
Adam Brian Robertson
- Group Leader; PhD
- +47 23 07 40 65
Oslo University Hospital
Department of Molecular Microbiology
Building B, 3rd floor, Room B2.3069
Sognsvannsveien 20
NO-0027
Oslo
Norway
Publications 2019
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131
Publications 2016
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Free Radic Biol Med, 107, 62-68
DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639
Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions
Biochemistry, 55 (41), 5781-5789
DOI 10.1021/acs.biochem.6b00801, PubMed 27653243
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
Nat Commun, 7, 10806
DOI 10.1038/ncomms10806, PubMed 26932196
Publications 2014
DNA metabolism: bases of DNA repair and regulation
Nat Chem Biol, 10 (7), 487-8
DOI 10.1038/nchembio.1553, PubMed 24937064
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Nucleic Acids Res, 42 (21), 13280-93
DOI 10.1093/nar/gku1032, PubMed 25355512
Publications 2013
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141
Publications 2012
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads
Nat Protoc, 7 (2), 340-50
DOI 10.1038/nprot.2011.443, PubMed 22281869
Reconstitution of the very short patch repair pathway from Escherichia coli
J Biol Chem, 287 (39), 32953-66
DOI 10.1074/jbc.M112.384321, PubMed 22846989
Publications 2011
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Res, 39 (8), e55
DOI 10.1093/nar/gkr051, PubMed 21300643
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
Biochem Biophys Res Commun, 411 (1), 40-3
DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242
Publications 2009
DNA repair in mammalian cells: Base excision repair: the long and short of it
Cell Mol Life Sci, 66 (6), 981-93
DOI 10.1007/s00018-009-8736-z, PubMed 19153658
Publications 2006
The UvrD helicase and its modulation by the mismatch repair protein MutL
Nucleic Acids Res, 34 (15), 4089-97
DOI 10.1093/nar/gkl450, PubMed 16935885
The DNA binding activity of MutL is required for methyl-directed mismatch repair in Escherichia coli
J Biol Chem, 281 (13), 8399-408
DOI 10.1074/jbc.M509184200, PubMed 16446358
MutL-catalyzed ATP hydrolysis is required at a post-UvrD loading step in methyl-directed mismatch repair
J Biol Chem, 281 (29), 19949-59
DOI 10.1074/jbc.M601604200, PubMed 16690604