Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2021 from OUS - Department of Acute Medicine

33 publications found

Aarskog NR, Aass HC, Holter JC, Rostrup M, Holten AR (2021)
Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?
Crit Care Explor, 3 (10), e0542
DOI 10.1097/CCE.0000000000000542, PubMed 34604785

Amundsen EK, Binde C, Christensen EE, Klingenberg O, Kvale D, Holten AR (2021)
Prognostic Value of Nucleated RBCs for Patients With Suspected Sepsis in the Emergency Department: A Single-Center Prospective Cohort Study
Crit Care Explor, 3 (7), e0490
DOI 10.1097/CCE.0000000000000490, PubMed 34291222

Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903

Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Hypertension, 78 (3), 617-628
DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336

Bonsaksen T, Ekeberg Ø, Schou-Bredal I, Skogstad L, Heir T, Grimholt TK (2021)
Use of Alcohol and Addictive Drugs During the COVID-19 Outbreak in Norway: Associations With Mental Health and Pandemic-Related Problems
Front Public Health, 9, 667729
DOI 10.3389/fpubh.2021.667729, PubMed 34195169

Bonsaksen T, Skogstad L, Heir T, Ekeberg Ø, Schou-Bredal I, Grimholt TK (2021)
Suicide Thoughts and Attempts in the Norwegian General Population during the Early Stage of the COVID-19 Outbreak
Int J Environ Res Public Health, 18 (8)
DOI 10.3390/ijerph18084102, PubMed 33924558

Borud EK, Nakstad ER, Håberg SE, Lind A, Fadum EA, Taxt AM, Steens A, Gjein GE, Sunde MW, Iversen P, Svanevik M, Ahmad BM, Waldow T, Norheim AJ (2021)
Severe acute respiratory syndrome coronavirus 2 prevalence in 1170 asymptomatic Norwegian conscripts
Health Sci Rep, 4 (1), e233
DOI 10.1002/hsr2.233, PubMed 33490637

Carr E, Bendayan R, Bean D, Stammers M, Wang W, Zhang H, Searle T, Kraljevic Z, Shek A, Phan HTT, Muruet W, Gupta RK, Shinton AJ, Wyatt M, Shi T, Zhang X, Pickles A, Stahl D, Zakeri R, Noursadeghi M, O'Gallagher K, Rogers M, Folarin A, Karwath A, Wickstrøm KE et al. (2021)
Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study
BMC Med, 19 (1), 23
DOI 10.1186/s12916-020-01893-3, PubMed 33472631

Chaban V, Nakstad ER, Stær-Jensen H, Schjalm C, Seljeflot I, Vaage J, Lundqvist C, Benth JŠ, Sunde K, Mollnes TE, Andersen GØ, Pischke SE (2021)
Complement activation is associated with poor outcome after out-of-hospital cardiac arrest
Resuscitation, 166, 129-136
DOI 10.1016/j.resuscitation.2021.05.038, PubMed 34126135

Christensen EE, Jørgensen MJ, Nore KG, Dahl TB, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter JC, Holten AR, Halvorsen B, Dyrhol-Riise AM (2021)
Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns
J Intern Med, 290 (3), 677-692
DOI 10.1111/joim.13310, PubMed 34080738

Engebretsen S, Bogstrand ST, Jacobsen D, Rimstad R (2021)
Quality of care, resource use and patient outcome by use of emergency response team compared with standard care for critically ill medical patients in the emergency department: a retrospective single-centre cohort study from Norway
BMJ Open, 11 (8), e047264
DOI 10.1136/bmjopen-2020-047264, PubMed 34385247

Hovda KE, Lao YE, Gadeholt G, Jacobsen D (2021)
Formate test for bedside diagnosis of methanol poisoning
Basic Clin Pharmacol Toxicol, 129 (1), 86-88
DOI 10.1111/bcpt.13597, PubMed 33915025

Langberg C, Hadley CL, Midtervoll M, Edvardsen HME, Molden E, Shafiei M, Jacobsen D (2021)
Quetiapine Poisoning - Epidemiology, Toxicokinetics and Review of the Literature
Lupine Online Journal of Medical Sciences, 5 (5), 565-573
PublikaID 372

Lao YE, Goffeng A, Spillum BJ, Jacobsen D, Nakstad ER, Hovda KE (2021)
A survey of the antidote preparedness in Norwegian hospitals
Eur J Hosp Pharm (in press)
DOI 10.1136/ejhpharm-2020-002544, PubMed 33483361

Lao YE, Vartdal T, Froeyshov S, Latimer B, Kvaerner C, Mataric M, Holm P, Foreid S, Jacobsen D, McMartin K, Hovda KE (2021)
Fomepizole dosing during continuous renal replacement therapy - an observational study
Clin Toxicol (Phila)
DOI 10.1080/15563650.2021.1980581, PubMed 34585641

Lie I, Stafseth S, Skogstad L, Hovland IS, Hovde H, Ekeberg Ø, Ræder J (2021)
Healthcare professionals in COVID-19-intensive care units in Norway: preparedness and working conditions: a cohort study
BMJ Open, 11 (10), e049135
DOI 10.1136/bmjopen-2021-049135, PubMed 34635518

Midtlyng L, Høiseth G, Luytkis H, Kristoffersen L, Le Nygaard I, Strand MC, Arnestad M, Vevelstad M (2021)
Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death
Forensic Sci Int, 321, 110726
DOI 10.1016/j.forsciint.2021.110726, PubMed 33631622

Miró Ò, Waring WS, Dargan PI, Wood DM, Dines AM, Yates C, Giraudon I, Moughty A, O'Connor N, Heyerdahl F, Hovda KE, Vallersnes OM, Paasma R, Pold K, Jürgens G, Megarbane B, Anand JS, Liakoni E, Liechti M, Eyer F, Zacharov S, Caganova B, Bonnici J, Radenkova-Saeva J, Galicia M et al. (2021)
Variation of drugs involved in acute drug toxicity presentations based on age and sex: an epidemiological approach based on European emergency departments
Clin Toxicol (Phila), 59 (10), 896-904
DOI 10.1080/15563650.2021.1884693, PubMed 33724118

Nydal SM, Munyaw Y, Bruun JN, Brantsæter AB (2021)
Achievements and Challenges in the Prevention of Mother-to-Child Transmission of HIV-A Retrospective Cohort Study from a Rural Hospital in Northern Tanzania
Int J Environ Res Public Health, 18 (5)
DOI 10.3390/ijerph18052751, PubMed 33803114

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890

Persett PS, Ekeberg Ø, Jacobsen D, Bjornaas MA, Myhren H (2021)
Higher Suicide Intent in Patients Attempting Suicide With Violent Methods Versus Self-Poisoning
Crisis, 1-8 (in press)
DOI 10.1027/0227-5910/a000773, PubMed 33890826

Schou-Bredal I, Grimholt T, Bonsaksen T, Skogstad L, Heir T, Ekeberg O (2021)
Optimists' and pessimists' self-reported mental and global health during the COVID-19 pandemic in Norway
HEALTH PSYCHOL. REP., 9 (2), 160-168
DOI 10.5114/hpr.2021.102394

Schou-Bredal I, Grimholt TK, Bonsaksen T, Skogstad L, Heir T, Ekeberg Ø (2021)
Psychological responses and associated factors during the initial lockdown due to the corona disease epidemic (COVID-19) among Norwegian citizens
J Ment Health
DOI 10.1080/09638237.2021.1952949, PubMed 34309479

Schou-Bredal I, Skogstad L, Grimholt TK, Bonsaksen T, Ekeberg Ø, Heir T (2021)
Concerns in the Norwegian Population during the Initial Lockdown Due to the COVID-19 Pandemic
Int J Environ Res Public Health, 18 (11)
DOI 10.3390/ijerph18116119, PubMed 34204043

Skogstad L, Schou-Bredal I, Bonsaksen T, Heir T, Ekeberg Ø, Grimholt T (2021)
Concerns Related to the COVID-19 in Adult Norwegians during the First Outbreak in 2020: A Qualitative Approach
Int J Environ Res Public Health, 18 (8)
DOI 10.3390/ijerph18084312, PubMed 33921705

Styrvold M, Grimholt TK (2021)
The Role of General Practitioners in Suicide Prevention-What You Said and Did then Actually Saved My Life
Reports, 4 (3), 23
DOI 10.3390/reports4030023

Tran JV, Brekke M, Vallersnes OM (2021)
Poisonings by substances of abuse at the Oslo Accident and Emergency Outpatient Clinic 2014-18
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.20.0751, PubMed 33950661

Undrum Bergland O, Larstorp ACK, Lund Søraas C, Høieggen A, Rostrup M, Norheim Kjaer V, Godang K, Sevre K, Fadl Elmula FEM (2021)
Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study
Blood Press, 30 (3), 154-164
DOI 10.1080/08037051.2020.1868286, PubMed 33399016

Vibeto JH, Vallersnes OM, Dobloug A, Brekke M, Jacobsen D, Ekeberg Ø, Wangen KR (2021)
Treating patients with opioid overdose at a primary care emergency outpatient clinic: a cost-minimization analysis
Cost Eff Resour Alloc, 19 (1), 48
DOI 10.1186/s12962-021-00303-6, PubMed 34348747

Waldman W, Kabata PM, Dines AM, Wood DM, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Euro-DEN Research Group, Dargan PI, Sein Anand J (2021)
Rhabdomyolysis related to acute recreational drug toxicity-A Euro-DEN study
PLoS One, 16 (3), e0246297
DOI 10.1371/journal.pone.0246297, PubMed 33705425

Wickstrøm KE, Vitelli V, Carr E, Holten AR, Bendayan R, Reiner AH, Bean D, Searle T, Shek A, Kraljevic Z, Teo J, Dobson R, Tonby K, Köhn-Luque A, Amundsen EK (2021)
Regional performance variation in external validation of four prediction models for severity of COVID-19 at hospital admission: An observational multi-centre cohort study
PLoS One, 16 (8), e0255748
DOI 10.1371/journal.pone.0255748, PubMed 34432797

Wimmer H, Lundqvist C, Šaltytė Benth J, Stavem K, Andersen GØ, Henriksen J, Drægni T, Sunde K, Nakstad ER (2021)
Health-related quality of life after out-of-hospital cardiac arrest - a five-year follow-up studyJūratė Šaltytė Benth
Resuscitation, 162, 372-380
DOI 10.1016/j.resuscitation.2021.01.036, PubMed 33571604

 
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