Luka Mesin

  • Research Fellow

More information: visit the Sollid group home page

 

Publications 2019

Esterházy D, Canesso MCC, Mesin L, Muller PA, de Castro TBR, Lockhart A, ElJalby M, Faria AMC, Mucida D (2019)
Compartmentalized gut lymph node drainage dictates adaptive immune responses
Nature, 569 (7754), 126-130
DOI 10.1038/s41586-019-1125-3, PubMed 30988509

Roco JA, Mesin L, Binder SC, Nefzger C, Gonzalez-Figueroa P, Canete PF, Ellyard J, Shen Q, Robert PA, Cappello J, Vohra H, Zhang Y, Nowosad CR, Schiepers A, Corcoran LM, Toellner KM, Polo JM, Meyer-Hermann M, Victora GD, Vinuesa CG (2019)
Class-Switch Recombination Occurs Infrequently in Germinal Centers
Immunity (in press)
DOI 10.1016/j.immuni.2019.07.001, PubMed 31375460

Publications 2018

DeWitt WS, Mesin L, Victora GD, Minin VN, Matsen FA (2018)
Using Genotype Abundance to Improve Phylogenetic Inference
Mol Biol Evol, 35 (5), 1253-1265
DOI 10.1093/molbev/msy020, PubMed 29474671

Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD (2018)
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation
J Exp Med, 215 (10), 2686-2695
DOI 10.1084/jem.20172064, PubMed 30181412

Meyer-Hermann M, Binder SC, Mesin L, Victora GD (2018)
Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers
Front Immunol, 9, 2020
DOI 10.3389/fimmu.2018.02020, PubMed 30319600

Publications 2017

Amitai A, Mesin L, Victora GD, Kardar M, Chakraborty AK (2017)
A Population Dynamics Model for Clonal Diversity in a Germinal Center
Front Microbiol, 8, 1693
DOI 10.3389/fmicb.2017.01693, PubMed 28955307

Bialas AR, Presumey J, Das A, van der Poel CE, Lapchak PH, Mesin L, Victora G, Tsokos GC, Mawrin C, Herbst R, Carroll MC (2017)
Microglia-dependent synapse loss in type I interferon-mediated lupus
Nature, 546 (7659), 539-543
DOI 10.1038/nature22821, PubMed 28614301

Degn SE, van der Poel CE, Firl DJ, Ayoglu B, Al Qureshah FA, Bajic G, Mesin L, Reynaud CA, Weill JC, Utz PJ, Victora GD, Carroll MC (2017)
Clonal Evolution of Autoreactive Germinal Centers
Cell, 170 (5), 913-926.e19
DOI 10.1016/j.cell.2017.07.026, PubMed 28841417

Ersching J, Efeyan A, Mesin L, Jacobsen JT, Pasqual G, Grabiner BC, Dominguez-Sola D, Sabatini DM, Victora GD (2017)
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
Immunity, 46 (6), 1045-1058.e6
DOI 10.1016/j.immuni.2017.06.005, PubMed 28636954

Publications 2016

Bilate AM, Bousbaine D, Mesin L, Agudelo M, Leube J, Kratzert A, Dougan SK, Victora GD, Ploegh HL (2016)
Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor
Sci Immunol, 1 (2), eaaf7471
DOI 10.1126/sciimmunol.aaf7471, PubMed 28783695

Mesin L, Ersching J, Victora GD (2016)
Germinal Center B Cell Dynamics
Immunity, 45 (3), 471-482
DOI 10.1016/j.immuni.2016.09.001, PubMed 27653600

Tas JM, Mesin L, Pasqual G, Targ S, Jacobsen JT, Mano YM, Chen CS, Weill JC, Reynaud CA, Browne EP, Meyer-Hermann M, Victora GD (2016)
Visualizing antibody affinity maturation in germinal centers
Science, 351 (6277), 1048-54
DOI 10.1126/science.aad3439, PubMed 26912368

Publications 2015

Snir O, Mesin L, Gidoni M, Lundin KE, Yaari G, Sollid LM (2015)
Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
J Immunol, 194 (12), 5703-12
DOI 10.4049/jimmunol.1402611, PubMed 25972486

Publications 2014

Steinsbø Ø, Henry Dunand CJ, Huang M, Mesin L, Salgado-Ferrer M, Lundin KE, Jahnsen J, Wilson PC, Sollid LM (2014)
Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
Nat Commun, 5, 4041
DOI 10.1038/ncomms5041, PubMed 24909383

Victora GD, Mesin L (2014)
Clonal and cellular dynamics in germinal centers
Curr Opin Immunol, 28, 90-6
DOI 10.1016/j.coi.2014.02.010, PubMed 24681449

Publications 2012

Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, Lee JH, Huang M, Iversen R, du Pré MF, Qiao SW, Lundin KE, Wilson PC, Sollid LM (2012)
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952

Mesin L, Sollid LM, Di Niro R (2012)
The intestinal B-cell response in celiac disease
Front Immunol, 3, 313
DOI 10.3389/fimmu.2012.00313, PubMed 23060888

Publications 2011

Mesin L, Di Niro R, Thompson KM, Lundin KE, Sollid LM (2011)
Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro
J Immunol, 187 (6), 2867-74
DOI 10.4049/jimmunol.1003181, PubMed 21841131

Publications 2010

Di Niro R, Mesin L, Raki M, Zheng NY, Lund-Johansen F, Lundin KE, Charpilienne A, Poncet D, Wilson PC, Sollid LM (2010)
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
J Immunol, 185 (9), 5377-83
DOI 10.4049/jimmunol.1001587, PubMed 20935207

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