Publications 2021
Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells
J Exp Med, 218 (4)
DOI 10.1084/jem.20201699, PubMed 33332554
Publications 2020
Retraction Note: Microglia-dependent synapse loss in type I interferon-mediated lupus
Nature, 578 (7793), 177
DOI 10.1038/s41586-020-1949-x, PubMed 32025017
T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes
Immunity, 53 (5), 1001-1014.e20
DOI 10.1016/j.immuni.2020.09.003, PubMed 33022229
Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development
PLoS One, 15 (8), e0237773
DOI 10.1371/journal.pone.0237773, PubMed 32822378
Tunable dynamics of B cell selection in gut germinal centres
Nature, 588 (7837), 321-326
DOI 10.1038/nature09385, PubMed 33116306
Publications 2019
Compartmentalized gut lymph node drainage dictates adaptive immune responses
Nature, 569 (7754), 126-130
DOI 10.1038/s41586-019-1125-3, PubMed 30988509
Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting
Cell, 180 (1), 92-106.e11
DOI 10.1016/j.cell.2019.11.032, PubMed 31866068
Class-Switch Recombination Occurs Infrequently in Germinal Centers
Immunity, 51 (2), 337-350.e7
DOI 10.1016/j.immuni.2019.07.001, PubMed 31375460
Publications 2018
Using Genotype Abundance to Improve Phylogenetic Inference
Mol Biol Evol, 35 (5), 1253-1265
DOI 10.1093/molbev/msy020, PubMed 29474671
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation
J Exp Med, 215 (10), 2686-2695
DOI 10.1084/jem.20172064, PubMed 30181412
Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers
Front Immunol, 9, 2020
DOI 10.3389/fimmu.2018.02020, PubMed 30319600
Publications 2017
A Population Dynamics Model for Clonal Diversity in a Germinal Center
Front Microbiol, 8, 1693
DOI 10.3389/fmicb.2017.01693, PubMed 28955307
Microglia-dependent synapse loss in type I interferon-mediated lupus
Nature, 546 (7659), 539-543 (Retracted)
DOI 10.1038/nature22821, PubMed 28614301
Clonal Evolution of Autoreactive Germinal Centers
Cell, 170 (5), 913-926.e19
DOI 10.1016/j.cell.2017.07.026, PubMed 28841417
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
Immunity, 46 (6), 1045-1058.e6
DOI 10.1016/j.immuni.2017.06.005, PubMed 28636954
Publications 2016
Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor
Sci Immunol, 1 (2), eaaf7471
DOI 10.1126/sciimmunol.aaf7471, PubMed 28783695
Germinal Center B Cell Dynamics
Immunity, 45 (3), 471-482
DOI 10.1016/j.immuni.2016.09.001, PubMed 27653600
Visualizing antibody affinity maturation in germinal centers
Science, 351 (6277), 1048-54
DOI 10.1126/science.aad3439, PubMed 26912368
Publications 2015
Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing
J Immunol, 194 (12), 5703-12
DOI 10.4049/jimmunol.1402611, PubMed 25972486
Publications 2014
Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells
Nat Commun, 5, 4041
DOI 10.1038/ncomms5041, PubMed 24909383
Clonal and cellular dynamics in germinal centers
Curr Opin Immunol, 28, 90-6
DOI 10.1016/j.coi.2014.02.010, PubMed 24681449
Publications 2012
High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat Med, 18 (3), 441-5
DOI 10.1038/nm.2656, PubMed 22366952
The intestinal B-cell response in celiac disease
Front Immunol, 3, 313
DOI 10.3389/fimmu.2012.00313, PubMed 23060888
Publications 2011
Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro
J Immunol, 187 (6), 2867-74
DOI 10.4049/jimmunol.1003181, PubMed 21841131
Publications 2010
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
J Immunol, 185 (9), 5377-83
DOI 10.4049/jimmunol.1001587, PubMed 20935207