, Nilsson F, Friberg H, Hypothermia Network (2011)
Adverse events and their relation to mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia
Crit. Care Med., 39 (1), 57-64
DOI 10.1097/CCM.0b013e3181fa4301

Publications 2009

Nielsen N, Hovdenes J, Nilsson F, Rubertsson S, Stammet P, Sunde K, Valsson F, Wanscher M, Friberg H, Hypothermia Network (2009)
Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest
Acta Anaesthesiol. Scand., 53 (7), 926-934
DOI 10.1111/j.1399-6576.2009.02021.x

Publications 2007

Hovdenes J, Laake JH, Haugaa H, Aaberge L, Bugge JF (2007)
Reply to Systemic vascular resistance with an intra-aortic balloon pump: of practical use, even for a petit-maitre?
Acta Anaesthesiol. Scand., 51 (7)
DOI 10.1111/j.1399-6576.2007.01345.x

Hovdenes J, Laake JH, Aaberge L, Haugaa H, Bugge JF (2007)
Therapeutic hypothermia after out-of-hospital cardiac arrest: experiences with patients treated with percutaneous coronary intervention and cardiogenic shock
Acta Anaesthesiol. Scand., 51 (2), 137-142
DOI 10.1111/j.1399-6576.2006.01209.x

Publications 2006

Tengberg A, Hovdenes J, Andersson HJ, Brocandel O, Diaz R, Hebert D, Arnerich T, Huber C, Kortzinger A, Khripounoff A, Rey F, Ronning C, Schimanski J, Sommer S, Stangelmayer A (2006)
Evaluation of a lifetime-based optode to measure oxygen in aquatic systems
Limnol. Oceanogr. Meth., 4, 7-17
DOI 10.4319/lom.2006.4.7

Publications 2003

Tengberg A, Hovdenes J, Barranger D, Brocandel O, Diaz R, Sarkkula J, Huber C, Stangelmayer A (2003)
Optodes to measure oxygen in the aquatic environment
Sea Technol., 44 (2), 10-15

Publications 2001

Tengberg A, Pejrup M, Andersen TJ, Guillen J, Palanques A, Hovdenes J, Minken H, Ingvaldsen R, Loeng H, Jozsa J, Sarkkula J (2001)
Use of current meters in aquatic research & engineering
Sea Technol., 42 (2), 10-18

Publications 1996

Hovdenes J (1996)
The RCM 9 - A unique new instrument for measuring ocean currents and other oceanographic parameters
OCEANS '96 MTS/IEEE, CONFERENCE PROCEEDINGS, VOLS 1-3 / SUPPLEMENTARY PROCEEDINGS: COASTAL OCEAN - PROSPECTS FOR THE 21ST CENTURY, 293-298

Publications 1995

HOGASEN K, JANSEN JH, MOLLNES TE, HOVDENES J, HARBOE M (1995)
HEREDITARY PORCINE MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS TYPE-II IS CAUSED BY FACTOR-H DEFICIENCY
J. Clin. Invest., 95 (3), 1054-1061
DOI 10.1172/JCI117751

Publications 1990

HOVDENES J, HOVDENES AB, EGELAND T, KVIEN TK, MELLBYE OJ (1990)
A STUDY OF THE EFFECT OF RHEUMATOID SYNOVIAL-FLUID ON PROLIFERATION AND IL-2 PRODUCTION BY TOTAL MONONUCLEAR-CELLS AND PURIFIED CD4+ CELLS OF SYNOVIAL-FLUID AND PERIPHERAL-BLOOD
Scand. J. Rheumatol., 19 (6), 398-406
DOI 10.3109/03009749009097628

HOVDENES J, KVIEN TK, HOVDENES AB (1990)
IL-6 IN SYNOVIAL-FLUIDS, PLASMA AND SUPERNATANTS FROM CULTURED-CELLS OF PATIENTS WITH RHEUMATOID-ARTHRITIS AND OTHER INFLAMMATORY ARTHRITIDES
Scand. J. Rheumatol., 19 (3), 177-182
DOI 10.3109/03009749009095040

Publications 1989

HOVDENES J (1989)
B-CELL GROWTH-PROMOTING ACTIVITY IN SUPERNATANTS FROM CD4+ CELLS FROM SYNOVIAL-FLUID AND PERIPHERAL-BLOOD OF PATIENTS WITH RHEUMATOID-ARTHRITIS AND OTHER INFLAMMATORY ARTHRITIDES
Scand. J. Rheumatol., 18 (6), 385-392
DOI 10.3109/03009748909102100

HOVDENES J, GAUDERNACK G, KVIEN TK, EGELAND T (1989)
EXPRESSION OF ACTIVATION MARKERS ON CD4+ AND CD8+ CELLS FROM SYNOVIAL-FLUID, SYNOVIAL TISSUE, AND PERIPHERAL-BLOOD OF PATIENTS WITH INFLAMMATORY ARTHRITIDES
Scand. J. Immunol., 29 (6), 631-639
DOI 10.1111/j.1365-3083.1989.tb01167.x

HOVDENES J, GAUDERNACK G, KVIEN TK, EGELAND T, MELLBYE OJ (1989)
A FUNCTIONAL-STUDY OF PURIFIED CD4+ AND CD8+ CELLS ISOLATED FROM SYNOVIAL-FLUID OF PATIENTS WITH RHEUMATOID-ARTHRITIS AND OTHER ARTHRITIDES
Scand. J. Immunol., 29 (6), 641-649
DOI 10.1111/j.1365-3083.1989.tb01168.x

HOVDENES J, GAUDERNACK G, KVIEN TK, HOVDENES AB, EGELAND T (1989)
MITOGEN-INDUCED INTERLEUKIN-2 AND GAMMA-INTERFERON PRODUCTION BY CD4+ AND CD8+ CELLS OF PATIENTS WITH INFLAMMATORY ARTHRITIDES - A COMPARISON BETWEEN CELLS FROM SYNOVIAL-FLUID AND PERIPHERAL-BLOOD
Scand. J. Immunol., 30 (5), 597-603
DOI 10.1111/j.1365-3083.1989.tb02467.x

Publications 1988

HOVDENES J, LUND H, LEA T, EGELAND T (1988)
IMMUNOREGULATORY LYMPHOKINES IN RHEUMATOID JOINTS .3. B-CELL GROWTH-PROMOTING ACTIVITY OF CELLS ELUTED FROM RHEUMATOID SYNOVIAL TISSUE
Scand. J. Rheumatol., 17 (5), 371-378
DOI 10.3109/03009748809105273

Publications 1987

HOVDENES J, EGELAND T (1987)
IMMUNOREGULATORY LYMPHOKINES IN RHEUMATOID JOINTS .2. PRODUCTION BY AND RESPONSIVENESS TO INTERLEUKIN-2 OF ELUTED SYNOVIAL TISSUE-CELLS
Rheumatol. Int., 7 (6), 261-265
DOI 10.1007/BF00270526