Publications 2021

Holme SS, Kilian K, Eggesbø HB, Moen JM, Molberg Ø (2021)
Impact of baseline clinical and radiological features on outcome of chronic rhinosinusitis in granulomatosis with polyangiitis
Arthritis Res Ther, 23 (1), 18
DOI 10.1186/s13075-020-02401-x, PubMed 33430923

Publications 2020

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Molberg Ø, Hoffmann-Vold AM (2020)
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
Rheumatology (Oxford), 59 (10), 2920-2929
DOI 10.1093/rheumatology/keaa026, PubMed 32097470

Hoffmann-Vold AM, Fretheim H, Didriksen H, Molberg Ø (2020)
The potential of fecal microbiota transplantation in systemic sclerosis
Expert Rev Clin Immunol, 16 (2), 117-118
DOI 10.1080/1744666X.2019.1707665, PubMed 31858856

Hoffmann-Vold AM, Molberg Ø (2020)
Detection, screening, and classification of interstitial lung disease in patients with systemic sclerosis
Curr Opin Rheumatol, 32 (6), 497-504
DOI 10.1097/BOR.0000000000000741, PubMed 32890027

Holme SS, Moen JM, Kilian K, Eggesbø HB, Molberg Ø (2020)
Impact of Paranasal Sinus Surgery in Granulomatosis With Polyangiitis: A Longitudinal Computed Tomography Study
Laryngoscope, 130 (8), E460-E468
DOI 10.1002/lary.28639, PubMed 32243590

Sandling JK, Pucholt P, Hultin Rosenberg L, Farias FHG, Kozyrev SV, Eloranta ML, Alexsson A, Bianchi M, Padyukov L, Bengtsson C, Jonsson R, Omdal R, Lie BA, Massarenti L, Steffensen R, Jakobsen MA, Lillevang ST, ImmunoArray Development Consortium and DISSECT consortium, Lerang K, Molberg Ø, Voss A, Troldborg A, Jacobsen S, Syvänen AC, Jönsen A et al. (2020)
Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing
Ann Rheum Dis, 80 (1), 109-117
DOI 10.1136/annrheumdis-2020-218636, PubMed 33037003

Sikkeland LI, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2020)
Lung CD4+ T cells in patients with lung fibrosis produce pro-fibrotic IL-13 together with IFNγ
Eur Respir J (in press)
DOI 10.1183/13993003.00983-2020, PubMed 33154027

Publications 2019

Cavagna L, Trallero-Araguás E, Meloni F, Cavazzana I, Rojas-Serrano J, Feist E, Zanframundo G, Morandi V, Meyer A, Pereira da Silva JA, Matos Costa CJ, Molberg O, Andersson H, Codullo V, Mosca M, Barsotti S, Neri R, Scirè C, Govoni M, Furini F, Lopez-Longo FJ, Martinez-Barrio J, Schneider U, Lorenz HM, Doria A et al. (2019)
Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course
J Clin Med, 8 (11)
DOI 10.3390/jcm8112013, PubMed 31752231

Christophersen A, Lund EG, Snir O, Solà E, Kanduri C, Dahal-Koirala S, Zühlke S, Molberg Ø, Utz PJ, Rohani-Pichavant M, Simard JF, Dekker CL, Lundin KEA, Sollid LM, Davis MM (2019)
Distinct phenotype of CD4⁺ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136

Elhai M, Hoffmann-Vold AM, Avouac J, Pezet S, Cauvet A, Leblond A, Fretheim H, Garen T, Kuwana M, Molberg Ø, Allanore Y (2019)
Performance of Candidate Serum Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease
Arthritis Rheumatol, 71 (6), 972-982
DOI 10.1002/art.40815, PubMed 30624031

Garen T, Lerang K, Hoffmann-Vold AM, Andersson H, Midtvedt Ø, Brunborg C, Kilian K, Gudbrandsson B, Gunnarsson R, Norby G, Chaudhary A, Thoen J, Forseth KØ, Fresjar K, Førre Ø, Haugen M, Haga HJ, Gran JT, Gilboe IM, Molberg Ø, Palm Ø (2019)
Mortality and causes of death across the systemic connective tissue diseases and the primary systemic vasculitides
Rheumatology (Oxford), 58 (2), 313-320
DOI 10.1093/rheumatology/key285, PubMed 30281089

Hoffmann-Vold AM, Didriksen H, Molberg Ø (2019)
Reply
Arthritis Rheumatol, 71 (4), 655-656
DOI 10.1002/art.40816, PubMed 30663863

Hoffmann-Vold AM, Fretheim H, Halse AK, Seip M, Bitter H, Wallenius M, Garen T, Salberg A, Brunborg C, Midtvedt Ø, Lund MB, Aaløkken TM, Molberg Ø (2019)
Tracking Impact of Interstitial Lung Disease in Systemic Sclerosis in a Complete Nationwide Cohort
Am J Respir Crit Care Med, 200 (10), 1258-1266
DOI 10.1164/rccm.201903-0486OC, PubMed 31310156

Holme SS, Moen JM, Kilian K, Haukeland H, Molberg Ø, Eggesbø HB (2019)
Development of CT-based methods for longitudinal analyses of paranasal sinus osteitis in granulomatosis with polyangiitis
BMC Med Imaging, 19 (1), 13
DOI 10.1186/s12880-019-0315-7, PubMed 30717680

Reppe Moe SE, Molberg Ø, Strøm EH, Lerang K (2019)
Assessing the relative impact of lupus nephritis on mortality in a population-based systemic lupus erythematosus cohort
Lupus, 28 (7), 818-825
DOI 10.1177/0961203319847275, PubMed 31072277

Risum K, Edvardsen E, Godang K, Selvaag AM, Hansen BH, Molberg Ø, Bollerslev J, Holm I, Dagfinrud H, Sanner H (2019)
Physical Fitness in Patients With Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis Diagnosed in the Era of Biologics: A Controlled Cross-Sectional Study
Arthritis Care Res (Hoboken), 71 (12), 1611-1620
DOI 10.1002/acr.23818, PubMed 30474929

Rothwell S, Chinoy H, Lamb JA, Miller FW, Rider LG, Wedderburn LR, McHugh NJ, Mammen AL, Betteridge ZE, Tansley SL, Bowes J, Vencovský J, Deakin CT, Dankó K, Vidya L, Selva-O'Callaghan A, Pachman LM, Reed AM, Molberg Ø, Benveniste O, Mathiesen PR, Radstake TRDJ, Doria A, de Bleecker J, Lee AT et al. (2019)
Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups
Ann Rheum Dis, 78 (7), 996-1002
DOI 10.1136/annrheumdis-2019-215046, PubMed 31138531

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Midtvedt Ø, Garen T, Dalen H, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2019)
Systolic Dysfunction in Systemic Sclerosis: Prevalence and Prognostic Implications
ACR Open Rheumatol, 1 (4), 258-266
DOI 10.1002/acr2.1037, PubMed 31777802

Publications 2018

Guderud K, Mæhlen MT, Nordang GBN, Viken MK, Andreassen BK, Molberg Ø, Flåm ST, Lie BA (2018)
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
J Rheumatol, 45 (9), 1211-1219
DOI 10.3899/jrheum.170769, PubMed 29858238

Hoffmann-Vold AM, Fretheim H, Midtvedt Ø, Kilian K, Angelshaug M, Chaudhary A, Gunnarsson R, Brunborg C, Garen T, Andreassen AK, Gude E, Molberg Ø (2018)
Frequencies of borderline pulmonary hypertension before and after the DETECT algorithm: results from a prospective systemic sclerosis cohort
Rheumatology (Oxford), 57 (3), 480-487
DOI 10.1093/rheumatology/kex435, PubMed 29237073

Hoffmann-Vold AM, Hesselstrand R, Fretheim H, Ueland T, Andreassen AK, Brunborg C, Palchevskiy V, Midtvedt Ø, Garen T, Aukrust P, Belperio JA, Molberg Ø (2018)
CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis
Arthritis Rheumatol, 70 (10), 1644-1653
DOI 10.1002/art.40534, PubMed 29687634

Hoffmann-Vold AM, Molberg Ø (2018)
CCL21 as a potential biomarker for pulmonary arterial hypertension in systemic sclerosis
Arthritis Rheumatol (in press)
DOI 10.1002/art.40740, PubMed 30281215

Hoffmann-Vold AM, Weigt SS, Palchevskiy V, Volkmann E, Saggar R, Li N, Midtvedt Ø, Lund MB, Garen T, Fishbein MC, Ardehali A, Ross DJ, Ueland T, Aukrust P, Lynch JP, Elashoff RM, Molberg Ø, Belperio JA (2018)
Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis
PLoS One, 13 (11), e0206545
DOI 10.1371/journal.pone.0206545, PubMed 30457999

Oma I, Olstad OK, Andersen JK, Lyberg T, Molberg Ø, Fostad I, Wang Fagerland M, Almdahl SM, Rynning SE, Yndestad A, Aukrust P, Whist JE, Hollan I (2018)
Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
PLoS One, 13 (8), e0202346
DOI 10.1371/journal.pone.0202346, PubMed 30138371

Reiseter S, Gunnarsson R, Mogens Aaløkken T, Lund MB, Mynarek G, Corander J, Haydon J, Molberg Ø (2018)
Progression and mortality of interstitial lung disease in mixed connective tissue disease: a long-term observational nationwide cohort study
Rheumatology (Oxford), 57 (2), 255-262
DOI 10.1093/rheumatology/kex077, PubMed 28379478

Risum K, Hansen BH, Selvaag AM, Molberg Ø, Dagfinrud H, Sanner H (2018)
Physical activity in patients with oligo- and polyarticular juvenile idiopathic arthritis diagnosed in the era of biologics: a controlled cross-sectional study
Pediatr Rheumatol Online J, 16 (1), 64
DOI 10.1186/s12969-018-0281-6, PubMed 30333025

Tennøe AH, Murbræch K, Andreassen JC, Fretheim H, Garen T, Gude E, Andreassen A, Aakhus S, Molberg Ø, Hoffmann-Vold AM (2018)
Left Ventricular Diastolic Dysfunction Predicts Mortality in Patients With Systemic Sclerosis
J Am Coll Cardiol, 72 (15), 1804-1813
DOI 10.1016/j.jacc.2018.07.068, PubMed 30286924

Publications 2017

Andersson H, Kirkhus E, Garen T, Walle-Hansen R, Merckoll E, Molberg Ø (2017)
Comparative analyses of muscle MRI and muscular function in anti-synthetase syndrome patients and matched controls: a cross-sectional study
Arthritis Res Ther, 19 (1), 17
DOI 10.1186/s13075-017-1219-y, PubMed 28122635

Avouac J, Guignabert C, Hoffmann-Vold AM, Ruiz B, Dorfmuller P, Pezet S, Amar O, Tu L, Van Wassenhove J, Sadoine J, Launay D, Elhai M, Cauvet A, Subramaniam A, Resnick R, Hachulla E, Molberg Ø, Kahan A, Humbert M, Allanore Y (2017)
Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis
Arthritis Rheumatol, 69 (11), 2209-2221
DOI 10.1002/art.40229, PubMed 28805015

Gudbrandsson B, Molberg Ø, Palm Ø (2017)
TNF inhibitors appear to inhibit disease progression and improve outcome in Takayasu arteritis; an observational, population-based time trend study
Arthritis Res Ther, 19 (1), 99
DOI 10.1186/s13075-017-1316-y, PubMed 28521841

Gudbrandsson B, Wallenius M, Garen T, Henriksen T, Molberg Ø, Palm Ø (2017)
Takayasu Arteritis and Pregnancy: A Population-Based Study on Outcomes and Mother/Child-Related Concerns
Arthritis Care Res (Hoboken), 69 (9), 1384-1390
DOI 10.1002/acr.23146, PubMed 27813289

Hoffmann-Vold AM, Midtvedt Ø, Tennøe AH, Garen T, Lund MB, Aaløkken TM, Andreassen AK, Elhage F, Brunborg C, Taraldsrud E, Molberg Ø (2017)
Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort
J Rheumatol, 44 (4), 459-465
DOI 10.3899/jrheum.160867, PubMed 28089974

Reiseter S, Gunnarsson R, Corander J, Haydon J, Lund MB, Aaløkken TM, Taraldsrud E, Hetlevik SO, Molberg Ø (2017)
Disease evolution in mixed connective tissue disease: results from a long-term nationwide prospective cohort study
Arthritis Res Ther, 19 (1), 284
DOI 10.1186/s13075-017-1494-7, PubMed 29268795

Rothwell S, Cooper RG, Lundberg IE, Gregersen PK, Hanna MG, Machado PM, Herbert MK, Pruijn GJM, Lilleker JB, Roberts M, Bowes J, Seldin MF, Vencovsky J, Danko K, Limaye V, Selva-O'Callaghan A, Platt H, Molberg Ø, Benveniste O, Radstake TRDJ, Doria A, De Bleecker J, De Paepe B, Gieger C, Meitinger T et al. (2017)
Immune-Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum
Arthritis Rheumatol, 69 (5), 1090-1099
DOI 10.1002/art.40045, PubMed 28086002

Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J (2017)
Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
BMJ Open Gastroenterol, 4 (1), e000134
DOI 10.1136/bmjgast-2017-000134, PubMed 28761687

Publications 2016

Andersson H, Aaløkken TM, Günther A, Mynarek GK, Garen T, Lund MB, Molberg Ø (2016)
Pulmonary Involvement in the Antisynthetase Syndrome: A Comparative Cross-sectional Study
J Rheumatol, 43 (6), 1107-13
DOI 10.3899/jrheum.151067, PubMed 27036381

Carmona FD, Vaglio A, Mackie SL, Hernández-Rodríguez J, Monach PA, Castañeda S, Solans R, Morado IC, Narváez J, Ramentol-Sintas M, Pease CT, Dasgupta B, Watts R, Khalidi N, Langford CA, Ytterberg S, Boiardi L, Beretta L, Govoni M, Emmi G, Bonatti F, Cimmino MA, Witte T, Neumann T, Holle J et al. (2016)
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis
Am J Hum Genet, 100 (1), 64-74
DOI 10.1016/j.ajhg.2016.11.013, PubMed 28041642

Elhai M, Avouac J, Hoffmann-Vold AM, Ruzehaji N, Amiar O, Ruiz B, Brahiti H, Ponsoye M, Fréchet M, Burgevin A, Pezet S, Sadoine J, Guilbert T, Nicco C, Akiba H, Heissmeyer V, Subramaniam A, Resnick R, Molberg Ø, Kahan A, Chiocchia G, Allanore Y (2016)
OX40L blockade protects against inflammation-driven fibrosis
Proc Natl Acad Sci U S A, 113 (27), E3901-10
DOI 10.1073/pnas.1523512113, PubMed 27298374

Gudbrandsson B, Molberg Ø, Garen T, Palm Ø (2016)
Prevalence, Incidence, and Disease Characteristics of Takayasu Arteritis by Ethnic Background: Data From a Large, Population-Based Cohort Resident in Southern Norway
Arthritis Care Res (Hoboken), 69 (2), 278-285
DOI 10.1002/acr.22931, PubMed 27159262

Gunnarsson R, Hetlevik SO, Lilleby V, Molberg Ø (2016)
Mixed connective tissue disease
Best Pract Res Clin Rheumatol, 30 (1), 95-111
DOI 10.1016/j.berh.2016.03.002, PubMed 27421219

Hoffmann-Vold AM, Tennøe AH, Garen T, Midtvedt Ø, Abraityte A, Aaløkken TM, Lund MB, Brunborg C, Aukrust P, Ueland T, Molberg Ø (2016)
High Level of Chemokine CCL18 Is Associated With Pulmonary Function Deterioration, Lung Fibrosis Progression, and Reduced Survival in Systemic Sclerosis
Chest, 150 (2), 299-306
DOI 10.1016/j.chest.2016.03.004, PubMed 26997242

Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH (2016)
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
Liver Int, 37 (3), 458-465
DOI 10.1111/liv.13238, PubMed 27558072

López-Isac E, Martín JE, Assassi S, Simeón CP, Carreira P, Ortego-Centeno N, Freire M, Beltrán E, Narváez J, Alegre-Sancho JJ, Spanish Scleroderma Group, Fernández-Gutiérrez B, Balsa A, Ortiz AM, González-Gay MA, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A, Witte T, Hunzelmann N, Distler JH, Riekemasten G et al. (2016)
Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies
Arthritis Rheumatol, 68 (9), 2338-44
DOI 10.1002/art.39730, PubMed 27111665

Molberg Ø, Dobloug C (2016)
Epidemiology of sporadic inclusion body myositis
Curr Opin Rheumatol, 28 (6), 657-60
DOI 10.1097/BOR.0000000000000327, PubMed 27541181

Molberg Ø, Hoffmann-Vold AM (2016)
Interstitial lung disease in systemic sclerosis: progress in screening and early diagnosis
Curr Opin Rheumatol, 28 (6), 613-8
DOI 10.1097/BOR.0000000000000323, PubMed 27387267

Oma I, Andersen JK, Lyberg T, Molberg Ø, Whist JE, Fagerland MW, Almdahl SM, Hollan I (2016)
Plasma vitamin D levels and inflammation in the aortic wall of patients with coronary artery disease with and without inflammatory rheumatic disease
Scand J Rheumatol, 46 (3), 198-205
DOI 10.3109/03009742.2016.1172664, PubMed 27379927

Palm Ø, Ueland T, Garen T, Michelsen AE, Reiseter S, Aukrust P, Aaløkken TM, Molberg Ø (2016)
Endostatin is higher and associated with pulmonary involvement in primary Sjögren's syndrome
Clin Exp Rheumatol, 34 (4), 690-3
PubMed 27214260

Szodoray P, Stanford SM, Molberg Ø, Munthe LA, Bottini N, Nakken B (2016)
T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity
J Allergy Clin Immunol, 138 (3), 839-851.e8
DOI 10.1016/j.jaci.2016.01.035, PubMed 27056269

Publications 2015

Andersson H, Sem M, Lund MB, Aaløkken TM, Günther A, Walle-Hansen R, Garen T, Molberg Ø (2015)
Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease
Rheumatology (Oxford), 54 (8), 1420-8
DOI 10.1093/rheumatology/kev004, PubMed 25740830

Carmona FD, Mackie SL, Martín JE, Taylor JC, Vaglio A, Eyre S, Bossini-Castillo L, Castañeda S, Cid MC, Hernández-Rodríguez J, Prieto-González S, Solans R, Ramentol-Sintas M, González-Escribano MF, Ortiz-Fernández L, Morado IC, Narváez J, Miranda-Filloy JA, Spanish GCA Group, Beretta L, Lunardi C, Cimmino MA, Gianfreda D, Santilli D, Ramirez GA et al. (2015)
A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility
Am J Hum Genet, 96 (4), 565-80
DOI 10.1016/j.ajhg.2015.02.009, PubMed 25817017

Dobloug GC, Garen T, Brunborg C, Gran JT, Molberg Ø (2015)
Survival and cancer risk in an unselected and complete Norwegian idiopathic inflammatory myopathy cohort
Semin Arthritis Rheum, 45 (3), 301-8
DOI 10.1016/j.semarthrit.2015.06.005, PubMed 26190563

Gunnarsson R, El-Hage F, Aaløkken TM, Reiseter S, Lund MB, Garen T, Norwegian MCTD study group, Molberg Ø (2015)
Associations between anti-Ro52 antibodies and lung fibrosis in mixed connective tissue disease
Rheumatology (Oxford), 55 (1), 103-8
DOI 10.1093/rheumatology/kev300, PubMed 26320136

Hoffmann-Vold AM, Aaløkken TM, Lund MB, Garen T, Midtvedt Ø, Brunborg C, Gran JT, Molberg Ø (2015)
Predictive value of serial high-resolution computed tomography analyses and concurrent lung function tests in systemic sclerosis
Arthritis Rheumatol, 67 (8), 2205-12
DOI 10.1002/art.39166, PubMed 25916462

Reiseter S, Molberg Ø, Gunnarsson R, Lund MB, Aalokken TM, Aukrust P, Ueland T, Garen T, Brunborg C, Michelsen A, Abraityte A, Hoffmann-Vold AM (2015)
Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
Arthritis Res Ther, 17, 231
DOI 10.1186/s13075-015-0756-5, PubMed 26315510

Rothwell S, Cooper RG, Lundberg IE, Miller FW, Gregersen PK, Bowes J, Vencovsky J, Danko K, Limaye V, Selva-O'Callaghan A, Hanna MG, Machado PM, Pachman LM, Reed AM, Rider LG, Cobb J, Platt H, Molberg Ø, Benveniste O, Mathiesen P, Radstake T, Doria A, De Bleecker J, De Paepe B, Maurer B et al. (2015)
Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Ann Rheum Dis, 75 (8), 1558-66
DOI 10.1136/annrheumdis-2015-208119, PubMed 26362759

Publications 2014

Aulie HA, Selvaag AM, Günther A, Lilleby V, Molberg Ø, Hartmann A, Holdaas H, Flatø B (2014)
Arterial haemodynamics and coronary artery calcification in adult patients with juvenile idiopathic arthritis
Ann Rheum Dis, 74 (8), 1515-21
DOI 10.1136/annrheumdis-2013-204804, PubMed 24695010

Dobloug C, Garen T, Bitter H, Stjärne J, Stenseth G, Grøvle L, Sem M, Gran JT, Molberg Ø (2014)
Prevalence and clinical characteristics of adult polymyositis and dermatomyositis; data from a large and unselected Norwegian cohort
Ann Rheum Dis, 74 (8), 1551-6
DOI 10.1136/annrheumdis-2013-205127, PubMed 24695011

Dobloug GC, Antal EA, Sveberg L, Garen T, Bitter H, Stjärne J, Grøvle L, Gran JT, Molberg Ø (2014)
High prevalence of inclusion body myositis in Norway; a population-based clinical epidemiology study
Eur J Neurol, 22 (4), 672-e41
DOI 10.1111/ene.12627, PubMed 25530508

Flåm ST, Gunnarsson R, Garen T, Norwegian MCTD Study Group, Lie BA, Molberg Ø (2014)
The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases
Rheumatology (Oxford), 54 (3), 528-35
DOI 10.1093/rheumatology/keu310, PubMed 25187641

Hoffmann-Vold AM, Gunnarsson R, Garen T, Midtvedt Ø, Molberg Ø (2014)
Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in large, well-defined cohorts of SSc and mixed connective tissue disease
J Rheumatol, 42 (1), 60-3
DOI 10.3899/jrheum.140047, PubMed 25274890

Márquez A, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Fernández-Contreras ME, Ramentol M, Morado IC, Narváez J, Gómez-Vaquero C, Martínez-Taboada VM, Ortego-Centeno N, Sopeña B, Monfort J, García-Villanueva MJ, Caminal-Montero L, de Miguel E, Blanco R, Spanish GCA Consortium, Palm O, Molberg O, Latus J, Braun N, Moosig F, Witte T et al. (2014)
Influence of the IL17A locus in giant cell arteritis susceptibility
Ann Rheum Dis, 73 (9), 1742-5
DOI 10.1136/annrheumdis-2014-205261, PubMed 24919468

Publications 2013

Gunnarsson R, Andreassen AK, Molberg Ø, Lexberg ÅS, Time K, Dhainaut AS, Bertelsen LT, Palm Ø, Irgens K, Becker-Merok A, Nordeide JL, Johnsen V, Pedersen S, Prøven A, Garabet LS, Garen T, Aaløkken TM, Gilboe IM, Gran JT (2013)
Prevalence of pulmonary hypertension in an unselected, mixed connective tissue disease cohort: results of a nationwide, Norwegian cross-sectional multicentre study and review of current literature
Rheumatology (Oxford), 52 (7), 1208-13
DOI 10.1093/rheumatology/kes430, PubMed 23407386

Hoffmann-Vold AM, Molberg Ø, Midtvedt Ø, Garen T, Gran JT (2013)
Survival and causes of death in an unselected and complete cohort of Norwegian patients with systemic sclerosis
J Rheumatol, 40 (7), 1127-33
DOI 10.3899/jrheum.121390, PubMed 23637316

Serrano A, Márquez A, Mackie SL, Carmona FD, Solans R, Miranda-Filloy JA, Hernández-Rodríguez J, Cid MC, Castañeda S, Morado IC, Narváez J, Blanco R, Sopeña B, García-Villanueva MJ, Monfort J, Ortego-Centeno N, Unzurrunzaga A, Marí-Alfonso B, Sánchez Martín J, de Miguel E, Magro C, Raya E, UK GCA Consortium, Spanish GCA Consortium, Braun N et al. (2013)
Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis
Ann Rheum Dis, 72 (11), 1882-1886
DOI 10.1136/annrheumdis-2013-203641, PubMed 23946333

Publications 2012

Dobloug C, Walle-Hansen R, Gran JT, Molberg Ø (2012)
Long-term follow-up of sporadic inclusion body myositis treated with intravenous immunoglobulin: a retrospective study of 16 patients
Clin Exp Rheumatol, 30 (6), 838-42
PubMed 22935197

Gunnarsson R, Aaløkken TM, Molberg Ø, Lund MB, Mynarek GK, Lexberg AS, Time K, Dhainaut AS, Bertelsen LT, Palm O, Irgens K, Becker-Merok A, Nordeide JL, Johnsen V, Pedersen S, Prøven A, Garabet LS, Gran JT (2012)
Prevalence and severity of interstitial lung disease in mixed connective tissue disease: a nationwide, cross-sectional study
Ann Rheum Dis, 71 (12), 1966-72
DOI 10.1136/annrheumdis-2011-201253, PubMed 22550317

Hoffmann-Vold AM, Midtvedt Ø, Molberg Ø, Garen T, Gran JT (2012)
Prevalence of systemic sclerosis in south-east Norway
Rheumatology (Oxford), 51 (9), 1600-5
DOI 10.1093/rheumatology/kes076, PubMed 22539477

Publications 2011

Gunnarsson R, Molberg O, Gilboe IM, Gran JT, PAHNOR1 Study Group (2011)
The prevalence and incidence of mixed connective tissue disease: a national multicentre survey of Norwegian patients
Ann Rheum Dis, 70 (6), 1047-51
DOI 10.1136/ard.2010.143792, PubMed 21398332

Halvorsen EH, Strønen E, Hammer HB, Goll GL, Sollid LM, Molberg O (2011)
Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis
Scand J Immunol, 73 (3), 243-9
DOI 10.1111/j.1365-3083.2010.02498.x, PubMed 21204897

Pollmann S, Stensland M, Halvorsen EH, Sollid LM, Kvien TK, Fleckenstein B, Molberg O (2011)
Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
Rheumatol Int, 32 (5), 1271-6
DOI 10.1007/s00296-010-1765-y, PubMed 21267570

Sem M, Lund MB, Molberg O (2011)
Long-term outcome of lung transplantation in a patient with the anti-synthetase syndrome
Scand J Rheumatol, 40 (4), 327-8
DOI 10.3109/03009742.2011.566280, PubMed 21623666

Publications 2009

Gran JT, Molberg Ø, Dobloug GC, Andersson H, Taraldsrud E, Scheie D (2009)
[Myositis-specific autoantibodies]
Tidsskr Nor Laegeforen, 129 (16), 1631-4
DOI 10.4045/tidsskr.09.35501, PubMed 19721478

Sem M, Molberg O, Lund MB, Gran JT (2009)
Rituximab treatment of the anti-synthetase syndrome: a retrospective case series
Rheumatology (Oxford), 48 (8), 968-71
DOI 10.1093/rheumatology/kep157, PubMed 19531628

Stensland ME, Pollmann S, Molberg Ø, Sollid LM, Fleckenstein B (2009)
Primary sequence, together with other factors, influence peptide deimination by peptidylarginine deiminase-4
Biol Chem, 390 (2), 99-107
DOI 10.1515/BC.2009.019, PubMed 19040354

Publications 2008

Halvorsen EH, Haavardsholm EA, Pollmann S, Boonen A, van der Heijde D, Kvien TK, Molberg Ø (2008)
Serum IgG antibodies to peptidylarginine deiminase 4 predict radiographic progression in patients with rheumatoid arthritis treated with tumour necrosis factor-alpha blocking agents
Ann Rheum Dis, 68 (2), 249-52
DOI 10.1136/ard.2008.094490, PubMed 18723564

Publications 2007

Halvorsen EH, Pollmann S, Gilboe IM, van der Heijde D, Landewé R, Ødegård S, Kvien TK, Molberg Ø (2007)
Serum IgG antibodies to peptidylarginine deiminase 4 in rheumatoid arthritis and associations with disease severity
Ann Rheum Dis, 67 (3), 414-7
DOI 10.1136/ard.2007.080267, PubMed 18006540

Kolltveit KM, Granum S, Aasheim HC, Forsbring M, Sundvold-Gjerstad V, Dai KZ, Molberg O, Schjetne KW, Bogen B, Shapiro VS, Johansen FE, Schenck K, Spurkland A (2007)
Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level
Mol Immunol, 45 (8), 2380-90
DOI 10.1016/j.molimm.2007.11.005, PubMed 18160104

Molberg O (2007)
[Can it be celiac disease?]
Tidsskr Nor Laegeforen, 127 (15), 1952-3
PubMed 17708061

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
DOI 10.1111/j.1365-3083.2006.01881.x, PubMed 17309775

Publications 2006

Molberg Ø, Sollid LM (2006)
A gut feeling for joint inflammation - using coeliac disease to understand rheumatoid arthritis
Trends Immunol, 27 (4), 188-94
DOI 10.1016/j.it.2006.02.006, PubMed 16530013

Ráki M, Tollefsen S, Molberg Ø, Lundin KE, Sollid LM, Jahnsen FL (2006)
A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
Gastroenterology, 131 (2), 428-38
DOI 10.1053/j.gastro.2006.06.002, PubMed 16890596

Tollefsen S, Arentz-Hansen H, Fleckenstein B, Molberg O, Ráki M, Kwok WW, Jung G, Lundin KE, Sollid LM (2006)
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease
J Clin Invest, 116 (8), 2226-36
DOI 10.1172/JCI27620, PubMed 16878175

Publications 2005

Gran JT, Molberg Ø, Midtvedt Ø (2005)
[Pathophysiologic aspects of systemic sclerosis]
Tidsskr Nor Laegeforen, 125 (19), 2622-3
PubMed 16215604

Molberg O, Uhlen AK, Jensen T, Flaete NS, Fleckenstein B, Arentz-Hansen H, Raki M, Lundin KE, Sollid LM (2005)
Mapping of gluten T-cell epitopes in the bread wheat ancestors: implications for celiac disease
Gastroenterology, 128 (2), 393-401
DOI 10.1053/j.gastro.2004.11.003, PubMed 15685550

Qiao SW, Bergseng E, Molberg O, Jung G, Fleckenstein B, Sollid LM (2005)
Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation
J Immunol, 175 (1), 254-61
DOI 10.4049/jimmunol.175.1.254, PubMed 15972656

Qiao SW, Piper J, Haraldsen G, Oynebråten I, Fleckenstein B, Molberg O, Khosla C, Sollid LM (2005)
Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease
J Immunol, 174 (3), 1657-63
DOI 10.4049/jimmunol.174.3.1657, PubMed 15661929

Ráki M, Molberg O, Tollefsen S, Lundin KE, Sollid LM (2005)
The effects of atorvastatin on gluten-induced intestinal T cell responses in coeliac disease
Clin Exp Immunol, 142 (2), 333-40
DOI 10.1111/j.1365-2249.2005.02915.x, PubMed 16232221

Shan L, Qiao SW, Arentz-Hansen H, Molberg Ø, Gray GM, Sollid LM, Khosla C (2005)
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue
J Proteome Res, 4 (5), 1732-41
DOI 10.1021/pr050173t, PubMed 16212427

Publications 2004

Arentz-Hansen H, Fleckenstein B, Molberg Ø, Scott H, Koning F, Jung G, Roepstorff P, Lundin KE, Sollid LM (2004)
The molecular basis for oat intolerance in patients with celiac disease
PLoS Med, 1 (1), e1
DOI 10.1371/journal.pmed.0010001, PubMed 15526039

Marti T, Molberg O, Li Q, Gray GM, Khosla C, Sollid LM (2004)
Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization
J Pharmacol Exp Ther, 312 (1), 19-26
DOI 10.1124/jpet.104.073312, PubMed 15358813

Qiao SW, Bergseng E, Molberg Ø, Xia J, Fleckenstein B, Khosla C, Sollid LM (2004)
Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion
J Immunol, 173 (3), 1757-62
DOI 10.4049/jimmunol.173.3.1757, PubMed 15265905

Publications 2003

Molberg Ø, Solheim Flaete N, Jensen T, Lundin KE, Arentz-Hansen H, Anderson OD, Kjersti Uhlen A, Sollid LM (2003)
Intestinal T-cell responses to high-molecular-weight glutenins in celiac disease
Gastroenterology, 125 (2), 337-44
DOI 10.1016/s0016-5085(03)00890-4, PubMed 12891534

Shan L, Molberg O, Gray GM, Sollid LM, Khosla C (2003)
Gluten peptides and celiac disease - Response
Science, 299 (5606), 513-514

Sollid LM, Arentz-Hansen H, Fleckenstein B, Lundin KEA, McAdam S, Molberg O, Qiao SW, Quarsten H (2003)
The T cell response to gluten and control of coeliac disease development
COELIAC DISEASE, 71-76

Publications 2002

Arentz-Hansen H, McAdam SN, Molberg Ø, Fleckenstein B, Lundin KE, Jørgensen TJ, Jung G, Roepstorff P, Sollid LM (2002)
Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
Gastroenterology, 123 (3), 803-9
DOI 10.1053/gast.2002.35381, PubMed 12198706

Fleckenstein B, Molberg Ø, Qiao SW, Schmid DG, von der Mülbe F, Elgstøen K, Jung G, Sollid LM (2002)
Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
J Biol Chem, 277 (37), 34109-16
DOI 10.1074/jbc.M204521200, PubMed 12093810

Shan L, Molberg Ø, Parrot I, Hausch F, Filiz F, Gray GM, Sollid LM, Khosla C (2002)
Structural basis for gluten intolerance in celiac sprue
Science, 297 (5590), 2275-9
DOI 10.1126/science.1074129, PubMed 12351792

Publications 2001

Molberg O, McAdam S, Lundin KE, Kristiansen C, Arentz-Hansen H, Kett K, Sollid LM (2001)
T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase
Eur J Immunol, 31 (5), 1317-23
DOI 10.1002/1521-4141(200105)31:5<1317::AID-IMMU1317>3.0.CO;2-I, PubMed 11465088

Sollid LM, McAdam SN, Molberg O, Quarsten H, Arentz-Hansen H, Louka AS, Lundin KE (2001)
Genes and environment in celiac disease
Acta Odontol Scand, 59 (3), 183-6
DOI 10.1080/000163501750266792, PubMed 11501889

Publications 2000

Arentz-Hansen EH, McAdam SN, Molberg O, Kristiansen C, Sollid LM (2000)
Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease
Gut, 46 (1), 46-51
DOI 10.1136/gut.46.1.46, PubMed 10601054

Arentz-Hansen H, Körner R, Molberg O, Quarsten H, Vader W, Kooy YM, Lundin KE, Koning F, Roepstorff P, Sollid LM, McAdam SN (2000)
The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
J Exp Med, 191 (4), 603-12
DOI 10.1084/jem.191.4.603, PubMed 10684852

Molberg O, McAdam SN, Lundin KE, Sollid LM (2000)
Studies of gliadin-specific T-cells in celiac disease
Methods Mol Med, 41, 105-24
DOI 10.1385/1-59259-082-9:105, PubMed 21374436

Molberg O, McAdam SN, Sollid LM (2000)
Role of tissue transglutaminase in celiac disease
J Pediatr Gastroenterol Nutr, 30 (3), 232-40
DOI 10.1097/00005176-200003000-00005, PubMed 10749404

Publications 1999

Quarsten H, Molberg O, Fugger L, McAdam SN, Sollid LM (1999)
HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
Eur J Immunol, 29 (8), 2506-14
DOI 10.1002/(SICI)1521-4141(199908)29:08<2506::AID-IMMU2506>3.0.CO;2-9, PubMed 10458765

Publications 1998

Molberg Ø (1998)
T cells of the human small intestinal mucosa: studies of HLA restriction and antigen-specificity with particular reference to coeliac disease
Institute of Transplantation Immunology, Department Groupof Laboratory Medicine, Rikshospitalet, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 98239117x, ISBN 82-7633-110-6

Molberg O, Lundin KE, Nilsen EM, Scott H, Kett K, Brandtzaeg P, Thorsby E, Sollid LM (1998)
HLA restriction patterns of gliadin- and astrovirus-specific CD4+ T cells isolated in parallel from the small intestine of celiac disease patients
Tissue Antigens, 52 (5), 407-15
DOI 10.1111/j.1399-0039.1998.tb03066.x, PubMed 9864029

Molberg O, Mcadam SN, Körner R, Quarsten H, Kristiansen C, Madsen L, Fugger L, Scott H, Norén O, Roepstorff P, Lundin KE, Sjöström H, Sollid LM (1998)
Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
Nat Med, 4 (6), 713-7
DOI 10.1038/nm0698-713, PubMed 9623982

Molberg O, Nilsen EM, Sollid LM, Scott H, Brandtzaeg P, Thorsby E, Lundin KE (1998)
CD4+ T cells with specific reactivity against astrovirus isolated from normal human small intestine
Gastroenterology, 114 (1), 115-22
DOI 10.1016/s0016-5085(98)70639-0, PubMed 9428225

Sjöström H, Lundin KE, Molberg O, Körner R, McAdam SN, Anthonsen D, Quarsten H, Norén O, Roepstorff P, Thorsby E, Sollid LM (1998)
Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition
Scand J Immunol, 48 (2), 111-5
DOI 10.1046/j.1365-3083.1998.00397.x, PubMed 9716100

van de Wal Y, Kooy YM, van Veelen PA, Peña SA, Mearin LM, Molberg O, Lundin KE, Sollid LM, Mutis T, Benckhuijsen WE, Drijfhout JW, Koning F (1998)
Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin
Proc Natl Acad Sci U S A, 95 (17), 10050-4
DOI 10.1073/pnas.95.17.10050, PubMed 9707598

Publications 1997

Lundin KE, Sollid LM, Anthonsen D, Norén O, Molberg O, Thorsby E, Sjöström H (1997)
Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease
Gastroenterology, 112 (3), 752-9
DOI 10.1053/gast.1997.v112.pm9041236, PubMed 9041236

Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
Scand J Immunol, 46 (3), 103-9
DOI 10.1046/j.1365-3083.1997.d01-93.x, PubMed 9315123

Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KE (1997)
Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
Scand J Immunol, 46 (1), 103-8
PubMed 9246215

Molberg O, Kett K, Scott H, Thorsby E, Sollid LM, Lundin KEA (1997)
Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls (vol 46, pg 103, 1997)
Scand. J. Immunol., 46 (3), 317-+

Scott H, Nilsen E, Sollid LM, Lundin KE, Rugtveit J, Molberg O, Thorsby E, Brandtzaeg P (1997)
Immunopathology of gluten-sensitive enteropathy
Springer Semin Immunopathol, 18 (4), 535-53
DOI 10.1007/BF00824057, PubMed 9144869

Sollid LM, Johansen BH, Lundin KEA, Molberg O, Scott H, Sjostrom H, Thorpe CJ, Vartdal F, Thorsby E (1997)
The molecular basis of the HLA association in celiac disease: A model for other HLA-associated diseases
ALFRED BENZON SYMP S, 40, 362-377

Sollid LM, Johansen BH, Lundin KEA, Molberg O, Scott H, Vartdal F, Thorsby E (1997)
The molecular basis of the HLA association in celiac disease - A model disease for type 1 diabetes and other HLA associated diseases
NATO ASI 3 HIGH TECH, 35, 61-69

Sollid LM, Lundin KEA, Sjostrom H, Molberg O, Thorsby E (1997)
HLA-DQ molecules, peptides and T cells in coeliac disease
COELIAC DISEASE, 265-274

Sollid LM, Molberg O, McAdam S, Lundin KE (1997)
Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?
Gut, 41 (6), 851-2
DOI 10.1136/gut.41.6.851, PubMed 9462222