Elisabeth Larsen

  • Postdoc Ph.D
  • +47 23073119

Publications 2016

Ougland R, Jonson I, Moen MN, Nesse G, Asker G, Klungland A, Larsen E (2016)
Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells
Cell Physiol Biochem, 38 (1), 173-84
DOI 10.1159/000438619, PubMed 26765775

Publications 2015

Ougland R, Rognes T, Klungland A, Larsen E (2015)
Non-homologous functions of the AlkB homologs
J Mol Cell Biol, 7 (6), 494-504
DOI 10.1093/jmcb/mjv029, PubMed 26003568

Publications 2013

Jonson I, Ougland R, Klungland A, Larsen E (2013)
Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells
Stem Cell Res, 11 (3), 1264-71
DOI 10.1016/j.scr.2013.08.010, PubMed 24041806

Jonson I, Ougland R, Larsen E (2013)
DNA repair mechanisms in Huntington's disease
Mol Neurobiol, 47 (3), 1093-102
DOI 10.1007/s12035-013-8409-7, PubMed 23361256

Publications 2012

Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A (2012)
Kinetics of endogenous mouse FEN1 in base excision repair
Nucleic Acids Res, 40 (18), 9044-59
DOI 10.1093/nar/gks673, PubMed 22810208

Ougland R, Lando D, Jonson I, Dahl JA, Moen MN, Nordstrand LM, Rognes T, Lee JT, Klungland A, Kouzarides T, Larsen E (2012)
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation
Stem Cells, 30 (12), 2672-82
DOI 10.1002/stem.1228, PubMed 22961808

Publications 2010

Møllersen L, Rowe AD, Larsen E, Rognes T, Klungland A (2010)
Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice
PLoS Genet, 6 (12), e1001242
DOI 10.1371/journal.pgen.1001242, PubMed 21170307

Nordstrand LM, Svärd J, Larsen E, Nilsen A, Ougland R, Furu K, Lien GF, Rognes T, Namekawa SH, Lee JT, Klungland A (2010)
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects
PLoS One, 5 (11), e13827
DOI 10.1371/journal.pone.0013827, PubMed 21072209

Publications 2008

Larsen E, Kleppa L, Meza TJ, Meza-Zepeda LA, Rada C, Castellanos CG, Lien GF, Nesse GJ, Neuberger MS, Laerdahl JK, William Doughty R, Klungland A (2008)
Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
Cancer Res, 68 (12), 4571-9
DOI 10.1158/0008-5472.CAN-08-0168, PubMed 18559501

Publications 2007

Larsen E, Meza TJ, Kleppa L, Klungland A (2007)
Organ and cell specificity of base excision repair mutants in mice
Mutat Res, 614 (1-2), 56-68
DOI 10.1016/j.mrfmmm.2006.01.023, PubMed 16765995

Nordstrand LM, Ringvoll J, Larsen E, Klungland A (2007)
Genome instability and DNA damage accumulation in gene-targeted mice
Neuroscience, 145 (4), 1309-17
DOI 10.1016/j.neuroscience.2006.10.059, PubMed 17218062

Publications 2006

Larsen E, Reite K, Nesse G, Gran C, Seeberg E, Klungland A (2006)
Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice
Oncogene, 25 (17), 2425-32
DOI 10.1038/sj.onc.1209284, PubMed 16369492

Publications 2004

Larsen E, Kwon K, Coin F, Egly JM, Klungland A (2004)
Transcription activities at 8-oxoG lesions in DNA
DNA Repair (Amst), 3 (11), 1457-68
DOI 10.1016/j.dnarep.2004.06.008, PubMed 15380101

Publications 2003

Larsen E, Gran C, Saether BE, Seeberg E, Klungland A (2003)
Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
Mol Cell Biol, 23 (15), 5346-53
DOI 10.1128/mcb.23.15.5346-5353.2003, PubMed 12861020

Publications 2002

Osterod M, Larsen E, Le Page F, Hengstler JG, Van Der Horst GT, Boiteux S, Klungland A, Epe B (2002)
A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
Oncogene, 21 (54), 8232-9
DOI 10.1038/sj.onc.1206027, PubMed 12447686

Publications 2000

Seeberg E, Luna L, Morland I, Eide L, Johnsen B, Larsen E, Alseth I, Dantzer F, Baynton K, Aamodt R, Kristiansen KI, Rognes T, Klungland A, Bjørås M (2000)
Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA
Cold Spring Harb Symp Quant Biol, 65, 135-42
DOI 10.1101/sqb.2000.65.135, PubMed 12760028

Publications 1999

Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, Epe B, Seeberg E, Lindahl T, Barnes DE (1999)
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
Proc Natl Acad Sci U S A, 96 (23), 13300-5
DOI 10.1073/pnas.96.23.13300, PubMed 10557315

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