Trygve Holmøy

  • Postdoctoral researcher
 

Publications 2019

Myhr KM, Torkildsen Ø, Lossius A, Bø L, Holmøy T (2019)
B cell depletion in the treatment of multiple sclerosis
Expert Opin Biol Ther, 19 (3), 261-271
DOI 10.1080/14712598.2019.1568407, PubMed 30632834

Publications 2018

Bjornevik K, Myhr KM, Beiske A, Bjerve KS, Holmøy T, Hovdal H, Midgard R, Riise T, Wergeland S, Torkildsen Ø (2018)
α-Linolenic acid is associated with MRI activity in a prospective cohort of multiple sclerosis patients
Mult Scler, 1352458518779925 (in press)
DOI 10.1177/1352458518779925, PubMed 29862891

Holmøy T, Røsjø E, Zetterberg H, Blennow K, Lindstrøm JC, Steffensen LH, Kampman MT (2018)
Vitamin D supplementation and neurofilament light chain in multiple sclerosis
Acta Neurol Scand, 139 (2), 172-176
DOI 10.1111/ane.13037, PubMed 30317548

Holmøy T, Torkildsen Ø, Zarnovicky S (2018)
Extensive Multiple Sclerosis Reactivation after Switching from Fingolimod to Rituximab
Case Rep Neurol Med, 2018, 5190794
DOI 10.1155/2018/5190794, PubMed 30112230

Høglund RA, Polak J, Vartdal F, Holmøy T, Lossius A (2018)
B-cell composition in the blood and cerebrospinal fluid of multiple sclerosis patients treated with dimethyl fumarate
Mult Scler Relat Disord, 26, 90-95
DOI 10.1016/j.msard.2018.08.032, PubMed 30243235

Kvistad SS, Myhr KM, Holmøy T, Benth JŠ, Wergeland S, Beiske AG, Bjerve KS, Hovdal H, Midgard R, Sagen JV, Torkildsen Ø (2018)
Serum levels of leptin and adiponectin are not associated with disease activity or treatment response in multiple sclerosis
J Neuroimmunol, 323, 73-77
DOI 10.1016/j.jneuroim.2018.07.011, PubMed 30196837

Magelssen M, Holmøy T, Horn MA, Fondenæs OA, Dybwik K, Førde R (2018)
Ethical challenges in tracheostomy-assisted ventilation in amyotrophic lateral sclerosis
J Neurol, 265 (11), 2730-2736
DOI 10.1007/s00415-018-9054-x, PubMed 30218178

Myro AZ, Bjerke G, Zarnovicky S, Holmøy T (2018)
Diffuse alveolar hemorrhage during alemtuzumab infusion in a patient with multiple sclerosis: a case report
BMC Pharmacol Toxicol, 19 (1), 75
DOI 10.1186/s40360-018-0267-5, PubMed 30454022

Nakken O, Holmoy T (2018)
The right to know amyotrophic lateral sclerosis
Tidsskr. Nor. Laegeforen., 138 (16), 1502

Nakken O, Holmoy T, Sorum L (2018)
Genetic testing in amyotrophic lateral sclerosis
Tidsskr. Nor. Laegeforen., 138 (13), 1251-1255

Nakken O, Holmøy T (2018)
The right not to know about amyotrophic lateral sclerosis
Tidsskr Nor Laegeforen, 138 (16)
DOI 10.4045/tidsskr.18.0734, PubMed 30344326

Nakken O, Lindstrøm JC, Holmøy T (2018)
Sex ratio in multiple sclerosis mortality over 65 years; an age-period-cohort analysis in Norway
J Neurol, 265 (6), 1295-1302
DOI 10.1007/s00415-018-8832-9, PubMed 29564602

Nakken O, Sørum L, Holmøy T (2018)
Genetic testing in amyotrophic lateral sclerosis
Tidsskr Nor Laegeforen, 138 (13)
DOI 10.4045/tidsskr.18.0193, PubMed 30180501

Tomescu-Baciu A, Vartdal F, Holmøy T, Vedeler CA, Lossius A (2018)
G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis
Ann Clin Transl Neurol, 5 (10), 1303-1309
DOI 10.1002/acn3.642, PubMed 30349866

Torkildsen Ø, Holmøy T, Myhr KM (2018)
Severe multiple sclerosis reactivation after gonadotropin treatment
Mult Scler Relat Disord, 22, 38-40
DOI 10.1016/j.msard.2018.02.031, PubMed 29525298

Publications 2017

Al-Chalabi A, Andersen PM, Chandran S, Chio A, Corcia P, Couratier P, Danielsson O, de Carvalho M, Desnuelle C, Grehl T, Grosskreutz J, Holmøy T, Ingre C, Karlsborg M, Kleveland G, Koch JC, Koritnik B, KuzmaKozakiewicz M, Laaksovirta H, Ludolph A, McDermott C, Meyer T, Mitre Ropero B, Mora Pardina J, Nygren I et al. (2017)
July 2017 ENCALS statement on edaravone
Amyotroph Lateral Scler Frontotemporal Degener, 18 (7-8), 471-474
DOI 10.1080/21678421.2017.1369125, PubMed 28975816

Holmøy T, Lindstrøm JC, Eriksen EF, Steffensen LH, Kampman MT (2017)
High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis - a randomized controlled trial
BMC Neurol, 17 (1), 67
DOI 10.1186/s12883-017-0851-0, PubMed 28376767

Holmøy T, Torkildsen Ø (2017)
Re: Familieplanlegging, graviditet og amming ved multippel sklerose
Tidsskr Nor Laegeforen, 137 (4), 259
DOI 10.4045/tidsskr.17.0054, PubMed 28225223

Holmøy T, Torkildsen Ø, Myhr KM (2017)
An update on cladribine for relapsing-remitting multiple sclerosis
Expert Opin Pharmacother, 18 (15), 1627-1635
DOI 10.1080/14656566.2017.1372747, PubMed 28858531

Holmøy T, von der Lippe H, Leegaard TM (2017)
Listeria monocytogenes infection associated with alemtuzumab - - a case for better preventive strategies
BMC Neurol, 17 (1), 65
DOI 10.1186/s12883-017-0848-8, PubMed 28376817

Høglund RA, Lossius A, Johansen JN, Homan J, Benth JŠ, Robins H, Bogen B, Bremel RD, Holmøy T (2017)
In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis
Front Immunol, 8, 1255
DOI 10.3389/fimmu.2017.01255, PubMed 29038659

Lossius A, Tomescu-Baciu A, Holmøy T, Vedeler CA, Røsjø E, Lorentzen ÅR, Casetta I, Vartdal F (2017)
Selective intrathecal enrichment of G1m1-positive B cells in multiple sclerosis
Ann Clin Transl Neurol, 4 (10), 756-761
DOI 10.1002/acn3.451, PubMed 29046884

Nakken O, Lindstrøm JC, Tysnes OB, Holmøy T (2017)
Assessing amyotrophic lateral sclerosis prevalence in Norway from 2009 to 2015 from compulsory nationwide health registers
Amyotroph Lateral Scler Frontotemporal Degener, 19 (3-4), 303-310
DOI 10.1080/21678421.2017.1418004, PubMed 29271248

Publications 2016

Berge T, Leikfoss IS, Brorson IS, Bos SD, Page CM, Gustavsen MW, Bjølgerud A, Holmøy T, Celius EG, Damoiseaux J, Smolders J, Harbo HF, Spurkland A (2016)
The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells
Genes Immun, 17 (2), 118-27
DOI 10.1038/gene.2015.61, PubMed 26765264

Bjørnevik K, Riise T, Bostrom I, Casetta I, Cortese M, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Magalhaes S, Pugliatti M, Wolfson C, Myhr KM (2016)
Negative interaction between smoking and EBV in the risk of multiple sclerosis: The EnvIMS study
Mult Scler, 23 (7), 1018-1024
DOI 10.1177/1352458516671028, PubMed 27663872

Holmøy T (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (3), 204-5
DOI 10.4045/tidsskr.16.0051, PubMed 26860374

Holmøy T, Beiske AG, Zarnovicky S, Myro AZ, Røsjø E, Kerty E (2016)
Severe inflammatory disease activity 14 months after cessation of Natalizumab in a patient with Leber's optic neuropathy and multiple sclerosis - a case report
BMC Neurol, 16 (1), 197
DOI 10.1186/s12883-016-0720-2, PubMed 27756254

Holmøy T, Torkildsen Ø (2016)
Can vitamin D reduce inflammation in relapsing-remitting multiple sclerosis?
Expert Rev Neurother, 16 (3), 233-5
DOI 10.1586/14737175.2016.1146134, PubMed 26796244

Holmøy T, Torkildsen Ø (2016)
Family planning, pregnancy and breastfeeding in multiple sclerosis
Tidsskr Nor Laegeforen, 136 (20), 1726-1729
DOI 10.4045/tidsskr.16.0563, PubMed 27830907

Kvistad S, Myhr KM, Holmøy T, Benth JŠ, Løken-Amsrud KI, Wergeland S, Beiske AG, Bjerve KS, Hovdal H, Lilleås F, Midgard R, Pedersen T, Bakke SJ, Torkildsen Ø (2016)
No association of tobacco use and disease activity in multiple sclerosis
Neurol Neuroimmunol Neuroinflamm, 3 (4), e260
DOI 10.1212/NXI.0000000000000260, PubMed 27458599

Lossius A, Johansen JN, Vartdal F, Holmøy T (2016)
High-throughput sequencing of immune repertoires in multiple sclerosis
Ann Clin Transl Neurol, 3 (4), 295-306
DOI 10.1002/acn3.295, PubMed 27081660

Nakken O, Lindstrøm JC, Tysnes OB, Holmøy T (2016)
Mortality trends of amyotrophic lateral sclerosis in Norway 1951-2014: an age-period-cohort study
J Neurol, 263 (12), 2378-2385
DOI 10.1007/s00415-016-8273-2, PubMed 27586392

Nordin A, Akimoto C, Wuolikainen A, Alstermark H, Forsberg K, Baumann P, Pinto S, de Carvalho M, Hübers A, Nordin F, Ludolph AC, Weishaupt JH, Meyer T, Grehl T, Schweikert K, Weber M, Burkhardt C, Neuwirth C, Holmøy T, Morita M, Tysnes OB, Benatar M, Wuu J, Lange DJ, Bisgård C et al. (2016)
Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study
Amyotroph Lateral Scler Frontotemporal Degener, 18 (3-4), 256-264
DOI 10.1080/21678421.2016.1262423, PubMed 27936955

Røsjø E, Lossius A, Abdelmagid N, Lindstrøm JC, Kampman MT, Jørgensen L, Sundström P, Olsson T, Steffensen LH, Torkildsen Ø, Holmøy T (2016)
Effect of high-dose vitamin D3 supplementation on antibody responses against Epstein-Barr virus in relapsing-remitting multiple sclerosis
Mult Scler, 23 (3), 395-402
DOI 10.1177/1352458516654310, PubMed 27325604

Simonsen CS, Celius EG, Brunborg C, Tallaksen C, Eriksen EF, Holmøy T, Moen SM (2016)
Bone mineral density in patients with multiple sclerosis, hereditary ataxia or hereditary spastic paraplegia after at least 10 years of disease - a case control study
BMC Neurol, 16 (1), 252
DOI 10.1186/s12883-016-0771-4, PubMed 27919248

Wergeland S, Myhr KM, Løken-Amsrud KI, Beiske AG, Bjerve KS, Hovdal H, Midgard R, Kvistad SS, Holmøy T, Riise T, Torkildsen Ø (2016)
Vitamin D, HLA-DRB1 and Epstein-Barr virus antibody levels in a prospective cohort of multiple sclerosis patients
Eur J Neurol, 23 (6), 1064-70
DOI 10.1111/ene.12986, PubMed 26998820

Publications 2015

Beiske GA, Holmøy T, Beiske AG, Johannessen SI, Johannessen Landmark C (2015)
Antiepileptic and Antidepressive Polypharmacy in Patients with Multiple Sclerosis
Mult Scler Int, 2015, 317859
DOI 10.1155/2015/317859, PubMed 26221541

Bjørnevik K, Riise T, Cortese M, Holmøy T, Kampman MT, Magalhaes S, Myhr KM, Wolfson C, Pugliatti M (2015)
Level of education and multiple sclerosis risk after adjustment for known risk factors: The EnvIMS study
Mult Scler, 22 (1), 104-11
DOI 10.1177/1352458515579444, PubMed 26014605

Cortese M, Riise T, Bjørnevik K, Holmøy T, Kampman MT, Magalhaes S, Pugliatti M, Wolfson C, Myhr KM (2015)
Timing of use of cod liver oil, a vitamin D source, and multiple sclerosis risk: The EnvIMS study
Mult Scler, 21 (14), 1856-64
DOI 10.1177/1352458515578770, PubMed 25948625

Helland CB, Holmøy T, Gulbrandsen P (2015)
Barriers and Facilitators Related to Rehabilitation Stays in Multiple Sclerosis: A Qualitative Study
Int J MS Care, 17 (3), 122-9
DOI 10.7224/1537-2073.2014-007, PubMed 26052257

Holmøy T, Esbensen QY, Torkildsen Ø, Wergeland S, Bjerve KS, Beiske AG, Midgard R, Šaltytė-Benth J, Hovdal H, Myhr KM (2015)
WT1 and interferon-β-vitamin D association in MS: a longitudinal study
Acta Neurol Scand, 133 (4), 309-12
DOI 10.1111/ane.12448, PubMed 26037530

Johansen JN, Vartdal F, Desmarais C, Tutturen AE, de Souza GA, Lossius A, Holmøy T (2015)
Intrathecal BCR transcriptome in multiple sclerosis versus other neuroinflammation: Equally diverse and compartmentalized, but more mutated, biased and overlapping with the proteome
Clin Immunol, 160 (2), 211-25
DOI 10.1016/j.clim.2015.06.001, PubMed 26055752

Kvistad SS, Myhr KM, Holmøy T, Šaltytė Benth J, Wergeland S, Beiske AG, Bjerve KS, Hovdal H, Lilleås F, Midgard R, Pedersen T, Bakke SJ, Michelsen AE, Aukrust P, Ueland T, Sagen JV, Torkildsen Ø (2015)
Body mass index influence interferon-beta treatment response in multiple sclerosis
J Neuroimmunol, 288, 92-7
DOI 10.1016/j.jneuroim.2015.09.008, PubMed 26531700

Lerum SV, Solbraekke KN, Holmøy T, Frich JC (2015)
Unstable terminality: negotiating the meaning of chronicity and terminality in motor neurone disease
Sociol Health Illn, 37 (1), 81-96
DOI 10.1111/1467-9566.12182, PubMed 25601066

Løken-Amsrud KI, Lossius A, Torkildsen Ø, Holmøy T (2015)
Impact of the environment on multiple sclerosis
Tidsskr Nor Laegeforen, 135 (9), 856-60
DOI 10.4045/tidsskr.14.0751, PubMed 25991624

Magalhaes S, Pugliatti M, Casetta I, Drulovic J, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Lauer K, Myhr KM, Parpinel M, Pekmezovic T, Riise T, Wolfson D, Zhu B, Wolfson C (2015)
The EnvIMS Study: Design and Methodology of an International Case-Control Study of Environmental Risk Factors in Multiple Sclerosis
Neuroepidemiology, 44 (3), 173-81
DOI 10.1159/000381779, PubMed 25967369

Røsjø E, Myhr KM, Løken-Amsrud KI, Bakke SJ, Beiske AG, Bjerve KS, Hovdal H, Lilleås F, Midgard R, Pedersen T, Šaltytė Benth J, Torkildsen Ø, Wergeland S, Michelsen AE, Aukrust P, Ueland T, Holmøy T (2015)
Vitamin D status and effect of interferon-β1a treatment on MRI activity and serum inflammation markers in relapsing-remitting multiple sclerosis
J Neuroimmunol, 280, 21-8
DOI 10.1016/j.jneuroim.2015.02.001, PubMed 25773151

Røsjø E, Steffensen LH, Jørgensen L, Lindstrøm JC, Šaltytė Benth J, Michelsen AE, Aukrust P, Ueland T, Kampman MT, Torkildsen Ø, Holmøy T (2015)
Vitamin D supplementation and systemic inflammation in relapsing-remitting multiple sclerosis
J Neurol, 262 (12), 2713-21
DOI 10.1007/s00415-015-7902-5, PubMed 26429571

Publications 2014

Aspli KT, Flaten TP, Roos PM, Holmøy T, Skogholt JH, Aaseth J (2014)
Iron and copper in progressive demyelination--New lessons from Skogholt's disease
J Trace Elem Med Biol, 31, 183-7
DOI 10.1016/j.jtemb.2014.12.002, PubMed 25563774

Bjørnevik K, Riise T, Casetta I, Drulovic J, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Lauer K, Lossius A, Magalhaes S, Myhr KM, Pekmezovic T, Wesnes K, Wolfson C, Pugliatti M (2014)
Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study
Mult Scler, 20 (8), 1042-9
DOI 10.1177/1352458513513968, PubMed 24414538

Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, Holmoy T, Misu T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV (2014)
The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model
Exp Neurol, 265, 8-21
DOI 10.1016/j.expneurol.2014.12.015, PubMed 25542977

Gulbrandsen P, Ofstad EH, Holmøy T, Vandvik PO (2014)
Shared decision-making in decisions on treatment
Tidsskr Nor Laegeforen, 134 (17), 1670-2
DOI 10.4045/tidsskr.14.0239, PubMed 25223676

Holmøy T, Løken-Amsrud K, Kampman MT, Torkildsen Ø, Myhr KM (2014)
[Re: Vitamin D--how much is enough, and is more better for your health?]
Tidsskr Nor Laegeforen, 134 (10), 1024-5
DOI 10.4045/tidsskr.14.0618, PubMed 24865723

Holmøy T, Myhr KM, Bø L (2014)
[Re: Unethical of neurologists not to offer patients with multiple sclerosis chemotherapy with autologous stem cell support]
Tidsskr Nor Laegeforen, 134 (23-24), 2239-40
DOI 10.4045/tidsskr.14.1458, PubMed 25492327

Kvistad S, Myhr KM, Holmøy T, Bakke S, Beiske AG, Bjerve KS, Hovdal H, Løken-Amsrud KI, Lilleås F, Midgard R, Njølstad G, Pedersen T, Benth JŠ, Wergeland S, Torkildsen O (2014)
Antibodies to Epstein-Barr virus and MRI disease activity in multiple sclerosis
Mult Scler, 20 (14), 1833-40
DOI 10.1177/1352458514533843, PubMed 24842958

Lossius A, Johansen JN, Vartdal F, Robins H, Jūratė Šaltytė B, Holmøy T, Olweus J (2014)
High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells
Eur J Immunol, 44 (11), 3439-52
DOI 10.1002/eji.201444662, PubMed 25103993

McKenna MJ, Holmøy T (2014)
Approach to bone protection in multiple sclerosis
Eur J Neurol, 22 (4), 601-2
DOI 10.1111/ene.12504, PubMed 24986035

Røsjø E, Myhr KM, Løken-Amsrud KI, Bakke SJ, Beiske AG, Bjerve KS, Hovdal H, Lilleås F, Midgard R, Pedersen T, Benth JS, Torkildsen Ø, Wergeland S, Michelsen AE, Aukrust P, Ueland T, Holmøy T (2014)
Increasing serum levels of vitamin A, D and E are associated with alterations of different inflammation markers in patients with multiple sclerosis
J Neuroimmunol, 271 (1-2), 60-5
DOI 10.1016/j.jneuroim.2014.03.014, PubMed 24713402

Torkildsen O, Aarseth J, Benjaminsen E, Celius E, Holmøy T, Kampman MT, Løken-Amsrud K, Midgard R, Myhr KM, Riise T, Grytten N (2014)
Month of birth and risk of multiple sclerosis: confounding and adjustments
Ann Clin Transl Neurol, 1 (2), 141-4
DOI 10.1002/acn3.37, PubMed 25356394

Torkildsen O, Aarseth J, Celius EG, Holmøy T, Kampman MT, Løken-Amsrud KI, Midgard R, Myhr KM, Riise T, Grytten N (2014)
Reply to comment: Month of birth and risk of multiple sclerosis: confounding and adjustments
Ann Clin Transl Neurol, 1 (5), 376-7
DOI 10.1002/acn3.56, PubMed 25356407

Vego H, Sand KL, Høglund RA, Fallang LE, Gundersen G, Holmøy T, Maghazachi AA (2014)
Monomethyl fumarate augments NK cell lysis of tumor cells through degranulation and the upregulation of NKp46 and CD107a
Cell Mol Immunol, 13 (1), 57-64
DOI 10.1038/cmi.2014.114, PubMed 25435072

Wesnes K, Riise T, Casetta I, Drulovic J, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Lauer K, Lossius A, Magalhaes S, Pekmezovic T, Bjørnevik K, Wolfson C, Pugliatti M, Myhr KM (2014)
Body size and the risk of multiple sclerosis in Norway and Italy: the EnvIMS study
Mult Scler, 21 (4), 388-95
DOI 10.1177/1352458514546785, PubMed 25182290

Publications 2013

Holmøy T, Løken-Amsrud KI, Bakke SJ, Beiske AG, Bjerve KS, Hovdal H, Lilleås F, Midgard R, Pedersen T, Saltytė Benth J, Torkildsen O, Wergeland S, Myhr KM, Michelsen AE, Aukrust P, Ueland T (2013)
Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity
PLoS One, 8 (9), e75021
DOI 10.1371/journal.pone.0075021, PubMed 24069377

Høglund RA, Holmøy T, Harbo HF, Maghazachi AA (2013)
A one year follow-up study of natural killer and dendritic cells activities in multiple sclerosis patients receiving glatiramer acetate (GA)
PLoS One, 8 (4), e62237
DOI 10.1371/journal.pone.0062237, PubMed 23614042

Kampman MT, Aarseth JH, Grytten N, Benjaminsen E, Celius EG, Dahl OP, Holmøy T, Løken-Amsrud K, Midgard R, Myhr KM, Risberg G, Vatne A, Torkildsen O (2013)
Sex ratio of multiple sclerosis in persons born from 1930 to 1979 and its relation to latitude in Norway
J Neurol, 260 (6), 1481-8
DOI 10.1007/s00415-012-6814-x, PubMed 23292231

Lossius A, Riise T, Pugliatti M, Bjørnevik K, Casetta I, Drulovic J, Granieri E, Kampman MT, Landtblom AM, Lauer K, Magalhaes S, Myhr KM, Pekmezovic T, Wesnes K, Wolfson C, Holmøy T (2013)
Season of infectious mononucleosis and risk of multiple sclerosis at different latitudes; the EnvIMS Study
Mult Scler, 20 (6), 669-74
DOI 10.1177/1352458513505693, PubMed 24072723

Løken-Amsrud KI, Myhr KM, Bakke SJ, Beiske AG, Bjerve KS, Bjørnarå BT, Hovdal H, Lilleås F, Midgard R, Pedersen T, Benth JŠ, Torkildsen Ø, Wergeland S, Holmøy T (2013)
Alpha-tocopherol and MRI outcomes in multiple sclerosis--association and prediction
PLoS One, 8 (1), e54417
DOI 10.1371/journal.pone.0054417, PubMed 23349882

Torkildsen Ø, Løken-Amsrud KI, Wergeland S, Myhr KM, Holmøy T (2013)
Fat-soluble vitamins as disease modulators in multiple sclerosis
Acta Neurol Scand Suppl (196), 16-23
DOI 10.1111/ane.12045, PubMed 23190287

Publications 2012

Grimaldi L, Barkhof F, Beelke M, Burton J, Holmoy T, Hupperts R, Killestein J, Rieckmann P, Schluep M, Smolders J, SOLAR Study Group (2012)
A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis
Neurology, 78 (11), 841
DOI 10.1212/01.wnl.0000413180.13413.ce, PubMed 22411961

Grytten N, Torkildsen Ø, Aarseth JH, Benjaminsen E, Celius EG, Dahl OP, Holmøy T, Løken-Amsrud K, Midgard R, Myhr KM, Risberg G, Vatne A, Kampman MT (2012)
Month of birth as a latitude-dependent risk factor for multiple sclerosis in Norway
Mult Scler, 19 (8), 1028-34
DOI 10.1177/1352458512471094, PubMed 23257620

Holmøy T, Hanssen KT, Beiske AG (2012)
Patient satisfaction in rehabilitation of patients with multiple sclerosis
Tidsskr Nor Laegeforen, 132 (5), 523-6
DOI 10.4045/tidsskr.11.1043, PubMed 22398768

Holmøy T, Kampman MT, Smolders J (2012)
Vitamin D in multiple sclerosis: implications for assessment and treatment
Expert Rev Neurother, 12 (9), 1101-12
DOI 10.1586/ern.12.99, PubMed 23039389

Holmøy T, Torkildsen Ø, Myhr KM, Løken-Amsrud KI (2012)
Vitamin D supplementation and monitoring in multiple sclerosis: who, when and wherefore
Acta Neurol Scand Suppl (195), 63-9
DOI 10.1111/ane.12028, PubMed 23278659

Lossius A, Johansen JN, Torkildsen Ø, Vartdal F, Holmøy T (2012)
Epstein-Barr virus in systemic lupus erythematosus, rheumatoid arthritis and multiple sclerosis—association and causation
Viruses, 4 (12), 3701-30
DOI 10.3390/v4123701, PubMed 23342374

Løken-Amsrud KI, Holmøy T, Bakke SJ, Beiske AG, Bjerve KS, Bjørnarå BT, Hovdal H, Lilleås F, Midgard R, Pedersen T, Benth JS, Sandvik L, Torkildsen O, Wergeland S, Myhr KM (2012)
Vitamin D and disease activity in multiple sclerosis before and during interferon-β treatment
Neurology, 79 (3), 267-73
DOI 10.1212/WNL.0b013e31825fdf01, PubMed 22700809

Løken-Amsrud KI, Myhr KM, Bakke SJ, Beiske AG, Bjerve KS, Bjørnarå BT, Hovdal H, Lilleås F, Midgard R, Pedersen T, Benth JS, Torkildsen Ø, Wergeland S, Holmøy T (2012)
Retinol levels are associated with magnetic resonance imaging outcomes in multiple sclerosis
Mult Scler, 19 (4), 451-7
DOI 10.1177/1352458512457843, PubMed 22907941

Moen SM, Celius EG, Sandvik L, Brustad M, Nordsletten L, Eriksen EF, Holmøy T (2012)
Bone turnover and metabolism in patients with early multiple sclerosis and prevalent bone mass deficit: a population-based case-control study
PLoS One, 7 (9), e45703
DOI 10.1371/journal.pone.0045703, PubMed 23029191

Pugliatti M, Casetta I, Drulovic J, Granieri E, Holmøy T, Kampman MT, Landtblom AM, Lauer K, Myhr KM, Parpinel M, Pekmezovic T, Riise T, Zhu B, Wolfson C (2012)
A questionnaire for multinational case-control studies of environmental risk factors in multiple sclerosis (EnvIMS-Q)
Acta Neurol Scand Suppl (195), 43-50
DOI 10.1111/ane.12032, PubMed 23278656

Saltytė Benth J, Myhr KM, Løken-Amsrud KI, Beiske AG, Bjerve KS, Hovdal H, Midgard R, Holmøy T (2012)
Modelling and prediction of 25-hydroxyvitamin D levels in Norwegian relapsing-remitting multiple sclerosis patients
Neuroepidemiology, 39 (2), 84-93
DOI 10.1159/000339360, PubMed 22814117

Østern R, Fagerheim T, Ørstavik K, Holmøy T, Heiberg A, Lund-Petersen I, Strom TM, Nilssen Ø, Dahl A (2012)
Hereditary motor neuron disease in a large Norwegian family with a "H46R" substitution in the superoxide dismutase 1 gene
Neuromuscul Disord, 22 (6), 511-21
DOI 10.1016/j.nmd.2012.01.011, PubMed 22475618

Publications 2011

Holmøy T (2011)
[Research on low dosage naltrexone]
Tidsskr Nor Laegeforen, 131 (13-14), 1277-8
DOI 10.4045/tidsskr.11.0578, PubMed 21725378

Holmøy T, Braaten Ø, Hovden IA, Tallaksen CM (2011)
[A young woman with a weakening leg]
Tidsskr Nor Laegeforen, 131 (6), 583-6
DOI 10.4045/tidsskr.09.1499, PubMed 21423311

Holmøy T, Celius EG (2011)
[Development of new therapies for multiple sclerosis]
Tidsskr Nor Laegeforen, 131 (8), 832-6
DOI 10.4045/tidsskr.10.0077, PubMed 21556088

Holmøy T, Lossius A, Gundersen TE, Moen SM, Castellazzi M, Fainardi E, Casetta I (2011)
Intrathecal levels of vitamin D and IgG in multiple sclerosis
Acta Neurol Scand, 125 (6), e28-31
DOI 10.1111/j.1600-0404.2011.01577.x, PubMed 21781056

Kampman MT, Eriksen EF, Holmøy T (2011)
Multiple sclerosis, a cause of secondary osteoporosis? What is the evidence and what are the clinical implications?
Acta Neurol Scand Suppl (191), 44-9
DOI 10.1111/j.1600-0404.2011.01543.x, PubMed 21711256

Lossius A, Vartdal F, Holmøy T (2011)
Vitamin D sensitive EBNA-1 specific T cells in the cerebrospinal fluid of patients with multiple sclerosis
J Neuroimmunol, 240-241, 87-96
DOI 10.1016/j.jneuroim.2011.09.011, PubMed 22018702

Moen SM, Celius EG, Nordsletten L, Holmøy T (2011)
Fractures and falls in patients with newly diagnosed clinically isolated syndrome and multiple sclerosis
Acta Neurol Scand Suppl (191), 79-82
DOI 10.1111/j.1600-0404.2011.01548.x, PubMed 21711261

Moen SM, Celius EG, Sandvik L, Nordsletten L, Eriksen EF, Holmøy T (2011)
Low bone mass in newly diagnosed multiple sclerosis and clinically isolated syndrome
Neurology, 77 (2), 151-7
DOI 10.1212/WNL.0b013e3182242d34, PubMed 21747073

Pandya AD, Al-Jaderi Z, Høglund RA, Holmøy T, Harbo HF, Norgauer J, Maghazachi AA (2011)
Identification of human NK17/NK1 cells
PLoS One, 6 (10), e26780
DOI 10.1371/journal.pone.0026780, PubMed 22039549

Smolders J, Hupperts R, Barkhof F, Grimaldi LM, Holmoy T, Killestein J, Rieckmann P, Schluep M, Vieth R, Hostalek U, Ghazi-Visser L, Beelke M, SOLAR study group (2011)
Efficacy of vitamin D3 as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: a Phase II, multicenter, double-blind, randomized, placebo-controlled trial
J Neurol Sci, 311 (1-2), 44-9
DOI 10.1016/j.jns.2011.04.013, PubMed 21620416

Smolders J, Moen SM, Damoiseaux J, Huitinga I, Holmøy T (2011)
Vitamin D in the healthy and inflamed central nervous system: access and function
J Neurol Sci, 311 (1-2), 37-43
DOI 10.1016/j.jns.2011.07.033, PubMed 21862439

Publications 2010

Holmøy T (2010)
[Autoimmune encephalopathy]
Tidsskr Nor Laegeforen, 130 (10), 1043
DOI 10.4045/tidsskr.10.0323, PubMed 20489808

Holmøy T, Geis C (2010)
The immunological basis for treatment of stiff person syndrome
J Neuroimmunol, 231 (1-2), 55-60
DOI 10.1016/j.jneuroim.2010.09.014, PubMed 20943276

Holmøy T, Harbo HF, Celius EG (2010)
[Treatment of multiple sclerosis]
Tidsskr Nor Laegeforen, 130 (9), 923; author reply 923
DOI 10.4045/tidsskr.10.0346, PubMed 20453948

Holmøy T, Moen SM (2010)
Assessing vitamin D in the central nervous system
Acta Neurol Scand Suppl (190), 88-92
DOI 10.1111/j.1600-0404.2010.01383.x, PubMed 20586743

Holmøy T, Wilson JA, von der Lippe C, Andersen PM, Berg-Hansen P (2010)
G127R: A novel SOD1 mutation associated with rapidly evolving ALS and severe pain syndrome
Amyotroph Lateral Scler, 11 (5), 478-80
DOI 10.3109/17482960903580315, PubMed 20192886

Høglund RA, Hestvik AL, Holmøy T, Maghazachi AA (2010)
Expression and functional activity of chemokine receptors in glatiramer acetate-specific T cells isolated from multiple sclerosis patient receiving the drug glatiramer acetate
Hum Immunol, 72 (2), 124-34
DOI 10.1016/j.humimm.2010.10.016, PubMed 20977917

Publications 2009

Berg-Hansen P, Vandvik B, Fagerhol M, Holmøy T (2009)
Calprotectin levels in the cerebrospinal fluid reflect disease activity in multiple sclerosis
J Neuroimmunol, 216 (1-2), 98-102
DOI 10.1016/j.jneuroim.2009.09.006, PubMed 19800696

Hestvik AL, Skorstad G, Vartdal F, Holmøy T (2009)
Idiotope-specific CD4(+) T cells induce apoptosis of human oligodendrocytes
J Autoimmun, 32 (2), 125-32
DOI 10.1016/j.jaut.2009.01.004, PubMed 19250800

Holmøy T (2009)
[Journalism and ethics]
Tidsskr Nor Laegeforen, 129 (22), 2389
DOI 10.4045/tidsskr.09.1182, PubMed 19935951

Holmøy T (2009)
The discovery of oligoclonal bands: a 50-year anniversary
Eur Neurol, 62 (5), 311-5
DOI 10.1159/000235944, PubMed 19729928

Holmøy T, Førde R (2009)
[The problematic difference]
Tidsskr Nor Laegeforen, 129 (20), 2093
DOI 10.4045/tidsskr.09.0873, PubMed 19855445

Holmøy T, Harbo H, Vartdal F, Spurkland A (2009)
Genetic and molecular approaches to the immunopathogenesis of multiple sclerosis: an update
Curr Mol Med, 9 (5), 591-611
DOI 10.2174/156652409788488793, PubMed 19601809

Holmøy T, Kampman MT (2009)
Alaska, multiple sclerosis, and the vitamin D hypothesis
J Neurol, 257 (2), 305-6
DOI 10.1007/s00415-009-5360-7, PubMed 19862468

Holmøy T, Moen SM, Gundersen TA, Holick MF, Fainardi E, Castellazzi M, Casetta I (2009)
25-hydroxyvitamin D in cerebrospinal fluid during relapse and remission of multiple sclerosis
Mult Scler, 15 (11), 1280-5
DOI 10.1177/1352458509107008, PubMed 19808741

Holmøy T, Skorstad G, Hestvik AL, Alvik KM, Vartdal F (2009)
Protective and detrimental immunity: lessons from stiff person syndrome and multiple sclerosis
Acta Neurol Scand Suppl (189), 22-6
DOI 10.1111/j.1600-0404.2009.01207.x, PubMed 19566493

Holmøy T, Skorstad G, Røste LS, Scheie D, Alvik K (2009)
Stiff person syndrome associated with lower motor neuron disease and infiltration of cytotoxic T cells in the spinal cord
Clin Neurol Neurosurg, 111 (8), 708-12
DOI 10.1016/j.clineuro.2009.06.005, PubMed 19616370

Holmøy T, Vartdal F, Hestvik AL, Munthe L, Bogen B (2009)
The idiotype connection: linking infection and multiple sclerosis
Trends Immunol, 31 (2), 56-62
DOI 10.1016/j.it.2009.11.001, PubMed 19962346

Holmøy T, Aarrestad S, Engstrand P, Ottesen S, Syse A, Førde R (2009)
[Termination of mechanical ventilation in amyotrophic lateral sclerosis]
Tidsskr Nor Laegeforen, 129 (7), 628-31
DOI 10.4045/tidsskr.08.0006, PubMed 19337331

Skorstad G, Vandvik B, Vartdal F, Holmøy T (2009)
MS and clinically isolated syndromes: shared specificity but diverging clonal patterns of virus-specific IgG antibodies produced in vivo and by CSF B cells in vitro
Eur J Neurol, 16 (10), 1124-9
DOI 10.1111/j.1468-1331.2009.02657.x, PubMed 19469834

Publications 2008

Hestvik AL, Skorstad G, Price DA, Vartdal F, Holmoy T (2008)
Multiple sclerosis: glatiramer acetate induces anti-inflammatory T cells in the cerebrospinal fluid
Mult Scler, 14 (6), 749-58
DOI 10.1177/1352458508089411, PubMed 18611988

Holmoy T, Celius EG (2008)
Cost-effectiveness of natalizumab in multiple sclerosis
Expert Rev Pharmacoecon Outcomes Res, 8 (1), 11-21
DOI 10.1586/14737167.8.1.11, PubMed 20528351

Holmøy T (2008)
Medicine and the arts. Pesta on the Stairs by Theodor Kittelsen. Commentary
Acad Med, 83 (1), 74-5
DOI 10.1097/ACM.0b013e31815c65b8, PubMed 18162756

Holmøy T (2008)
T cells in amyotrophic lateral sclerosis
Eur J Neurol, 15 (4), 360-6
DOI 10.1111/j.1468-1331.2008.02065.x, PubMed 18266871

Holmøy T (2008)
The immunology of multiple sclerosis: disease mechanisms and therapeutic targets
Minerva Med, 99 (2), 119-40
PubMed 18431322

Holmøy T, Hestvik AL (2008)
Multiple sclerosis: immunopathogenesis and controversies in defining the cause
Curr Opin Infect Dis, 21 (3), 271-8
DOI 10.1097/QCO.0b013e3282f88b48, PubMed 18448972

Pugliatti M, Harbo HF, Holmøy T, Kampman MT, Myhr KM, Riise T, Wolfson C (2008)
Environmental risk factors in multiple sclerosis
Acta Neurol Scand Suppl, 188, 34-40
DOI 10.1111/j.1600-0404.2008.01029.x, PubMed 18439219

Skorstad G, Hestvik AL, Torjesen P, Alvik K, Vartdal F, Vandvik B, Holmøy T (2008)
GAD65 IgG autoantibodies in stiff person syndrome: clonality, avidity and persistence
Eur J Neurol, 15 (9), 973-80
DOI 10.1111/j.1468-1331.2008.02221.x, PubMed 18637036

Skorstad G, Hestvik AL, Vartdal F, Holmøy T (2008)
Cerebrospinal fluid T cell responses against glutamic acid decarboxylase 65 in patients with stiff person syndrome
J Autoimmun, 32 (1), 24-32
DOI 10.1016/j.jaut.2008.10.002, PubMed 19027267

Publications 2007

Frich JC, Holmoy T (2007)
Rowing without oars [Excerpt] - Commentary
Acad. Med., 82 (6), 595

Frich JC, Holmøy T (2007)
Medicine and the arts. Rowing without Oars [excerpt] by Ulla-Carin Lindquist. Commentary
Acad Med, 82 (6), 594-5
DOI 10.1097/ACM.0b013e31805567d6, PubMed 17525548

Hestvik AL, Vartdal F, Fredriksen AB, Thompson KM, Kvale EO, Skorstad G, Bogen B, Holmoy T (2007)
T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG
Scand J Immunol, 66 (4), 393-401
DOI 10.1111/j.1365-3083.2007.01955.x, PubMed 17850583

Holmøy T (2007)
Immunopathogenesis of multiple sclerosis: concepts and controversies
Acta Neurol Scand Suppl, 187, 39-45
DOI 10.1111/j.1600-0404.2007.00845.x, PubMed 17419827

Holmøy T (2007)
[Knowledge, association capacity and drowsiness]
Tidsskr Nor Laegeforen, 127 (23), 3088
PubMed 18098377

Holmøy T (2007)
Vitamin D status modulates the immune response to Epstein Barr virus: Synergistic effect of risk factors in multiple sclerosis
Med Hypotheses, 70 (1), 66-9
DOI 10.1016/j.mehy.2007.04.030, PubMed 17574770

Holmøy T (2007)
Long-term effect of gabapentin in stiff limb syndrome: a case report
Eur Neurol, 58 (4), 251-2
DOI 10.1159/000107973, PubMed 17851249

Holmøy T, Bjørgo K, Roos PM (2007)
Slowly progressing amyotrophic lateral sclerosis caused by H46R SOD1 mutation
Eur Neurol, 58 (1), 57-8
DOI 10.1159/000102170, PubMed 17483589

Holmøy T, Celius EG (2007)
[Incorrect information about treatment of multiple sclerosis from the Knowledge Center]
Tidsskr Nor Laegeforen, 127 (12), 1672-3; author reply 1673
PubMed 17571115

Holmøy T, Celius EG (2007)
[A rush job and knowledge handling]
Tidsskr Nor Laegeforen, 127 (15), 1961-2
PubMed 17700745

Holmøy T, Horn MA, Vandvik B (2007)
[A stiff-legged man with a bizarre gait]
Tidsskr Nor Laegeforen, 127 (11), 1529-30
PubMed 17566229

Holmøy T, Nakstad PH, Fredø HL, Kumar T (2007)
Intravascular large B-cell lymphoma presenting as cerebellar and cerebral infarction
Arch Neurol, 64 (5), 754-5
DOI 10.1001/archneur.64.5.754, PubMed 17502477

Holmøy T, Vartdal F (2007)
The immunological basis for treatment of multiple sclerosis
Scand J Immunol, 66 (4), 374-82
DOI 10.1111/j.1365-3083.2007.01982.x, PubMed 17850581

Smestad C, Sandvik L, Holmoy T, Harbo HF, Celius EG (2007)
Marked differences in prevalence of multiple sclerosis between ethnic groups in Oslo, Norway
J Neurol, 255 (1), 49-55
DOI 10.1007/s00415-007-0659-8, PubMed 18080855

Publications 2006

Holmøy T (2006)
A Norse contribution to the history of neurological diseases
Eur Neurol, 55 (1), 57-8
DOI 10.1159/000091431, PubMed 16479124

Holmøy T, Frich JC (2006)
[Stories about life with amyotrophic lateral sclerosis]
Tidsskr Nor Laegeforen, 126 (24), 3297-9
PubMed 17170792

Holmøy T, Hestvik AL, Vartdal F (2006)
Towards individualised multiple sclerosis treatment
Lancet Neurol, 5 (2), 111-2
DOI 10.1016/S1474-4422(06)70334-9, PubMed 16426986

Holmøy T, Hestvik AL, Vartdal F (2006)
Management of progressive multifocal leukoencephalopathy associated with natalizumab--possibilities and responsibility
Eur J Neurol, 13 (8), e2
DOI 10.1111/j.1468-1331.2006.01555.x, PubMed 16879280

Holmøy T, Philip AA (2006)
Medicine and the arts. Three Elling Solheim poems translated by Alison Arderne Philip. Commentary
Acad Med, 81 (5), 474-5
DOI 10.1097/01.ACM.0000222269.67835.fa, PubMed 16639206

Holmøy T, Roos PM, Kvale EØ (2006)
ALS: cytokine profile in cerebrospinal fluid T-cell clones
Amyotroph Lateral Scler, 7 (3), 183-6
DOI 10.1080/17482960600664730, PubMed 16963408

Holmøy T, Worren T (2006)
[Communication aids in amyotrophic lateral sclerosis]
Tidsskr Nor Laegeforen, 126 (19), 2523-5
PubMed 17028633

Leirvik A, Liverød M, Holmøy T (2006)
[Quality of life of patients with amyotrophic lateral sclerosis]
Tidsskr Nor Laegeforen, 126 (19), 2520-2
PubMed 17028632

Publications 2005

Holmøy T, Fredriksen AB, Thompson KM, Hestvik AL, Bogen B, Vartdal F (2005)
Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells
Eur J Immunol, 35 (6), 1786-94
DOI 10.1002/eji.200425417, PubMed 15864781

Holmøy T, Vartdal F (2005)
Infectious causes of multiple sclerosis
Lancet Neurol, 4 (5), 268; discussion 269
DOI 10.1016/S1474-4422(05)70054-5, PubMed 15847838

Publications 2004

Holmøy T, Kvale EØ, Vartdal F (2004)
Cerebrospinal fluid CD4+ T cells from a multiple sclerosis patient cross-recognize Epstein-Barr virus and myelin basic protein
J Neurovirol, 10 (5), 278-83
DOI 10.1080/13550280490499524, PubMed 15385250

Holmøy T, Vartdal F (2004)
Cerebrospinal fluid T cells from multiple sclerosis patients recognize autologous Epstein-Barr virus-transformed B cells
J Neurovirol, 10 (1), 52-6
DOI 10.1080/13550280490261671, PubMed 14982728

Publications 2003

Holmøy T, Vandvik B, Vartdal F (2003)
T cells from multiple sclerosis patients recognize immunoglobulin G from cerebrospinal fluid
Mult Scler, 9 (3), 228-34
DOI 10.1191/1352458503ms906oa, PubMed 12814167

Publications 1999

Holmøy T, Berg-Johnsen J, Magnaes B (1999)
[Early postoperative complications in carotid surgery]
Tidsskr Nor Laegeforen, 119 (7), 922-4
PubMed 10210950

Publications 1996

Holmøy T, Sandberg L (1996)
[Painless femoral neck fracture in a patient with multiple sclerosis]
Tidsskr Nor Laegeforen, 116 (2), 249
PubMed 8633335

Publications 1994

Solberg AG, Holmøy T (1994)
[Information--most of the patients are satisfied]
Tidsskr Nor Laegeforen, 114 (8), 988
PubMed 8191481

Publications 1993

Holmøy T (1993)
[Cerebellar infarctions]
Tidsskr Nor Laegeforen, 113 (20), 2564-5
PubMed 8236175

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