Therapeutic drug monitoring of TNFinhibitors and other therapeutic antibodies.
Develop assays for novel immunotherapy drugs such as pembrolizumab, nivolumab and ipilimumab for monitoring drug levels in patients with lung cancer and malignant melanoma.
Develop assays for measuring rituximab and anti-rituximab for monitoring drug level and anti-drug antibody formation.
Detection of antibodies to transglutaminase in the HUNT4-cohort using an in-house dual label assay in collaborative study “Coeliac disease in HUNT”.
Screening for patient antibodies to HH1, a novel antibody-based drug used in lymphoma clinical trials (Lymrit).
Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S(2024) Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16 J Immunother Cancer, 12(4) DOI 10.1136/jitc-2023-008179, PubMed 38604812
Wiken TH, Høivik ML, Anisdahl K, Buer L, Warren DJ, Bolstad N, Hagen M, Moum BA, Medhus AW(2024) Subcutaneous Vedolizumab Treatment in a Real-World Inflammatory Bowel Disease Cohort Switched From Intravenous Vedolizumab: Eighteen-Month Prospective Follow-up Study Crohns Colitis 360, 6(1), otae013 DOI 10.1093/crocol/otae013, PubMed 38544907
Huynh TM, Falk RS, Hellebust TP, Dale E, Astrup GL, Hjermstad MJ, Malinen E, Bjordal K, Kiserud CE, Herlofson BB, Nome R, Amdal CD(2024) Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy Radiother Oncol, 195, 110231(in press) DOI 10.1016/j.radonc.2024.110231, PubMed 38518958