Publications published since 1976 by Einar K. Rofstad
291 publications found
Publications 2021
-
Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI
Front Oncol, 11, 668916
DOI 10.3389/fonc.2021.668916, PubMed 34094964 -
Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods
Front Oncol, 11, 722773
DOI 10.3389/fonc.2021.722773, PubMed 34621674 -
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
DOI 10.1007/s00259-021-05243-0, PubMed 33606081 -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
J Theor Biol, 526, 110787
DOI 10.1016/j.jtbi.2021.110787, PubMed 34087266
Publications 2020
-
DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness
Cancers (Basel), 12 (7)
DOI 10.3390/cancers12071979, PubMed 32698525 -
Antifibrotic therapy to normalize the tumor microenvironment
J Transl Med, 18 (1), 207
DOI 10.1186/s12967-020-02376-y, PubMed 32434573 -
DCE-MRI of locally-advanced carcinoma of the uterine cervix: Tofts analysis versus non-model-based analyses
Radiat Oncol, 15 (1), 79
DOI 10.1186/s13014-020-01526-2, PubMed 32293487 -
Bevacizumab treatment of meningeal melanoma metastases
J Transl Med, 18 (1), 13
DOI 10.1186/s12967-020-02212-3, PubMed 31915016
Publications 2019
-
Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts
Front Oncol, 9, 845
DOI 10.3389/fonc.2019.00845, PubMed 31555596 -
Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts
Transl Oncol, 12 (8), 1079-1085
DOI 10.1016/j.tranon.2019.05.012, PubMed 31174058 -
DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 104 (3), 666-676
DOI 10.1016/j.ijrobp.2019.03.002, PubMed 30858145 -
Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model
Acta Oncol, 58 (6), 828-837
DOI 10.1080/0284186X.2019.1580386, PubMed 30810443
Publications 2018
-
Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy
Transl Oncol, 11 (5), 1128-1136
DOI 10.1016/j.tranon.2018.07.005, PubMed 30036782 -
Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
J Exp Clin Cancer Res, 37 (1), 92
DOI 10.1186/s13046-018-0763-x, PubMed 29703238 -
DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 102 (4), 1193-1201
DOI 10.1016/j.ijrobp.2018.04.035, PubMed 29859790 -
Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation
Oncotarget, 9 (30), 21036-21051
DOI 10.18632/oncotarget.24783, PubMed 29765518 -
DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts
Neoplasia, 20 (7), 734-744
DOI 10.1016/j.neo.2018.05.006, PubMed 29886124
Publications 2017
-
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget, 8 (29), 48060-48074
DOI 10.18632/oncotarget.18231, PubMed 28624797 -
The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Transl Oncol, 10 (2), 158-167
DOI 10.1016/j.tranon.2016.12.007, PubMed 28167241 -
Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BMC Cancer, 17 (1), 411
DOI 10.1186/s12885-017-3404-4, PubMed 28606060 -
Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
J Transl Med, 15 (1), 241
DOI 10.1186/s12967-017-1347-9, PubMed 29183378 -
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
J Transl Med, 15 (1), 225
DOI 10.1186/s12967-017-1331-4, PubMed 29100521 -
Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer
Oncotarget, 8 (62), 105682-105691
DOI 10.18632/oncotarget.22388, PubMed 29285283 -
Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
J Transl Med, 15 (1), 203
DOI 10.1186/s12967-017-1307-4, PubMed 29017512 -
Cancer stem cells (CSCs), cervical CSCs and targeted therapies
Oncotarget, 8 (21), 35351-35367
DOI 10.18632/oncotarget.10169, PubMed 27343550 -
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Acta Oncol, 56 (5), 675-681
DOI 10.1080/0284186X.2017.1294762, PubMed 28447564 -
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts
Acta Oncol, 56 (12), 1754-1762
DOI 10.1080/0284186X.2017.1343494, PubMed 28661213
Publications 2016
-
Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression
Oncotarget, 7 (47), 76806-76815
DOI 10.18632/oncotarget.12695, PubMed 27756886 -
Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis
Oncotarget, 7 (35), 56986-56997
DOI 10.18632/oncotarget.10931, PubMed 27486768 -
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix
Cancer Lett, 373 (2), 147-55
DOI 10.1016/j.canlet.2016.01.047, PubMed 26828134 -
Intracranial Tumor Cell Migration and the Development of Multiple Brain Metastases in Malignant Melanoma
Transl Oncol, 9 (3), 211-8
DOI 10.1016/j.tranon.2016.04.003, PubMed 27267839 -
Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content
J Transl Med, 14 (1), 161
DOI 10.1186/s12967-016-0920-y, PubMed 27268062
Publications 2015
-
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix
BMC Cancer, 15, 805
DOI 10.1186/s12885-015-1828-2, PubMed 26502718 -
Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging
BMC Cancer, 15, 900
DOI 10.1186/s12885-015-1918-1, PubMed 26573613 -
Identification of Metastasis-Associated Metabolic Profiles of Tumors by (1)H-HR-MAS-MRS
Neoplasia, 17 (10), 767-75
DOI 10.1016/j.neo.2015.10.001, PubMed 26585232 -
Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer
Radiother Oncol, 115 (3), 379-85
DOI 10.1016/j.radonc.2015.05.001, PubMed 25998804 -
Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases
J Exp Clin Cancer Res, 34, 150
DOI 10.1186/s13046-015-0264-0, PubMed 26667022
Publications 2014
-
Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts
Microvasc Res, 98, 159-65
DOI 10.1016/j.mvr.2014.02.005, PubMed 24555949 -
DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts
BMC Cancer, 14, 92
DOI 10.1186/1471-2407-14-92, PubMed 24528854 -
Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
Radiother Oncol, 113 (1), 132-8
DOI 10.1016/j.radonc.2014.09.011, PubMed 25443501 -
Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis
Neoplasia, 16 (7), 586-94
DOI 10.1016/j.neo.2014.07.003, PubMed 25117980
Publications 2013
-
DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts
Radiother Oncol, 110 (2), 335-41
DOI 10.1016/j.radonc.2013.10.018, PubMed 24231244 -
The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI
Transl Oncol, 6 (5), 607-17
DOI 10.1593/tlo.13313, PubMed 24151541 -
Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts
J Exp Clin Cancer Res, 32, 93
DOI 10.1186/1756-9966-32-93, PubMed 24245934 -
The efficacy of CHK1 inhibitors is not altered by hypoxia, but is enhanced after reoxygenation
Mol Cancer Ther, 12 (5), 705-16
DOI 10.1158/1535-7163.MCT-12-0879, PubMed 23635654 -
Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI
Acta Oncol, 53 (1), 6-15
DOI 10.3109/0284186X.2013.773073, PubMed 23445339
Publications 2012
-
Microenvironment-associated lymph node metastasis of human cervical carcinoma xenografts
Acta Oncol, 51 (4), 465-72
DOI 10.3109/0284186X.2011.636751, PubMed 22292610 -
pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (4), 1317-23
DOI 10.1016/j.ijrobp.2011.09.037, PubMed 22270159 -
A novel application of dorsal window chambers: repetitive imaging of tumor-associated lymphatics
Microvasc Res, 83 (3), 360-5
DOI 10.1016/j.mvr.2012.02.003, PubMed 22342351 -
Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts
BMC Cancer, 12, 388
DOI 10.1186/1471-2407-12-388, PubMed 22947392 -
Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply
Microvasc Res, 85, 10-5
DOI 10.1016/j.mvr.2012.11.002, PubMed 23154277 -
Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure
BMC Cancer, 12, 544
DOI 10.1186/1471-2407-12-544, PubMed 23173554 -
Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI
Cancer Res, 72 (19), 4899-908
DOI 10.1158/0008-5472.CAN-12-0903, PubMed 23027087 -
Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights
Acta Oncol, 52 (3), 627-35
DOI 10.3109/0284186X.2012.737931, PubMed 23126523 -
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (1), e121-7
DOI 10.1016/j.ijrobp.2011.12.019, PubMed 22381901 -
High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts
PLoS One, 7 (6), e40006
DOI 10.1371/journal.pone.0040006, PubMed 22768196 -
Vascular abnormalities associated with acute hypoxia in human melanoma xenografts
Radiother Oncol, 105 (1), 72-8
DOI 10.1016/j.radonc.2012.08.018, PubMed 23022175 -
Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts
Microvasc Res, 85, 16-23
DOI 10.1016/j.mvr.2012.11.001, PubMed 23149341 -
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: a preclinical study of cervical carcinoma and melanoma xenografts
Acta Oncol, 52 (3), 604-11
DOI 10.3109/0284186X.2012.689851, PubMed 22671573
Publications 2011
-
Dynamic contrast-enhanced-MRI of tumor hypoxia
Magn Reson Med, 67 (2), 519-30
DOI 10.1002/mrm.23014, PubMed 21661044 -
Interstitial fluid pressure and vascularity of intradermal and intramuscular human tumor xenografts
Int J Radiat Oncol Biol Phys, 80 (1), 258-64
DOI 10.1016/j.ijrobp.2010.11.042, PubMed 21255944 -
Assessment of tumor hypoxia and interstitial fluid pressure by gadomelitol-based dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 101 (1), 217-22
DOI 10.1016/j.radonc.2011.06.036, PubMed 21840612 -
Differentiation between hypoxic and non-hypoxic experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 98 (3), 360-4
DOI 10.1016/j.radonc.2010.12.016, PubMed 21262548 -
Assessment of tumor radioresponsiveness and metastatic potential by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 81 (1), 255-61
DOI 10.1016/j.ijrobp.2011.04.008, PubMed 21816291 -
Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 102 (3), 429-35
DOI 10.1016/j.radonc.2011.11.013, PubMed 22197352
Publications 2010
-
Magnetic resonance imaging of tumor necrosis
Acta Oncol, 50 (3), 427-34
DOI 10.3109/0284186X.2010.526633, PubMed 20950229 -
Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology
Radiother Oncol, 97 (2), 217-24
DOI 10.1016/j.radonc.2010.06.011, PubMed 20656365 -
Interstitial fluid pressure of tumors as a function of parameters derived by dynamic contrast-enhanced magnetic resonance imaging: Response to letter by Farace and Boschi
Radiother. Oncol., 94 (3), 385-386
DOI 10.1016/j.radonc.2009.12.025 -
Quantitative assessment of hypoxia in melanoma xenografts by dynamic contrast-enhanced magnetic resonance imaging: intradermal versus intramuscular tumors
Radiother Oncol, 97 (2), 233-8
DOI 10.1016/j.radonc.2010.09.005, PubMed 20934767 -
Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination
Int J Cancer, 127 (7), 1535-46
DOI 10.1002/ijc.25176, PubMed 20091868 -
Metastasis in melanoma xenografts is associated with tumor microvascular density rather than extent of hypoxia
Neoplasia, 12 (11), 889-98
DOI 10.1593/neo.10712, PubMed 21076614 -
Associations between radiocurability and interstitial fluid pressure in human tumor xenografts without hypoxic tissue
Clin Cancer Res, 16 (3), 936-45
DOI 10.1158/1078-0432.CCR-09-2718, PubMed 20103667 -
Development of hypoxia in a preclinical model of tumor micrometastases
Int J Radiat Oncol Biol Phys, 76 (3), 879-88
DOI 10.1016/j.ijrobp.2009.09.045, PubMed 20159362
Publications 2009
-
Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images
Radiat Res, 172 (3), 339-47
DOI 10.1667/RR1787.1, PubMed 19708783 -
Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 73 (3), 838-45
DOI 10.1016/j.ijrobp.2008.10.062, PubMed 19215820 -
Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors
J Cancer Res Clin Oncol, 135 (9), 1177-84
DOI 10.1007/s00432-009-0558-8, PubMed 19214568 -
Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries
Neoplasia, 11 (3), 277-85
DOI 10.1593/neo.81400, PubMed 19242609 -
Radiocurability is associated with interstitial fluid pressure in human tumor xenografts
Neoplasia, 11 (11), 1243-51
DOI 10.1593/neo.91152, PubMed 19881960
Publications 2008
-
Limitations of dynamic contrast-enhanced MRI in monitoring radiation-induced changes in the fraction of radiobiologically hypoxic cells in human melanoma xenografts
J Magn Reson Imaging, 28 (5), 1209-18
DOI 10.1002/jmri.21602, PubMed 18972344 -
Temporal heterogeneity in blood supply in human tumor xenografts
Neoplasia, 10 (7), 727-35
DOI 10.1593/neo.08388, PubMed 18592011 -
Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI
Radiat Res, 169 (6), 689-99
DOI 10.1667/RR1311.1, PubMed 18494552 -
Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging
Neoplasia, 10 (4), 354-62
DOI 10.1593/neo.08162, PubMed 18392132 -
Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure
Radiother Oncol, 91 (1), 107-13
DOI 10.1016/j.radonc.2008.08.015, PubMed 18973959 -
Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry
Radiat Res, 170 (5), 638-50
DOI 10.1667/RR1400.1, PubMed 18959463 -
Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
Photochem Photobiol, 85 (3), 740-9
DOI 10.1111/j.1751-1097.2008.00477.x, PubMed 19076314
Publications 2007
-
Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling
Magn Reson Imaging, 26 (2), 160-70
DOI 10.1016/j.mri.2007.06.003, PubMed 17692490 -
Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI
Magn Reson Med, 58 (3), 473-81
DOI 10.1002/mrm.21367, PubMed 17763357 -
Dynamic contrast-enhanced magnetic resonance imaging of human melanoma xenografts with necrotic regions
J Magn Reson Imaging, 26 (1), 133-43
DOI 10.1002/jmri.20939, PubMed 17659570 -
Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis
Clin Cancer Res, 13 (7), 1971-8
DOI 10.1158/1078-0432.CCR-06-1967, PubMed 17360973 -
Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI
J Magn Reson Imaging, 26 (4), 1033-42
DOI 10.1002/jmri.21110, PubMed 17896373 -
A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber
Microvasc Res, 75 (2), 179-87
DOI 10.1016/j.mvr.2007.06.009, PubMed 17688890
Publications 2006
-
Fluctuations in pO2 in irradiated human melanoma xenografts
Radiat Res, 165 (1), 16-25
DOI 10.1667/rr3491.1, PubMed 16392958 -
Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI
Magn Reson Med, 55 (4), 874-82
DOI 10.1002/mrm.20852, PubMed 16506163 -
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
Cancer Res, 66 (13), 6699-707
DOI 10.1158/0008-5472.CAN-06-0983, PubMed 16818644
Publications 2005
-
Fluctuations in pO2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy
Radiother Oncol, 77 (2), 220-6
DOI 10.1016/j.radonc.2005.09.009, PubMed 16257074 -
Intratumor heterogeneity in blood perfusion in orthotopic human melanoma xenografts assessed by dynamic contrast-enhanced magnetic resonance imaging
J Magn Reson Imaging, 21 (6), 792-800
DOI 10.1002/jmri.20321, PubMed 15906326 -
Comparison of tumor blood perfusion assessed by dynamic contrast-enhanced MRI with tumor blood supply assessed by invasive imaging
J Magn Reson Imaging, 21 (3), 272-81
DOI 10.1002/jmri.20265, PubMed 15723369 -
Changes in intratumor heterogeneity in blood perfusion in intradermal human melanoma xenografts during tumor growth assessed by DCE-MRI
Magn Reson Imaging, 23 (9), 961-6
DOI 10.1016/j.mri.2005.09.006, PubMed 16310112 -
Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms
Cancer Res, 65 (5), 1877-86
DOI 10.1158/0008-5472.CAN-04-2828, PubMed 15753386 -
The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products
Cancer Res, 65 (6), 2387-96
DOI 10.1158/0008-5472.CAN-04-3039, PubMed 15781654
Publications 2004
-
Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors
Int J Radiat Oncol Biol Phys, 58 (1), 267-77
DOI 10.1016/s0360-3016(03)01613-4, PubMed 14697448 -
Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: a preclinical study of human melanoma xenografts
Magn Reson Med, 52 (2), 269-76
DOI 10.1002/mrm.20149, PubMed 15282808 -
Tumor-line specific pO(2) fluctuations in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 58 (2), 403-9
DOI 10.1016/j.ijrobp.2003.09.049, PubMed 14751509 -
Quantitative assessment of uptake and distribution of iron oxide particles (NC100150) in human melanoma xenografts by contrast-enhanced MRI
Magn Reson Med, 51 (4), 727-35
DOI 10.1002/mrm.20028, PubMed 15065245 -
Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 58 (2), 493-9
DOI 10.1016/j.ijrobp.2003.09.030, PubMed 14751520 -
Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor
Cancer Res, 64 (1), 13-8
DOI 10.1158/0008-5472.can-03-2658, PubMed 14729600
Publications 2003
-
Temporal heterogeneity in oxygen tension in human melanoma xenografts
Br J Cancer, 89 (2), 350-6
DOI 10.1038/sj.bjc.6601047, PubMed 12865929 -
Intratumour heterogeneity in the uptake of macromolecular therapeutic agents in human melanoma xenografts
Br J Cancer, 88 (2), 291-7
DOI 10.1038/sj.bjc.6600680, PubMed 12610516 -
Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts
Cancer Res, 63 (14), 4055-61
PubMed 12874006
Publications 2002
-
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine
Int J Radiat Oncol Biol Phys, 52 (3), 858-68
DOI 10.1016/s0360-3016(01)02734-1, PubMed 11849812 -
N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth
Oncogene, 21 (22), 3552-61
DOI 10.1038/sj.onc.1205440, PubMed 12032857 -
Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8
Br J Cancer, 86 (2), 301-8
DOI 10.1038/sj.bjc.6600052, PubMed 11870523 -
Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor
Cancer Res, 62 (6), 1847-53
PubMed 11912164 -
Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts
Cancer Res, 62 (3), 661-4
PubMed 11830516
Publications 2001
-
Microvascular permeability to macromolecules in human melanoma xenografts assessed by contrast-enhanced MRI--intertumor and intratumor heterogeneity
Magn Reson Imaging, 19 (5), 723-30
DOI 10.1016/s0730-725x(01)00377-0, PubMed 11672631 -
Transvascular and interstitial transport of a 19 kDa linear molecule in human melanoma xenografts measured by contrast-enhanced magnetic resonance imaging
J Magn Reson Imaging, 14 (5), 608-16
DOI 10.1002/jmri.1226, PubMed 11747014 -
Microvascular permeability of human melanoma xenografts to macromolecules: relationships to tumor volumetric growth rate, tumor angiogenesis, and VEGF expression
Microvasc Res, 61 (2), 187-98
DOI 10.1006/mvre.2001.2303, PubMed 11254398 -
Intra- and intertumor heterogeneity in blood perfusion of human cervical cancer before treatment and after radiotherapy
Int J Cancer, 96 (3), 182-90
DOI 10.1002/ijc.1019, PubMed 11410887 -
Assessment of tumor oxygenation in human cervical carcinoma by use of dynamic Gd-DTPA-enhanced MR imaging
J Magn Reson Imaging, 14 (6), 750-6
DOI 10.1002/jmri.10016, PubMed 11747032 -
Microvessel oxyhemoglobin saturation does not reflect tissue oxygen tension in human melanoma xenografts
Microvasc Res, 61 (2), 199-202
DOI 10.1006/mvre.2000.2294, PubMed 11254399 -
Intratumour heterogeneity in microvessel oxyhaemoglobin saturations
Cancer Lett, 162 (2), 245-51
DOI 10.1016/s0304-3835(00)00670-4, PubMed 11146232 -
Thrombospondin-1-mediated metastasis suppression by the primary tumor in human melanoma xenografts
J Invest Dermatol, 117 (5), 1042-9
DOI 10.1046/j.0022-202x.2001.01552.x, PubMed 11710911
Publications 2000
-
Measurement of the extracellular volume of human melanoma xenografts by contrast enhanced magnetic resonance imaging
Magn Reson Imaging, 18 (1), 41-8
DOI 10.1016/s0730-725x(99)00109-5, PubMed 10642101 -
Intratumor heterogeneity in perfusion in human melanoma xenografts measured by contrast-enhanced magnetic resonance imaging
Magn Reson Imaging, 18 (8), 997-1002
DOI 10.1016/s0730-725x(00)00188-0, PubMed 11121704 -
The constitutive level of vascular endothelial growth factor (VEGF) is more important than hypoxia-induced VEGF up-regulation in the angiogenesis of human melanoma xenografts
Br J Cancer, 82 (9), 1528-34
DOI 10.1054/bjoc.2000.1173, PubMed 10789719 -
Macromolecule uptake in human melanoma xenografts. relationships to blood supply, vascular density, microvessel permeability and extracellular volume fraction
Eur J Cancer, 36 (11), 1433-40
DOI 10.1016/s0959-8049(00)00120-9, PubMed 10899658 -
Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging
Magn Reson Med, 43 (6), 828-36
DOI 10.1002/1522-2594(200006)43:6<828::aid-mrm8>3.0.co;2-p, PubMed 10861877 -
Changes in tumor oxygen tension during radiotherapy of uterine cervical cancer: relationships to changes in vascular density, cell density, and frequency of mitosis and apoptosis
Int J Radiat Oncol Biol Phys, 46 (4), 935-46
DOI 10.1016/s0360-3016(99)00497-6, PubMed 10705016 -
Disease control of uterine cervical cancer: relationships to tumor oxygen tension, vascular density, cell density, and frequency of mitosis and apoptosis measured before treatment and during radiotherapy
Clin Cancer Res, 6 (3), 1104-12
PubMed 10741740 -
Mathematical modeling of chronical hypoxia in tumors considering potential doubling time and hypoxic cell lifetime
Radiother Oncol, 54 (2), 171-7
DOI 10.1016/s0167-8140(99)00154-1, PubMed 10699481 -
Microenvironment-induced cancer metastasis
Int J Radiat Biol, 76 (5), 589-605
DOI 10.1080/095530000138259, PubMed 10866281 -
Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
Cancer Res, 60 (17), 4932-8
PubMed 10987309 -
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
Br J Cancer, 83 (3), 354-9
DOI 10.1054/bjoc.2000.1266, PubMed 10917551 -
Treatment outcome in advanced squamous cell carcinoma of the uterine cervix: relationships to pretreatment tumor oxygenation and vascularization
Radiother Oncol, 54 (2), 101-7
DOI 10.1016/s0167-8140(99)00175-9, PubMed 10699471 -
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
Cancer Res, 60 (4), 916-21
PubMed 10706105
Publications 1999
-
No association between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines
Int J Radiat Biol, 75 (9), 1149-60
DOI 10.1080/095530099139629, PubMed 10528923 -
Changes in oxygen tension during radiotherapy of head and neck tumours
Acta Oncol, 38 (8), 1037-42
DOI 10.1080/028418699432329, PubMed 10665759 -
Monitoring of tumor reoxygenation following irradiation by 31P magnetic resonance spectroscopy: an experimental study of human melanoma xenografts
Radiother Oncol, 52 (3), 261-7
DOI 10.1016/s0167-8140(99)00075-4, PubMed 10580874 -
Effects of hyperthermia on bioenergetic status and phosphorus T1S in human melanoma xenografts monitored by 31P-MRS
Magn Reson Imaging, 17 (7), 1049-56
DOI 10.1016/s0730-725x(99)00032-6, PubMed 10463656 -
Measurement of proliferation activity in human melanoma xenografts by magnetic resonance imaging
Magn Reson Imaging, 17 (3), 393-402
DOI 10.1016/s0730-725x(98)00175-1, PubMed 10195582 -
Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis
Br J Cancer, 80 (11), 1697-707
DOI 10.1038/sj.bjc.6690586, PubMed 10468285 -
Radiobiological and immunohistochemical assessment of hypoxia in human melanoma xenografts: acute and chronic hypoxia in individual tumours
Int J Radiat Biol, 75 (11), 1377-93
DOI 10.1080/095530099139250, PubMed 10597912 -
Interstitial fluid pressure and capillary diameter distribution in human melanoma xenografts
Microvasc Res, 58 (3), 205-14
DOI 10.1006/mvre.1999.2184, PubMed 10527764
Publications 1998
-
Hypoxia induces p53 accumulation in the S-phase and accumulation of hypophosphorylated retinoblastoma protein in all cell cycle phases of human melanoma cells
Br J Cancer, 78 (12), 1547-58
DOI 10.1038/bjc.1998.722, PubMed 9862563 -
VEGF, bFGF and EGF in the angiogenesis of human melanoma xenografts
Int J Cancer, 76 (6), 836-41
DOI 10.1002/(sici)1097-0215(19980610)76:6<836::aid-ijc12>3.0.co;2-0, PubMed 9626350 -
Measurement of perfusion rate in human melanoma xenografts by contrast-enhanced magnetic resonance imaging
Magn Reson Med, 40 (1), 89-98
DOI 10.1002/mrm.1910400113, PubMed 9660558 -
Oxygen tension in human squamous cell carcinoma and adenocarcinoma of the uterine cervix
Adv Exp Med Biol, 454, 635-41
DOI 10.1007/978-1-4615-4863-8_75, PubMed 9889944 -
Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma
Br J Cancer, 77 (6), 897-902
DOI 10.1038/bjc.1998.148, PubMed 9528831 -
Fraction of radiobiologically hypoxic cells in human melanoma xenografts measured by using single-cell survival, tumour growth delay and local tumour control as end points
Br J Cancer, 78 (7), 893-8
DOI 10.1038/bjc.1998.598, PubMed 9764580 -
Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix
Br J Cancer, 78 (6), 822-7
DOI 10.1038/bjc.1998.586, PubMed 9743308 -
Oxygen tension and vascular density in adenocarcinoma and squamous cell carcinoma of the uterine cervix
Acta Oncol, 37 (7-8), 665-70
DOI 10.1080/028418698430016, PubMed 10050984 -
Vascular density in human melanoma xenografts: relationship to angiogenesis, perfusion and necrosis
Cancer Lett, 123 (2), 159-65
DOI 10.1016/s0304-3835(97)00424-2, PubMed 9489483 -
Interstitial fluid pressure, fraction of necrotic tumor tissue, and tumor cell density in human melanoma xenografts
Acta Oncol, 37 (3), 291-7
DOI 10.1080/028418698429603, PubMed 9677102
Publications 1997
-
Critical soft tissues of the female pelvis: serial MR imaging before, during, and after radiation therapy
Radiology, 203 (2), 391-7
DOI 10.1148/radiology.203.2.9114093, PubMed 9114093 -
Hypoxia-induced changes in radiation sensitivity in human melanoma cells: importance of oxygen-regulated proteins, adenylate energy charge and cell cycle distribution
Radiother Oncol, 44 (2), 177-82
DOI 10.1016/s0167-8140(97)01929-4, PubMed 9288847 -
Oxygen tension in human tumours measured with polarographic needle electrodes and its relationship to vascular density, necrosis and hypoxia
Radiother Oncol, 44 (2), 163-9
DOI 10.1016/s0167-8140(97)01920-8, PubMed 9288845 -
Oxygen tension in primary tumours of the uterine cervix and lymph node metastases of the head and neck
Adv Exp Med Biol, 428, 55-60
DOI 10.1007/978-1-4615-5399-1_9, PubMed 9500029 -
Proton relaxation times and interstitial fluid pressure in human melanoma xenografts
Br J Cancer, 75 (2), 180-3
DOI 10.1038/bjc.1997.30, PubMed 9010023 -
CCD imaging in cryospectrophotometric determination of microvascular oxyhemoglobin saturations
Am J Physiol, 273 (6), H2910-8
DOI 10.1152/ajpheart.1997.273.6.H2910, PubMed 9435631 -
Radiation-induced changes in phosphorus T1 values in human melanoma xenografts studied by 31P-MRS
Magn Reson Imaging, 15 (10), 1187-92
DOI 10.1016/s0730-725x(97)00181-1, PubMed 9408139 -
Energy metabolism in human melanoma cells under hypoxic and acidic conditions in vitro
Br J Cancer, 76 (4), 421-8
DOI 10.1038/bjc.1997.405, PubMed 9275017 -
Polarographic measurement of pO2 in cervix carcinoma
Gynecol Oncol, 64 (2), 230-6
DOI 10.1006/gyno.1996.4571, PubMed 9038268 -
Correlation of high lactate levels in head and neck tumors with incidence of metastasis
Am J Pathol, 150 (2), 409-15
PubMed 9033256
Publications 1996
-
Incidence of radiation-induced insufficiency fractures of the female pelvis: evaluation with MR imaging
AJR Am J Roentgenol, 167 (5), 1205-10
DOI 10.2214/ajr.167.5.8911181, PubMed 8911181 -
Noncritical soft tissues of the female pelvis: serial MR imaging before, during, and after radiation therapy
Radiology, 199 (2), 461-8
DOI 10.1148/radiology.199.2.8668795, PubMed 8668795 -
Oxygen tension and vascular density in human cervix carcinoma
Br J Cancer, 74 (10), 1559-63
DOI 10.1038/bjc.1996.589, PubMed 8932335 -
Apoptosis, energy metabolism, and fraction of radiobiologically hypoxic cells: a study of human melanoma multicellular spheroids
Int J Radiat Biol, 70 (3), 241-9
DOI 10.1080/095530096144978, PubMed 8800195 -
Hypoxia-induced tetraploidisation of a diploid human melanoma cell line in vitro
Br J Cancer Suppl, 27, S136-9
PubMed 8763866 -
Xenograft model systems for human melanoma
Mol Med Today, 2 (9), 394-403
DOI 10.1016/s1357-4310(96)10035-6, PubMed 8885259 -
Interstitial fluid pressure, perfusion rate and oxygen tension in human melanoma xenografts
Br J Cancer Suppl, 27, S252-5
PubMed 8763891
Publications 1995
-
Female pelvic bone marrow: serial MR imaging before, during, and after radiation therapy
Radiology, 194 (2), 537-43
DOI 10.1148/radiology.194.2.7824737, PubMed 7824737 -
Detection of necrosis in human tumour xenografts by proton magnetic resonance imaging
Br J Cancer, 71 (3), 456-61
DOI 10.1038/bjc.1995.93, PubMed 7880724 -
MRI of human tumor xenografts in vivo: proton relaxation times and extracellular tumor volume
Magn Reson Imaging, 13 (5), 693-700
DOI 10.1016/0730-725x(95)00019-d, PubMed 8569443 -
Growth rates or radiobiological hypoxia are not correlated with local metabolite content in human melanoma xenografts with similar vascular network
Br J Cancer, 72 (4), 912-6
DOI 10.1038/bjc.1995.432, PubMed 7547239 -
31P NMR spectroscopy studies of phospholipid metabolism in human melanoma xenograft lines differing in rate of tumour cell proliferation
NMR Biomed, 8 (2), 65-71
DOI 10.1002/nbm.1940080204, PubMed 7547188 -
Treatment failure following sequential thermoradiotherapy of locally advanced breast carcinoma occurs primarily in poorly vascularized tumors
Oncology, 52 (6), 443-7
DOI 10.1159/000227508, PubMed 7478428 -
Spin-lattice relaxation time of inorganic phosphate in human tumor xenografts measured in vivo by 31P-magnetic resonance spectroscopy. Influence of oxygen tension
Acta Oncol, 34 (3), 339-43
DOI 10.3109/02841869509093986, PubMed 7779420 -
Effect of melanin on phosphorus T1S in human melanoma xenografts studied by 31P MRS
Magn Reson Imaging, 13 (6), 847-52
DOI 10.1016/0730-725x(95)00054-k, PubMed 8544656 -
Metastatic behavior of human tumors in congenitally athymic nude mice: intrinsic properties of the tumor cells and host immune reactivity
Int J Cancer, 63 (5), 744-9
DOI 10.1002/ijc.2910630523, PubMed 7591295 -
Correlation of high lactate levels in human cervical cancer with incidence of metastasis
Cancer Res, 55 (21), 4757-9
PubMed 7585499 -
Transient perfusion in human melanoma xenografts
Br J Cancer, 71 (4), 789-93
DOI 10.1038/bjc.1995.153, PubMed 7536022 -
Interstitial fluid pressure in human melanoma xenografts. Relationship to fractional tumor water content, tumor size, and tumor volume-doubling time
Acta Oncol, 34 (3), 361-5
DOI 10.3109/02841869509093990, PubMed 7779424
Publications 1994
-
A nude rat model for neutron capture therapy of human intracerebral melanoma
Int J Radiat Oncol Biol Phys, 28 (5), 1079-88
DOI 10.1016/0360-3016(94)90481-2, PubMed 8175392 -
Oxygen consumption rate and mitochondrial density in human melanoma monolayer cultures and multicellular spheroids
Int J Cancer, 57 (4), 532-7
DOI 10.1002/ijc.2910570416, PubMed 8181856 -
Inactivation of human osteosarcoma cells in vitro by 211At-TP-3 monoclonal antibody: comparison with astatine-211-labeled bovine serum albumin, free astatine-211 and external-beam X rays
Radiat Res, 139 (2), 178-84
DOI 10.2307/3578662, PubMed 8052693 -
Analysis of the therapeutic gain in the treatment of human osteosarcoma microcolonies in vitro with 211At-labelled monoclonal antibody
Br J Cancer, 69 (6), 1000-5
DOI 10.1038/bjc.1994.196, PubMed 8198960 -
31P-nuclear magnetic resonance spectroscopy in vivo of four human melanoma xenograft lines: spin-lattice relaxation times
Radiother Oncol, 32 (1), 54-62
DOI 10.1016/0167-8140(94)90449-9, PubMed 7938679 -
Fractionation sensitivity (alpha/beta ratio) of human melanoma xenografts
Radiother Oncol, 33 (2), 133-8
DOI 10.1016/0167-8140(94)90067-1, PubMed 7708956 -
Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern
Br J Cancer, 70 (5), 804-12
DOI 10.1038/bjc.1994.403, PubMed 7947084 -
Step-down heating of human melanoma xenografts: effects of the tumour microenvironment
Br J Cancer, 70 (3), 453-8
DOI 10.1038/bjc.1994.327, PubMed 8080730 -
Non-invasive assessment of tumor oxygenation status by integrated 31P NMR spectroscopy and 1H NMR imaging
Adv Exp Med Biol, 345, 531-8
DOI 10.1007/978-1-4615-2468-7_71, PubMed 8079755 -
Magnetic resonance imaging of human melanoma xenografts in vivo: proton spin-lattice and spin-spin relaxation times versus fractional tumour water content and fraction of necrotic tumour tissue
Int J Radiat Biol, 65 (3), 387-401
DOI 10.1080/09553009414550451, PubMed 7908318 -
Hypoxia-induced resistance to doxorubicin and methotrexate in human melanoma cell lines in vitro
Int J Cancer, 58 (2), 258-62
DOI 10.1002/ijc.2910580219, PubMed 8026888 -
DNA double-strand break repair and radiation response in human tumour primary cultures
Int J Radiat Biol, 66 (3), 279-85
DOI 10.1080/09553009414551211, PubMed 7930830
Publications 1993
-
Prediction of treatment temperatures in clinical hyperthermia of locally advanced breast carcinoma: the use of contrast enhanced computed tomography
Int J Radiat Oncol Biol Phys, 26 (3), 451-7
DOI 10.1016/0360-3016(93)90963-v, PubMed 8390419 -
31P-nuclear magnetic resonance spectroscopy in vivo of six human melanoma xenograft lines: tumour bioenergetic status and blood supply
Br J Cancer, 68 (6), 1061-70
DOI 10.1038/bjc.1993.483, PubMed 8260356 -
Thermal dose and secondary tumour cell death
Int J Hyperthermia, 9 (5), 755-61
DOI 10.3109/02656739309032062, PubMed 8245585 -
Boron neutron capture therapy of intracerebral melanoma using boronophenylalanine as a capture agent
Cancer Res, 53 (14), 3308-13
PubMed 8324742 -
Expression of the chondroitin sulphate proteoglycan molecular complex in six human melanoma xenograft lines studied by flow cytometry and immunohistochemistry
Melanoma Res, 3 (3), 187-94
DOI 10.1097/00008390-199306000-00007, PubMed 7691291 -
Tumour necrotisation in nude mice xenografts by the reversible protein synthesis inhibitor zilascorb(2H)
Br J Cancer, 67 (4), 650-6
DOI 10.1038/bjc.1993.121, PubMed 8471421
Publications 1992
-
Blood flow in six human melanoma xenograft lines with different growth characteristics
Cancer Res, 52 (3), 584-92
PubMed 1732046 -
Comparative sensitivity of cells from human tumors and derivative tumor xenografts to radiation and heat treatments
J Natl Cancer Inst, 84 (19), 1517-24
DOI 10.1093/jnci/84.19.1517, PubMed 1433336 -
Retention of cellular radiation sensitivity in cell and xenograft lines established from human melanoma surgical specimens
Cancer Res, 52 (7), 1764-9
PubMed 1551106 -
Repopulation between radiation fractions in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 23 (1), 63-8
DOI 10.1016/0360-3016(92)90544-r, PubMed 1572831 -
Radiation sensitivity in vitro of primary tumors and metastatic lesions of malignant melanoma
Cancer Res, 52 (16), 4453-7
PubMed 1643637
Publications 1991
-
Temperature distribution in locally advanced breast carcinoma during hyperthermic treatment: relationship to perfusion, vascular density, and histology
Int J Radiat Oncol Biol Phys, 21 (2), 423-30
DOI 10.1016/0360-3016(91)90791-2, PubMed 1648045 -
Changes in temperatures and thermal doses with fraction number during hyperthermic treatment of locally advanced breast carcinoma
Int J Hyperthermia, 7 (6), 815-25
DOI 10.3109/02656739109056450, PubMed 1666900 -
The relevance of tumour and surrounding normal tissue vascular density in clinical hyperthermia of locally advanced breast carcinoma
Int J Radiat Biol, 60 (1-2), 189-93
DOI 10.1080/09553009114551821, PubMed 1677970 -
Relationships between thermal dose and heat-induced tissue and vascular damage after thermoradiotherapy of locally advanced breast carcinoma
Int J Hyperthermia, 7 (3), 403-15
DOI 10.3109/02656739109005006, PubMed 1919137 -
Fractionated thermochemotherapy in vivo of a C3H mouse mammary carcinoma
Radiother Oncol, 21 (3), 171-8
DOI 10.1016/0167-8140(91)90034-e, PubMed 1924852 -
Comparative imaging of structure and metabolites in tumours
Int J Radiat Biol, 60 (1-2), 147-59
DOI 10.1080/09553009114551741, PubMed 1677963 -
Heterogeneity in vascular architecture and heat-induced vascular damage of human melanoma xenograft lines established from different lesions in the same patient
Int J Radiat Biol, 60 (1-2), 183-7
DOI 10.1080/09553009114551801, PubMed 1677969 -
Influence of cellular radiation sensitivity on local tumor control of human melanoma xenografts given fractionated radiation treatment
Cancer Res, 51 (17), 4609-12
PubMed 1873806 -
Establishment in monolayer culture and characterization of four human melanoma cell lines
Virchows Arch B Cell Pathol Incl Mol Pathol, 60 (3), 189-97
DOI 10.1007/BF02899546, PubMed 1679270
Publications 1990
-
Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy, and cryospectrophotometry
Cancer Res, 50 (6), 1681-5
PubMed 2306721 -
NMR spectroscopy in prediction and monitoring of radiation response of tumours in vivo
Int J Radiat Biol, 57 (1), 1-5
DOI 10.1080/09553009014550281, PubMed 1967281 -
Heat sensitivity and thermotolerance in vitro of human breast carcinoma, malignant melanoma and squamous cell carcinoma of the head and neck
Br J Cancer, 61 (1), 22-8
DOI 10.1038/bjc.1990.6, PubMed 2297488 -
PLD-repair in human melanoma xenografts following single dose and fractionated irradiation
Br J Cancer, 61 (6), 856-60
DOI 10.1038/bjc.1990.191, PubMed 2372487 -
Establishment and characterization of six human melanoma xenograft lines
APMIS, 98 (10), 945-53
DOI 10.1111/j.1699-0463.1990.tb05019.x, PubMed 2245014 -
Heterogeneous radiation and heat sensitivity in vitro of human melanoma xenograft lines established from different lesions in the same patient. Comparisons with the radiation and heat sensitivity of cells isolated from the donor patient's surgical specimens
Int J Radiat Biol, 57 (6), 1113-22
DOI 10.1080/09553009014551231, PubMed 1971838
Publications 1989
-
Heterogeneity of glutathione content in human ovarian cancer
Cancer Res, 49 (19), 5244-8
PubMed 2766292 -
Thermochemotherapy in vivo of a C3H mouse mammary carcinoma: thermotolerant tumours
Int J Hyperthermia, 5 (5), 579-87
DOI 10.3109/02656738909140482, PubMed 2504842 -
Radiation biology of human tumour xenografts
Int J Radiat Biol, 56 (5), 573-81
DOI 10.1080/09553008914551761, PubMed 2573649 -
Local tumor control following single dose irradiation of human melanoma xenografts: relationship to cellular radiosensitivity and influence of an immune response by the athymic mouse
Cancer Res, 49 (12), 3163-7
PubMed 2655893 -
Hypoxia and reoxygenation in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 17 (1), 81-9
DOI 10.1016/0360-3016(89)90374-x, PubMed 2745212 -
Influence of cellular, microenvironmental, and growth parameters on thermotolerance kinetics in vivo in human melanoma xenografts
Cancer Res, 49 (18), 5027-32
PubMed 2766273 -
31P NMR spectroscopy and HbO2 cryospectrophotometry in prediction of tumor radioresistance caused by hypoxia
Int J Radiat Oncol Biol Phys, 16 (4), 919-23
DOI 10.1016/0360-3016(89)90887-0, PubMed 2703397 -
Growth and radiation sensitivity of the MLS human ovarian carcinoma cell line grown as multicellular spheroids and xenografted tumours
Br J Cancer, 59 (1), 28-35
DOI 10.1038/bjc.1989.7, PubMed 2757922
Publications 1988
-
Effects of heat treatment in vitro and in vivo on human melanoma xenografts
Recent Results Cancer Res, 109, 183-97
DOI 10.1007/978-3-642-83263-5_21, PubMed 3175290 -
Relationship between changes in antigen expression and protein synthesis in human melanoma cells after hyperthermia and photodynamic treatment
Br J Cancer, 58 (3), 306-13
DOI 10.1038/bjc.1988.209, PubMed 3179182 -
Cryospectrophotometric determination of tumor intravascular oxyhemoglobin saturations: dependence on vascular geometry and tumor growth
J Natl Cancer Inst, 80 (20), 1612-9
DOI 10.1093/jnci/80.20.1612, PubMed 3193479 -
Thermochemotherapy in vivo of a C3H mouse mammary carcinoma: single fraction heat and drug treatment
Eur J Cancer Clin Oncol, 24 (10), 1661-9
DOI 10.1016/0277-5379(88)90060-0, PubMed 3145205 -
31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia
Cancer Res, 48 (19), 5440-6
PubMed 3416301 -
31P NMR spectroscopy measurements of human ovarian carcinoma xenografts: relationship to tumour volume, growth rate, necrotic fraction and differentiation status
Radiother Oncol, 12 (4), 315-26
DOI 10.1016/0167-8140(88)90021-7, PubMed 3187070 -
Intracapillary HbO2 saturations in murine tumours and human tumour xenografts measured by cryospectrophotometry: relationship to tumour volume, tumour pH and fraction of radiobiologically hypoxic cells
Br J Cancer, 57 (5), 494-502
DOI 10.1038/bjc.1988.113, PubMed 3395554 -
31P NMR spectroscopy in vivo of two murine tumor lines with widely different fractions of radiobiologically hypoxic cells
Int J Radiat Biol, 54 (4), 635-49
DOI 10.1080/09553008814552071, PubMed 2902161 -
Radiation sensitivity of human ovarian carcinoma cell lines in vitro: effects of growth factors and hormones, basement membrane, and intercellular contact
Int J Radiat Oncol Biol Phys, 15 (4), 921-9
DOI 10.1016/0360-3016(88)90127-7, PubMed 3182331
Publications 1987
-
Radioresponsiveness of human melanoma xenografts given fractionated irradiation in vivo--relationship to the initial slope of the cell survival curves in vitro
Radiother Oncol, 9 (1), 45-56
DOI 10.1016/s0167-8140(87)80218-9, PubMed 3602429 -
Radiation sensitivity in vitro of cells isolated from human tumor surgical specimens
Cancer Res, 47 (1), 106-10
PubMed 3791195
Publications 1986
-
Radiation biology of malignant melanoma
Acta Radiol Oncol, 25 (1), 1-10
DOI 10.3109/02841868609136368, PubMed 3010642 -
Growth and radiosensitivity of malignant melanoma multicellular spheroids initiated directly from surgical specimens of tumours in man
Br J Cancer, 54 (4), 569-78
DOI 10.1038/bjc.1986.211, PubMed 3778801 -
Heterogeneity in radiosensitization by heat of cloned cell lines derived from a single human melanoma xenograft
Int J Radiat Biol Relat Stud Phys Chem Med, 50 (1), 93-102
DOI 10.1080/09553008614550471, PubMed 3487528 -
Differences in thermosensitization among cloned cell lines isolated from a single human melanoma xenograft
Radiat Res, 106 (2), 147-55
DOI 10.2307/3576788, PubMed 3704108 -
Arrhenius analysis of the heat response in vivo and in vitro of human melanoma xenografts
Int J Hyperthermia, 2 (4), 359-68
DOI 10.3109/02656738609004966, PubMed 3805805 -
Primary and secondary cell death in human melanoma xenografts following hyperthermic treatment
Cancer Res, 46 (1), 355-61
PubMed 3940201 -
Radiation response of human melanoma multicellular spheroids measured as single cell survival, growth delay, and spheroid cure: comparisons with the parent tumor xenograft
Int J Radiat Oncol Biol Phys, 12 (6), 975-82
DOI 10.1016/0360-3016(86)90394-9, PubMed 3721939 -
Radiation response of multicellular spheroids initiated from five human melanoma xenograft lines. Relationship to the radioresponsiveness in vivo
Br J Radiol, 59 (706), 1023-9
DOI 10.1259/0007-1285-59-706-1023, PubMed 3768626 -
Growth characteristics of human melanoma multicellular spheroids in liquid-overlay culture: comparisons with the parent tumour xenografts
Cell Tissue Kinet, 19 (2), 205-16
DOI 10.1111/j.1365-2184.1986.tb00731.x, PubMed 3698078
Publications 1985
-
Hyperthermia-induced changes in antigen expression on human FME melanoma cells
Cancer Res, 45 (9), 4109-14
PubMed 3896477 -
Human tumour xenografts in radiotherapeutic research
Radiother Oncol, 3 (1), 35-46
DOI 10.1016/s0167-8140(85)80007-4, PubMed 3975440 -
Heterogeneity in heat sensitivity and development of thermotolerance of cloned cell lines derived from a single human melanoma xenograft
Int J Hyperthermia, 1 (1), 85-96
DOI 10.3109/02656738509029276, PubMed 3837083 -
Tumour growth delay following single dose irradiation of human melanoma xenografts. Correlations with tumour growth parameters, vascular structure and cellular radiosensitivity
Br J Cancer, 51 (2), 201-10
DOI 10.1038/bjc.1985.30, PubMed 3966977 -
Heat response of human melanoma multicellular spheroids: comparisons with single cells and xenografted tumors
Radiat Res, 102 (3), 324-35
DOI 10.2307/3576708, PubMed 4070547 -
Survival curves after X-ray and heat treatments for melanoma cells derived directly from surgical specimens of tumours in man
Radiother Oncol, 4 (1), 33-44
DOI 10.1016/s0167-8140(85)80060-8, PubMed 4035001 -
Vascular structure of the C3H mammary carcinoma, the B16 melanoma and the Lewis lung carcinoma in syngeneic, conventional mice and congenitally athymic mice
Eur J Cancer Clin Oncol, 21 (4), 499-505
DOI 10.1016/0277-5379(85)90044-6, PubMed 4007018
Publications 1984
-
A transparent chamber for the dorsal skin fold of athymic mice
Exp Cell Biol, 52 (4), 260-8
DOI 10.1159/000163269, PubMed 6734890 -
Antigen expression in human melanoma cells in relation to growth conditions and cell-cycle distribution
Int J Cancer, 33 (2), 167-71
DOI 10.1002/ijc.2910330203, PubMed 6693198 -
Growth and vascular structure of human melanoma xenografts
Cell Tissue Kinet, 17 (1), 91-101
DOI 10.1111/j.1365-2184.1984.tb00571.x, PubMed 6692466 -
Response to heat treatment (42.5 degrees C) in vivo and in vitro of five human melanoma xenografts
Br J Radiol, 57 (683), 1023-32
DOI 10.1259/0007-1285-57-683-1023, PubMed 6535617 -
Development of thermotolerance in a human melanoma xenograft
Cancer Res, 44 (2), 525-30
PubMed 6692358 -
Differential responses to radiation and hyperthermia of cloned cell lines derived from a single human melanoma xenograft
Int J Radiat Oncol Biol Phys, 10 (6), 857-64
DOI 10.1016/0360-3016(84)90388-2, PubMed 6735769 -
Hyperthermic radiosensitization of cells from a human melanoma xenograft
Radiat Res, 99 (1), 59-72
DOI 10.2307/3576447, PubMed 6739727 -
Micronucleus formation in human melanoma xenografts following exposure to hyperthermia
Radiat Environ Biophys, 23 (1), 51-60
DOI 10.1007/BF01326736, PubMed 6709827 -
Heat sensitivity and thermotolerance in cells from five human melanoma xenografts
Cancer Res, 44 (10), 4347-54
PubMed 6467196 -
Tumour growth delay, cell inactivation and vascular damage following hyperthermic treatment of a human melanoma xenograft
Eur J Cancer Clin Oncol, 20 (10), 1295-1305
DOI 10.1016/0277-5379(84)90259-1, PubMed 6541585 -
Radiation and heat sensitivity of cells from two slowly growing human melanoma xenografts
Br J Cancer, 49 (6), 745-52
DOI 10.1038/bjc.1984.117, PubMed 6733021 -
Vascular changes in a human malignant melanoma xenograft following single-dose irradiation
Radiat Res, 98 (1), 115-28
DOI 10.2307/3576056, PubMed 6718687
Publications 1983
-
Spontaneous alteration in growth rates of two human melanoma xenografts. Concurrent changes in chemosensitivity
Eur J Cancer Clin Oncol, 19 (8), 1175-8
DOI 10.1016/0277-5379(83)90046-9, PubMed 6684563 -
Radiosensitivity of the cells of an established human melanoma cell line and the parent melanoma xenograft
Int J Radiat Biol Relat Stud Phys Chem Med, 44 (5), 447-54
DOI 10.1080/09553008314551431, PubMed 6605949 -
Radiation and heat sensitivity of cells from human melanoma xenografts. Lack of correlations with tumour growth parameters
Eur J Cancer Clin Oncol, 19 (3), 427-32
DOI 10.1016/0277-5379(83)90142-6, PubMed 6683180 -
Tumour control following single-dose irradiation of a human melanoma xenograft
Eur J Cancer Clin Oncol, 19 (8), 1127-31
DOI 10.1016/0277-5379(83)90038-x, PubMed 6684558 -
Intercellular contact and the radiation response of cells of human melanoma xenografts
Int J Radiat Oncol Biol Phys, 9 (2), 191-5
DOI 10.1016/0360-3016(83)90098-6, PubMed 6833022
Publications 1982
-
Effect of hyperthermia on human melanoma cells heated either as solid tumors in athymic nude mice or in vitro
Cancer, 50 (7), 1304-8
DOI 10.1002/1097-0142(19821001)50:7<1304::aid-cncr2820500715>3.0.co;2-h, PubMed 7104974 -
Growth characteristics of human melanoma xenografts
Cell Tissue Kinet, 15 (5), 545-54
DOI 10.1111/j.1365-2184.1982.tb01576.x, PubMed 7127402 -
Vascular structure of five human malignant melanomas grown in athymic nude mice
Br J Cancer, 46 (4), 557-67
DOI 10.1038/bjc.1982.240, PubMed 7138764
Publications 1981
-
Radiation response of two human malignant melanomas grown in athymic nude mice
Eur J Cancer, 17 (5), 527-32
DOI 10.1016/0014-2964(81)90054-2, PubMed 7297592 -
Sensitising effect of misonidazole on NHIK 1922 cells irradiated in vitro or as solid tumour in athymic nude mice
Acta Radiol Oncol, 20 (2), 101-8
DOI 10.3109/02841868109130428, PubMed 6270961 -
Radiation response of the cells of a human malignant melanoma xenograft. Effect of hypoxic cell radiosensitizers
Radiat Res, 87 (3), 670-83
DOI 10.2307/3575529, PubMed 7280191 -
Broad-shouldered survival curves of a human melanoma xenograft. Implications for radiation therapy in the absence and presence of misonidazole
Acta Radiol Oncol, 20 (4), 261-5
DOI 10.3109/02841868109130204, PubMed 6277155 -
Radiation response in vitro of cells from five human malignant melanoma xenografts
Int J Radiat Biol Relat Stud Phys Chem Med, 40 (6), 677-80
DOI 10.1080/09553008114551671, PubMed 6978304 -
Response of human malignant melanoma xenografts to hyperthermia: effect of vascular occlusion
Int J Radiat Oncol Biol Phys, 7 (12), 1685-7
DOI 10.1016/0360-3016(81)90193-0, PubMed 7333910
Publications 1980
-
Radiosensitizing effect of misonidazole in acute and fractionated irradiation of a human osteosarcoma xenograft
Int J Radiat Oncol Biol Phys, 6 (9), 1163-7
DOI 10.1016/0360-3016(80)90169-8, PubMed 6936394 -
Radiosensitization by misonidazole of a human malignant melanoma grown in athymic nude mice
Br J Radiol, 53 (631), 678-86
DOI 10.1259/0007-1285-53-631-678, PubMed 7426890 -
Effect of single dose irradiation on the proliferation kinetics in a human malignant melanoma in athymic nude mice
Acta Radiol Oncol, 19 (4), 261-9
DOI 10.3109/02841868009130163, PubMed 6257048 -
The proliferation kinetics of NHIK 1922 cells in vitro and in solid tumours in athymic mice
Cell Tissue Kinet, 13 (2), 163-71
DOI 10.1111/j.1365-2184.1980.tb00459.x, PubMed 7363302
Publications 1979
-
Radiosensitizing effect of misonidazole in fractionated gamma-ray treatment of a human malignant melanoma grown in athymic nude mice
Br J Radiol, 52 (617), 393-7
DOI 10.1259/0007-1285-52-617-393, PubMed 444837
Publications 1978
-
The radiosensitizing effect of metronidazole and misonidazole (Ro-07-0582) on a human malignant melanoma grown in the athymic mutant nude mouse
Br J Radiol, 51 (605), 381-6
DOI 10.1259/0007-1285-51-605-381, PubMed 638410
Publications 1977
-
Effect of clinically relevant irradiation regimes on human malignant melanomas grown in athymic nude mice
Acta Radiol Ther Phys Biol, 16 (3), 273-80
DOI 10.3109/02841867709133947, PubMed 906896 -
Effect of cobalt-60 gamma rays and DTIC (5-(3,3 dimethyl-1-triazeno)-imidazole-r-carboxamide) on human malignant melanomas grown in athymic nude mice
Br J Radiol, 50 (593), 314-20
DOI 10.1259/0007-1285-50-593-314, PubMed 861450 -
Cell proliferation kinetics in two human tumors grown in athymic nude mice
Virchows Arch B Cell Pathol, 24 (3), 219-25
DOI 10.1007/BF02889281, PubMed 410153
Publications 1976
-
A pilot experiment to compare regression of transplants of two different human tumors in athymic nude mice following single exposures to 60co radiation
Strahlentherapie, 152 (5), 477-81
PubMed 996892