Publications 2022

Laake JH, Astvad M, Bentsen G, Escher C, Haney M, Hoffmann-Petersen J, Hyllested M, Junttila E, Moller MH, Nellgard P, Nyberg A, Olkkola K, Pedersen SKA, Pischke SE, Reinikainen M, Strand K, Thorarensen G, Thormar K, Tonnessen TI (2022)
A policy for diversity, equity, inclusion and anti-racism in the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI)
Acta Anaesthesiol. Scand., 66 (1), 141-144
DOI 10.1111/aas.13978

Publications 2021

Chaban V, Nakstad ER, Staer-Jensen H, Schjalm C, Seljeflot I, Vaage J, Lundqvist C, Benth JA, Sunde K, Mollnes TE, Andersen GO, Pischke SE (2021)
Complement activation is associated with poor outcome after out-of-hospital cardiac arrest
Resuscitation, 166, 129-136
DOI 10.1016/j.resuscitation.2021.05.038

Kjosen G, Rydenfelt K, Horneland R, Aandahl EM, Line PD, Dorenberg E, Berstad AE, Brabrand K, Hagen G, Pischke SE, Bergmann GB, Nordheim E, Jenssen TG, Tonnessen TI, Haugaa H (2021)
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
PLoS One, 16 (3), e0247615
DOI 10.1371/journal.pone.0247615

Rognes IN, Pischke SE, Ottestad W, Roislien J, Berg JP, Johnson C, Eken T, Mollnes TE (2021)
Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study
Mol. Med., 27 (1), 35
DOI 10.1186/s10020-021-00286-3

Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jorgensen MJ, Barratt-Due A, Skeie LG, Nordoy I, Fraz MSA, Quist-Paulsen E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Muller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2021)
Elevated plasma sTIM-3 levels in patients with severe COVID-19
J. Allergy Clin. Immunol., 147 (1), 92-98
DOI 10.1016/j.jaci.2020.09.007

Witczak BJ, Pischke SE, Reisaeter AV, Midtvedt K, Ludviksen JK, Heldal K, Jenssen T, Hartmann A, Asberg A, Mollnes TE (2021)
Elevated Terminal C5b-9 Complement Complex 10 Weeks Post Kidney Transplantation Was Associated With Reduced Long-Term Patient and Kidney Graft Survival
Front. Immunol., 12, 738927
DOI 10.3389/fimmu.2021.738927

Publications 2020

Jorgensen MJ, Holter JC, Christensen EE, Schjalm C, Tonby K, Pischke SE, Jenum S, Skeie LG, Nur S, Lind A, Opsand H, Enersen TB, Grondahl R, Hermann A, Dudman S, Muller F, Ueland T, Mollnes TE, Aukrust P, Heggelund L, Holten AR, Dyrhol-Riise AM (2020)
Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
Sci Rep, 10 (1), 21697
DOI 10.1038/s41598-020-78710-7

Nieuwenhuijs-Moeke GJ, Pischke SE, Berger SP, Sanders JSF, Pol RA, Struys MMRF, Ploeg RJ, Leuvenink HGD (2020)
Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair
J. Clin. Med., 9 (1), 253
DOI 10.3390/jcm9010253

Publications 2019

Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE (2019)
The Role of Complement in Liver Injury, Regeneration, and Transplantation
Hepatology, 70 (2), 725-736
DOI 10.1002/hep.30508

Publications 2018

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GO, Barratt-Due A, Mollnes TE (2018)
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail., 5 (3), 292-301
DOI 10.1002/ehf2.12266

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damas JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GO, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front. Immunol., 9, 2035
DOI 10.3389/fimmu.2018.02035

Publications 2017

Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE (2017)
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
J. Leukoc. Biol., 101 (1), 193-204
DOI 10.1189/jlb.3VMR0316-132R

Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzaeg P, Nielsen EW, Mollnes TE (2017)
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
J. Intensive Care, 5, 21
DOI 10.1186/s40560-017-0217-0

Pischke SE, Haugaa H, Haney M (2017)
A neglected organ in multiple organ failure - 'skin in the game'?
Acta Anaesthesiol. Scand., 61 (1), 5-7
DOI 10.1111/aas.12823

Publications 2016

Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE (2016)
Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex
J. Infect. Dis., 214 (1), 140-150
DOI 10.1093/infdis/jiw100

Publications 2015

Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE (2015)
Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14
Immunobiology, 220 (8), 999-1005
DOI 10.1016/j.imbio.2015.04.002

Fretland AA, Sokolov A, Postriganova N, Kazaryan AM, Pischke SE, Nilsson PH, Rognes IN, Bjornbeth BA, Fagerland MW, Mollnes TE, Edwin B (2015)
Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases Data From the Oslo-CoMet Trial
Medicine (Baltimore), 94 (42), e1786
DOI 10.1097/MD.0000000000001786

Hyler S, Pischke SE, Halvorsen PS, Espinoza A, Bergsland J, Tonnessen TI, Fosse E, Skulstad H (2015)
Continuous Monitoring of Regional Function by a Miniaturized Ultrasound Transducer Allows Early Quantification of Low-Grade Myocardial Ischemia
J. Am. Soc. Echocardiogr., 28 (4), 486-494
DOI 10.1016/j.echo.2014.12.014

Khan F, Pharo A, Lindstad JK, Mollnes TE, Tonnessen TI, Pischke SE (2015)
Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis
Scand. J. Immunol., 82 (5), 467-475
DOI 10.1111/sji.12332

Pischke SE, Hyler S, Tronstad C, Bergsland J, Fosse E, Halvorsen PS, Skulstad H, Tonnessen TI (2015)
Myocardial tissue CO2 tension detects coronary blood flow reduction after coronary artery bypass in real-time
Br. J. Anaesth., 114 (3), 414-422
DOI 10.1093/bja/aeu381

Publications 2014

Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger O, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE (2014)
Double Blockade of CD14 and Complement C5 Abolishes the Cytokine Storm and Improves Morbidity and Survival in Polymicrobial Sepsis in Mice
J. Immunol., 192 (11), 5324-5331
DOI 10.4049/jimmunol.1400341

Publications 2013

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE (2013)
Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis
J. Immunol., 191 (2), 819-827
DOI 10.4049/jimmunol.1201909

Thorgersen EB, Pischke SE, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Hellerud BC, Mollnes TE (2013)
Systemic CD14 Inhibition Attenuates Organ Inflammation in Porcine Escherichia coli Sepsis
Infect. Immun., 81 (9), 3173-3181
DOI 10.1128/IAI.00390-13

Publications 2012

Pischke SE, Tronstad C, Holhjem L, Halvorsen PS, Tonnessen TI (2012)
Perioperative detection of myocardial ischaemia/reperfusion with a novel tissue CO2 monitoring technology
Eur. J. Cardio-Thorac. Surg., 42 (1), 157-163
DOI 10.1093/ejcts/ezr278