Anaesthesia & Intensive Care Research Group Publications

Antonsen LP, Espinoza A, Halvorsen PS, Schalit I, Bergan H, Lilja D, Landsverk SA (2024)
The impact of hypovolemia and PEEP on recirculation in venovenous ECMO: an experimental porcine model
Intensive Care Med Exp, 12 (1), 51
DOI 10.1186/s40635-024-00636-5, PubMed 38822111

Karlsen H, Strand-Amundsen RJ, Skåre C, Eriksen M, Skulberg VM, Sunde K, Tønnessen TI, Olasveengen TM (2024)
Cerebral perfusion and metabolism with mild hypercapnia vs. normocapnia in a porcine post cardiac arrest model with and without targeted temperature management
Resusc Plus, 18, 100604
DOI 10.1016/j.resplu.2024.100604, PubMed 38510376

Lie SL, Hisdal J, Rehn M, Høiseth LØ (2024)
Effect of systemic vascular resistance on the agreement between stroke volume by non-invasive pulse wave analysis and Doppler ultrasound in healthy volunteers
PLoS One, 19 (5), e0302159
DOI 10.1371/journal.pone.0302159, PubMed 38713665

Sjøen GH, Falk RS, Hauge TH, Tønnessen TI, Langesæter E (2024)
Haemodynamic effects of remifentanil during induction of general anaesthesia with propofol. A randomised trial
Acta Anaesthesiol Scand, 68 (5), 601-609
DOI 10.1111/aas.14394, PubMed 38400761

Høiseth LØ, Fjose LO, Hisdal J, Comelon M, Rosseland LA, Lenz H (2023)
Haemodynamic effects of methoxyflurane versus fentanyl and placebo in hypovolaemia: a randomised, double-blind crossover study in healthy volunteers
BJA Open, 7, 100204
DOI 10.1016/j.bjao.2023.100204, PubMed 37638077

Lie SL, Hisdal J, Rehn M, Høiseth LØ (2023)
Hemodynamic effects of supplemental oxygen versus air in simulated blood loss in healthy volunteers: a randomized, controlled, double-blind, crossover trial
Intensive Care Med Exp, 11 (1), 76
DOI 10.1186/s40635-023-00561-z, PubMed 37947905

Lilja D, Schalit I, Espinoza A, Fiane AE, Dahle G, Littorin-Sandbu H, Pettersen FJ, Russell KE, Thiara APS, Elle OJ, Halvorsen PS (2023)
Detection of inflow obstruction in left ventricular assist devices by accelerometer: A porcine model study
J Heart Lung Transplant, 42 (8), 1005-1014
DOI 10.1016/j.healun.2023.03.017, PubMed 37023840

Lilja D, Schalit I, Espinoza A, Hoel TN, Larsen G, Pettersen FJ, Halvorsen PS (2023)
Extracorporeal driveline vibrations to detect left ventricular assist device thrombosis - A porcine model study
J Heart Lung Transplant, 43 (1), 111-119
DOI 10.1016/j.healun.2023.08.022, PubMed 37673384

Laake JH, Aslam TN, Barratt-Due A, Løwhagen B, Pischke SE, Tønnessen TI, Wisløff-Aase K, Aasmundstad TA (2023)
[ARDS or acute respiratory failure syndrome?]
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.23.0402, PubMed 37376931

Rydenfelt K, Kjøsen G, Horneland R, Krey Ludviksen J, Jenssen TG, Line PD, Tønnessen TI, Mollnes TE, Haugaa H, Pischke SE (2023)
Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis
Transplant Direct, 10 (1), e1567
DOI 10.1097/TXD.0000000000001567, PubMed 38094132

Rydenfelt K, Kjøsen G, Horneland R, Ludviksen JK, Jenssen TG, Line PD, Tønnessen TI, Mollnes TE, Haugaa H, Pischke SE (2023)
Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation
Front Immunol, 14, 1044444
DOI 10.3389/fimmu.2023.1044444, PubMed 37063904

Sjøen GH, Falk RS, Hauge TH, Tønnessen TI, Langesaeter E (2023)
Hemodynamic effects of a low versus a high dose of propofol during induction of anesthesia. A randomized trial
Acta Anaesthesiol Scand, 67 (9), 1178-1186
DOI 10.1111/aas.14293, PubMed 37291731

Djupedal H, Nøstdahl T, Hisdal J, Landsverk SA, Høiseth LØ (2022)
Effects of experimental hypovolemia and pain on pre-ejection period and pulse transit time in healthy volunteers
Physiol Rep, 10 (12), e15355
DOI 10.14814/phy2.15355, PubMed 35748055

Hou J, Liavåg OMI, Færden IH, Martinsen ØG, Tønnessen TI, Line PD, Hagness M, Høgetveit JO, Pischke SE, Strand-Amundsen R (2022)
Utilization of dielectric properties for assessment of liver ischemia-reperfusion injury in vivo and during machine perfusion
Sci Rep, 12 (1), 11183
DOI 10.1038/s41598-022-14817-3, PubMed 35778457

Hou J, Ness SS, Tschudi J, O'Farrell M, Veddegjerde R, Martinsen ØG, Tønnessen TI, Strand-Amundsen R (2022)
Assessment of Intestinal Ischemia-Reperfusion Injury Using Diffuse Reflectance VIS-NIR Spectroscopy and Histology
Sensors (Basel), 22 (23)
DOI 10.3390/s22239111, PubMed 36501812

Hou J, Strand-Amundsen R, Tronstad C, Tønnessen TI, Høgetveit JO, Martinsen ØG (2022)
Small intestinal viability assessment using dielectric relaxation spectroscopy and deep learning
Sci Rep, 12 (1), 3279
DOI 10.1038/s41598-022-07140-4, PubMed 35228559

Kjøsen G, Horneland R, Nordheim E, Aandahl EM, Line PD, Rydenfelt K, Jenssen TG, Tønnessen TI, Haugaa H (2022)
Validating the US pancreas donor risk index in a Norwegian population, a retrospective observational study
Scand J Gastroenterol, 57 (3), 345-351
DOI 10.1080/00365521.2021.2012590, PubMed 35130456

Lilja D, Schalit I, Espinoza A, Pettersen FJ, Elle OJ, Halvorsen PS (2022)
Detection of inflow obstruction in left ventricular assist devices by accelerometer: An in vitro study
Med Eng Phys, 110, 103917
DOI 10.1016/j.medengphy.2022.103917, PubMed 36564132

Lindvåg Lie S, Hisdal J, Rehn M, Høiseth LØ (2022)
Effects of supplemental oxygen on systemic and cerebral hemodynamics in experimental hypovolemia: Protocol for a randomized, double blinded crossover study
PLoS One, 17 (6), e0270598
DOI 10.1371/journal.pone.0270598, PubMed 35749486

Rydenfelt K, Strand-Amundsen R, Horneland R, Hødnebø S, Kjøsen G, Pischke SE, Tønnessen TI, Haugaa H (2022)
Microdialysis and CO2 sensors detect pancreatic ischemia in a porcine model
PLoS One, 17 (2), e0262848
DOI 10.1371/journal.pone.0262848, PubMed 35143517

Schalit I, Espinoza A, Pettersen FJ, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2022)
Improved Detection Of Thromboembolic Complications In Left Ventricular Assist Device By Novel Accelerometer-Based Analysis
ASAIO J, 68 (9), 1117-1125
DOI 10.1097/MAT.0000000000001654, PubMed 36066353

Wisløff-Aase K, Skulstad H, Beitnes JO, Lundblad R, Halvorsen PS, Fiane A, Espinoza A (2022)
Left Ventricular Function Changes Induced by Moderate Hypothermia Are Rapidly Reversed After Rewarming-A Clinical Study
Crit Care Med, 50 (1), e52-e60
DOI 10.1097/CCM.0000000000005170, PubMed 34259452

Wisløff-Aase K, Skulstad H, Haugaa K, Lingaas PS, Beitnes JO, Halvorsen PS, Espinoza A (2022)
Myocardial electrophysiological and mechanical changes caused by moderate hypothermia-A clinical study
Physiol Rep, 10 (8), e15259
DOI 10.14814/phy2.15259, PubMed 35439365

Hausken J, Haugaa H, Hagness M, Line PD, Melum E, Tønnessen TI (2021)
Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients
Transplant Direct, 7 (2), e648
DOI 10.1097/TXD.0000000000001101, PubMed 33437863

Hoel H, Pettersen EM, Høiseth LØ, Mathiesen I, Seternes A, Hisdal J (2021)
Lower Extremity Intermittent Negative Pressure for Intermittent Claudication. Follow-Up after 24 Weeks of Treatment
Ann Vasc Surg, 75, 253-258
DOI 10.1016/j.avsg.2021.03.016, PubMed 33823265

Hoel H, Pettersen EM, Høiseth LØ, Mathiesen I, Seternes A, Seljeflot I, Hisdal J (2021)
Effects of intermittent negative pressure treatment on circulating vascular biomarkers in patients with intermittent claudication
Vasc Med, 26 (5), 489-496
DOI 10.1177/1358863X211007933, PubMed 33985385

Hou J, Strand-Amundsen R, Hødnebø S, Tønnessen TI, Høgetveit JO (2021)
Assessing Ischemic Injury in Human Intestine Ex Vivo with Electrical Impedance Spectroscopy
J Electr Bioimpedance, 12 (1), 82-88
DOI 10.2478/joeb-2021-0011, PubMed 34966469

Hou J, Strand-Amundsen R, Tronstad C, Høgetveit JO, Martinsen ØG, Tønnessen TI (2021)
Automatic Prediction of Ischemia-Reperfusion Injury of Small Intestine Using Convolutional Neural Networks: A Pilot Study
Sensors (Basel), 21 (19)
DOI 10.3390/s21196691, PubMed 34641009

Høiseth LØ, Melau J, Bonnevie-Svendsen M, Nyborg C, Eijsvogels TMH, Hisdal J (2021)
Core Temperature during Cold-Water Triathlon Swimming
Sports (Basel), 9 (6)
DOI 10.3390/sports9060087, PubMed 34203083

Kjønås D, Dahle G, Schirmer H, Malm S, Eidet J, Aaberge L, Steigen T, Aakhus S, Busund R, Rösner A (2021)
Risk scores for prediction of 30-day mortality after transcatheter aortic valve implantation: Results from a two-center study in Norway
Health Sci Rep, 4 (2), e283
DOI 10.1002/hsr2.283, PubMed 33977165

Kjønås D, Schirmer H, Aakhus S, Eidet J, Malm S, Aaberge L, Busund R, Rösner A (2021)
Clinical and Echocardiographic Parameters Predicting 1- and 2-Year Mortality After Transcatheter Aortic Valve Implantation
Front Cardiovasc Med, 8, 739710
DOI 10.3389/fcvm.2021.739710, PubMed 34938779

Kjøsen G, Rydenfelt K, Horneland R, Aandahl EM, Line PD, Dorenberg E, Berstad AE, Brabrand K, Hagen G, Pischke SE, Bergmann GB, Nordheim E, Jenssen TG, Tønnessen TI, Haugaa H (2021)
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study
PLoS One, 16 (3), e0247615
DOI 10.1371/journal.pone.0247615, PubMed 33705460

Lenz H, Høiseth LØ, Comelon M, Draegni T, Rosseland LA (2021)
Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study
Br J Anaesth, 126 (5), 1038-1045
DOI 10.1016/j.bja.2020.12.045, PubMed 33676727

Lie SL, Hisdal J, Høiseth LØ (2021)
Cerebral blood flow velocity during simultaneous changes in mean arterial pressure and cardiac output in healthy volunteers
Eur J Appl Physiol, 121 (8), 2207-2217
DOI 10.1007/s00421-021-04693-6, PubMed 33890157

Lindholm E, Bergmann GB, Haugaa H, Labori KJ, Yaqub S, Bjørnbeth BA, Line PD, Grindheim G, Kjøsen G, Pischke SE, Tønnessen TI (2021)
Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study
HPB (Oxford), 24 (6), 901-909
DOI 10.1016/j.hpb.2021.10.020, PubMed 34836755

Lindholm E, Ekiz N, Tønnessen TI (2021)
Monitoring of patients with microdialysis following pancreaticoduodenectomy-the MINIMUM study: study protocol for a randomized controlled trial
Trials, 22 (1), 329
DOI 10.1186/s13063-021-05221-9, PubMed 33962656

Laake JH, Astvad M, Bentsen G, Escher C, Haney M, Hoffmann-Petersen J, Hyllested M, Junttila E, Møller MH, Nellgård P, Nyberg A, Olkkola K, Pedersen SKA, Pischke SE, Reinikainen M, Strand K, Thorarensen G, Thormar K, Tønnessen TI (2021)
A policy for diversity, equity, inclusion and anti-racism in the Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI)
Acta Anaesthesiol Scand, 66 (1), 141-144
DOI 10.1111/aas.13978, PubMed 34462910

Pradhan GN, Ottestad W, Meland A, Kåsin JI, Høiseth LØ, Cevette MJ, Stepanek J (2021)
Oculometric Feature Changes During Acute Hypoxia in a Simulated High-Altitude Airdrop Scenario
Aerosp Med Hum Perform, 92 (12), 928-936
DOI 10.3357/AMHP.5930.2021, PubMed 34986930

Skåre C, Karlsen H, Strand-Amundsen RJ, Eriksen M, Skulberg VM, Sunde K, Tønnessen TI, Olasveengen TM (2021)
Cerebral perfusion and metabolism with mean arterial pressure 90 vs. 60 mmHg in a porcine post cardiac arrest model with and without targeted temperature management
Resuscitation, 167, 251-260
DOI 10.1016/j.resuscitation.2021.06.011, PubMed 34166747

Strand-Amundsen R, Tronstad C, Elvebakk O, Martinsen T, Dybwad M, Lingaas E, Tønnessen TI (2021)
Quantification of aerosol dispersal from suspected aerosol-generating procedures
ERJ Open Res, 7 (4)
DOI 10.1183/23120541.00206-2021, PubMed 34877350

Sun X, Zhu S, Dong X, Strand-Amundsen RJ, Tonnessen TI, Yang R (2021)
Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis
Biomed Pharmacother, 137, 111392
DOI 10.1016/j.biopha.2021.111392, PubMed 33761609

Espinoza A, Kerans V, Bugge JF, Skulstad H, Halvorsen PS (2020)
Left Ventricular Function During Epinephrine Stimulation and Hypothermia: Effects at Spontaneous and Paced Heart Rates in a Porcine Model
Ther Hypothermia Temp Manag, 11 (1), 35-44
DOI 10.1089/ther.2019.0035, PubMed 31916922

Haugaa H, Line PD, Tønnessen TI (2020)
An Increased Lactate-to-pyruvate Ratio Is Not a Stand-alone Marker of Ischemia
Transplant Direct, 6 (5), e551
DOI 10.1097/TXD.0000000000000991, PubMed 32548245

Hausken J, Fretland ÅA, Edwin B, Kvarstein G, Tønnessen TI (2020)
Response to the Comment on "Epidural Analgesia (TEA) vs. IV-PCA After Open Liver Surgery"
Ann Surg, 271 (5), e126-e127
DOI 10.1097/SLA.0000000000003684, PubMed 31800498

Hoel H, Pettersen EM, Høiseth LØ, Mathiesen I, Seternes A, Hisdal J (2020)
A randomized controlled trial of treatment with intermittent negative pressure for intermittent claudication
J Vasc Surg, 73 (5), 1750-1758.e1
DOI 10.1016/j.jvs.2020.10.024, PubMed 33899743

Lindholm E, Tonnessen TI (2020)
Prolonged illness after covid-19
Tidsskr. Nor. Laegeforen., 140 (14), 1433-1435

Lindholm E, Tønnessen TI (2020)
Prolonged illness after COVID-19
Tidsskr Nor Laegeforen, 140 (14)
DOI 10.4045/tidsskr.20.0753, PubMed 33070586

Lindholm E, Tønnessen TI (2020)
[Correction: Prolonged illness after COVID-19]
Tidsskr Nor Laegeforen, 140 (16)
DOI 10.4045/tidsskr.20.0831, PubMed 33172247

Lipcsey M, Tenhunen J, Pischke SE, Kuitunen A, Flaatten H, De Geer L, Sjölin J, Frithiof R, Chew MS, Bendel S, Kawati R, Larsson A, Mollnes TE, Tønnessen TI, Rubertsson S (2020)
Endotoxin Removal in Septic Shock with the Alteco LPS Adsorber Was Safe But Showed no Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial-the Asset Study
Shock, 54 (2), 224-231
DOI 10.1097/SHK.0000000000001503, PubMed 31880758

Pischke SE, Hødnebø S, Wester T, Haugaa H, Kvernebo K, Barratt-Due A, Tønnessen TI (2020)
Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model
Scand J Gastroenterol, 56 (2), 219-227
DOI 10.1080/00365521.2020.1863459, PubMed 33356757

Schalit I, Espinoza A, Pettersen FJ, Snartland S, Ringdal ML, Hoel TN, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2020)
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J, 66 (1), 38-48
DOI 10.1097/MAT.0000000000000954, PubMed 30688692

Stens NA, Hisdal J, Bakke EF, Kaur N, Sharma A, Stranden E, Thijssen DHJ, Høiseth LØ (2020)
Factors mediating the pressor response to isometric muscle contraction: An experimental study in healthy volunteers during lower body negative pressure
PLoS One, 15 (12), e0243627
DOI 10.1371/journal.pone.0243627, PubMed 33296410

Sun X, Zhu S, Tonnessen TI, Yang R (2020)
Bile is a promising gut nutrient that inhibits intestinal bacterial translocation and promotes gut motility via an interleukin-6-related pathway in an animal model of endotoxemia
Nutrition, 84, 111064
DOI 10.1016/j.nut.2020.111064, PubMed 33418232

Wisløff-Aase K, Kerans V, Haugaa K, Halvorsen PS, Skulstad H, Espinoza A (2020)
Changes in left ventricular electromechanical relations during targeted hypothermia
Intensive Care Med Exp, 8 (1), 76
DOI 10.1186/s40635-020-00363-7, PubMed 33315166

Dahle G, Helle-Valle T, Beitnes JO, Espinoza A, Halvorsen PS, Rein KA (2019)
Single-centre first experience with transapical transcatheter mitral valve replacement with an apical tether: factors influencing screening outcomes
Interact Cardiovasc Thorac Surg, 28 (5), 695-703
DOI 10.1093/icvts/ivy343, PubMed 30602024

Hausken J, Fretland ÅA, Edwin B, Andersen MH, Dagenborg VJ, Bjørnelv GMW, Kristiansen R, Røysland K, Kvarstein G, Tønnessen TI (2019)
Intravenous Patient-controlled Analgesia Versus Thoracic Epidural Analgesia After Open Liver Surgery: A Prospective, Randomized, Controlled, Noninferiority Trial
Ann Surg, 270 (2), 193-199
DOI 10.1097/SLA.0000000000003209, PubMed 30676382

Hausken J, Rydenfelt K, Horneland R, Ullensvang K, Kjøsen G, Tønnessen TI, Haugaa H (2019)
First Experience With Rectus Sheath Block for Postoperative Analgesia After Pancreas Transplant: A Retrospective Observational Study
Transplant Proc, 51 (2), 479-484
DOI 10.1016/j.transproceed.2019.01.065, PubMed 30879572

Hisdal J, Landsverk SA, Hoff IE, Hagen OA, Kirkebøen KA, Høiseth LØ (2019)
Associations between changes in precerebral blood flow and cerebral oximetry in the lower body negative pressure model of hypovolemia in healthy volunteers
PLoS One, 14 (6), e0219154
DOI 10.1371/journal.pone.0219154, PubMed 31251778

Hisdal J, Landsverk SA, Hoff IE, Hagen OA, Kirkebøen KA, Høiseth LØ (2019)
Correction: Associations between changes in precerebral blood flow and cerebral oximetry in the lower body negative pressure model of hypovolemia in healthy volunteers
PLoS One, 14 (7), e0220403
DOI 10.1371/journal.pone.0220403, PubMed 31335906

Hoel H, Høiseth LØ, Sandbaek G, Sundhagen JO, Mathiesen I, Hisdal J (2019)
The acute effects of different levels of intermittent negative pressure on peripheral circulation in patients with peripheral artery disease
Physiol Rep, 7 (20), e14241
DOI 10.14814/phy2.14241, PubMed 31631579

Hoff IE, Hisdal J, Landsverk SA, Røislien J, Kirkebøen KA, Høiseth LØ (2019)
Respiratory variations in pulse pressure and photoplethysmographic waveform amplitude during positive expiratory pressure and continuous positive airway pressure in a model of progressive hypovolemia
PLoS One, 14 (9), e0223071
DOI 10.1371/journal.pone.0223071, PubMed 31560715

Hoff IE, Høiseth LØ, Kirkebøen KA, Landsverk SA (2019)
Volumetric and End-Tidal Capnography for the Detection of Cardiac Output Changes in Mechanically Ventilated Patients Early after Open Heart Surgery
Crit Care Res Pract, 2019, 6393649
DOI 10.1155/2019/6393649, PubMed 31281675

Kjønås D, Dahle G, Schirmer H, Malm S, Eidet J, Aaberge L, Steigen T, Aakhus S, Busund R, Rösner A (2019)
Predictors of early mortality after transcatheter aortic valve implantation
Open Heart, 6 (1), e000936
DOI 10.1136/openhrt-2018-000936, PubMed 31168372

Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW (2019)
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004

Bergan HA, Halvorsen PS, Espinoza A, Kerans V, Skulstad H, Fosse E, Bugge JF (2018)
Left Ventricle Function During Therapeutic Hypothermia with Beta₁-Adrenergic Receptor Blockade
Ther Hypothermia Temp Manag, 8 (3), 156-164
DOI 10.1089/ther.2017.0051, PubMed 29394143

Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B (2018)
Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial
Ann Surg, 267 (2), 199-207
DOI 10.1097/SLA.0000000000002353, PubMed 28657937

Holhjem L, Strand-Amundsen R, Aasmundtveit KE, Tonnessen TI (2018)
Stability of Laser-Patterned Electrode Compositions
IEEE Trans. Compon. Pack. Manuf. Technol., 8 (9), 1517-1523
DOI 10.1109/TCPMT.2018.2863221

Hyler S, Espinoza A, Skulstad H, Fosse E, Steinar Halvorsen P (2018)
Corrigendum to 'Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor' [Eur J Cardiothorac Surg 2014;46:313-20]
Eur J Cardiothorac Surg, 54 (5), 968
DOI 10.1093/ejcts/ezy340, PubMed 30295773

Laake JH, Tønnessen TI, Chew MS, Lipcsey M, Hjelmqvist H, Wilkman E, Pettilä V, Hoffmann-Petersen J, Møller MH, Board of the Scandinavian Society of Anaesthesiology Intensive Care Medicine (SSAI) (2018)
The SSAI fully supports the suspension of hydroxyethyl-starch solutions commissioned by the European Medicines Agency
Acta Anaesthesiol Scand, 62 (6), 874-875
DOI 10.1111/aas.13120, PubMed 29658984

Ottestad W, Kåsin JI, Høiseth LØ (2018)
Arterial Oxygen Saturation, Pulse Oximetry, and Cerebral and Tissue Oximetry in Hypobaric Hypoxia
Aerosp Med Hum Perform, 89 (12), 1045-1049
DOI 10.3357/AMHP.5173.2018, PubMed 30487024

Schalit I, Espinoza A, Pettersen FJ, Thiara APS, Karlsen H, Sørensen G, Fosse E, Fiane AE, Halvorsen PS (2018)
Accelerometer Detects Pump Thrombosis and Thromboembolic Events in an In vitro HVAD Circuit
ASAIO J, 64 (5), 601-609
DOI 10.1097/MAT.0000000000000699, PubMed 29088023

Stafseth SK, Tønnessen TI, Fagerström L (2018)
Association between patient classification systems and nurse staffing costs in intensive care units: An exploratory study
Intensive Crit Care Nurs, 45, 78-84
DOI 10.1016/j.iccn.2018.01.007, PubMed 29402682

Stafseth SK, Tønnessen TI, My Diep L, Fagerstrøm L (2018)
Testing the Reliability and Validity of the Nursing Activities Score in Critical Care Nursing
J Nurs Meas, 26 (1), 142-162
DOI 10.1891/1061-3749.26.1.142, PubMed 29724285

Strand-Amundsen RJ, Reims HM, Reinholt FP, Ruud TE, Yang R, Høgetveit JO, Tønnessen TI (2018)
Ischemia/reperfusion injury in porcine intestine - Viability assessment
World J Gastroenterol, 24 (18), 2009-2023
DOI 10.3748/wjg.v24.i18.2009, PubMed 29760544

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Ruud TE, Høgetveit JO, Martinsen ØG, Tønnessen TI (2018)
Small intestinal ischemia and reperfusion-bioimpedance measurements
Physiol Meas, 39 (2), 025001
DOI 10.1088/1361-6579/aaa576, PubMed 29303488

Strand-Amundsen RJ, Tronstad C, Reims HM, Reinholt FP, Høgetveit JO, Tønnessen TI (2018)
Machine learning for intraoperative prediction of viability in ischemic small intestine
Physiol Meas, 39 (10), 105011
DOI 10.1088/1361-6579/aae0ea, PubMed 30207981

Sundby ØH, Irgens I, Høiseth LØ, Mathiesen I, Lundgaard E, Haugland H, Weedon-Fekjær H, Sundhagen JO, Sandbæk G, Hisdal J (2018)
Intermittent mild negative pressure applied to the lower limb in patients with spinal cord injury and chronic lower limb ulcers: a crossover pilot study
Spinal Cord, 56 (4), 372-381
DOI 10.1038/s41393-018-0080-4, PubMed 29497177

Yang R, Zhu S, Pischke SE, Haugaa H, Zou X, Tonnessen TI (2018)
Bile and circulating HMGB1 contributes to systemic inflammation in obstructive jaundice
J Surg Res, 228, 14-19
DOI 10.1016/j.jss.2018.02.049, PubMed 29907203

Grymyr OH, Beitnes JO, Eidet J, Tølløfsrud S, Fiane A, Skulstad H, Fosse E, Halvorsen PS (2017)
Detection of intraoperative myocardial dysfunction by accelerometer during aortic valve replacement
Interact Cardiovasc Thorac Surg, 24 (2), 188-195
DOI 10.1093/icvts/ivw326, PubMed 28364479

Høiseth LØ, Hagemo JS (2017)
Predicting fluid responsiveness in whom? A simulated example of patient spectrum influencing the receiver operating characteristics curve
J Clin Monit Comput, 32 (2), 215-219
DOI 10.1007/s10877-017-0019-x, PubMed 28432561

Ottestad W, Hansen TA, Pradhan G, Stepanek J, Høiseth LØ, Kåsin JI (2017)
Acute hypoxia in a simulated high-altitude airdrop scenario due to oxygen system failure
J Appl Physiol (1985), 123 (6), 1443-1450
DOI 10.1152/japplphysiol.00169.2017, PubMed 28839003

Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE (2017)
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
Basic Res Cardiol, 112 (3), 20
DOI 10.1007/s00395-017-0610-9, PubMed 28258298

Strand-Amundsen RJ, Reims HM, Tronstad C, Kalvøy H, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2017)
Ischemic small intestine-in vivo versus ex vivo bioimpedance measurements
Physiol Meas, 38 (5), 715-728
DOI 10.1088/1361-6579/aa67b7, PubMed 28319030

Sundby ØH, Høiseth LØ, Irgens I, Mathiesen I, Lundgaard E, Haugland H, Weedon-Fekjær H, Sundhagen JO, Sanbæk G, Hisdal J (2017)
Intermittent negative pressure applied to the lower limb increases foot macrocirculatory and microcirculatory blood flow pulsatility in people with spinal cord injury
Spinal Cord, 56 (4), 382-391
DOI 10.1038/s41393-017-0049-8, PubMed 29284796

Sundby ØH, Høiseth LØ, Mathiesen I, Weedon-Fekjær H, Sundhagen JO, Hisdal J (2017)
The acute effects of lower limb intermittent negative pressure on foot macro- and microcirculation in patients with peripheral arterial disease
PLoS One, 12 (6), e0179001
DOI 10.1371/journal.pone.0179001, PubMed 28591174

Yang R, Tenhunen J, Tonnessen TI (2017)
HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis
Int J Inflam, 2017, 1817564
DOI 10.1155/2017/1817564, PubMed 28316860

Yang R, Zou X, Tenhunen J, Tønnessen TI (2017)
HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure
Mediators Inflamm, 2017, 5928078
DOI 10.1155/2017/5928078, PubMed 28694564

Bugge JF, Espinoza A, Halvorsen PS (2016)
Hypothermia Is Not an Inotropic Drug
Crit Care Med, 44 (12), e1258
DOI 10.1097/CCM.0000000000002048, PubMed 27858830

Eidet J, Dahle G, Bugge JF, Bendz B, Rein KA, Aaberge L, Offstad JT, Fosse E, Aakhus S, Halvorsen PS (2016)
Long-term outcomes after transcatheter aortic valve implantation: the impact of intraoperative tissue Doppler echocardiography
Interact Cardiovasc Thorac Surg, 23 (3), 403-9
DOI 10.1093/icvts/ivw159, PubMed 27241050

Grindheim G, Eidet J, Bentsen G (2016)
Transpulmonary thermodilution (PiCCO) measurements in children without cardiopulmonary dysfunction: large interindividual variation and conflicting reference values
Paediatr Anaesth, 26 (4), 418-24
DOI 10.1111/pan.12859, PubMed 26857433

Høiseth LØ, Hagemo JS (2016)
Comparing measurement methods using linear least squares regression
J Clin Monit Comput, 32 (2), 373-374
DOI 10.1007/s10877-016-9955-0, PubMed 27837298

Lipcsey M, Tenhunen J, Sjölin J, Frithiof R, Bendel S, Flaatten H, Kawati R, Kuitunen A, Tønnessen TI, Rubertsson S (2016)
Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco® LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial
Trials, 17 (1), 587
DOI 10.1186/s13063-016-1723-4, PubMed 27931259

Rimehaug AE, Hoff IE, Høiseth LØ, Hisdal J, Aadahl P, Kirkeby-Garstad I (2016)
Cardiac power parameters during hypovolemia, induced by the lower body negative pressure technique, in healthy volunteers
BMC Anesthesiol, 16 (1), 31
DOI 10.1186/s12871-016-0195-0, PubMed 27364749

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Gundersen Y, Krohn CD, Aasen AO, Holhjem L, Reims HM, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2016)
In vivo characterization of ischemic small intestine using bioimpedance measurements
Physiol Meas, 37 (2), 257-75
DOI 10.1088/0967-3334/37/2/257, PubMed 26805916

Sundby ØH, Høiseth LØ, Mathiesen I, Jørgensen JJ, Sundhagen JO, Hisdal J (2016)
The effects of intermittent negative pressure on the lower extremities' peripheral circulation and wound healing in four patients with lower limb ischemia and hard-to-heal leg ulcers: a case report
Physiol Rep, 4 (20)
DOI 10.14814/phy2.12998, PubMed 27798353

Sundby ØH, Høiseth LØ, Mathiesen I, Jørgensen JJ, Weedon-Fekjær H, Hisdal J (2016)
Application of intermittent negative pressure on the lower extremity and its effect on macro- and microcirculation in the foot of healthy volunteers
Physiol Rep, 4 (17)
DOI 10.14814/phy2.12911, PubMed 27630148

Tønnessen TI (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (5), 380-1
DOI 10.4045/tidsskr.16.0171, PubMed 26983125

Yang R, Zhu S, Tonnessen TI (2016)
Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries
J Inflamm (Lond), 13, 37
DOI 10.1186/s12950-016-0144-1, PubMed 27980458

Eidet J, Dahle G, Bugge JF, Bendz B, Rein KA, Fosse E, Aakhus S, Halvorsen PS (2015)
Transcatheter aortic valve implantation and intraoperative left ventricular function: a myocardial tissue Doppler imaging study
J Cardiothorac Vasc Anesth, 29 (1), 115-20
DOI 10.1053/j.jvca.2014.10.016, PubMed 25620143

Eidet J, Dahle G, Bugge JF, Bendz B, Rein KA, Aaberge L, Offstad JT, Fosse E, Aakhus S, Halvorsen PS (2015)
Intraoperative improvement in left ventricular peak systolic velocity predicts better short-term outcome after transcatheter aortic valve implantation
Interact Cardiovasc Thorac Surg, 22 (1), 5-12
DOI 10.1093/icvts/ivv277, PubMed 26467639

Espinoza A, Neumann K, Halvorsen PS, Sundset A, Kongerud J, Fosse E (2015)
Critical airway obstruction: challenges in airway management and ventilation during therapeutic bronchoscopy
J Bronchology Interv Pulmonol, 22 (1), 41-7
DOI 10.1097/LBR.0000000000000127, PubMed 25590482

Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
DOI 10.1186/s13063-015-0577-5, PubMed 25872027

Grymyr OJ, Nguyen AT, Tjulkins F, Espinoza A, Remme EW, Skulstad H, Fosse E, Imenes K, Halvorsen PS (2015)
Continuous monitoring of cardiac function by 3-dimensional accelerometers in a closed-chest pig model
Interact Cardiovasc Thorac Surg, 21 (5), 573-82
DOI 10.1093/icvts/ivv191, PubMed 26254463

Hagen OA, Høiseth LØ, Roslin A, Landsverk SA, Woldbaek PR, Pripp AH, Hanoa R, Kirkebøen KA (2015)
Impact of Norepinephrine on Regional Cerebral Oxygenation During Cardiopulmonary Bypass
J Cardiothorac Vasc Anesth, 30 (2), 291-6
DOI 10.1053/j.jvca.2015.12.015, PubMed 27013119

Haugaa H, Gómez H, Maberry DR, Holder A, Ogundele O, Quintero AM, Escobar D, Tønnessen TI, Airgood H, Dezfulian C, Kenny E, Shiva S, Zuckerbraun B, Pinsky MR (2015)
Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine
Crit Care, 19 (1), 184
DOI 10.1186/s13054-015-0903-z, PubMed 25899004

Hyler S, Pischke SE, Halvorsen PS, Espinoza A, Bergsland J, Tønnessen TI, Fosse E, Skulstad H (2015)
Continuous monitoring of regional function by a miniaturized ultrasound transducer allows early quantification of low-grade myocardial ischemia
J Am Soc Echocardiogr, 28 (4), 486-94
DOI 10.1016/j.echo.2014.12.014, PubMed 25636368

Høiseth LØ, Hisdal J, Hoff IE, Hagen OA, Landsverk SA, Kirkebøen KA (2015)
Tissue oxygen saturation and finger perfusion index in central hypovolemia: influence of pain
Crit Care Med, 43 (4), 747-56
DOI 10.1097/CCM.0000000000000766, PubMed 25513787

Høiseth LØ, Hisdal J, Landsverk SA, Kirkebøen KA (2015)
The authors reply
Crit Care Med, 43 (10), e463-4
DOI 10.1097/CCM.0000000000001206, PubMed 26376266

Høiseth LØ, Hoff IE, Hagen OA, Kirkebøen KA, Landsverk SA (2015)
Respiratory variations in the photoplethysmographic waveform amplitude depend on type of pulse oximetry device
J Clin Monit Comput, 30 (3), 317-25
DOI 10.1007/s10877-015-9720-9, PubMed 26067403

Høiseth LØ, Hoff IE, Hagen OA, Landsverk SA, Kirkebøen KA (2015)
Agreement between stroke volume measured by oesophageal Doppler and uncalibrated pulse contour analysis during fluid loads in severe aortic stenosis
J Clin Monit Comput, 29 (4), 435-41
DOI 10.1007/s10877-015-9666-y, PubMed 25638514

Kerans V, Espinoza A, Skulstad H, Halvorsen PS, Edvardsen T, Bugge JF (2015)
Systolic left ventricular function is preserved during therapeutic hypothermia, also during increases in heart rate with impaired diastolic filling
Intensive Care Med Exp, 3 (1), 41
DOI 10.1186/s40635-015-0041-6, PubMed 26215808

Khan F, Pharo A, Lindstad JK, Mollnes TE, Tønnessen TI, Pischke SE (2015)
Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis
Scand J Immunol, 82 (5), 467-75
DOI 10.1111/sji.12332, PubMed 26099791

Espinoza A, Edvardsen T (2014)
Mechanisms of QT prolongation during hypothermia
J Am Soc Echocardiogr, 27 (6), 680-1
DOI 10.1016/j.echo.2014.04.003, PubMed 24774223

Grymyr OJ, Remme EW, Espinoza A, Skulstad H, Elle OJ, Fosse E, Halvorsen PS (2014)
Assessment of 3D motion increases the applicability of accelerometers for monitoring left ventricular function
Interact Cardiovasc Thorac Surg, 20 (3), 329-37
DOI 10.1093/icvts/ivu404, PubMed 25472979

Haugaa H, Taraldsrud E, Nyrerød HC, Tønnessen TI, Foss A, Solheim BG (2014)
Low incidence of hyperfibrinolysis and thromboembolism in 195 primary liver transplantations transfused with solvent/detergent-treated plasma
Clin Med Res, 12 (1-2), 27-32
DOI 10.3121/cmr.2013.1168, PubMed 24415744

Hestenes SM, Halvorsen PS, Skulstad H, Remme EW, Espinoza A, Hyler S, Bugge JF, Fosse E, Nielsen EW, Edvardsen T (2014)
Advantages of strain echocardiography in assessment of myocardial function in severe sepsis: an experimental study
Crit Care Med, 42 (6), e432-40
DOI 10.1097/CCM.0000000000000310, PubMed 24633187

Hoff IE, Høiseth LØ, Hisdal J, Røislien J, Landsverk SA, Kirkebøen KA (2014)
Respiratory Variations in Pulse Pressure Reflect Central Hypovolemia during Noninvasive Positive Pressure Ventilation
Crit Care Res Pract, 2014, 712728
DOI 10.1155/2014/712728, PubMed 24696781

Hyler S, Espinoza A, Skulstad H, Fosse E, Halvorsen PS (2014)
Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor
Eur J Cardiothorac Surg, 46 (2), 313-20
DOI 10.1093/ejcts/ezt653, PubMed 24482390

Høiseth LØ, Hoff IE, Hagen OA, Landsverk SA, Kirkebøen KA (2014)
Dynamic variables and fluid responsiveness in patients for aortic stenosis surgery
Acta Anaesthesiol Scand, 58 (7), 826-34
DOI 10.1111/aas.12328, PubMed 24773498

Pischke SE, Hyler S, Tronstad C, Bergsland J, Fosse E, Halvorsen PS, Skulstad H, Tønnessen TI (2014)
Myocardial tissue CO2 tension detects coronary blood flow reduction after coronary artery bypass in real-time†
Br J Anaesth, 114 (3), 414-22
DOI 10.1093/bja/aeu381, PubMed 25392231

Yang R, Zou X, Tenhunen J, Zhu S, Kajander H, Koskinen ML, Tonnessen TI (2014)
HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity
BMC Gastroenterol, 14, 66
DOI 10.1186/1471-230X-14-66, PubMed 24708589

Espinoza A, Kerans V, Opdahl A, Skulstad H, Halvorsen PS, Bugge JF, Fosse E, Edvardsen T (2013)
Effects of therapeutic hypothermia on left ventricular function assessed by ultrasound imaging
J Am Soc Echocardiogr, 26 (11), 1353-63
DOI 10.1016/j.echo.2013.06.021, PubMed 23891124

Haugaa H, Almaas R, Thorgersen EB, Foss A, Line PD, Sanengen T, Bergmann GB, Ohlin P, Waelgaard L, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2013)
Clinical experience with microdialysis catheters in pediatric liver transplants
Liver Transpl, 19 (3), 305-14
DOI 10.1002/lt.23578, PubMed 23193034

Holhjem L, Strand-Amundsen R, Aasmundtveit KE, Tonnessen TI (2013)
Development of a Conductometric Biocompatible Sensor For Detecting Ischemia
EUR MICROELECTRON PA

Neumann K, Sundset A, Espinoza A, Kongerud J, Fosse E (2013)
Changes in quality of life, dyspnea scores, and lung function in lung cancer patients with airway obstruction after a therapeutic bronchoscopy
J Bronchology Interv Pulmonol, 20 (2), 134-9
DOI 10.1097/LBR.0b013e3182917280, PubMed 23609247

Espinoza A, Bergsland J, Lundblad R, Fosse E (2012)
Wide sternal retraction may impede internal mammary artery graft flow and reduce myocardial function during off-pump coronary artery bypass grafting: presentation of two cases
Interact Cardiovasc Thorac Surg, 15 (1), 42-4
DOI 10.1093/icvts/ivs135, PubMed 22499803

Høiseth LØ, Hoff IE, Myre K, Landsverk SA, Kirkebøen KA (2012)
Dynamic variables of fluid responsiveness during pneumoperitoneum and laparoscopic surgery
Acta Anaesthesiol Scand, 56 (6), 777-86
DOI 10.1111/j.1399-6576.2011.02641.x, PubMed 22288953

Håugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2012)
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transpl, 18 (7), 839-49
DOI 10.1002/lt.23425, PubMed 22407878

Neyman K, Sundset A, Naalsund A, Espinoza A, Solberg S, Kongerud J, Fosse E (2012)
Endoscopic treatment of bronchial carcinoids in comparison to surgical resection: a retrospective study
J Bronchology Interv Pulmonol, 19 (1), 29-34
DOI 10.1097/LBR.0b013e3182446b52, PubMed 23207260

Pischke SE, Tronstad C, Holhjem L, Halvorsen PS, Tønnessen TI (2012)
Perioperative detection of myocardial ischaemia/reperfusion with a novel tissue CO2 monitoring technology
Eur J Cardiothorac Surg, 42 (1), 157-63
DOI 10.1093/ejcts/ezr278, PubMed 22290904

Pischke SE, Tronstad C, Holhjem L, Line PD, Haugaa H, Tønnessen TI (2012)
Hepatic and abdominal carbon dioxide measurements detect and distinguish hepatic artery occlusion and portal vein occlusion in pigs
Liver Transpl, 18 (12), 1485-94
DOI 10.1002/lt.23544, PubMed 22961940

Sokolov A, Hellerud BC, Tønnessen TI, Johannessen EA, Mollnes TE (2012)
Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant
J Biomed Mater Res A, 101 (2), 575-81
DOI 10.1002/jbm.a.34348, PubMed 22949225

Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
Shock, 36 (5), 517-23
DOI 10.1097/SHK.0b013e3182336a34, PubMed 21921836

Espinoza A, Rosseland LA, Hovdenes J, Stubhaug A (2011)
Paratracheal placement of orotracheal tube: a complication when aborting percutaneous tracheotomy
Acta Anaesthesiol Scand, 55 (7), 897-8
DOI 10.1111/j.1399-6576.2011.02438.x, PubMed 21749335

Høiseth LØ, Hoff IE, Skare O, Kirkebøen KA, Landsverk SA (2011)
Photoplethysmographic and pulse pressure variations during abdominal surgery
Acta Anaesthesiol Scand, 55 (10), 1221-30
DOI 10.1111/j.1399-6576.2011.02527.x, PubMed 22092127

Krushinitskaya O, Tonnessen TI, Jakobsen H, Johannessen EA (2011)
Characterization of nanoporous membranes for implementation in an osmotic glucose sensor based on the concanavalin A-dextran affinity assay
J. Membr. Sci., 376 (1-2), 153-161
DOI 10.1016/j.memsci.2011.04.009

Krushinitskaya O, Tønnessen TI, Jakobsen H, Johannessen E (2011)
The assessment of potentially interfering metabolites and dietary components in blood using an osmotic glucose sensor based on the concanavalin A-dextran affinity assay
Biosens Bioelectron, 28 (1), 195-203
DOI 10.1016/j.bios.2011.07.019, PubMed 21816599

Neyman K, Sundset A, Espinoza A, Kongerud J, Fosse E (2011)
Survival and complications after interventional bronchoscopy in malignant central airway obstruction: a single-center experience
J Bronchology Interv Pulmonol, 18 (3), 233-8
DOI 10.1097/LBR.0b013e318222a7da, PubMed 23208566

Waelgaard L, Dahl BM, Kvarstein G, Tønnessen TI (2011)
Tissue gas tensions and tissue metabolites for detection of organ hypoperfusion and ischemia
Acta Anaesthesiol Scand, 56 (2), 200-9
DOI 10.1111/j.1399-6576.2011.02572.x, PubMed 22103593

Espinoza A, Halvorsen PS, Skulstad H, Lundblad R, Bugge JF, Hoff L, Fosse E, Edvardsen T (2010)
Automated detection of myocardial ischaemia by epicardial miniature ultrasound transducers--a novel tool for patient monitoring during cardiac surgery
Eur J Cardiothorac Surg, 39 (1), 53-9
DOI 10.1016/j.ejcts.2010.03.067, PubMed 20627751

Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tønnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P (2010)
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis
Crit Care Med, 38 (6), 1467-74
DOI 10.1097/CCM.0b013e3181de8c94, PubMed 20400898

Johannessen E, Krushinitskaya O, Sokolov A, Philipp H, Hoogerwerf A, Hinderling C, Kautio K, Lenkkeri J, Strömmer E, Kondratyev V, Tønnessen TI, Mollnes TE, Jakobsen H, Zimmer E, Akselsen B (2010)
Toward an injectable continuous osmotic glucose sensor
J Diabetes Sci Technol, 4 (4), 882-92
DOI 10.1177/193229681000400417, PubMed 20663452

Tronstad C, Pischke SE, Holhjem L, Tønnessen TI, Martinsen OG, Grimnes S (2010)
Early detection of cardiac ischemia using a conductometric pCO(2) sensor: real-time drift correction and parameterization
Physiol Meas, 31 (9), 1241-55
DOI 10.1088/0967-3334/31/9/013, PubMed 20702916

Espinoza A, Halvorsen PS, Hoff L, Skulstad H, Fosse E, Ihlen H, Edvardsen T (2009)
Detecting myocardial ischaemia using miniature ultrasonic transducers--a feasibility study in a porcine model
Eur J Cardiothorac Surg, 37 (1), 119-26
DOI 10.1016/j.ejcts.2009.05.013, PubMed 19581103

Halvorsen PS, Remme EW, Espinoza A, Skulstad H, Lundblad R, Bergsland J, Hoff L, Imenes K, Edvardsen T, Elle OJ, Fosse E (2009)
Automatic real-time detection of myocardial ischemia by epicardial accelerometer
J Thorac Cardiovasc Surg, 139 (4), 1026-32
DOI 10.1016/j.jtcvs.2009.05.031, PubMed 19717169

Kvarstein G, Måwe L, Indahl A, Hol PK, Tennøe B, Digernes R, Stubhaug A, Tønnessen TI, Beivik H (2009)
A randomized double-blind controlled trial of intra-annular radiofrequency thermal disc therapy--a 12-month follow-up
Pain, 145 (3), 279-286
DOI 10.1016/j.pain.2009.05.001, PubMed 19647940

Kvarstein G, Måwe L, Indahl A, Hol PK, Tennøe B, Digernes R, Tønnessen TI, Beivik H, Stubhaug A (2009)
Placebo control--still the most ethical study design
Pain, 148 (1), 174-175
DOI 10.1016/j.pain.2009.11.013, PubMed 19962241

Landsverk SA, Hoiseth LO, Kirkeboen KA (2009)
Oscillations in the Plethysmographic Waveform Amplitude: Phenomenon Hides Behind Artifacts Reply
Anesthesiology, 111 (1), 207-208
DOI 10.1097/ALN.0b013e3181a96055

Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE (2009)
A new dynamic porcine model of meningococcal shock
Shock, 32 (3), 302-9
DOI 10.1097/SHK.0b013e31819c37be, PubMed 19174740

Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
FASEB J, 24 (3), 712-22
DOI 10.1096/fj.09-140798, PubMed 19841036

Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, Gaustad P, Brun H, Fosse E, Tønnessen TI, Nielsen EW, Mollnes TE (2008)
New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs
Scand J Immunol, 68 (1), 75-84
DOI 10.1111/j.1365-3083.2008.02122.x, PubMed 18466195

Halvorsen PS, Espinoza A, Fleischer LA, Elle OJ, Hoff L, Lundblad R, Skulstad H, Edvardsen T, Ihlen H, Fosse E (2008)
Feasibility of a three-axis epicardial accelerometer in detecting myocardial ischemia in cardiac surgical patients
J Thorac Cardiovasc Surg, 136 (6), 1496-502
DOI 10.1016/j.jtcvs.2008.08.043, PubMed 19114197

Hoff L, Espinoza A, Ihlen H (2008)
Cardiac Monitoring Using Transducers Attached Directly to the Heart
ULTRASON, 749-+
DOI 10.1109/ULTSYM.2008.0179

Landsverk SA, Hoiseth LO, Kvandal P, Hisdal J, Skare O, Kirkeboen KA (2008)
Poor agreement between respiratory variations in pulse oximetry photoplethysmographic waveform amplitude and pulse pressure in intensive care unit patients
Anesthesiology, 109 (5), 849-55
DOI 10.1097/ALN.0b013e3181895f9f, PubMed 18946297

Waelgaard L, Thorgersen EB, Line PD, Foss A, Mollnes TE, Tønnessen TI (2008)
Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation
Transplantation, 86 (8), 1096-103
DOI 10.1097/TP.0b013e31818775ca, PubMed 18946348

Andersen MH, Mathisen L, Veenstra M, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2007)
Quality of life after randomization to laparoscopic versus open living donor nephrectomy: long-term follow-up
Transplantation, 84 (1), 64-9
DOI 10.1097/01.tp.0000268071.63977.42, PubMed 17627239

Halvorsen PS, Sokolov A, Cvancarova M, Hol PK, Lundblad R, Tønnessen TI (2007)
Continuous cardiac output during off-pump coronary artery bypass surgery: pulse-contour analyses vs pulmonary artery thermodilution
Br J Anaesth, 99 (4), 484-92
DOI 10.1093/bja/aem199, PubMed 17650518

Andersen MH, Mathisen L, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2006)
Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
Am J Transplant, 6 (6), 1438-43
DOI 10.1111/j.1600-6143.2006.01301.x, PubMed 16686768

Halvorsen PS, Espinoza A, Lundblad R, Cvancarova M, Hol PK, Fosse E, Tønnessen TI (2006)
Agreement between PiCCO pulse-contour analysis, pulmonal artery thermodilution and transthoracic thermodilution during off-pump coronary artery by-pass surgery
Acta Anaesthesiol Scand, 50 (9), 1050-7
DOI 10.1111/j.1399-6576.2006.01118.x, PubMed 16987335

Høiseth LØ, Giercksky KE, Larsen SG, Kongsgaard U (2006)
[Major surgery on Jehovah's Witnesses]
Tidsskr Nor Laegeforen, 126 (20), 2658-61
PubMed 17057765

Waelgaard L, Pharo A, Tønnessen TI, Mollnes TE (2006)
Microdialysis for monitoring inflammation: efficient recovery of cytokines and anaphylotoxins provided optimal catheter pore size and fluid velocity conditions
Scand J Immunol, 64 (3), 345-52
DOI 10.1111/j.1365-3083.2006.01826.x, PubMed 16918704

Mathisen L, Andersen MH, Hol PK, Lingaas PS, Lundblad R, Rein KA, Tønnessen TI, Mørk BE, Svennevig JL, Wahl AK, Hanestad BR, Fosse E (2005)
Patient-reported outcome after randomization to on-pump versus off-pump coronary artery surgery
Ann Thorac Surg, 79 (5), 1584-9
DOI 10.1016/j.athoracsur.2004.10.019, PubMed 15854937

Kvarstein G, Mirtaheri P, Tønnessen TI (2004)
Detection of ischemia by PCO2 before adenosine triphosphate declines in skeletal muscle
Crit Care Med, 32 (1), 232-7
DOI 10.1097/01.CCM.0000104948.41544.FC, PubMed 14707584

Mirtaheri P, Grimnes S, Martinsen OG, Tønnessen TI (2004)
A new biomedical sensor for measuring PCO2
Physiol Meas, 25 (2), 421-36
DOI 10.1088/0967-3334/25/2/002, PubMed 15132308

Mirtaheri P, Omtveit T, Klotzbuecher T, Grimnes S, Martinsen OG, Tønnessen TI (2004)
Miniaturization of a biomedical gas sensor
Physiol Meas, 25 (6), 1511-22
DOI 10.1088/0967-3334/25/6/015, PubMed 15712728

Skulstad H, Andersen K, Edvardsen T, Rein KA, Tønnessen TI, Hol PK, Fosse E, Ihlen H (2004)
Detection of ischemia and new insight into left ventricular physiology by strain Doppler and tissue velocity imaging: assessment during coronary bypass operation of the beating heart
J Am Soc Echocardiogr, 17 (12), 1225-33
DOI 10.1016/j.echo.2004.07.014, PubMed 15562259

Bjørnstad PG, Smevik B, Holmstrøm H, Thaulow E, Hagemo PS, Ihlen H, Bjørnerheim R, Lindberg HL, Seem E, Tønnessen TI, Hustveit O, Fosse E (2003)
[Transcatheter closure of atrial septal defects in the oval fossa]
Tidsskr Nor Laegeforen, 123 (15), 2052-4
PubMed 12934130

Kvarstein G, Barstad M, Mirtaheri P, Tønnessen TI (2003)
Tissue carbon dioxide tension: a putative specific indicator of ischemia in porcine latissimus dorsi flaps
Plast Reconstr Surg, 112 (7), 1825-31
DOI 10.1097/01.PRS.0000091166.83956.39, PubMed 14663226

Kvarstein G, Mirtaheri P, Tønnessen TI (2003)
Detection of organ ischemia during hemorrhagic shock
Acta Anaesthesiol Scand, 47 (6), 675-86
DOI 10.1034/j.1399-6576.2003.00134.x, PubMed 12803584

Tønnessen TI (2003)
Detection of hypoperfusion: read your patient's hand
Crit Care Med, 31 (9), 2407-8
DOI 10.1097/01.CCM.0000084862.72867.87, PubMed 14501978

Vik-Mo EO, Oltedal L, Hoivik EA, Kleivdal H, Eidet J, Davanger S (2003)
Sec6 is localized to the plasma membrane of mature synaptic terminals and is transported with secretogranin II-containing vesicles
Neuroscience, 119 (1), 73-85
DOI 10.1016/s0306-4522(03)00065-4, PubMed 12763070

Bjørnstad PG, Holmstrøm H, Smevik B, Tønnessen TI, Fosse E (2002)
Transcatheter closure of atrial septal defects in the oval fossa: is the method applicable in small children?
Cardiol Young, 12 (4), 352-6
DOI 10.1017/s1047951100012956, PubMed 12206558

Rasmussen H, Mirtaheri P, Dirven H, Johnsen H, Kvarstein G, Tønnessen TI, Midtvedt T (2002)
PCO(2) in the large intestine of mice, rats, guinea pigs, and dogs and effects of the dietary substrate
J Appl Physiol (1985), 92 (1), 219-24
DOI 10.1152/japplphysiol.00190.2001, PubMed 11744663

Edwin B, Kazaryan AM, Mala T, Pfeffer PF, Tønnessen TI, Fosse E (2001)
Laparoscopic and open surgery for pheochromocytoma
BMC Surg, 1, 2
DOI 10.1186/1471-2482-1-2, PubMed 11580870

Hol PK, Fosse E, Mork BE, Lundblad R, Rein KA, Lingaas PS, Geiran O, Svennevig JL, Tonnessen TI, Nitter-Hauge S, Due-Tonnessen P, Vatne K, Smith HJ (2001)
Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery
Heart Surg Forum, 4 (3), 254-7; discussion 257-8
PubMed 11673148

Kvarstein G, Tønnessen TI (2001)
[Pain--difficult for both laymen and professionals]
Tidsskr Nor Laegeforen, 121 (22), 2577
PubMed 11668750

Lund C, Lundblad R, Fosse E, Tønnessen TI, Sundet K, Brucher R, Russell D (2001)
Ventricular fibrillation during off-pump coronary artery bypass grafting: transcranial Doppler and clinical findings
Cerebrovasc Dis, 12 (2), 139-41
DOI 10.1159/000047693, PubMed 11490108

Fosse E, Elle OJ, Samset E, Johansen M, Røtnes JS, Tønnessen TI, Edwin B (2000)
[Image guided and robotic treatment--the advance of cybernetics in clinical medicine]
Tidsskr Nor Laegeforen, 120 (1), 65-9
PubMed 10815485

Hol PK, Kvarstein G, Viken O, Smedby O, Tønnessen TI (2000)
MRI-guided celiac plexus block
J Magn Reson Imaging, 12 (4), 562-4
DOI 10.1002/1522-2586(200010)12:4<562::aid-jmri7>3.0.co;2-a, PubMed 11042637

Laake JH, Takumi Y, Eidet J, Torgner IA, Roberg B, Kvamme E, Ottersen OP (1999)
Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum
Neuroscience, 88 (4), 1137-51
DOI 10.1016/s0306-4522(98)00298-x, PubMed 10336125

Rasmussen H, Kvarstein G, Johnsen H, Dirven H, Midtvedt T, Mirtaheri P, Tønnessen TI (1999)
Gas supersaturation in the cecal wall of mice due to bacterial CO2 production
J Appl Physiol (1985), 86 (4), 1311-8
DOI 10.1152/jappl.1999.86.4.1311, PubMed 10194217

Barstad RM, Fosse E, Geiran OR, Simonsen S, Vatne K, Andersen K, Tønnessen TI (1998)
Minimally invasive direct coronary artery bypass grafting without cardiopulmonary bypass in combination with intraoperative percutaneous transluminal coronary angioplasty for palliative coronary revascularization in a heart transplant recipient
J Heart Lung Transplant, 17 (6), 629-34
PubMed 9662100

Cardell M, Landsend AS, Eidet J, Wieloch T, Blackstad TW, Ottersen OP (1998)
High resolution immunogold analysis reveals distinct subcellular compartmentation of protein kinase C gamma and delta in rat Purkinje cells
Neuroscience, 82 (3), 709-25
DOI 10.1016/s0306-4522(97)00305-9, PubMed 9483530

Dishart MK, Schlichtig R, Tonnessen TI, Rozenfeld RA, Simplaceanu E, Williams D, Gayowski TJ (1998)
Mitochondrial redox state as a potential detector of liver dysoxia in vivo
J Appl Physiol (1985), 84 (3), 791-7
DOI 10.1152/jappl.1998.84.3.791, PubMed 9480934

Takumi Y, Nagelhus EA, Eidet J, Matsubara A, Usami S, Shinkawa H, Nielsen S, Ottersen OP (1998)
Select types of supporting cell in the inner ear express aquaporin-4 water channel protein
Eur J Neurosci, 10 (12), 3584-95
DOI 10.1046/j.1460-9568.1998.00360.x, PubMed 9875338

Barstad RM, Fosse E, Vatne K, Andersen K, Tønnessen TI, Svennevig JL, Geiran OR (1997)
Intraoperative angiography in minimally invasive direct coronary artery bypass grafting
Ann Thorac Surg, 64 (6), 1835-9
DOI 10.1016/s0003-4975(97)01072-2, PubMed 9436590

Bjørnstad PG, Thaulow E, Smevik B, Michelsen SS, Tønnessen TI, Fosse E (1997)
[Catheter treatment of congenital heart defects. Arterial septal defects and open ductus arteriosus]
Tidsskr Nor Laegeforen, 117 (20), 2961-4
PubMed 9340856

Fosse E, Lilleås F, Røtnes JS, Edwin B, Tønnessen TI, Hafsahl G, Laerum F (1997)
[The intervention center at the Rikshospital. Experiences from the first year of activity]
Tidsskr Nor Laegeforen, 117 (19), 2779-83
PubMed 9312869

Kvarstein G, Tønnessen TI (1997)
[CO2 pressure used in the diagnosis of ischemia]
Tidsskr Nor Laegeforen, 117 (29), 4251-5
PubMed 9441471

Tønnessen TI (1997)
Biological basis for PCO2 as a detector of ischemia
Acta Anaesthesiol Scand, 41 (6), 659-69
DOI 10.1111/j.1399-6576.1997.tb04764.x, PubMed 9241323

Rozenfeld RA, Dishart MK, Tønnessen TI, Schlichtig R (1996)
Methods for detecting local intestinal ischemic anaerobic metabolic acidosis by PCO2
J Appl Physiol (1985), 81 (4), 1834-42
DOI 10.1152/jappl.1996.81.4.1834, PubMed 8904606

Tønnessen TI, Kvarstein G (1996)
PCO2 electrodes at the surface of the kidney detect ischaemia
Acta Anaesthesiol Scand, 40 (5), 510-9
DOI 10.1111/j.1399-6576.1996.tb04481.x, PubMed 8792878

Aas AT, Tønnessen TI, Brun A, Salford LG (1995)
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
J Neurooncol, 24 (2), 171-80
DOI 10.1007/BF01078487, PubMed 7562004

Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
DOI 10.1007/BF01871417, PubMed 2046087

Tønnessen TI, Tveter KJ (1991)
Drug treatment of pain in patients with urological cancers
Scand J Urol Nephrol Suppl, 138, 253-64
PubMed 1785017

Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
DOI 10.1152/ajpcell.1990.258.6.C1117, PubMed 2163200

Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
DOI 10.1002/jcp.1041430125, PubMed 2156872

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
DOI 10.1016/0006-2952(89)90131-7, PubMed 2818647

Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517

Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
DOI 10.1002/jcp.1041310103, PubMed 3571337

Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
DOI 10.1002/jcp.1041320203, PubMed 3624315

Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
DOI 10.1021/bi00384a019, PubMed 3606992

Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
DOI 10.1002/jcp.1041320202, PubMed 3624314

Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
DOI 10.1083/jcb.102.3.967, PubMed 3949885

Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563

Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160

van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
DOI 10.1083/jcb.102.1.37, PubMed 3001103

Tönnessen TI, Nyland H, Aarli JA (1982)
Complement factors and acute phase reactants in the Guillain-Barré syndrome
Eur Neurol, 21 (2), 124-8
DOI 10.1159/000115467, PubMed 6920298