Ellen Jørum


    Publications 2019

    Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Le TKC, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A (2019)
    The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients
    Pain (in press)
    DOI 10.1097/j.pain.0000000000001511, PubMed 30720580

    Publications 2018

    Kleggetveit IP, Jørum E (2018)
    Reply to the Letter to the Editor by Ly-Pen and Andréu
    Scand J Pain, 18 (4), 757
    DOI 10.1515/sjpain-2018-0118, PubMed 30145582

    Kleggetveit IP, Jørum E (2018)
    Diagnosis of carpal tunnel syndrome
    Scand J Pain, 18 (3), 333-337
    DOI 10.1515/sjpain-2018-0089, PubMed 29894306

    Namer B, Schmidt D, Eberhardt E, Maroni M, Dorfmeister E, Kleggetveit IP, Kaluza L, Meents J, Gerlach A, Lin Z, Winterpacht A, Dragicevic E, Kohl Z, Schüttler J, Kurth I, Warncke T, Jorum E, Winner B, Lampert A (2018)
    Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors
    EBioMedicine, 39, 401-408
    DOI 10.1016/j.ebiom.2018.11.042, PubMed 30503201

    Publications 2017

    Helås T, Sagafos D, Kleggetveit IP, Quiding H, Jönsson B, Segerdahl M, Zhang Z, Salter H, Schmelz M, Jørum E (2017)
    Pain thresholds, supra-threshold pain and lidocaine sensitivity in patients with erythromelalgia, including the I848Tmutation in NaV 1.7
    Eur J Pain, 21 (8), 1316-1325
    DOI 10.1002/ejp.1030, PubMed 28418213

    Namer B, Ørstavik K, Schmidt R, Mair N, Kleggetveit IP, Zeidler M, Martha T, Jorum E, Schmelz M, Kalpachidou T, Kress M, Langeslag M (2017)
    Changes in Ionic Conductance Signature of Nociceptive Neurons Underlying Fabry Disease Phenotype
    Front Neurol, 8, 335
    DOI 10.3389/fneur.2017.00335, PubMed 28769867

    Publications 2016

    Jørum E (2016)
    The Sun King's anal fistula
    Tidsskr Nor Laegeforen, 136 (14-15), 1244-7
    DOI 10.4045/tidsskr.15.0312, PubMed 27554569

    Kist AM, Sagafos D, Rush AM, Neacsu C, Eberhardt E, Schmidt R, Lunden LK, Ørstavik K, Kaluza L, Meents J, Zhang Z, Carr TH, Salter H, Malinowsky D, Wollberg P, Krupp J, Kleggetveit IP, Schmelz M, Jørum E, Lampert A, Namer B (2016)
    SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing
    PLoS One, 11 (9), e0161789
    DOI 10.1371/journal.pone.0161789, PubMed 27598514

    Kleggetveit IP, Schmidt R, Namer B, Salter H, Helås T, Schmelz M, Jørum E (2016)
    Pathological nociceptors in two patients with erythromelalgia-like symptoms and rare genetic Nav 1.9 variants
    Brain Behav, 6 (10), e00528
    DOI 10.1002/brb3.528, PubMed 27781142

    Sagafos D, Kleggetveit IP, Helås T, Schmidt R, Minde J, Namer B, Schmelz M, Jørum E (2016)
    Single-Fiber Recordings of Nociceptive Fibers in Patients With HSAN Type V With Congenital Insensitivity to Pain
    Clin J Pain, 32 (7), 636-42
    DOI 10.1097/AJP.0000000000000303, PubMed 27270876

    Publications 2015

    Horn MA, Mikaelsen KB, Ferdinandusse S, Jørum E, Mellgren SI, Retterstøl L, Wanders RJ, Tallaksen CM (2015)
    Mild phenotype in an adult male with X-linked adrenoleukodystrophy - case report
    Clin Case Rep, 4 (2), 177-81
    DOI 10.1002/ccr3.434, PubMed 26862418

    Jørum E (2015)
    Advancing methods for characterizing structure and functions of small nerve fibres in neuropathic conditions
    Scand J Pain, 10, 54-56
    DOI 10.1016/j.sjpain.2015.09.005, PubMed 28361772

    Kleggetveit IP, Skulberg PK, Jørum E (2015)
    Complex regional pain syndrome following viper-bite
    Scand J Pain, 10, 15-18
    DOI 10.1016/j.sjpain.2015.07.005, PubMed 28361765

    Lunden LK, Kleggetveit IP, Jørum E (2015)
    Delayed diagnosis and worsening of pain following orthopedic surgery in patients with complex regional pain syndrome (CRPS)
    Scand J Pain, 11, 27-33
    DOI 10.1016/j.sjpain.2015.11.004, PubMed 28850465

    Namer B, Ørstavik K, Schmidt R, Kleggetveit IP, Weidner C, Mørk C, Kvernebo MS, Kvernebo K, Salter H, Carr TH, Segerdahl M, Quiding H, Waxman SG, Handwerker HO, Torebjörk HE, Jørum E, Schmelz M (2015)
    Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7
    Pain, 156 (9), 1637-46
    DOI 10.1097/j.pain.0000000000000229, PubMed 25993546

    Publications 2014

    Horn MA, Nilsen KB, Jørum E, Mellgren SI, Tallaksen CM (2014)
    Small nerve fiber involvement is frequent in X-linked adrenoleukodystrophy
    Neurology, 82 (19), 1678-83
    DOI 10.1212/WNL.0000000000000415, PubMed 24719486

    Namer B, Schick M, Kleggetveit IP, Ørstavik K, Schmidt R, Jorum E, Torebjörk E, Handwerker H, Schmelz M (2014)
    Differential sensitization of silent nociceptors to low pH stimulation by prostaglandin E2 in human volunteers
    Eur J Pain, 19 (2), 159-66
    DOI 10.1002/ejp.532, PubMed 24890616

    Zhang Z, Schmelz M, Segerdahl M, Quiding H, Centerholt C, Juréus A, Carr TH, Whiteley J, Salter H, Kvernebo MS, Ørstavik K, Helås T, Kleggetveit IP, Lunden LK, Jørum E (2014)
    Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia
    Scand J Pain, 5 (4), 217-225
    DOI 10.1016/j.sjpain.2014.09.002, PubMed 29911575

    Publications 2013

    Haugaa KH, Vestervik TT, Andersson S, Amlie JP, Jørum E, Gjerstad L, Taubøll E (2013)
    Abnormal electroencephalograms in patients with long QT syndrome
    Heart Rhythm, 10 (12), 1877-83
    DOI 10.1016/j.hrthm.2013.09.070, PubMed 24080067

    Jørum E, Warncke T, Ørstavik K (2013)
    [Small-fibre neuropathy]
    Tidsskr Nor Laegeforen, 133 (2), 179-83
    DOI 10.4045/tidsskr.12.0160, PubMed 23344604

    Sveen KA, Karimé B, Jørum E, Mellgren SI, Fagerland MW, Monnier VM, Dahl-Jørgensen K, Hanssen KF (2013)
    Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study
    Diabetes Care, 36 (11), 3712-7
    DOI 10.2337/dc13-0788, PubMed 24026557

    Ørstavik K, Kleggetveit IP, Jørum E (2013)
    [Microneurography and research on peripheral neuropathic pain]
    Tidsskr Nor Laegeforen, 133 (3), 302-5
    DOI 10.4045/tidsskr.12.0098, PubMed 23381167

    Publications 2012

    Jørum E, Torbergsen T, Dietrichs E (2012)
    Combined testing of autonomic and sensory dysfunction in patients with unilateral facial flushing and sweating during exercise
    Neurophysiol Clin, 43 (1), 1-10
    DOI 10.1016/j.neucli.2012.09.090, PubMed 23290171

    Jørum E, Warncke T (2012)
    [Treatment of chronic non-malignant pain]
    Tidsskr Nor Laegeforen, 132 (22), 2474
    DOI 10.4045/tidsskr.12.1246, PubMed 23338018

    Kankel J, Obreja O, Kleggetveit IP, Schmidt R, Jørum E, Schmelz M, Namer B (2012)
    Differential effects of low dose lidocaine on C-fiber classes in humans
    J Pain, 13 (12), 1232-41
    DOI 10.1016/j.jpain.2012.09.008, PubMed 23182228

    Kleggetveit IP, Namer B, Schmidt R, Helås T, Rückel M, Ørstavik K, Schmelz M, Jørum E (2012)
    High spontaneous activity of C-nociceptors in painful polyneuropathy
    Pain, 153 (10), 2040-7
    DOI 10.1016/j.pain.2012.05.017, PubMed 22986070

    Publications 2011

    Schmidt R, Kleggetveit IP, Namer B, Helås T, Obreja O, Schmelz M, Jørum E (2011)
    Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients
    Pain, 153 (2), 391-8
    DOI 10.1016/j.pain.2011.10.041, PubMed 22154219

    Publications 2010

    Jørum E (2010)
    Importance of clinical neurophysiological tests in the evaluation of pain: Indispensable in complex pain conditions
    Scand J Pain, 1 (4), 177-178
    DOI 10.1016/j.sjpain.2010.09.001, PubMed 29913986

    Kleggetveit IP, Jørum E (2010)
    Large and small fiber dysfunction in peripheral nerve injuries with or without spontaneous pain
    J Pain, 11 (12), 1305-10
    DOI 10.1016/j.jpain.2010.03.004, PubMed 20488761

    Kvarstein G, Jørum E (2010)
    [The intern's vein--the patient's nightmare?]
    Tidsskr Nor Laegeforen, 130 (12), 1250-1
    DOI 10.4045/tidsskr.09.0769, PubMed 20567278

    Publications 2009

    Koht J, Bjørnarå KA, Jørum E, Tallaksen CM (2009)
    Ataxia with vitamin E deficiency in southeast Norway, case report
    Acta Neurol Scand Suppl (189), 42-5
    DOI 10.1111/j.1600-0404.2009.01214.x, PubMed 19566498

    Orstavik K, Jørum E (2009)
    Microneurographic findings of relevance to pain in patients with erythromelalgia and patients with diabetic neuropathy
    Neurosci Lett, 470 (3), 180-4
    DOI 10.1016/j.neulet.2009.05.061, PubMed 19481586

    Publications 2008

    Namer B, Kleggetveit IP, Handwerker H, Schmelz M, Jorum E (2008)
    Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury
    Pain, 139 (1), 63-72
    DOI 10.1016/j.pain.2008.03.007, PubMed 18440147

    Publications 2007

    Eide PK, Sorteberg W, Meling T, Jörum E, Hald J, Stubhaug A (2007)
    From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage
    Acta Anaesthesiol Scand, 51 (4), 501-4
    DOI 10.1111/j.1399-6576.2007.01269.x, PubMed 17378790

    Publications 2006

    Jørum E, Schmelz M (2006)
    Chapter 29 Microneurography in the assessment of neuropathic pain
    Handb Clin Neurol, 81, 427-38
    DOI 10.1016/S0072-9752(06)80033-3, PubMed 18808851

    Jørum E, Ørstavik K, Schmidt R, Namer B, Carr RW, Kvarstein G, Hilliges M, Handwerker H, Torebjörk E, Schmelz M (2006)
    Catecholamine-induced excitation of nociceptors in sympathetically maintained pain
    Pain, 127 (3), 296-301
    DOI 10.1016/j.pain.2006.08.022, PubMed 16997471

    Ørstavik K, Namer B, Schmidt R, Schmelz M, Hilliges M, Weidner C, Carr RW, Handwerker H, Jørum E, Torebjörk HE (2006)
    Abnormal function of C-fibers in patients with diabetic neuropathy
    J Neurosci, 26 (44), 11287-94
    DOI 10.1523/JNEUROSCI.2659-06.2006, PubMed 17079656

    Ørstavik K, Norheim I, Jørum E (2006)
    Pain and small-fiber neuropathy in patients with hypothyroidism
    Neurology, 67 (5), 786-91
    DOI 10.1212/01.wnl.0000234035.13779.4a, PubMed 16966538

    Publications 2005

    Jørum E (2005)
    [Assessment of neuropathic pain]
    Tidsskr Nor Laegeforen, 125 (19), 2652-4
    PubMed 16215613

    Publications 2004

    Cruccu G, Anand P, Attal N, Garcia-Larrea L, Haanpää M, Jørum E, Serra J, Jensen TS (2004)
    EFNS guidelines on neuropathic pain assessment
    Eur J Neurol, 11 (3), 153-62
    DOI 10.1111/j.1468-1331.2004.00791.x, PubMed 15009162

    Orstavik K, Mørk C, Kvernebo K, Jørum E (2004)
    Pain in primary erythromelalgia--a neuropathic component?
    Pain, 110 (3), 531-8
    DOI 10.1016/j.pain.2004.03.030, PubMed 15288393

    Publications 2003

    Harbo SO, Jørum E, Roald HE (2003)
    Reduction mammaplasty: a prospective study of symptom relief and alterations of skin sensibility
    Plast Reconstr Surg, 111 (1), 103-10; discussion 111-2
    DOI 10.1097/01.PRS.0000037749.88018.21, PubMed 12496570

    Jørum E, Warncke T, Stubhaug A (2003)
    Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine--a double-blind, cross-over comparison with alfentanil and placebo
    Pain, 101 (3), 229-35
    DOI 10.1016/S0304-3959(02)00122-7, PubMed 12583865

    Ørstavik K, Weidner C, Schmidt R, Schmelz M, Hilliges M, Jørum E, Handwerker H, Torebjörk E (2003)
    Pathological C-fibres in patients with a chronic painful condition
    Brain, 126 (Pt 3), 567-78
    DOI 10.1093/brain/awg060, PubMed 12566278

    Publications 2002

    Jorum E (2002)
    Assessment of pain and sensory abnormalities in patients with spinal cord injury
    PROG PAIN RES MANAG, 23, 39-51

    Publications 2000

    Warncke T, Stubhaug A, Jørum E (2000)
    Preinjury treatment with morphine or ketamine inhibits the development of experimentally induced secondary hyperalgesia in man
    Pain, 86 (3), 293-303
    DOI 10.1016/S0304-3959(00)00260-8, PubMed 10812259

    Publications 1997

    Warncke T, Jørum E, Stubhaug A (1997)
    Local treatment with the N-methyl-D-aspartate receptor antagonist ketamine, inhibit development of secondary hyperalgesia in man by a peripheral action
    Neurosci Lett, 227 (1), 1-4
    DOI 10.1016/S0304-3940(97)00263-2, PubMed 9178844

    Warncke T, Stubhaug A, Jørum E (1997)
    Ketamine, an NMDA receptor antagonist, suppresses spatial and temporal properties of burn-induced secondary hyperalgesia in man: a double-blind, cross-over comparison with morphine and placebo
    Pain, 72 (1-2), 99-106
    DOI 10.1016/S0304-3959(97)00006-7, PubMed 9272793

    Publications 1996

    Eide PK, Jørum E, Stenehjem AE (1996)
    Somatosensory findings in patients with spinal cord injury and central dysaesthesia pain
    J Neurol Neurosurg Psychiatry, 60 (4), 411-5
    DOI 10.1136/jnnp.60.4.411, PubMed 8774406

    Publications 1994

    Eide PK, Jørum E, Stubhaug A, Bremnes J, Breivik H (1994)
    Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo
    Pain, 58 (3), 347-54
    DOI 10.1016/0304-3959(94)90129-5, PubMed 7838584

    Mackel R, Brink E, Jorum E, Aisen M (1994)
    Properties of cutaneous afferents during recovery from Guillain-Barré syndrome
    Brain, 117 ( Pt 1), 169-83
    DOI 10.1093/brain/117.1.169, PubMed 8149210

    Publications 1992

    Lundberg LE, Jørum E, Holm E, Torebjörk HE (1992)
    Intra-neural electrical stimulation of cutaneous nociceptive fibres in humans: effects of different pulse patterns on magnitude of pain
    Acta Physiol Scand, 146 (1), 41-8
    DOI 10.1111/j.1748-1716.1992.tb09391.x, PubMed 1442126

    Publications 1991

    Mackel R, Iriki A, Jorum E, Asanuma H (1991)
    Neurons of the pretectal area convey spinal input to the motor thalamus of the cat
    Exp Brain Res, 84 (1), 12-24
    PubMed 1855554

    Publications 1989

    Jørum E, Lundberg LE, Torebjörk HE (1989)
    Peripheral projections of nociceptive unmyelinated axons in the human peroneal nerve
    J Physiol, 416, 291-301
    PubMed 2607452

    Wahren LK, Torebjörk E, Jörum E (1989)
    Central suppression of cold-induced C fibre pain by myelinated fibre input
    Pain, 38 (3), 313-9
    PubMed 2812842

    Publications 1988

    Jørum E (1988)
    The analgesic effect of peripheral nerve stimulation in various tests of nociception in rats
    Acta Physiol Scand, 133 (2), 131-8
    DOI 10.1111/j.1748-1716.1988.tb08392.x, PubMed 3265842

    Jørum E (1988)
    Analgesia or hyperalgesia following stress correlates with emotional behavior in rats
    Pain, 32 (3), 341-8
    PubMed 3362568

    Jørum E (1988)
    Noradrenergic mechanisms in mediation of stress-induced hyperalgesia in rats
    Pain, 32 (3), 349-55
    PubMed 2834686

    Jørum E, Shyu BC (1988)
    Analgesia by low-frequency nerve stimulation mediated by low-threshold afferents in rats
    Pain, 32 (3), 357-66
    DOI 10.1016/0304-3959(88)90048-6, PubMed 3362569

    Publications 1987

    Jørum E, Shyu BC (1987)
    Course and mode of action of descending system conveying nucleus raphe magnus induced inhibition of flexion reflex in rats
    Acta Physiol Scand, 131 (4), 489-97
    DOI 10.1111/j.1748-1716.1987.tb08268.x, PubMed 2964771

    Publications 1979

    Acupunct. Electro-Ther. Res., 4 (3-4), 221-234

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