Adam Brian Robertson

  • Group Leader PhD
  • +47 23 07 40 65
Oslo University Hospital

Department of Molecular Microbiology

Building B, 3rd floor, Room B2.3069

Sognsvannsveien 20

Publications 2016

Klungland A, Robertson AB (2016)
Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
Free Radic Biol Med, 107, 62-68
DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639

Vander Zanden CM, Rowe RK, Broad AJ, Robertson AB, Ho PS (2016)
Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions
Biochemistry, 55 (41), 5781-5789
DOI 10.1021/acs.biochem.6b00801, PubMed 27653243

Weber AR, Krawczyk C, Robertson AB, Kuśnierczyk A, Vågbø CB, Schuermann D, Klungland A, Schär P (2016)
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
Nat Commun, 7, 10806
DOI 10.1038/ncomms10806, PubMed 26932196

Publications 2014

Robertson AB, Dahl JA, Klungland A (2014)
DNA metabolism: bases of DNA repair and regulation
Nat Chem Biol, 10 (7), 487-8
DOI 10.1038/nchembio.1553, PubMed 24937064

Robertson AB, Robertson J, Fusser M, Klungland A (2014)
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Nucleic Acids Res, 42 (21), 13280-93
DOI 10.1093/nar/gku1032, PubMed 25355512

Publications 2013

Solberg A, Robertson AB, Aronsen JM, Rognmo Ø, Sjaastad I, Wisløff U, Klungland A (2013)
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141

Publications 2012

Robertson AB, Dahl JA, Ougland R, Klungland A (2012)
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads
Nat Protoc, 7 (2), 340-50
DOI 10.1038/nprot.2011.443, PubMed 22281869

Robertson AB, Matson SW (2012)
Reconstitution of the very short patch repair pathway from Escherichia coli
J Biol Chem, 287 (39), 32953-66
DOI 10.1074/jbc.M112.384321, PubMed 22846989

Publications 2011

Robertson AB, Dahl JA, Vågbø CB, Tripathi P, Krokan HE, Klungland A (2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
Nucleic Acids Res, 39 (8), e55
DOI 10.1093/nar/gkr051, PubMed 21300643

Robertson J, Robertson AB, Klungland A (2011)
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
Biochem Biophys Res Commun, 411 (1), 40-3
DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242

Publications 2009

Robertson AB, Klungland A, Rognes T, Leiros I (2009)
DNA repair in mammalian cells: Base excision repair: the long and short of it
Cell Mol Life Sci, 66 (6), 981-93
DOI 10.1007/s00018-009-8736-z, PubMed 19153658

Publications 2006

Matson SW, Robertson AB (2006)
The UvrD helicase and its modulation by the mismatch repair protein MutL
Nucleic Acids Res, 34 (15), 4089-97
DOI 10.1093/nar/gkl450, PubMed 16935885

Robertson A, Pattishall SR, Matson SW (2006)
The DNA binding activity of MutL is required for methyl-directed mismatch repair in Escherichia coli
J Biol Chem, 281 (13), 8399-408
DOI 10.1074/jbc.M509184200, PubMed 16446358

Robertson AB, Pattishall SR, Gibbons EA, Matson SW (2006)
MutL-catalyzed ATP hydrolysis is required at a post-UvrD loading step in methyl-directed mismatch repair
J Biol Chem, 281 (29), 19949-59
DOI 10.1074/jbc.M601604200, PubMed 16690604

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