Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2017 from OUS - Department of Cardiology B (Div Med)
77 publications found
Early discharge compared with ordinary discharge after percutaneous coronary intervention - a systematic review and meta-analysis of safety and cost
Vasc Health Risk Manag, 13, 101-109
DOI 10.2147/VHRM.S122951, PubMed 28356750
ESC working group position paper on myocardial infarction with non-obstructive coronary arteries
Eur Heart J, 38 (3), 143-153
DOI 10.1093/eurheartj/ehw149, PubMed 28158518
Heart rate prediction of outcome in heart failure following myocardial infarction depend on heart rhythm status an analysis from the high-risk myocardial infarction database initiative
Int J Cardiol, 249, 274-281
DOI 10.1016/j.ijcard.2017.09.182, PubMed 28964557
Appropriateness of anteroseptal myocardial infarction nomenclature evaluated by late gadolinium enhancement cardiovascular magnetic resonance imaging
J Electrocardiol, 51 (2), 218-223
DOI 10.1016/j.jelectrocard.2017.09.013, PubMed 29103621
Antihypertensive Treatment With β-Blockade in Patients With Asymptomatic Aortic Stenosis and Association With Cardiovascular Events
J Am Heart Assoc, 6 (12)
DOI 10.1161/JAHA.117.006709, PubMed 29180457
Thrombolytic Treatment for Ischaemic Stroke: Could the Crisis of Confidence Have Been Avoided by Better Analysis of Trial Data?
Drugs Aging, 34 (2), 79-88
DOI 10.1007/s40266-016-0432-8, PubMed 28120326
Procoagulant activity in patients with combined type 2 diabetes and coronary artery disease: No effects of long-term exercise training
Diab Vasc Dis Res, 14 (2), 144-151
DOI 10.1177/1479164116679080, PubMed 28111966
Plasma biomarker levels and non-obstructive coronary artery disease determined by coronary computed tomography angiography
Clin Physiol Funct Imaging, 38 (2), 246-253
DOI 10.1111/cpf.12407, PubMed 28168796
Administration of the Mitochondrial Permeability Transition Pore Inhibitor, TRO40303, prior to Primary Percutaneous Coronary Intervention, Does Not Affect the Levels of Pro-Inflammatory Cytokines or Acute-Phase Proteins
Cardiology, 138 (2), 122-132
DOI 10.1159/000475460, PubMed 28651249
Reduced endothelial activation after exercise is associated with improved HbA1c in patients with type 2 diabetes and coronary artery disease
Diab Vasc Dis Res, 14 (2), 94-103
DOI 10.1177/1479164116679077, PubMed 28111980
Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials
Int J Cardiol, 244, 59-66
DOI 10.1016/j.ijcard.2017.06.040, PubMed 28634037
Platelet-, monocyte-derived and tissue factor-carrying circulating microparticles are related to acute myocardial infarction severity
PLoS One, 12 (2), e0172558
DOI 10.1371/journal.pone.0172558, PubMed 28207887
Pro-coagulant activity during exercise testing in patients with coronary artery disease
Thromb J, 15, 3
DOI 10.1186/s12959-016-0127-8, PubMed 28115916
Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
PLoS One, 12 (2), e0169830
DOI 10.1371/journal.pone.0169830, PubMed 28225768
Methotrexate and anti-tumor necrosis factor treatment improves endothelial function in patients with inflammatory arthritis
Arthritis Res Ther, 19 (1), 232
DOI 10.1186/s13075-017-1439-1, PubMed 29041979
Biomarkers of endothelial activation and thrombosis in tunnel construction workers exposed to airborne contaminants
Int Arch Occup Environ Health, 90 (4), 309-317
DOI 10.1007/s00420-017-1199-x, PubMed 28124139
Sham or no sham control: that is the question in trials of renal denervation for resistant hypertension. A systematic meta-analysis
Blood Press, 26 (4), 195-203
DOI 10.1080/08037051.2017.1311769, PubMed 28443356
Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction
J Electrocardiol, 51 (2), 195-202
DOI 10.1016/j.jelectrocard.2017.11.002, PubMed 29174706
Statins attenuate but do not eliminate the reverse epidemiology of total serum cholesterol in patients with non-ischemic chronic heart failure
Int J Cardiol, 238, 97-104
DOI 10.1016/j.ijcard.2017.03.028, PubMed 28342630
Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure
Clin Res Cardiol, 106 (9), 711-721
DOI 10.1007/s00392-017-1115-0, PubMed 28434020
Changes in dietary pattern when including 700 g of salmon per week to patients with atherosclerotic heart disease
Clin. Nutr. ESPEN, 19, 38-44
Winston Churchill - Life story
Tidsskr. Nor. Laegeforen., 137 (14-15), 1065-1067
Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study
J Am Heart Assoc, 6 (11)
DOI 10.1161/JAHA.117.006513, PubMed 29118031
Effects of Vitamin D Supplementation on Insulin Sensitivity and Insulin Secretion in Subjects With Type 2 Diabetes and Vitamin D Deficiency: A Randomized Controlled Trial
Diabetes Care, 40 (7), 872-878
DOI 10.2337/dc16-2302, PubMed 28468770
Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
BMC Infect Dis, 17 (1), 445
DOI 10.1186/s12879-017-2547-x, PubMed 28645263
Management of antithrombotic therapy after bleeding in patients with coronary artery disease and/or atrial fibrillation: expert consensus paper of the European Society of Cardiology Working Group on Thrombosis
Eur Heart J, 38 (19), 1455-1462
DOI 10.1093/eurheartj/ehw454, PubMed 27789570
Reduced HDL function in children and young adults with type 1 diabetes
Cardiovasc Diabetol, 16 (1), 85
DOI 10.1186/s12933-017-0570-2, PubMed 28683835
Effect of sinus rhythm restoration on markers of thrombin generation in atrial fibrillation
Thromb J, 15, 30
DOI 10.1186/s12959-017-0153-1, PubMed 29299030
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation
BMC Infect Dis, 17 (1), 234
DOI 10.1186/s12879-017-2334-8, PubMed 28356058
Systolic mitral annulus velocity is a sensitive index for changes in left ventricular systolic function during inotropic therapy in patients with acute heart failure
Eur Heart J Acute Cardiovasc Care, 7 (4), 321-329
DOI 10.1177/2048872616687114, PubMed 28045338
2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
Rev Esp Cardiol (Engl Ed), 70 (12), 1082
DOI 10.1016/j.rec.2017.11.010, PubMed 29198432
Results of a randomized controlled pilot trial of intravascular renal denervation for management of treatment-resistant hypertension
Blood Press, 26 (6), 321-331
DOI 10.1080/08037051.2017.1320939, PubMed 28489464
Hypertension and cardiovascular risk: General aspects
Pharmacol Res, 129, 95-99
DOI 10.1016/j.phrs.2017.11.003, PubMed 29127059
The Un-Observed Automated Office Blood Pressure Measurement Technique Used in the SPRINT Study Points to a Standard Target Office Systolic Blood Pressure <140 mmHg
Curr Hypertens Rep, 19 (1), 3
DOI 10.1007/s11906-017-0700-y, PubMed 28091868
A critical review of the systolic blood pressure intervention trial (SPRINT)
Eur. Heart J., 38 (44), 3260-3265
New guidelines for the prevention of cardiovascular disease
Tidsskr. Nor. Laegeforen., 137 (16), 1164-1168
Percutaneous coronary intervention and antiplatelet therapy in patients with atrial fibrillation receiving apixaban or warfarin: Insights from the ARISTOTLE trial
Am Heart J, 197, 133-141
DOI 10.1016/j.ahj.2017.11.005, PubMed 29447773
Heart Rate and Rhythm and the Benefit of Beta-Blockers in Patients With Heart Failure
J Am Coll Cardiol, 69 (24), 2885-2896
DOI 10.1016/j.jacc.2017.04.001, PubMed 28467883
Long-term survival in patients with acute myocardial infarction and out-of-hospital cardiac arrest: A prospective cohort study
Resuscitation, 122, 41-47
DOI 10.1016/j.resuscitation.2017.11.047, PubMed 29155294
Gender differences in all-cause, cardiovascular and cancer mortality during long-term follow-up after acute myocardial infarction; a prospective cohort study
BMC Cardiovasc Disord, 17 (1), 75
DOI 10.1186/s12872-017-0508-3, PubMed 28288586
Galectin-3, a marker of cardiac remodeling, is inversely related to serum levels of marine omega-3 fatty acids. A cross-sectional study
JRSM Cardiovasc Dis, 6, 2048004017729984
DOI 10.1177/2048004017729984, PubMed 28932392
Mechanisms of ECG signs in chronic obstructive pulmonary disease
Open Heart, 4 (1), e000552
DOI 10.1136/openhrt-2016-000552, PubMed 28533915
Enlarged perivascular spaces are associated with health-related quality of life in patients with acute ischemic stroke
CNS Neurosci Ther, 23 (12), 973-979
DOI 10.1111/cns.12766, PubMed 29052954
Determining the impact of 24/7 phone support on hospital readmissions after aortic valve replacement surgery (the AVRre study): study protocol for a randomised controlled trial
Trials, 18 (1), 246
DOI 10.1186/s13063-017-1971-y, PubMed 28693599
Impact of stroke volume on cardiovascular risk during progression of aortic valve stenosis
Heart, 103 (18), 1443-1448
DOI 10.1136/heartjnl-2016-310917, PubMed 28455295
Automatic identification of variables in epidemiological datasets using logic regression
BMC Med Inform Decis Mak, 17 (1), 40
DOI 10.1186/s12911-017-0429-1, PubMed 28407816
From 'essential' hypertension to intensive blood pressure lowering: the pros and cons of lower target values
Eur Heart J, 38 (44), 3258-3271
DOI 10.1093/eurheartj/ehx643, PubMed 29177419
Immune markers, diurnal blood pressure profile and cardiac function in virologically suppressed HIV-infected patients
Blood Press, 26 (6), 332-340
DOI 10.1080/08037051.2017.1346459, PubMed 28675304
Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men
Blood Press, 26 (4), 229-236
DOI 10.1080/08037051.2017.1291276, PubMed 28276720
Apparent treatment-resistant hypertension - patient-physician relationship and ethical issues
Blood Press, 26 (3), 133-138
DOI 10.1080/08037051.2016.1277129, PubMed 28078909
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur J Pharmacol, 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363
A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease
Mediators Inflamm, 2017, 5380638
DOI 10.1155/2017/5380638, PubMed 28596642
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
MMP-9 and Its Regulators TIMP-1 and EMMPRIN in Patients with Acute ST-Elevation Myocardial Infarction: A NORDISTEMI Substudy
Cardiology, 139 (1), 17-24
DOI 10.1159/000481684, PubMed 29141241
Secondary Prevention of Cardiovascular Disease in Patients With Type 2 Diabetes Mellitus: International Insights From the TECOS Trial (Trial Evaluating Cardiovascular Outcomes With Sitagliptin)
Circulation, 136 (13), 1193-1203
DOI 10.1161/CIRCULATIONAHA.117.027252, PubMed 28626088
Changes in oral anticoagulation for elective cardioversion: results from a European cardioversion registry
Eur Heart J Cardiovasc Pharmacother, 3 (3), 147-150
DOI 10.1093/ehjcvp/pvx003, PubMed 28329309
Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis
J Am Coll Cardiol, 70 (14), 1760-1776
DOI 10.1016/j.jacc.2017.08.037, PubMed 28958334
Long-term predictors of stroke in healthy middle-aged men
Int J Stroke, 13 (3), 292-300
DOI 10.1177/1747493017730760, PubMed 28929941
Evaluation of circulating levels of CCN2/connective tissue growth factor in patients with ST-elevation myocardial infarction
Sci Rep, 7 (1), 11945
DOI 10.1038/s41598-017-12372-w, PubMed 28931920
Heart failure with preserved ejection fraction
Tidsskr. Nor. Laegeforen., 137 (18), 1426-1431
Heart failure with preserved ejection fraction
Tidsskr Nor Laegeforen, 137 (18)
DOI 10.4045/tidsskr.16.1068, PubMed 28972354
Does renal function affect the efficacy or safety of a pharmacoinvasive strategy in patients with ST-elevation myocardial infarction? A meta-analysis
Am Heart J, 193, 46-54
DOI 10.1016/j.ahj.2017.07.015, PubMed 29129254
Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography
Eur Radiol, 27 (9), 3934-3941
DOI 10.1007/s00330-017-4770-7, PubMed 28271154
Time-resolved tracking of the atrioventricular plane displacement in Cardiovascular Magnetic Resonance (CMR) images
BMC Med Imaging, 17 (1), 19
DOI 10.1186/s12880-017-0189-5, PubMed 28241751
Myocardium at risk assessed by electrocardiographic scores and cardiovascular magnetic resonance - a MITOCARE substudy
J Electrocardiol, 50 (6), 725-731
DOI 10.1016/j.jelectrocard.2017.08.019, PubMed 28918213
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034, PubMed 28253327
Cardiopulmonary exercise test and PaO2 in evaluation of pulmonary hypertension in COPD
Int J Chron Obstruct Pulmon Dis, 13, 91-100
DOI 10.2147/COPD.S150034, PubMed 29339921
Spironolactone Treatment and Effect on Survival in Chronic Heart Failure Patients with Reduced Renal Function: A Propensity-Matched Study
Cardiorenal Med, 7 (2), 128-136
DOI 10.1159/000454933, PubMed 28611786
Gender differences in the effects of cardiovascular drugs
Eur Heart J Cardiovasc Pharmacother, 3 (3), 163-182
DOI 10.1093/ehjcvp/pvw042, PubMed 28329228
Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin
Stroke, 48 (12), 3266-3273
DOI 10.1161/STROKEAHA.117.017574, PubMed 29089455
Neurohormonal Blockade in Heart Failure
Card Fail Rev, 3 (1), 19-24
DOI 10.15420/cfr.2016:22:2, PubMed 28785471
Comprehensive efforts to increase adherence to statin therapy
Eur Heart J, 38 (32), 2473-2479
DOI 10.1093/eurheartj/ehw628, PubMed 28077470
vWF/ADAMTS13 is associated with on-aspirin residual platelet reactivity and clinical outcome in patients with stable coronary artery disease
Thromb J, 15, 28
DOI 10.1186/s12959-017-0151-3, PubMed 29200971
Thrombin Generation in Patients With Suspected Venous Thromboembolism
Clin Appl Thromb Hemost, 23 (5), 416-421
DOI 10.1177/1076029617700999, PubMed 28335612
Continuing or Temporarily Stopping Prestroke Antihypertensive Medication in Acute Stroke: An Individual Patient Data Meta-Analysis
Hypertension, 69 (5), 933-941
DOI 10.1161/HYPERTENSIONAHA.116.07982, PubMed 28264916
Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial
Transl Stroke Res, 9 (2), 120-129
DOI 10.1007/s12975-017-0548-0, PubMed 28770403