Jochen Büchner

  • Senior consultant; PhD
 

Publications 2021

Andersen AM, Bergan S, Gedde-Dahl T, Buechner J, Vethe NT (2021)
Fast and reliable quantification of busulfan in blood plasma using two-channel liquid chromatography tandem mass spectrometry: Validation of assay performance in the presence of drug formulation excipients
J Pharm Biomed Anal, 203, 114216
DOI 10.1016/j.jpba.2021.114216, PubMed 34182411

Balduzzi A, Bönig H, Jarisch A, Nava T, Ansari M, Cattoni A, Prunotto G, Lucchini G, Krivan G, Matic T, Kalwak K, Yesilipek A, Ifversen M, Svec P, Buechner J, Vettenranta K, Meisel R, Lawitschka A, Peters C, Gibson B, Dalissier A, Corbacioglu S, Willasch A, Dalle JH, Bader P et al. (2021)
Correction: ABO incompatibile graft management in pediatric transplantation
Bone Marrow Transplant, 56 (1), 297
DOI 10.1038/s41409-020-01012-z, PubMed 32753704

Buechner J, Grupp SA, Hiramatsu H, Teachey DT, Rives S, Laetsch TW, Yanik GA, Wood P, Awasthi R, Yi L, Chassot-Agostinho A, Eldjerou LK, De Moerloose B (2021)
Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy
Blood Adv, 5 (2), 593-601
DOI 10.1182/bloodadvances.2020002757, PubMed 33496754

Burkhardt B, Taj M, Garnier N, Minard-Colin V, Hazar V, Mellgren K, Osumi T, Fedorova A, Myakova N, Verdu-Amoros J, Andres M, Kabickova E, Attarbaschi A, Chiang AKS, Bubanska E, Donska S, Hjalgrim LL, Wachowiak J, Pieczonka A, Uyttebroeck A, Lazic J, Loeffen J, Buechner J, Niggli F, Csoka M et al. (2021)
Treatment and Outcome Analysis of 639 Relapsed Non-Hodgkin Lymphomas in Children and Adolescents and Resulting Treatment Recommendations
Cancers (Basel), 13 (9)
DOI 10.3390/cancers13092075, PubMed 33923026

Ifversen M, Meisel R, Sedlacek P, Kalwak K, Sisinni L, Hutt D, Lehrnbecher T, Balduzzi A, Diesch T, Jarisch A, Güngör T, Stein J, Yaniv I, Bonig H, Kuhlen M, Ansari M, Nava T, Dalle JH, Diaz-de-Heredia C, Trigoso E, Falkenberg U, Hartmann M, Deiana M, Canesi M, Broggi C et al. (2021)
Supportive Care During Pediatric Hematopoietic Stem Cell Transplantation: Prevention of Infections. A Report From Workshops on Supportive Care of the Paediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)
Front Pediatr, 9, 705179
DOI 10.3389/fped.2021.705179, PubMed 34395344

Kozyra EJ, Gohring G, Hickstein DD, Calvo KR, DiNardo CD, Dworzak M, de Haas V, Stary J, Hasle H, Shimamura A, Fleming MD, Inaba H, Lewis S, Hsu AP, Holland SM, Arnold DE, Mecucci C, Keel SB, Bertuch AA, Tawana K, Barzilai-Birenboim S, Hirabayashi S, Onozawa M, Lei S, Alaiz H et al. (2021)
Association of Unbalanced Translocation der(1;7) with Germline GATA2 Mutations
Blood (in press)
DOI 10.1182/blood.2021012781, PubMed 34469508

Levine JE, Grupp SA, Pulsipher MA, Dietz AC, Rives S, Myers GD, August KJ, Verneris MR, Buechner J, Laetsch TW, Bittencourt H, Baruchel A, Boyer MW, De Moerloose B, Qayed M, Davies SM, Phillips CL, Driscoll TA, Bader P, Schlis K, Wood PA, Mody R, Yi L, Leung M, Eldjerou LK et al. (2021)
Pooled safety analysis of tisagenlecleucel in children and young adults with B cell acute lymphoblastic leukemia
J Immunother Cancer, 9 (8)
DOI 10.1136/jitc-2020-002287, PubMed 34353848

Panagopoulos I, Andersen K, Eilert-Olsen M, Zeller B, Munthe-Kaas MC, Buechner J, Osnes LTN, Micci F, Heim S (2021)
Therapy-induced Deletion in 11q23 Leading to Fusion of KMT2A With ARHGEF12 and Development of B Lineage Acute Lymphoplastic Leukemia in a Child Treated for Acute Myeloid Leukemia Caused by t(9;11)(p21;q23)/KMT2A-MLLT3
Cancer Genomics Proteomics, 18 (1), 67-81
DOI 10.21873/cgp.20242, PubMed 33419897

Sahoo SS, Pastor VB, Goodings C, Voss RK, Kozyra EJ, Szvetnik A, Noellke P, Dworzak M, Starý J, Locatelli F, Masetti R, Schmugge M, De Moerloose B, Catala A, Kállay K, Turkiewicz D, Hasle H, Buechner J, Jahnukainen K, Ussowicz M, Polychronopoulou S, Smith OP, Fabri O, Barzilai S, de Haas V et al. (2021)
Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes
Nat Med, 27 (10), 1806-1817
DOI 10.1038/s41591-021-01511-6, PubMed 34621053

Willasch AM, Peters C, Sedláček P, Dalle JH, Kitra-Roussou V, Yesilipek A, Wachowiak J, Lankester A, Prete A, Hamidieh AA, Ifversen M, Buechner J, Kriván G, Hamladji RM, Diaz-de-Heredia C, Skorobogatova E, Michel G, Locatelli F, Bertaina A, Veys P, Dupont S, Or R, Güngör T, Aleinikova O, Sufliarska S et al. (2021)
Correction: Myeloablative conditioning for allo-HSCT in pediatric ALL: FTBI or chemotherapy?-A multicenter EBMT-PDWP study
Bone Marrow Transplant, 56 (10), 2615
DOI 10.1038/s41409-021-01424-5, PubMed 34413474

Publications 2020

Balduzzi A, Bönig H, Jarisch A, Nava T, Ansari M, Cattoni A, Prunotto G, Lucchini G, Krivan G, Matic T, Kalwak K, Yesilipek A, Ifversen M, Svec P, Buechner J, Vettenranta K, Meisel R, Lawitschka A, Peters C, Gibson B, Dalissier A, Corbacioglu S, Willasch A, Dalle JH, Bader P et al. (2020)
ABO incompatibile graft management in pediatric transplantation
Bone Marrow Transplant, 56 (1), 84-90
DOI 10.1038/s41409-020-0981-7, PubMed 32594103

Nava T, Ansari M, Dalle JH, de Heredia CD, Güngör T, Trigoso E, Falkenberg U, Bertaina A, Gibson B, Jarisch A, Balduzzi A, Boenig H, Krivan G, Vettenranta K, Matic T, Buechner J, Kalwak K, Lawitschka A, Yesilipek A, Lucchini G, Peters C, Turkiewicz D, Niinimäki R, Diesch T, Lehrnbecher T et al. (2020)
Correction: Supportive care during pediatric hematopoietic stem cell transplantation: beyond infectious diseases. A report from workshops on supportive care of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)
Bone Marrow Transplant, 55 (6), 1214
DOI 10.1038/s41409-020-0838-0, PubMed 32080355

Nava T, Ansari M, Dalle JH, de Heredia CD, Güngör T, Trigoso E, Falkenberg U, Bertaina A, Gibson B, Jarisch A, Balduzzi A, Boenig H, Krivan G, Vettenranta K, Matic T, Buechner J, Kalwak K, Lawitschka A, Yesilipek A, Lucchini G, Peters C, Turkiewicz D, Niinimäki R, Diesch T, Lehrnbecher T et al. (2020)
Supportive care during pediatric hematopoietic stem cell transplantation: beyond infectious diseases. A report from workshops on supportive care of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)
Bone Marrow Transplant, 55 (6), 1126-1136
DOI 10.1038/s41409-020-0818-4, PubMed 32029909

Peters C, Dalle JH, Locatelli F, Poetschger U, Sedlacek P, Buechner J, Shaw PJ, Staciuk R, Ifversen M, Pichler H, Vettenranta K, Svec P, Aleinikova O, Stein J, Güngör T, Toporski J, Truong TH, Diaz-de-Heredia C, Bierings M, Ariffin H, Essa M, Burkhardt B, Schultz K, Meisel R, Lankester A et al. (2020)
Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study
J Clin Oncol, 39 (4), 295-307
DOI 10.1200/JCO.20.02529, PubMed 33332189

Strand J, Gul KA, Erichsen HC, Lundman E, Berge MC, Trømborg AK, Sørgjerd LK, Ytre-Arne M, Hogner S, Halsne R, Gaup HJ, Osnes LT, Kro GAB, Sorte HS, Mørkrid L, Rowe AD, Tangeraas T, Jørgensen JV, Alme C, Bjørndalen TEH, Rønnestad AE, Lang AM, Rootwelt T, Buechner J, Øverland T et al. (2020)
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152

Willasch AM, Peters C, Sedláček P, Dalle JH, Kitra-Roussou V, Yesilipek A, Wachowiak J, Lankester A, Prete A, Hamidieh AA, Ifversen M, Buechner J, Kriván G, Hamladji RM, Diaz-de-Heredia C, Skorobogatova E, Michel G, Locatelli F, Bertaina A, Veys P, Dupont S, Or R, Güngör T, Aleinikova O, Sufliarska S et al. (2020)
Myeloablative conditioning for allo-HSCT in pediatric ALL: FTBI or chemotherapy?-A multicenter EBMT-PDWP study
Bone Marrow Transplant, 55 (8), 1540-1551
DOI 10.1038/s41409-020-0854-0, PubMed 32203263

Wolska-Kusnierz B, Pastorczak A, Fendler W, Wakulinska A, Dembowska-Baginska B, Heropolitanska-Pliszka E, Piątosa B, Pietrucha B, Kałwak K, Ussowicz M, Pieczonka A, Drabko K, Lejman M, Koltan S, Gozdzik J, Styczynski J, Fedorova A, Miakova N, Deripapa E, Kostyuchenko L, Krenova Z, Hlavackova E, Gennery AR, Sykora KW, Ghosh S et al. (2020)
Hematopoietic Stem Cell Transplantation Positively Affects the Natural History of Cancer in Nijmegen Breakage Syndrome
Clin Cancer Res, 27 (2), 575-584
DOI 10.1158/1078-0432.CCR-20-2574, PubMed 33082212

Publications 2019

Bonig H, Kuçi Z, Kuçi S, Bakhtiar S, Basu O, Bug G, Dennis M, Greil J, Barta A, Kállay KM, Lang P, Lucchini G, Pol R, Schulz A, Sykora KW, Teichert von Luettichau I, Herter-Sprie G, Ashab Uddin M, Jenkin P, Alsultan A, Buechner J, Stein J, Kelemen A, Jarisch A, Soerensen J et al. (2019)
Children and Adults with Refractory Acute Graft-versus-Host Disease Respond to Treatment with the Mesenchymal Stromal Cell Preparation "MSC-FFM"-Outcome Report of 92 Patients
Cells, 8 (12)
DOI 10.3390/cells8121577, PubMed 31817480

Ifversen M, Turkiewicz D, Marquart HV, Winiarski J, Buechner J, Mellgren K, Arvidson J, Rascon J, Körgvee LT, Madsen HO, Abrahamsson J, Lund B, Jonsson OG, Heilmann C, Heyman M, Schmiegelow K, Vettenranta K (2019)
Low burden of minimal residual disease prior to transplantation in children with very high risk acute lymphoblastic leukaemia: The NOPHO ALL2008 experience
Br J Haematol, 184 (6), 982-993
DOI 10.1111/bjh.15761, PubMed 30680711

Laetsch TW, Myers GD, Baruchel A, Dietz AC, Pulsipher MA, Bittencourt H, Buechner J, De Moerloose B, Davis KL, Nemecek E, Driscoll T, Mechinaud F, Boissel N, Rives S, Bader P, Peters C, Sabnis HS, Grupp SA, Yanik GA, Hiramatsu H, Stefanski HE, Rasouliyan L, Yi L, Shah S, Zhang J et al. (2019)
Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial
Lancet Oncol, 20 (12), 1710-1718
DOI 10.1016/S1470-2045(19)30493-0, PubMed 31606419

Pearson ADJ, Scobie N, Norga K, Ligas F, Chiodin D, Burke A, Minard-Colin V, Adamson P, Marshall LV, Balakumaran A, Benettaib B, Bhargava P, Bollard CM, Bolotin E, Bomken S, Buechner J, Burkhardt B, Caron H, Copland C, Demolis P, Egorov A, Farhan M, Zugmaier G, Gross T, Horton-Taylor D et al. (2019)
ACCELERATE and European Medicine Agency Paediatric Strategy Forum for medicinal product development for mature B-cell malignancies in children
Eur J Cancer, 110, 74-85
DOI 10.1016/j.ejca.2019.01.013, PubMed 30772656

Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319

Publications 2018

Bader P, Kuçi Z, Bakhtiar S, Basu O, Bug G, Dennis M, Greil J, Barta A, Kállay KM, Lang P, Lucchini G, Pol R, Schulz A, Sykora KW, von Luettichau I, Herter-Sprie G, Uddin MA, Jenkin P, Alsultan A, Buechner J, Stein J, Kelemen A, Jarisch A, Soerensen J, Salzmann-Manrique E et al. (2018)
Effective treatment of steroid and therapy-refractory acute graft-versus-host disease with a novel mesenchymal stromal cell product (MSC-FFM)
Bone Marrow Transplant, 53 (7), 852-862
DOI 10.1038/s41409-018-0102-z, PubMed 29379171

Buechner J, Kersten MJ, Fuchs M, Salmon F, Jäger U (2018)
Chimeric Antigen Receptor-T Cell Therapy: Practical Considerations for Implementation in Europe
Hemasphere, 2 (1), e18
DOI 10.1097/HS9.0000000000000018, PubMed 31723747

Diep PP, Melberg HO, Brinch L, Buechner J, Fløisand Y, Gedde-Dahl T, Loge JH, Tjønnfjord GE, Ruud E (2018)
Cost-utility of allogeneic hematopoietic stem cell transplantation in Norway
Bone Marrow Transplant, 53 (5), 657-660
DOI 10.1038/s41409-018-0091-y, PubMed 29358600

Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH et al. (2018)
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
N Engl J Med, 378 (5), 439-448
DOI 10.1056/NEJMoa1709866, PubMed 29385370

Orlando EJ, Han X, Tribouley C, Wood PA, Leary RJ, Riester M, Levine JE, Qayed M, Grupp SA, Boyer M, De Moerloose B, Nemecek ER, Bittencourt H, Hiramatsu H, Buechner J, Davies SM, Verneris MR, Nguyen K, Brogdon JL, Bitter H, Morrissey M, Pierog P, Pantano S, Engelman JA, Winckler W (2018)
Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia
Nat Med, 24 (10), 1504-1506
DOI 10.1038/s41591-018-0146-z, PubMed 30275569

Publications 2017

Slack J, Albert MH, Balashov D, Belohradsky BH, Bertaina A, Bleesing J, Booth C, Buechner J, Buckley RH, Ouachée-Chardin M, Deripapa E, Drabko K, Eapen M, Feuchtinger T, Finocchi A, Gaspar HB, Ghosh S, Gillio A, Gonzalez-Granado LI, Grunebaum E, Güngör T, Heilmann C, Helminen M, Higuchi K, Imai K et al. (2017)
Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders
J Allergy Clin Immunol, 141 (1), 322-328.e10
DOI 10.1016/j.jaci.2017.02.036, PubMed 28392333

Publications 2016

Bartelheim K, Nemes K, Seeringer A, Kerl K, Buechner J, Boos J, Graf N, Dürken M, Gerss J, Hasselblatt M, Kortmann RD, Teichert von Luettichau I, Nagel I, Nygaard R, Oyen F, Quiroga E, Schlegel PG, Schmid I, Schneppenheim R, Siebert R, Solano-Paez P, Timmermann B, Warmuth-Metz M, Frühwald MC (2016)
Improved 6-year overall survival in AT/RT - results of the registry study Rhabdoid 2007
Cancer Med, 5 (8), 1765-75
DOI 10.1002/cam4.741, PubMed 27228363

Publications 2013

Panagopoulos I, Micci F, Thorsen J, Haugom L, Buechner J, Kerndrup G, Tierens A, Zeller B, Heim S (2013)
Fusion of ZMYND8 and RELA genes in acute erythroid leukemia
PLoS One, 8 (5), e63663
DOI 10.1371/journal.pone.0063663, PubMed 23667654

Publications 2012

Buechner J, Einvik C (2012)
N-myc and noncoding RNAs in neuroblastoma
Mol Cancer Res, 10 (10), 1243-53
DOI 10.1158/1541-7786.MCR-12-0244, PubMed 22936790

Publications 2011

Haug BH, Henriksen JR, Buechner J, Geerts D, Tømte E, Kogner P, Martinsson T, Flægstad T, Sveinbjørnsson B, Einvik C (2011)
MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
Carcinogenesis, 32 (7), 1005-12
DOI 10.1093/carcin/bgr073, PubMed 21572098

Henriksen JR, Buechner J, Løkke C, Flægstad T, Einvik C (2011)
Inhibition of gene function in mammalian cells using short-hairpin RNA (shRNA)
Methods Mol Biol, 703, 189-204
DOI 10.1007/978-1-59745-248-9_13, PubMed 21125491

Henriksen JR, Haug BH, Buechner J, Tømte E, Løkke C, Flaegstad T, Einvik C (2011)
Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
BMC Dev Biol, 11, 1
DOI 10.1186/1471-213X-11-1, PubMed 21194500

Publications 2010

Buechner J, Henriksen JR, Haug BH, Tømte E, Flaegstad T, Einvik C (2010)
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
Differentiation, 81 (1), 25-34
DOI 10.1016/j.diff.2010.09.184, PubMed 20980091

Kranendijk M, Struys EA, Gibson KM, Wickenhagen WV, Abdenur JE, Buechner J, Christensen E, de Kremer RD, Errami A, Gissen P, Gradowska W, Hobson E, Islam L, Korman SH, Kurczynski T, Maranda B, Meli C, Rizzo C, Sansaricq C, Trefz FK, Webster R, Jakobs C, Salomons GS (2010)
Evidence for genetic heterogeneity in D-2-hydroxyglutaric aciduria
Hum Mutat, 31 (3), 279-83
DOI 10.1002/humu.21186, PubMed 20020533

Publications 2009

Berg T, Kalsaas AH, Buechner J, Busund LT (2009)
Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript
Cancer Genet Cytogenet, 194 (1), 53-7
DOI 10.1016/j.cancergencyto.2009.06.002, PubMed 19737655

Publications 2003

Tartaglia M, Niemeyer CM, Fragale A, Song X, Buechner J, Jung A, Hählen K, Hasle H, Licht JD, Gelb BD (2003)
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
Nat Genet, 34 (2), 148-50
DOI 10.1038/ng1156, PubMed 12717436

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