
Lene Wierød
- Head engineer
Publications 2019
Inhibitors of AKT kinase increase LDL receptor mRNA expression by two different mechanisms
PLoS One, 14 (6), e0218537
DOI 10.1371/journal.pone.0218537, PubMed 31216345
Publications 2018
Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNA
Sci Rep, 8 (1), 16174
DOI 10.1038/s41598-018-34237-6, PubMed 30385871
Publications 2017
Prevalence of cholesteryl ester storage disease among hypercholesterolemic subjects and functional characterization of mutations in the lysosomal acid lipase gene
Mol Genet Metab, 123 (2), 169-176
DOI 10.1016/j.ymgme.2017.11.008, PubMed 29196158
Publications 2016
Studies of the autoinhibitory segment comprising residues 31-60 of the prodomain of PCSK9: Possible implications for the mechanism underlying gain-of-function mutations
Mol Genet Metab Rep, 9, 86-93
DOI 10.1016/j.ymgmr.2016.11.003, PubMed 27896130
Publications 2013
FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
J Cell Physiol, 228 (6), 1304-13
DOI 10.1002/jcp.24287, PubMed 23168795
EGF activates autocrine TGFα to induce prolonged egf receptor signaling and hepatocyte proliferation
Cell Physiol Biochem, 32 (3), 511-22
DOI 10.1159/000354454, PubMed 24008581
Publications 2012
RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver
J Surg Oncol, 107 (4), 393-401
DOI 10.1002/jso.23224, PubMed 22927239
Publications 2011
EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase
J Cell Physiol, 226 (9), 2267-78
DOI 10.1002/jcp.22563, PubMed 21660950
Publications 2008
Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K
J Cell Physiol, 215 (3), 818-26
DOI 10.1002/jcp.21367, PubMed 18163378
Publications 2007
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
FASEB J, 22 (2), 466-76
DOI 10.1096/fj.07-8650com, PubMed 17928366
Regulation of cell cycle progression and cellular survival in primary rat hepatocytes
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 525, 1 b. (flere pag.)
BIBSYS 070884137, ISBN 978-82-8072-704-6
Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes
Oncogene, 27 (19), 2763-71
DOI 10.1038/sj.onc.1210937, PubMed 18026139
CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes
Cell Prolif, 40 (4), 475-87
DOI 10.1111/j.1365-2184.2007.00451.x, PubMed 17635516
Publications 2005
Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes
Hepatology, 42 (1), 200-7
DOI 10.1002/hep.20762, PubMed 15962331
Publications 2001
Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
Eur J Cell Biol, 80 (4), 285-94
DOI 10.1078/0171-9335-00160, PubMed 11370743
Saponin permeabilization of rough microsomes from rat liver reveals a novel prothrombin pool
Biochim Biophys Acta, 1526 (3), 249-56
DOI 10.1016/s0304-4165(01)00137-4, PubMed 11410334
Publications 1999
[Why is dioxin harmful?]
Tidsskr Nor Laegeforen, 119 (29), 4323-8
PubMed 10667131
Alteration of G1 cell-cycle protein expression and induction of p53 but not p21/waf1 by the DNA-modifying carcinogen 2-acetylaminofluorene in growth-stimulated hepatocytes in vitro
Mol Carcinog, 24 (1), 36-46
DOI 10.1002/(sici)1098-2744(199901)24:1<36::aid-mc6>3.0.co;2-i, PubMed 10029409
Publications 1996
En undersøkelse over membranassosiering, karakterisering og karboksylering av protrombin i endoplasmatisk retikulum
L. Wierød, Oslo, 113 s.
BIBSYS 960897097